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Journal of Endodontics

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Polymorphism of the CD14 and TLR4 Genes and Post-treatment Apical Periodontitis
Conclusions: Data from the present study suggest that polymorphisms in the CD14 and TLR4 genes do not influence the response to endodontic treatment of teeth with apical periodontitis. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Isabela N. Rôças, José F. Siqueira, Camila A. Del Aguila, José C. Provenzano, Bianca P.S. Guilherme, Lucio S. Gonçalves Tags: Clinical Research Source Type: research

A Standardized Novel Method to Measure Radiographic Root Changes after Endodontic Therapy in Immature Teeth
Conclusions: These results suggest that RRA is a valid measure to assess radiographic outcomes in endodontically treated immature teeth, and RRA should be useful in future clinical studies of regenerative endodontic outcomes. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Natasha M. Flake, Jennifer L. Gibbs, Anibal Diogenes, Kenneth M. Hargreaves, Asma A. Khan Tags: Clinical Research Source Type: research

Histologic and Micro–Computed Tomographic Analyses of Replanted Teeth Stored in Different Kind of Media
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Manuella Verdinelli de Paula Reis, Camilla Christian Gomes Moura, Priscilla Barbosa Ferreira Soares, Graziela Bianchi Leoni, Manoel Damião Souza-Neto, Darceny Zanetta Barbosa, Carlos José Soares Tags: Biology Source Type: research

Role of the P38 Pathway in Calcium Silicate Cement–induced Cell Viability and Angiogenesis-related Proteins of Human Dental Pulp Cell
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Ming-Yung Chou, Chia-Tze Kao, Chi-Jr Hung, Tsui-Hsien Huang, Shu-Ching Huang, Ming-You Shie, Buor-Chang Wu Source Type: research

Visualization of Removal of Trapped Air from the Apical Region of the Straight Root Canal Models Generating 2-phase Intermittent Counter Flow during Ultrasonically Activated Irrigation
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Harry Huiz Peeters, Bernard Iskandar, Ketut Suardita, Djoko Suharto Source Type: research

Histologic and Micro–Computed Tomographic Analyses of Replanted Teeth Stored in Different Kind of Media
Conclusions: Additionally, this study showed that the combined use of histologic analysis and μCT is a promising method to better identify tooth resorption and the repair process and to evaluate the total extension of the periodontium. CW as a storage medium is a promising transport media for avulsed teeth. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Manuella Verdinelli de Paula Reis, Camilla Christian Gomes Moura, Priscilla Barbosa Ferreira Soares, Graziela Bianchi Leoni, Manoel Damião Souza-Neto, Darceny Zanetta Barbosa, Carlos José Soares Tags: Biology Source Type: research

Regaining Apical Patency after Obturation with Gutta-percha and a Sealer Containing Mineral Trioxide Aggregate
Conclusions: Chloroform, Endosolv E, and Eucalyptol soften GP and MTA Fillapex sufficiently to aid in re-establishing apical patency during endodontic retreatment. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Matthew T. Carpenter, Stephanie J. Sidow, Kimberly W. Lindsey, Augustine Chuang, James C. McPherson Tags: Technology Source Type: research

Age and Timing of Pulp Extirpation as Major Factors Associated with Inflammatory Root Resorption in Replanted Permanent Teeth
Conclusions: The risk of mature teeth developing severe IERR before the onset of endodontic therapy was directly affected by the timing of the pulpectomy and was inversely proportional to age. Systemic antibiotic therapy use had no effect on the occurrence and severity of IERR in mature teeth. The occurrence of RERR before the onset of endodontic treatment stimulates further investigations of the early human host response to trauma and subsequent infection. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Juliana Vilela Bastos, Maria Ilma de Souza Côrtes, Eugenio Marcos Andrade Goulart, Enrico Antonio Colosimo, Ricardo Santiago Gomez, Walderez Ornelas Dutra Tags: Clinical Research Source Type: research

A Comparative Investigation of Cone-beam Computed Tomography and Periapical Radiography in the Diagnosis of a Healthy Periapex
Conclusions: Teeth with necrotic pulps were more likely to have PDL widening, but the PDL space of a healthy tooth demonstrated significant variation when examined by CBCT. The radiographic interpretation of health and disease on CBCT must be further investigated before usage in outcome or epidemiologic investigations. This research questions the traditional radiographic interpretation of the PDL space. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 18, 2013 Category: Dentistry Authors: Oliver Pope, Chankhrit Sathorn, Peter Parashos Tags: Clinical Research Source Type: research

