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An alternative approach to autopsy education and training: changing of the guard.
PMID: 25319969 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Wilson ML Tags: Am J Clin Pathol Source Type: research

Point-of-Care Testing: Is Faster Better?
PMID: 25319970 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Rainey PM, Ulibarri M Tags: Am J Clin Pathol Source Type: research

Valuing value: the changing role of pathologists.
PMID: 25319971 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Misialek MJ Tags: Am J Clin Pathol Source Type: research

The eAutopsy: An Effective Virtual Tool for Exposing Medical Students to the Postmortem Examination.
CONCLUSIONS: The two forms of autopsy exposure performed similarly on a Likert-type survey assessing certain attitudes related to the procedure. However, the emotional impact of the live experience may be longer lasting. PMID: 25319973 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Talmon GA, Czarnecki D, Bernal K Tags: Am J Clin Pathol Source Type: research

Blastomycosis of bone: a clinicopathologic study.
CONCLUSION: Blastomycosis osteomyelitis should be considered in the differential diagnosis of bone tumor, particularly when there is history of residence or travel in endemic areas. This disease can be correctly identified at frozen section, thus offering rapid diagnosis. There is an excellent correlation between morphologic and microbiologic studies. PMID: 25319975 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Jain R, Singh K, Lamzabi I, Harbhajanka A, Gattuso P, Reddy VB Tags: Am J Clin Pathol Source Type: research

Establishing an evidence base for critical laboratory value thresholds.
CONCLUSIONS: Only a subset of laboratory critical value thresholds was optimally chosen for increased risk of in-hospital mortality, with a time urgency for most but not all critical values. For many tests, a prior hospital admission imparted a decreased risk of in-hospital death. PMID: 25319976 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Doering TA, Plapp F, Crawford JM Tags: Am J Clin Pathol Source Type: research

Canadian Association of Pathologists-Association canadienne des pathologistes National Standards Committee for High Complexity Testing/Immunohistochemistry: Guidelines for the Preparation, Release, and Storage of Unstained Archived Diagnostic Tissue Sections for Immunohistochemistry.
CONCLUSIONS: Clear communication between requesting and releasing laboratories will facilitate the proper preparation of unstained sections and also ensure that applicable privacy considerations are addressed. PMID: 25319977 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Cheung CC, Banerjee D, Barnes PJ, Berendt RC, Butany J, Canil S, Clarke BA, El-Zimaity H, Garratt J, Geldenhuys L, Gilks CB, Manning L, Mengel M, Perez-Ordonez B, Pilavdzic D, Riddell R, Swanson PE, Torlakovic EE Tags: Am J Clin Pathol Source Type: research

Low Frequency of HNPCC-Associated Microsatellite Instability and Aberrant MMR Protein Expression in Early-Onset Bladder Cancer.
CONCLUSIONS: In young patients with bladder tumors, MSI and defects in MMR protein expression were not more frequent than in a series of consecutive bladder tumors. Most bladder tumors in young patients are not to be attributed to Lynch syndrome. PMID: 25319978 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Giedl J, Schneckenpointner R, Filbeck T, Ruemmele P, Hofstaedter F, Burger M, Hartmann A, Stoehr R Tags: Am J Clin Pathol Source Type: research

Implementation of Point-of-Care Testing in an Ambulatory Practice of an Academic Medical Center.
CONCLUSIONS: POCT can significantly improve clinical operations with cost reductions through improved practice efficiency. PMID: 25319979 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Crocker JB, Lee-Lewandrowski E, Lewandrowski N, Baron J, Gregory K, Lewandrowski K Tags: Am J Clin Pathol Source Type: research

Reference range determination for whole-blood platelet aggregation using the multiplate analyzer.
CONCLUSIONS: These data demonstrate the importance of establishing locally relevant reference ranges. PMID: 25319980 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Peerschke EI, Castellone DD, Stroobants AK, Francis J Tags: Am J Clin Pathol Source Type: research

Derivation of Pediatric Within-Individual Biological Variation by Indirect Sampling Method: An LMS Approach.
CONCLUSIONS: The median CVi derived from patients with only two repeat biochemistry measurements may be considered reasonable estimates of CVi among children seeking treatment at primary care settings. The LMS approach allowed visualization of the continuous trends of CVi with age and extended the pediatric CVi estimation to younger than 4 years. PMID: 25319981 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Loh TP, Ranieri E, Metz MP Tags: Am J Clin Pathol Source Type: research

