Medicine RSS Search Engine

British Journal of Ophthalmology British Journal of Ophthalmology RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

This page shows you the latest items in this publication.

Morphological characteristics of conjunctival squamous papillomas in relation to human papillomavirus infection
Conclusions We demonstrated that certain clinical and histological features are more frequently associated with HPV infection and that HPV genera other than α-PV are most probably not significant factors in conjunctival papilloma occurrence. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Mlakar, J., Kocjan, B. J., Hosnjak, L., Pizem, J., Beltram, M., Gale, N., Drnovsek-Olup, B., Poljak, M. Tags: Original articles - Laboratory science Source Type: research

Mutation spectrum of CYP1B1 in Chinese patients with primary open-angle glaucoma
Conclusions This study provides a mutation spectrum of CYP1B1 resulting in POAG development in a Chinese population, which may demonstrate an involvement of the gene in a proportion of subjects with POAG and help to improve our understanding of the pathogenesis of CYP1B1-associated POAG. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Gong, B., Qu, C., Li, X., Shi, Y., Lin, Y., Zhou, Y., Shuai, P., Yang, Y., Liu, X., Zhang, D., Yang, Z. Tags: Angle, Intraocular pressure, Glaucoma Original articles - Laboratory science Source Type: research

Structural and functional outcomes of anaesthetic cornea in children
Discussion CA in children is a vision-threatening problem, which has a particularly poor prognosis when associated with facial nerve palsy. Earlier tarsorrhaphy should be considered to help preserve vision in eyes with CA and coexisting facial palsy. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Lambley, R. G., Pereyra-Munoz, N., Parulekar, M., Mireskandari, K., Ali, A. Tags: Cornea, Ocular surface, Neurology, Epidemiology Original articles - Clinical science Source Type: research

Does cognitive impairment influence outcomes from cataract surgery? Results from a 1-year follow-up cohort study
Conclusions Patients with impaired cognition benefit from cataract surgery, but not to the same extent as patients with normal cognition. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Jefferis, J. M., Taylor, J.-P., Clarke, M. P. Tags: Lens and zonules, Open access, Epidemiology Original articles - Clinical science Source Type: research

Clinical outcomes and surgeon assessment after implantation of a new diffractive multifocal toric intraocular lens
Conclusions The implantation of the multifocal toric IOL is a safe procedure that provides a very good visual rehabilitation in eyes with corneal astigmatism. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Kretz, F. T. A., Bastelica, A., Carreras, H., Ferreira, T., Muller, M., Gerl, M., Gerl, R., Saeed, M., Schmickler, S., Auffarth, G. U. Tags: Lens and zonules, Optic nerve, Optics and refraction Original articles - Clinical science Source Type: research

An evaluation of cataract surgery clinical practice guidelines
Conclusions Cataract surgery practice guidelines can be improved by targeting stakeholder involvement, applicability and editorial independence. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Wu, C. M., Wu, A. M., Young, B. K., Wu, D., Chen, A., Margo, C. E., Greenberg, P. B. Tags: Lens and zonules Original articles - Clinical science Source Type: research

Suction posterior capsulorhexis: an audit of 15 years' experience
Conclusions SPC, when performed by an experienced surgeon, appears to achieve better visual outcomes than the CND without causing harm to patients nor adversely affecting biometry accuracy. Use of a hydrophobic acrylic intraocular lens with SPC may avoid the need for subsequent YAG laser therapy. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Hugkulstone, C. E. Tags: Ophthalmologic surgical procedures, Lens and zonules, Epidemiology Original articles - Clinical science Source Type: research

Comparison of conventional versus crossed monovision in pseudophakia
Conclusions The clinical results of the crossed monovision were not significantly different from the results of conventional monovision. Therefore, crossed monovision can also be a valuable option for correcting postoperative presbyopia in patients considering bilateral cataract surgery. Trial registration number KCT0001065 (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Kim, J., Shin, H. J., Kim, H. C., Shin, K. C. Tags: Lens and zonules, Optic nerve, Optics and refraction Original articles - Clinical science Source Type: research

Clinical features and survival among children with retinoblastoma in Uganda
Conclusions Diagnostic delay results in relatively high mortality among children with retinoblastoma in Uganda. There is an urgent need for more effective treatment modalities, particularly chemotherapy, and nationwide efforts to encourage earlier access to medical care. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Waddell, K. M., Kagame, K., Ndamira, A., Twinamasiko, A., Picton, S. V., Simmons, I. G., Johnston, W. T., Newton, R. Tags: Paediatrics, Epidemiology Original articles - Clinical science Source Type: research

