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Behcet's Disease

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Outcomes in Neuro-Behçet'sOutcomes in Neuro-Behçet's
Neuro-Behcet's is a severe condition, and this characteristic makes it worse. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 19, 2014 Category: Consumer Health News Tags: Rheumatology Viewpoint Source Type: news

Apremilast Clears Behcet's Ulcers
SAN DIEGO (MedPage Today) -- An investigational small molecule known as apremilast was successful in clearing the oral ulcers characteristic of Behcet's syndrome, a researcher reported here. (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - October 28, 2013 Category: Dermatology Source Type: news

Apremilast Potential Treatment for Behcet'sApremilast Potential Treatment for Behcet's
Few options are available for this rare inflammatory disease, and the first-in-class oral targeted phosphodiesterase 4 inhibitor quickly relieves the painful oral and genital ulcers of Behcet's. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 28, 2013 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Approaches to Immunosuppression in Behcet's DiseaseApproaches to Immunosuppression in Behcet's Disease
Gain new insights into Becet's Disease immunopathology and a new area of targeted therapy. Immunotherapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 12, 2013 Category: Consumer Health News Tags: Allergy & Clinical Immunology Journal Article Source Type: news

What is the Criteria for Diagnosing Beçhet’s disease?
Discussion Beçhet’s disease (BD) is a multisystem vasculitis named for the Turkish dermatologist, Hulusi Beçhet. It has a prevalance in one study of 5.2-7.1 per 100,000 adults. It is more common in males than females but it depends on the cohort studied and there is variation among different ancestral groups. Venous vasculitis usually causes thrombotic events whereas arterial vasculitis causes aneurysms and thrombosis. Involvement of the central nervous system vasculature can be a major problem. Central venous thrombosis can cause isolated intracranial hypertension but also aphasia, hemiparesis and sei...
Source: PediatricEducation.org - August 12, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Aphthous Ulcers (Canker Sores)
The shallow ulceration surrounded by a ring of erythema is characteristic for aphthous ulcers (canker sores). This patient’s otherwise negative history rules out Behcet’s disease. (Source: Consultant Live)
Source: Consultant Live - June 28, 2013 Category: Primary Care Source Type: news

Celgene Apremilast Phase II trial demonstrates efficacy for Behcet's disease
Switzerland-based Celgene International's Phase II trial of oral small-molecule inhibitor of phosphodiesterase 4 (PDE4), Apremilast, has demonstrated statistical significance for primary and secondary endpoints in patients with Behcet's disease (BD). (Source: Drug Development Technology)
Source: Drug Development Technology - June 16, 2013 Category: Pharmaceuticals Source Type: news

Behcet's Syndrome
Title: Behcet's SyndromeCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 6/10/2013 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - June 10, 2013 Category: Rheumatology Source Type: news

Researchers Identify New Gene Variants Associated With Risk For Behcet's Disease
Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. For nearly 2,000 years, traders used this 4,000-mile network linking the Far East with Europe to exchange goods, culture and, in the case of the Silk Road disease, genes. National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the advance online issue of Nature Genetics... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 8, 2013 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

Genetic mystery of Behcet's disease unfolds along the ancient Silk Road
Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. For nearly 2,000 years, traders used this 4,000-mile network linking the Far East with Europe to exchange goods, culture and, in the case of the Silk Road disease, genes. National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the Jan. 6, 2013, advance online issue of Nature Genetics. (Source: NHGRI Press Releases)
Source: NHGRI Press Releases - January 7, 2013 Category: Genetics & Stem Cells Source Type: news

Behcet's Disease - Interesting Information Unfolds Along the Ancient Silk Road
Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. (Source: Disabled World)
Source: Disabled World - January 7, 2013 Category: Disability Tags: Health and Disability Source Type: news

Genetic mystery of Behcet's disease unfolds along the ancient Silk Road
Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. For nearly 2,000 years, traders used this 4,000-mile network linking the Far East with Europe to exchange goods, culture and, in the case of the Silk Road disease, genes. National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the Jan. 6, 2013, advance online issue of Nature Genetics. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - January 7, 2013 Category: American Health Source Type: news

Genetic mystery of Behcet's disease unfolds along the ancient Silk Road
Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 6, 2013 Category: Science Source Type: news