Improved Survival in p16-Positive Vaginal Cancers Across All Tumor Stages but No Correlation With MIB-1.
CONCLUSIONS: The p16 marker has a significant prognostic impact in primary squamous cell vaginal cancers across all tumor stages. PMID: 25319982 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Feldbaum VM, Flowers LC, Oprea-Ilies GM Tags: Am J Clin Pathol Source Type: research

Medullary-like hepatocellular carcinoma: an unusual histologic variant.
CONCLUSIONS: This report is presented to increase awareness of this unusual lesion and because it raises questions regarding the previous claim suggesting a less aggressive clinical course. PMID: 25319983 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Quist E, Talmon G, Hartman C, Wisecarver J Tags: Am J Clin Pathol Source Type: research

Myoid gonadal stromal tumor: a clinicopathologic study of three cases of a distinctive testicular tumor.
CONCLUSIONS: Myoid gonadal stromal tumors are small (<4 cm) indolent testicular tumors distinctly different from other sex cord-stromal tumors and are adequately managed by orchiectomy. PMID: 25319984 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Kao CS, Ulbright TM Tags: Am J Clin Pathol Source Type: research

Primary intrathymic lymphangioma.
CONCLUSIONS: Intrathymic lymphangioma should always be taken into consideration in the differential diagnosis of cystic mediastinal lesions in children and adult patients. PMID: 25319985 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Licci S, Puma F, Sbaraglia M, Ascani S Tags: Am J Clin Pathol Source Type: research

Pseudoinsulinoma in a white man with autoimmune hypoglycemia due to anti-insulin antibodies: value of the free C-Peptide assay.
CONCLUSIONS: In patients presenting with hypoglycemia with excessively high insulin levels, consideration needs to be given to autoimmune hypoglycemia due to anti-insulin antibodies as a cause. Additionally, if total C-peptide levels are increased, free C-peptide needs to be quantitated following polyethylene glycol precipitation. PMID: 25319986 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Arzamendi AE, Rajamani U, Jialal I Tags: Am J Clin Pathol Source Type: research

Benign Atypical Intravascular CD30+ T-Cell Proliferation: A Recently Described Reactive Lymphoproliferative Process and Simulator of Intravascular Lymphoma: Report of a Case Associated With Lichen Sclerosus and Review of the Literature.
CONCLUSIONS: This benign cutaneous lymphoproliferation needs to be distinguished from intravascular T-cell lymphoma, particularly from the intravascular variant of anaplastic large cell lymphoma. Obstruction of lymphatics due to lichen sclerosus with disrupted immune cell trafficking may result in the accumulation of activated CD30+ lymphocytes. PMID: 25319987 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Kempf W, Keller K, John H, Dommann-Scherrer C Tags: Am J Clin Pathol Source Type: research

AJCP Journal CME/SAM.
Authors: PMID: 25319988 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Tags: Am J Clin Pathol Source Type: research

Media Review.
PMID: 25319989 [PubMed - as supplied by publisher] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - October 21, 2014 Category: Pathology Authors: Hoda SA Tags: Am J Clin Pathol Source Type: research

When the rubber meets the road: dealing with a returning traveler from west Africa during the ebola outbreak of 2014.
PMID: 25239405 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Guarner J Tags: Am J Clin Pathol Source Type: research

Resident training in new technologies.
PMID: 25239406 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Wilson ML Tags: Am J Clin Pathol Source Type: research

IgG4+ Plasma Cells in Isolated Reactive Lymphadenopathy.
PMID: 25239407 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Cotta CV, Hsi ED Tags: Am J Clin Pathol Source Type: research

Cancer in low- and middle-income countries: where to start? Is it pathology?
PMID: 25239408 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Guarner J, Fleming K Tags: Am J Clin Pathol Source Type: research

