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Prolonged norovirus infection after pancreas transplantation: a case report and review of chronic norovirus
This article is protected by copyright. All rights reserved. (Source: Transplant Infectious Disease)
Source: Transplant Infectious Disease - October 13, 2015 Category: Transplant Surgery Authors: I.A. Echenique, V. Stosor, L. Gallon, D. Kaufman, C. Qi, T.R. Zembower Tags: Case Report Source Type: research
How to treat a Norovirus infection: Dr Roger explains all about the winter vomiting bug
IT'S known by it's less-attractive name 'the winter vomiting bug' but what do we really know about Norovirus? (Source: Daily Express - Health)
Source: Daily Express - Health - October 9, 2015 Category: Consumer Health News Source Type: news
The impact of calicivirus mixed infection in an oyster-associated outbreak during a food festival
Norovirus (NoV) and sapovirus (SaV) are important viral pathogens of human gastroenteritis in the Caliciviridae family. The low infectious doses  and high environmental persistence  of NoVs lead to efficient multiple-route transmission [3,4] within an outbreak in various epidemiological settings worldwide. The reported calicivirus food-borne outbreaks [5,6,7] indicated that food-borne transmission might occur by contamination from infected food-handlers during processing or during pre-harvesting through contamination with human waste, e.g. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - October 7, 2015 Category: Virology Authors: Yan Wang, Jinan Zhanga, Zhen. Shen Tags: Short Communication Source Type: research
Whole genome sequencing of fecal samples as a tool for the diagnosis and genetic characterization of norovirus
Norovirus is a highly infectious virus with the potential of causing severe gastroenteritis in adults and children. With its unusually low infective dose , norovirus is particularly known for causing hospital outbreaks, necessitating elaborate infection control measures or even ward closure . (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - October 7, 2015 Category: Virology Authors: Herjan H.J. Bavelaar, Janette Rahamat-Langendoen, Hubert G.M. Niesters, Jan Zoll, Willem J.G. Melchers Source Type: research
Comparative Virucidal Efficacy of Seven Disinfectants Against Murine Norovirus and Feline Calicivirus, Surrogates of Human Norovirus
Abstract Human noroviruses (HuNoV) are the leading cause of acute non-bacterial gastroenteritis in humans and can be transmitted either by person-to-person contact or by consumption of contaminated food. A knowledge of an efficient disinfection for both hands and food-contact surfaces is helpful for the food sector and provides precious information for public health. The aim of this study was to evaluate the effect of seven disinfectants belonging to different groups of biocides (alcohol, halogen, oxidizing agents, quaternary ammonium compounds, aldehyde and biguanide) on infectious viral titre and on genomic ...
Source: Food and Environmental Virology - October 7, 2015 Category: Virology Source Type: research
Human Norovirus prevalence in Africa 1990 to 2013
ConclusionUnreported sporadic gastroenteritis cases of Human Norovirus are common in Africa. Most are community‐associated infections. Possible environmental transmission routes have been documented. Combined environmental and clinical studies are required for targeted actions to control transmission of Human Norovirus in Africa. Systematic surveillance of Human Norovirus is needed to measure the burden of Norovirus‐induced gastroenteritis in Africa and support any requirements for vaccine development.This article is protected by copyright. All rights reserved. (Source: Tropical Medicine and International Health)
Source: Tropical Medicine and International Health - October 6, 2015 Category: Tropical Medicine Authors: Jean Pierre Kabue, Emma Meader, Paul Hunter, Natasha Potgieter Tags: Reivew Article Source Type: research
Economic costs of outbreaks of acute viral gastroenteritis due to norovirus in Catalonia (Spain), 2010–2011
Conclusions: The cost of outbreaks of acute viral gastroenteritis due to norovirus obtained in this study was influenced by the number of people affected and the severity of the outbreak, which determined hospitalizations and work absenteeism. Urgent reporting of outbreaks would allow the implementation of control measures that could reduce the numbers affected and the duration of the illness and thus the costs derived from them. (Source: BMC Public Health)
Source: BMC Public Health - October 1, 2015 Category: Consumer Health News Authors: Encarna NavasNuria TornerSonia BronerPere GodoyAna MartínezRosa BartoloméAngela Domínguezthe Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia Source Type: research
No crucial amino acid changes in the predicted Histo Blood Group Antigen binding sites of the Norovirus GII.4 capsid between non-secretors and secretors origin might suggest an alternative route of infection or existence of coincidental molecules.
