Medicine RSS Search Engine

Metabolic Syndrome research Metabolic Syndrome research RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog.subscribe with FeedlySubscribe to this data using Feedly.

This page shows you the latest research publications in this category.

Metabolic syndrome and associated factors in children and adolescents of a brazilian municipality.
Conclusions: The MS prevalence is high in children and adolescents and it is increased in patients with overweight, higher father education, increased serum very-low-density lipoprotein concentrations and a concomitant serum homocysteine and cysteine high levels. PMID: 24679029 [PubMed - as supplied by publisher] (Source: Nutricion Hospitalaria)
Source: Nutricion Hospitalaria - April 2, 2014 Category: Nutrition Authors: Dias Pitangueira JC, Rodrigues Silva L, Portela de Santana ML, Monteiro da Silva MD, De Farias Costa PR, D'Almeida V, De Oliveira Assis AM Tags: Nutr Hosp Source Type: research

Regular Exercise Coupled to Diet Regimen Accelerates Reduction of Hepatic Steatosis and Associated Pathological Conditions in Nonalcoholic Fatty Liver Disease
Metabolic Syndrome and Related Disorders , Vol. 0, No. 0. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - April 2, 2014 Category: Endocrinology Tags: article Source Type: research

Lipolysis inhibition as therapeutic target in the metabolic syndrome
In conclusion, the relationship between meningitis and pituitary apoplexy may be bidirectional. Apoplexy can mimic viral or bacterial meningitis, but meningitis might cause apoplexy, as well. This fact highlights the importance of differential diagnosis when evaluating patients with pituitary adenomas and acute neurological symptoms.A apoplexia é uma síndrome clínica rara, mas potencialmente fatal, caracterizada por infarto isquêmico ou hemorragia em um tumor pituitário. O diagnóstico de apoplexia de tumor pituitário é frequentemente complicado pela natureza inespecífica dos seus sinais e sintomas, que podem simul...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 1, 2014 Category: Endocrinology Source Type: research

Early Changes in the Components of the Metabolic Syndrome in a Group of Smokers After Tobacco Cessation
Metabolic Syndrome and Related Disorders , Vol. 0, No. 0. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - April 1, 2014 Category: Endocrinology Tags: article Source Type: research

The Relation Between Carotid Intima Media Thickness and Serum Osteoprotegerin Levels in Nonalcoholic Fatty Liver Disease
Metabolic Syndrome and Related Disorders , Vol. 0, No. 0. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - April 1, 2014 Category: Endocrinology Tags: article Source Type: research

Aerobic exercise acutely prevents the endothelial dysfunction induced by mental stress among subjects with metabolic syndrome: the role of shear rate
In conclusion, exercise prevented mental stress-induced endothelial dysfunction among subjects with MetS, and an increase in shear rate during exercise mediated this effect. (Source: AJP: Heart and Circulatory Physiology)
Source: AJP: Heart and Circulatory Physiology - April 1, 2014 Category: Cardiology Authors: Sales, A. R. K., Fernandes, I. A., Rocha, N. G., Costa, L. S., Rocha, H. N. M., Mattos, J. D. M., Vianna, L. C., Silva, B. M., Nobrega, A. C. L. Tags: VASCULAR BIOLOGY AND MICROCIRCULATION Source Type: research

Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-{delta} gene
Peroxisome proliferator-activated receptor (PPAR)- is a nuclear hormone receptor that is mainly involved in lipid metabolism. Recent studies have suggested that PPAR- agonists exert vascular protective effects. The present study was designed to characterize vascular function in mice with genetic inactivation of PPAR- in the endothelium. Mice with vascular endothelial cell-specific deletion of the PPAR- gene (ePPAR–/– mice) were generated using loxP/Cre technology. ePPAR–/– mice were normotensive and did not display any sign of metabolic syndrome. Endothelium-dependent relaxations to ACh and endothel...
Source: AJP: Heart and Circulatory Physiology - April 1, 2014 Category: Cardiology Authors: d'Uscio, L. V., He, T., Santhanam, A. V. R., Tai, L.-J., Evans, R. M., Katusic, Z. S. Tags: VASCULAR BIOLOGY AND MICROCIRCULATION Source Type: research