Genetic mystery of Behcet's disease unfolds along the ancient Silk Road
(NIH/National Human Genome Research Institute) Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the Jan. 6, 2013, advance online issue of Nature Genetics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 6, 2013 Category: Global & Universal Source Type: news

Adalimumab for the Treatment of Behcet's DiseaseAdalimumab for the Treatment of Behcet's Disease
How effective is adalimumab in treating patients with refractory/relapsing Behcet's disease? Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 25, 2012 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

XOMA Announces Servier Has Initiated Phase 3 Gevokizumab Trial in Patients With Behcet's Uveitis
The objective of this study is to evaluate the efficacy of gevokizumab as compared to placebo on top of current standard of care (immunosuppressive therapy and oral corticosteroids) in reducing the risk of Behcet's disease uveitis exacerbations and to assess the safety of gevokizumab. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - September 27, 2012 Category: Pharmaceuticals Source Type: news

XOMA Announces Manufacturing Agreement With Les Laboratoires Servier and Boehringer Ingelheim
BERKELEY, Calif., Aug. 3, 2012 (GLOBE NEWSWIRE) -- XOMA Corporation (Nasdaq:XOMA) announced today its partner Les Laboratoires Servier (Servier) and the Company have entered into an agreement with Boehringer Ingelheim to transfer XOMA's technology and process for the commercial manufacture of gevokizumab, XOMA's novel interleukin 1-beta (IL-1beta) allosteric modulating antibody. Gevokizumab currently is in Phase 3 clinical development in patients with non-infectious uveitis (NIU) involving the intermediate and/or posterior segment of the eye. The global development plan includes a Phase 3 trial to be conducted by Servier i...
Source: Medical News (via PRIMEZONE) - August 3, 2012 Category: Pharmaceuticals Source Type: news

Infliximab reduces uveoretinitis in Behcet disease
NEW YORK (Reuters Health) - Infliximab is safe and effective for treating uveoretinitis in Behcet disease, a new multi-center study shows. (Source: Modern Medicine)
Source: Modern Medicine - June 1, 2012 Category: Journals (General) Source Type: news

What Is Behçet's Disease?
Behçet's disease (Behcet's Disease) is an autoimmune disease that results from damage to blood vessels throughout the body, particularly veins. In an autoimmune disease, the immune system attacks and harms the body's own tissues. (Source: About.com Eating Disorders)
Source: About.com Eating Disorders - February 6, 2012 Category: Eating Disorders and Weight Management Authors: highbloodpressure.guide at about.com Tags: health Source Type: news

The downside of sex with Neanderthals
Some modern humans carry immune genes that originated in Neanderthals and a related species. But these genes may have come at a priceOne question seemed to hang in the air more than any other when scientists first turned the powerful techniques of modern genetics on the fragile and damaged remains of ancient humans: did we or didn't we? Have sex with them, that is.The answer came after years of painstaking work, when material extracted from the leg of a Neanderthal and the fingerbone of a Denisovan, an apparent sister species, yielded readable DNA. It turned out that most of us have some of their genes. The Neanderthals co...
Source: Guardian Unlimited Science - August 25, 2011 Category: Science Authors: Ian Sample Tags: Science Genetics Neanderthal man Evolution Immunology Health Society guardian.co.uk Blogposts Source Type: news

Lower Initial Doses of IFN Effective for Behcet's Uveitis
Starting with a low dose of interferon (IFN) for Behcet's uveitis and raising it as necessary works just as well as higher-dose protocols, with fewer side effects, Turkish researchers say. Reuters Health Information (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - March 22, 2011 Category: Opthalmology Tags: Ophthalmology News Source Type: news

Major Vessel Involvement in Behçet's Disease: An Update
This review explores the complications of and the best therapies for Behcet disease. Current Opinion in Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - December 30, 2010 Category: Rheumatology Tags: Rheumatology Journal Article Source Type: news

Behcet's Takes Higher Toll in Men (CME/CE)
(MedPage Today) -- Men with Behçet's disease are much more likely than women to die of this chronic multisystem vasculitis, a large French study found. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - September 8, 2010 Category: Rheumatology Source Type: news

