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Clinical utility of lactate dehydrogenase: a historical perspective.
PMID: 25596240 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Jialal I, Sokoll LJ Tags: Am J Clin Pathol Source Type: research

Detection of Human Papillomavirus 16, 18, and 45 in Women With ASC-US Cytology and the Risk of Cervical Precancer: Results From the CLEAR HPV Study.
CONCLUSIONS: We demonstrated that AHPV-GT is a reliable and effective test for cervical cancer risk stratification in women with an ASC-US cytology diagnosis. PMID: 25596241 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Castle PE, Cuzick J, Stoler MH, Wright TC, Reid JL, Dockter J, Giachetti C, Getman D Tags: Am J Clin Pathol Source Type: research

Automatic recognition of atypical lymphoid cells from peripheral blood by digital image analysis.
CONCLUSIONS: The method reaches a high precision in the recognition of five different types of lymphoid cells and could allow for the design of a diagnosis support tool in the future. PMID: 25596242 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Alférez S, Merino A, Bigorra L, Mujica L, Ruiz M, Rodellar J Tags: Am J Clin Pathol Source Type: research

The Vascular Marker CD31 Also Highlights Histiocytes and Histiocyte-Like Cells Within Cutaneous Tumors.
CONCLUSIONS: Our results indicate that CD31 can mark lesional cells and imitate vascular tumors in cutaneous histiocytomas and histiocytoma mimics, an error that can be avoided by using a panel of antibodies. PMID: 25596243 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Vanchinathan V, Mizramani N, Kantipudi R, Schwartz EJ, Sundram UN Tags: Am J Clin Pathol Source Type: research

Detection of acetylcholine receptor modulating antibodies by flow cytometry.
CONCLUSIONS: The new flow cytometric method using the RD cell platform provided higher quality clinical results, a more robust and efficient assay format, a significant cost savings, and less environmental burden. PMID: 25596244 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Lozier BK, Haven TR, Astill ME, Hill HR Tags: Am J Clin Pathol Source Type: research

Adequacy of core needle biopsy specimens and fine-needle aspirates for molecular testing of lung adenocarcinomas.
CONCLUSIONS: When paraffin-embedded tissue is used for molecular testing of lung cancer, CNB specimens are more likely than FNA specimens to provide adequate tissue for molecular testing. Obtaining a sufficient FNA specimen depends on the tumor size and the individual performing the biopsy. PMID: 25596245 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Schneider F, Smith MA, Lane MC, Pantanowitz L, Dacic S, Ohori NP Tags: Am J Clin Pathol Source Type: research

Bone marrow necrosis: ten-year retrospective review of bone marrow biopsy specimens.
CONCLUSIONS: The causes of bone marrow necrosis are diverse but should always prompt careful assessment for malignancy and infectious etiology. PMID: 25596246 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Wool GD, Deucher A Tags: Am J Clin Pathol Source Type: research

Flow cytometric analysis of lymphoid enhancer-binding factor 1 in diagnosis of chronic lymphocytic leukemia/small lymphocytic lymphoma.
CONCLUSIONS: Flow cytometric analysis of LEF1 is sufficient to differentiate CLL/SLL from other small B-cell lymphomas and may serve as a useful tool in the diagnosis of CLL/SLL. PMID: 25596247 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Amador-Ortiz C, Goolsby CL, Peterson LC, Wolniak KL, McLaughlin JL, Gao J, Chen YH Tags: Am J Clin Pathol Source Type: research

Thyroid carcinoma showing thymus-like elements: a clinicopathologic, immunohistochemical, ultrastructural, and molecular analysis.
CONCLUSIONS: GLUT-1 can be used as a novel biomarker for CASTLE, and combined detection of GLUT-1 with CD5 and CD117 aids in the diagnosis of this tumor. Aberrant expression of Bcl-2, p53, p16, E-cadherin, EGFR, C-KIT, and HER-2 may play important roles in the development of CASTLE. PMID: 25596248 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Wang YF, Liu B, Fan XS, Rao Q, Xu Y, Xia QY, Yu B, Shi SS, Zhou XJ Tags: Am J Clin Pathol Source Type: research

