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This page shows you the latest news and research items in this category.

Hospital mortality over time in patients with specific complications of liver cirrhosis
ConclusionsHospital mortality due to specific complications of liver cirrhosis is high, but has been declining in recent years.© 2013 John Wiley & Sons A/S (Source: Liver International)
Source: Liver International - February 24, 2013 Category: Gastroenterology Authors: Mercedes Vergara, Montse Clèries, Emili Vela, Montserrat Bustins, Mireia Miquel, Rafael Campo Tags: Original Article Source Type: research

Soluble urokinase plasminogen activator receptor (suPAR) is compartmentally regulated in decompensated cirrhosis and indicates immune activation and short‐term mortality
ConclusionBlood and ascitic suPAR levels provide distinct, but relevant prognostic information on the severity of complications in patients with end‐stage liver disease.© 2013 The Association for the Publication of the Journal of Internal Medicine (Source: Journal of Internal Medicine)
Source: Journal of Internal Medicine - February 21, 2013 Category: Internal Medicine Authors: Henning W Zimmermann, Philipp A Reuken, Alexander Koch, Matthias Bartneck, David H Adams, Christian Trautwein, Andreas Stallmach, Frank Tacke, Tony Bruns Tags: Original Source Type: research

Hepatorenal Syndrome in the Intensive Care Unit
Hepatorenal syndrome (HRS) is a functional form of acute kidney injury (AKI) associated with advanced liver cirrhosis or fulminant hepatic failure. Various new concepts have emerged since the initial diagnostic criteria and definition of HRS was initially published. These include better understanding of the pathophysiological mechanisms involved in HRS, identification of bacterial infection (especially spontaneous bacterial peritonitis) as the most important HRS-precipitating event, recognition that insufficient cardiac output plays a role in the occurrence of HRS, and evidence that renal failure reverses with pharmacother...
Source: Journal of Intensive Care Medicine - February 20, 2013 Category: Intensive Care Authors: Wadei, H. M., Gonwa, T. A. Tags: Analytic Reviews Source Type: research

Albumin: Pathophysiologic basis of its role in the treatment of cirrhosis and its complications
Abstract Since the introduction of human serum albumin as a plasma expander in the 1940s, considerable research has allowed a better understanding of its biochemical properties and potential clinical benefits. Albumin has a complex structure, which is responsible for a variety of biological functions. In disease, albumin molecule is susceptible to modifications that may alter its biological activity. During the last decades, different methods to measure albumin function have been developed. Recent studies have shown that not only albumin concentration but also albumin function is reduced in liver failure. This observation ...
Source: Hepatology - February 19, 2013 Category: Internal Medicine Authors: Rita Garcia‐Martinez, Paolo Caraceni, Mauro Bernardi, Pere Gines, Vicente Arroyo, Rajiv Jalan Tags: Liver Failure, Cirrhosis and Portal Hypertension Source Type: research

When illness strikes, living alone can be dangerous
She is a poster girl for singleton life. But a recent brush with death compelled Hannah Betts to consider the limitations of her unencumbered life. (Source: Telegraph Health)
Source: Telegraph Health - February 15, 2013 Category: Consumer Health News Tags: death singleton living alone appendictis peritonitis Source Type: news

Neutrophil Lyso-PS Regulates Tissue Neutrophilia [Lipids]
Resolution of neutrophilia characteristic of acute inflammation requires cessation of neutrophil recruitment and removal of tissue neutrophils. Based on in vitro studies, a role in these events was hypothesized for oxidant-generated lysophosphatidylserine (lyso-PS) on recruited neutrophils signaling via the G2A receptor on macrophages. Peritoneal exudate neutrophils harvested from wild type (WT) mice had 5-fold more lyso-PS (lyso-PShigh) than those of gp91phox−/− (lyso-PSlow) mice. Ex vivo engulfment of lyso-PShigh neutrophils (95% viable) by WT peritoneal macrophages was quantitatively similar to UV-irradiated apoptot...
Source: Journal of Biological Chemistry - February 15, 2013 Category: Chemistry Authors: Frasch, S. C., Fernandez-Boyanapalli, R. F., Berry, K. A. Z., Murphy, R. C., Leslie, C. C., Nick, J. A., Henson, P. M., Bratton, D. L. Tags: Cell Biology Source Type: research