Horizon scanning: XOMA 052 designated orphan drug by FDA and EMEA for treatment of behcet's disease
Source: GlobeNewswire Area: News The FDA and the EMEA have designated XOMA 052, an antibody to interleukin-1 beta, an orphan drug for the treatment of Behcet's disease. In June 2010, XOMA announced positive results from an open-label pilot study of XOMA 052 in Behcet's disease patients who were suffering from uveitis, despite maximal doses of immunosuppressive medicines. All seven patients who enrolled in the trial displayed rapid reduction of intraocular inflammation and improvement in visual acuity or other ophthalmic measures following a single treatment. XOMA has now completed a phase II clinical trial in uveitis of B...
Source: NeLM - News - August 4, 2010 Category: Drugs & Pharmacology Source Type: news

XOMA 052 Designated Orphan Drug by FDA for Treatment of Behcet's Disease
BERKELEY, Calif., Aug. 4, 2010 (GLOBE NEWSWIRE) -- XOMA Ltd. (Nasdaq:XOMA), a leader in the discovery and development of therapeutic antibodies, announced that the U.S. Food and Drug Administration has designated XOMA 052, an antibody to interleukin-1 beta, an orphan drug for the treatment of Behcet's disease. As previously announced, the Committee for Orphan Medical Products of the European Medicines Agency has recommended the granting of orphan medicinal product designation for XOMA 052 for the same indication in the European Union. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - August 4, 2010 Category: Pharmaceuticals Source Type: news

XOMA 052 Orphan Drug Designation for Behcet's Disease Recommended by European Medicines Agency
BERKELEY, Calif., July 29, 2010 (GLOBE NEWSWIRE) -- XOMA Ltd. (Nasdaq:XOMA), a leader in the discovery and development of therapeutic antibodies, announced that the Committee for Orphan Medical Products of the European Medicines Agency (EMA) has adopted a positive opinion and recommends the granting of orphan medicinal product designation for XOMA 052, an antibody to interleukin-1 beta, for the treatment of Behcet's disease. Positive opinions are submitted to the European Commission for decision and are generally adopted within 30 days of receipt. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - July 29, 2010 Category: Pharmaceuticals Source Type: news

Disease genes that followed the Silk Road identified
Researchers have found susceptibility to Behcet's disease, a painful, inflammatory condition, to be associated with genes involved in the body's immune response. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 25, 2010 Category: Science Source Type: news

Genetics Home Reference: Behcet disease
(Source: NLM General Announcements)
Source: NLM General Announcements - July 19, 2010 Category: Databases & Libraries Source Type: news

NIH Genetic Collaboration Brings New Meaning to the Silk Road
Source: National Institute of Arthritis and Musculoskeletal and Skin Diseases - Related MedlinePlus Page: Behcet's Syndrome (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 15, 2010 Category: Consumer Health News Source Type: news

Research On Behcet's Disease Brings New Meaning To The Silk Road
Researchers with the National Institutes of Health have found susceptibility to Behcet's diseaseBehcet's disease, a painful, inflammatory condition, to be associated with genes involved in the body's immune response. Although the Greek physician Hippocrates described Behcet's disease (pronounced BET'-chet's), more than 2,000 years ago, the condition existed in relative obscurity until the early 20th century... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 14, 2010 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

NIH Genetic Collaboration Brings New Meaning to the Silk Road
Researchers with the National Institutes of Health have found susceptibility to Behcet's disease, a painful, inflammatory condition, to be associated with genes involved in the body's immune response. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - July 12, 2010 Category: American Health Source Type: news

NIH genetic collaboration brings new meaning to the Silk Road
(NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases) Researchers with the National Institutes of Health have found susceptibility to Behcet's disease, a painful, inflammatory condition, to be associated with genes involved in the body's immune response. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 12, 2010 Category: Global & Universal Source Type: news

Interferon Alpha Achieves Remission of Uveitis in Behcet's Disease
Almost all patients with severe uveitis due to Behcet's disease responded to treatment with interferon alpha in a German study, the researchers report. Reuters Health Information (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - June 23, 2010 Category: Rheumatology Tags: Rheumatology News Source Type: news

Behcet's Disease Increases Mortality, Especially in Men
Patients with Behcet's disease (BD), particularly men, have higher than average long-term mortality rates, French researchers reported online May 23rd in Arthritis & Rheumatism. Reuters Health Information (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - June 17, 2010 Category: Rheumatology Tags: Rheumatology News Source Type: news