A hybrid approach to urine drug testing using high-resolution mass spectrometry and select immunoassays.
CONCLUSIONS: The hybrid approach to urine drug testing provides a simplified and analytically specific testing process that minimizes the need for secondary confirmation. PMID: 25596249 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: McMillin GA, Marin SJ, Johnson-Davis KL, Lawlor BG, Strathmann FG Tags: Am J Clin Pathol Source Type: research

Laboratory measurements of the oral direct factor xa inhibitor edoxaban: comparison of prothrombin time, activated partial thromboplastin time, and thrombin generation assay.
CONCLUSIONS: PT had disadvantages of a large variability among different PT reagents. aPTT could be used as a conventional and convenient test with a smaller variation among reagents. Thrombin generation was the most sensitive assay. PMID: 25596250 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Morishima Y, Kamisato C Tags: Am J Clin Pathol Source Type: research

Enhanced FHL2 and TGF-β1 Expression Is Associated With Invasive Growth and Poor Survival in Malignant Melanomas.
CONCLUSIONS: Enhanced FHL2 and TGF-β1 expression is correlated with poor survival in human malignant melanoma. Protumorigenic effects of autocrine TGF-β1 secretion might be exerted by induction of FHL2 expression in melanoma cells. Since melanomas treated with targeted therapies often do not show sufficient response rates, inhibition of FHL2 and/or TGF-β1 might be a promising therapeutic approach. PMID: 25596251 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Westphal P, Mauch C, Florin A, Czerwitzki J, Olligschläger N, Wodtke C, Schüle R, Büttner R, Friedrichs N Tags: Am J Clin Pathol Source Type: research

Pathologic Diagnostics of HER2 Positivity in Gastroesophageal Adenocarcinoma.
CONCLUSIONS: The currently used standardized HER2 scoring system is an excellent, clinically applicable method to establish HER2 status in appropriately educated and trained pathologists. PMID: 25596252 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Koopman T, Louwen M, Hage M, Smits MM, Imholz AL Tags: Am J Clin Pathol Source Type: research

Subcutaneous panniculitis-like T-cell lymphoma with bone marrow involvement.
CONCLUSIONS: SPTCL may rarely involve the bone marrow. Bone marrow infiltrates show a similar morphologic and immunophenotypic appearance to those in the subcutaneous fibroadipose tissue, including rimming of adipocytes by neoplastic lymphocytes. PMID: 25596253 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Brown NA, Ross CW, Gudjonsson JE, Wale D, Pawarode A, Maillard I, Hristov AC Tags: Am J Clin Pathol Source Type: research

Multifocal mantle cell lymphoma in situ in the setting of a composite lymphoma.
CONCLUSIONS: This unique case provides new insight into the pathogenesis of MCLIS. PMID: 25596254 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Sloan C, Xiong QB, Crivaro A, Steinman S, Bagg A Tags: Am J Clin Pathol Source Type: research

Solid pseudopapillary neoplasm collides with a well-differentiated pancreatic endocrine neoplasm in an adult man: case report and review of histogenesis.
CONCLUSIONS: A comparative analysis of immunoprofiles of these tumors yielded interesting findings, enabling us to postulate that SPNs may originate from a multipotential primordial cell that may follow different differentiation pathways, such as endocrine, epithelial, and acinar. The ultrastructures and immunophenotypic characteristics appear to support this hypothesis. PMID: 25596255 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Yan SX, Adair CF, Balani J, Mansour JC, Gokaslan ST Tags: Am J Clin Pathol Source Type: research

