Determinants of non-attendance at face-to-face and telemedicine ophthalmic consultations
Conclusion Persistent non-attendance among underserved populations attending telemedicine appointments highlights the challenge digital transformation faces for reducing healthcare inequalities. Implementation of new programmes should be accompanied by investigation into the differential health outcomes of vulnerable populations. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Wagner, S. K., Raja, L., Cortina-Borja, M., Huemer, J., Struyven, R., Keane, P. A., Balaskas, K., Sim, D. A., Thomas, P. B. M., Rahi, J. S., Solebo, A. L., Kang, S. Tags: Open access Epidemiology Source Type: research

Lacrimal gland activity in lacrimal drainage obstruction: exploring the potential cross-talk between the tear secretion and outflow
Conclusion Tear flow rate from palpebral lobes of patients with unilateral lacrimal outflow obstruction shows a significant reduction compared with the contralateral side. The potential ways of communications between the tear drainage and the tear production mechanisms need to be explored further. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Singh, S., Srivastav, S., Bothra, N., Paulsen, F., Ali, M. J. Tags: Oculoplastic and orbit Source Type: research

Lower eyelid lengthening in facial nerve palsy: when is a periosteal flap required?
Conclusions MCT plication and stabilisation appear to be closely linked to the need for lower eyelid lengthening procedures, particularly in patients who have also undergone LTS and/or those within the ‘contraction phase’ of FNP. Unnecessary loss of horizontal tarsal length (particularly during LTS procedures) must be avoided in patients with FNP. Surgeons managing such patients should take care to identify inadvertent eyelid shortening early and be prepared to perform a lateral periosteal flap when required. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Jamison, A., Patel, B. C., Hunt, S., Malhotra, R. Tags: Oculoplastic and orbit Source Type: research

Papillary vitreous detachment as a possible accomplice in non-arteritic anterior ischaemic optic neuropathy
Conclusion Peripapillary wrinkles and superficial vessel protrusion may be signs of papillary vitreous detachment-related traction in NAION. Papillary vitreous detachment may play an important role in NAION pathogenesis. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Li, D., Sun, S., Liang, J., Yue, Y., Yang, J., Zhi, Y., Zhang, X., Yu, R., Li, X. Tags: Open access Neuro-ophthalmology and strabismus Source Type: research

Association of retinal optical coherence tomography metrics and polygenic risk scores with cognitive function and future cognitive decline
Conclusions and relevance Retinal OCT measurements are significantly associated with genetic risk of neurodegenerative disease and may serve as biomarkers predictive of future cognitive impairment. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Sekimitsu, S., Shweikh, Y., Shareef, S., Zhao, Y., Elze, T., Segre, A., Wiggs, J., Zebardast, N. Tags: Neuro-ophthalmology and strabismus Source Type: research

Prevalence and associated factors of myopia in children and adolescents in Russia: the Ural Children Eye Study
Conclusions In this ethnically mixed urban school children population from Russia, prevalence of any myopia (65.6%) and high myopia (4.6%) in children aged 17+ years was higher than in adult populations in the same region and it was lower than in East Asian school children, with similar associated factors. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Bikbov, M. M., Kazakbaeva, G. M., Fakhretdinova, A. A., Tuliakova, A. M., Iakupova, E. M., Panda-Jonas, S., Gilemzianova, L. I., Garipova, L. A., Khakimov, D. A., Islamova, L. I., Jonas, J. B. Tags: Paediatric ophthalmology Source Type: research

Low-dose atropine 0.01% for the treatment of childhood myopia: a pan-India multicentric retrospective study
Conclusion Low-dose atropine (0.01%) effectively reduces myopia progression over 2 years in Indian children. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Saxena, R., Gupta, V., Dhiman, R., Joseph, E., Agarkar, S., Neena, R., Magdalene, D., Jethani, J., Ganesh, S. C., Patil, M., Gogri, P., Gadaginamath, S., Sen, P., Sukhija, J., Mishra, D., Matalia, J. H., Sahu, A., Kapoor, S., Nishanth, S., Chaurasia, S., Tags: Paediatric ophthalmology Source Type: research

Obesity paradox in uveal melanoma: high body mass index is associated with low metastatic risk
Conclusion Obesity and elevated serum leptin levels are associated with a lower risk for developing metastases and dying from uveal melanoma. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Sabazade, S., Opalko, A., Herrspiegel, C., Gill, V. T., Plastino, F., Andre, H., Stalhammar, G. Tags: Open access Ocular Oncology Source Type: research

