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This page shows you the latest news and research items in this category.

J&J plans filing on more than 10 new drugs by 2017
(Reuters) - Johnson & Johnson said on Thursday it plans to submit more than 10 new products for regulatory approval by 2017, including drugs to treat hepatitis C, immune diseases and schizophrenia, and vaccines for flu, rabies and polio. (Source: Reuters: Health)
Source: Reuters: Health - May 23, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Modified Polio Virus May Help Fight Brain Tumors, Study Suggests
Treatment is harmless to normal cells but attacks cancer cells; finding is preliminary, researchers say (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - May 23, 2013 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Infections, Oncology, Research, News, Source Type: news

Peptide profiling of the route from Mahoney to Sabin, and return
Abstract In order to define poliovirus (PV) neurovirulence at the molecular level, we comparatively analyze the primary amino acid sequence of Mahoney, a neurovirulent PV strain, versus (i) Sabin, an attenuated PV strain, and (ii) IS1, a PV isolate obtained in temporal association to a paralysis event from a polio vaccinated subject. We identify and describe 12 pentapeptides that, originally present in the Mahoney sequence, are changed in the non‐neurovirulent Sabin strain, and, successively, restored in IS1 strain. (Source: Journal of Basic Microbiology)
Source: Journal of Basic Microbiology - May 20, 2013 Category: Microbiology Authors: Darja Kanduc, Candida Fasano, Simona Lucia Bavaro, Giuseppe Novello, Guglielmo Lucchese, Giovanni Capone Tags: Research Paper Source Type: research

Performance and determinants of routine immunization coverage within the context of intensive polio eradication activities in Uttar Pradesh, India: Social Mobilization Network (SM Net) and Core Group Polio Project (CGPP)
Routine polio immunization coverage in Uttar Pradesh has increased concurrently with intensive polio eradication activities, suggesting that polio eradication efforts do not interfere with routine immunization, and that targeted health communications can improve routine immunization performance. (Source: BMC International Health and Human Rights)
Source: BMC International Health and Human Rights - May 16, 2013 Category: Global & Universal Authors: William WeissManojkumar ChoudharyRoma Solomon Source Type: research

NanoPass Technologies Supports A CDC-Sponsored Phase 3 Study Of Polio Vaccine In Infants As Part Of its Global Health Initiative
NanoPass Technologies Ltd. ("NanoPass"), a pioneer in intradermal (into-the-skin or ID) vaccine delivery solutions, is collaborating with the US Center of Disease Control and prevention (CDC) in conducting a large phase 3 trial of polio vaccine in infants inSouth East Asia. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - May 14, 2013 Category: Pharmaceuticals Source Type: news

Nigeria: Kaduna Immunises 3 Million Children Against Polio Monthly
[Daily Trust]Kaduna -Executive Secretary of the Kaduna State Primary Health Care Agency, Dr. Sufiyan M. Babale, has said that since January this year, the state has been immunizing over three million children in its monthly Immunization Plus Days (IPDs) campaign. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - May 14, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Canada Invests U.S.$18 Million On Polio Eradication in Nigeria
[Daily Trust]The Canadian International Development Agency (CIDA) has allocated $18 million to polio eradication in Nigeria through a grant that will support surveillance and response system, increase targeted polio vaccination campaigns and strengthen the routine immunization system. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - May 14, 2013 Category: Infectious Diseases Source Type: news

Angola: Vaccination Against Polio Continues This Week
[ANGOP]Luanda -The vaccination of children under five years, in Luanda, will continue until next weekend, in order cover all the little ones, it was learned, Monday. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - May 14, 2013 Category: Infectious Diseases Source Type: news

Modeling the effects of immunizations timing on child health outcomes in india
SUMMARY Timely vaccinations of children in developing countries are important for reducing morbidity and mortality, which are Millennium Development Goals. However, a majority of children do not possess vaccination cards compiling information on timing. We investigated the benefits of vaccination cards for the uptake of immunizations against diphtheria, pertussis and tetanus (DPT), polio, tuberculosis (BCG), and measles using data on over 200,000 Indian children from the District Level Health and Facility Survey 3. Methodological issues such as whether parents of children with higher morbidity levels may have them vaccinat...
Source: Health Economics - May 14, 2013 Category: Health Management Authors: Alok Bhargava, Aravinda M. Guntupalli, Michael Lokshin, Larry L. Howard Tags: Research Article Source Type: research

