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Diagnostic microbiology: the accelerating transition from culture-based to molecular-based methods.
PMID: 25972317 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Wilson ML Tags: Am J Clin Pathol Source Type: research

Molecular Pathology of Hereditary and Sporadic Medullary Thyroid Carcinomas.
CONCLUSIONS: Molecular genetic testing is routinely performed to identify hereditary cases. In addition, understanding the molecular basis of both hereditary and sporadic MTC has led to the development of targeted therapy with tyrosine kinase inhibitors. Although additional data are needed, tumor mutation status may affect response to targeted therapy. Therefore, it is possible that genetic testing of tumor tissue to predict treatment response, as is currently done for other cancer types, may come into practice in the future. PMID: 25972318 [PubMed - as supplied by publisher] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Chernock RD, Hagemann IS Tags: Am J Clin Pathol Source Type: research

KRAS Mutations in Mucinous Lesions of the Uterus.
CONCLUSIONS: The results suggest a possible association between KRAS mutations and mucinous differentiation in endometrial carcinogenesis. KRAS status can help in assessing benign from precursor or malignant mucinous lesions as well as differentiate endometrial lesions from those of cervical origin. PMID: 25972319 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: He M, Jackson CL, Gubrod RB, Breese V, Steinhoff M, Lawrence WD, Xiong J Tags: Am J Clin Pathol Source Type: research

Flow cytometric identification of immunophenotypically aberrant T-cell clusters on skin shave biopsy specimens from patients with mycosis fungoides.
CONCLUSIONS: FC is capable of identifying putative neoplastic cells on SSB specimens from patients with MF. Bright homogeneous CD26 expression is a common and previously undescribed immunophenotypic aberrancy on MF skin infiltrates. PMID: 25972320 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Horna P, Kurant D, Sokol L, Sotomayor EM, Moscinski L, Glass LF Tags: Am J Clin Pathol Source Type: research

Lymphoplasmacytic lymphoma and marginal zone lymphoma in the bone marrow: paratrabecular involvement as an important distinguishing feature.
CONCLUSIONS: LPL can be reliably distinguished from MZL in the bone marrow by using a combination of pathology characteristics. Our findings stress the diagnostic importance of using the combination of the following parameters for a correct LPL diagnosis: paratrabecular infiltration, the presence of lymphoplasmacytoid cells and cells with Dutcher bodies, and an increased number of mast cells in addition to the presence of MYD88 mutation. PMID: 25972321 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Bassarova A, Trøen G, Spetalen S, Micci F, Tierens A, Delabie J Tags: Am J Clin Pathol Source Type: research

Consultative issues in surgical neuropathology: a retrospective review of the rationale for submitting cases for expert review.
CONCLUSIONS: Pathologists who predominately submit cases with a preliminary diagnosis rendered seek expert consultation while clinicians seek a second opinion. PMID: 25972322 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Lipp ES, Clark AC, McLendon RE Tags: Am J Clin Pathol Source Type: research

Osteopontin Regulates VEGFA and ICAM-1 mRNA Expression in Breast Carcinoma.
CONCLUSIONS: Our results support that osteopontin regulates ICAM-1 and VEGFA expression mainly in triple-negative/basal-like breast carcinomas, suggesting a relevant role in the pathogenesis and tumor progression of this molecular subtype. Moreover, VEGFA mRNA levels showed an independent prognostic value in patients with breast cancer. PMID: 25972323 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Ortiz-Martínez F, Sanmartín E, Pomares-Navarro E, Pérez-Balaguer A, Andrés L, Sánchez-Payá J, Aranda FI, Lerma E, Peiró G Tags: Am J Clin Pathol Source Type: research

Differential diagnostic value of "blue reticulated chondroid-like material" in aneurysmal bone cysts: a classic histopathologic analysis of 215 cases.
CONCLUSIONS: BRC appears to be a unique histopathologic feature of ABC, making it valuable to differentiate benign ABC from TOS. Simple H&E stain can be economically performed anywhere. PMID: 25972324 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Bahk WJ, Mirra JM Tags: Am J Clin Pathol Source Type: research

p16/CDKN2A FISH in Differentiation of Diffuse Malignant Peritoneal Mesothelioma From Mesothelial Hyperplasia and Epithelial Ovarian Cancer.
CONCLUSIONS: Our study suggests that p16 FISH analysis is useful in differentiating DMPM from RMH and EOC when homozygous deletion is detected. PMID: 25972325 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Ito T, Hamasaki M, Matsumoto S, Hiroshima K, Tsujimura T, Kawai T, Shimao Y, Marutsuka K, Moriguchi S, Maruyama R, Miyamoto S, Nabeshima K Tags: Am J Clin Pathol Source Type: research

