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Total 14448 results found since Jan 2013.

Protocol for a single-blind randomized clinical trial to test the efficacy of bilateral transcranial magnetic stimulation on upper extremity motor function in patients recovering from stroke
This study is currently in progress.Graphical Abstract
Source: Trials - September 22, 2023 Category: Research Source Type: clinical trials

A cardiovascular polypill for secondary stroke prevention in a tertiary centre in Ghana (SMAART): a phase 2 randomised clinical trial
Lancet Glob Health. 2023 Oct;11(10):e1619-e1628. doi: 10.1016/S2214-109X(23)00347-9.ABSTRACTBACKGROUND: A cardiovascular polypill containing generic drugs might facilitate sustained implementation of and adherence to evidence-based treatments, especially in resource-limited settings. However, the impact of a cardiovascular polypill in mitigating atherosclerotic risk among stroke survivors has not been assessed. We aimed to compare a polypill regimen with usual care on carotid intima-media thickness (CIMT) regression after ischaemic stroke.METHODS: In SMAART, a phase 2 parallel, open-label, assessor-masked, randomised clini...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Fred Stephen Sarfo Jenifer Voeks Sheila Adamu Benedict Apaw Agyei Manolo Agbenorku Nyantakyi Adu-Darko Mercy Adomah Oteng Vida Obese Rexford Adu Gyamfi Nathaniel Adusei Mensah Raelle Tagge Michael Ampofo Samuel Amoabeng Kontoh Samuel Blay Nguah Bruce Ovbi Source Type: research

NIH researchers develop new method to identify potential stroke therapies
First-of-its-kind study points to uric acid as a promising treatment for further investigation.
Source: National Institutes of Health (NIH) News Releases - September 20, 2023 Category: American Health Source Type: news

Researchers develop new method to identify potential stroke therapies
First-of-its-kind study points to uric acid as a promising treatment for further investigation.
Source: National Institutes of Health (NIH) News Releases - September 20, 2023 Category: American Health Source Type: news

International responses addressing the under-representation of older people in clinical research
This article provides an overview and critique of the current approaches to the inclusion of older people in clinical research and highlights policy gaps and limitations of current strategies.PMID:37724905 | DOI:10.1111/ajag.13234
Source: Australasian Journal on Ageing - September 19, 2023 Category: Geriatrics Authors: Susan C Markham Justin McNab Kate O'Loughlin Lindy Clemson Source Type: research

The Anesthesiology Physician-Scientist Pipeline: Current Status and Recommendations for Future Growth-An Initiative of the Anesthesia Research Council
Anesth Analg. 2023 Oct 1;137(4):728-742. doi: 10.1213/ANE.0000000000006520. Epub 2023 Sep 5.ABSTRACTThe limited number and diversity of resident physicians pursuing careers as physician-scientists in medicine has been a concern for many decades. The Anesthesia Research Council aimed to address the status of the anesthesiology physician-scientist pipeline, benchmarked against other medical specialties, and to develop strategic recommendations to sustain and expand the number and diversity of anesthesiology physician-scientists. The working group analyzed data from the Association of American Medical Colleges and the Nationa...
Source: Anesthesia and Analgesia - September 15, 2023 Category: Anesthesiology Authors: Charles W Emala Vivianne L Tawfik Meghan B Lane-Fall Paloma Toledo Cynthia A Wong Monica S Vavilala Lee A Fleisher Margaret Wood Source Type: research

Selecting stroke patients for thrombectomy: is CTA+ASPECTS enough?
Since 2014, a series of randomised controlled trails (RCTs) have demonstrated the benefit of endovascular thrombectomy (EVT) on functional outcome for the participants who had acute ischaemic stroke (AIS) with occlusion of a proximal intracranial artery in the anterior circulation. The characteristics of the people enrolled in these RCTs have been used to define recommended criteria to select patients for thrombectomy in clinical practice. The initial group of RCTs largely enrolled participants early after AIS (mostly under 6 hours) who had National Institutes of Health stroke scale scores ≥6 (range 0–42 with lowe...
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 14, 2023 Category: Neurosurgery Authors: Powers, W. Tags: Editorial commentaries Source Type: research

The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients
This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). A retrospective study was conducted on 657 CP/CPPS patients who visited The Third Xiangya Hospital of Central South University (Changsha, China) from November 2018 to November 2022. Patients were divided into two groups based on the timeline before and after the COVID-19 outbreak in China. The severity of CP/CPPS, penile erection status, anxiety, and depression was evaluated using the National Institutes of Health-Chronic Pro...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Wei-Jie Song Ji-Wei Huang Yuan Liu Wei Ding Zhi Long Le-Ye He Source Type: research