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Parent Training Complements Medication for Treating Behavioral Problems in Children with Pervasive Developmental Disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Treatment that includes medication plus a structured training program for parents reduces serious behavioral problems in children with autism and related conditions, according to a study funded by the National Institute of Mental Health (NIMH). The study, which was part of the NIMH Research Units on Pediatric Psychopharmacology (RUPP) Autism Network, was published in the December 2009 issue of the Journal of the American Academy of Child and Adolescent Psychiatry. (Source: National Institute of Mental Health)
Source: National Institute of Mental Health - November 21, 2009 Category: Psychiatry Authors: National Institute of Mental Health Source Type: organizations

Lp-PLA2 could predict vascular events in elderlyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Lipoprotein-associated phospholipase A2 may be a potential biomarker for vascular events in the elderly, a study suggests. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 21, 2009 Category: Lipidology Source Type: news

Dynamic and spectroscopic characteristics of atmospheric gliding arc in gas-liquid two-phase flowemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study, an atmospheric alternating-current gliding arc device in gas-liquid two-phase flow has been developed for the purpose of waste water degradation. The dynamic behavior of the gas-liquid gliding arc is investigated through the oscillations of electrical signals, while the spatial evolut ... [Phys. Plasmas 16, 113506 (2009)] published Fri Nov 20, 2009. (Source: Physics of Plasmas)
Source: Physics of Plasmas - November 21, 2009 Category: Physics Source Type: journals

Failure of thermocapillary-driven permanent nonwetting dropletsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study, we exploit thermocapillary convection, caused by a temperature difference maintained between the droplet and the unw ... [Phys. Fluids 21, 112106 (2009)] published Fri Nov 20, 2009. (Source: Physics of Fluids)
Source: Physics of Fluids - November 21, 2009 Category: Physics Source Type: journals

Photoelectron spectroscopy study of systematically varied doping concentrations in an organic semiconductor layer using a molecular p-dopantemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
S. Olthof, W. Tress, R. Meerheim, B. Lussem, and K. Leo We investigate the doping behavior of the strongly electron accepting molecule 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane coevaporated with the host molecule N,N,N,N-tetrakis(4-methoxyphenyl)-benzidine by photoemission spectroscopy and conductivity measurements. Using interface resolved me ... [J. Appl. Phys. 106, 103711 (2009)] published Fri Nov 20, 2009. (Source: Journal of Applied Physics)
Source: Journal of Applied Physics - November 21, 2009 Category: Physics Source Type: journals

Short- and long-range orders in FeCr: A Monte Carlo studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
C. Pareige, C. Domain, and P. Olsson Atomistic kinetic Monte Carlo simulations based on the two-band semiempirical cohesive model for FeCr have revealed a body centered tetragonal FeCr ordered compound at very low temperatures. Density functional theory calculations have shown that this structure is more stable than the FeCr compound r ... [J. Appl. Phys. 106, 104906 (2009)] published Fri Nov 20, 2009. (Source: Journal of Applied Physics)
Source: Journal of Applied Physics - November 21, 2009 Category: Physics Source Type: journals

Comparison of amorphous silicon photodiodes and photoconductors for detection of quantum dot biomolecular tagsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A. C. Pimentel, D. M. F. Prazeres, V. Chu, and J. P. Conde A comparative study of the performance of hydrogenated amorphous silicon photosensors based on two different device configurations for integration in a microarray platform for biomolecular detection is presented. A perpendicular contact p-i-n photodiode and a parallel contact intrinsic photoconducto ... [J. Appl. Phys. 106, 104904 (2009)] published Fri Nov 20, 2009. (Source: Journal of Applied Physics)
Source: Journal of Applied Physics - November 21, 2009 Category: Physics Source Type: journals

Effect of the anisotropy distribution on the coercive field and switching field distribution of bit patterned mediaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present a systematic study on the magnetization reversal in square arrays of magnetic nanostructures. To account for the unavoidable inhomogeneities of the magnetic properties due to, i.e., template preparation, a distribution of magnetic anisotropy values was taken into account. We show that the ... [J. Appl. Phys. 106, 103913 (2009)] published Fri Nov 20, 2009. (Source: Journal of Applied Physics)
Source: Journal of Applied Physics - November 21, 2009 Category: Physics Source Type: journals