Cyclin D1-Positive Diffuse Large B-Cell Lymphoma With IGH-CCND1 Translocation and BCL6 Rearrangement: A Report of Two Cases.
CONCLUSIONS: Our study demonstrates convincingly that IGH-CCND1 rearrangement leading to cyclin D1 overexpression can occur in DLBCL and pose a potential diagnostic pitfall, requiring thorough knowledge of the clinicopathologic findings to allow accurate discrimination from a blastoid or pleomorphic MCL. The coexistence of IGH-CCND1 and IGH-BCL6 rearrangements suggest that BCL6 and cyclin D1 may cooperate in the pathogenesis of DLBCL. PMID: 25596256 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Al-Kawaaz M, Mathew S, Liu Y, Gomez ML, Chaviano F, Knowles DM, Orazi A, Tam W Tags: Am J Clin Pathol Source Type: research

A challenging diagnosis: crystal-storing histiocytosis in plasma cell myeloma.
CONCLUSIONS: The diagnosis was challenging; the bone marrow findings resembled features of other histiocytic disorders. The use of immunohistochemistry enabled the diagnosis of CSH in the presence of plasma cell myeloma. PMID: 25596257 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Lee JS, Im K, Park SN, Park HS, Kim JA, Choi Q, Kim SY, Cha CH, Oh HS, Kim IH, Lee DS Tags: Am J Clin Pathol Source Type: research

AJCP Journal CME/SAM.
Authors: PMID: 25596258 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Tags: Am J Clin Pathol Source Type: research

Bone marrow assessment in the diagnosis of acquired hemophagocytic lymphohistiocytosis in adults.
PMID: 25596259 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Machaczka M, Klimkowska M, Ho C, Yao X, Tian L, Li FY, Podoltsev N, Xu ML Tags: Am J Clin Pathol Source Type: research

Gallbladders: another source of radiation in the histology laboratory.
PMID: 25596260 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Renshaw AA, Gould EW, Tershakovec G Tags: Am J Clin Pathol Source Type: research

Pathology and malpractice.
PMID: 25596261 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - January 23, 2015 Category: Pathology Authors: Gatter K Tags: Am J Clin Pathol Source Type: research

Safety considerations in the laboratory testing of specimens suspected or known to contain ebola virus.
PMID: 25511134 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Iwen PC, Smith PW, Hewlett AL, Kratochvil CJ, Lisco SJ, Sullivan JN, Gibbs SG, Lowe JJ, Fey PD, Herrera VL, Sambol AR, Wisecarver JL, Hinrichs SH Tags: Am J Clin Pathol Source Type: research

Physician productivity: issues and controversies.
PMID: 25511135 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Storfa AH, Wilson ML Tags: Am J Clin Pathol Source Type: research

Starting at the beginning, ending at the end.
PMID: 25511136 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Wilson ML Tags: Am J Clin Pathol Source Type: research

Confidence, knowledge, and skills at the beginning of residency: a survey of pathology residents.
CONCLUSIONS: Respondents gained exposure to pathology primarily through elective rotations, and most felt the elective experience prepared them for pathology residency. However, elective time may be enhanced by providing opportunities for students to increase hands-on experience and understanding of resident duties. PMID: 25511137 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Hsieh CM, Nolan NJ Tags: Am J Clin Pathol Source Type: research

Cytogenetic and Flow Cytometry Evaluation of Richter Syndrome Reveals MYC, CDKN2A, IGH Alterations With Loss of CD52, CD62L and Increase of CD71 Antigen Expression as the Most Frequent Recurrent Abnormalities.
CONCLUSIONS: Newly diagnosed RS is an oncologic emergency, and a quick diagnostic decision is crucial in clinical practice. Therefore, in patients with CLL/SLL and rapidly enlarging asymmetric lymphadenopathy and/or extranodal tumors, we strongly advise FCM of fine-needle aspiration biopsy (FNAB) material, including CD62L, CD52, and CD71 analysis as well as assessment of karyotype and at least MYC abnormalities by FISH of the same FNAB material. Loss of CD52 expression in RS most likely predicts resistance to alemtuzumab therapy, which is frequently used in CLL. PMID: 25511139 [PubMed - in process] (Source: American Jo...
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Woroniecka R, Rymkiewicz G, Grygalewicz B, Błachnio K, Rygier J, Jarmuż-Szymczak M, Ratajczak B, Pieńkowska-Grela B Tags: Am J Clin Pathol Source Type: research

