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This page shows you the latest news and research items in this category.

Changing pattern of antibiotic resistance of Helicobacter pylori in children during 20 years in Jinju, South Korea
ConclusionsThe antibiotic resistance rates of H. pylori in Jinju had a different pattern to other regions. The antibiotic resistance rates of H. pylori showed geographic variation, and local data should be provided as a guideline for treating H. pylori infection. (Source: Pediatrics International)
Source: Pediatrics International - June 18, 2013 Category: Pediatrics Authors: Ji‐Hyun Seo, Jin‐Su Jun, Jung Sook Yeom, Ji Sook Park, Hee‐Shang Youn, Gyung‐Hyuck Ko, Seung‐Chul Baik, Woo‐Kon Lee, Myung‐Je Cho, Kwang‐Ho Rhee Tags: ORIGINAL ARTICLE Source Type: research

Endoscopy in the diagnosis of intestinal graft‐versus‐host disease: Is lower endoscopy with biopsy as effective in diagnosis as upper endoscopy combined with lower endoscopy?
ConclusionUse of sigmoid biopsy for GvHD diagnosis is effective, safe, and less expensive compared to other endoscopic interventions. Pediatr Blood Cancer 2013;9999:XX–XX. © 2013 Wiley Periodicals, Inc. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - June 15, 2013 Category: Cancer & Oncology Authors: Kody R. Crowell, Raza A. Patel, Mark Fluchel, Amy Lowichik, Staci Bryson, John F. Pohl Tags: Research Article Source Type: research

Diversity of endoscopy center operations and practice variation across California's safety-net hospital system: a statewide survey
Conclusion: Our study highlights the diversity and practice variations of endoscopy center operations at California public hospitals and serves as a catalyst for future collaborations among safety-net hospitals. (Source: BMC Research Notes)
Source: BMC Research Notes - June 15, 2013 Category: Research Authors: Lukejohn DayTaft BhuketJohn InadomiHal Yee Source Type: research

Methemoglobinemia in Patients Undergoing Esophagogastroduodenoscopy: A Randomized Controlled Trial
(Source: Military Medicine)
Source: Military Medicine - June 12, 2013 Category: Global & Universal Authors: Hall, Noah M.Jones, Frances J.Ainsworth, Craig R.Fincher, R. Keith Tags: Articles Source Type: research

The Basics of Hiatal Hernias
A hiatal hernia occurs when the upper part of the stomach pushes through an opening in the diaphragm, and up into the chest. This opening is called a esophageal hiatus or diaphragmatic hiatus. Approximately 50 percent of hiatal hernia patients don't experience any symptoms. For the other 50 percent of patients, the these hiatal hernia symptoms may occur. There are a number of contributing factors that can cause hiatal hernias. While some patients with a hernia hernia may also have GERD, GERD doesn't cause a hiatal hernia. Various tests can be used to diagnose a hiatal hernia, though the tests most often used are the bar...
Source: About Heartburn / Acid Reflux - June 10, 2013 Category: Consumer Health Advice Source Type: news

The Basics of Peptic Ulcers
Peptic ulcers can cause a variety of symptoms, and these vary from patient to patient. Some patients with ulcers have minimal, unusual, or even no symptoms at all. Others may have every symptom. This is why it is very important to consult your doctor if you have any concerns. It is important to understand the causes of peptic ulcers. In the past, it was believed stress and diet caused peptic ulcers. Later, researchers stated stomach acids (hydrochloric acid and pepsin) contributed to the majority of ulcer formation. Today, however, research shows that most ulcers develop as a result of infection with a bacterium called ...
Source: About Heartburn / Acid Reflux - June 10, 2013 Category: Consumer Health Advice Source Type: news

Scalloping is a reliable endoscopic marker for celiac disease
ConclusionThe results suggest that the diagnosis of CD is almost certain if isolated scalloping is observed during EGD done to rule out CD. Thus, attention to this finding may serve as an additional tool in the diagnosis of CD. (Source: Digestive Endoscopy)
Source: Digestive Endoscopy - June 9, 2013 Category: Gastroenterology Authors: Yair Kasirer, Dan Turner, Leora Lerman, Abraham Schechter, Jacob Waxman, Bosmat Dayan, Ari Bergwerk, Yelena Rachman, Zerem Freier, Ari Silbermintz Tags: Original Article Source Type: research