Electronic characteristics of the interfacial states embedded in buffer-free GaSb/GaAs (001) heterojunctionsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report a comprehensive study of the electronic properties and compensation of the interfacial states embedded in a majority carrier electron region either on one or both sides of the buffer-free GaSb/GaAs (001) heterointerface. An abrupt change observed in the forward-bias current (58 mA) for a s ... [Appl. Phys. Lett. 95, 202107 (2009)] published Fri Nov 20, 2009. (Source: Applied Physics Letters)
Source: Applied Physics Letters - November 21, 2009 Category: Physics Source Type: journals

Study of an organic-inorganic hybrid columinescence system by photoacoustic methodemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Yue-tao Yang, Xiao-jun Liu, and Shu-yi Zhang In this work, a columinescence system is found for lanthanide complexes Ln(p-ABA)HO (p-ABA: p-aminobenzoic acid) incorporated in silica matrix. It is found that the luminescence quantum yield of Tb emissions increases remarkably when partly replacing Tb(p-ABA)HO by Gd(p-ABA)HO in silica glass. Moreo ... [Appl. Phys. Lett. 95, 201115 (2009)] published Fri Nov 20, 2009. (Source: Applied Physics Letters)
Source: Applied Physics Letters - November 21, 2009 Category: Physics Source Type: journals

Why can't some people give up cocaine?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Drug dependency is a recurrent but treatable kind of addiction. However, not all people who are drug dependent progress in the same way once they stop taking drugs. A new study shows that, in the case of cocaine, a high score on the so-called ‘scale of craving’, an antisocial personality type and previous heroin abuse are the factors most commonly involved in people falling back into the habit. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 21, 2009 Category: Science Source Type: news

Older problem drinkers use more alcohol than do their younger counterpartsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Older adults who have alcohol dependence problems drink significantly more than do younger adults who have similar problems, a new study has found. The findings suggest that older problem drinkers may have developed a tolerance for alcohol and need to drink even more than younger abusers to achieve the effects they seek. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 21, 2009 Category: Science Source Type: news

Hidden threat: Elevated pollution levels near regional airportsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Scientists are reporting evidence that air pollution -- a well-recognized problem at major airports -- may pose an important but largely overlooked health concern for people living near smaller regional airports. Those airports are becoming an increasingly important component of global air transport systems. The study, one of only a handful to examine airborne pollutants near regional airports, suggests that officials should pay closer attention to these overlooked emissions, which could cause health problems for local residents. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 21, 2009 Category: Science Source Type: news

Barn personnel experience higher-than-average rates of respiratory symptomsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The estimated 4.6 million Americans involved in the equine industry may be at risk of developing respiratory symptoms due to poor air quality in horse barns, according to a questionnaire study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 21, 2009 Category: Science Source Type: news

Mother’s Depression a Risk Factor in Childhood Asthma Symptoms, Study Suggests-11/19/09email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Asthma symptoms can worsen in children with depressed mothers, according to research from Johns Hopkins Children’s Center published online in the Journal of Pediatric Psychology. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - November 21, 2009 Category: Research Source Type: news

Cause of Death? Lack of Insuranceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Nov. 20, 2009 - The lack of health insurance is associated with nearly 45,000 deaths annually in the United States, the only industrialized nation without universal health care, according to a new study from researchers at Harvard University in Boston. Other studies have found increased mortality rates among the uninsured, as well, even in trauma situations. (Source: NurseZone.com Featured Stories)
Source: NurseZone.com Featured Stories - November 21, 2009 Category: Nursing Source Type: info

Coiling for very small aneurysms ‘feasible and effective’email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Endovascular treatment of very small intracranial aneurysms is feasible and effective in more than 90% of cases, a meta-analysis of seven published studies suggests. (Source: MedWire News - Stroke)
Source: MedWire News - Stroke - November 21, 2009 Category: Neurology Source Type: news