Lymphocytic cholecystitis/cholangitis.
CONCLUSIONS: The term lymphocytic cholecystitis/cholangitis is proposed. The potential clinical implications and pathogenesis of this inflammatory pattern and the differential diagnosis with other forms of acalculous cholecystitis are discussed. PMID: 25511140 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Jessurun J Tags: Am J Clin Pathol Source Type: research

Enhanced creatinine and estimated glomerular filtration rate reporting to facilitate detection of acute kidney injury.
CONCLUSION: While both creatinine reference limits and simple delta checks are insensitive for AKI identification, a simple algorithm can be implemented within a common laboratory information system to enhance AKI identification. PMID: 25511141 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Baron JM, Cheng XS, Bazari H, Bhan I, Lofgren C, Jaromin RT, Lewandrowski KB, Dighe AS Tags: Am J Clin Pathol Source Type: research

Most clinical laboratory testing in kampala occurs in high-volume, high-quality laboratories or low-volume, low-quality laboratories: a tale of two cities.
CONCLUSIONS: Clinical laboratory density in Kampala (1/1,781 persons) is high, approaching that in the United States (1/1,347 persons). Low-volume/low-quality and high-volume/high-quality laboratories do 90% of the daily aggregate testing. Quality improvement (QI) schemes for Africa must be appropriate to low-volume laboratories as well as to the large laboratories that have been the focus of previous QI efforts. PMID: 25511142 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Amukele TK, Schroeder LF, Jackson JB, Elbireer A Tags: Am J Clin Pathol Source Type: research

Blood Flow Cytometry in Sézary Syndrome: New Insights on Prognostic Relevance and Immunophenotypic Changes During Follow-up.
CONCLUSIONS: We confirm the relevance of CD26 negativity in SS diagnosis and monitoring. Nevertheless, the presence of rare CD26+ cases suggests that a multiparameter flow cytometry approach should be used. Changes in methylation profile could account for phenotypical heterogeneity. PMID: 25511143 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Novelli M, Fava P, Sarda C, Ponti R, Osella-Abate S, Savoia P, Bergallo M, Lisa F, Fierro MT, Quaglino P Tags: Am J Clin Pathol Source Type: research

Clinical presentation, progression, and outcome of patients with clonal B-cell counts of less than 5 × 109/l, 5 to 10 × 109/l, and more than 10 × 109/l and chronic lymphocytic leukemia immunophenotype.
CONCLUSIONS: Findings suggest that patients with B-cell counts of 5 to 10 × 10(9)/L behave clinically more similar to patients with B-cell counts of less than 5 × 10(9)/L. PMID: 25511144 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Foster AE, Nguyen TT, Al-Hammadi N, Frater JL, Hassan A, Kreisel F Tags: Am J Clin Pathol Source Type: research

A Limited Plasma Cell Flow Cytometry Panel With Reflex CD138 Immunohistochemistry Is an Optimal Workflow Process for Evaluating Plasma Cell Neoplasms in Bone Marrow Specimens.
CONCLUSIONS: Assessment of PC clonality using a limited FC panel followed by reflex CD138 immunohistochemistry on cases that are monoclonal by FC provides an optimal and cost-effective workflow for evaluating PCNs in BM samples. PMID: 25511145 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Chen ZW, Perkins SL, Weiss RL, Bahler DW, Hussong JW, Salama ME Tags: Am J Clin Pathol Source Type: research