Pd31-01 metabolic syndrome components and prostate cancer risk: results from the reduce study
(Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2014 Category: Urology & Nephrology Authors: Katharine N. Sourbeer, Lauren E. Howard, Gerald L. Andriole, Daniel M. Moreira, Stephen J. Freedland, Adriana C. Vidal Tags: Prostate Cancer: Epidemiology & Natural History I (PD31) Source Type: research

Mp72-02 do the metabolic syndrome and chronic histological changes effect on residual kidney function in living kidney donors?
(Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2014 Category: Urology & Nephrology Authors: Kyung Hwa Choi, Kwang Hyun Kim, Young Eun Yoon, Kwang-suk Lee, Seung Choul Yang, Kyu Ha Huh, Dong Jin Joo, Myoung Soo Kim, Soon Il Kim, Yu Seun Kim, Woong Kyu Han Tags: Transplantation & Vascular Surgery II (MP72) Source Type: research

Pd25-09 non alcoholic fatty liver disease is an independent predictor of moderate-severe lower urinary tract symptoms in metabolic syndrome patients: results from a cross-sectional study
(Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2014 Category: Urology & Nephrology Authors: Giorgio Ivan Russo, Sebastiano Cimino, Vincenzo Favilla, Eugenia Fragalà, Salvatore Privitera, Tommaso Castelli, Sandro La Vignera, Rosita Condorelli, Aldo E. Calogero, Giuseppe Morgia Tags: Benign Prostatic Hyperplasia: Evaluation & Markers (PD25-01) Source Type: research

Mp48-04 predictors of poor response to transdermal testosterone therapy in men with metabolic syndrome
(Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2014 Category: Urology & Nephrology Authors: Ashley Winter, Anthony Marte, Morgan Kelly, Michael Funaro, Peter Schlegel, Darius Paduch Tags: Sexual Function/Dysfunction/Andrology: Medical and Non-surgical (MP48-01) Source Type: research

Mp40-20 the association between metabolic syndrome with tumor size and grade of renal cell carcinoma
(Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2014 Category: Urology & Nephrology Authors: Alper Otunctemur, Suleyman Sahin, Murat Dursun, Huseyin Besiroglu, Ismail Koklu, Mustafa Erkoc, Eyyup Danis, Muammer Bozkurt, Emin Ozbek Tags: Kidney Cancer: Evaluation/Staging IV (MP40) Source Type: research

Mp32-12 completing five years of testosterone treatment leads to progressive weight loss and waist size reduction as well as improvement of metabolic syndrome parameters in men with late onset hypogonadism (loh)
(Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2014 Category: Urology & Nephrology Authors: Dany-Jan Yassin, Aksam Yassin, Peter Hammerer Tags: Sexual Function/Dysfunction/Andrology: Evaluation (MP32) Source Type: research

Mp24-11 gnrh antagonists associate with less weight gain and milder characteristics of the metabolic syndrome and atherosclerosis compared to surgical castration and gnrh analogues in pre-clinical animal model
(Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2014 Category: Urology & Nephrology Authors: Wilhelmina CM. Duivenvoorden, Sarah Hopmans, Geoff Werstuck, Pinthus Jehonathan Tags: Prostate Cancer: Basic Research I (MP24) Source Type: research

Glycotoxins link dementia and metabolic syndrome [Medical Sciences]
Age-associated dementia and Alzheimer’s disease (AD) are currently epidemic. Neither their cause nor connection to the metabolic syndrome (MS) is clear. Suppression of deacetylase survival factor sirtuin 1 (SIRT1), a key host defense, is a central feature of AD. Age-related MS and diabetes are also causally associated with suppressed SIRT1... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 1, 2014 Category: Science Authors: Cai, W., Uribarri, J., Zhu, L., Chen, X., Swamy, S., Zhao, Z., Grosjean, F., Simonaro, C., Kuchel, G. A., Schnaider-Beeri, M., Woodward, M., Striker, G. E., Vlassara, H. Tags: Biological Sciences Source Type: research

