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Total 15962 results found since Jan 2013.

Glutathione-Triggered catalytic response of Copper-Iron mixed oxide Nanoparticles. Leveraging tumor microenvironment conditions for chemodynamic therapy
J Colloid Interface Sci. 2022 Mar 11;617:704-717. doi: 10.1016/j.jcis.2022.03.036. Online ahead of print.ABSTRACTHeterogeneous catalysis has emerged as a promising alternative for the development of new cancer therapies. In addition, regarding the tumor microenvironment as a reactor with very specific chemical features has provided a new perspective in the search for catalytic nanoarchitectures with specific action against chemical species playing a key role in tumor metabolism. One of these species is glutathione (GSH), whose depletion is the cornerstone of emerging strategies in oncology, since this metabolite plays a pi...
Source: Cell Research - March 22, 2022 Category: Cytology Authors: Javier Bonet-Aleta Maria Sancho-Albero Javier Calzada-Funes Silvia Irusta Pilar Martin-Duque Jose L Hueso Jesus Santamaria Source Type: research

Molecules, Vol. 28, Pages 3228: Therapeutic Potential of Albumin Nanoparticles Encapsulated Visnagin in MDA-MB-468 Triple-Negative Breast Cancer Cells
iah Pooi Ling Mok Breast cancer is among the most recurrent malignancies, and its prevalence is rising. With only a few treatment options available, there is an immediate need to search for better alternatives. In this regard, nanotechnology has been applied to develop potential chemotherapeutic techniques, particularly for cancer therapy. Specifically, albumin-based nanoparticles are a developing platform for the administration of diverse chemotherapy drugs owing to their biocompatibility and non-toxicity. Visnagin, a naturally derived furanochromone, treats cancers, epilepsy, angina, coughs, and inflammatory illnes...
Source: Molecules - April 4, 2023 Category: Chemistry Authors: Abdullah Alsrhani Abozer Y. Elderdery Badr Alzahrani Nasser A. N. Alzerwi Maryam Musleh Althobiti Musaed Rayzah Bandar Idrees Ahmed M. E. Elkhalifa Suresh K. Subbiah Pooi Ling Mok Tags: Article Source Type: research

A nanotechnology based strategy to increase the efficiency of cancer diagnosis and therapy: Folate conjugated gold nanoparticles.
CONCLUSION: This review identifies the important roles of F-AuNPs in current cancer researches which are undertaken worldwide. The findings of this review confirm that F-AuNP is a new theranostic agent which has great potentials for simultaneous cancer therapy and diagnosis. PMID: 28799495 [PubMed - as supplied by publisher]
Source: Current Medicinal Chemistry - August 10, 2017 Category: Chemistry Authors: Beik J, Khademi S, Attaran N, Sarkar S, Shakeri-Zadeh A, Ghaznavi H, Ghadiri H Tags: Curr Med Chem Source Type: research

Development of Drug Delivery Technology and Nanomedicine by Using Gold Nanoparticles
Yakugaku Zasshi. 2021;141(3):323-326. doi: 10.1248/yakushi.20-00179-3.ABSTRACTNanomedicine is a new medical field involving the use of nanoparticles. Early examples of biocompatible nanomedicines include liposomes (Doxil®) and albumin nanoparticles (Abraxane®), and promising new nanomedicines include nanocarriers such as nanomicelles and nanoemulsions. A new trend towards the use of metal-based nanoparticles, including gold nanoparticles, has led to global clinical trials. These particles exhibit novel properties compared to conventional nanomedicines such as liposomes and albumin nanoparticles. These properties hold pro...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 1, 2021 Category: Drugs & Pharmacology Authors: Tetsuya Ozeki Tatsuaki Tagami Source Type: research