PMID: 26432289 [PubMed - as supplied by publisher] (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - October 1, 2015 Category: Microbiology Authors: Yoda T, Suzuki Y, Aoyama I, Yamazaki K, Nakata S, Takahashi K Tags: J Med Microbiol Source Type: research
Genotype distribution of norovirus around the emergence of Sydney_2012 and the antigenic drift of contemporary GII.4 epidemic strains
Noroviruses (NoVs) are a leading cause of acute gastroenteritis worldwide. Disease severity is usually moderate, but morbidity and mortality rates due to NoV infection are increasingly becoming evident, with particularly high tolls taken on children and immunocompromised and aged populations [1,2], resulting in an estimated 200,000 deaths per year . GII.4 strains are responsible for >70% of all NoV outbreaks over the past two decades [3,4]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - September 30, 2015 Category: Virology Authors: Jun Zhang, Zhen Shen, Zhaoqin Zhu, Wanju Zhang, Huifen Chen, Fangxing Qian, Haili Chen, Gang Wang, Moying Wang, Yunwen Hu, Zhenghong Yuan Source Type: research
Meeting report: 28th International Conference on Antiviral Research in Rome, Italy.
This article summarizes the principal invited lectures. Phillip Furman, the Elion award recipient, described the research leading to sofosbuvir. Dennis Liotta, who received the Holý award, described how an investigation into HIV entry inhibitors led to a new therapy for cancer patients. Erica Ollmann Saphire, winner of the Prusoff Young Investigator award, explored the world of viral proteins and how they remodel to perform different essential roles in viral replication. The keynote addresses, by Raffaele De Francesco and Michael Manns, reported on the remarkable progress made in the therapy of chronic HCV infections. A t...
Source: Antiviral Research - September 30, 2015 Category: Virology Authors: Vere Hodge RA Tags: Antiviral Res Source Type: research
Determination of cut-off cycle threshold values in routine RT–PCR assays to assist differential diagnosis of norovirus in children hospitalized for acute gastroenteritis
Research Articles N. V. TRANG, M. CHOISY, T. NAKAGOMI, N. T. M. CHINH, Y. H. DOAN, T. YAMASHIRO, J. E. BRYANT, O. NAKAGOMI, D. D. ANH, Epidemiology & Infection, Volume 143 Issue 15, pp 3292-3299Abstract (Source: Epidemiology and Infection)
Source: Epidemiology and Infection - September 29, 2015 Category: Epidemiology Source Type: research
Epidemiology of gastroenteritis viruses in Japan: Prevalence, seasonality, and outbreak
Acute gastroenteritis has been recognized as one of the most common diseases in humans and continues to be a major public health problem worldwide. Several groups of viruses have been reported as the causative agents of acute gastroenteritis, including rotavirus, norovirus, sapovirus, human astrovirus, adenovirus, and an increasing number of others which have been reported more recently. The epidemiology, prevalence, seasonality, and outbreaks of these viruses have been reviewed in a number of studies conducted in Japan over three decades. Rotavirus and norovirus were the two most common viruses detected almost equally in ...
Source: Journal of Medical Virology - September 28, 2015 Category: Virology Authors: Aksara Thongprachum, Pattara Khamrin, Niwat Maneekarn, Satoshi Hayakawa, Hiroshi Ushijima Tags: Review Source Type: research
The efficacy of EO waters on inactivating norovirus and hepatitis A virus in the presence of organic matter
Publication date: March 2016 Source:Food Control, Volume 61 Author(s): Jianlong Fang, Jennifer L. Cannon, Yen-Con Hung The ability of acidic electrolyzed oxidizing water (AEO) and neutral electrolyzed oxidizing water (NEO) to inactivate the murine norovirus (MNV-1) surrogate for human norovirus and hepatitis A virus (HAV) in suspension and on stainless steel coupons in the presence of organic matter was investigated. Viruses containing tryptone (0.0, 0.5, 1.0, 1.5, 2.0, 2.5 and 3.0%) were mixed with AEO and NEO for 1 min. In addition, stainless steel coupons containing MNV-1 with or without organic matter were treate...