Upfront Special Staining for Helicobacter pylori in Gastric Biopsy Specimens Is Not Indicated.
CONCLUSIONS: Upfront staining of gastric biopsy specimens is not cost-effective since a significant proportion of the gastric biopsy specimens were normal or showed minimal inflammation; in none of these biopsy specimens was the organism found. Special stains should be performed only in selected biopsy specimens that reveal any degree of chronic active gastritis or moderate inactive gastritis. PMID: 25511146 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Chitkara Y Tags: Am J Clin Pathol Source Type: research

Evaluation of Allele-Specific PCR and Immunohistochemistry for the Detection of BRAF V600E Mutations in Hairy Cell Leukemia.
CONCLUSIONS: VE1 immunohistochemistry is more sensitive than allele-specific PCR in FFPE bone marrow specimens and can be applied to decalcified core biopsy specimens that are not appropriate for molecular techniques. PMID: 25511147 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Brown NA, Betz BL, Weigelin HC, Elenitoba-Johnson KS, Lim MS, Bailey NG Tags: Am J Clin Pathol Source Type: research

Downtime procedures for the 21st century: using a fully integrated health record for uninterrupted electronic reporting of laboratory results during laboratory information system downtimes.
CONCLUSIONS: With the capabilities of EMRs and LISs rapidly evolving, information technology (IT) teams, laboratories, and clinicians need to collaborate closely, review their systems' capabilities, and design innovative ways to apply all available IT functions to optimize patient care during downtimes. PMID: 25511148 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Oral B, Cullen RM, Diaz DL, Hod EA, Kratz A Tags: Am J Clin Pathol Source Type: research

Blast phase in chronic myelogenous leukemia is skewed toward unusual blast types in patients treated with tyrosine kinase inhibitors: a comparative study of 67 cases.
CONCLUSIONS: Blast phase CML in TKI- and non-TKI-treated patients differs in the morphology and immunophenotype of blasts, cytogenetic findings, and associated findings in the peripheral blood and bone marrow. PMID: 25511149 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Shi Y, Rand AJ, Crow JH, Moore JO, Lagoo AS Tags: Am J Clin Pathol Source Type: research

The Utility of BRAF V600E Mutation-Specific Antibody VE1 for the Diagnosis of Hairy Cell Leukemia.
CONCLUSIONS: VE1 immunohistochemistry is a useful and convenient surrogate for detecting BRAF V600E mutation in BM biopsy specimens decalcified with hydrochloric or formic acid-based solutions. PMID: 25511150 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Uppal G, Ly V, Wang ZX, Bajaj R, Solomides CC, Banks PM, Medeiros LJ, Peiper SC, Gong JZ Tags: Am J Clin Pathol Source Type: research

Reliability of the Xpert HPV Assay to Detect High-Risk Human Papillomavirus DNA in a Colposcopy Referral Population.
CONCLUSIONS: The Xpert assay was sensitive and reliable for the detection of hrHPV and the identification of women with CIN2+. PMID: 25511151 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Castle PE, Smith KM, Davis TE, Schmeler KM, Ferris DG, Savage AH, Gray JE, Stoler MH, Wright TC, Ferenczy A, Einstein MH Tags: Am J Clin Pathol Source Type: research

Reference intervals data mining: no longer a probability paper method.
CONCLUSIONS: The presented statistical algorithm is shown to be an accurate and practical tool for reference interval calculations. PMID: 25511152 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Katayev A, Fleming JK, Luo D, Fisher AH, Sharp TM Tags: Am J Clin Pathol Source Type: research

Uncovering bias in the cytologic evaluation of cervical squamous lesions.
CONCLUSIONS: Cytotechnologists are not influenced by an expected number of abnormal Pap cases per day since this would result in deviation toward the mean daily rate of diagnosis. Possible explanations for the unanticipated clustering of SIL interpretations include clinical clustering effects or, alternatively, the influence a SIL interpretation might have on lowering the threshold for this interpretation again in subsequent specimens on the same day. The analysis presented here could serve as a model to detect bias in other aspects of medical decision making. PMID: 25511153 [PubMed - in process] (Source: American Jour...
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Authors: Larson AR, Cibas ES, Granter SR, Laga AC Tags: Am J Clin Pathol Source Type: research