Nigeria: Niger, Kano Records Two Polio Cases
[Daily Trust]Kaduna -Two cases of Wild Polio Virus had been recorded in Tafa Local Government Area of Niger and Fagge in Kano respectively, Executive Secretary of Kaduna State Primary Health Care Agency, Dr. Sufiyan M. Babale has said. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - May 13, 2013 Category: Infectious Diseases Source Type: news

Nigeria: 'No New Case of Polio in Niger'
[Daily Trust]Minna -Executive Director of the Niger State Primary Health Care Development Agency (NSPHCDA) Dr. Aliyu Mohammed has described the claim of the emergence of a new case of wild polio virus in the state as untrue. He said the discovery of a new case of polio was made in the Federal Capital Territory. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - May 13, 2013 Category: Infectious Diseases Source Type: news

Angola: Polio Immunization Campaign to Reach Two Million Children
[ANGOP]Luanda -Two million children under five years of age will be immunized in Luanda during the vaccination campaign against polio started Friday and scheduled to end on Sunday, 12. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 11, 2013 Category: African Health Source Type: news

Vaccines to be juggled in final assault against polio
The WHO is beginning what it hopes will be its final push to eradicate polio, involving the fastest, largest roll-out of a vaccine in history (Source: New Scientist - Health)
Source: New Scientist - Health - May 10, 2013 Category: Consumer Health News Source Type: research

Nigeria: Medical Experts Unveil U.S.$5.5 Billion Polio Eradication Plan
[This Day]Abuja -An international agency, Global Health Strategies (GHS), has declared that total eradication of polio-myelitis is possible by 2018, if the $5.5 billion global intervention fund can be achieved. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - May 9, 2013 Category: Infectious Diseases Source Type: news

Distal Femoral Fractures in Post‐poliomyelitis Patients Treated with Locking Compression Plates
ConclusionsLCP provides stable fixation of distal femoral fractures in post‐polio patients. Bony union and good functional outcomes are achieved, but delayed union and minimal callus may occur. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - May 9, 2013 Category: Orthopaedics Authors: Wei‐jun Wang, Hong‐fei Shi, Dong‐yang Chen, Yi‐xin Chen, Jun‐fei Wang, Shou‐feng Wang, Yong Qiu, Jin Xiong Tags: CLINICAL ARTICLE Source Type: research

Nigeria: World Leaders Pledge to End Polio By 2018
[Vanguard]A comprehensive six year plan to end polio through strengthening immunisation systems and vaccinating one billion children has been presented by the Global Polio Eradication Initiative, GPEI. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - May 7, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Experts Endorse New Strategy to End Polio by 2018
[Daily Trust]Kaduna -Over 400 global experts from 80 countries have endorsed a new comprehensive eradication strategy to secure a lasting polio-free world by 2018. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - May 6, 2013 Category: Infectious Diseases Source Type: news

Infections and cancer: debate about using vaccines as a cancer control tool
In 2012, Infectious Agents and Cancer commissioned a thematic series collection of articles on Prevention of HPV related cancer. The articles have attracted wide interest and stimulated debate, including about the utility of vaccines in cancer control. The application of vaccines to cancer control fulfills a promise envisioned at the turn of the 20th century when remarkable experiments showed that some cancers were caused by infections. This suggested the possibility of applying infection-control strategies to cancer control. Vaccines represent the most practical cost-effective technology to prevent wide human suffering an...
Source: Infectious Agents and Cancer - May 4, 2013 Category: Cancer & Oncology Authors: Sam MbulaiteyeFranco Buonaguro Source Type: research

[Comment] Poliomyelitis in Pakistan: time for the Muslim world to step in
Global poliomyelitis eradication is almost within reach—this disease persists only in Nigeria, Afghanistan, and Pakistan, which are countries with substantial Muslim populations. Today this ambitious goal is threatened, partly by misinformed and politicised religious views that not only seed suspicion about polio vaccination but recently led to murder of polio workers. In Pakistan, 16 workers engaged in a polio vaccination campaign have been killed since December, 2012, halting vaccination in many parts of the country and placing Pakistan's 2012 gains in poliomyelitis eradication at risk. (Source: LANCET)
Source: LANCET - May 4, 2013 Category: Journals (General) Authors: Qanta A Ahmed, Sania Nishtar, Ziad A Memish Tags: Comment Source Type: research