Source: Food Control - September 27, 2015 Category: Food Science Source Type: research
A bivalent virus-like particle based vaccine induces a balanced antibody response against both enterovirus 71 and norovirus in mice.
In this study, we investigate the possibility to formulate a VLP-based bivalent vaccine for both norovirus GII.4 and EV71. The GII.4- and EV71-VLPs were produced in a baculovirus-insect cell expression system. A bivalent combination vaccine comprised of GII.4 and EV71 VLPs was formulated and compared with monovalent GII.4- and EV71-VLPs for their immunogenicity in mice. We found that the bivalent vaccine elicited durable antibody responses toward both GII.4 and EV71, and the antibody titers were comparable to that induced by the monovalent vaccines, indicating there is no immunological interference between the two antigens...
Source: Vaccine - September 27, 2015 Category: Allergy & Immunology Authors: Wang X, Ku Z, Dai W, Chen T, Ye X, Zhang C, Zhang Y, Liu Q, Jin X, Huang Z Tags: Vaccine Source Type: research
Alcohol hand rub or soap and water for removal of norovirus from hands – the debate continues
Publication date: Available online 25 September 2015 Source:Journal of Hospital Infection Author(s): J. Steinmann, B. Becker, B. Bischoff, E. Steinmann (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 26, 2015 Category: Infectious Diseases Source Type: research
Erratum for Drouaz et al., Tulane Virus as a Potential Surrogate To Mimic Norovirus Behavior in Oysters.
PMID: 26396178 [PubMed - in process] (Source: Applied and Environmental Microbiology)
Source: Applied and Environmental Microbiology - September 25, 2015 Category: Microbiology Authors: Drouaz N, Schaeffer J, Farkas T, Le Pendu J, Le Guyader FS Tags: Appl Environ Microbiol Source Type: research
Epidemiology of gastroenteritis viruses in Japan: Prevalence, seasonality and outbreak
This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - September 21, 2015 Category: Virology Authors: Aksara Thongprachum, Pattara Khamrin, Niwat Maneekarn, Satoshi Hayakawa, Hiroshi Ushijima Tags: Review Source Type: research
Ginseng, the natural effectual antiviral: Protective effects of Korean red ginseng against viral infection
Publication date: Available online 16 September 2015 Source:Journal of Ginseng Research Author(s): Kyungtaek Im, Jisu Kim, Hyeyoung Min Korean red ginseng (KRG) is a heat-processed ginseng developed by the repeated steaming and air-drying of fresh ginseng. Compared to fresh ginseng, KRG has been shown to possess greater pharmacological activities and stability because of changes that occur in its chemical constituents during the steaming process. In addition to anti-cancer, anti-inflammatory, and immune-modulatory activities, KRG and its purified components have also been shown to possess protective effects against mi...
Source: Journal of Ginseng Research - September 18, 2015 Category: Complementary Medicine Source Type: research
Evaluation of rapid immunochromatographic tests for norovirus in neonatal and infant faecal specimens
Conclusions QN2 offers improved performance and is more useful than QN for the diagnosis of norovirus infection in the neonatal and infant period. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - September 18, 2015 Category: Research Authors: Takahashi, N., Nojima, I., Araki, T., Takasugi, M., Sakane, T., Kodera, A., Ikeda, M., Tsukahara, H. Tags: Research Reports Source Type: research
A Single Nucleotide Polymorphism at the TaqMan Probe-Binding Site Impedes Real-Time Reverse Transcription-PCR-Based Detection of Norovirus GII.4 Sydney [Virology]
A single nucleotide polymorphism (SNP) in the TaqMan probe-binding site resulted in decreased sensitivity of real-time reverse transcription-PCR (RT-rtPCR) for detection of norovirus genogroup II genotype 4 (GII.4) Sydney. A new degenerate probe was designed that improved the sensitivity of the detection while not interfering with the detection of other GII and GI strains. (Source: Journal of Clinical Microbiology)
Source: Journal of Clinical Microbiology - September 16, 2015 Category: Microbiology Authors: Zhuo, R., Hasing, M. E., Team of Molecular Diagnostics, Pang, X. Tags: Virology Source Type: research
Emergence and predominance of norovirus GII.17 in Huzhou, China, 2014–2015
Conclusion: This is the first report of the detection of GII.17 in the Huzhou area and of a NoV genotype being detected in greater numbers than GII.4. Furthermore, our results indicated that following the emergence of GII.17 in October 2014, it steadily replaced the previous circulating GII.4 Sydney2012 strain, which was the dominant circulating genotype for the past 2 years. As norovirus are the important cause of nonbacterial gastroenteritis, continuous and comprehensive study of the norovirus strains involved in large and cost-effective acute gastroenteritis would help understanding the molecular epidemiology of norovi...