Prevalence of prothrombotic polymorphisms in a selected cohort of cryptogenic and noncryptogenic ischemic stroke patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study population under 55 years of age there was no significant difference in the prevalence of various genetic polymorphisms, factor V, prothrombin, 5,10-methylenetetrahydrofolate reductase, plasminogen activator inhibitor-1, and human platelet alloantigens) in patients with cryptogenic ischemic stroke and in patients with ischemic stroke of determined cause. (Source: Neurology India)
Source: Neurology India - November 21, 2009 Category: Neurology Authors: Calabro Rocco Salvatore, La Spina Paolino, Serra Salvatore, Lagana Angelina, Postorino Paolo, Savica Rodolfo, Mammi Corrado, Lagana Carmelo, Musolino Rosa Source Type: journals

Early H. pylori eradication protects peptic ulcer patients against gastric canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Early helicobacter pylori eradication reduces the risk for gastric cancer in patients with peptic ulcer disease, study findings show. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - November 21, 2009 Category: Gastroenterology Source Type: news

Green Tea Catechins: Inhibitors of Glycerol-3-Phosphate Dehydrogenaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Planta MedDOI: 10.1055/s-0029-1240623AbstractGreen tea catechins, especially (−)-epigallocatechin-3-gallate (EGCG), are known to regulate obesity and fat accumulation. We performed a kinetic analysis in a cell-free system to determine the mode of inhibition of glycerol-3-phosphate dehydrogenase (GPDH; EC 1.1.1.8) by EGCG. GPDH catalyzes the -nicotinamide adenine dinucleotide (NADH)-dependent reduction of dihydroxyacetone phosphate (DHAP) to yield glycerol-3-phosphate, which serves as one of the major precursors of triacylglycerols. We found that EGCG dose-dependently inhibited GPDH activity at a concentration of appr...
Source: Planta Medica - November 21, 2009 Category: Drugs & Pharmacology Tags: Letters Source Type: journals

Intestinal and Blood-Brain Barrier Permeability of Ginkgolides and Bilobalide: In Vitro and In Vivo Approachesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study intestinal and blood-brain barrier (BBB) permeability of ginkgolides A, B, C, J and bilobalide, isolated from (Ginkgoaceae), was evaluated in Caco-2 and MDR1-MDCK cell monolayer models. The transport was examined for 2 hours in both absorptive and secretory directions. Quantitation was performed by UPLC‐MS. In the Caco-2 model, each compound (100 µM) displayed a pH-dependent transport in the absorptive direction. A low permeability of ginkgolides was observed across the MDR1-MDCK model in the absorptive direction. An efflux was observed for all compounds in both the models. The efflux ratio was m...
Source: Planta Medica - November 21, 2009 Category: Drugs & Pharmacology Tags: Original Papers Source Type: journals

Administration of Caffeic Acid Worsened Bone Mechanical Properties in Female Ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, high intake of caffeic acid may unfavorably affect the skeletal system.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents  |  Abstract  |  Full text (Source: Planta Medica)
Source: Planta Medica - November 21, 2009 Category: Drugs & Pharmacology Tags: Original Papers Source Type: journals

Stunts Raise Injury Risks for Cheerleadersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Type of flooring, greater heights increase potential for trauma, study finds (Source: Forbes.com Health News)
Source: Forbes.com Health News - November 21, 2009 Category: Consumer Health News Source Type: news

Analysis of Factors Influencing Outcome in Patients With In-Transit Malignant Melanoma Undergoing Isolated Limb Perfusion Using Modern Treatment Parametersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this single-center study of 91 patients with stage III in-transit extremity melanoma, operative isolated limb perfusion (ILP) was associated with high response rates and long-term survival. ILP treatment... Access... (Source: OncologySTAT Journal Scans)
Source: OncologySTAT Journal Scans - November 21, 2009 Category: Cancer & Oncology Source Type: journals