Laparoscopic findings of congenital hepatic fibrosis: a case report and review of the literature
Abstract A 33‐year‐old man visited a hospital after vomiting blood. Emergent esophagogastroduodenoscopy revealed the presence of varices in the lower esophagus. The patient did not have a past history of alcohol consumption and was negative for hepatitis B and C viruses. He was referred to our hospital for closer examination. Portal hypertension was detected by conventional imaging modalities, but signs of liver cirrhosis, thrombosis, stenosis, malformation of the portal vein, and bile duct abnormalities were not observed. We performed laparoscopy‐guided liver biopsy to examine the cause of portal hypertension. In ad...
Source: Hepatology Research - June 1, 2013 Category: Internal Medicine Authors: Michiharu Komatsu, Naoki Tanaka, So‐ichirou Shibata, Takefumi Kimura, Yuki Ichikawa, Susumu Morita, Satoru Joshita, Tadanobu Nagaya, Takeji Umemura, Tetsuya Ichijo, Akihiro Matsumoto, Kaname Yoshizawa, Eiji Tanaka Tags: Case Report Source Type: research

Gastric Cancer Mortality in a High Incidence Area: Long-term follow-up of Helicobacter pylori-related Precancerous Lesions in the General Population.
CONCLUSIONS: In this population with a high rate of H. pylori infection, age over 50 years, smoking, family history of GC, IM, AG, and in particular, an undiagnosed GU were significant independent risk factors for mortality due to GC. The assessment of a combination of these risk factors might identify individuals at risk of GC who could possibly benefit from regular surveillance. PMID: 23725067 [PubMed - in process] (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - June 1, 2013 Category: Middle East Health Authors: Boreiri M, Samadi F, Etemadi A, Babaei M, Ahmadi E, Sharifi AH, Nikmanesh A, Houshiar A, Pourfarzai F, Yazdanbod A, Alimohammadian M, Sotoudeh M Tags: Arch Iran Med Source Type: research

Crohn's Disease Presenting as a Neutrophilic Dermatosis in a 5‐Month‐Old Boy
Abstract A 5‐month‐old boy with a previous history of failure to thrive and poor feeding was admitted to the hospital with failure to thrive, oral ulcers, and a generalized vesiculopustular rash that demonstrated a subcorneal pustule and neutrophilic infiltrate on histology. Esophagogastroduodenoscopy and flexible sigmoidoscopy biopsies demonstrated chronic active colitis with granulomas, consistent with the diagnosis of Crohn's disease. Our case represents, to our knowledge, the youngest person reported with this condition in association with Crohn's disease. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 31, 2013 Category: Dermatology Authors: Angela M. Sutton, Hillary S. Lawrence, Kristi M. Canty Tags: Case Report Source Type: research

Transoral robotic approach to carcinoma of unknown primary
Conclusions. Together with panendoscopy, directed biopsies and PET/CT, TORS is a valuable option in the identification and treatment of primary tumor sites. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)
Source: Head and Neck - May 29, 2013 Category: ENT & OMF Authors: Kasim Durmus, Sanjeet V. Rangarajan, Matthew O. Old, Amit Agrawal, Theodoros N. Teknos, Enver Ozer Tags: Original Article Source Type: research

Natural history of acute upper GI bleeding due to tumours: short‐term success and long‐term recurrence with or without endoscopic therapy
ConclusionsPatients presenting with tumour‐associated UGIB have substantial blood loss, with three‐quarters requiring transfusion at presentation. Initial haemostasis occurs in almost all patients, with or without endoscopic therapy, but rebleeding requiring repeat hospitalisation occurs in approximately half the patients and is more common in patients who are ≤60 years of age and have haemodynamic instability at presentation. (Source: Alimentary Pharmacology and Therapeutics)
Source: Alimentary Pharmacology and Therapeutics - May 28, 2013 Category: Drugs & Pharmacology Authors: S. Sheibani, J. J. Kim, B. Chen, S. Park, B. Saberi, K. Keyashian, J. Buxbaum, L. Laine Tags: Original Article Source Type: research

Capsule vs Conventional Endoscopy for Heartburn, DyspepsiaCapsule vs Conventional Endoscopy for Heartburn, Dyspepsia
Is conventional upper endoscopy as effective as capsule endoscopy in the assessment of both heartburn and dyspepsia? This new study compares the 2 procedures. Frontline Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 28, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Summary of evidence-based guideline: Periprocedural management of antithrombotic medications in patients with ischemic cerebrovascular disease: Report of the Guideline Development Subcommittee of the American Academy of Neurology
Objective: To assess evidence regarding periprocedural management of antithrombotic drugs in patients with ischemic cerebrovascular disease. The complete guideline on which this summary is based is available as an online data supplement to this article. Methods: Systematic literature review with practice recommendations. Results and recommendations: Clinicians managing antithrombotic medications periprocedurally must weigh bleeding risks from drug continuation against thromboembolic risks from discontinuation. Stroke patients undergoing dental procedures should routinely continue aspirin (Level A). Stroke patients underg...
Source: Neurology - May 27, 2013 Category: Neurology Authors: Armstrong, M. J., Gronseth, G., Anderson, D. C., Biller, J., Cucchiara, B., Dafer, R., Goldstein, L. B., Schneck, M., Messe, S. R. Tags: Ultrasound, All Medical/Systemic disease, All Neuro-ophthalmology, All Cerebrovascular disease/Stroke, All Trauma SPECIAL ARTICLE Source Type: research

