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Total 30775 results found since Jan 2013.
Smartphone use and its association with body image distortion and weight loss behaviours among adolescents in Saudi Arabia
CONCLUSION: Adequate parental advice is required to assist teenagers in developing healthy smartphone usage practices. Digital platform companies may increase their social responsibility for the information generated and delivered on their networks, boosting its beneficial effect.PMID:37599551 | DOI:10.3233/THC-230756
Source: Technology and Health Care - August 21, 2023 Category: Medical Devices Authors: Reem A Algahtani Ziad S AlSaadi Zainah A Al-Qahtani Abdulaziz M Al-Garni Ayed A Shati Amna A Mohamed Malik Imtinan Al Jabbar Syed E Mahmood Source Type: research
Expanding the allelic spectrum of ELOVL4-related autosomal recessive neuro-ichthyosis
CONCLUSION: Our study expands the allelic spectrum of ELOVL4-related ISQMR. The detection of the same exonic deletion in two unrelated Saudi family from same tribe suggests a tribal founder mutation.PMID:37592902 | DOI:10.1002/mgg3.2256
Source: Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Fatima Alabdulrazzaq Talal Alanzi Haya H Al-Balool Alice Gardham Emma Wakeling Harry G Leitch Moeenaldeen AlSayed Maha Abdulrahim Abdulaziz Aladwani Antonio Romito Kapil Kampe Sacha Ferdinandusse Ashraf H Aboelanine Amira Abdullah Amal Alwadani Laila Bast Source Type: research
Hub genes identification and association of key pathways with hypoxia in cancer cells: A bioinformatics analysis
Saudi J Biol Sci. 2023 Sep;30(9):103752. doi: 10.1016/j.sjbs.2023.103752. Epub 2023 Jul 27.ABSTRACTThree human cancer cell lines (A549, HCT116, and HeLa) were used to investigate the molecular mechanisms and potential prognostic biomarkers associated with hypoxia. We obtained gene expression data from Gene Expression Omnibus (GEO) datasets GSE11704, GSE147384, and GSE38061, which included 5 hypoxic and 8 control samples. Using the GEO2R tool and Venn diagram software, we identified common differentially expressed genes (cDEGs). The cDEGs were then subjected to Gene ontology (GO) and Kyoto Encyclopedia of Gene and Genome (K...
Source: Cancer Control - August 18, 2023 Category: Cancer & Oncology Authors: Faiza Aziz Naila Shoaib Abdul Rehman Source Type: research
Expanding the allelic spectrum of ELOVL4-related autosomal recessive neuro-ichthyosis
CONCLUSION: Our study expands the allelic spectrum of ELOVL4-related ISQMR. The detection of the same exonic deletion in two unrelated Saudi family from same tribe suggests a tribal founder mutation.PMID:37592902 | DOI:10.1002/mgg3.2256
Source: Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Fatima Alabdulrazzaq Talal Alanzi Haya H Al-Balool Alice Gardham Emma Wakeling Harry G Leitch Moeenaldeen AlSayed Maha Abdulrahim Abdulaziz Aladwani Antonio Romito Kapil Kampe Sacha Ferdinandusse Ashraf H Aboelanine Amira Abdullah Amal Alwadani Laila Bast Source Type: research
Genomic characterization of the first mpox and varicella-zoster co-infection in Pakistan (2023) through next-generation sequencing
This study represents the first positive case of MPXV in Pakistan and the coinfection of mpox and VZV by using a metagenome approach providing insights into their complete genomes. Our results highlight the importance of surveillance at the point of entries, strengthening lab capacities including next-generation sequencing, and using differential diagnosis for timely and accurate detection of mpox cases.PMID:37587900 | DOI:10.1002/jmv.29037
Source: Herpes - August 17, 2023 Category: Infectious Diseases Authors: Massab Umair Zunera Jamal Syed A Haider Rabia Hakim Muhammad Ammar Qasim Ali Nasim Akhtar Aamer Ikram Muhammad Salman Source Type: research
Relevance of oil price, military expenditure and exports to achieve the Saudi Arabian sustainable economic and environmental objectives: a non-linear ARDL approach
This study investigates the economic and environmental issues of Saudi Arabia, a net exporter of crude oil mainly relying on oil exports, which faces economic crises due to the decline in oil prices. For this purpose, we highlighted the main challenges of the Saudi economy, such as oil price shocks and a significant increase in military expenditures. The economic and environmental issues are vital for the country's development and sustainability. Saudi Arabia is a major exporter of fossil fuels, which threatens its long-term economic growth due to the global transition towards renewables. Also, heavy dependence on fossil f...