Evaluation of Root Canal Configuration of Maxillary Molars in a Brazilian Population Using Cone-beam Computed Tomographic Imaging: An In Vivo Study
Conclusions: Mesiobuccal roots of maxillary molar teeth had more variation in their canal system than the distobuccal or palatal roots. The root canal configuration of the maxillary second molars was more variable than the first molars in a Brazilian population. CBCT imaging is a clinically useful tool for endodontic diagnosis and treatment planning. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Emmanuel João Nogueira Leal Silva, Yuri Nejaim, Amaro I.V. Silva, Francisco Haiter-Neto, Alexandre A. Zaia, Nestor Cohenca Tags: Clinical Research Source Type: research

Morphology and Microhardness of Dentin at the Furcation Area of Mandibular Molars
Conclusions: Dentin microhardness at the furcation area is uniform in its 3 vertical axes, but the inner dentin layer is harder than the outer layer. The dentinal tubules follow a centripetal direction toward the inner layer, in which dentin is much more mineralized. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Antonio M. Cruz-Filho, Luis Eduardo Souza Flamini, Jesus Djalma Pécora Tags: Technology Source Type: research

Ionic Extraction of a Novel Nano-sized Bioactive Glass Enhances Differentiation and Mineralization of Human Dental Pulp Cells
Conclusions: Compared with regular BG, the novel nano-58S BG can induce the differentiation and mineralization of hDPCs more efficiently and might be a better potential candidate for dentin-pulp complex regeneration. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Weiyu Gong, Zhiwei Huang, Yanmei Dong, Yehua Gan, Shenglin Li, Xuejun Gao, Xiaofeng Chen Tags: Biology Source Type: research

Human Cytomegalovirus and Epstein-Barr Virus in Etiopathogenesis of Apical Periodontitis: A Systematic Review
Conclusions: The findings of HCMV and EBV transcripts in apical periodontitis were controversial among the included studies. Herpesviruses were common in symptomatic and large-size periapical lesions, but such results failed to reach statistical significance. Further studies, including those based on an experimental animal model, should provide more data on herpesviruses as a factor in the pathogenesis of periapical inflammation. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Aleksandar Jakovljevic, Miroslav Andric Tags: Review Article Source Type: research

Orbital, Mediastinal, and Cervicofacial Subcutaneous Emphysema after Endodontic Retreatment of a Mandibular Premolar: A Case Report
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Gregory K. An, Boris Zats, Marc Kunin Source Type: research

Shrinkage of Backfill Gutta-percha upon Cooling
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Silvio Lottanti, Tobias T. Tauböck, Matthias Zehnder Tags: Technology Source Type: research

Extension of Bactericidal Effect of Sodium Hypochlorite into Dentinal Tubules
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Debbie T.S. Wong, Gary S.P. Cheung Source Type: research

Comparative Study of Different Novel Nickel-Titanium Rotary Systems for Root Canal Preparation in Severely Curved Root Canals
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Ismail Davut Capar, Huseyin Ertas, Evren Ok, Hakan Arslan, Elif Tarim Ertas Source Type: research

The Effect of Different Final Irrigant Activation Techniques on the Bond Strength of an Epoxy Resin–based Endodontic Sealer: A Preliminary Study
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Hüseyin Sinan Topçuoğlu, Öznur Tuncay, Sezer Demirbuga, Asiye Nur Dinçer, Hakan Arslan Source Type: research

Shrinkage of Backfill Gutta-percha upon Cooling
Conclusions: Gutta-percha designed for thermoplastic application shrinks quickly and extensively upon cooling. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Silvio Lottanti, Tobias T. Tauböck, Matthias Zehnder Tags: Technology Source Type: research

Bending Resistance and Dynamic and Static Cyclic Fatigue Life of Reciproc and WaveOne Large Instruments
Conclusions: Reciproc R40 instruments resisted dynamic and static cyclic fatigue significantly more than WaveOne Large instruments. Furthermore, WaveOne instruments presented significantly less flexibility than Reciproc. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Gustavo De-Deus, Victor Talarico Leal Vieira, Emmanuel João Nogueira da Silva, Helio Lopes, Carlos Nelson Elias, Edson Jorge Moreira Tags: Technology Source Type: research