Cuban Ocular Toxoplasmosis Epidemiology Study (COTES): incidence and prevalence of ocular toxoplasmosis in Central Cuba
Conclusions This first report describing population-based rates of OT in the Cuban population highlights the importance of patient age as a likely risk factor for OT. Disease rates were found to be highest in females and young to middle-aged adults. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Bustillo, J. L., Diaz, J. D., Pacheco, I. C., Gritz, D. C. Tags: Eye (globe), Epidemiology Original articles - Clinical science Source Type: research

An analysis of IgG4-related disease (IgG4-RD) among idiopathic orbital inflammations and benign lymphoid hyperplasias using two consensus-based diagnostic criteria for IgG4-RD
Conclusions This is the largest review of IgG4 staining among biopsy-confirmed IOI and OBLH. IgG4-ROD accounted for a substantial proportion of OBLH. The prevalence among cases of IOI was considerably reduced when the consensus diagnostic criteria were used in place of the comprehensive diagnostic criteria. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Andrew, N. H., Sladden, N., Kearney, D. J., Selva, D. Tags: Orbit Original articles - Clinical science Source Type: research

Changes following supplementation with lutein and zeaxanthin in retinal function in eyes with early age-related macular degeneration: a randomised, double-blind, placebo-controlled trial
Conclusions Supplementation with lutein and/or zeaxanthin increases MPOD, and supplemental lutein enhances retinal sensitivity, in patients with early AMD. Trial registration number Clinicaltrials.gov NCT10528605. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Huang, Y.-M., Dou, H.-L., Huang, F.-F., Xu, X.-R., Zou, Z.-Y., Lu, X.-R., Lin, X.-M. Tags: Retina, Editor's choice Original articles - Clinical science Source Type: research

Severity of coronary artery disease is independently associated with the frequency of early age-related macular degeneration
Conclusions Severity of coronary stenosis and the presence of stenotic lesions were independently associated with early AMD. These findings could have potential clinical significance as they suggest that individuals with evidence of CAD may be screened for early AMD. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Wang, S. B., Mitchell, P., Chiha, J., Liew, G., Plant, A. J. H., Thiagalingam, A., Burlutsky, G., Gopinath, B. Tags: Retina Original articles - Clinical science Source Type: research

Outcomes of persistently active neovascular age-related macular degeneration treated with VEGF inhibitors: observational study data
Conclusions Persistent activity of neovascular lesions during 12 months after starting intravitreal therapy was not associated with worse visual outcomes in this observational study of AMD. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Barthelmes, D., Walton, R., Campain, A. E., Simpson, J. M., Arnold, J. J., McAllister, I. L., Guymer, R. H., Hunyor, A. P., Essex, R. W., Morlet, N., Gillies, M. C., for the Fight Retinal Blindness! Project Investigators Tags: Choroid, Retina, Vision, Neurology, Epidemiology Original articles - Clinical science Source Type: research

Comparison of choroidal thicknesses using swept source and spectral domain optical coherence tomography in diseased and normal eyes
Conclusions Subfoveal choroidal thickness measurements are comparable between DRI OCT-1 and Spectralis OCT. The presence of retinal disease increases the variability of choroidal thickness measurements between OCT devices. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Tan, C. S. H., Ngo, W. K., Cheong, K. X. Tags: Retina, Epidemiology Original articles - Clinical science Source Type: research

Rate and timing of spontaneous resolution in a vitreomacular traction group: Should the role of watchful waiting be re-evaluated as an alternative to Ocriplasmin therapy?
Conclusions A shorter follow-up might underestimate the incidence of spontaneous VMT resolution as the functional outcome of watchful waiting. The likelihood of resolution does not seem to decrease after 12 months. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Dimopoulos, S., Bartz-Schmidt, K.-U., Gelisken, F., Januschowski, K., Ziemssen, F. Tags: Retina, Epidemiology Original articles - Clinical science Source Type: research

Functional centre of the upper eyelid: the optimal point for eyelid lifting in ptosis surgery
Conclusions The functional eyelid centre was located slightly temporal to the mid-pupillary line. A better eyelid contour in ptosis surgery is produced when eyelid lifting is centred around the functional eyelid centre. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Kim, C. Y., Son, B. J., Lee, S. Y. Tags: Original articles - Clinical science Source Type: research