Salivary gland tumor fine-needle aspiration cytology: a proposal for a risk stratification classification.
CONCLUSIONS: Salivary gland FNA categorization into commonly encountered morphologic categories provides risk stratification, which translates to a simplified classification scheme of benign, NUMP, suspicious, and positive for malignancy similar to the paradigm in other organ systems. PMID: 25972326 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Griffith CC, Pai RK, Schneider F, Duvvuri U, Ferris RL, Johnson JT, Seethala RR Tags: Am J Clin Pathol Source Type: research

A case series of clinically undiagnosed hematopoietic neoplasms discovered at autopsy.
CONCLUSIONS: These cases illustrate the importance of the traditional postmortem examination in not only confirming clinical diagnoses but also identifying previously unknown diagnoses. Hematologic malignancies may present with nonspecific clinical manifestations, and this series of cases also emphasizes the necessity for widening the differential diagnosis in patients with unexplained lactic acidosis and hepatic failure to include hematopoietic malignancies since prompt treatment may be lifesaving. PMID: 25972327 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Podduturi V, Guileyardo JM, Soto LR, Krause JR Tags: Am J Clin Pathol Source Type: research

Low-cost workflow improvement reduces gastrointestinal block use 17% by altering classic histotechnology testing.
CONCLUSIONS: This simple, low-cost, low-effort process change yielded immediate and significant time savings for grossing and histology staff, increased job satisfaction, and challenges conventional histotechnology teaching. PMID: 25972328 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Steussy B, Gailey M, Becker K, Fuller E, Jans M, Lewis S, Guerin L, Kirby P, Robinson R Tags: Am J Clin Pathol Source Type: research

FGFR2 Assessment in Gastric Cancer Using Quantitative Real-Time Polymerase Chain Reaction, Fluorescent In Situ Hybridization, and Immunohistochemistry.
CONCLUSIONS: FFPE biopsy tissues are an adequate source for FGFR2 evaluation in gastric carcinomas, and a qPCR-based copy number assay can be used for screening. IHC is also a valid and practical method for evaluating FGFR2, considering frequent heterogeneity. PMID: 25972329 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Park YS, Na YS, Ryu MH, Lee CW, Park HJ, Lee JK, Park SR, Ryoo BY, Kang YK Tags: Am J Clin Pathol Source Type: research

Conventional karyotyping and fluorescence in situ hybridization: an effective utilization strategy in diagnostic adult acute myeloid leukemia.
CONCLUSIONS: In adult AML, FISH rarely provides additional information when karyotyping is adequate. We therefore propose an evidence-based, cost-effective algorithmic approach for routine conventional karyotype and FISH testing in adult AML workup. PMID: 25972330 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: He R, Wiktor AE, Hanson CA, Ketterling RP, Kurtin PJ, Van Dyke DL, Litzow MR, Howard MH, Reichard KK Tags: Am J Clin Pathol Source Type: research

Endoscopic ultrasound fine-needle aspiration cytology mutation profiling using targeted next-generation sequencing: personalized care for rectal cancer.
CONCLUSIONS: Our data demonstrate the successful ability to apply a single multiplex test to allow multigene mutation detection from malignant LN cytology specimen DNA collected by EUS FNA. PMID: 25972331 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Gleeson FC, Kipp BR, Voss JS, Campion MB, Minot DM, Tu ZJ, Klee EW, Sciallis AP, Graham RP, Lazaridis KN, Henry MR, Levy MJ Tags: Am J Clin Pathol Source Type: research

Little things make big things happen: angiolymphatic invasion and tumor necrosis prognosticate the outcome of locally advanced non-small cell lung cancer treated with a prior induction therapy.
CONCLUSION: Our series is the first to report the prognostic impact of ALI and TN in induction-treated LA-NSCLC. The presence of ALI and TN should be included in the pathologic reports. PMID: 25972332 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Marquez-Medina D, Martin-Marco A, Caldero SG, Montero-Fernandez A Tags: Am J Clin Pathol Source Type: research