Current recommendations: what is the clinician to do?
Menopausal hormone therapy (HT) has complex biologic effects but continues to have an important clinical role in the management of vasomotor and other menopausal symptoms. The rational use of menopausal HT requires balancing the potential benefits and risks of treatment. Findings from the Women's Health Initiative (WHI) and other randomized clinical trials have helped to clarify the benefits and risks of HT and have provided insights to improve decision making. Several clinical characteristics have utility in identifying women for whom benefits of HT are likely to outweigh the risks. Age and time since menopause are strong...
Source: Fertility and Sterility - March 31, 2014 Category: Reproduction Medicine Authors: JoAnn E. Manson Tags: Views and reviews Source Type: research

Synergistic anti-inflammatory effect: simvastatin and pioglitazone reduce inflammatory markers of plasma and epicardial adipose tissue of coronary patients with metabolic syndrome
Conclusions: Pioglitazone, simvastatin or combination treatment substantially reduced EAT and plasma inflammatory markers in CAD and MS patients. These tissue effects may contribute to the control of coronary atherosclerosis progression. (Source: BioMed Central)
Source: BioMed Central - March 31, 2014 Category: Journals (General) Authors: Adriana Ferreira GrossoSérgio Ferreira de OliveiraMaria de HiguchiDesidério FavaratoLuís Alberto DallanProtásio Lemos da Luz Source Type: research

Epidemiology and etiology of benign prostatic hyperplasia and bladder outlet obstruction
Nishant D Patel, J Kellogg ParsonsIndian Journal of Urology 2014 30(2):170-176Benign prostatic hyperplasia (BPH) is a histological diagnosis associated with unregulated proliferation of connective tissue, smooth muscle and glandular epithelium. BPH may compress the urethra and result in anatomic bladder outlet obstruction (BOO); BOO may present as lower urinary tract symptoms (LUTS), infections, retention and other adverse events. BPH and BOO have a significant impact on the health of older men and health-care costs. As the world population ages, the incidence and prevalence of BPH and LUTS have increased rapidly. Although...
Source: Indian Journal of Urology - March 29, 2014 Category: Urology & Nephrology Authors: Nishant D PatelJ Kellogg Parsons Source Type: research

Plasma concentrations of retinol in obese children and adolescents: relationship to metabolic syndrome components
Conclusions: An independent and inverse association between plasma retinol levels and glucose tolerance was observed, suggesting an important contribution of this vitamin in the morbidities associated to obesity in children and adolescents. Objetivo: Evaluar las concentraciones plasmáticas de retinol en niños y adolescentes obesos y relacionarlas con componentes del síndrome metabólico. Métodos: Mediante estudio transversal, se evaluaron 61 niños y adolescentes obesos (escore Z del índice de masa corpórea - ZIMC>+2). Se obtuvieron datos de estadiamento puberal, presión arterial sistémica, peso y estatura para...
Source: Revista Paulista de Pediatria - March 28, 2014 Category: Pediatrics Source Type: research

Metabolic syndrome and insulin resistance in obese adolescents
Conclusions: All body composition indicators, HDL-cholesterol and metabolic syndrome showed correlation with insulin resistance. The BMI was the most effective anthropometric indicator to identify insulin resistance. Objetivo: Verificar la prevalencia del síndrome metabólico y de la resistencia a la insulina en adolescentes obesos y su relación con distintos indicadores de composición corporal. Métodos: Estudio transversal con 79 adolescentes de 10 a 18 años. Los indicadores de composición corporal fueron: índice de masa corporal (IMC), porcentaje de grasa corporal, circunferencia abdominal y grasa subcutánea. El...
Source: Revista Paulista de Pediatria - March 28, 2014 Category: Pediatrics Source Type: research

