ParvovirusThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you your search results in order of date.

Pages: 1 2 3 4 5 6 7 8 9

438 records returned

Pharmacological Activation of Guanine Nucleotide Exchange Factors for the Small GTPase Rap1 Recruits High-Affinity β1 Integrins as Coreceptors for Parvovirus B19: Improved Ex Vivo Gene Transfer to Human Erythroid Progenitor CellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)
Source: Human Gene Therapy - November 16, 2009 Category: Genetics & Stem Cells Tags: article Source Type: journals

Development and validation of reverse transcription loop-mediated isothermal amplification for detection of PRRSVEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To establish a reverse-transcription loop-mediated isothermal amplification (RT-LAMP) method for rapid detection of porcine reproductive and respiratory syndrome virus (PRRSV), four primers specific to six regions of the N gene were designed. After amplification in an isothermal water bath for 1 h, samples containing PRRSV generated the expected ladder-like products while porcine parvovirus, porcine circovirus, classic swine fever virus, pseudorabies virus, and swine testis cells generated no product. The sensitivity and specificity of the RT-LAMP assay were evaluated by comparison with reverse...
Source: Virus Genes - November 12, 2009 Category: Genetics & Stem Cells Tags: Virus Genes Source Type: journals

Development and evaluation of a VP3-ELISA for the detection of goose and Muscovy duck parvovirus antibodies.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, the VP3-ELISA is a sensitive and specific method for detecting antibodies against GPV or MDPV. PMID: 19913055 [PubMed - as supplied by publisher] (Source: Journal of Virological Methods)
Source: Journal of Virological Methods - November 10, 2009 Category: Virology Authors: Zhang Y, Li Y, Liu M, Zhang D, Guo D, Liu C, Zhi H, Wang X, Li G, Tong G Tags: J Virol Methods Source Type: journals

The Human Bocaviruses: A Review and Discussion of Their Role in InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article is a comprehensive review of what is known about HBoV. It includes an evaluation of diagnostic modalities, symptoms occurring in affected patients, and a discussion as to whether HBoV is responsible for identified clinical manifestations. The article reviews the incidence and effect of coinfection and updates on related members (HBoV-2 and HBoV-3) recently reported. Understanding of respiratory viruses such as HBoV remains vitally important to the health of adult and pediatric patients. (Source: Clinics in Laboratory Medicine)
Source: Clinics in Laboratory Medicine - November 4, 2009 Category: Laboratory Medicine Authors: Brian D.W. Chow, Frank P. Esper Source Type: journals

What Is Erythema Infectiosum? What Is Slapped Cheek Syndrome?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Eythema infectiosum is also known as parvovirus infection, slapped cheek disease, or fifth disease. It is a disease caused by the parvovirus B19 and includes such symptoms as low-grade fever, tiredness, rash on the cheeks (hence "slapped cheek"), and also a rash all over the person's body. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 4, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Diarrhea in collective kennelsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Diarrhea is one of the most frequently reported concerns in kennels. Diarrhea is not a disease; it is only a sign that can have several infectious and non-infectious etiologies. When diarrhea occurs chronically it is very important to identify those causes, especially in the case of kennel medicine. The pathophysiology of diarrhea is complex and can include changes in peristalsis, increased digestive gland secretions, or decreased absorption. The clinical form of diarrhea depends on the localization of the pathology. Small bowel diarrhea induces watery stools with an increase in volume, sometimes with melena, and can be a...
Source: Journal of Veterinary Behavior: Clinical Applications and Research - November 1, 2009 Category: Veterinary Research Authors: Grégory Casseleux Tags: Abstracts Source Type: journals

[Genetic diversity of human erythroviruses. Consequences on infectious safety of plasma derivatives.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The B19 Parvovirus (B19V) has for a long time been considered as the unique human virus belonging to the genus Erythrovirus. The genetic diversity of B19V isolates has been shown to be very low. The isolation of a variant (V9 strain), with a sequence markedly distinct from that of B19V which led to attributing this classification to this family of viruses. Phylogenetic analysis of sequences of V9-related isolates indicates an organization into three well-individualized genotypes. The B19V infection can be transmitted by transfusion. In immunocompetent recipients, B19V exposure by transfusion is most often inconsequenti...
Source: Transfusion Clinique et Biologique - October 30, 2009 Category: Hematology Authors: Servant-Delmas A, Mercier M, Laperche S, Lefrère JJ Tags: Transfus Clin Biol Source Type: journals