A Mysterious Case of Dysphagia Demystified by Medication Reconciliation
A 77-year-old woman was referred to the Cleveland Clinic Foundation with symptoms of acute-onset but persistent dysphagia, odynophagia, and a 15-pound weight loss during the previous 8 weeks. She had no significant medical or surgical history. Her only medications were zolpidem. She denied taking any over-the-counter medications. Computed tomography scan of the chest showed thickening of the proximal esophagus. Esophagogastroduodenoscopy showed a small focal area of inflammation at the upper esophagus, and biopsy showed some ulcerated granulation tissue with acute inflammation and negative for fungi. She was discharged wit...
Source: The American Journal of Medicine - May 24, 2013 Category: Journals (General) Authors: Karthik Ragunathan, Prabhleen Chahal Tags: Clinical communications to the editor Source Type: research

A Rome III survey of functional dyspepsia among the ethnic Malays in a primary care setting
Conclusions: FD was more common than one had expected among Malays attending primary care clinic in an area with low prevalence of H. pylori. (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - May 14, 2013 Category: Gastroenterology Authors: Yeong LeeNoriza WahabNazri MustaffaNorwati DaudNoorhayati Mohd NoorJuwita ShaabanAndrew Chua Source Type: research

Barrett's esophagus and the risk of obstructive sleep apnea: a case--control study
Conclusions: In this pilot study, a high proportion of Barrett's esophagus subjects scored at high risk for obstructive sleep apnea. Having Barrett's esophagus was associated with more severe gastroesophageal reflux symptoms, and nocturnal reflux symptoms were associated with scoring at high risk for obstructive sleep apnea. The need for obstructive sleep apnea screening in Barrett's esophagus patients with nocturnal gastroesophageal reflux symptoms should be further evaluated. (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - May 11, 2013 Category: Gastroenterology Authors: Linda CummingsNinad ShahSanto MaimoneWajeeh SalahVijay KhianiAmitabh Chak Source Type: research

Pilot study: miscellaneous therapy is highly successful for Helicobacter pylori eradication
ConclusionA miscellaneous therapy, based on the combination of multiple medications in high doses for 2 weeks, and with gastric PH elevation, is a highly effective treatment as a first‐line therapy for the eradication of H. pylori. (Source: Alimentary Pharmacology and Therapeutics)
Source: Alimentary Pharmacology and Therapeutics - May 8, 2013 Category: Drugs & Pharmacology Authors: F. Sierra, J. D. Forero, M. Rey, M. L. Botero, A. Cárdenas Tags: Original Article Source Type: research

When dermatology meets gastroenterology: a case of odynophagia
Clinical presentation A 60-year-old woman with a long standing history of cutaneous pemphigus vulgaris (PV), was admitted to our hospital complaining of progressive dysphagia and odynophagia to both liquids and solids over a 2-month duration. Patient suffered from limited oral caloric intake and a 30-pound weight loss. Current medication included oral Prednisone and recently started Azathioprine. On physical examination, she had multiple denuded hyperaemic lesions involving soft palate, gingiva, uvula, and oropharynx. Numerous hyperpigmented cutaneous macules and crusted erosions in different stages of healing were appreci...
Source: Gut - April 30, 2013 Category: Gastroenterology Authors: Gurvits, G. E. Tags: GUT Snapshot Editor ' s quiz: GI snapshot Source Type: research

Cramping Pain and Eosinophilic Ascites: What Is the Diagnosis?
Question: A 37-year-old woman presented with a 15-day cramping, diffuse abdominal pain, and increased abdominal size without diarrhea, vomiting, or respiratory or urinary symptoms. Physical examination revealed distended abdomen, slightly painful, with shifting dullness present. She had no fever, rash, or adenopathy. Initial laboratory tests showed leukocytosis (17,000/μL), eosinophilia (2330/μL), C-reactive protein 2.5 times the upper limit of normal, and normal serum albumin (3.58 g/dL). The patient underwent abdominal computed tomography that revealed moderate volume ascites and diffuse thickening of the small bowel (...
Source: Gastroenterology - April 29, 2013 Category: Gastroenterology Authors: Paulo Salgueiro, Ricardo Magalhães, Paula Lago Tags: Clinical Challenges and Images in GI Source Type: research