Orthokeratinized Odontogenic Cysts Presenting as a Periapical Lesion: Report of a Case and Literature Review
Conclusions: The presence of keratin in radicular lesions must be carefully evaluated to eliminate the diagnosis of lesions with more aggressive behavior, such as an OOC or even a keratocystic odontogenic tumor. Hence, histopathologic examination is mandatory to confirm the type of lesion and to differentiate other pathologic conditions, therefore establishing patients' prognoses precisely. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: João Paulo Silva Servato, Sérgio Vitorino Cardoso, Marcelo Caetano Parreira da Silva, Mirna Scalon Cordeiro, Paulo Rogério de Faria, Adriano Mota Loyola Tags: Case Report/Clinical Techniques Source Type: research

Effect of Different Final Irrigation Methods on the Removal of Calcium Hydroxide from an Artificial Standardized Groove in the Apical Third of Root Canals
Abstract: Introduction: The aim of this study was to compare the efficacy of conventional syringe, ultrasonic, EndoVac (Discus Dental, Culver City, CA), and Self-Adjusting File (SAF) (Re-Dent-Nova, Ra'nana, Israel) irrigation systems in removing calcium hydroxide (Ca[OH]2) from simulated root canal irregularities.Methods: The root canals of 88 extracted single-rooted teeth were prepared using ProTaper rotary instruments (Dentsply Maillefer, Ballagiues, Switzerland) up to size F4. The roots were split longitudinally, and a standardized groove was prepared in the apical part of 1 segment. The root halves were reassembled, a...
Source: Journal of Endodontics - November 11, 2013 Category: Dentistry Authors: Ismail Davut Capar, Erhan Ozcan, Hakan Arslan, Huseyin Ertas, Hale Ari Aydinbelge Tags: Technology Source Type: research

The Effect of Octamer-binding Transcription Factor 4B1 on microRNA Signals in Human Dental Pulp Cells with Inflammatory Response
Conclusions: Oct-4B1 may play a critical role in the inflammatory response of DPCs through interaction with miRNAs. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 8, 2013 Category: Dentistry Authors: Qianyin Kong, Lu Liu, Yijun Huang, Fang Zhang, Xi Wei, Junqi Ling Tags: Biology Source Type: research

Role of MiR-424 on Angiogenic Potential in Human Dental Pulp Cells
Conclusions: This study demonstrated that miR-424 may play a negative role in regulating endothelial differentiation of hDPCs, and inhibition of miR-424 may contribute to dental pulp repair and regeneration. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 8, 2013 Category: Dentistry Authors: Wei Liu, Qimei Gong, Junqi Ling, Wen Zhang, Zhaohui Liu, Jingjing Quan Tags: Biology Source Type: research

Imbalance of Interleukin-17+ T-cell and Foxp3+ Regulatory T-cell Dynamics in Rat Periapical Lesions
Conclusions: Our findings imply the imbalance of IL-17+ T cell and Foxp3+ Treg cell dynamics in induced periapical lesions, which may play an important role in periapical lesion progression. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 8, 2013 Category: Dentistry Authors: Shasha Yang, Lingxin Zhu, Lan Xiao, Ya Shen, Li Wang, Bin Peng, Markus Haapasalo Tags: Biology Source Type: research

Regenerative Capacity of Human Dental Pulp and Apical Papilla Cells after Treatment with a 3-Antibiotic Mixture
Conclusions: One milligram per milliliter of 3Mix had strong toxicity to DPCs/APCs when applied for 7 days, whereas 0.39 μg/mL 3Mix showed no toxicity but still affected cell proliferation and mineralization potential. However, no differences in dentinogenic gene expressions were observed between the 3Mix-treated and untreated groups. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 8, 2013 Category: Dentistry Authors: Panupat Phumpatrakom, Tanida Srisuwan Tags: Biology Source Type: research