Progress Toward Eradication of Polio — Worldwide, January 2011–March 2013
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - May 3, 2013 Category: American Health Source Type: news

Intensity of crisis unabated, lifesaving care amidst insecurity difficult
The conflict in Syria is extremely intense, with moving front lines, enclaves of people cut off from assistance, an estimated 6.8 million people in urgent need of humanitarian assistance and a collapsed health system. Despite the very real challenges of operating in the country, Médecins Sans Frontières (MSF) now has four hospitals, increasing mobile clinic activities around some of these hospitals, and a strategy of actively seeking to open new projects where it is safe to do so. In order to be entirely independent of all political positioning around the Syria crisis, MSF only uses private donations for its work in Syri...
Source: MSF News - May 3, 2013 Category: Global & Universal Tags: Syria Frontpage NEWS Violence Source Type: news

[News & Analysis] Newsmaker Interview: Bill and Melinda Gates Talk Science
Philanthropists Bill and Melinda Gates chat with Science, mostly about two of their passions: eradicating polio worldwide by 2018 and getting modern contraceptives to another 120 million women by 2020.Author: Leslie Roberts (Source: Science: Current Issue)
Source: Science: Current Issue - May 3, 2013 Category: Science Authors: Leslie Roberts Source Type: research

Progress toward eradication of polio - worldwide, january 2011-march 2013.
This report provides an update on progress toward global polio eradication during January 2011-March 2013, using data reported as of April 23, 2013. The number of WPV cases reported globally decreased 66%, from 650 in 2011 to 223 in 2012; WPV cases decreased 53% (from 80 to 37) in Afghanistan and 71% (from 198 to 58) in Pakistan, but increased 97% (from 62 to 122) in Nigeria. The number of imported WPV cases in previously polio-free countries decreased from 309 in 12 countries in 2011 to six in two countries in 2012 (3,4). During January-March 2013, a total of 22 WPV cases were reported worldwide, compared with 48 cases du...
Source: MMWR Morb Mortal Wkl... - May 3, 2013 Category: Epidemiology Authors: Centers for Disease Control and Prevention (CDC) Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Haemophilus influenzae Type b in an Immunocompetent, Fully Vaccinated ALL Survivor
A 7-year-old boy with a history of recurrent acute lymphoblastic leukemia (ALL), in remission, presented to primary care clinic after 2 days of progressive right hip pain with weight-bearing activities. He was otherwise asymptomatic at the time of presentation. Blood cultures revealed Gram-negative diplococci, which prompted an MRI that was significant for a hip joint effusion and femoral head bone marrow edema. The patient had no sick contacts and no significant past medical history other than ALL. The patient had been given all recommended childhood vaccinations. Arthrocentesis and needle biopsy of the femoral neck were ...
Source: PEDIATRICS - May 1, 2013 Category: Pediatrics Authors: Nevin, J., Kanter Washko, J., Arnold, J. Tags: Case Report Source Type: research

Anti-poliovirus activity of protease inhibitor AG-7404, and assessment of in vitro activity in combination with antiviral capsid inhibitor compounds.
Abstract The National Research Council has recommended that at least one, preferably two, polio antiviral drugs be developed as a supplement to the tools currently available for control of polio outbreaks post-eradication. The primary application of such drugs is expected to be the resolution of chronic poliovirus excretion in persons with primary immunodeficiency disorders. We have assessed the in vitro activity of AG-7404 (also known as "compound 1"), an inhibitor of picornaviral 3C protease, against a large panel of programmatically important poliovirus strains and its activity in combination with two poliovirus...
Source: Antiviral Research - May 1, 2013 Category: Virology Authors: Rhoden E, Liu HM, Wang-Chern SW, Oberste MS Tags: Antiviral Res Source Type: research