IL-6 overexpression plus androgen withdrawal could reduce prostate cancer growthemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Overexpression of interleukin-6 in prostate cancer cells enhances their sensitivity to androgen withdrawal both in vitro and in vivo, say researchers who claim their study is the first to demonstrate the association. (Source: MedWire News - Prostate Cancer)
Source: MedWire News - Prostate Cancer - November 21, 2009 Category: Cancer & Oncology Source Type: news

IL-6 overexpression plus androgen withdrawal could reduce prostate cancer growthemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Overexpression of interleukin-6 in prostate cancer cells enhances their sensitivity to androgen withdrawal both in vitro and in vivo, say researchers who claim their study is the first to demonstrate the association. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - November 21, 2009 Category: Cancer & Oncology Source Type: news

Health headlines: Fearless toddlers, Viagra for kids and Santa wants his vaccineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Other stories we’ve been reading: A new study says your child is more likely to become a criminal if they don’t have good fear conditioning. Pediatricians are ordering Viagra for children with heart defects. A new report says too much food, not a lack of exercise, is to blame for teen obesity, and researchers find that toddlers and obese kids suffer the most from secondhand smoke. More kids’ lives are saved as the cost of child vaccines fall and Santa says he wants his H1N1 vaccine too. Related posts:Health headlines: More H1N1 news, Down syndrome and smart phones for toddlersHealth headlines: H1N1 news, yoga for ...
Source: Thrive, Children's Hospital Boston - November 21, 2009 Category: Pediatrics Authors: Children's Hospital Boston staff Tags: All posts eating well flu Flu vaccine h1n1 health headlines nutrition obesity secondhand smoke swine flu swine flu vaccine teen health teenagers unhealthful eating Vaccines Viagra Source Type: organizations

Did Philippe Pinel frame the concept of the disease rheumatoid arthritis in the year 1800?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The dissertation from 1800 by Landré-Beauvais (LB) is quoted as an early description of rheumatoid arthritis (RA) with the implication that the disease was new at that time. However, physicians of the past may not have been able to perceive an already existing disease due to a lacking concept of it. The dissertation has been studied in the context of contemporary medical literature, modern historical and biographical texts. LB's dissertation seems to have been influenced by LB's mentor Philippe Pinel. The present study does not permit to conclude whether RA was a new disease. PMID: 19922026 [PubMed - as suppli...
Source: Scandinavian Journal of Rheumatology - November 21, 2009 Category: Rheumatology Authors: Hansen S Tags: Scand J Rheumatol Source Type: journals

Financial compensation and vocational recovery: a prospective study of secondary care neck and back patients.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: In employed patients, a claim for financial compensation for low back or neck pain with radiating pain was found to be independently associated with receipt of income compensation benefits after 1, 3, and 5 years. PMID: 19922025 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)
Source: Scandinavian Journal of Rheumatology - November 21, 2009 Category: Rheumatology Authors: Hestbaek L, Rasmussen C, Leboeuf-Yde C Tags: Scand J Rheumatol Source Type: journals

The use of complementary and alternative medicine in outpatients with inflammatory rheumatic diseases in Sweden.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: CAM use is widespread among rheumatology patients in Sweden. A total of 65% of the patients had experience of CAM treatment. Female sex, younger age, and poor health were associated with CAM utilization. PMID: 19922024 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)
Source: Scandinavian Journal of Rheumatology - November 21, 2009 Category: Rheumatology Authors: Klingberg E, Wallerstedt S, Torstenson T, Håwi G, Forsblad-d'Elia H Tags: Scand J Rheumatol Source Type: journals

Aberrant expression pattern of histone acetylation modifiers and mitigation of lupus by SIRT1-siRNA in MRL/lpr mice.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: An aberrant expression pattern of HATs and HDACs exists in CD4+ T cells of MRL/lpr mice, among which SIRT1 overexpression is implicated in lupus pathogenesis and SIRT1-siRNA mitigates the damage of lupus in vivo in MRL/lpr mice. PMID: 19922023 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)
Source: Scandinavian Journal of Rheumatology - November 21, 2009 Category: Rheumatology Authors: Hu N, Long H, Zhao M, Yin H, Lu Q Tags: Scand J Rheumatol Source Type: journals