Early experience with laparoscopic lavage for perforated diverticulitis
ConclusionLaparoscopic lavage for perforated diverticulitis was feasible in the majority of patients, but identification of an overt sigmoid perforation and patient selection are of critical importance. © 2013 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. (Source: British Journal of Surgery)
Source: British Journal of Surgery - February 13, 2013 Category: Surgery Authors: H. A. Swank, I. M. Mulder, A. G. M. Hoofwijk, S. W. Nienhuijs, J. F. Lange, W. A. Bemelman, Tags: Original Article Source Type: research

Mesothelial cell: A multifaceted model of aging.
Abstract Human peritoneal mesothelial cells (HPMCs) dominate within the peritoneal cavity and thus play a central role in a variety of intraperitoneal processes, including the transport of water and solutes, inflammation, host response, angiogenesis, and extracellular matrix remodeling. In addition, they contribute to the development of abdominal adhesions, peritonitis, endometriosis, cancer cell metastases, and peritoneal dialysis complications. For less than a decade the primary cultures of omental HPMCs have also been used as an experimental tool in studies on cellular aging. This paper provides the first compre...
Source: Ageing Research Reviews - February 13, 2013 Category: Genetics & Stem Cells Authors: Książek K Tags: Ageing Res Rev Source Type: research

[Management of penetrating abdominal trauma: What we need to know?]
Abstract Penetrating traumas are rare in France and mainly due to stabbing. Knives are less lethal than firearms. The initial clinical assessment is the cornerstone of hospital care. It remains a priority and can quickly lead to a surgical treatment first. Urgent surgical indications are hemorrhagic shock, evisceration and peritonitis. Dying patients should be immediately taken to the operating room for rescue laparotomy or thoracotomy. Ultrasonography and chest radiography are performed before damage control surgery for hemodynamic unstable critical patients. Stable patients are scanned by CT and in some cases may...
Source: Annales Francaises d'Anesthesie et de Reanimation - February 8, 2013 Category: Anesthesiology Authors: Hoffmann C, Goudard Y, Falzone E, Leclerc T, Planchet M, Cazes N, Pons F, Lenoir B, Debien B Tags: Ann Fr Anesth Reanim Source Type: research

High mortality of pneumonia in cirrhotic patients with ascites
Conclusion: Infectious diseases increased 30-day and 90-day mortality of cirrhotic patients with ascites. Among all infectious diseases identified, pneumonia carried the highest risk for mortality. (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - February 7, 2013 Category: Gastroenterology Authors: Tsung-Hsing HungChih-Wei TsengYu-Hsi HsiehKuo-Chih TsengChih-Chun TsaiChen-Chi Tsai Source Type: research

Extensive thrombosis in a patient with familial mediterranean Fever, despite hyperimmunoglobulin d state in serum - first adult case in Korea.
We report a 22-yr old boy who presented with fever, arthalgia and abdominal pain. He had a history of recurrent episodes of fever associated with arthalgia which would subside spontaneously or by antipyretics. Autosomal recessive periodic fever syndromes were suspected. Immunoglobulin D (IgD) level in the serum was elevated and DNA analysis showed complex mutations (p.Glu148Gln, p.Pro369Ser, p.Arg408Gln) in the MEFV gene. 3D angio computed tomography showed total thrombosis of splenic vein with partial thrombosis of proximal superior mesenteric vein, main portal vein and intrahepatic both portal vein. This is a case of FMF...
Source: J Korean Med Sci - February 1, 2013 Category: Journals (General) Authors: Joo K, Park W, Chung MH, Lim MJ, Jung KH, Heo Y, Kwon SR Tags: J Korean Med Sci Source Type: research