Severe Abdominal Pain 2 Days After Endoscopic Treatment
Question: A 47-year-old man with a history of decompensated liver cirrhosis was admitted to our hospital owing to the passage of tarry stools for 3 days. The esophagogastroduodenoscopy (EGD) showed a duodenal ulcer with a visible, nonbleeding vessel (). Endoscopic hemostasis was achieved by clipping the vessel and injection of epinephrine (12 mL, 0.2%; ). Two days later, the patient developed progressive abdominal pain accompanied by nausea, vomiting, and cold sweating. At that time, physical examination revealed tenderness in the epigastric area without muscle rigidity or rebound pain. Laboratory studies revealed anemia (...
Source: Gastroenterology - April 29, 2013 Category: Gastroenterology Authors: Ping-Hung Ko, Tsung-Hsing Hung, Chih-Wei Tseng Tags: Clinical Challenges and Images in GI Source Type: research

Now You See It, Endo You Don't: Case of the Disappearing Knife
Question: A 32-year-old woman with a psychiatric history of compulsive foreign body ingestions resulting in multiple upper endoscopies and retrievals, presented to the emergency room after swallowing a butter knife approximately 10 hours earlier. Chief symptoms included an inability to rotate her neck, odynophagia, and chest pain. Vital signs revealed an afebrile normotensive patient with a heart rate of 140 bpm. Physical examination of her oropharynx revealed no gross lesions or signs of trauma, crepitus, or palpable mass in the neck. Abdominal examination was unrevealing for epigastric tenderness, rebound, or guarding. L...
Source: Gastroenterology - April 29, 2013 Category: Gastroenterology Authors: Sean Fine, James B. Watson, Fadlallah Habr Tags: Electronic Clinical Challenges and Images in GI Source Type: research

Recurrent Digital Petechiae and Weight Loss in a Young Adult
Question: A 38-year-old Caucasian man with no relevant medical history presented to the dermatology department with a 7-month history of recurrent petechiae on the fingers. Anteceding trauma or repetitive pressure were denied. The patient reported occasional local discomfort in the form of stinging pain. The patient also reported a 5-kg weight loss over the past 3 months. He was otherwise in a good health status. Physical examination disclosed several reddish–brown, hemorrhagic maculae on the volar and lateral aspects of the fingertips (). The rest of the physical examination was unremarkable. Laboratory studies, includi...
Source: Gastroenterology - April 29, 2013 Category: Gastroenterology Authors: Daniel López Aventín, Lucas Ilzarbe, Josep E. Herrero-González Tags: Electronic Clinical Challenges and Images in GI Source Type: research

[A case of angiographic embolization of aortoenteric fistula caused by endovascular stent grafting for an abdominal aortic aneurysm].
We report a rare case of AEF bleeding after endovascular stent grafting for AAA which was managed angiographically. An 81-year-old man presented with hematochezia and acute abdominal pain for 1 day ago. Four years ago, an aortic stent was implanted in the infrarenal aorta for AAA. Endoscopies were performed to evaluate the hematochezia. Evidence of gastrointestinal bleeding was observed, but a clear bleeding point was not detected on upper endoscopy and colonoscopy. Contrast-enhanced computed tomography performed subsequently showed that the bleeding point was located in the fourth portion of the duodenum as an AEF caused ...
Source: Korean J Gastroenter... - April 25, 2013 Category: Gastroenterology Authors: Ko KH, Kim SY, Jung IS, Kim KS, Moon HS, Seong JK, Jeong HY Tags: Korean J Gastroenterol Source Type: research

Unusual intussusception within a hiatal hernia sac, reduced endoscopically
A 70-year-old man was admitted with acute dysphagia to solids and liquids. He had a history of gastroesophageal reflux disease, Barrett's esophagus, and large hiatal hernia, and he had previously undergone three antireflux surgical procedures, including a Nissen fundoplication, and then two repeated operations, the first through a left thoracoabdominal approach and the second through a right thoracotomy. His most recent endoscopy, performed for surveillance of Barrett's esophagus 2 months before admission, showed long segment Barrett's esophagus, a hiatal hernia with patent hiatal narrowing () and large gastric wrap folds ...
Source: Gastrointestinal Endoscopy - April 13, 2013 Category: Gastroenterology Authors: Ihab I. El Hajj, Lei Y. Lim, Leticia P. Luz, Nabil F. Fayad Tags: At the Focal Point Source Type: research

