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Total 14499 results found since Jan 2013.
"Hi, How Can I Help You?" Embracing Artificial Intelligence in Kidney Research
Am J Physiol Renal Physiol. 2023 Aug 17. doi: 10.1152/ajprenal.00177.2023. Online ahead of print.ABSTRACTIn recent years, biology and precision medicine have benefited from the major advancements in generating large-scale molecular and biomedical datasets and in analyzing those data using advanced machine learning algorithms. Machine learning applications in kidney physiology and pathophysiology include segmenting kidney structures from imaging data and predicting conditions like acute kidney injury or chronic kidney disease using electronic health records. Despite the potential of machine learning to revolutionize nephrol...
Source: American Journal of Physiology. Renal Physiology - August 17, 2023 Category: Physiology Authors: Anita T Layton Source Type: research
The ESTHER database on alpha/beta hydrolase fold proteins - An overview of recent developments
Chem Biol Interact. 2023 Aug 13:110671. doi: 10.1016/j.cbi.2023.110671. Online ahead of print.ABSTRACTThe ESTHER database, dedicated to ESTerases and alpha/beta-Hydrolase Enzymes and Relatives (https://bioweb.supagro.inra.fr/ESTHER/general?what=index), offers online access to a continuously updated, sequence-based classification of proteins harboring the alpha/beta hydrolase fold into families and subfamilies. In particular, the database proposes links to the sequences, structures, ligands and huge diversity of functions of these proteins, and to the related literature and other databases. Taking advantage of the promiscui...
Source: Chemico-Biological Interactions - August 15, 2023 Category: Molecular Biology Authors: Arnaud Chatonnet Michel Perochon Eric Velluet Pascale Marchot Source Type: research
Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome
J Clin Endocrinol Metab. 2023 Aug 15:dgad463. doi: 10.1210/clinem/dgad463. Online ahead of print.ABSTRACTSTUDY QUESTION: What is the recommended assessment and management of those with polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertise, and consumer preference?SUMMARY ANSWER: International evidence-based guidelines address prioritized questions and outcomes and include 254 recommendations and practice points, to promote consistent, evidence-based care and improve the experience and health outcomes in PCOS.WHAT IS KNOWN ALREADY: The 2018 International PCOS Guideline was independently ...
Source: The Journal of Clinical Endocrinology and Metabolism - August 14, 2023 Category: Endocrinology Authors: Helena J Teede Chau Thien Tay Joop J E Laven Anuja Dokras Lisa J Moran Terhi T Piltonen Michael F Costello Jacky Boivin Leanne M Redman Jacqueline A Boyle Robert J Norman Aya Mousa Anju E Joham International PCOS Network Source Type: research
The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries
Am J Trop Med Hyg. 2023 Aug 14:tpmd230161. doi: 10.4269/ajtmh.23-0161. Online ahead of print.ABSTRACTThe 2022 global outbreak of human Mpox (formerly monkeypox) virus (MPXV) infection outside of the usual endemic zones in Africa challenged our understanding of the virus's natural history, transmission dynamics, and risk factors. This outbreak has highlighted the need for diagnostics, vaccines, therapeutics, and implementation research, all of which require more substantial investments in equitable collaborative partnerships. Global multidisciplinary networks need to tackle MPXV and other neglected emerging and reemerging z...
Source: Am J Trop Med Hyg - August 14, 2023 Category: Infectious Diseases Authors: Jean B Nachega Placide Mbala-Kingebeni Philip J Rosenthal Anne W Rimoin Nicole A Hoff Laurens Liesenborghs Veerle Vanlerberghe Graciela Andrei Angeli Rawat Lindsay A Wilson Jamie Forrest Edward J Mills Michel P Hermans Sabue Mulangu Francine Ntoumi Alimud Source Type: research
Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome
J Clin Endocrinol Metab. 2023 Aug 15:dgad463. doi: 10.1210/clinem/dgad463. Online ahead of print.ABSTRACTSTUDY QUESTION: What is the recommended assessment and management of those with polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertise, and consumer preference?SUMMARY ANSWER: International evidence-based guidelines address prioritized questions and outcomes and include 254 recommendations and practice points, to promote consistent, evidence-based care and improve the experience and health outcomes in PCOS.WHAT IS KNOWN ALREADY: The 2018 International PCOS Guideline was independently ...
Source: The Journal of Clinical Endocrinology and Metabolism - August 14, 2023 Category: Endocrinology Authors: Helena J Teede Chau Thien Tay Joop J E Laven Anuja Dokras Lisa J Moran Terhi T Piltonen Michael F Costello Jacky Boivin Leanne M Redman Jacqueline A Boyle Robert J Norman Aya Mousa Anju E Joham International PCOS Network Source Type: research
The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries
Am J Trop Med Hyg. 2023 Aug 14:tpmd230161. doi: 10.4269/ajtmh.23-0161. Online ahead of print.ABSTRACTThe 2022 global outbreak of human Mpox (formerly monkeypox) virus (MPXV) infection outside of the usual endemic zones in Africa challenged our understanding of the virus's natural history, transmission dynamics, and risk factors. This outbreak has highlighted the need for diagnostics, vaccines, therapeutics, and implementation research, all of which require more substantial investments in equitable collaborative partnerships. Global multidisciplinary networks need to tackle MPXV and other neglected emerging and reemerging z...
Source: The American Journal of Tropical Medicine and Hygiene - August 14, 2023 Category: Tropical Medicine Authors: Jean B Nachega Placide Mbala-Kingebeni Philip J Rosenthal Anne W Rimoin Nicole A Hoff Laurens Liesenborghs Veerle Vanlerberghe Graciela Andrei Angeli Rawat Lindsay A Wilson Jamie Forrest Edward J Mills Michel P Hermans Sabue Mulangu Francine Ntoumi Alimud Source Type: research