Genetic deletion of the HIF‐1α isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model
In this study, we investigated the role of isoform I.1, a quantitatively minor alternative isoform of HIF‐1α, in antibacterial immunity and sepsis survival. By using the cecal ligation and puncture model of bacterial peritonitis, we studied the function of I.1 isoform in T cells using mice with total I.1 isoform deficiency and mice with T‐cell‐targeted I.1 knockdown. We found that genetic deletion of the I.1 isoform resulted in enhanced resistance to septic lethality, significantly reduced bacterial load in peripheral blood, increased M1 macrophage polarization, augmented levels of proinflammatory cytokines in serum...
Source: European Journal of Immunology - January 31, 2013 Category: Allergy & Immunology Authors: Peter Georgiev, Bryan G. Belikoff, Stephen Hatfield, Akio Ohta, Michail V. Sitkovsky, Dmitriy Lukashev Tags: Regular Article Source Type: research

Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function
Conclusions: The MAP targets during resuscitation did not alter the inflammatory response, nor affected skeletal muscle ATP content and mitochondrial respiration. While targeting a lower MAP was associated with increased incidence of AKI, targeting a higher MAP resulted in increased net positive fluid balance and vasopressor load during resuscitation. The long-term effects of using lower MAP targets on kidney function and whether the resulting increased fluid balance and vasopressor load using higher MAP targets are of relevance for recovery after initial resuscitation needs to be evaluated in further long term studies. (S...
Source: Critical Care - January 30, 2013 Category: Intensive Care Authors: Thiago CorreaMadhusudanarao VudaJukka TakalaSiamak DjafarzadehEliezer SilvaStephan Jakob Source Type: research

An Unusual Cause of Recurrent Intestinal Obstruction
Question: A 56-year-old man with end-stage renal failure secondary to chronic glomerulonephritis presented with a 4-month history of symptoms suggestive of recurrent intermittent small bowel obstruction. He had previously undergone continuous ambulatory peritoneal dialysis (CAPD) between 2004 and 2011. However, this was complicated by CAPD peritonitis and the CAPD catheter was removed in September 2011. He has since been on hemodialysis via a left arm arteriovenous graft. For the past 4 months, he has experienced recurrent episodes of abdominal distension associated with bilious vomiting requiring multiple hospitalizations...
Source: Gastroenterology - January 28, 2013 Category: Gastroenterology Authors: Raj Vikesh Tiwari, Brian K.P. Goh, Terence Kee Tags: Electronic Clinical Challenges and Images in GI Source Type: research

Acid‐suppressive therapy is associated with spontaneous bacterial peritonitis in cirrhotic patients: A meta‐analysis
ConclusionsPharmacologic acid suppression was associated with a greater risk of SBP in hospitalized patients with cirrhosis. Cirrhotic patients receiving a PPI have approximately three times the risk of developing SBP compared with those not receiving this medication. Prospective studies may help clarify this relationship and shed light on the mechanism(s) by which acid‐suppressive therapy increases the risk of SBP in hospitalized patients with cirrhosis. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - January 22, 2013 Category: Gastroenterology Authors: Abhishek Deshpande, Vinay Pasupuleti, Priyaleela Thota, Chaitanya Pant, Sulaiman Mapara, Sohaib Hassan, David D K Rolston, Thomas J Sferra, Adrian V Hernandez Tags: Meta‐Analysys and Systematic Review Source Type: research

Aspergillus peritonitis in continuous ambulatory peritoneal dialysis patients
Basok A, Schneider E, Hausmann M, Rapoport J (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

The role of surgery and itraconazole in Aspergillus peritonitis in CAPD
Kitiyakara C, Sakulsaengprapha A, Domrongkitchaiporn S (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

Aspergillus peritonitis in peritoneal dialysis
Tanis BC, Verburgh CA, van der Pijl JW, van't Wout JW (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

Scanning electron microscopy studies of peritoneal catheter in CAPD peritonitis due to Aspergillus fumigatus
Park SB, Kim KH, Joo I, Kim HC (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

Aspergillus peritonitis in peritoneal dialysis: case report and a review of the literature
Tanis BC, Verburgh CA, van 't Wout JW, van der Pijl JW (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

Aspergillus peritonitis: therapy, survival, and return to peritoneal dialysis
Miles AM, Barth RH (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

Aspergillus peritonitis in a continuous ambulatory peritoneal dialysis patient. Case report and review of the literature
Nguyen MH, Muder RR (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

Peritonitis due to Aspergillus niger in a patient on continuous ambulatory peritoneal dialysis shortly after kidney graft rejection
Bibashi E, Papagianni A, Kelesidis A, Antoniadou R, Papadimitriou M (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

