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Challenges of neural interfaces for stroke motor rehabilitation
More than 85% of stroke survivors suffer from different degrees of disability for the rest of their lives. They will require support that can vary from occasional to full time assistance. These conditions are also associated to an enormous economic impact for their families and health care systems. Current rehabilitation treatments have limited efficacy and their long-term effect is controversial. Here we review different challenges related to the design and development of neural interfaces for rehabilitative purposes. We analyze current bibliographic evidence of the effect of neuro-feedback in functional motor rehabilitat...
Source: Frontiers in Human Neuroscience - September 18, 2023 Category: Neuroscience Source Type: research

Soluble C-type lectin-like receptor 2 in stroke (CLECSTRO) study: protocol of a multicentre, prospective cohort of a novel platelet activation marker in acute ischaemic stroke and transient ischaemic attack
This study was approved by the Ethical Committee of the University of Yamanashi as the central ethical committee in agreement with the ethical committees of all collaborative stroke centres. Informed consent will be obtained by an opt-out form from the patients at each stroke centre according to the Ethical Guidelines for Medical and Biological Research Involving Human Subjects by the Japanese Ministry of Health, Labour and Welfare. Trial registration numbers NCT05579405, UMIN000048954
Source: BMJ Open - September 18, 2023 Category: General Medicine Authors: Uchiyama, S., Suzuki-Inoue, K., Wada, H., Okada, Y., Hirano, T., Nagao, T., Kinouchi, H., Itabashi, R., Hoshino, H., Oki, K., Honma, Y., Ito, N., Sugimori, H., Kawamura, M. Tags: Open access, Diagnostics Source Type: research

Automated Large Vessel Occlusion Detection Software and Thrombectomy Treatment Times
This study attempts to determine whether automated computed tomography angiogram interpretation coupled with secure group messaging can improve in-hospital endovascular stroke therapy workflows.
Source: JAMA Neurology - September 18, 2023 Category: Neurology Source Type: research

Outcomes in Patients With Poststroke Seizures
This systematic review and meta-analysis investigates the association of mortality, poor functional outcomes, recurrent stroke, and dementia in patients with poststroke seizures compared with patients without poststroke seizures.
Source: JAMA Neurology - September 18, 2023 Category: Neurology Source Type: research

Pulse rate variability predicted cardiovascular disease in sleep disordered breathing: The Guangdong sleep health study
Pulse rate variability (PRV) predicts stroke in patients with sleep disordered breathing (SDB). However, the relationship between PRV and cardiovascular disease (CVD) was unknown in SDB.
Source: Respiratory Medicine - September 18, 2023 Category: Respiratory Medicine Authors: Miaochan Lao, Qiong Ou, Guangliang Shan, Murui Zheng, Guo Pei, Yanxia Xu, Longlong Wang, Jiaoying Tan, Bin Lu Tags: Original Research Source Type: research

IJERPH, Vol. 20, Pages 6780: Developing and Planning a Protocol for Implementing Health Promoting Animal Assisted Interventions (AAI) in a Tertiary Health Setting
Simon Koblar The Ottawa Charter identifies that multiple levels of government, non-government, community, and other organizations should work together to facilitate health promotion, including in acute settings such as hospitals. We outline a method and protocol to achieve this, namely an Action Research (AR) framework for an Animal Assisted Intervention (AAI) in a tertiary health setting. Dogs Offering Support after Stroke (DOgSS) is an AR study at a major tertiary referral hospital. AAI has been reported to improve mood and quality of life for patients in hospitals. Our project objectives included applying for fun...
Source: International Journal of Environmental Research and Public Health - September 18, 2023 Category: Environmental Health Authors: M. Anne Hamilton-Bruce Janette Young Carmel Nottle Susan J. Hazel Austin G. Milton Sonya McDowall Ben Mani Simon Koblar Tags: Article Source Type: research