Transparent Cap Assisted Endoscopic Management of Foreign Bodies in the Upper Esophagus: A randomized controlled trial
ConclusionsTransparent cap‐assisted endoscopy was a safe and effective method in the management of FBs in the upper esophagus, with a shorter operation time and clearer visual field. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - April 11, 2013 Category: Gastroenterology Authors: Shenghong Zhang, Jinhui Wang, Jinping Wang, Bihui Zhong, Minhu Chen, Yi Cui Tags: Clinical Gastroenterology Source Type: research

Prevalence of Helicobacter pylori in a First Nations population in northwestern Ontario.
CONCLUSION: This study raises the clinical question of how eradication testing and treatment protocols should be addressed in remote regions with high disease prevalence. As more is learned about the role H pylori infection plays in serious gastrointestinal diseases, rural and aboriginal populations might need a special focus on testing availability and treatment close to home. PMID: 23585621 [PubMed - in process] (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 1, 2013 Category: Primary Care Authors: Sethi A, Chaudhuri M, Kelly L, Hopman W Tags: Can Fam Physician Source Type: research

Gastroesophageal Reflux Disease Questionnaire (GerdQ) in real‐world practice: A national multicenter survey on 8065 patients
ConclusionsThe study suggests the proportions of Chinese patients with reflux esophagitis rise up with the increase of GerdQ score, and GerdQ may be used for diagnosis of GERD. However, low GerdQ score cannot exclude the possibility of reflux esophagitis. A minority of Chinese patients has high GerdQ score but is diagnosed with malignancies, even in the absence of alarm features. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - March 25, 2013 Category: Gastroenterology Authors: Yu Bai, Yiqi Du, Duowu Zou, Zhendong Jin, Xianbao Zhan, Zhao‐Shen Li, Yunsheng Yang, Yulan Liu, Shutian Zhang, Jiaming Qian, Liya Zhou, Jianyu Hao, Dongfeng Chen, Dianchun Fang, Daiming Fan, Xiaofeng Yu, Weihong Sha, Yuqiang Nie, Xiaofeng Zhang, Hong Xu Tags: Gastroenterology Source Type: research

Covering the Cover
Gluten-free diets are recommended with increasing frequency for irritable bowel syndrome (IBS) symptoms in the absence of celiac disease. Patients who do not have celiac disease, but possess a consistent genotype of HLA DQ2/8, have also reported benefit from a gluten-free diet. In this issue of Gastroenterology, Vazquez–Roque et al report on a randomized, controlled trial designed to explore whether a gluten-free diet benefits patients with diarrhea-predominant IBS (IBS-D). The study was performed at the Mayo Clinic where 45 patients with known IBS-D were recruited. The patients were divided into 2 groups, one ingesting ...
Source: Gastroenterology - March 25, 2013 Category: Gastroenterology Authors: Anson W. Lowe, Richard H. Moseley Tags: Covering the Cover Source Type: research

Spleen Stiffness: The New Kid on the Block for Diagnosing Portal Hypertension?
We would like to congratulate Takuma et al for presenting their remarkable data on using spleen stiffness measured by acoustic radiation force impulse (ARFI) as a sensitive predictor of esophageal varices in cirrhosis. This work is important and evidence that we continue to embrace the concept of primum non nocere in clinical practice, from invasive diagnostics (intraoperative direct measurement of portal pressure) to minimally invasive (hepatic venous pressure gradient measurement and esophagogastroduodenoscopy [EGD]) and now noninvasive techniques (spleen stiffness by ultrasound-based elastography). (Source: Gastroenterology)
Source: Gastroenterology - March 25, 2013 Category: Gastroenterology Authors: Jun Liong Chin, Grace Chan, P. Aiden McCormick Tags: Correspondence Source Type: research

Duodenal lipomatosis
A 54-year-old man with a history of tonsillar cancer had a follow-up CT scan, which showed incidental duodenal lipomatosis (). Two years later, upper endoscopy was performed to evaluate acid reflux. A small hiatus hernia was observed. Starting at the distal end of the bulb and leading to the third part of the duodenum were 10 submucosal lesions 0.5 to 2.0 cm in diameter (). Probing with the forceps resulted in a shallow pillow sign, and biopsies of three nodules resulted in exposure of underlying fat (). Pathologic examination revealed typical findings of a submucosal lipoma. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - March 25, 2013 Category: Gastroenterology Authors: Leonard B. Weinstock, Jan Axelbaum, Emily Norman Tags: At the Focal Point Source Type: research