Epithelial raft cultures for investigations of virus growth, pathogenesis and efficacy of antiviral agents.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The organotypic epithelial raft cultures, originally developed to study keratinocytes differentiation, represent a novel approach to the study of viruses able to infect epithelial cells. Organotypic epithelial raft cultures accurately reproduce the process of epithelial differentiation in vitro and can be prepared from normal keratinocytes, explanted epithelial tissue, or established cell lines. This culture system permits cells to proliferate and fully differentiate at the air-liquid interface on a dermal-equivalent support. Normal primary human keratinocytes (PHKs) stratify and fully differentiate in a manner similar...
Source: Antiviral Research - October 30, 2009 Category: Virology Authors: Andrei G, Duraffour S, Van den Oord J, Snoeck R Tags: Antiviral Res Source Type: journals

Prevalence of Parvovirus B19 and Human Bocavirus DNA in the Heart of Patients with no Evidence of Dilated Cardiomyopathy or MyocarditisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Our data suggest that B19V but not HBoV demonstrates a lifelong persistence in the heart. The detection of B19V DNA in heart tissue showed no correlation with clinical symptoms. We strongly recommend that serological testing become a standardized procedure for future studies, to obtain representative data concerning the prevalence of B19V in the heart. (Source: Clinical Infectious Diseases Latest Issue)
Source: Clinical Infectious Diseases Latest Issue - October 28, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

Detection of Human Bocavirus-2 in children with acute Gastroenteritis in South KoreaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Human bocavirus (HBoV)-2, a new parvovirus, has been identified in stool samples and is suggested to be one of the etiologic agents of acute gastroenteritis (GE). The purpose of this study was to investigate the prevalence of HBoV-2 in children with GE. Stool samples were collected from 358 children hospitalized with GE. HBoV-2 was detected in 3.6% of the patients. HBoV-2 was co-detected with other viral agents in 53.8% of the patients. These findings suggest that HBoV-2 may be an etiologic agent in GE, but further studies are needed due to frequent co-detection with other enteric viruses. Conten...
Source: Archives of Virology - October 28, 2009 Category: Virology Tags: Archives of Virology Source Type: journals

Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study aimed to investigate the impact of B19V infection in European patients with viral hepatitis. B19V DNA was detected in 1/91 and 0/50 serum samples from patients with chronic hepatitis C and B, respectively. In contrast, B19V DNA was amplified frequently from explanted end-stage liver tissues (37/50, 74%) and from routine biopsy samples (14/32, 44%) (P < 0.05). However, there was no significant difference in B19V copy number per cell between these two groups. B19V-specific CD4+ T-cell responses to two dominant MHC-class-restricted epitopes were detected in a similar frequency in healthy anti-B19V-positive individu...
Source: Journal of Medical Virology - October 25, 2009 Category: Virology Authors: Chun Wang, Albert Heim, Verena Schlaphoff, P.V. Suneetha, Kerstin A. Stegmann, Hong Jiang, Martin Krueger, Paraskevi Fytili, Thomas Schulz, Markus Cornberg, Reinhard Kandolf, Michael P. Manns, C. Thomas Bock, Heiner Wedemeyer Tags: Research Article Source Type: journals

A linked donor-recipient study to evaluate parvovirus B19 transmission by blood component transfusionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parvovirus B19V infection can be a serious infection for hematology patients with underlying hemolysis or compromised erythropoiesis syndromes. Although case reports of B19V transmission by blood component transfusion (as contrasted to manufactured plasma derivatives) are rare, no studies have systematically determined a rate of transmission to recipients transfused with B19V DNA–positive components. We used a linked donor and recipient repository and a sensitive, quantitative B19V DNA polymerase chain reaction (PCR) assay to assess such transmission in B19V-susceptible (ie, anti-B19V immunoglobulin G [IgG] negative)...
Source: Blood - October 22, 2009 Category: Hematology Authors: Kleinman, S. H., Glynn, S. A., Lee, T.-H., Tobler, L. H., Schlumpf, K. S., Todd, D. S., Qiao, H., Yu, M.-y. W., Busch, M. P., for the National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Study-II (NHLBI REDS-II) Tags: Transfusion Medicine, Free Research Articles, Red Cells, Iron, and Erythropoiesis Source Type: journals