Nonendodontic Lesions Misdiagnosed as Apical Periodontitis Lesions: Series of Case Reports and Review of Literature
Conclusions: Clinical and radiologic aspects as well as the analysis of the patients' medical history, pulp vitality tests, and aspiration are essential tools for developing a correct diagnosis of periapical lesions of endodontic origin. However, if the instruments mentioned earlier indicate a lesion of nonendodontic origin, a biopsy and subsequent histopathological analysis are mandatory. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 7, 2013 Category: Dentistry Authors: Flavia Sirotheau Corrêa Pontes, Felipe Paiva Fonseca, Adriana Souza de Jesus, Ana Carolina Garcia Alves, Leila Marques Araújo, Liliane Silva do Nascimento, Hélder Antônio Rebelo Pontes Tags: Clinical Research Source Type: research

Cytotoxicity Evaluation of a New Resin-based Hybrid Root Canal Sealer: An In Vitro Study
Conclusions: These data support the possible use of XT as an endodontic sealer. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 4, 2013 Category: Dentistry Authors: Elisabetta Cotti, Vittorio Petreucic, Dino Re, Gabriella Simbula Tags: Technology Source Type: research

Effects of ProRoot MTA, Bioaggregate, and Micromega MTA on Odontoblastic Differentiation in Human Dental Pulp Cells
Conclusions: Collectively, the biocompatibility, odontogenic potentials, and inflammatory response of BA and MMTA are equal to those of PMTA and superior to those of IRM. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 4, 2013 Category: Dentistry Authors: Seok-Woo Chang, So-Youn Lee, Kee-Yeon Kum, Eun-Cheol Kim Tags: Technology Source Type: research

Distribution of Mast Cells and Macrophages and Expression of Interleukin-6 in Periapical Cysts
Conclusions: The results reinforced the participation of mast cells and macrophages in the pathogenesis of periapical cysts and suggested that IL-6 is not the major bone resorption mediator in larger periapical cysts. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 4, 2013 Category: Dentistry Authors: Igor Vieira Bracks, Luciana Armada, Lúcio Souza Gonçalves, Fábio Ramôa Pires Tags: Biology Source Type: research

Detection of Various Anatomic Patterns of Root Canals in Mandibular Incisors Using Digital Periapical Radiography, 3 Cone-beam Computed Tomographic Scanners, and Micro–Computed Tomographic Imaging
Conclusions: Double-exposure digital PA radiography for mandibular incisors is sufficient for the identification of the number of root canals. All CBCT devices showed improved accuracy in the identification of single root canal anatomy when a narrow canal was present. However, the identification of oval canals was improved only with the NewTom CBCT device. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 4, 2013 Category: Dentistry Authors: Luciana Maria Paes da Silva Ramos Fernandes, Dwight Rice, Ronald Ordinola-Zapata, Ana Lucia Alvares Capelozza, Clovis Monteiro Bramante, David Jaramillo, Heidi Christensen Tags: Clinical Research Source Type: research

Spectrophotometric Analysis of Crown Discoloration Induced by Various Antibiotic Pastes Used in Revascularization
(Source: Journal of Endodontics)
Source: Journal of Endodontics - November 4, 2013 Category: Dentistry Authors: Merve Akcay, Hakan Arslan, Bilal Yasa, Fevzi Kavrık, Elif Yasa Source Type: research

Comparison of the Efficacy of Smear Clear with and without a Canal Brush in Smear Layer and Debris Removal from Instrumented Root Canal Using WaveOne versus ProTaper: A Scanning Electron Microscopic Study
Conclusions: Using the rotary CanalBrush in canals prepared with WaveOne produced the cleanest canal walls, and the WaveOne system gave superior results compared with the ProTaper system. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 4, 2013 Category: Dentistry Authors: Wael H. Kamel, Engy M. Kataia Tags: Technology Source Type: research

Color Stability of White Mineral Trioxide Aggregate in Contact with Hypochlorite Solution
Conclusions: Contact of white MTA and other bismuth-containing materials with sodium hypochlorite solution should be avoided. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 4, 2013 Category: Dentistry Authors: Josette Camilleri Tags: Technology Source Type: research

Investigation of the Effect of Sealer Use on the Heat Generated at the External Root Surface during Root Canal Obturation Using Warm Vertical Compaction Technique with System B Heat Source
Conclusions: It could be concluded that surrounding conditions, such as temperature and humidity, exerted influence on heating dissipation during the continuous wave of the condensation obturation technique and that root canal sealers presented different conductive/isolating properties. Furthermore, the physical and chemical properties of AH Plus were negatively affected by the changes in temperature. (Source: Journal of Endodontics)
Source: Journal of Endodontics - November 1, 2013 Category: Dentistry Authors: Raqueli Viapiana, Juliane Maria Guerreiro-Tanomaru, Mario Tanomaru-Filho, Josette Camilleri Tags: Technology Source Type: research