Endoscopic removal of a bullet after mediastinum gunshot injury
A 39-year-old policeman was admitted to our emergency department with a thoracic gunshot injury. His only symptom was local pain, without dyspnea, hemoptysis, or hematemesis. On physical examination, a bullet entry wound was seen in the left midclavicular line, and no exit wound or subcutaneous emphysema was identified. Angiotomography showed the bullet lodged at the T1-T2 level, without vascular lesions. An esophagogram revealed the bullet in the upper mediastinum, causing deviation of the esophagus without extravasation of contrast medium. Upper endoscopy demonstrated an elevated area with a small fistulous orifice ( arr...
Source: Gastrointestinal Endoscopy - March 25, 2013 Category: Gastroenterology Authors: Cristiane Kibune Nagasako, Ciro Garcia Montes, Luiz Roberto Lopes, Marina da Silveira Bossi, Maria Aparecida Mesquita Tags: At the Focal Point Source Type: research

Esophageal Perforation Caused by Mycobacterium tuberculosis
A 37-year-old man presented from prison with a 1-month history of fever, abdominal distension, and weight loss. Prison personnel reported that he may have ingested a foreign body. Computed tomography of the abdomen and pelvis revealed massive, loculated abdominal ascites and peritoneal enhancement. Computed tomography of the thorax showed multiple centrinodular lung lesions and a subcarinal, paraesophageal mixed gas and soft tissue density with focal pneumomediastinum, indicating esophageal perforation. A purified protein derivative test performed in the hospital showed negative results. The patient had no history of liver...
Source: The American Journal of Medicine - March 18, 2013 Category: Journals (General) Authors: Joseph G. Baltz, Andrew S. Brock Tags: Clinical communications to the editor Source Type: research

Successful Atrioesophageal Fistula Repair After Atrial Fibrillation Ablation
A 50-year-old woman with chronic kidney disease and rheumatoid arthritis underwent radiofrequency catheter ablation for symptomatic persistent atrial fibrillation. The patient sought treatment at the emergency room after 4 weeks with minor hematemesis. Esophagogastroduodenoscopy revealed a thrombus along the esophageal wall (A). Computed tomography scans of the chest demonstrated abnormal contouring of the left atrial wall, concerning for atrioesophageal fistula and pleural effusions (B and C, red arrow). Emergency cardiac and esophageal surgery was performed, during which the left atrium was repaired via a pericardial pat...
Source: Journal of the American College of Cardiology - March 15, 2013 Category: Cardiology Authors: Giovanni A. Rivera, Irving B. David, Rishi G. Anand Tags: IMAGES IN CARDIOLOGY Source Type: research

Role of Endoscopic Ultrasonography in Patients With Thickened Wall Stomach by CT Scan
The usefulness of endoscopic ultrasonography (EUS) in patients who have gastric wall thickening in computed tomography (CT) is not clear. All patients referred for EUS due to thickened gastric folds on CT were included in this study. Esophagogastroduodenoscopy (EGD) followed by EUS was performed on all patients. Twenty-eight patients were enrolled in the study. The mean ± SD age was 50.8 ± 15.9 years, and 60.7% were male. Most patients (78.6%) had symptoms, and 10 patients (35.7%) were ultimately diagnosed with a gastric neoplasm. In all patients with a normal EGD (11 patients), the EUS was normal. Accuracy, ...
Source: Journal of Diagnostic Medical Sonography - March 13, 2013 Category: Radiology Authors: Sotoudehmanesh, R., Mirzaagha, F., Kolahdoozan, S. Tags: Original Articles Source Type: research

Successful Atrioesophageal Fistula Repair After Atrial Fibrillation Ablation
A 50-year-old woman with chronic kidney disease and rheumatoid arthritis underwent radiofrequency catheter ablation for symptomatic persistent atrial fibrillation. The patient sought treatment at the emergency room after 4 weeks with minor hematemesis. Esophagogastroduodenoscopy revealed a thrombus along the esophageal wall (A). Computed tomography scans of the chest demonstrated abnormal contouring of the left atrial wall, concerning for atrioesophageal fistula and pleural effusions (B and C, red arrow). Emergency cardiac and esophageal surgery was performed, during which the left atrium was repaired via a pericardial pat...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - March 11, 2013 Category: Cardiology Source Type: research

Transnasal Esophagogastroduodenoscopy for Evaluation of Upper Gastrointestinal Non‐Neoplastic Disorders in Patients With Fresh Hypopharyngeal Cancer
Conclusions:Transnasal esophagogastroduodenoscopy can be a single procedure to diagnose hypopharyngeal cancer and UGI disorders at one session. Approximately ⅔ of the patients with fresh hypopharyngeal cancer had either erosive esophagitis, active H. pylori infection, or gastric/duodenal ulcers. (Source: The Laryngoscope)
Source: The Laryngoscope - March 11, 2013 Category: ENT & OMF Authors: Cheng‐Ping Wang, Ping‐Huei Tseng, Tseng‐Cheng Chen, Pei‐Jen Lou, Tsung‐Lin Yang, Ya‐Ling Hu, Jenq‐Yuh Ko, Tzu‐Yu Hsiao, Yi‐Chia Lee Tags: Laryngology Source Type: research