Clinical Laboratory Immunology: An Indispensable Player in Laboratory Medicine.
CONCLUSIONS: It is anticipated that sharing this knowledge will increase awareness of the discipline of clinical laboratory immunology at the postdoctoral level with implications for the practice of laboratory medicine. PMID: 25239409 [PubMed - as supplied by publisher] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Tebo AE, Detrick B, Hamilton RG, Khanolkar A, O'Gorman MR, Schmitz JL, Abraham RS Tags: Am J Clin Pathol Source Type: research

The current state of resident training in genomic pathology: a comprehensive analysis using the resident in-service examination.
CONCLUSIONS: The RISE is a powerful tool for assessing the state of resident training in genomic pathology and current results suggest a significant deficit. The results also provide a baseline to assess future initiatives to improve genomics education for pathology residents such as those developed by the TRIG Working Group. PMID: 25239410 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Haspel RL, Rinder HM, Frank KM, Wagner J, Ali AM, Fisher PB, Parks ER, Training Residents in Genomics (TRIG) Working Group Tags: Am J Clin Pathol Source Type: research

CD8+ Lymphocyte Intratumoral Infiltration as a Stage-Independent Predictor of Merkel Cell Carcinoma Survival: A Population-Based Study.
CONCLUSIONS: This study of prospectively captured MCC cases supports the concept that cellular immunity is important in MCC outcome and that CD8+ lymphocyte infiltration adds prognostic information to conventional staging. PMID: 25239411 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Paulson KG, Iyer JG, Simonson WT, Blom A, Thibodeau RM, Schmidt M, Pietromonaco S, Sokil M, Warton EM, Asgari MM, Nghiem P Tags: Am J Clin Pathol Source Type: research

Abundance of IgG4+ Plasma Cells in Isolated Reactive Lymphadenopathy Is No Indication of IgG4-Related Disease.
CONCLUSION: Without a clinical suspicion of IgG4-related disease, these morphologic patterns and high numbers of IgG4-positive plasma cells should be interpreted with care to avoid an erroneous diagnosis of IgG4-related disease. PMID: 25239412 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Martinez LL, Friedländer E, van der Laak JA, Hebeda KM Tags: Am J Clin Pathol Source Type: research

Utility of measurement of interleukin-1ß and interleukin-8 in the diagnosis of complicated parapneumonic pleural effusions.
CONCLUSIONS: Measurement of IL-1β and IL-8 in pleural fluid may be useful in the early diagnosis of CPPE, although individually, it may not improve the results obtained with the PFLD. Further studies are needed to more firmly establish what role these new parameters can play in the diagnosis of CPPE. PMID: 25239413 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: San José ME, Ferreiro L, Soneira ME, González-Barcala FJ, Vázquez MC, Golpe A, Valdés L Tags: Am J Clin Pathol Source Type: research

Comparison study of the eosin-5'-maleimide binding test, flow cytometric osmotic fragility test, and cryohemolysis test in the diagnosis of hereditary spherocytosis.
CONCLUSIONS: Our results demonstrate that both the EMA binding and FC OF tests are useful as screening tests for the diagnosis of HS, but the cryohemolysis test has limited use due to its false positivity in IDA, with the Hb/MCHC ratio the most useful parameter for assessing the clinical severity of HS. PMID: 25239414 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Park SH, Park CJ, Lee BR, Cho YU, Jang S, Kim N, Koh KN, Im HJ, Seo JJ, Park ES, Lee JW, Yoo KH, Jung HL Tags: Am J Clin Pathol Source Type: research

Nevus-associated melanomas: clinicopathologic features.
CONCLUSIONS: Nevus-associated melanomas, which represent one-third of the melanomas in southeast Brazil, are associated with intermittent sun exposure, superficial spreading melanomas, and lower Breslow thickness. This is one of the largest series describing nevus-associated melanomas in Latin America. PMID: 25239415 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Shitara D, Nascimento MM, Puig S, Yamada S, Enokihara MM, Michalany N, Bagatin E Tags: Am J Clin Pathol Source Type: research

Thromboelastography is a suboptimal test for determination of the underlying cause of bleeding associated with cardiopulmonary bypass and may not predict a hypercoagulable state.
CONCLUSIONS: TEG had limited utility in identifying the underlying cause of bleeding and was not predictive of postoperative bleeding associated with cardiac surgery compared with conventional coagulation tests. A shortened TEG R time may not represent a hypercoagulable state. PMID: 25239416 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Welsh KJ, Padilla A, Dasgupta A, Nguyen AN, Wahed A Tags: Am J Clin Pathol Source Type: research