Long-term outcome of prismatic correction in children with consecutive esotropia after bilateral lateral rectus recession
Conclusions In patients with consecutive esotropia after BLR recession, the angle of esodeviation continuously decreased and 82% were weaned off prism glasses after 3 years. Prismatic correction achieves good motor outcome while maintaining a favourable sensory status in most patients with consecutive esotropia after BLR recession. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Lee, E. K., Yang, H. K., Hwang, J.-M. Tags: Paediatrics, Muscles, Neurology Original articles - Clinical science Source Type: research

In vivo confocal microscopy as a novel and reliable tool for the diagnosis of Demodex eyelid infestation
Conclusions IVCM is an efficient and reliable tool for the diagnosis of eyelid mite infestation and may also provide an evaluation of MGs. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Randon, M., Liang, H., El Hamdaoui, M., Tahiri, R., Batellier, L., Denoyer, A., Labbe, A., Baudouin, C. Tags: Eye Lids, Lacrimal gland, Tears Original articles - Clinical science Source Type: research

Ganglion cell and inner plexiform layer thickness determined by spectral domain optical coherence tomography in patients with brain lesions
Conclusions Our results suggest that various kinds of brain lesions with different locations show considerable reduction in GCIPL thickness. Thickness of the GCIPL performed better than conventional pRNFL thickness for the diagnosis of retinal ganglion cell damage induced by brains lesions. The pattern of GCIPL loss may be of particular usefulness in recognising a potential intracranial lesion in cases suspected of having normal-tension glaucoma. GCIPL thickness determined by OCT can be an early and useful marker to estimate the status of the visual pathway in various brain lesions. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Moon, H., Yoon, J. Y., Lim, H. T., Sung, K. R. Tags: Angle, Intraocular pressure, Glaucoma, Epidemiology Original articles - Clinical science Source Type: research

The effect of hypercapnia on the sensitivity to flicker defined stimuli
Conclusions As CO2 levels were increased in healthy young individuals, there was an associated increase in visual sensitivity that was only significant for HEP-FDF stimuli, highlighting the different mechanisms involved in processing each of HEP-FDF and Matrix-FDT stimuli. Mean visual sensitivity outcomes were found to be similar for normocapnia and hypercapnia suggesting that a capability to compensate for a mild and stable increase in systemic CO2 levels may exist. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Shahidi, A. M., Hudson, C., Patel, S. R., Flanagan, J. G. Tags: Original articles - Clinical science Source Type: research

Reproducibility of retinal oxygen saturation in normal and treated glaucomatous eyes
Conclusions Retinal oximetry measurements using SRO are highly reproducible in both treated glaucomatous and normal eyes. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Goharian, I., Iverson, S. M., Ruiz, R. C., Kishor, K., Greenfield, D. S., Sehi, M. Tags: Angle, Intraocular pressure, Glaucoma Original articles - Clinical science Source Type: research

Service innovation in glaucoma management: using a web-based electronic patient record to facilitate virtual specialist supervision of a shared care glaucoma programme
Conclusions Employing technicians and optometrists to triage glaucoma patients into groups defined by risk of blindness allows higher risk patients to be directed to a glaucoma specialist. Virtual review allows the glaucoma specialist to remain in overall control while reducing the risk that patients are treated or followed-up unnecessarily. Demand for glaucoma appointments can be reduced allowing scarce medical resources to be directed to patients most in need. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Wright, H. R., Diamond, J. P. Tags: Angle, Intraocular pressure, Vision, Open access, Neurology, Glaucoma Original articles - Clinical science Source Type: research

Recent trends in glaucoma surgery in Scotland, England and Wales
Conclusions Trabeculectomy is the most commonly performed glaucoma operation. Aqueous shunts are rapidly increasing in the surgical management of glaucoma. During the study period, the ratio of trabeculectomy to aqueous shunts has reversed in the younger age group (0–14 years). Rates of cyclocyrotherapy to the ciliary body have dramatically declined while laser photocoagulation to the ciliary body is gaining wider acceptability. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Murphy, C., Ogston, S., Cobb, C., MacEwen, C. Tags: Ophthalmologic surgical procedures, Angle, Intraocular pressure, Glaucoma Original articles - Clinical science Source Type: research

Iris mattress suture: a technique for sectoral iris defect repair
We describe an adaptation of techniques to address a case of 2.5 clock hours of sectoral iris tissue defect. Our method combines Siepser's modified closed-chamber sliding knot technique with the placement of a double-armed iris mattress suture to approximate iris tissue to the scleral wall and thereby create a pseudo-iris root. This technique reduces glare and achieves a cosmetic outcome for the patient. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Tsao, S. W., Holz, H. A. Tags: Innovations Source Type: research