Proteins selectively killing tumor cells.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
All human cells have a genetic program that upon activation will cause cell death, named apoptosis. Cancer cells can grow due to unbalances in proliferation, cell-cycle regulation and their apoptosis machinery: genomic mutations resulting in non-functional pro-apoptosis proteins or over-expression of anti-apoptosis proteins form the basis of tumor formation. Surprisingly, lessons learned from viruses show that cancer cannot be regarded simply as the opposite of apoptosis. For instance, adenovirus can only transform cells when both its anti- and pro-apoptotic proteins are produced. Oncolytic viruses are known to replica...
Source: European Journal of Pharmacology - October 13, 2009 Category: Drugs & Pharmacology Authors: Noteborn MH Tags: Eur J Pharmacol Source Type: journals

Parvovirus B19-induced Thrombocytopenia and Anemia in a Child with Fatal Fulminant Hepatic Failure Coinfected with Hepatitis A and E VirusesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 5-year-old male, drowsy, jaundiced child presented with fulminant hepatitis and had HAV and HEV infection. He had hepatic encephalopathy grade 1, fever, pallor, hypotension, crepitations in his right lung base and hepatosplenomegaly with dyspnoea. He had highly raised liver enzymes and hypoalbuminemia (2.8 g/dl) but anemia (hemoglobin of 7.7 g/dl and 5.7 g/dl 2 days later), reticulocytopenia and severe thrombocytopenia (44 x 109/l) were unexplained. Parvovirus B19-specific IgM antibodies and B19 DNA were found in the serum of the child. Chest X-ray showed pleural effusion and bronchopneumonia, while blood culture isolate...
Source: Journal of Tropical Pediatrics - October 12, 2009 Category: Tropical Medicine Authors: Kishore, J., Sen, M. Tags: Case Reports Source Type: journals

Information on 5th disease (slapped cheek disease) for parentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Information and photos of 5th disease, also known as slapped cheek disease, erythema infectiosum and parvovirus infection. (Source: Blog from a Pediatrician)
Source: Blog from a Pediatrician - October 6, 2009 Category: Pediatrics Source Type: consumer

Detection of Viral DNA in Kidney Graft Preservation and Washing Solutions Is Predictive of Posttransplant Infections in Pediatric RecipientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Molecular testing of donor grafts for viruses that infect circulating and resident cells in the graft—such as B19 in the kidney—could be useful (in association with donor/recipient serostatus) for identifying recipients at high risk for posttransplant infections. (Source: The Journal of Infectious Diseases Latest Issue)
Source: The Journal of Infectious Diseases Latest Issue - October 5, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

Human bocavirus 2 in children, South Korea.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: In 2009, Kapoor et al. and Arthur et al. published reports on the prevalence of the newly identified parvovirus, human bocavirus 2 (HBoV-2), in fecal samples (1,2). HBoV-1 had been discovered in 2005 (3), and reports indicate its possible role in respiratory diseases such as upper respiratory tract infections, lower respiratory tract infections (LRTIs), and in exacerbation of asthma (4); in these diseases, the virus co-infects with other respiratory viruses (5). Systemic infection with HBoV-1 and possible association of this virus with other diseases such as gastroenteritis, Kawasaki disease, and hepatit...
Source: Emerging Infectious Diseases - October 1, 2009 Category: Infectious Diseases Authors: Han TH, Chung JY, Hwang ES Tags: Emerg Infect Dis Source Type: journals

Multi-Immunogenic Outer Membrane Vesicles Derived from an MsbBDeficient Salmonella enterica Serovar Typhimurium Mutant.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To develop low endotoxic and multi-immunogenic outer membrane vesicles (OMVs), a deletion mutant of the msbB gene in Salmonella enterica serovar Typhimurium (S. Typhimurium) was used as a source of low endotoxic OMV, and an expression vector of the canine parvovirus (CPV) VP2 epitope fused to the bacterial OmpA protein was constructed and transformed into the Salmonella yenAmsbB mutant. In a lethality test, BALB/c mice injected intraperitoneally with the Salmonella yenAmsbB mutant survived for 7 days, whereas mice injected intraperitoneally with the wild type survived for 3 days. Moreover, all mice inoculated orally wi...
Source: Journal of Microbiology and Biotechnology - October 1, 2009 Category: Biotechnology Authors: Lee SR, Kim SH, Jeong KJ, Kim KS, Kim YH, Kim SJ, Kim E, Kim JW, Chang KT Tags: J Microbiol Biotechnol Source Type: journals