Characteristics and Antibiotic Use Associated With Short-Term Risk of Clostridium difficile Infection Among Hospitalized Patients.
CONCLUSIONS: In hospitalized patients, treatment with intravenous vancomycin within the prior 8 weeks of a first negative PCR test for C difficile is a risk factor for short-term risk for hospital-acquired CDI. Repeat testing guidelines for C difficile PCR should take into consideration patients who may be at high risk for short-term acquisition of CDI. PMID: 25972333 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Aldrete Sdel M, Magee MJ, Friedman-Moraco RJ, Chan AW, Banks GG, Burd EM, Kraft CS Tags: Am J Clin Pathol Source Type: research

Loss of BAP1 Expression in Basal Cell Carcinomas in Patients With Germline BAP1 Mutations.
CONCLUSIONS: Loss of BAP1 expression could be associated with the development of BCC in patients with germline BAP1 mutations. These results suggest that BCC may be a component of the expanding category of tumors associated with this syndrome. PMID: 25972334 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Mochel MC, Piris A, Nose V, Hoang MP Tags: Am J Clin Pathol Source Type: research

AJCP Journal CME/SAM.
Authors: PMID: 25972335 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Tags: Am J Clin Pathol Source Type: research

Tattoos containing useful messages.
PMID: 25972336 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Byard RW Tags: Am J Clin Pathol Source Type: research

What is hidden in tattoos?
PMID: 25972337 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Jonsson BH, Winzer R, Carson HJ Tags: Am J Clin Pathol Source Type: research

Test utilization is a quality control issue.
PMID: 25972338 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Authors: Plebani M Tags: Am J Clin Pathol Source Type: research

Correction.
Authors: PMID: 25972339 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 15, 2015 Category: Pathology Tags: Am J Clin Pathol Source Type: research

Academic laboratory medicine at 50 years and getting stronger.
PMID: 25873490 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Rinder HM Tags: Am J Clin Pathol Source Type: research

Decreasing inappropriate laboratory test utilization: controlling costs and improving quality of care.
PMID: 25873491 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Wilson ML Tags: Am J Clin Pathol Source Type: research

Searching for CALRity in Myeloproliferative Neoplasms.
PMID: 25873492 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Cook JR Tags: Am J Clin Pathol Source Type: research

Positive surgical margins in renal cell carcinoma: translating tumor biology into clinical outcomes.
PMID: 25873493 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Picken MM, Wang L, Gupta GN Tags: Am J Clin Pathol Source Type: research

Reducing duplicate testing: a comparison of two clinical decision support tools.
CONCLUSIONS: Structural and process changes that require laboratory contact and justification for duplicate testing are more effective than interventions that allow providers to bypass alerts without justification at point of computerized physician order entry. PMID: 25873494 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Procop GW, Keating C, Stagno P, Kottke-Marchant K, Partin M, Tuttle R, Wyllie R Tags: Am J Clin Pathol Source Type: research

Impact of a prospective review program for reference laboratory testing requests.
CONCLUSIONS: Formal prospective review of reference laboratory testing requests resulted in substantial cost containment and improved the efficiency of patient care. PMID: 25873495 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Greenblatt MB, Nowak JA, Quade CC, Tanasijevic M, Lindeman N, Jarolim P Tags: Am J Clin Pathol Source Type: research

CALR, JAK2, and MPL Mutation Profiles in Patients With Four Different Subtypes of Myeloproliferative Neoplasms: Primary Myelofibrosis, Essential Thrombocythemia, Polycythemia Vera, and Myeloproliferative Neoplasm, Unclassifiable.
CONCLUSIONS: The prognostic significance of CALR mutations likely differs among the MPN subtypes. PMID: 25873496 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Kim SY, Im K, Park SN, Kwon J, Kim JA, Lee DS Tags: Am J Clin Pathol Source Type: research

Partial nephrectomy for renal tumors: lack of correlation between margin status and local recurrence.
CONCLUSIONS: A literature review of 3,803 cases, including our study, shows positive margins in 173, of which 13 recurred; however, 39 with negative margins also recurred. A positive margin in PN seldom correlates with a local recurrence. However, protection from recurrence is not ensured by a negative margin. PMID: 25873497 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Antic T, Taxy JB Tags: Am J Clin Pathol Source Type: research