Combining irbesartan and trichlormethiazide enhances blood pressure reduction via inhibition of sympathetic activity without adverse effects on metabolism in hypertensive rats with metabolic syndrome.
Abstract Abstract Sympathoexcitation and oxidative stress in the brain have pivotal roles in hypertension with metabolic syndrome (MetS). Here, we examined whether oral administration of irbesartan (IRB) and trichlormethiazide (TCM) decreases blood pressure (BP) via inhibiting sympathetic activity through anti-oxidant effects in the brain of spontaneously hypertensive rats (SHR-cp). IRB/TCM treatment decreased BP more profoundly than IRB monotherapy. Urinary norepinephrine excretion and oxidative stress in the brain were decreased in both IRB and IRB/TCM groups without any adverse effect on the metabolic profile. T...
Source: Clinical and Experimental Hypertension - March 28, 2014 Category: Cardiology Authors: Nishihara M, Hirooka Y, Sunagawa K Tags: Clin Exp Hypertens Source Type: research

Short-term intake of a Japanese-style healthy lunch menu contributes to prevention and/or improvement in metabolic syndrome among middle-aged men: a non-randomized controlled trial
Conclusions: This study presents new empirical data as a result of an original intervention program undertaken in Japan. A Japanese-style healthy lunch menu containing many vegetables consumed can help prevent and/or improve metabolic syndrome. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - March 27, 2014 Category: Lipidology Authors: Hiroko InoueRyosuke SasakiIzumi AisoToshiko Kuwano Source Type: research

The toxicity side‐effects of androgen deprivation therapy: the metabolic syndrome
Abstract In this series, the authors present cases of men being treated with androgen deprivation therapy, and highlight their management to prevent and treat associated toxicities. This fifth article will consider the management of the metabolic syndrome. Copyright © 2014 John Wiley & Sons (Source: Trends in Urology, Gynaecology and Sexual Health)
Source: Trends in Urology, Gynaecology and Sexual Health - March 27, 2014 Category: OBGYN Authors: Subhra Chowdhury, Lucy Dumas, Simon Chowdhury Tags: ADT Toxicity Source Type: research

Relationships of Hair Mineral Concentrations with Insulin Resistance in Metabolic Syndrome.
This study was conducted to investigate the relationship between hair mineral concentrations and insulin resistance in patients with metabolic syndrome (MS). A total of 456 subjects (161 patients with MS and 295 subjects without MS) were reviewed, and fasting plasma glucose, triglycerides, HDL-cholesterol, homeostasis assessment model-insulin resistance (HOMA-IR), and hair mineral concentrations were analyzed. While hair sodium and potassium concentrations were significantly higher, the hair calcium, magnesium, and zinc concentrations were lower in the MS group than in the control group. Regarding toxic element measurement...
Source: Biological Trace Element Research - March 27, 2014 Category: Biology Authors: Choi WS, Kim SH, Chung JH Tags: Biol Trace Elem Res Source Type: research

Prevalence and Correlates of Erectile Dysfunction in Type 2 Diabetes Mellitus: A Cross-Sectional Single-Center Study Among Turkish Patients
Metabolic Syndrome and Related Disorders , Vol. 0, No. 0. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - March 26, 2014 Category: Endocrinology Tags: article Source Type: research

Prevalence of metabolic syndrome and cardiovascular risk level in a vulnerable population
This study examined the prevalence of metabolic syndrome and the risk level of cardiovascular disease (CVD) in a vulnerable population of 407 subjects in Korea. This descriptive study was a part of the Tailed Health Visiting Service Program, using baseline data from public health centres in Suwon, Korea. The definition of metabolic syndrome was based on the National Cholesterol Education Program criteria, and risk of CVD was estimated according to the Framingham study equation. This study demonstrated that the prevalence of metabolic syndrome was 40.8% higher and the risk of CVD was significantly 3.1 times higher among tho...
Source: International Journal of Nursing Practice - March 26, 2014 Category: Nursing Authors: Chun‐Ja Kim, JeeWon Park, Se‐Won Kang Tags: Research Paper Source Type: research