Ranibizumab in retinal vein occlusion: treatment recommendations by an expert panel
Retinal vein occlusion (RVO) is a common cause of retinal vascular disease, resulting in potentially irreversible loss of vision despite the existence of several therapeutic options. The humanised monoclonal antibody fragment ranibizumab binds to and inhibits vascular endothelial growth factor, a key driver of macular oedema in RVO. In 2010, ranibizumab was approved in the USA for the treatment of macular oedema in RVO and, in 2011, ranibizumab was approved in the European Union for the treatment of visual impairment caused by macular oedema secondary to RVO in branch and central RVO. Ranibizumab provides an additional the...
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Gerding, H., Mones, J., Tadayoni, R., Boscia, F., Pearce, I., Priglinger, S. Tags: Retina, Open access Review Source Type: research

Myopic choroidal neovascularisation: current concepts and update on clinical management
Choroidal neovascularisation (CNV) is a common vision-threatening complication of myopia and pathological myopia. Despite significant advances in understanding the epidemiology, pathogenesis and natural history of myopic CNV, there is no standard definition of myopic CNV and its relationship to axial length and other myopic degenerative changes. Several treatments are available to ophthalmologists, but with the advent of new therapies there is a need for further consensus and clinical management recommendations. Verteporfin photodynamic therapy has been an established treatment for subfoveal myopic CNV for many years, but ...
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Wong, T. Y., Ohno-Matsui, K., Leveziel, N., Holz, F. G., Lai, T. Y., Yu, H. G., Lanzetta, P., Chen, Y., Tufail, A. Tags: Choroid, Optic nerve, Open access, Optics and refraction, Epidemiology Review Source Type: research

Screening for retinopathy of prematurity (ROP) using wide-angle digital retinal photography by non-ophthalmologists: a systematic review
Retinopathy of prematurity (ROP) is one of the leading and preventable causes of blindness. The investigation of choice for diagnosing ROP is binocular indirect ophthalmoscope (BIO) done by ophthalmologists. Since the number of ophthalmologists available to do BIO examination is limited, especially in developing countries, there is a need for an alternate, cheap, reliable and feasible test. Telemedicine imaging with Digital Retinal Photography (DRP) is one such alternate diagnostic test which can be performed easily by non-ophthalmologists, with adequate training. Our objective was to conduct a systematic review to evaluat...
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Athikarisamy, S. E., Patole, S., Lam, G. C., Dunstan, C., Rao, S. Tags: Public health, Retina, Vision, Neurology, Epidemiology Review Source Type: research

Highlights from this issue
In this study of normal individuals, an increase flicker sensitivity was observed with higher CO2 levels. Sung et al (see (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 18, 2015 Category: Opthalmology Authors: Barton, K., Chodosh, J., Jonas, J. Tags: At a glance Source Type: research

Safety profile of accelerated corneal cross-linking versus conventional cross-linking: a comparative study on ex vivo-cultured limbal epithelial cells
Conclusions The 30 mW UV-A irradiation used in ACXL appears to be safe on cultured LECs in comparison with 3 mW used in CXL. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Shetty, R., Matalia, H., Nuijts, R., Subramani, M., Dhamodaran, K., Pandian, R., Jayadev, C., Das, D. Tags: Original articles - Laboratory science Source Type: research

Use of human serum for human corneal endothelial cell culture
Conclusions HS-SM was similar to FBS-SM for HCEC culture when assessed by cell morphology, proliferation and protein/gene expression. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Vianna, L. M. M., Kallay, L., Toyono, T., Belfort, R., Holiman, J. D., Jun, A. S. Tags: Original articles - Laboratory science Source Type: research

Changes in angle of optic nerve and angle of ocular orbit with increasing age in Japanese children
Conclusions Because the opening angle of the orbit decreased significantly with increasing age, this factor must be considered when diagnosing and treating strabismus in children. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Tsukitome, H., Hatsukawa, Y., Morimitsu, T., Yagasaki, T., Kondo, M. Tags: Muscles, Open access, Neurology Original articles - Clinical science Source Type: research