Successful treatment of Aspergillus peritonitis in an adult on continuous ambulatory peritoneal dialysis
Stein M, Levine JF, Black W (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

Successful treatment of Aspergillus peritonitis in a peritoneal dialysis patient
Matsumoto N, Shiraga H, Takahashi K, Kikuchi K, Ito K (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - January 21, 2013 Category: Respiratory Medicine Source Type: news

What can we learn from a patient on dialysis for 42 years?
Abstract We performed autopsy on a 60-year-old Japanese man who had received dialysis for 42 years. He started on intermittent peritoneal dialysis in 1968, which was combined with hemodialysis in 1969. His serum calcium-phosphate balance and his blood pressure had been controlled well. Carpal tunnel syndrome occurred in 1984. Then lumbar spinal canal stenosis (SCS) occurred in 1997, followed by cervical SCS in 2000, destructive lumbar spondyloarthropathy (DSA) in 2002, and pathological fracture of the right femoral neck due to an enlarging bone cyst in 2006. All of his surgical specimens showed dialysis-related dep...
Source: Clinical Nephrology - January 15, 2013 Category: Urology & Nephrology Authors: Suwabe T, Ubara Y, Inoue M, Kitajima I, Oohashi K, Nakano I, Takaichi K Tags: Clin Nephrol Source Type: research

Erysipelas-like erythema as a cutaneous sign of familial Mediterranean fever: A case report and review of the histopathologic findings
To the Editor: Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease affecting almost exclusively Eastern Mediterranean populations, in particular Jews, Armenians, Arabs, and Turks. Mutations in the marenostrin-encoding fever (MEFV) gene on chromosome 16p13.3 are responsible for the disease and 4 common mutations in exon 10 seem to account for 86% of DNA variations identified in patients with FMF. Marenostrin (also called pyrin) acts as an inhibitor of the nucleotide-binding domain leucine-rich repeat-containing receptors, pyrin domain containing 3 (NLRP3) inflammasome. Mutations in the MEFV...
Source: Journal of the American Academy of Dermatology - January 14, 2013 Category: Dermatology Authors: Sonja Radakovic, Gregor Holzer, Adrian Tanew Tags: JAAD Online Source Type: research

Malignant atrophic papulosis (Kohlmeier-Degos disease) - A review
Definition of the disease: Malignant atrophic papulosis (MAP), described independently by Kohlmeier and Degos et al., is a rare, chronic, thrombo-obliterative vasculopathy characterized by papular skin lesions with central porcelain-white atrophy and surrounding teleangiectatic rim.Epidemiology: Less than 200 cases have been described in the literature. The first manifestation of MAP usually occurs between the 20th and 50th year of life.Clinical description: The cutaneous clinical picture is almost pathognomonic. The histology is not consistent but in most cases it shows a wedge-shaped connective tissue necrosis in the dee...
Source: Orphanet Journal of Rare Diseases - January 14, 2013 Category: Internal Medicine Authors: Athanasios TheodoridisEvgenia MakrantonakiChristos Zouboulis Source Type: research

Alterations in the hemostatic profiles of dogs with naturally occurring septic peritonitis
ConclusionsDeficiencies of PC and AT and hypercoagulability appear to be consistent features of naturally occurring canine sepsis and may be useful prognostic indicators in canine septic peritonitis. (Source: Journal of Veterinary Emergency and Critical Care)
Source: Journal of Veterinary Emergency and Critical Care - January 14, 2013 Category: Veterinary Research Authors: Adrienne M. Bentley, Philipp D. Mayhew, William T. N. Culp, Cynthia M. Otto Tags: Original Study Source Type: research

Squamous Metaplasia of the Peritoneum: Report of a Case
This report presents a case of fully developed, mature peritoneal squamous metaplasia in an 85-year-old woman who underwent surgery because of small bowel perforation leading to diffuse peritonitis. This rare incidental finding almost always occurs in the background of chronic peritoneal irritation as a response to mesothelial injury. Squamos peritoneal metaplasia should not be interpreted as metastatic squamous cell carcinoma. The most important distinguishing criteria are the lack of nuclear atypia, mitoses, necrosis, and desmoplastic stromal response. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - January 13, 2013 Category: Pathology Authors: Mrklic, I., Bendic, A., Pogorelic, Z., Karaman, I., Glavina Durdov, M., Druzijanic, N., Tomic, S. Tags: Case Reports Source Type: research