Higher Rates and Clustering of Abnormal Lipids, Obesity, and Diabetes Mellitus in Psoriatic Arthritis Compared With Rheumatoid Arthritis
ConclusionCompared with RA, PsA is associated with higher rates of obesity, diabetes mellitus, and hypertriglyceridemia. (Source: Arthritis Care and Research)
Source: Arthritis Care and Research - March 26, 2014 Category: Rheumatology Authors: Monalyn Labitigan, Asena Bahče‐Altuntas, Joel M. Kremer, George Reed, Jeff D. Greenberg, Nicole Jordan, Chaim Putterman, Anna Broder Tags: Psoriatic Arthritis Source Type: research

Effect of the FTO rs9930506 polymorphism on obesity and the main clinical outcomes in patients with Psoriasis
This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - March 26, 2014 Category: Dermatology Authors: P. Coto‐Segura, L. González‐Lara, N. Eiris, J. Santos‐Juanes, R. Queiro, E. Coto Tags: Correspondence Source Type: research

Effect of the FTO rs9930506 polymorphism on obesity and the main clinical outcomes in patients with Psoriasis.
This article is protected by copyright. All rights reserved. PMID: 24673193 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 26, 2014 Category: Dermatology Authors: Coto-Segura P, González-Lara L, Eiris N, Santos-Juanes J, Queiro R, Coto E Tags: Br J Dermatol Source Type: research

Relationships between 24h free Urine Cortisol concentrations and Metabolic Syndrome in obese children.
Conclusions: Our findings support the hypothesis that changes in the HPA axis are related to the MetS in obesity. UFC seems to be a suitable marker for this relationship. Norm values for UFC adapted to obese children may help to avoid unnecessary dexamethasone suppression tests. PMID: 24670085 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - March 26, 2014 Category: Endocrinology Authors: Reinehr T, Kulle A, Wolters B, Knop C, Lass N, Welzel M, Holterhus PM Tags: J Clin Endocrinol Metab Source Type: research

Hydrogen Sulfide Upregulates Glutamate–Cysteine Ligase Catalytic Subunit, Glutamate–Cysteine Ligase Modifier Subunit, and Glutathione and Inhibits Interleukin-1β Secretion in Monocytes Exposed to High Glucose Levels
Metabolic Syndrome and Related Disorders , Vol. 0, No. 0. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - March 25, 2014 Category: Endocrinology Tags: article Source Type: research

Effect of treatment with methotrexate and coal tar on adipokine levels and indices of insulin resistance and sensitivity in patients with psoriasis vulgaris
ConclusionThe present results implicate that adipokines are significantly associated with pathogenesis of psoriasis and hence adequate and early control of psoriasis may contribute to the decreased development of metabolic syndrome, including the risk of cardiovascular disease. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - March 25, 2014 Category: Dermatology Authors: M. Rajappa, S. Rathika, M. Munisamy, L. Chandrashekar, D.M. Thappa Tags: Original Article Source Type: research

Fructose in obesity and cognitive decline: is it the fructose or the excess energy?
We read with interest the review by Lakhan and Kirchgessner, proposing that high fructose intake promotes obesity, metabolic syndrome, diabetes, and cognitive decline. Their focus on the role of fructose seems premature due to confounding from energy and the heavy reliance on low quality evidence from animal models. There is a lack of high quality evidence directly assessing the role of fructose in cognitive decline. Although one cannot exclude the possibility of a link, it remains an unconfirmed hypothesis. (Source: Nutrition Journal)
Source: Nutrition Journal - March 25, 2014 Category: Nutrition Authors: Laura ChiavaroliVanessa HaRussell de SouzaCyril KendallJohn Sievenpiper Source Type: research