An epidemiological survey of low back pain and axial spondyloarthritis in a Chinese Han population.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The survey questionnaire for SpA in this study is useful for axial SpA screening in China. In southern China, the prevalence of LBP is 7.21%. The prevalence of axial SpA is 0.782%. USpA is the most common subtype of SpA, followed by AS. PMID: 19922021 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)
Source: Scandinavian Journal of Rheumatology - November 21, 2009 Category: Rheumatology Authors: Liao Z, Pan Y, Huang J, Huang F, Chi W, Zhang K, Lin Z, Wu Y, He W, Wu J, Xie X, Huang J, Wei Q, Li T, Wu Z, Yu B, Gu J Tags: Scand J Rheumatol Source Type: journals

Effect of etanercept on serum levels of soluble cell adhesion molecules (sICAM-1, sVCAM-1, and sE-selectin) and vascular endothelial growth factor in patients with rheumatoid arthritis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Our study shows that, besides a rapid suppression of disease activity, serum sCAM and VEGF concentrations are downregulated following anti-tumour necrosis factor alpha (TNFalpha) therapy combined with MTX. Prolonged treatment with etanercept sustained or even more remarkably diminished the sCAM and VEGF serum concentrations. PMID: 19922018 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)
Source: Scandinavian Journal of Rheumatology - November 21, 2009 Category: Rheumatology Authors: Klimiuk P, Sierakowski S, Domyslawska I, Chwiecko J Tags: Scand J Rheumatol Source Type: journals

Hand bone loss measured by digital X-ray radiogrammetry is a predictor of joint damage in early rheumatoid arthritis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Loss of bone measured by DXR was found to be an independent predictor of radiological joint damage and may thus be an additional tool in the process of treatment decision in early RA. PMID: 19922017 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)
Source: Scandinavian Journal of Rheumatology - November 21, 2009 Category: Rheumatology Authors: Forslind K, Boonen A, Albertsson K, Hafström I, Svensson B, For The Barfot study Group Tags: Scand J Rheumatol Source Type: journals

Role of Manual Aspiration in Treating Pneumothorax after Computed Tomography-Guided Lung Biopsy.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Percutaneous manual aspiration of biopsy-induced pneumothorax performed immediately after biopsy may prevent worsening of pneumothorax and avoid chest tube placement. The amount of aspirated air can be predictive of the requirement for chest tube placement. PMID: 19922309 [PubMed - as supplied by publisher] (Source: Acta Radiologica)
Source: Acta Radiologica - November 21, 2009 Category: Radiology Authors: Yamagami T, Terayama K, Yoshimatsu R, Matsumoto T, Miura H, Nishimura T Tags: Acta Radiol Source Type: journals

Multidetector-Row Computed Tomographic Angiography Findings of Musculoskeletal Tumors: Retrospective Analysis and Correlation with Surgical Findings.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: CTA is a more accurate imaging technique than MRI in evaluating vascular invasion of musculoskeletal tumors, and provides valuable preoperative data. PMID: 19922313 [PubMed - as supplied by publisher] (Source: Acta Radiologica)
Source: Acta Radiologica - November 21, 2009 Category: Radiology Authors: Argin M, Isayev H, Kececi B, Arkun R, Sabah D Tags: Acta Radiol Source Type: journals

Age- and Sex-Associated Changes in Cerebral Glucose Metabolism in Normal Healthy Subjects: Statistical Parametric Mapping Analysis of F-18 Fluorodeoxyglucose Brain Positron Emission Tomography.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Using SPM, we found not only similar areas of brain, but also sex-specific cerebral areas of age-associated changes of FDG uptake. PMID: 19922315 [PubMed - as supplied by publisher] (Source: Acta Radiologica)
Source: Acta Radiologica - November 21, 2009 Category: Radiology Authors: Kim IJ, Kim SJ, Kim YK Tags: Acta Radiol Source Type: journals