A cross-sectional pilot study of blood utilization in 27 hospitals in northern california.
CONCLUSIONS: There is awareness of the need for transfusion oversight. However, the findings show a wide spectrum of transfusion practice, and high-yield measures, such as electronic cross-match and transfusion triggers, have not been uniformly implemented. The results indicate that there is a role for blood centers to assist client hospitals to maximize their efficiency and reduce blood utilization. PMID: 25239417 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Bloch EM, Cohn C, Bruhn R, Hirschler N, Nguyen KA Tags: Am J Clin Pathol Source Type: research

Using the Hemoglobin Content of Reticulocytes (RET-He) to Evaluate Anemia in Patients With Cancer.
CONCLUSIONS: These results support the use of RET-He in the evaluation of iron deficiency in a cancer care setting. PMID: 25239418 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Peerschke EI, Pessin MS, Maslak P Tags: Am J Clin Pathol Source Type: research

Nocardiosis in 132 patients with cancer: microbiological and clinical analyses.
CONCLUSIONS: Diverse Nocardia species can cause secondary infections in patients with cancer. Timely species identification and antimicrobial susceptibility tests may guide treatment. PMID: 25239419 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Wang HL, Seo YH, LaSala PR, Tarrand JJ, Han XY Tags: Am J Clin Pathol Source Type: research

Analysis of the Leprosy Agents Mycobacterium leprae and Mycobacterium lepromatosis in Four Countries.
CONCLUSIONS: The leprosy agents vary in geographic distribution. Finding M lepromatosis in Brazil and Myanmar suggests wide existence of this newly discovered species. The leprosy manifestations likely vary with the etiologic agents. PMID: 25239420 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Han XY, Aung FM, Choon SE, Werner B Tags: Am J Clin Pathol Source Type: research

Diagnosis of cancer in rural rwanda: early outcomes of a phased approach to implement anatomic pathology services in resource-limited settings.
CONCLUSIONS: Our experience demonstrates that anatomic pathology services can be established in resource-limited settings and local capacity can be built to support accurate diagnoses. Our approach included leveraging partnerships, volunteer experts, and task shifting and will be expanded to include telepathology. PMID: 25239422 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Mpunga T, Tapela N, Hedt-Gauthier BL, Milner D, Nshimiyimana I, Muvugabigwi G, Moore M, Shulman DS, Pepoon JR, Shulman LN Tags: Am J Clin Pathol Source Type: research

Diagnostic Immunophenotype of Acute Promyelocytic Leukemia Before and Early During Therapy With All-trans Retinoic Acid.
CONCLUSIONS: Information about recent ATRA administration is critical for adequate interpretation of the flow cytometric findings in patients with suspected APL. PMID: 25239423 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Horna P, Zhang L, Sotomayor EM, Lancet JE, Moscinski LC Tags: Am J Clin Pathol Source Type: research

Do the Flags Related to Immature Granulocytes Reported by the Sysmex XE-5000 Warrant a Microscopic Slide Review?
CONCLUSIONS: The "Imm Gran?" flag has a poor analytical quality and gives no substantial information on the presence of blasts in the sample. We therefore suggest reporting the automated IG count without initial microscopic slide review. PMID: 25239424 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Eilertsen H, Hagve TA Tags: Am J Clin Pathol Source Type: research

Comparison of the aptima and cervista tests for detection of high-risk human papillomavirus in cervical cytology specimens.
CONCLUSIONS: We found poor positive percent agreement between the results of the Aptima and Cervista HPV tests and described an important source of false-positive Cervista results. PMID: 25239425 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Nolte FS, Ribeiro-Nesbitt DG Tags: Am J Clin Pathol Source Type: research

δβ-Thalassemia Trait: How Can We Discriminate It From β-Thalassemia Trait and Iron Deficiency Anemia?
CONCLUSIONS: RDW is the best parameter to discriminate δβ-TT from β-TT. The degree of anisocytosis in patients with β-TT and δβ-TT is strongly correlated with HbF. PMID: 25239426 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Authors: Velasco-Rodríguez D, Alonso-Domínguez JM, González-Fernández FA, Villarrubia J, Ropero P, Martínez-Nieto J, de la Fuente F, Guillén R, Acedo N, Serí C, Cava F Tags: Am J Clin Pathol Source Type: research