South Africa: Gauteng Health Embarks On Polio and Measles Campaign
[SA Govt]This morning, more than 100 children under the age of five received their first dose of polio drops and measles vaccine at Thusanang Daycare Centre in Muldersdrift, West Rand. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 30, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Polio Eradication - What Progress So Far?
[Daily Trust]Jos -The 3rd African Vaccination Week (AVW), organized by the African Region of World Health Organization (WHO) April 22 to 28, 2013, came under the theme, 'Save Lives. Prevent disabilities. Vaccinate', and accomplished heightened continent-wide awareness of the place of routine immunization against vaccine-preventable diseases. All 46 member-states of WHO in the African region participated in efforts to strengthen immunization programmes around the continent against diphtheria, haemophilus influenzae serotype (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 30, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Tomori Tasks President Jonathan On Polio Eradication
[Vanguard]As Nigeria battles rejection of polio vaccination in the North, renowned Virologist, Professor Oyewale Tomori has alleged that Nigerian leaders are yet to show enough commitment needed to attain the global eradication deadline by 2018. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 30, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Sultan Urges Parents to Embrace Immunisation Against Polio
[Vanguard]Sokoto -The Sultan of Sokoto, Alhaji Sa'ad Abubakar 111, has appealed to parents in the North to allow their children to be immunised with the polio vaccine. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 30, 2013 Category: Infectious Diseases Source Type: news

South Africa: National Measles and Polio Mass Campaign 2013
[SA Govt]The National Polio and Measles and Polio Campaign takes place annually: (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 29, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Polio Vaccine Is Safe, Sultan Reassures
[Premium Times]The Sultan of Sokoto, Sa'ad Abubakar, has appealed to parents to allow their children be immunised with the polio vaccine, saying it is safe to be vaccinated. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 29, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Global Leaders Pledge to Boost Polio Eradication Drive
[Daily Trust]Jos -Global leaders have pledged their support for a new six-year plan to deliver a polio-free world by 2018, the United Nations Children's Fund (UNICEF) has indicated. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 29, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Misrepresentation of My Position in Polio Controversy (II)
[Daily Trust]To reinforce his argument, Aliyu reported yet another OPV test by the trio of "Professor Emeritus Umaru Shehu, foremost public health consultant who was the first chairman of the National Programme on Immunization (NPI), Professor Herbert Coker, a pharmaceutical scientist and chemist from the University of Lagos and Dr Rafindadi led the federal government delegation to South Africa in November 2003 with 96 samples of the Oral Polio Vaccines (OPV)"; and these eminent personalities had discovered the samples (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 29, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Stop Preaching Against Polio Immunization, Pate Tells Islamic Clerics
[This Day]The Minister of State for Health, Dr. Muhammad Ali Pate, Sunday appealed to Islamic clerics in the North who have been preaching against polio immunisation to desist forthwith in the interest of the health of the children in the region. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 29, 2013 Category: Infectious Diseases Source Type: news

Africa: UN-Backed Global Vaccine Summit Aims to Boost Efforts to Eliminate Polio
[UN News]Polio eradication efforts are the focus of the United Nations-backed Global Vaccine Summit which also aims to protect millions of children from diseases like measles and tetanus through inoculations. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 26, 2013 Category: Infectious Diseases Source Type: news

South Sudan: South Sudan Prioritizes Immunization, Keeps Polio At Bay
[IRIN]Juba -Through frequent door-to-door polio immunization campaigns, South Sudan has vaccinated more than 94 percent of children under age five against the disease, according to the Ministry of Health. The immunization effort has been one of the country's few health success stories since it achieved independence a year and a half ago. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 26, 2013 Category: Infectious Diseases Source Type: news

Africa: Global Leaders Support New Six-Year Plan to Deliver a Polio-Free World by 2018
[Unicef]Abu Dhabi, United Arab Emirates -Pledges announced will enable more than 2.7 billion children to be vaccinated (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 26, 2013 Category: Infectious Diseases Source Type: news

New USD 5.5 Billion Plan Aims to Rid World of Polio by 2018New USD 5.5 Billion Plan Aims to Rid World of Polio by 2018
Health groups said could rid the world of polio by 2018 with a $5.5 billion vaccination and monitoring plan to stop the disease taking hold once more now there are only a handful of cases worldwide. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 25, 2013 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