Evaluation of multiple real-time PCR tests on nasal samples in a large MRSA surveillance program.
CONCLUSIONS: Our results suggest that the performance of the three commercial assays is similar. When assessing economic cost benefit of methicillin-resistant Staphylococcus aureus screening, the two measures with the most impact are the cost of the test and the specificity of the assay results. PMID: 25873498 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Patel PA, Robicsek A, Grayes A, Schora DM, Peterson KE, Wright MO, Peterson LR Tags: Am J Clin Pathol Source Type: research

Significance of paneth cell metaplasia in barrett esophagus: a morphologic and clinicopathologic study.
CONCLUSIONS: The presence of PCM is associated with less disease regression and is not associated with more disease progression. PMID: 25873500 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Chen W, Frankel WL, Cronley KM, Yu L, Zhou X, Yearsley MM Tags: Am J Clin Pathol Source Type: research

Extensive Survey of STAT6 Expression in a Large Series of Mesenchymal Tumors.
CONCLUSIONS: Strong nuclear STAT6 is largely specific for SFTs. Physiologic low-level cytoplasmic/nuclear expression is common in mesenchymal neoplasia and is of uncertain significance. PMID: 25873501 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Demicco EG, Harms PW, Patel RM, Smith SC, Ingram D, Torres K, Carskadon SL, Camelo-Piragua S, McHugh JB, Siddiqui J, Palanisamy N, Lucas DR, Lazar AJ, Wang WL Tags: Am J Clin Pathol Source Type: research

Indirect estimation of pediatric between-individual biological variation data for 22 common serum biochemistries.
CONCLUSIONS: These data are comparable to those reported by the Canadian Laboratory Initiative on Pediatric Reference Intervals study and the Ricos database for adults. This study reports the CVg trends and data for boys and girls by year of age, which have not been described previously. PMID: 25873502 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Loh TP, Metz MP Tags: Am J Clin Pathol Source Type: research

Detection and genotype of high-risk human papillomavirus in fine-needle aspirates of patients with metastatic squamous cell carcinoma is helpful in determining tumor origin.
CONCLUSIONS: HR-HPV detection and genotyping can be performed on lymph node FNAs with metastatic squamous cell carcinoma using the Roche cobas 4800 system. The presence of HR-HPV and/or HPV 16 is a reliable indicator of the metastatic squamous cell carcinoma originating from the oropharynx. PMID: 25873503 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Baldassarri R, Aronberg R, Levi AW, Yarbrough WG, Kowalski D, Chhieng D Tags: Am J Clin Pathol Source Type: research

Malignant effusions correlate with poorer prognosis in patients with diffuse large B-cell lymphoma.
CONCLUSIONS: Patients who have DLBCL with lymphomatous effusions have a poor prognosis and should be treated as having stage IV disease. The analysis of effusions for tumor cells would be a useful addition to the routine workup. PMID: 25873505 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Chen YP, Huang HY, Lin KP, Medeiros LJ, Chen TY, Chang KC Tags: Am J Clin Pathol Source Type: research

B-ALL Minimal Residual Disease Flow Cytometry: An Application of a Novel Method for Optimization of a Single-Tube Model.
CONCLUSIONS: Constructing a flow cytometry panel using a rigorous, objective, quantitative method permits optimization and avoids problems of interdependence and redundancy in a large, multiantigen panel. PMID: 25873506 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Shaver AC, Greig BW, Mosse CA, Seegmiller AC Tags: Am J Clin Pathol Source Type: research

Increased Levels of Tumor Necrosis Factor-α Involved in Rituximab-Related Acute Pulmonary Fibrosis in Diffuse Large B-Cell Lymphoma.
CONCLUSIONS: We observe that increased TNF-α levels may be involved in rituximab-related acute pulmonary fibrosis. PMID: 25873507 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Zhang X, Guo X, Pan J Tags: Am J Clin Pathol Source Type: research

Primary rhabdomyosarcoma of the pineal gland.
CONCLUSIONS: Pineal RMS is a rare disease with poor prognosis. Optimal management is unknown but likely to involve aggressive multimodality therapy. PMID: 25873508 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Lau SK, Cykowski MD, Desai S, Cao Y, Fuller GN, Bruner J, Okazaki I Tags: Am J Clin Pathol Source Type: research