Management and Outcome of Pregnancies with Parvovirus B19 Infection over Seven Years in a Tertiary Fetal Medicine UnitEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fetal Diagn Ther 2009;25:373-378 (DOI:10.1159/000236149) (Source: Karger Publishers)
Source: Karger Publishers - September 29, 2009 Category: Cancer & Oncology Source Type: journals

When Does the Rash of Roseola Occur?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion Rashes, particularly ones caused by viruses, are common presenting problems. In his first edition of Pediatrics, Dr. Rotch spent 72 pages describing infectious exanthemata. The cause of the exanthemata was unknown at the time, and thankfully many of those that he wrote of have been eradicated (smallpox), have effective vaccines to prevent (measles, rubella, varicella) or effective antibiotics for treatment (streptococcus). Dr. Rotch ends his extensive treatise with a table describing “the chief points of differential diagnosis in the exanthemata.” This is what was state-of-the-art in 1896 with his s...
Source: PediatricEducation.org - September 28, 2009 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: info

Maternal human parvovirus B19 infection and the risk of fetal death and low birthweight: a case-control study within 35 940 pregnant women.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Maternal parvovirus B19 infection was not associated with fetal death in our study. Very few cases of fetal death may be attributed to maternal parvovirus B19 infection. PMID: 19769750 [PubMed - in process] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 24, 2009 Category: OBGYN Authors: Sarfraz AA, Samuelsen SO, Bruu AL, Jenum PA, Eskild A Tags: BJOG Source Type: journals

Prevalence of persistent and latent viruses in untreated patients infected with HIV-1 from Ghana, West AfricaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was conducted to determine the prevalence of persistent viruses in individuals with untreated HIV-1 infection and uninfected blood donors. Paired plasma and cellular samples from HIV-negative blood donors, asymptomatic HIV and symptomatic/AIDS cohorts were screened by multiplex PCR then qPCR for parvovirus B19 (B19V), hepatitis B virus (HBV), GB virus-C (GBV-C), cytomegalovirus (CMV), Epstein-Barr virus (EBV), human herpesvirus-8 (HHV-8) and varicella-zoster virus (VZV). IgG antibodies specific to each target virus were tested to determine exposure rates. No evidence of viraemia was found for B19V and VZV in any...
Source: Journal of Medical Virology - September 21, 2009 Category: Virology Authors: Lara Isobel Compston, Chengyao Li, Francis Sarkodie, Shirley Owusu-Ofori, Ohene Opare-Sem, Jean-Pierre Allain Tags: Research Article Source Type: journals

A prospective study of multiple donor exposure blood recipients: surveillance value and limitations for hemovigilance.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The risk of transfusion-associated B19 infection appears to be low but no conclusion of transfusion transmission can be made for Cp. The approach piloted through this study offers added value beyond the current hemovigilance strategy in the United States. PMID: 19778336 [PubMed - as supplied by publisher] (Source: Transfusion)
Source: Transfusion - September 21, 2009 Category: Hematology Authors: Zou S, Wu Y, Cable R, Dorsey K, Tang Y, Hapip CA, Melmed R, Trouern-Trend J, Carrano D, Champion M, Fujii K, Fang C, Dodd R Tags: Transfusion Source Type: journals

[Seroprevalence of human parvovirus B19 in ambulatory population of Cantabria, northern Spain.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19783492 [PubMed - as supplied by publisher] (Source: Anales de Pediatria)
Source: Anales de Pediatria - September 21, 2009 Category: Pediatrics Authors: Ruiz de Alegría Puig C, Balbás García de Bustos R, Herrera González MC, Martínez-Bernal MA Tags: An Pediatr (Barc) Source Type: journals