Electrical tissue impedance spectroscopy: a novel device to measure esophageal mucosal integrity changes during endoscopy
Conclusions & InferencesElectrical tissue impedance spectroscopy is a new tool that can be used to evaluate esophageal mucosal integrity changes during endoscopy. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - March 11, 2013 Category: Gastroenterology Authors: P. W. Weijenborg, W. O. A. Rohof, L. M. A. Akkermans, J. Verheij, A. J. P. M. Smout, A. J. Bredenoord Tags: Original Article Source Type: research

Characteristics of Belching, Swallowing and Gastroesophageal Reflux in Belching Patients Based on Rome III Criteria
ConclusionsSB patients presented with more belching events, compared with GB patients. However, air swallowing and reflux profile were similar among the SB, GB patients and normal controls. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - March 11, 2013 Category: Gastroenterology Authors: Jianbo Li, Yinglian Xiao, Sui Peng, Jinkun Lin, Minhu Chen Tags: Clinical Gastroenterology Source Type: research

Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a chronic immune-mediated condition whereby infiltration of eosinophils into the esophageal mucosa leads to symptoms of esophageal dysfunction. EoE is encountered in a substantial proportion of patients undergoing diagnostic upper endoscopy. This review discusses the clinical, endoscopic, and histologic features of EoE and presents the most recent guidelines for its diagnosis. Selected diagnostic dilemmas are described, including distinguishing EoE from gastroesophageal reflux disease and addressing the newly recognized clinical entity of proton-pump inhibitor–responsive esophageal eosin...
Source: Gastroenterology Clinics of North America - March 1, 2013 Category: Gastroenterology Authors: Evan S. Dellon Source Type: research

Characteristics of esophageal proper muscle in patients with non‐cardiac chest pain using high‐frequency intraluminal ultrasound
ConclusionsUsing HFIUS, patients with GERD‐negative NCCP had increased muscle thickness and CSA. Some GERD‐negative NCCP had the incomplete peristaltic type. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - February 26, 2013 Category: Gastroenterology Authors: Jeong Hwan Kim, Yong Sung Choi, Jae J Kim, Jong Chul Rhee, Poong‐Lyul Rhee Tags: Gastroenterology Source Type: research

An Unusual Case of Chronic Diarrhea
Question: An 80-year-old man with a history of Henoch–Schonlein purpura at the age of 59 requiring partial jejunal resection, coronary artery disease, chronic kidney disease, gout, gastroesophageal reflux disease, and prior cholecystectomy was admitted for 2 weeks of guaiac-positive watery brown diarrhea and dehydration. Medications included aspirin 81 mg/d, clopidogrel, aldactazide, furosemide, hydralazine, isosorbide mononitrate, metoprolol, simvastatin, lansoprazole, allopurinol, trazodone, and tamsulosin. He had switched from citalopram to bupropion 2 weeks prior. He was afebrile and hemodynamically stable. His abdom...
Source: Gastroenterology - February 26, 2013 Category: Gastroenterology Authors: Gauree Gupta Konijeti, Vikram Deshpande, Cheryl J. Bunker Tags: Clinical Challenges and Images in GI Source Type: research

A Common Finding in an Uncommon Location
Question: A 52-year-old man with a history of end-stage renal disease secondary to focal segmental glomerulosclerosis status post renal transplant presented to the hospital with acute onset nausea, vomiting, and epigastric pain. The gastroenterology consult team was asked to evaluate him for these symptoms. Home medication list was notable for ferrous sulfide, hydralazine, clonidine, amlodipine, and as needed lactulose for opiate-induced constipation. Previous esophagogastroduodenoscopy from 6 years prior was normal. Physical examination was notable for only mild abdominal distention and tenderness. Abdominal x-ray on admi...
Source: Gastroenterology - February 26, 2013 Category: Gastroenterology Authors: Jonathan Congeni, Edward J. Levine Tags: Electronic Clinical Challenges and Images in GI Source Type: research

A Rare but Unique Tumor in the Esophagus
Question: A 72-year-old woman presented with progressive dysphagia and loss of 2 kg of body weight in 6 months. She denied heartburn or habitual consumption of cigarettes, alcohol, or betel quid. Physical examination and laboratory studies were normal. Esophagogastroduodenoscopy revealed several discrete, salmon-colored polypoid lesions (0.7–2.0 cm) in mid third of the esophagus (25–28 cm from the incisors; ). Endoscopic ultrasonography showed that the smaller tumors only involved mucosa, but the larger ones invaded through muscular propria, (, arrow). (Source: Gastroenterology)
Source: Gastroenterology - February 25, 2013 Category: Gastroenterology Authors: I-Chen Wu, Jui-Ying Lee, Chun-Chieh Wu Tags: Clinical Challenges and Images in GI Source Type: research