Source: Environmental Science and Pollution Research International - August 17, 2023 Category: Environmental Health Authors: Ghazala Aziz Rida Waheed Source Type: research
Wood-decay fungi associated with decaying of coarse woody debris in Hail Region, North of Saudi Arabia
Cell Mol Biol (Noisy-le-grand). 2023 May 31;69(5):40-43. doi: 10.14715/cmb/2023.69.5.7.ABSTRACTThe present study was conducted in order to describe the assemblage of wood decay fungi and mycomycetes associated with the Hail region in the North of Saudi Arabia by using incubation chambers. There was a collection of coarse woody debris from the study area, AL baithe, which was brought to the laboratory and placed inside a series of incubation chambers in which water was added. Over a period of several weeks, fruiting bodies appeared in these chambers which were morphologically analysed via AmScope stereomicroscope and molecu...
Source: Mol Biol Cell - August 12, 2023 Category: Molecular Biology Authors: None Nawaf Alshammari None Alshammari Bader Fraih Z Mona Saleh Al Tami None Tarun Kumar Upadhyay Source Type: research
Assessment of patient-reported satisfaction and metabolic outcomes following initiation of the second generation of Flash Glucose Monitoring in patients with type 1 diabetes
CONCLUSION: Using second-generation FSL2 in patients with T1D is positively associated with patient-reported satisfaction and metabolic outcomes.PMID:37563819 | DOI:10.2174/1573399820666230810123504
Source: Current Diabetes Reviews - August 11, 2023 Category: Endocrinology Authors: Ayman Abdullah Al Hayek Asirvatham Alwin Robert Wael M Alzahrani Mohamed Abdulaziz Al Dawish Source Type: research
Marine-derived sea urchin compounds as potential anti-cancer drug candidate against colorectal cancer: < em > In silico and in vitro < /em > studies
In this study, 19 compounds derived from sea urchin (Diadema savignyi) were used to treat colorectal cancer using the HCT116 cell line. However, molecular docking, ADME (absorption, distribution, metabolism, and excretion), toxicity, molecular dynamic (MD) simulation, and molecular mechanics generalized Born surface area (MM-GBSA) were used to confirm the ligand-protein interaction. Interactions of Importin-11 receptor with sea urchin compounds reveal that four compounds have higher binding affinities (ranging from -8.6 to -7.1 kcal/mol). In vitro testing revealed that the CID 6432458 compound was effective (docking score ...
Source: Mol Biol Cell - August 10, 2023 Category: Molecular Biology Authors: Mohammad Habibur Rahman Molla Mohammed Othman Aljahdali Source Type: research
Effect of infection with severe acute respiratory syndrome coronavirus 2 on the fetus in pregnant women who recovered from infection
CONCLUSION: Maternal SARS-CoV-2 infection during pregnancy was associated with a higher prevalence of small for gestational age (SGA) fetuses.LIMITATIONS: Retrospective, middle cerebral artery and uterine artery Doppler data were not included nor were the effect of tobacco use and socioeconomic status, the relationship between the date of infection with the date of conceiving or the relationship between the severity of infection in the mother and fetal biometry and growth.CONFLICT OF INTEREST: None.PMID:37554020 | DOI:10.5144/0256-4947.2023.213
Source: Cancer Control - August 9, 2023 Category: Cancer & Oncology Authors: Lina Fahmi Hammad Ahad Naif Almutairi Rana Hussain Aldahlawi Source Type: research
Investigation of the Radiographic Imaging Volume and Occupational Dose of Radiologic Technologists before and during the COVID-19 Pandemic
This study aimed to assess occupational radiation doses for radiologic technologists (RTs) in Saudi Arabia shortly before and during the COVID-19 pandemic, considering changes in imaging volume during that time. This retrospective study included the imaging volume data and the RTs' occupational dose records from a central hospital for 2019 and 2020. The occupational dose-in terms of annual and quarterly mean effective doses (AMEDs and QMEDs)-was estimated for 115 RTs using thermoluminescent dosimeter records. There was a 22% increase in the AMED in 2020 compared with 2019, though the overall imaging volume decreased by 9% ...
Source: Health Physics - August 7, 2023 Category: Physics Authors: Nasser Shubayr Source Type: research