Another Step Forward in Our Ability to Predict Percutaneous Coronary Intervention Outcomes
Despite advancements in devices, technique, and patient selection, adverse events including bleeding, vascular complications, myocardial infarction, stroke, and death still occur during percutaneous coronary intervention (PCI). Accurate and up-to-date risk-adjusted models that predict mortality after PCI are important to inform clinical decision making, identify patient factors that increase risk, provide a standardized format to measure programmatic quality, and drive continuous quality improvement efforts to improve operator outcomes.
Source: The American Journal of Cardiology - September 18, 2023 Category: Cardiology Authors: Araba Ofosu-Somuah, Matthew A. Cavender, George A. Stouffer Tags: Editorial Source Type: research

Want to Remember Names? This Simple Trick From a Brain Training Expert Is a Stroke of Genius
Start with a weird image and then add motion.
Source: Reuters: Health - September 17, 2023 Category: Consumer Health News Source Type: news

TSPO exacerbates acute cerebral ischemia/reperfusion injury by inducing autophagy dysfunction
Exp Neurol. 2023 Sep 15:114542. doi: 10.1016/j.expneurol.2023.114542. Online ahead of print.ABSTRACTAutophagy is considered a double-edged sword, with a role in the regulation of the pathophysiological processes of the central nervous system (CNS) after cerebral ischemia-reperfusion injury (CIRI). The 18-kDa translocator protein (TSPO) is a highly conserved protein, with its expression level in the nervous system closely associated with the regulation of pathophysiological processes. In addition, the ligand of TSPO reduces neuroinflammation in brain diseases, but the potential role of TSPO in CIRI is largely undiscovered. ...
Source: Experimental Neurology - September 17, 2023 Category: Neurology Authors: Yusufu Mahemuti Kaheerman Kadeer Riqing Su Abudureheman Abula Yirizhati Aili Aierpati Maimaiti Subinuer Abulaiti Maimaitiyasheng Maimaitituerxun Tong Miao Shihao Jiang Aximujiang Axier Maimaitili Aisha Yongxin Wang Xiaojiang Cheng Source Type: research

Correction to Red flags for a concomitant giant cell arteritis in patients with vertebrobasilar stroke: a cross ‑sectional study and systematic review
Source: Acta Neurologica Belgica - September 17, 2023 Category: Neurology Source Type: research

Cerebellar stroke-like lesions combined with symmetrical multiple intracranial calcifications in MELAS
Source: Acta Neurologica Belgica - September 17, 2023 Category: Neurology Source Type: research

Treatment of patients with multiple organ dysfunction syndrome (MODS) with an electromagnetic field coupled to biorhythmically defined impulse configuration: the MicrocircMODS study
ConclusionPVT treatment was feasible and safe and could be performed without obstruction of standard patient care. An increase in microcirculatory blood flow, a rapid reduction in vasopressor use, and an improvement in global haemodynamics paralleled PVT treatment. Findings of this pilot study allowed forming a concept for a randomized trial for further proof.Graphical abstract
Source: Clinical Research in Cardiology - September 17, 2023 Category: Cardiology Source Type: research

Sensors, Vol. 23, Pages 7946: Explainable Risk Prediction of Post-Stroke Adverse Mental Outcomes Using Machine Learning Techniques in a Population of 1780 Patients
In this study, we aimed to develop a machine learning (ML) model to predict the risk of PSAMO. We retrospectively studied 1780 patients with stroke who were divided into PSAMO vs. no PSAMO groups based on results of validated depression and anxiety questionnaires. The features collected included demographic and sociological data, quality of life scores, stroke-related information, medical and medication history, and comorbidities. Recursive feature elimination was used to select features to input in parallel to eight ML algorithms to train and test the model. Bayesian optimization was used for hyperparameter tuning. Shaple...
Source: Sensors - September 17, 2023 Category: Biotechnology Authors: Chien Wei Oei Eddie Yin Kwee Ng Matthew Hok Shan Ng Ru-San Tan Yam Meng Chan Lai Gwen Chan Udyavara Rajendra Acharya Tags: Communication Source Type: research