Source: Virology Journal - September 11, 2015 Category: Virology Authors: Jiankang HanLei JiYuehua ShenXiaofang WuDeshun XuLiping Chen Source Type: research
Solar water disinfection (SODIS): Impact on hepatitis A virus and on a human Norovirus surrogate under natural solar conditions
This study evaluates the effectiveness of solar water disinfection (SODIS) in the reduction and inactivation of hepatitis A virus (HAV) and of the human Norovirus surrogate, murine Norovirus (MNV-1), under natural solar conditions. Experiments were performed in 330 ml polyethylene terephthalate (PET) bottles containing HAV or MNV-1 contaminated waters (103 PFU/ml) that were exposed to natural sunlight for 2 to 8 h. Parallel experiments under controlled temperature and/or in darkness conditions were also included. Samples were concentrated by electropositive charged filters and analysed by RT-real time PCR (RT-qPCR) and inf...
Source: International Microbiology - September 10, 2015 Category: Microbiology Source Type: research
Characterization and Control of Surfactant-Mediated Norovirus Interactions
Soft Matter, 2015, Accepted ManuscriptDOI: 10.1039/C5SM01778E, PaperBrittany S Mertens, Orlin VelevUnderstanding of the colloidal interactions of Norovirus particles in aqueous medium could provide insights on the origins of the notorious stability and infectivity of these widespread viral agents. We characterized...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Soft Matter latest articles)
Source: RSC - Soft Matter latest articles - September 10, 2015 Category: Chemistry Authors: Brittany S Mertens Source Type: research
Norovirus genotype diversity associated with gastroenteritis outbreaks in aged-care facilities
Brief Report L. D. BRUGGINK, N. L. DUNBAR, J. A. MARSHALL, Epidemiology & Infection, Volume 143 Issue 14, pp 3064-3068Abstract (Source: Epidemiology and Infection)
Source: Epidemiology and Infection - September 9, 2015 Category: Epidemiology Source Type: research
Global Health: Oysters May Serve as Link in Transmission of Norovirus
The shellfish appear to be an important link in the transmission of norovirus among humans, according to research from China. (Source: NYT)
Source: NYT - September 7, 2015 Category: American Health Authors: DONALD G. McNEIL Jr. Tags: Wang, Yongjie Applied and Environmental Microbiology Norovirus Oysters Influenza Food Contamination and Poisoning Source Type: news
Global Health: Oysters May Serve as Link in Transmission of Norovirus
The shellfish appear to be an important link in the transmission of norovirus among humans, according to research from China. (Source: NYT Health)
Source: NYT Health - September 7, 2015 Category: Consumer Health News Authors: DONALD G. McNEIL Jr. Tags: Wang, Yongjie Applied and Environmental Microbiology Norovirus Oysters Influenza Food Contamination and Poisoning Source Type: news
6 Healthy Habits That You Might Be Overdoing
SPECIAL FROM Next Avenue By Linda Melone Taking any action to an extreme — even a healthy one — can have negative consequences. Striving to lose weight becomes unhealthy if it turns into an eating disorder, for example. Exercising until you develop an injury or a serious health issue such as rhabdomyolysis (when muscle tissue breaks down and releases into the blood) can be life-threatening. Other, less extreme, examples can also work against your goal of creating healthier habits and a healthy body. Here are six ways that common, good practices can sometimes work against you: 1. You load up on healthy fa...
Source: Healthy Living - The Huffington Post - September 6, 2015 Category: Consumer Health Advice Source Type: news
Antiviral effects of grape seed extract against feline calicivirus, murine norovirus, and hepatitis A virus in model food systems and under gastric conditions.