Association between obesity and metabolic co-morbidities among children and adolescents in South Korea based on national data
Conclusions: Obesity was strongly associated with metabolic co-morbidities in South Korean children. (Source: BMC Public Health - Latest articles)
Source: BMC Public Health - Latest articles - March 25, 2014 Category: Consumer Health News Authors: Hyunjung LimHong XueYoufa Wang Source Type: research

Co-Inhibitory Suppression of T Cell Activation by CD40 Protects from Obesity and Adipose Tissue Inflammation in Mice.
CONCLUSIONS: We present the surprising finding that CD40 deficiency on T cells aggravates, while activation of CD40 signaling improves, adipose tissue inflammation and its metabolic complications. Positive modulation of the CD40 pathway might, therefore, describe a novel therapeutic concept against cardio-metabolic disease. PMID: 24664276 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - March 24, 2014 Category: Cardiology Authors: Wolf D, Jehle F, Anto Michel N, Bukosza EN, Rivera J, Chen YC, Hoppe N, Dufner B, Ortiz Rodriguez A, Colberg C, Nieto L, Rupprecht B, Wiedemann A, Schulte L, Peikert A, Bassler N, Lozhkin A, Hergeth SP, Stachon P, Hilgendorf I, Willecke F, von Zur Mühlen Tags: Circulation Source Type: research

Dietary sugar and body weight: have we reached a crisis in the epidemic of obesity and diabetes?: health be damned! Pour on the sugar.
Abstract Sugar-sweetened drinks have been associated with several health problems. In the point narrative as presented below, we provide our opinion and review of the data to date that we need to reconsider consumption of dietary sugar based on the growing concern of obesity and type 2 diabetes. In the counterpoint narrative following our contribution, Drs. Kahn and Sievenpiper provide a defense and suggest that dietary sugar is not the culprit. Data from the National Health and Nutrition Examination Survey and U.S. Department of Agriculture dietary surveys along with commercial Homescan data on household purchases...
Source: Diabetes Care - March 23, 2014 Category: Endocrinology Authors: Bray GA, Popkin BM Tags: Diabetes Care Source Type: research

Serum Leptin is Associated With Metabolic Syndrome in Obese Mexican Subjects
ConclusionThis study found that leptin was associated with the MetS, especially in obesity and insulin resistance, indicating a high risk for university workers to develop hypertension, DM2, and cardiovascular disease. (Source: Journal of Clinical Laboratory Analysis)
Source: Journal of Clinical Laboratory Analysis - March 22, 2014 Category: Laboratory Medicine Authors: Sara García‐Jiménez, German Bernal Fernández, Maria Fernanda Martínez Salazar, Antonio Monroy Noyola, Cairo Toledano Jaimes, Angelica Meneses Acosta, Leticia Gonzalez Maya, Elizabeth Aveleyra Ojeda, Maria A. Terrazas Meraz, Boll Marie‐Catherine, M Tags: Research Article Source Type: research

Resistin regulates the expression of plasminogen activator inhibitor-1 in 3T3-L1 adipocytes.
In this study, to clarify the relationship between expression of resistin and PAI-1, PAI-1 expression in differentiated 3T3-L1 adipocytes was measured after transfection with anti-resistin siRNA. We found that PAI-1 gene expression and secreted PAI-1 protein were significantly decreased by resistin knockdown. Furthermore, phosphorylation of Akt, which can inhibit PAI-1 expression, was accelerated and the activity of protein phosphatase 2A (PP2A) was suppressed in resistin knockdown 3T3-L1 adipocytes. In addition, the expression of glucose transporter type 4, a ChREBP target gene, was reduced and was associated with inhibit...
Source: Biochemical and Biophysical Research communications - March 22, 2014 Category: Biochemistry Authors: Ikeda Y, Tsuchiya H, Hama S, Kajimoto K, Kogure K Tags: Biochem Biophys Res Commun Source Type: research