Outcomes of ab interno trabeculectomy with the trabectome after failed trabeculectomy
Conclusions Both AIT and phaco-AIT showed a reduction in IOP and medication use after 1 year, suggesting that AIT with or without cataract surgery is a safe and effective option following failed trabeculectomy. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Bussel, I. I., Kaplowitz, K., Schuman, J. S., Loewen, N. A., Trabectome Study Group Tags: Ophthalmologic surgical procedures, Angle, Intraocular pressure, Lens and zonules, Open access, Glaucoma Original articles - Clinical science Source Type: research

Swimming goggle wear is not associated with an increased prevalence of glaucoma
Conclusions These findings suggest that frequently wearing swim goggles does not lead to an increased risk of glaucoma over time in adults. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Franchina, M., Yazar, S., Booth, L., Wan, S. L., Cox, K., Kang, M. H., Hewitt, A. W., Mackey, D. A. Tags: Angle, Intraocular pressure, Glaucoma Original articles - Clinical science Source Type: research

Severity of acute ocular involvement is independently associated with time to resolution of ocular disease in toxic epidermal necrolysis patients
Conclusions Grading of acute ocular disease severity does not reflect systemic disease severity and is significantly associated with resolution and time to resolution of ocular involvement in TEN. The high rate of ocular involvement in patients with TEN and relatively large proportion of patients with active disease on discharge reiterates the need for constant ophthalmological monitoring of these patients. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Heng, J. S., Malik, N., Joshi, N., Hayes, M., Jones, I., Fuller, L. C., Vizcaychipi, M. P. Tags: Original articles - Clinical science Source Type: research

A prospective, randomised comparison of probing versus bicanalicular silastic intubation for congenital nasolacrimal duct obstruction
Conclusions Probing for simple CNLDO in young children is adequate. Bicanalicular silastic intubation seems to have a role in achieving successful outcomes in complex CNLDO. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Al-Faky, Y. H., Mousa, A., Kalantan, H., Al-Otaibi, A., Alodan, H., Alsuhaibani, A. H. Tags: Paediatrics Original articles - Clinical science Source Type: research

The effects of absence of stereopsis on performance of a simulated surgical task in two-dimensional and three-dimensional viewing conditions
Conclusions High-grade stereopsis confers an advantage when performing a fine motor task under direct vision. However, stereopsis does not appear advantageous to task performance under 2D viewing conditions, such as in video-assisted surgery. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Bloch, E., Uddin, N., Gannon, L., Rantell, K., Jain, S. Tags: Open access Original articles - Clinical science Source Type: research

Face-down positioning versus non-supine positioning in macular hole surgery
Conclusions Results from consistent FTMH repair indicate similar anatomical success rates in FDP and NSP groups, suggesting that FDP is unnecessary. Objective monitoring of positioning would be beneficial in future FTMH studies to be able to adjust for positioning protocol compliance. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Alberti, M., la Cour, M. Tags: Ophthalmologic surgical procedures, Retina Original articles - Clinical science Source Type: research

Transpalpebral proton beam radiotherapy of choroidal melanoma
Conclusions Transpalpebral PBR of choroidal melanoma avoids eyelid and ocular surface complications without increasing failure of local tumour control. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Konstantinidis, L., Roberts, D., Errington, R. D., Kacperek, A., Heimann, H., Damato, B. Tags: Original articles - Clinical science Source Type: research

The risk of acute coronary syndrome after retinal artery occlusion: a population-based cohort study
Conclusions We found that RAO increased the risk for ACS. We recommend thorough follow-up cardiovascular examinations and medical prevention for ACS in patients following RAO. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Chang, Y.-S., Chu, C.-C., Weng, S.-F., Chang, C., Wang, J.-J., Jan, R.-L. Tags: Retina, Epidemiology Original articles - Clinical science Source Type: research

Multi-country real-life experience of anti-vascular endothelial growth factor therapy for wet age-related macular degeneration
Conclusions In clinical practice, fewer injections are administered than in clinical trials. Anti-VEGF treatment resulted in an initial improvement in visual acuity; however, this was not maintained over time. Trial registration number NCT01447043. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Holz, F. G., Tadayoni, R., Beatty, S., Berger, A., Cereda, M. G., Cortez, R., Hoyng, C. B., Hykin, P., Staurenghi, G., Heldner, S., Bogumil, T., Heah, T., Sivaprasad, S. Tags: Retina, Open access, Editor's choice Original articles - Clinical science Source Type: research

Topical bromfenac reduces the frequency of intravitreal bevacizumab in patients with branch retinal vein occlusion
Conclusions Although topical bromfenac during IVB therapy in eyes with ME secondary to BRVO did not affect the visual prognosis, it had the advantage of reducing the number of injections. Trial registration number UMIN 14929. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Shimura, M., Yasuda, K. Tags: Retina, Epidemiology Original articles - Clinical science Source Type: research