The objectives of this study were to determine (1) time and dose-dependence of GSE against FCV-F9, MNV-1, and HAV at room temperature (RT) and 37 °C over 24 h; and (2) GSE effects in model foods (apple juice (AJ) and 2% milk) and simulated gastric conditions at 37 °C. Viruses at ∼5 log PFU/ml were treated with 0.5-8 mg/ml GSE prepared in water, AJ, milk or gastric juices, or water over 24 h at RT or 37 °C. Infectivity of triplicate treatments was evaluated using plaque assays. GSE effects increased with time and concentration. GSE at 1 mg/ml in AJ reduced MNV-1 to undetectable levels after 1 h and by 1 log i...
Source: Food Microbiology - September 5, 2015 Category: Food Science Authors: Joshi SS, Su X, D'Souza DH Tags: Food Microbiol Source Type: research
Evaluation of survival of murine norovirus-1 during sauerkraut fermentation and storage under standard and low-sodium conditions.
Abstract Sodium reduction strategies have raised a few concerns in regards to possible outbreaks in unpasteurised raw fermented vegetables. Among potential outbreak agents, foodborne viruses are recognized as an important cause of food-borne illnesses. As most of them are acid-resistant, evaluation of the efficacy of lactic fermentation in inactivating enteric viruses must be considered to ensure the safety of these foods. In particular with the sodium reduction trend which could impair adequate fermentation in vegetables, we have challenged sauerkraut fermentation at a final concentration of 4 log TCID50/mL with t...
Source: Food Microbiology - September 5, 2015 Category: Food Science Authors: Gagné MJ, Barrette J, Savard T, Brassard J Tags: Food Microbiol Source Type: research
Norovirus P particle: an excellent vaccine platform for antibody production against Alzheimer's disease.
In conclusion, the Norovirus P particle is an excellent vaccine platform for stimulating Aβ42 antibody production, and chimeric P particles may be developed as an effective therapy for AD. PMID: 26349054 [PubMed - as supplied by publisher] (Source: Immunology Letters)
Source: Immunology Letters - September 5, 2015 Category: Allergy & Immunology Authors: Fu L, Li Y, Hu Y, Yu B, Zhang H, Wu J, Wu H, Yu X, Kong W Tags: Immunol Lett Source Type: research
A Probe-free Four-tube Real-Time PCR Assay for Simultaneous Detection of Twelve Enteric Viruses and Bacteria
Conclusion This assay proved to be a cost-effective, sensitive and reliable method for simultaneous detection of enteric viruses and bacteria. (Source: Journal of Microbiological Methods)
Source: Journal of Microbiological Methods - September 4, 2015 Category: Microbiology Source Type: research
Protective role of murine norovirus against Pseudomonas aeruginosa acute pneumonia
Abstract The murine norovirus (MNV) is a recently discovered mouse pathogen, representing the most common contaminant in laboratory mouse colonies. Nevertheless, the effects of MNV infection on biomedical research are still unclear. We tested the hypothesis that MNV infection could alter immune response in mice with acute lung infection. Here we report that co-infection with MNV increases survival of mice with Pseudomonas aeruginosa acute lung injury and decreases in vivo production of pro-inflammatory cytokines. Our results suggest that MNV infection can deeply modify the parameters studied in conventional model...
Source: Veterinary Research - September 4, 2015 Category: Veterinary Research Source Type: research
US regulator reprimands Cepheid for norovirus diagnosis tool quality
Diagnostics firm has 15 days to respond to violations laid out by regulator (Source: Chemistry World | Latest News)
Source: Chemistry World | Latest News - September 4, 2015 Category: Chemistry Authors: Matthew Gunther Source Type: research
Norovirus-Like Illness Sickens at Least 125 Students
Dozens of students were sent home after they started showing symptoms. (Source: ABC News: Health)
Source: ABC News: Health - September 3, 2015 Category: Consumer Health News Tags: Health Source Type: news
Identification of the novel Kawasaki 2014 GII.17 human norovirus strain in Italy, 2015
Surveillance of noroviruses in Italy identified the novel GII.17 human norovirus strain, Kawasaki 2014, in February 2015. This novel strain emerged as a major cause of gastroenteritis in Asia during 2014/15, replacing the pandemic GII.4 norovirus strain Sydney 2012, but being reported only sporadically elsewhere. This novel strain is undergoing fast diversification and continuous monitoring is important to understand the evolution of noroviruses and to implement the future strategies on norovirus vaccines. (Source: Eurosurveillance)
Source: Eurosurveillance - September 3, 2015 Category: Infectious Diseases Source Type: research
Analysis of norovirus outbreaks reveals the need for timely and extended microbiological testing
Conclusion Future prevention strategies should focus not only on patients but also on staff. Constant surveillance for new cases of diarrhoea and vomiting and timely adherence to contact precautions for all exposed persons is crucial in outbreak control, as is the need for extended microbiological testing. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - September 3, 2015 Category: Infectious Diseases Source Type: research
Adoption of a microbial health-based target for Australian drinking water regulation.