Cystatin C, CRP, log TG/HDLc and metabolic syndrome are associated with microalbuminuria in hypertension
Conclusion: CysC, CRP, log TG/HDLc, and the presence of three or more criteria for metabolic syndrome, regardless of serum creatinine, were associated with microalbuminuria, an early marker of kidney damage and cardiovascular risk in patients with essential hypertension. (Source: Arquivos Brasileiros de Cardiologia)
Source: Arquivos Brasileiros de Cardiologia - March 21, 2014 Category: Cardiology Source Type: research

Relation of Acanthosis Nigricans to Metabolic Syndrome in Overweight and Obese Women
Metabolic Syndrome and Related Disorders , Vol. 0, No. 0. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - March 21, 2014 Category: Endocrinology Tags: article Source Type: research

Diagnostic values of different definitions of metabolic syndrome to detect poor health status in Iranian adults without diabetes
ConclusionThere was no difference in the four different definitions of the metabolic syndrome in detecting poor health status among Iranian adults.This article is protected by copyright. All rights reserved. (Source: Diabetic Medicine)
Source: Diabetic Medicine - March 21, 2014 Category: Endocrinology Authors: P. Amiri, T. Deihim, F. Hosseinpanah, M. Barzin, M. Hasheminia, A. Montazeri, F Azizi Tags: Research Article Source Type: research

Humanized animal exercise model for clinical implication.
Abstract Exercise and physical activity function as a patho-physiological process that can prevent, manage, and regulate numerous chronic conditions, including metabolic syndrome and age-related sarcopenia. Because of research ethics and technical difficulties in humans, exercise models using animals are requisite for the future development of exercise mimetics to treat such abnormalities. Moreover, the beneficial or adverse outcomes of a new regime or exercise intervention in the treatment of a specific condition should be tested prior to implementation in a clinical setting. In rodents, treadmill running (or swim...
Source: Pflugers Archiv : European Journal of Physiology - March 21, 2014 Category: Physiology Authors: Seo DY, Lee SR, Kim N, Ko KS, Rhee BD, Han J Tags: Pflugers Arch Source Type: research

Interaction between hepatitis C virus and metabolic factors.
Abstract Hepatitis C virus (HCV) infection disrupts the normal metabolism processes, but is also influenced by several of the host's metabolic factors. An obvious and significantly detrimental pathophysiological feature of HCV infection is insulin resistance in hepatic and peripheral tissues. Substantial research efforts have been put forth recently to elucidate the molecular mechanism of HCV-induced insulin resistance, and several cytokines, such as tumor necrosis factor-α, have been identified as important contributors to the development of insulin resistance in the distant peripheral tissues of HCV-infected pat...
Source: World Journal of Gastroenterology : WJG - March 21, 2014 Category: Gastroenterology Authors: Kawaguchi Y, Mizuta T Tags: World J Gastroenterol Source Type: research

Arterial stiffness and influences of the metabolic syndrome: A cross-countries study
In conclusion, different component clusters of MetS showed varying associations with arterial stiffness (PWV).Highlights: (Source: Atherosclerosis)
Source: Atherosclerosis - March 20, 2014 Category: Cardiology Authors: Angelo Scuteri, Pedro G. Cunha, Enrico Agabiti Rosei, Jolita Badariere, Sofie Bekaert, John R. Cockcroft, Jorge Cotter, Francesco Cucca, Marc L. De Buyzere, Tim De Meyer, Luigi Ferrucci, Osca Franco, Nichols Gale, Thierry C. Gillebert, Michel Langlois, Al Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research