Risk factors for cataract in retinoblastoma management
Conclusions Repeated IAC and/or IvitC with melphalan were the most common eye-preserving therapies that induced cataract formation. The toxic effect of melphalan was an essential factor in cataract development, as indicated by the association of cataract occurrence with the melphalan dose. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Jia, S., Wen, X., Yu, J., Zhou, M., Yang, L., Feng, Y., He, X., Jia, R., Fan, J., Fan, X. Tags: Open access Ocular oncology Source Type: research

Intraocular medulloepithelioma clinical features and management of 11 cases
Conclusions Initial misdiagnosis, delay in diagnosis and subsequent misdirected management is not uncommon in medulloepithelioma. The presence of multiple cysts in the tumour and retrolental neoplastic cyclitic membrane detected by UBM can offer certain information. Selective intra-arterial melphalan may prevent further tumour growth, but longer follow-up is necessary until treatment efficacy is fully evaluated. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Yi, X., Meng, F., Bi, Y., He, L., Qian, J., Xue, K. Tags: Ocular oncology Source Type: research

Deep phenotyping of PROM1-associated retinal degeneration
Conclusions PROM1-RD comprises a wide range of clinical phenotypes. Depending on the stage of disease, the cone mosaic in PROM1-RD is relatively preserved and can potentially be targeted by cone-directed interventions. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Schliessleder, G., Kalitzeos, A., Kasilian, M., Singh, N., Wang, Z., Hu, Z., Grosspötzl, M., Sadda, S., Wedrich, A., Michaelides, M., Strauss, R. W. Tags: Retina Source Type: research

Outcomes following repair of early-onset versus delayed-onset rhegmatogenous retinal detachments after acute posterior vitreous detachment
Conclusions Delayed-onset RDs occurring ≥6 weeks after initial presentation to a retina specialist with an acute PVD generally had better VA at the time of RD diagnosis and faster post-surgical visual recovery compared with acute-onset RDs diagnosed at the initial presentation. No significant difference in anatomic outcomes was seen between the two groups. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Swaminathan, V. B., Salabati, M., Israilevich, R., Cehelyk, E., Mahmoudzadeh, R., Uhr, J. H., Spirn, M. J., Klufas, M. A., Garg, S. J., Hsu, J. Tags: Retina Source Type: research

Distribution and determinants of choroidal vascularity index in healthy eyes from deep-learning choroidal analysis: a population-based SS-OCT study
Conclusion Using new AI-based choroidal segmentation software, we provided a fast, reliable and objective CVI profile for large-scale samples. Older age and longer AL were independent correlates of choroidal thinning and CVI decline. These factors should be considered when interpreting SS-OCT-based choroidal measurements. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Xuan, M., Li, C., Kong, X., Zhang, J., Wang, W., He, M. Tags: Retina Source Type: research

Deep-learning automated quantification of longitudinal OCT scans demonstrates reduced RPE loss rate, preservation of intact macular area and predictive value of isolated photoreceptor degeneration in geographic atrophy patients receiving C3 inhibition treatment
Conclusion The OCT evidence suggests that pegcetacoplan slows progression of cRORA overall and RPE loss specifically while protecting the remaining photoreceptors and slowing the progression of healthy retina to iRORA. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Fu, D. J., Glinton, S., Lipkova, V., Faes, L., Liefers, B., Zhang, G., Pontikos, N., McKeown, A., Scheibler, L., Patel, P. J., Keane, P. A., Balaskas, K. Tags: Open access, Editor's choice Retina Source Type: research

Fundus topographical distribution patterns of ocular toxoplasmosis
Conclusion The 1° lesions were larger than 2° lesions. The 2° lesions were not significantly closer to fovea than 1° lesions. Temporal quadrant and macular region were found to be densely affected underlining the vision threatening nature of the disease. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Hasanreisoglu, M., Halim, M. S., Cakar Ozdal, P., Ormaechea, M. S., Kesim, C., Ozdemir, H. B., Uludag, G., Sredar, N., Cankurtaran, M., Liu, X., Denniston, A. K., Rudzinski, M. N., Colombero, D. N., Schlaen, B. A., Keane, P. A., Pavesio, C., Nguyen, Q. D. Tags: Inflammatory eye disease Source Type: research