FDA Contributing to Fight Against Polio
This is World Immunization Week and FDA is working global partners to make safe and effective vaccines available all over the world. In particular, FDA has joined the fight to ride the world of polio, which still exists in some parts of the world. (Source: FDA Consumer Updates)
Source: FDA Consumer Updates - April 25, 2013 Category: Consumer Health Advice Source Type: news

New $5.5 billion plan aims to rid world of polio by 2018
LONDON (Reuters) - Health groups said on Thursday they could rid the world of polio by 2018 with a $5.5 billion vaccination and monitoring plan to stop the disease taking hold once more now there are only a handful of cases worldwide. (Source: Reuters: Health)
Source: Reuters: Health - April 25, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Global leaders support new six-year plan to deliver a polio-free world by 2018
25 April 2013 – Today, at the Global Vaccine Summit, the Global Polio Eradication Initiative (GPEI) presented a comprehensive six-year plan, the first plan to eradicate all types of polio disease – both wild poliovirus and vaccine-derived cases – simultaneously. Global leaders and individual philanthropists signaled their confidence in the plan by pledging close to three-quarters of the plan’s projected US$ 5.5 billion cost over six years. (Source: WHO news)
Source: WHO news - April 25, 2013 Category: Global & Universal Source Type: news

UN-backed Global Vaccine Summit aims to boost efforts to eliminate polio and other diseases
Polio eradication efforts are the focus of the United Nations-backed Global Vaccine Summit which also aims to protect millions of children from diseases like measles and tetanus through inoculations. (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - April 25, 2013 Category: Global & Universal Source Type: news

Nigeria: Seizing the Chance to Make Polio History
[This Day]The battle against polio is an extraordinary example of what can be achieved when we work together. This terrible disease, as my generation knows well,once cast a shadow over childhood across the world. Before the development of an effective vaccine nearly 60 years ago, it paralyzed and killed up to half a million people every year. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 24, 2013 Category: Infectious Diseases Source Type: news

A Polio-Free U.S. Thanks to Vaccine Efforts
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - April 24, 2013 Category: Journals (General) Source Type: news

Nigeria: 1,000 Polio Cases Caused By Misinformation - Minister
[Daily Trust]The Minister of State for Health, Dr Muhammad Pate, has expressed shock that more than 1,000 children have been paralysed by the wild polio virus largely due to the rejection of immunisation in the northern part of the country. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 23, 2013 Category: Infectious Diseases Source Type: news

Polio-Free U.S. Thanks to Vaccine Efforts
Source: Centers for Disease Control and Prevention Related MedlinePlus Pages: Polio and Post-Polio Syndrome, Traveler's Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 22, 2013 Category: Consumer Health News Source Type: news

Lessons from Smallpox Guide Polio Endgame
The world is closer than ever to eradicating polio. With only 223 wild poliovirus cases in five countries in 2012, the paralytic disease has been knocked down to just a handful of small reservoirs. Recognizing this historic opportunity to achieve eradication, we have enthusiastically joined more than 400 scientists from 80 countries to sign the Scientific Declaration on Polio Eradication . Through the declaration, we are endorsing a clear path--not just an aspiration--to bring an end to polio: the new Eradication and Endgame Strategic Plan . This plan, developed by polio partners, donors and other stakeholders under the ...
Source: Scientific American - Official RSS Feed - April 22, 2013 Category: Science Tags: Health,More Science Source Type: research

Nigeria: Katsina Is Polio Free - PHCDA
[Daily Trust]THE Katsina State Primary Healthcare Development Agency (PHCDA) has said the state is now free from all cases of polio. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 22, 2013 Category: Infectious Diseases Source Type: news

Nigeria: Polio - Intimidation Can Only Boomerang
[Daily Trust]One thing that regularly recurs in the story of Holocaust deniers is the fact that they were forced to deny the dubious historical event by the sheer weight of intimidation that visited all those who had questioned the Holocaust before them. In these days of freedoms of speech and expression as well as some extreme forms of human rights; such as the right to satanic gay marriages, it is amazing that questioning a simple historical reality (or is it fiction?) could invite the wrath of state establishments a (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 22, 2013 Category: Infectious Diseases Source Type: news

Gulf backing sought for polio eradication
Abu Dhabi officials join European, African and Asian politicians at a global summit as they seek to find a further $2.5bn to fund intensified vaccination (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - April 22, 2013 Category: Pharmaceuticals Source Type: news