High hexacosanoic acid levels are associated with coronary artery disease
Conclusion: High C26:0 levels in whole blood may be an independent marker for identifying the risks of CAD.Highlights: (Source: Atherosclerosis)
Source: Atherosclerosis - March 20, 2014 Category: Cardiology Authors: Tetsuro Miyazaki, Kazunori Shimada, Makoto Hiki, Atsumi Kume, Yohei Kitamura, Kyoichi Oshida, Naotake Yanagisawa, Takashi Kiyanagi, Rie Matsumori, Hiroyuki Daida Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research

Modulation of adiponectin as a potential therapeutic strategy
Abstract: Adiponectin is produced predominantly by adipocytes and plays an important role in metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti-inflammatory and anti-atherogenic properties. Recently, it has been observed that lower levels of adiponectin can substantially increase the risk of developing type 2 diabetes, metabolic syndrome, atherosclerosis, and cardiovascular disease in patients who are obese. Circulating adiponectin levels are inversely related to the inflammatory process, oxidative stress, and metabolic dysregulation. Intensive lifestyle modifications and pharmacologi...
Source: Atherosclerosis - March 20, 2014 Category: Cardiology Authors: Soo Lim, Michael J. Quon, Kwang Kon Koh Tags: Reviews Source Type: research

New and emerging regulators of intestinal lipoprotein secretion
Abstract: Overproduction of hepatic apoB100-containing VLDL particles has been well documented in animal models and in humans with insulin resistance such as the metabolic syndrome and type 2 diabetes, and contributes to the typical dyslipidemia of these conditions. In addition, postprandial hyperlipidemia and elevated plasma concentrations of intestinal apoB48-containing chylomicron and chylomicron remnant particles have been demonstrated in insulin resistant states. Intestinal lipoprotein production is primarily determined by the amount of fat ingested and absorbed. Until approximately 10 years ago, however, relatively l...
Source: Atherosclerosis - March 20, 2014 Category: Cardiology Authors: Changting Xiao, Satya Dash, Cecilia Morgantini, Gary F. Lewis Tags: Reviews Source Type: research

Neural control of blood flow during exercise in human metabolic syndrome
Conclusion. Adults with MetSyn exhibit greater resting MSNA and clonidine‐mediated vasoconstriction, yet preserved functional sympatholysis and higher exercise blood flow during low‐intensity handgrip exercise when compared with age‐matched healthy controls. These results suggest adults with MetSyn exhibit compensatory vascular control mechanisms capable of preserving blood flow responses to exercise in the face of augmented sympathetic adrenergic activity. This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - March 20, 2014 Category: Physiology Authors: Jacqueline K. Limberg, Barbara J. Morgan, Joshua J. Sebranek, Lester T. Proctor, Marlowe W. Eldridge, William G. Schrage Tags: Research Paper Source Type: research

Steroid Sulfatase Alleviates Type 2 Diabetes [Molecular Bases of Disease]
In this report, we first showed that the liver expression of Sts was induced in both the high fat diet (HFD) and ob/ob models of obesity and type 2 diabetes and during the fed to fasting transition. In defining the functional relevance of STS induction in metabolic disease, we showed that overexpression of STS in the liver of transgenic mice alleviated HFD and ob/ob models of obesity and type 2 diabetes, including reduced body weight, improved insulin sensitivity, and decreased hepatic steatosis and inflammation. Interestingly, STS exerted its metabolic benefit through sex-specific mechanisms. In female mice, STS may have ...
Source: Journal of Biological Chemistry - March 20, 2014 Category: Chemistry Authors: Jiang, M., He, J., Kucera, H., Gaikwad, N. W., Zhang, B., Xu, M., O'Doherty, R. M., Selcer, K. W., Xie, W. Tags: Metabolism Source Type: research

Metabolic Syndrome as a Predictor for Postoperative Complications After Urologic Surgery
(Source: Urology)
Source: Urology - March 20, 2014 Category: Urology & Nephrology Authors: J.Patrick Selph, William M. Whited, Angela B. Smith, Jonathan Matthews, Raj S. Pruthi, Eric M. Wallen, Matthew E. Nielsen, Michael E. Woods Source Type: research