Use of Automatic Tube Current Modulation With a Standardized Noise Index in Young Children Undergoing Chest Computed Tomography Scans With 64-Slice Multidetector Computed Tomography.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The z-axis ATCM method produces consistent image quality for young children undergoing 64-slice MDCT chest scans. With noise levels of NI=8 and 9 at 5-mm image slice thickness, one may obtain clinically acceptable images with significantly reduced radiation dose. PMID: 19922316 [PubMed - as supplied by publisher] (Source: Acta Radiologica)
Source: Acta Radiologica - November 21, 2009 Category: Radiology Authors: Peng Y, Li J, Ma D, Zhang Q, Liu Y, Zeng J, Sun G Tags: Acta Radiol Source Type: journals

Synchronous Parenchymal Renal Tumors of Different Histology in the Same Kidney.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: It is possible to suspect preoperatively the presence of tumors of different histologic subtypes within the same kidney. Imaging findings may provide information regarding the presence of lesions with different aggressiveness within the kidney, which may be helpful in therapeutic planning. PMID: 19922319 [PubMed - as supplied by publisher] (Source: Acta Radiologica)
Source: Acta Radiologica - November 21, 2009 Category: Radiology Authors: Capaccio E, Varca V, Simonato A, Toncini C, Carmignani G, Derchi LE Tags: Acta Radiol Source Type: journals

Inflammatory Response in Patients Undergoing Uterine Artery Embolization as Compared to Patients Undergoing Conventional Hysterectomy.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Uterine artery embolization generates a reduced inflammatory response compared with conventional hysterectomy. PMID: 19922320 [PubMed - as supplied by publisher] (Source: Acta Radiologica)
Source: Acta Radiologica - November 21, 2009 Category: Radiology Authors: Brøchner AC, Mygil B, Elle B, Toft P Tags: Acta Radiol Source Type: journals

Transport and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde in Caco-2 cells.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The transport and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde (BCA) was characterized in Caco-2 cells. BCA disappeared rapidly from the donor side without being transported to the receiver side during its absorptive transport across Caco-2 cells. Its metabolites 2'-hydroxycinnamaldehyde (HCA) and o-coumaric acid (OCA) were formed in both the donor and the receiver sides. HCA, in a separate study, also disappeared rapidly from the donor side, mostly being converted to its oxidative metabolite OCA during its absorptive transport across Caco-2 cells. OCA was transported rapidly in the absorptiv...
Source: Xenobiotica - November 21, 2009 Category: Research Authors: Lee K, Park SK, Kwon BM, Kim K, Yu HE, Ryu J, Oh SJ, Lee KS, Kang JS, Lee CW, Kwon MG, Kim HM Tags: Xenobiotica Source Type: journals

Influence of the MDR1 haplotype and CYP3A5 genotypes on cyclosporine blood level in Chinese renal transplant recipients.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The purpose of the study was to elucidate the influence of multidrug resistance gene (MDR1) haplotype and CYP3A5 genotype on cyclosporine (CsA) blood level in Chinese renal transplant recipients. CsA trough level (C(0)) and peak level (C(2)) of 115 patients 1 week and 1 month after renal transplantation were determined. MDR1 C1236T, G2677T/A, C3435T and CYP3A5*3 genotypes were determined by polymerase chain reaction (PCR) assays based on amplification refractory mutation. Dose-adjusted C(0) (C(0)/D), C(2) (C(2)/D) were 50.5 +/- 22.5, 267.8 +/- 110.1 ng.kg.(ml.mg)(-1) after 1 week of therapy, and 79.3 +/- 29.4, 406.0 +/...
Source: Xenobiotica - November 21, 2009 Category: Research Authors: Chen B, Zhang W, Fang J, Jin Z, Li J, Yu Z, Cai W Tags: Xenobiotica Source Type: journals