Porcine parvovirus- and porcine circovirus 2-associated reproductive failure and neonatal mortality in crossbred Indian pigsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to detect the presence of porcine parvovirus (PPV) and porcine circovirus 2 (PCV2) in a farm showing reproductive failure and increased mortality in neonatal piglets by histopathological examination, polymerase chain reaction, and demonstration of viral antigen and nucleic acid. Out of 594 piglets farrowed by 70 first-parity gilts, nine (1.51%) mummified fetuses, 13 (2.19%) stillborn, and 572 (96.3%) live-born piglets were recorded. The average litter size at birth was 8.48 piglets per litter. One hundred ninety-four (33.91%) piglets died within 7 days of age. PPV was detected in f...
Source: Tropical Animal Health and Production - September 17, 2009 Category: Veterinary Research Tags: Tropical Animal Health and Production Source Type: journals

Sequence analysis of an isolate of minute virus of canines in China reveals the closed association with bocavirus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the present study, we have cloned and sequenced the nearly-full-length genome of minute virus of canines (MVC), SH26, in China. The genome of MVC, 5,132 nucleotides (nts) in length, contains three open reading frames (ORFs), which are 2,325-bp of NS1, 561-bp of NP1 and 2,112-bp of VP1/VP2 encoding three proteins of 774, 186 and 703 residues, respectively. Predicted amino acids sequence of NS1 of MVC has 44% identity with human bocavirus (HBoV) and human boacvirus 2 (HBoV2), NP1 has 48 and 45% identity with HBoV and HBoV2, VP1/VP2 has 45 and 46% identity with HBoV and HBoV2, respectively. Phylogenetic analysis showed...
Source: Molecular Biology Reports - September 16, 2009 Category: Molecular Biology Authors: Shan TL, Cui L, Dai XQ, Guo W, Shang XG, Yu Y, Zhang W, Kang YJ, Shen Q, Yang ZB, Zhu JG, Hua XG Tags: Mol Biol Rep Source Type: journals

Epstein-Barr virus and parvovirus B19 coinfection in a Crohn's disease patient under azathioprineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
No abstract. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - September 15, 2009 Category: Gastroenterology Authors: Teresa Moreira, Paula Lago, Marta Salgado, Rita Pimentel Source Type: journals

Development of a fluorescent quantitative real-time polymerase chain reaction assay for the detection of Goose parvovirus in vivoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The high sensitivity, specificity, simplicity, and reproducibility of the GPV fluorogenic PCR assay, combined with a high throughput, make this method suitable for a broad spectrum of GPV etiology-related applications. (Source: Virology Journal)
Source: Virology Journal - September 14, 2009 Category: Virology Authors: Jin-Long YangAn-Chun ChengMing-Shu WangKang-Cheng PanMin LiYu-Fei GuoChuan-Feng LiDe-Kang ZhuXiao-Yue Chen Source Type: journals

Serum α-1-acid glycoprotein concentration in clinically healthy puppies and adult dogs and in dogs with various diseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
[alpha]-1-acid glycoprotein (AGP) is an acute-phase protein and a serum marker of inflammation and neoplasia in humans. AGP concentrations in diseased dogs and the potential effects of age, breed, and sex have not been elucidated. The purpose of this study was to examine differences in AGP concentration based on age, sex, and breed in a large population of clinically healthy dogs and to compare AGP concentrations in dogs with various diseases. Serum was obtained from clinically healthy puppies (n=74) and adults (n=172) of both sexes, and included mongrels (n=205) and Beagles (n=41). Serum also was obtained from 192 dogs wi...
Source: Veterinary Clinical Pathology - September 14, 2009 Category: Veterinary Research Authors: Masashi Yuki, Hiroshi Itoh, Katsuaki Takase Source Type: journals

Clinical and epidemiological aspects of parvovirus B19 infections in Ireland, January 1996-June 2008.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parvovirus B19 infection may be mistakenly reported as measles or rubella if laboratory testing is not performed. As Europe is seeking to eliminate measles, an accurate diagnosis of fever/rash illnesses is needed. The main purpose of this study was to describe the epidemiological pattern of parvovirus B19, a common cause of rash, in Ireland between January 1996 and June 2008, using times series analysis of laboratory diagnostic data from the National Virus Reference Laboratory. Most diagnostic tests for presumptive parvovirus B19 infection were done in children under the age of five years and in women of child-bearing ...
Source: Euro Surveill - September 11, 2009 Category: Infectious Diseases Authors: Nicolay N, Cotter S Tags: Euro Surveill Source Type: journals