AJCP Journal CME/SAM.
Authors: PMID: 25239427 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - September 26, 2014 Category: Pathology Tags: Am J Clin Pathol Source Type: research

Learning to be a consultant: what should be taught.
PMID: 25125615 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Wilson ML Tags: Am J Clin Pathol Source Type: research

An analysis of clinical consultation activities in clinical pathology: who requests help and why.
CONCLUSIONS: At our laboratory, consultation requests primarily originate from primary care physicians. Consultation requests vary by caller type. PMID: 25125616 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Schmidt RL, Panlener J, Hussong JW Tags: Am J Clin Pathol Source Type: research

Loss of blast heterogeneity in myelodysplastic syndrome and other chronic myeloid neoplasms.
CONCLUSIONS: Analysis of a limited antibody panel with a focus on CD13/HLA-DR expression provides relatively high specificity and sensitivity for the detection of myeloid neoplasms. PMID: 25125617 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Jevremovic D, Timm MM, Reichard KK, Morice WG, Hanson CA, Viswanatha DS, Howard MT, Nguyen PL Tags: Am J Clin Pathol Source Type: research

Rapid detection of the active cardiac glycoside convallatoxin of lily of the valley using Loci digoxin assay.
CONCLUSIONS: LOCI digoxin assay can be used for rapid detection of convallatoxin, and Digibind can bind convallatoxin in vitro. PMID: 25125619 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Welsh KJ, Huang RS, Actor JK, Dasgupta A Tags: Am J Clin Pathol Source Type: research

Mesothelin expression in pancreatic mucinous cysts.
CONCLUSION: Our findings suggest that MLSN can be used as a marker of neoplastic transformation of epithelial cells in pancreatic mucinous cysts. The findings can help identify neoplastic mucinous epithelium. PMID: 25125620 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Frank R, Li S, Ahmad NA, Sepulveda AR, Jhala NC Tags: Am J Clin Pathol Source Type: research

Evaluation of Napsin A, TTF-1, p63, p40, and CK5/6 Immunohistochemical Stains in Pulmonary Neuroendocrine Tumors.
CONCLUSION: Pulmonary neuroendocrine tumors have a distinct but nonspecific profile on IHC panel commonly applied to subclassify NSCLCs. They are napsin A-/p40-/p63-/CK5/6-/TTF-1±. Recognizing this profile may have value in separating neuroendocrine tumors from NSCLCs. PMID: 25125621 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Zhang C, Schmidt LA, Hatanaka K, Thomas D, Lagstein A, Myers JL Tags: Am J Clin Pathol Source Type: research

A dual-fixed neutrophil substrate improves interpretation of antineutrophil cytoplasmic antibodies by indirect immunofluorescence.
CONCLUSIONS: Concomitant staining on formalin fixation of IIF-positive ethanol-fixed ANCA samples improves the interpretation of ANCA testing and is predictive of vasculitis autoantigens MPO and PR3. PMID: 25125622 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Lin MW, Silvestrini RA, Culican S, Campbell D, Fulcher DA Tags: Am J Clin Pathol Source Type: research

Platelet mapping assay interference due to platelet activation in heparinized samples.
CONCLUSIONS: Unanticipated platelet activation/aggregation occurring in the heparinized TEGPM samples lead to erroneous percent inhibition results. PMID: 25125623 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Nelles NJ, Chandler WL Tags: Am J Clin Pathol Source Type: research

Aggressive B-Cell Lymphomas With Translocations Involving BCL6 and MYC Have Distinct Clinical-Pathologic Characteristics.
CONCLUSIONS: B-cell lymphomas with translocations involving MYC and BCL6 have morphologic and immunophenotypic features suggestive of Burkitt lymphoma or gray zone lymphoma, and they tend to be diagnosed mainly in women, often in extranodal locations. PMID: 25125624 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - August 19, 2014 Category: Pathology Authors: Turakhia SK, Hill BT, Dufresne SD, Nakashima MO, Cotta CV Tags: Am J Clin Pathol Source Type: research