Cavitation Measurement during Sonic and Ultrasonic Activated Irrigation
Conclusions: Cavitation was shown to occur in UAI at clinically relevant ultrasonic power settings in both straight and curved canals but not around sonically oscillating instruments, driven at their highest frequency. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 30, 2013 Category: Dentistry Authors: Ricardo Macedo, Bram Verhaagen, David Fernandez Rivas, Michel Versluis, Paul Wesselink, Luc van der Sluis Tags: Technology Source Type: research

Comparison between Prescription of Regular or On-demand Ibuprofen on Postoperative Pain after Single-visit Root Canal Treatment of Teeth with Irreversible Pulpitis
Conclusions: In patients who had irreversible pulpitis with no moderate to severe spontaneous pain, prescribing ibuprofen on a regular basis after root canal treatment had no significant effect on pain relief compared with an on-demand regimen up to 48 hours after treatment. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 29, 2013 Category: Dentistry Authors: Masoud Parirokh, Saeedeh Sadr, Nouzar Nakhaee, Paul V. Abbott, Hamed Manochehrifar Tags: CONSORT Randomized Clinical Trial Source Type: research

Influence of Ferrule, Post System, and Length on Biomechanical Behavior of Endodontically Treated Anterior Teeth
Conclusions: Post length influenced only the cast post strain and stress distribution. The ferrule groups always showed more satisfactory stress distribution and fracture resistance. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 29, 2013 Category: Dentistry Authors: Paulo César Freitas Santos-Filho, Crisnicaw Veríssimo, Paulo Vinícius Soares, Rebeca Carniello Saltarelo, Carlos José Soares, Luis Roberto Marcondes Martins Tags: Technology Source Type: research

In Vitro Regulation of CCL3 and CXCL12 by Bacterial By-products Is Dependent on Site of Origin of Human Oral Fibroblasts
Conclusions: EcLPS and EfLTA induced the production of CCL3 and unbalanced the synthesis of CXCL12 in a manner dependent on the specific tissue origin of fibroblasts. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 29, 2013 Category: Dentistry Authors: Carla Renata Sipert, Ana Carolina Morandini, Thiago José Dionísio, Maria Aparecida Andrade Moreira Machado, Sandra Helena Penha Oliveira, Ana Paula Campanelli, Winston Patrick Kuo, Carlos Ferreira Santos Tags: Biology Source Type: research

Effect of Preoperative Acetaminophen/Hydrocodone on the Efficacy of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind, Placebo-controlled Study
Conclusions: A combination dose of 1000 mg acetaminophen/10 mg hydrocodone given 60 minutes before the administration of the IAN block did not result in a statistically significant increase in anesthetic success for mandibular posterior teeth in patients experiencing symptomatic irreversible pulpitis. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 29, 2013 Category: Dentistry Authors: Spencer Fullmer, Melissa Drum, Al Reader, John Nusstein, Mike Beck Tags: CONSORT Randomized Clinical Trial Source Type: research

Influence of Single-file Endodontics on Apical Transportation in Curved Root Canals: An Micro–Computed Tomographic Study
(Source: Journal of Endodontics)
Source: Journal of Endodontics - October 29, 2013 Category: Dentistry Authors: Alanna Junaid, Laila Gonzales Freire, Carlos Eduardo da Silveira Bueno, Isabel Mello, Rodrigo Sanches Cunha Tags: Technology Source Type: research

Influence of Single-file Endodontics on Apical Transportation in Curved Root Canals: An Ex Vivo Micro–Computed Tomographic Study
Conclusions: The results suggest that no difference exists between the WO file system and the conventional multifile TF system when considering apical transportation in curved canals. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 29, 2013 Category: Dentistry Authors: Alanna Junaid, Laila Gonzales Freire, Carlos Eduardo da Silveira Bueno, Isabel Mello, Rodrigo Sanches Cunha Tags: Technology Source Type: research