Authors: O'Toole J, Sinclair M, Gibney K, Leder K Abstract The health-based targets of 1 in 10,000 for infection and 10(-6) disability adjusted life years (DALYs) per person per year are increasingly being considered, or have already been adopted, to define microbial safety targets for water. The aim of this paper is to convey information about how these two targets compare by converting each of the target values to a common metric. The metric chosen for viral (rotavirus and norovirus) and protozoan (Cryptosporidium) reference pathogens is the estimated maximum number of annual drinking water-associated cases of ac...
Source: Journal of Water and Health - September 1, 2015 Category: Environmental Health Tags: J Water Health Source Type: research
Early occurrence of Influenza A epidemics coincided with changes in occurrence of other respiratory virus infections
ConclusionWhen influenza A epidemics occured early, timing of the epidemics of several respiratory winter viruses usually occuring close in time to influenza A was affected while trends in rhinoviruses (occurring in autumn) and trends in enteral viruses were not.This article is protected by copyright. All rights reserved. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - September 1, 2015 Category: Virology Authors: Liselotte Asten, Paul Bijkerk, Ewout Fanoy, Annemarijn Ginkel, Anita Suijkerbuijk, Wim Hoek, Adam Meijer, Harry Vennema Tags: Original Article Source Type: research
Diagnosis and Management of Foodborne Illness.
Abstract The Centers for Disease Control and Prevention estimates that each year, one in six Americans will experience a foodborne illness. The most common causes in the United States are viruses, such as norovirus; bacteria, such as Salmonella, Escherichia coli, Campylobacter, and Listeria; and parasites, such as Toxoplasma gondii and Giardia. Resources are available to educate consumers on food recalls and proper handling, storage, and cooking of foods. Diagnosis and management of a foodborne illness are based on the history and physical examination. Common symptoms of foodborne illnesses include vomiting, diarrh...
Source: American Family Physician - September 1, 2015 Category: Primary Care Authors: Switaj TL, Winter KJ, Christensen SR Tags: Am Fam Physician Source Type: research
Cytomegalovirus and other common enteric viruses are not commonly associated with NEC
ConclusionAlthough case reports indicate an episodic association of enteric viruses in NEC, the inability to detect any of these viruses in our 17 NEC infants suggests that a viral aetiology is unlikely to be causative for most sporadic forms of NEC. (Source: Acta Paediatrica)
Source: Acta Paediatrica - August 31, 2015 Category: Pediatrics Authors: Thomas Skeath, Christopher Stewart, Sheila Waugh, Nicholas Embleton, Stephen Cummings, Janet Berrington Tags: Regular Article Source Type: research
Inactivation of murine norovirus-1 and hepatitis A virus on fresh meats by atmospheric pressure plasma jets
Publication date: October 2015 Source:Food Research International, Volume 76, Part 3 Author(s): San-Cheong Bae, Shin Young Park, Wonho Choe, Sang-Do Ha In the current study, inactivation effect of atmospheric pressure plasma (APP) jets (10s–20min) was investigated against murine norovirus (MNV-1), as a norovirus (NoV) surrogate and hepatitis A virus (HAV) associated with three types of fresh meats (beef loin, pork shoulder and chicken breast). The quality characteristics of fresh meats, such as surface color, moisture content and thiobarbituric acid reactive substance (TBARS) were also examined. After 5–20min of ...
Source: Food Research International - August 31, 2015 Category: Food Science Source Type: research
A Synergistic Effect of Trisodium Phosphate and Ethanol on the Inactivation of Murine Norovirus 1 on Lettuce and Bell peppers.