Migration of Invariant Natural Killer T-Cells in Response To Peritonitis is Dependent Upon Direct Ligation of PD-1:PD-L1 on These Cells and Not Indirect Actions
Invariant Natural Killer T-cells (iNKT) serve as a bridge between the innate and acquired arms of the immune system and play an important role in sepsis/peritonitis. Sepsis leads to activation of both liver and circulating iNKT cells. When activated iNKT, cells express cell-associated ligand (called PD-L1) for the co-inhibitory protein called Programmed Death Receptor (PD)-1. We have previously shown that in the murine model of sepsis, cecal ligation and puncture (CLP), caused a decline in levels of iNKT in the liver, increasing levels of iNKT in the blood and peritoneum, which is likely indicative of iNKT cell exodus from...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: J.S. Young, C. Chung, W.G. Cioffi, A. Ayala, D.S. Heffernan Tags: Oral Session: Thursday 2/7 7:30 AM to 9:30 AM Source Type: research

Poor Outcome In Bacterial Peritonitis is Associated With Dysregulated MicroRNAs Resulting in an Increased Inflammatory Response
Peritonitis is a common cause of surgical sepsis. The inability of the host to clear the infection can result in persistent bacteria. The reasons for the failure of the immune response to clear the infection in some patients are unknown. We developed a model which mimics persistent bacterial peritonitis. MicroRNAs (miRNA) emerged as powerful modulators of the immune response. We hypothesize that miRNA contribute to this inadequate immune response. The purpose of this study is to investigate the potential role of miRNA on the immune responses of two clinically distinct populations. (Source: Journal of Surgical Research)
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: R.E. Barnett, R.C. Keskey, A.T. Billeter, W.G. Cheadle Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

EP1 Receptor Deficiency Protects Mice From Gut Barrier Breakdown During LPS-Induced Peritonitis
(Source: Journal of Surgical Research)
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S.S. Short, H.A. Ford, M. Zobel, J. Wang, S. Papillon, E.M. Pontarelli, B. Bell, A. Grishin, H.R. Ford Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Ethambutol/isoniazid/rifampicin: Tuberculous peritonitis in an elderly patient: case report
(Source: Reactions)
Source: Reactions - January 8, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Spontaneous bacterial peritonitis and pharmacologic acid suppression in patients with cirrhosis
(Source: Hepatology)
Source: Hepatology - January 8, 2013 Category: Internal Medicine Authors: Ruben Terg Tags: Hepatology Elsewhere Source Type: research

An unusual cluster of Acremonium kiliense fungaemias in a haematopoietic cell transplantation unit
We describe an unusual cluster of possible catheter-related bloodstream infections due to this pathogen in patients who underwent haematopoietic cell transplantation. (Source: Diagnostic Microbiology and Infectious Disease)
Source: Diagnostic Microbiology and Infectious Disease - January 7, 2013 Category: Microbiology Authors: Aliki Ioakimidou, Timoleon-Achilleas Vyzantiadis, Ioanna Sakellari, Michael Arabatzis, Christos Smias, Vassiliki Douka, Aristea Velegraki, Achilleas Anagnostopoulos, Nikolaos Malissiovas Tags: Case Reports Source Type: research

Systemic inflammation in absence of gut bacterial translocation in C57BL/6 mice with cirrhosis
We read with interest the article by Wiest et al about spontaneous bacterial peritonitis guidelines.1 The authors point out the relevance of pathological bacterial translocation (BT) from the gut to mesenteric lymph nodes (MLN) as the pathophysiological hallmark of spontaneous bacterial peritonitis in cirrhosis, and the need of further research in the factors involved in BT. The study of BT, ascites and related immune system abnormalities in carbon tetrachloride (CCl4) cirrhosis is usually conducted in rats. This model has proved useful for research into the pathogenesis and role of the systemic pro-inflammatory response a...
Source: Gut - January 4, 2013 Category: Gastroenterology Authors: Ubeda, M., Lario, M., Munoz, L., Diaz, D., Borrero, M. J., Garcia-Bermejo, L., Alvarez-Mon, M., Albillos, A. Tags: PostScript Source Type: research

Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)
Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes pat...
Source: World Journal of Emergency Surgery - January 3, 2013 Category: Emergency Medicine Authors: Massimo SartelliFausto CatenaLuca AnsaloniErnest MooreMark MalangoniGeorge VelmahosRaul CoimbraKaoru KoikeAri LeppaniemiWalter BifflZsolt BaloghCino BendinelliSanjay GuptaYoram KlugerFerdinando AgrestaSalomone di SaverioGregorio TugnoliElio JovineCarlos O Source Type: research

PAR-1 mediates the thrombin-induced mesothelial cell overproduction of VEGF and PAI-1.
Conclusions: HMC express PAR-1 and the receptor is involved in thrombin effects on these cells. These findings may be a basis for pharmacological prevention of neoangiogenesis and adhesions in the context of peritoneal dialysis and peritonitis. PMID: 23280079 [PubMed - as supplied by publisher] (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - January 2, 2013 Category: Transplant Surgery Authors: Belling F, Ribeiro A, Wörnle M, Ladurner R, Mussack T, Sitter T, Sauter M Tags: Int J Artif Organs Source Type: research

[Effects of Pseudomonas quinolone signal on the virulence of Pseudomonas aeruginosa].
CONCLUSION: PQS can maintain the adhesion and invasiveness of Pseudomonas aeruginosa, and in the hosts of the bacteria, PQS concentration is positively correlated with pyocyanin production and hence negatively with the survival time of the hosts. PMID: 23353148 [PubMed - in process] (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - January 1, 2013 Category: Universities & Medical Training Authors: Fu XH, Zhang XM, Jing CM, Liu L, Yin YB, Jiang JR Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

Intestinal perforation caused by insertion of a nasogastric tube late after gastric bypass.
Abstract A 57-year-old woman, who had undergone Roux-en-Y gastric bypass surgery 9 years earlier, was admitted to the intensive care unit because of pneumonia. Despite antibiotic therapy, she died 40 days later, apparently because of sepsis and organ failure related to the pneumonia. However, the patient's family requested an autopsy, which revealed that her death was due to perforation of the Roux limb of her gastric bypass, which had resulted in severe peritonitis. The perforation was caused by a nasogastric tube inserted for enteral nutrition. We discuss ways nasogastric tubes might be inserted more safely after...
Source: Baylor University Medical Center Proceedings - January 1, 2013 Category: Universities & Medical Training Authors: Van Dinter TG, John L, Guileyardo JM, John S F Tags: Proc (Bayl Univ Med Cent) Source Type: research

Nephrectomy Via Ventral Median Celiotomy in Equids
ConclusionsA ventral median approach for nephrectomy can be used for unilateral nephrectomy in equids weighing up to 434 kg. (Source: Veterinary Surgery)
Source: Veterinary Surgery - January 1, 2013 Category: Veterinary Research Authors: Carolyn E. Arnold, Tex Taylor, M. Keith Chaffin, Harold C. Schott, John P. Caron Tags: Original Article: Clinical Source Type: research

Cestode infection in 2 dogs: cytologic findings in liver and a mesenteric lymph node
Abstract Mesocestoides cestode infections in dogs are well known for causing severe peritonitis with larvae or larval fragments (metacestodes, tetrathyridia, or calcareous corpuscles) frequently observed cytologically in peritoneal fluid samples. This case report describes the cytologic and clinical features of 2 dogs infected with cestode larvae, with one case confirmed and the other presumed to be Mesocestoides sp. In these 2 unusual cases, cestode larvae or larval fragments were found in fine‐needle aspirates of the liver and a mesenteric lymph node, but no organisms were found in peritoneal fluid samples. The data pr...
Source: Veterinary Clinical Pathology - December 31, 2012 Category: Veterinary Research Authors: Penny K. Patten, Lon J. Rich, Karen Zaks, Melissa Blauvelt Tags: Case Report Source Type: research