Myocardial changes in a patient with anorexia nervosa: a case report and review of literature.
CONCLUSIONS: The gross findings in the heart correlate with the previously described anomalies on cardiac ultrasound of patients with AN. The fibrosis and myxoid material deposition might be a direct consequence of starvation and the mechanism of death in some patients with AN. PMID: 25873509 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Lamzabi I, Syed S, Reddy VB, Jain R, Harbhajanka A, Arunkumar P Tags: Am J Clin Pathol Source Type: research

Myeloid and Lymphoid Neoplasm With Abnormalities of FGFR1 Presenting With Trilineage Blasts and RUNX1 Rearrangement: A Case Report and Review of Literature.
CONCLUSIONS: To our knowledge, this is the first reported case of a myeloid and lymphoid neoplasm with abnormalities of FGFR1 with t(17;21)(p13;q22) and trilineage blasts. PMID: 25873510 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Kumar KR, Chen W, Koduru PR, Luu HS Tags: Am J Clin Pathol Source Type: research

Clinicocytopathologic correlation in an atypical presentation of lymphadenopathy with review of literature.
CONCLUSIONS: The cytologic findings of CSD in an atypical abdominal presentation are similar to those of a classic presentation. Laboratory workup for atypical CSD should include at least two other modalities aside from cytomorphologic features. Close clinical and cytologic correlation avoided potentially unnecessary and harmful surgery and enabled timely treatment. PMID: 25873511 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Choi AH, Bolaris M, Nguyen DK, Panosyan EH, Lasky JL, Duane GB Tags: Am J Clin Pathol Source Type: research

Paradoxical bleeding and thrombosis in a patient with afibrinogenemia and fibrinogen mumbai mutation.
CONCLUSIONS: Presence of both bleeding and thrombotic manifestations in a patient with afibrinogenemia in the presence of other associated risk factors warrants a very careful individualized approach in the management of patients with afibrinogenemia. PMID: 25873512 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Authors: Mukaddam A, Patil R, Jadli A, Chandrakala S, Ghosh K, Shetty S Tags: Am J Clin Pathol Source Type: research

AJCP Journal CME/SAM.
Authors: PMID: 25873513 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Tags: Am J Clin Pathol Source Type: research

Correction.
Authors: PMID: 25873514 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - April 18, 2015 Category: Pathology Tags: Am J Clin Pathol Source Type: research

Evaluation of treponemal serum tests performed on cerebrospinal fluid for diagnosis of neurosyphilis.
CONCLUSIONS: Treponemal serum tests performed on CSF were useful in identifying two patients with nonreactive CSF-VDRL. PMID: 25779998 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2015 Category: Pathology Authors: Guarner J, Jost H, Pillay A, Sun Y, Cox D, Notenboom R, Workowski K Tags: Am J Clin Pathol Source Type: research

Follow-up Outcomes in a Large Cohort of Patients With HPV-Negative LSIL Cervical Screening Test Results.
CONCLUSIONS: This is the largest study documenting follow-up results for patients with HPV-negative LSIL results based on prevalent US FDA-approved cotesting methods from one collection vial. These data document that risk for follow-up HSILs in these patients is low and also that no cervical cancers were diagnosed. These findings support recent recommendations for repeat cotesting after 1 year as an appropriate option for patients with HPV-negative LSIL results. PMID: 25779999 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2015 Category: Pathology Authors: Barron S, Austin RM, Li Z, Zhao C Tags: Am J Clin Pathol Source Type: research

Relationship of pathologic factors to efficacy of sorafenib treatment in patients with metastatic clear cell renal cell carcinoma.
CONCLUSIONS: As a novel histologic prognostic parameter, growth pattern may be useful for predicting response to sorafenib treatment. PMID: 25780000 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2015 Category: Pathology Authors: Araki H, Tsuzuki T, Kimura T, Tanaka K, Yamada S, Sassa N, Yoshino Y, Hattori R, Gotoh M Tags: Am J Clin Pathol Source Type: research

Detection of BRAF Mutations on Direct Smears of Thyroid Fine-Needle Aspirates Through Cell Transfer Technique.
CONCLUSIONS: PCR-based BRAF mutational testing can be reliably performed on the direct smears of the thyroid FNA specimens through the application of CTT. PMID: 25780001 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2015 Category: Pathology Authors: Shi Q, Ibrahim A, Herbert K, Carvin M, Randolph M, Post KM, Curless K, Chen S, Cramer HM, Cheng L, Wu HH Tags: Am J Clin Pathol Source Type: research