AJCP Journal CME/SAM.
Authors: PMID: 25511154 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 20, 2014 Category: Pathology Tags: Am J Clin Pathol Source Type: research

The challenge of integrating informatics training during residency.
PMID: 25389323 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 16, 2014 Category: Pathology Authors: Riben M Tags: Am J Clin Pathol Source Type: research

Napsin a: another milestone in the subclassification of ovarian carcinoma.
PMID: 25389324 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 16, 2014 Category: Pathology Authors: Köbel M, Duggan MA Tags: Am J Clin Pathol Source Type: research

Primary care physicians and the laboratory: now and the future.
PMID: 25389325 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 16, 2014 Category: Pathology Authors: Marques MB, Hickner J, Thompson PJ, Taylor JR Tags: Am J Clin Pathol Source Type: research

The Next Chapter in Patient Blood Management: Real-Time Clinical Decision Support.
CONCLUSIONS: We have been able to significantly reduce inappropriate blood transfusions and related costs through an educational initiative coupled with real-time CDS. In deriving increased value out of health care, CDS can be applied to a number of overuse measures in laboratory testing, radiology, and therapy such as antibiotics, as outlined by the American Board of Internal Medicine's Choosing Wisely campaign. PMID: 25389326 [PubMed - as supplied by publisher] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 16, 2014 Category: Pathology Authors: Goodnough LT, Shah N Tags: Am J Clin Pathol Source Type: research

Longitudinal engagement of pathology residents: a proposed approach for informatics training.
CONCLUSIONS: In transforming the ways in which pathology residencies teach their trainees informatics, the prospects of realizing its potential utility are heightened. PMID: 25389327 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 16, 2014 Category: Pathology Authors: Rao LK, Gilbertson JR Tags: Am J Clin Pathol Source Type: research

HER2 Heterogeneity Affects Trastuzumab Responses and Survival in Patients With HER2-Positive Metastatic Breast Cancer.
CONCLUSIONS: These results suggest that accurate assessment of HER2 status, including HER2 heterogeneity, is important in predicting trastuzumab responses and outcomes in patients with HER2-positive metastatic breast cancer. PMID: 25389328 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 16, 2014 Category: Pathology Authors: Lee HJ, Seo AN, Kim EJ, Jang MH, Suh KJ, Ryu HS, Kim YJ, Kim JH, Im SA, Gong G, Jung KH, Park IA, Park SY Tags: Am J Clin Pathol Source Type: research

p16INK4a Immunohistochemistry in Cervical Biopsy Specimens: A Systematic Review and Meta-Analysis of the Interobserver Agreement.
CONCLUSIONS: The published literature indicates improved interobserver agreement of the diagnosis of CIN2+ with the conjunctive use of H&E morphology with p16(INK4a) immunohistochemistry compared with H&E morphology alone. PMID: 25389329 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 16, 2014 Category: Pathology Authors: Reuschenbach M, Wentzensen N, Dijkstra MG, von Knebel Doeberitz M, Arbyn M Tags: Am J Clin Pathol Source Type: research

Cancer tracking: clinician compliance and program outcome.
CONCLUSIONS: Confirmation that the physician caring for a patient receives a pathology diagnosis is important for patient management and quality assurance. While the surgical pathology report was placed in the chart, it was impossible to confirm that the responsible physician had reviewed the report in 9% of cases. Techniques for communication and confirmation of transmission of anatomic pathology diagnoses need to be developed. PMID: 25389330 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 16, 2014 Category: Pathology Authors: Layfield LJ, Schnabel JL Tags: Am J Clin Pathol Source Type: research