Peritonitis Caused by Haemophilus parainfluenzae, Leifsonia aquatica, and Gordonia spp. in a Patient Undergoing Continuous Ambulatory Peritoneal Dialysis
Surgical Infections Dec 2012, Vol. 13, No. 6: 409-412. (Source: Surgical Infections)
Source: Surgical Infections - December 26, 2012 Category: Surgery Tags: article Source Type: research

Omentum patch substitute for facilitating endoscopic repair of GI perforations: an early laparoscopic pilot study with a foam matrix plug (with video)
Conclusion: The FMP offered a technically simple and feasible option for repairing iatrogenic gastric perforations. With effective sealing, the clinical outcome is similar to that of an omentum patch repair. Migration and inadequate sealing is a concern, which can lead to peritonitis and sepsis. Further development is needed to improve FMP performance. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - December 22, 2012 Category: Gastroenterology Authors: Eduardo A. Bonin, Juliane Bingener, Elizabeth Rajan, Mary Knipschield, Christopher J. Gostout Tags: Experimental Endoscopy Source Type: research

A soluble form of the CSF-1 receptor contributes to the inhibition of inflammation in a teleost fish.
Abstract We previously reported on the identification of a novel soluble form of the CSF-1 receptor (sCSF-1R) in goldfish that induced dose-dependent down-regulation of macrophage proliferation. Herein, we report that sCSF-1R has a role beyond macrophage development, which extends into the control of cellular antimicrobial inflammatory responses in this lower vertebrate. Using an in vivo model of self-resolving peritonitis coupled to in vitro characterization of sCSF-1R activity, we show that sCSF-1R plays a role in the inhibition of inflammation which follows an initial acute phase of innate antimicrobial response...
Source: Developmental and Comparative Immunology - December 20, 2012 Category: Allergy & Immunology Authors: Rieger AM, Konowalchuk JD, Havixbeck JJ, Robbins JS, Smith MK, Lund JM, Barreda DR Tags: Dev Comp Immunol Source Type: research

The effect of low glucose degradation product, neutral pH versus standard peritoneal dialysis solutions on peritoneal membrane function: the balANZ trial
Conclusions Biocompatible and conventional PD solutions exert differential effects on peritoneal small solute transport rate and UF over time. Adequately powered trials assessing the impact of these differential membrane effects on PD technique and patient survival rates are warranted. (Source: Nephrology Dialysis Transplantation)
Source: Nephrology Dialysis Transplantation - December 12, 2012 Category: Urology & Nephrology Authors: Johnson, D. W., Brown, F. G., Clarke, M., Boudville, N., Elias, T. J., Foo, M. W. Y., Jones, B., Kulkarni, H., Langham, R., Ranganathan, D., Schollum, J., Suranyi, M. G., Tan, S. H., Voss, D., on behalf of the balANZ Trial Investigators Tags: Intra- and Extracorporeal Treatments of Kidney Failure Source Type: research

A French national survey on the use of antibiotic prophylaxis in cirrhotic patients
ConclusionAntibiotic prophylaxis is well‐recognized by French practitioners but its routine use depends on the expertise of practitioners. Quinolones remain the main antibiotic class prescribed irrespective of the type of prophylaxis.© 2012 John Wiley & Sons A/S (Source: Liver International)
Source: Liver International - December 10, 2012 Category: Gastroenterology Authors: Thierry Thevenot, Thibault Degand, Natacha Grelat, Laure Elkrief, Camille Christol, Richard Moreau, Jean Henrion, Jean‐François Cadranel, Frances Sheppard, Christophe Bureau, Vincent Di Martino, Arnaud Pauwels, Tags: Original Articles Source Type: research

Familial mediterranean fever – an increasingly important childhood disease in Sweden
ConclusionsThe majority of patients with FMF present during childhood. The prevalence among immigrants in western Sweden is in the same range as in their country of origin. Time to diagnosis needs to be shortened by means of increased awareness of the disease. (Source: Acta Paediatrica)
Source: Acta Paediatrica - December 7, 2012 Category: Pediatrics Authors: P Wekell, V Friman, B Balci‐Peynircioglu, E Yilmaz, A Fasth, S Berg Tags: Regular Article Source Type: research