Abstract The synergy effect of trisodium phosphate (TSP) and ethanol against murine norovirus 1 (MNV-1) as a surrogate for human noroviruses on fresh produces was evaluated. More than 2% (W/V) of TSP effectively inactivated MNV-1. The single treatment of 1% TSP or 30% ethanol for 30 min was not effective on MNV-1, however, cotreatment showed inactivation of MNV-1 on stainless steel and the produces of lettuce and bell pepper under 15 min. The results suggest that cotreatment of TSP and ethanol with the low concentration and at a short time exposure might be useful for reduction of norovirus in some produces. PM...
Source: Journal of Microbiology and Biotechnology - August 31, 2015 Category: Biotechnology Authors: Kim EJ, Lee YD, Kim KY, Park JH Tags: J Microbiol Biotechnol Source Type: research
Application of Luminex Gastrointestinal Pathogen Panel to human stool samples from Côte d’Ivoire
Conclusions: Considering the burden of enteric infections in developing countries, particularly among children, and the high rate of co-infections in asymptomatic subjects, this study shows the need for diagnostic tools such as xTAG GPP to improve diagnosis and treatment of these infections in endemic areas. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 29, 2015 Category: Infectious Diseases Source Type: research
Tropical and travel-associated norovirus: current concepts
Purpose of review: We highlight recent advances relevant to understanding norovirus infections in the tropics, both in populations living in developing settings and travelers to these regions. Recent findings: Because of the decrease in diarrheal disease associated with the global rollout of vaccines against rotavirus, norovirus is emerging as the predominant cause of diarrhea morbidity among children in the tropics, and evidence suggests that it contributes to adult disease in endemic populations and travelers. In addition to identifying potential target populations for preventive measures, we provide an update on norovir...
Source: Current Opinion in Infectious Diseases - August 29, 2015 Category: Infectious Diseases Tags: TROPICAL AND TRAVEL-ASSOCIATED DISEASES: Edited by Joseph M. Vinetz and Yukari C. Manabe Source Type: research
Comparative Evaluation of Broad-Panel PCR Assays for the Detection of Gastrointestinal Pathogens in Pediatric Oncology Patients
Publication date: Available online 29 August 2015 Source:The Journal of Molecular Diagnostics Author(s): Zhengming Gu, Haiqing Zhu, Alicia Rodriguez, Mohammad Mhaissen, Stacey Schultz-Cherry, Elisabeth Adderson, Randall T. Hayden Broadly multiplexed molecular amplification assays offer an unprecedented ability to diagnose gastrointestinal infection in immunocompromised patients. However, little data are available to compare the performance of such systems in this population. A total of 436 stool samples were collected from 199 patients, predominantly immunocompromised pediatric oncology patients. Remnant samples w...
Source: The Journal of Molecular Diagnostics - August 29, 2015 Category: Pathology Source Type: research
Eating raw oysters carries risk of human norovirus
Stephen FellerSHANGHAI, Aug. 28 (UPI) -- Researchers found that many of the world's strains of human norovirus can be found in oysters, and suggest that people not eat them raw to prevent infection. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 28, 2015 Category: Consumer Health News Source Type: news
Oysters harbor, transmit human norovirus: Avoid raw ones
Oysters not only transmit human norovirus; they also serve as a major reservoir for these pathogens, according to newresearch. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 28, 2015 Category: Science Source Type: news
Oysters harbor, transmit human norovirus: Avoid raw ones
(American Society for Microbiology) Oysters not only transmit human norovirus; they also serve as a major reservoir for these pathogens, according to research published Aug. 28 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 28, 2015 Category: Infectious Diseases Source Type: news
Rapid, simple and efficient method for detection of viral genomes on raspberries.
In this study, an alternative method of extraction in which RNAs are directly extracted from food matrices (based on direct RNA extraction) has been optimized. First, each step was improved to make it a highly rapid, specific and simple method. Second, the standard virus concentration method was compared with the optimized direct RNA extraction one. Human enteric viral surrogates, Murine Norovirus (MNV) and F-specific RNA bacteriophage GA, were selected according to their adhesion properties and resistance to pH close to our main targets (NoV and HAV). Raspberries were artificially contaminated using two different techniqu...
Source: Journal of Virological Methods - August 28, 2015 Category: Virology Authors: Perrin A, Loutreul J, Boudaud N, Bertrand I, Gantzer C Tags: J Virol Methods Source Type: research