Sequential therapy with ranibizumab and dexamethasone intravitreal implant is better than dexamethasone monotherapy for macular oedema due to retinal vein occlusion
Conclusions Sequential therapy was found to be more effective than dexamethasone monotherapy in treating MO due to RVO. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Iu, L. P., Zhao, P., Yeung, I. Y., Fung, N. S., Lee, J. W., Wong, R. L., Chong, V., Wong, I. Y. Tags: Retina Original articles - Clinical science Source Type: research

Characterisation of uveitis in association with multiple sclerosis
Conclusions Uveitis with MS generally presents as intermediate uveitis with a minority presenting with anterior uveitis. Patients are significantly older and more likely to be women than patients with idiopathic intermediate uveitis. The visual prognosis is generally favourable. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Messenger, W., Hildebrandt, L., Mackensen, F., Suhler, E., Becker, M., Rosenbaum, J. T. Tags: Choroid, Ciliary body, Neurology Original articles - Clinical science Source Type: research

Oral azithromycin versus doxycycline in meibomian gland dysfunction: a randomised double-masked open-label clinical trial
Conclusions Although both oral azithromycin and doxycycline improved the symptoms of MGD, 5-day oral azithromycin is recommended for its better effect on improving the signs, better overall clinical response and shorter duration of treatment. Trial registration number NCT01783860. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Kashkouli, M. B., Fazel, A. J., Kiavash, V., Nojomi, M., Ghiasian, L. Tags: Original articles - Clinical science Source Type: research

Intrastromal voriconazole for deep recalcitrant fungal keratitis: a case series
Conclusions Targeted delivery of voriconazole by intrastromal injection (50 µg/0.1 mL) is a safe and effective way to treat deep recalcitrant fungal keratitis, though some may need repeated injections. Fusarium keratitis may show suboptimal response but this needs further study. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Kalaiselvi, G., Narayana, S., Krishnan, T., Sengupta, S. Tags: Cornea, Eye (globe), Ocular surface Original articles - Clinical science Source Type: research

Trends in bacterial and fungal keratitis in South India, 2002-2012
Conclusions At a tertiary eye care centre in South India, there has been a reduction in the numbers of smear-positive bacterial keratitis over the past 11 years. This decline likely reflects economic development in India and increased access to antibiotics. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Lalitha, P., Prajna, N. V., Manoharan, G., Srinivasan, M., Mascarenhas, J., Das, M., D'Silva, S. S., Porco, T. C., Keenan, J. D. Tags: Public health, Cornea, Eye (globe), Ocular surface Original articles - Clinical science Source Type: research

Measurement of lens density using Scheimpflug imaging system as a screening test in the field of health examination for age-related cataract
Conclusions The Pentacam ImageJ method provided objective measurements to evaluate cataracts needing surgery. The method has the potential to be generally applied in the field of health examination and is effective in screening patients with cataract. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Lim, D. H., Kim, T. H., Chung, E.-S., Chung, T.-Y. Tags: Lens and zonules, Epidemiology Original articles - Clinical science Source Type: research

Three-year follow-up of posterior chamber toric phakic intraocular lens implantation for the correction of high myopic astigmatism in eyes with keratoconus
Conclusions Toric ICL implantation is beneficial according to measures of safety, efficacy, predictability and stability for the correction of refractive errors for keratoconus during a 3-year observation period. The disease did not progress even in the late-postoperative period, suggesting the viability of this procedure as a surgical option for the treatment of such eyes. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Kamiya, K., Shimizu, K., Kobashi, H., Igarashi, A., Komatsu, M., Nakamura, A., Kojima, T., Nakamura, T. Tags: Cornea, Ocular surface, Optic nerve, Optics and refraction Original articles - Clinical science Source Type: research

Intrastromal femtosecond laser surgical compensation of presbyopia with six intrastromal ring cuts: 3-year results
Conclusions INTRACOR with a modified pattern improved UNVA in all patients over a 36-month follow-up period. The possibility of reduced CDVA underlines the need for careful patient selection. Trial registration number NCT00928122. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 20, 2015 Category: Opthalmology Authors: Khoramnia, R., Fitting, A., Rabsilber, T. M., Thomas, B. C., Auffarth, G. U., Holzer, M. P. Tags: Optic nerve, Optics and refraction Original articles - Clinical science Source Type: research