Positive Clinical Findings Presented on XOMA 052 in Debilitating Eye Disease
ROME, June 17, 2010 (GLOBE NEWSWIRE) -- XOMA Ltd. (Nasdaq:XOMA), a leader in the discovery and development of therapeutic antibodies, announced positive results from an open-label pilot study of XOMA 052 in patients with uveitis of Behcet's disease who were suffering from vision-threatening exacerbations despite maximal doses of immunosuppressive medicines. All seven patients who enrolled in the trial displayed rapid reduction of intraocular inflammation and improvement in visual acuity or other ophthalmic measures following a single treatment with XOMA 052, a therapeutic antibody candidate that inhibits the inflammatory c...
Source: Medical News (via PRIMEZONE) - June 17, 2010 Category: Pharmaceuticals Source Type: news

Abstract Published on Initial Results From XOMA 052 Clinical Trial in Behcet's Disease
BERKELEY, Calif., May 12, 2010 (GLOBE NEWSWIRE) -- XOMA Ltd. (Nasdaq:XOMA), a leader in the discovery and development of therapeutic antibodies, announced the publication of an abstract titled, "Safe, Rapid-onset and Sustained Biological Activity of IL-1 beta Regulating Antibody XOMA 052 in Resistant Uveitis of Behcet's Disease: Preliminary Results of a Pilot Trial." Uveitis of Behcet's disease is an auto-inflammatory condition that can result in blindness or partial vision loss as described below. The abstract will be presented June 17, 2010 during the annual European Congress of Rheumatology in Rome, Italy by Professor A...
Source: Medical News (via PRIMEZONE) - May 12, 2010 Category: Pharmaceuticals Source Type: news

Medical panel
Introductions to the members of the BSS Medical Panel (Source: Behcet's Syndrome Society: Medical)
Source: Behcet's Syndrome Society: Medical - November 30, 2008 Category: Rheumatology Source Type: news

Medical Advisory Panel
Introductions to the members of the BSS Medical Panel (Source: Behcet's Syndrome Society: Medical)
Source: Behcet's Syndrome Society: Medical - November 30, 2008 Category: Rheumatology Source Type: news

It's Not So Sweet
This case study of Behcet's disease offers a brief overview of this uncommon and serious condition. What does a nurse need to know? Journal of Pediatric Health Care (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - November 26, 2008 Category: Rheumatology Tags: Nursing Source Type: news

Behcet's disease
— Comprehensive overview covers symptoms and treatment of this inflammatory syndrome. Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - October 30, 2008 Category: Consumer Health News Source Type: news

MedlinePlus: Síndrome de Behcet
(Source: NLM General Announcements)
Source: NLM General Announcements - September 22, 2008 Category: Databases & Libraries Source Type: news

Elevated TAFI linked to Behcet disease
High levels of thrombin activatable fibrinolysis inhibitor may contribute to the increased risk for thrombosis found in patients with the chronic vasculitis condition Behçet disease, Spanish researchers say. (Source: MedWire News - Thrombosis)
Source: MedWire News - Thrombosis - May 16, 2008 Category: Internal Medicine Source Type: news

Update on Ocular Behcet's Disease
Behcet's disease is a multisystemic disorder of recurrent acute inflammation that manifests itself predominantly as uveitis. Expert Review of Ophthalmology (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - February 13, 2008 Category: Opthalmology Tags: Ophthalmology Source Type: news

International conferences
on Behçet’s disease take place every two years. (Source: Behcet's Syndrome Society: Medical)
Source: Behcet's Syndrome Society: Medical - January 29, 2008 Category: Rheumatology Source Type: news

Clinical papers
Recent papers on Behçet’s disease, with links to abstracts or free full text where available. (Source: Behcet's Syndrome Society: Medical)
Source: Behcet's Syndrome Society: Medical - January 29, 2008 Category: Rheumatology Source Type: news

Information for patients
Information about what Behçet's disease is, how it is diagnosed and treated, and what similar disorders exist, plus leaflets to download. (Source: Behcet's Syndrome Society: Medical)
Source: Behcet's Syndrome Society: Medical - January 29, 2008 Category: Rheumatology Source Type: news