Detection of a novel porcine boca-like virus in the background of porcine circovirus type 2 induced postweaning multisystemic wasting syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study we explored the possible presence of other so-far unknown DNA containing infectious agents in lymph nodes collected from Swedish pigs with confirmed PMWS through random amplification and high-throughput sequencing. Although the vast majority of the amplified genetic sequences belonged to PCV-2, we also found genome sequences of Torque Teno virus (TTV) and of a novel parvovirus. The detection of TTV was expected since like PCV-2, TTV has been found to have high prevalence in pigs around the world. We were able to amplify a longer region of the parvovirus genome, consisting of the entire NP1 and partial VP1/2. ...
Source: Virus Research - September 9, 2009 Category: Virology Authors: Blomström AL, Belák S, Fossum C, McKillen J, Allan G, Wallgren P, Berg M Tags: Virus Res Source Type: journals

Azathioprine: Parvovirus B19 infection leading to leucopenia: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - September 7, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

[Risks and side effects of blood transfusion.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article addresses the incidence, clinical picture, and etiology of adverse effects of transfusion. It also reports on current knowledge concerning transfusion-associated acute lung injury, which has gained much attention in the last few years. Besides hepatitis and human immunodeficiency viruses, cytomegalovirus, parvovirus B19, prion transmission, and the risk of variant Creutzfeld-Jakob disease are also discussed. PMID: 19756492 [PubMed - as supplied by publisher] (Source: Der Orthopade)
Source: Der Orthopade - September 5, 2009 Category: Orthopaedics Authors: Fölsch B, Cassens U Tags: Orthopade Source Type: journals

Seroepidemiological study of human parvovirus B19 among human immunodeficiency virus-infected patients in a medium-sized city in Rio de Janeiro, Brazil.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Parvovirus B19 (B-19) may cause chronic anaemia in immunosuppressed patients, including those infected with human immunodeficiency virus (HIV). We studied single serum samples from 261 consecutive HIV-infected patients using an enzyme immunoassay to detect IgG antibodies to B-19. The seroprevalence of B-19-IgG was 62.8%. The differences in seroprevalence across gender, age, educational categories, year of collection of the serum samples, clinical and antiretroviral therapy characteristics, CD4+ count, CD4+ and CD8+ percentage and CD4+/CD8+ ratios were neither substantial nor statistically significant. There was a non-s...
Source: Memorias do Instituto Oswaldo Cruz - September 1, 2009 Category: Infectious Diseases Authors: Azevedo KM, Setúbal S, Camacho LA, Velarde LG, Oliveira SA Tags: Mem Inst Oswaldo Cruz Source Type: journals

Relationship among epidemiological parameters of six childhood infections in a non-immunized Brazilian community.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Epidemiological parameters, such as age-dependent force of infection and average age at infection (<IMG SRC='../img/13s1.gif' WIDTH=9 HEIGHT=12>) were estimated for rubella, varicella, rotavirus A, respiratory syncytial virus, hepatitis A and parvovirus B19 infections for a non-immunized Brazilian community, using the same sera samples. The for the aforementioned diseases were 8.45 years (yr) [95% CI: (7.23, 9.48) yr], 3.90 yr [95% CI: (3.51, 4.28) yr], 1.03 yr [95% CI: (0.96, 1.09) yr], 1.58 yr [95% CI: (1.39, 1.79) yr], 7.17 yr [95% CI: (6.48, 7.80) yr] and 7.43 yr [95% CI: (5.68, 9.59) yr], respectively. The d...
Source: Memorias do Instituto Oswaldo Cruz - September 1, 2009 Category: Infectious Diseases Authors: Amaku M, Azevedo RS, Castro RM, Massad E, Coutinho FA Tags: Mem Inst Oswaldo Cruz Source Type: journals

Facial rash in a pregnant womanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Case presentation A 24-year-old pregnant woman presented to her General Practitioner at 20 weeks gestation. She gave a 5-day history of vague symptoms, consisting principally of epigastric pain and a mild cough. A community pharmacist had noted a facial rash, raised the concern of ‘slapped cheek syndrome’ and advised her to seek medical attention. She was otherwise well and the pregnancy had been uneventful. Rubella IgG had been detected on routine antenatal screening at 12 weeks gestation, and an ultrasound scan at that point had been unremarkable. A current serum sample and the booking serum sample were submitted fo...
Source: Journal of Clinical Virology - August 31, 2009 Category: Virology Authors: Sheila Waugh, Kevin E. Brown Tags: Virology Question and Answer Scheme Source Type: journals