Not All Electronic Foramen Locators Are Accurate in Teeth with Enlarged Apical Foramina: An In Vitro Comparison of 5 Brands
Conclusions: Foramen diameter did not influence the accuracy of MiniApex, Root ZXII, and Elements Apex Locator EFLs. iPex and Propex II showed decreased accuracy as foramen size increased. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 28, 2013 Category: Dentistry Authors: Eduardo Akisue, Simone Domingues Gratieri, Fernando Branco Barletta, Celso Luiz Caldeira, Renata Grazziotin-Soares, Giulio Gavini Tags: Technology Source Type: research

Proinflammatory Cytokines Induce Stromelysin-1–mediated Cell Proliferation in Dental Pulp Fibroblast-like Cells
Conclusions: Our results showed that proinflammatory cytokine-induced stromelysin-1 regulates cell proliferation and anti-apoptosis in DPFCs in addition to their better documented destructive role in inflammation. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 28, 2013 Category: Dentistry Authors: Hideyuki Yamaguchi, Nobuaki Ozeki, Rie Kawai, Tsuyoshi Tanaka, Taiki Hiyama, Kazuhiko Nakata, Makio Mogi, Hiroshi Nakamura Tags: Biology Source Type: research

Concentration-dependent Effect of Sodium Hypochlorite on Stem Cells of Apical Papilla Survival and Differentiation
Conclusions: Collectively, the results suggest that dentin conditioning with high concentrations of NaOCl has a profound negative effect on the survival and differentiation of SCAPs. However, this effect can be prevented with the use of 1.5% NaOCl followed by 17% EDTA. The inclusion of this irrigation regimen might be beneficial in regenerative endodontic procedures. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 28, 2013 Category: Dentistry Authors: David E. Martin, Jose Flavio A. De Almeida, Michael A. Henry, Zin Z. Khaing, Christine E. Schmidt, Fabricio B. Teixeira, Anibal Diogenes Tags: Biology Source Type: research

Dentinal Damage and Fracture Resistance of Oval Roots Prepared with Single-file Systems Using Different Kinematics
(Source: Journal of Endodontics)
Source: Journal of Endodontics - October 28, 2013 Category: Dentistry Authors: Hend Mahmoud Abou El Nasr, Karim Galal Abd El Kader Source Type: research

Comparison of Alternative Image Reformatting Techniques in Micro–Computed Tomography and Tooth Clearing for Detailed Canal Morphology
Conclusions: The combination of 2D MinIP and 3D volume-rendered images showed the most detailed canal morphology and fine anatomic structures. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 28, 2013 Category: Dentistry Authors: Ki-Wook Lee, Yeun Kim, Hiran Perinpanayagam, Jong-Ki Lee, Yeon-Jee Yoo, Sang-Min Lim, Seok Woo Chang, Byung-Hyun Ha, Qiang Zhu, Kee-Yeon Kum Tags: Technology Source Type: research

Fibrin Gel Improves Tissue Ingrowth and Cell Differentiation in Human Immature Premolars Implanted in Rats
Conclusions: Under the conditions of this study, fibrin gel improved cell infiltration and cell-dentin interaction. Both are necessary for pulp tissue regeneration. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 25, 2013 Category: Dentistry Authors: Nisarat Ruangsawasdi, Matthias Zehnder, Franz E. Weber Tags: Biology Source Type: research

Antibacterial Efficacy of Photosensitizer Functionalized Biopolymeric Nanoparticles in the Presence of Tissue Inhibitors in Root Canal
Conclusions: The inherent antibacterial activity of polycationic chitosan nanoparticles and the singlet oxygen released after photoactivation of RB synergistically provided CSRBnp the potential to achieve significant antibacterial efficacy even in the presence of tissue inhibitors within root canals. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 25, 2013 Category: Dentistry Authors: Annie Shrestha, Anil Kishen Tags: Technology Source Type: research

Histopathological Condition of the Remaining Tissues after Endodontic Infection of Rat Immature Teeth
Conclusions: Vital pulp tissue was observed in the apical third until 60 days and in the vital apical papilla until 90 days of infection in a rat model. (Source: Journal of Endodontics)
Source: Journal of Endodontics - October 25, 2013 Category: Dentistry Authors: Paulo Carvalho Tobias Duarte, João Eduardo Gomes-Filho, Edilson Ervolino, Maria Lúcia Marçal Mazza Sundefeld, Marcelo TadahiroWayama, Carolina Simonetti Lodi, Eloi Dezan-Júnior, Luciano Tavares Angelo Cintra Tags: Technology Source Type: research