Cross-species comparisons of the pharmacokinetics of ibudilast.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To enable clinical development of ibudilast for new indications, its pharmacokinetics were characterized in mice, rats, rabbits, dogs, cynomolgus monkeys, and minipigs. Animal pharmacokinetics were compared with a separate study in healthy volunteers. Following oral dosing, the dose-normalized area under the curve (AUC) (DN-AUC(24h)) in humans is 896 ((ng*h ml(-1))/(mg kg(-1))), and in animals ranges from 0.3 to 87. The variability among species cannot be explained by intrinsic clearance, which in intravenous dosing experiments shows only moderate interspecies variation (13-41 l h(-1) m(-2)). A portal vein rat pharmaco...
Source: Xenobiotica - November 21, 2009 Category: Research Authors: Sanftner LM, Gibbons JA, Gross MI, Suzuki BM, Gaeta FC, Johnson KW Tags: Xenobiotica Source Type: journals

Dignity not fully upheld when seeking health care: Experiences expressed by individuals suffering from Ehlers-Danlos syndrome.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. The memory of not being respected is substantial for individuals with EDS and can last for years. As a result, lack of trust for the health-care system is created and they may experience difficulties in future encounters with health care. Therefore, health-care professionals should base their actions on norms that protect human dignity and confirm each patient as a unique human being with resources and abilities to master their own life. PMID: 19925271 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - November 21, 2009 Category: Rehabilitation Authors: Berglund B, Anne-Cathrine M, Randers I Tags: Disabil Rehabil Source Type: journals

Long-term effects of home rehabilitation after hip fracture - 1-year follow-up of functioning, balance confidence, and health-related quality of life in elderly people.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. The positive long-term effects were more pronounced among the participants in the HR group than among those who received CC, possibly due to the early start of the HR programme in hospital and its focus on self-efficacy and training of daily activities. However, one year after discharge a mojority of participants in both groups did not consider themselves to be fully recovered when they compared to their situation before the fracture. PMID: 19925273 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - November 21, 2009 Category: Rehabilitation Authors: Zidén L, Kreuter M, Frändin K Tags: Disabil Rehabil Source Type: journals

Exercise programs for children with cystic fibrosis: A systematic review of randomized controlled trials.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. There is some evidence to support that both aerobic and strength training can impact positively on pulmonary function, aerobic fitness, and strength. More RCTs in this area would be welcomed. There is potential for future research into designing exercise programs for children with CF using a combination of modalities. PMID: 19925275 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - November 21, 2009 Category: Rehabilitation Authors: van Doorn N Tags: Disabil Rehabil Source Type: journals

Construct validity of the late life function and disability instrument for adults with chronic conditions.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. Cross-sectional convergent validity of the LLFDI was supported when applied to adults 45-65 years of age with chronic conditions. PMID: 19925276 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - November 21, 2009 Category: Rehabilitation Authors: Hand C, Richardson J, Letts L, Stratford P Tags: Disabil Rehabil Source Type: journals

Leisure activities following a lower limb amputation.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. A decrease in leisure activity participation and the presence of constraints do not automatically translate into low levels of leisure satisfaction. PMID: 19925277 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - November 21, 2009 Category: Rehabilitation Authors: Couture M, Caron CD, Desrosiers J Tags: Disabil Rehabil Source Type: journals

Patient-driven loop control for ambulation function restoration in a non-invasive functional electrical stimulation system.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. According to the experiment results, this patient-driven loop control can be beneficial for patient with hemiplegia to restore their ambulation functions such as dorsi-flexion and plantar-flexion. The control strategy of this study has the potential to be employed not only in the FES system but also in other assistive devices. PMID: 19925278 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - November 21, 2009 Category: Rehabilitation Authors: Chen WL, Chen SC, Chen CC, Chou CH, Shih YY, Chen YL, Kuo TS Tags: Disabil Rehabil Source Type: journals

Researcher perspectives on competencies of return-to-work coordinators.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. RTW coordinators are essential contributors in RTW facilitation programs. This study identified specific competencies required to achieve success. More emphasis on mentorship and observation will be required to develop and evaluate necessary skills in this area. PMID: 19925279 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)
Source: Disability and Rehabilitation - November 21, 2009 Category: Rehabilitation Authors: Gardner BT, Pransky G, Shaw WS, Nha Hong Q, Loisel P Tags: Disabil Rehabil Source Type: journals