Parvovirus B19 induced hepatic failure in an adult requiring liver transplantation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a 55-year-old immunocompetent woman who developed fulminant hepatic failure after acute infection with Parvovirus B19 who subsequently underwent orthotopic liver transplantation. This is believed to be the first reported case in the literature in which an adult patient with fulminant hepatic failure associated with acute parvovirus B19 infection and without hematologic abnormalities has been identified prior to undergoing liver transplantation. This case suggests that Parvovirus B19 induced liver disease can affect adults, can occur in the absence of hematologic abnormalities and can be severe enough ...
Source: World Journal of Gastroenterology : WJG - August 27, 2009 Category: Gastroenterology Authors: Krygier DS, Steinbrecher UP, Petric M, Erb SR, Chung SW, Scudamore CH, Buczkowski AK, Yoshida EM Tags: World J Gastroenterol Source Type: journals

Phylogenetic analysis of a near-full-length sequence of an erythrovirus genotype 3 strain isolated in BrazilEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Human parvovirus B19 is the only member of the genus Erythrovirus that causes human disease. Recent findings of several strains with considerable sequence divergence from B19 have suggested a new classification for parvovirus genotypes as 1 (B19), 2 (A-6 and LaLi) and 3 (V9). In their overall DNA sequence, the three genotypes differ by ~10%. Here, we report the isolation of a genotype-3-related strain named BR543 during a prospective study conducted in Sao Paulo, Brazil. Analysis of the nearly full-length genome sequence of BR543 indicates that this B19 variant sequence clusters with Gh2768, a strai...
Source: Archives of Virology - August 22, 2009 Category: Virology Tags: Archives of Virology Source Type: journals

High Frequencies of Exposure to the Novel Human Parvovirus PARV4 in Hemophiliacs and Injection Drug Users, as Detected by a Serological Assay for PARV4 AntibodiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. The present study provides convincing evidence that PARV4 is primarily transmitted parenterally. Evidence for widespread infection of hemophiliacs treated with nonvirally inactivated clotting factor creates fresh safety concerns for plasma‐derived blood products, particularly because parvoviruses are relatively resistant to virus inactivation. (Source: The Journal of Infectious Diseases Latest Issue)
Source: The Journal of Infectious Diseases Latest Issue - August 19, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

Influence of amplicon size on the polymerase chain reaction of Parvovirus B19 genome in formalin-fixed specimensEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, although PCR is highly specific and sensitive in fresh or ideally fixed material, a careful standardization of PCR assays is necessary when using formalin fixed paraffin-embedded tissues by applying primers that require smaller DNA fragments for amplification.A reação em cadeia da polimerase (PCR) tem fornecido diagnóstico de material de arquivo, mas alguns métodos de fixação, tais como formalina, provocam danos ao DNA e subsequentemente afetam sua análise, particularmente tecidos embebidos em parafina. A PCR é conhecida pela sua alta especificidade e sensibilidade, embora algumas dificuldades ocorra...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - August 14, 2009 Category: Pathology Source Type: journals

Chronic parvovirus B19 infection leading to red cell aplasia following treatment of Hodgkin lymphomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: British Journal of Haematology)
Source: British Journal of Haematology - August 12, 2009 Category: Hematology Authors: Sarah Poplar, Sarah Allford, Nicholas Rooney Source Type: journals

Fulminant parvovirus B19-associated pancarditis with haemophagocytic lympho-histiocytosis in an immunocompetent adultEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe autopsy findings of a patient who had a lethal myocarditis with haemophagocytic lympho-histiocytosis in a course of systemic PVB19 infection. The present case illustrates the unusually severe and rapid course of PVB19 myocarditis with associated haemophagocytic lympho-histiocytosis leading to death. (Source: APMIS)
Source: APMIS - August 12, 2009 Category: Research Authors: AMANJIT BAL, BAIJAYANTIMALA MISHRA, NAVNEET SINGH, ASHIM DAS, SK JINDAL Source Type: journals

Acute infection with parvovirus B19 in early pregnancy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19644946 [PubMed - as supplied by publisher] (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - July 29, 2009 Category: Radiology Authors: Bizjak G, Blondin D, Hammer R, Kozlowski P, Siegmann HJ, Stressig R Tags: Ultrasound Obstet Gynecol Source Type: journals