Meperidine as the single sedative agent during esophagogastroduodenoscopy, a double‐blind, randomized controlled study
ConclusionsAfter receiving meperidine injection patients had better tolerance and less discomfort during diagnostic EGD. (NCT01547520) (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - February 22, 2013 Category: Gastroenterology Authors: Yu‐Hsi Hsieh, Hwai‐Jeng Lin, Jin‐Jian Hsieh, Kuo‐Chih Tseng, Chih‐Wei Tseng, Tsung‐Hsing Hung, Felix W. Leung Tags: Clinical Gastroenterology Source Type: research

Gastritis cystica profunda with a long stalk
A 48-year-old woman was referred to our hospital for evaluation of a long-stalked gastric polypoid lesion, which was found incidentally during upper endoscopy screening. Her medical history was unremarkable, and she did not describe having any GI symptoms. The results of physical examination were unremarkable. EGD showed a 1.5-cm polypoid lesion with an erythematous head () and a long pedicle (). EUS revealed an anechoic lesion with multiple septae, located superficially to the muscularis mucosa (). She underwent polypectomy by use of a detachable snare. Gross pathologic examination revealed multiple internal cystic portio...
Source: Gastrointestinal Endoscopy - February 22, 2013 Category: Gastroenterology Authors: Tae Hee Lee, Joon Seong Lee, So Young Jin Tags: At the Focal Point Source Type: research

Mucosal healing effect of mesalazine granules in naproxen-induced small bowel enteropathy.
CONCLUSION: According to the small bowel CE evaluation mesalazine granules significantly attenuated mucosal injuries in patients with moderate-to-severe enteropathies induced by naproxen. PMID: 23431027 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 14, 2013 Category: Gastroenterology Authors: Rácz I, Szalai M, Kovács V, Regőczi H, Kiss G, Horváth Z Tags: World J Gastroenterol Source Type: research

Effectiveness of gastric cancer screening programs in South Korea: Organized vs opportunistic models.
CONCLUSION: Compliance to the screening program is more important than the type of screening system used. PMID: 23430471 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 7, 2013 Category: Gastroenterology Authors: Kim BJ, Heo C, Kim BK, Kim JY, Kim JG Tags: World J Gastroenterol Source Type: research

Heyde's Syndrome Incidence and Outcome in Patients Undergoing Transcatheter Aortic Valve Implantation
Heyde's syndrome is the association between calcific aortic stenosis and gastrointestinal bleeding (GIB) due to angiodysplasia. This rare relationship is observed in approximately 3% of patients with aortic stenosis, and it was first suggested by Edward J. Heyde in 1958 (). The pathogenesis of Heyde's syndrome involves an acquired von Willebrand factor (vWF) deficiency secondary to aortic stenosis and other degenerative disease in elderly patients with concomitant GIB () (). Surgical aortic valve replacement (SAVR) is considered the “gold standard” therapy in patients with severe aortic stenosis (). Therefore, we hypot...
Source: Journal of the American College of Cardiology - February 6, 2013 Category: Cardiology Authors: Cosmo Godino, Ludovica Lauretta, Anna Giulia Pavon, Antonio Mangieri, Giacomo Viani, Alaide Chieffo, Stefano Galaverna, Azeem Latib, Matteo Montorfano, Alberto Cappelletti, Francesco Maisano, Ottavio Alfieri, Alberto Margonato, Antonio Colombo Tags: Research Correspondence Source Type: research

Patients' intuitive judgments about surveillance endoscopy in Barrett's esophagus: a review and application to models of decision‐making
Summary Adherence to practice guidelines for endoscopic surveillance of Barrett's esophagus is equivocal with evidence of underutilization and overutilization. While physicians report strong agreement with and adherence to recommended surveillance endoscopy (esophagogastroduodenoscopy [EGD]) guidelines, less is known about modifiable barriers and facilitators shaping patients' adherence behaviors. The aim of this study is to conduct a structured literature review of studies exploring patients' perspectives regarding surveillance EGD and to place these results within a conceptual framework. A structured literature review of...
Source: Diseases of the Esophagus - February 5, 2013 Category: Gastroenterology Authors: M. Hinojosa‐Lindsey, J. Arney, S. Heberlig, J. R. Kramer, R. L. Street, H. B. El‐Serag, A. D. Naik Tags: Original Article Source Type: research