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Total 29472 results found since Jan 2013.
What to use instead of NICE Evidence Search - a first thought
I have been promoting NICE Evidence Search much more systematically this year to " my " first year undergraduates in their first library session. It is also on the resource lists I ' ve made for each of their courses. I like the idea that there is one source, where all the results have been evaluated by health information professionals, and I ' ve suggested it ' s a good first place to search for any health topic. But NICE Evidence Search is closing at the end of March 2022. So what to use instead?NICE Evidence Search has two lists of sources, one of sites where some of the content is...
Source: Browsing - February 9, 2022 Category: Databases & Libraries Tags: NICE Evidence Search Source Type: blogs
What to use instead of NICE Evidence Search - some recommendations (sort of)
In an earlier post I searched NICE Evidence Search (closing at the end of March 2022) and then a number of other sources to see which other sources would find the material.I found 27 results (vertigo epley was the search) in NICE Evidence Search. 5 were systematic reviews from DARE, which I decided I was not too worried about, as DARE has not been updated for some timeThen there were results from PubMed, Cochrane, BestBets, CKS, four health organisations, Patient.info, NICE and the Royal Australian College of GPs.SearchingCochraneitself found one more Cochrane review than NICE Evidence Search did. So, more...
Source: Browsing - March 10, 2022 Category: Databases & Libraries Tags: NICE Evidence Search Source Type: blogs
Preparation of Modified Chitosan-Based Nanoparticles for Efficient Delivery of Doxorubicin and/or Cisplatin to Breast Cancer Cells
CONCLUSION: These novel pH sensitive nanoparticles proved to be a promising Nano- drug delivery for tumor-targeted delivery of DOX.PMID:35081892 | DOI:10.2174/1568009622666220126100532
Source: Current Cancer Drug Targets - January 27, 2022 Category: Cancer & Oncology Authors: Sina M Matalqah Khalid Aiedeh Nizar M Mhaidat Karem H Alzoubi Belal A Al-Husein Source Type: research
Influence of the Physical Inclusion of ZrO < sub > 2 < /sub > /TiO < sub > 2 < /sub > Nanoparticles on Physical, Mechanical, and Morphological Characteristics of PMMA-Based Interim Restorative Material
Biomed Res Int. 2022 Aug 19;2022:1743019. doi: 10.1155/2022/1743019. eCollection 2022.ABSTRACTPolymethyl methacrylate (PMMA) is often used in restorative dentistry for its easy fabrication, aesthetics, and low cost for interim restorations. However, poor mechanical properties to withstand complex masticatory forces are a concern for clinicians. Therefore, this study aimed to modify a commercially available PMMA-based temporary restorative material by adding TiO2 and ZrO2 nanoparticles in different percentages as fillers and to investigate its physio-mechanical properties. Different percentages (0, 0.5, 1.5, and 3.0 wt%) of...
Source: Biomed Res - August 29, 2022 Category: Research Authors: Ali Alrahlah Rawaiz Khan Fahim Vohra Ibrahim M Alqahtani Adel A Alruhaymi Sajjad Haider Abdel-Basit Al-Odayni Waseem Sharaf Saeed H C Ananda Murthy Leonel S Bautista Source Type: research
Combined toxic effects of environmental predominant microplastics and ZnO nanoparticles in freshwater snail Pomaceae paludosa
In this study, the toxic effects of individual and combined (28 days) exposure with zinc oxide nanoparticles and polypropylene microplastics were assessed in freshwater snail Pomeacea paludosa. After the experiment, the toxic effect was evaluated by the estimation of vital biomarkers activities including antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT), glutathione S-transferase (GST), oxidative stress in carbonyl protein (CP), lipid peroxidation (LPO), and digestive enzymes (esterase and alkaline phosphatase). Chronic exposure to pollutants in snails causes increased reactive oxygen species level (ROS) and ...
Source: Environmental Pollution - March 12, 2023 Category: Environmental Health Authors: Jeyaraj Jeyavani Baskaralingam Vaseeharan Source Type: research
Antimicrobial screening of silver nanoparticles synthesized by marine cyanobacterium Phormidium formosum.
Conclusion: The results confirmed that AgNPs can act as a powerful antimicrobial agent against fish and human pathogens.
PMID: 32685121 [PubMed]
Source: Iranian Journal of Microbiology - July 22, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research
IJERPH, Vol. 17, Pages 1005: Exposure of CuO Nanoparticles Contributes to Cellular Apoptosis, Redox Stress, and Alzheimer ’s Aβ Amyloidosis
This study provides evidence that CuONP induces neuronal cell apoptosis, discerns a likely p53-dependent apoptosis pathway and builds out the relationship between nanoparticles and Alzheimer&rsquo;s disease (AD) through the involvement of reactive oxygen species (ROS) and increased A&beta; levels in SH-SY5Y and H4 cells. Our results implicate that exposure to CuONP may be an environmental risk factor for AD. For public health concerns, regulation for environmental or occupational exposure of CuONP are thus warranted given AD has already become a pandemic.
Source: International Journal of Environmental Research and Public Health - February 4, 2020 Category: Environmental Health Authors: Ying Shi Alexander R. Pilozzi Xudong Huang Tags: Article Source Type: research
Neurotoxicity of four frequently used nanoparticles: a systematic review to reveal the missing data
Arch Toxicol. 2022 Mar 12. doi: 10.1007/s00204-022-03233-1. Online ahead of print.ABSTRACTSystemic exposure to nanoparticles (NPs) adversely affects different organs, including the nervous system. We systematically extracted data from publication on PubMed and Embase database up to the year 2020, and analyzed in vitro and in vivo neurotoxicity of 4 of the most well studied NPs (silver NPs, carbon-based NPs, iron NPs and silica NPs). A relatively good correlation was observed between in vitro and in vivo effects, including genotoxicity, oxidative stress, apoptosis and pro-inflammatory effects. However, crucial knowledge gap...
Source: Archives of Toxicology - March 12, 2022 Category: Toxicology Authors: Jia-You Gong Matthew G Holt Peter H M Hoet Manosij Ghosh Source Type: research
Enhancing the function of PLGA-collagen scaffold by incorporating TGF- β1-loaded PLGA-PEG-PLGA nanoparticles for cartilage tissue engineering using human dental pulp stem cells
This study evaluates various physicochemical aspects of fabricated scaffolds by 1HNMR, FT-IR, SEM, BET, and DLS methods. The physicochemical features of the developed scaffolds, including porosity, density, degradation, swelling ratio, mechanical properties, morphologies, BET, ELISA, and cytotoxicity were assessed. The cell viability was investigated with the MTT test. Chondrogenic differentiation was assessed via Alcian blue staining and RT-PCR. In real-time PCR testing, the expression of Sox-9, collagen type II, and aggrecan genes was monitored. According to the results, human dental pulp stem cells (hDPSCs) exhibited hi...
Source: Cell Research - June 1, 2022 Category: Cytology Authors: Parisa Ghandforoushan Jalal Hanaee Zahra Aghazadeh Mohammad Samiei Amir Mohammad Navali Ali Khatibi Soodabeh Davaran Source Type: research