Hyperthyroidism associated with human parvovirus B19 infectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - July 28, 2009 Category: Dermatology Authors: M. Seishima, Y. Shibuya, S. Suzuki Source Type: journals

Guidance for Industry: Nucleic Acid Testing (NAT) to Reduce the Possible Risk of Parvovirus B19 Transmission by Plasma-Derived ProductsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recommendations for performing nucleic acid testing (NAT) for human parvovirus B19 as an in-process test for Source Plasma and recovered plasma used in the further manufacturing of plasma-derived products. (Source: What's New at CBER)
Source: What's New at CBER - July 27, 2009 Category: Biomedical Science Source Type: organizations

Cloning, in vitro expression, and bioactivity of interleukin-18 isolated from a domestic porcine breed found in HenanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To evaluate the effects of recombinant porcine interleukin-18 (rpIL-18) on the replication of viruses in host cells and proliferation of lymphocytes, porcine IL-18 (pIL-18) isolated from a domestic big-white porcine breed found in the Henan province (HN) was cloned using a reverse transcriptase-PCR. The cloned HN pIL-18 contained an ORF of 579 base pairs encoding a 192-amino-acid precursor protein. The amino acid sequence of HN pIL-18 was compared with all the other pIL-18 amino acid sequences and varied by at least one amino acid to the consensus of all the others available. HN pIL-18 mature protein gene was inserted into...
Source: FEMS Immunology and Medical Microbiology - July 26, 2009 Category: Microbiology Authors: Hong-Ying Chen, Lan-Lan Zheng, Xin-Sheng Li, Zhan-Yong Wei, Bao-An Cui, Xiao-Kang Li, Jin-Peng Liu, Hong-Zheng Yin, Jiang-Tao Meng, Yan Zhang, Shi-Min Li Source Type: journals

Detection of parvovirus B19 in the lower respiratory tractEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Parvovirus B19 may be detected at low frequency in BAL specimens from patients with different pathological backgrounds. This finding could be due to chronic infection with virus persistence in the lower respiratory tract, also in the absence of symptoms unequivocally attributable to B19. The high rate of mortality warrants the need for further studies to evaluate the opportunity to consider parvovirus B19 in the diagnostic work-up of lower respiratory tract infections. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - July 26, 2009 Category: Virology Authors: Cristina Costa, Maria Elena Terlizzi, Paolo Solidoro, Daniela Libertucci, Massimiliano Bergallo, Rossana Cavallo Tags: Full length articles Source Type: journals

Molecular insights into the phylogeny of canine parvovirus 2 (CPV-2) with emphasis on Korean isolates: a Bayesian approachEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A Bayesian approach was utilized to further investigate the molecular phylogeny of canine parvovirus 2 (CPV-2) with emphasis on Korean isolates, and the complete VP2 gene sequences for 23 Korean isolates in 2007 and two vaccine strains were determined. Of the 44 Korean CPVs, 40 were identified as CPV-2a, three as CPV-2b, and the remaining one as a CPV-2a variant having a Gly300Asp mutation. Compared with CPV-2a, our findings also showed the presence of six additional amino acid substitutions (Thr440Ala, Ile418Thr, Pro435Ser, Asp413Asn, Thr322Ser, and Tyr324Ile) within the VP2 gene of the Korean isol...
Source: Archives of Virology - July 10, 2009 Category: Virology Tags: Archives of Virology Source Type: journals

Persistent Adeno-associated Virus 2 and Parvovirus B19 Sequences in Post-mortem Human Cerebellum.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We previously reported in a large cohort (N = 104) of post-mortem tissues the detection of both the non-pathogenic adeno-associated virus (AAV2) in approximately 13% and the pathogenic human parvovirus B19 (B19) in approximately 42% of human brains, particularly the dorsolateral prefrontal cortex. Multiple animal parvoviruses target the developing cerebellum (CBLM) resulting in hypoplasia and ataxia, but very little is known about the human parvoviruses and their ability to infect or cause disease in the CBLM. We have now confirmed in the above cohort the presence of AAV2 and B19 sequences in the CBLM. Our results show...
Source: Cerebellum - July 7, 2009 Category: Neuroscience Authors: Grant JK, Yin NC, Zaytoun AM, Waseem H, Hobbs JA Tags: Cerebellum Source Type: journals