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Association of Serum Uric Acid With Cardiometabolic Risk Factors and Metabolic Syndrome in Iranian Adolescents: the CASPIAN-III Study.
CONCLUSIONS: Our study showed that those adolescents with metabolic syndrome had higher SUA levels. Its association with some components of metabolic syndrome supports that SUA might be an additional component of metabolic syndrome even during adolescence. PMID: 27225720 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - May 28, 2016 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Determinants for gallstone formation - a new data cohort study and a systematic review with meta-analysis.
CONCLUSIONS: Age, female sex, BMI, non-HDL cholesterol, and polyps are independent determinants for gallstone formation. Incident gallstones and the metabolic syndrome share common risk factors. More studies are needed for further exploration. PMID: 27232657 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - May 28, 2016 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Treating young adults with Type 2 Diabetes or Monogenic Diabetes
Publication date: Available online 27 May 2016 Source:Best Practice & Research Clinical Endocrinology & Metabolism Author(s): Katharine R. Owen It is increasingly recognised that diabetes in young adults has a wide differential diagnosis. There are many monogenic causes, including monogenic beta-cell dysfunction, mitochondrial diabetes and severe insulin resistance. Type 2 diabetes in the young is becoming more prevalent, particularly after adolescence. It’s important to understand the clinical features and diagnostic tools available to classify the different forms of young adult diabetes. Classic type...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - May 28, 2016 Category: Endocrinology Source Type: research

The association between long working hours and metabolic syndrome remains elusive
(Source: The European Journal of Public Health)
Source: The European Journal of Public Health - May 28, 2016 Category: Journals (General) Authors: Pimenta, A. M., Martinez-Gonzalez, M. A. Tags: Letter to the Editor Source Type: research

IJERPH, Vol. 13, Pages 544: BMI and BMD: The Potential Interplay between Obesity and Bone Fragility
Recent evidence demonstrating an increased fracture risk among obese individuals suggests that adipose tissue may negatively impact bone health, challenging the traditional paradigm of fat mass playing a protective role towards bone health. White adipose tissue, far from being a mere energy depot, is a dynamic tissue actively implicated in metabolic reactions, and in fact secretes several hormones called adipokines and inflammatory factors that may in turn promote bone resorption. More specifically, Visceral Adipose Tissue (VAT) may potentially prove detrimental. It is widely acknowledged that obesity is positively associa...
Source: International Journal of Environmental Research and Public Health - May 28, 2016 Category: Environmental Health Authors: Andrea PalermoDario TuccinardiGiuseppe DefeudisMikiko WatanabeLuca D’OnofrioAngelo Lauria PantanoNicola NapoliPaolo PozzilliSilvia Manfrini Tags: Review Source Type: research

Short-term antidiabetic treatment with insulin or metformin has a similar impact on the components of metabolic syndrome in women with gestational diabetes mellitus requiring antidiabetic agents: results of a prospective, randomised study.
In conclusion, short-term antidiabetic treatment with insulin or metformin has a similar impact on markers of metabolic syndrome in women with GDM requiring antidiabetic treatment. Secondly, treatment with metformin is associated with increased triglyceride levels and higher AIP in the third trimester in pregnant women with GDM. PMID: 27226182 [PubMed - in process] (Source: Journal of Physiology and Pharmacology)
Source: Journal of Physiology and Pharmacology - May 27, 2016 Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research

Assessment of incretins in oral glucose and lipid tolerance tests may be indicative in the diagnosis of metabolic syndrome aggravation.
Authors: Kiec-Klimczak M, Malczewska-Malec M, Razny U, Zdzienicka A, Gruca A, Goralska J, Pach D, Gilis-Januszewska A, Dembinska-Kiec A, Hubalewska-Dydejczyk A Abstract Incretins stimulated by oral meals are claimed to be protective for the pancreatic beta cells, to increase insulin secretion, to inhibit glucagon release, slow gastric emptying (glucagon-like peptide-1) and suppress appetite. Recently it has however been suggested that glucagon-like peptide-1 (GLP-1) is putative early biomarker of metabolic consequences of the obesity associated proinflammatory state. The study was aimed to compare the release of in...
Source: Journal of Physiology and Pharmacology - May 27, 2016 Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research

PS300 Depression in the Metabolic Syndrome and its Association with Inflamation
The metabolic syndrome and the cardiovascular disease have a common pathophysiologic mechanism, a low grade inflammation mediated by inflammatory cytokines (Interleukin-6 (IL-6), Tumor necrosis factor and C – reactive protein (CRP)) which produce insulin resistance that is responsible of the metabolic syndrome. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: B.S. Cruz Romero Tags: Poster Abstract Source Type: research

PS144 Prevalence of Metabolic Syndrome in Acute Coronary Syndrome in Nepalese Population
Metabolic Syndrome (MetS) is rapidly increasing in prevalence worldwide as a consequence of the global epidemics of obesity and sedentary lifestyles. Presence of MetS increases the risk of Cardiovascular Disease (CVD) twice in next 5 to 10 years. In health care services the value of MetS derives largely from its potential to reduce the risk of CVD in the general population by treating the disease. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: P. Karki, J. Lamsal, M. Lamsal Tags: Poster Abstract Source Type: research

PS073 Hypertriglyceridemia Effect on Arterial Function Parameters in Middle Aged Patients with Metabolic Syndrome
Hypertriglyceridemia is a common lipid disorder associated with an increased risk of heart disease. It is unclear whether metabolic syndrome and hypertriglyceridemia are true causal cardiovascular risk factors that can be modified with treatment or are merely biomarkers of future risk. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: E. Rinkūnienė, A. Jucevičienė, V. Dženkevičiūtė, Ž. Petrulionienė, R. Puronaitė, G. Bieliauskaitė, A. Laucevičius, S. Kutkienė Tags: Poster Abstract Source Type: research

PS046 High Lymphocytes and Low Mean Corpuscular Volume are Associated with Diabetes, Triglyceride-to-High-Density Lipoprotein Ratio and Metabolic Syndrome, in Patients at High Risk of Coronary Artery Disease
The platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR) and other CBC parameters are easily attainable markers of inflammation which have been suggested for risk stratification in ACS and CAD. However, little is known of the association of these parameters with diabetes (DM), the TG/HDL-C ratio, lipids and the metabolic syndrome (MetS). (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: B.V. Li, I. Trakarnwijitr, H. Adams, J. Layland, J. Garlick, A. Wilson Tags: Poster Abstract Source Type: research

PM308 Metaboreflex Activation by Rhythmic Exercise as a Cardiovascular Risk in Metabolic Syndrome and Obesity
The increasing prevalence of metabolic syndrome (MS) worldwide seems to be driven largely by obesity exacerbated by sedentary lifestyle. Some dysregulation in a mechanism causing cardiovascular, and hemodynamic adjustments during exercise (Metaboreflex; a feed-back mechanism originating in skeletal muscle due to local metabolites) has been studied in detail in MS. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: M. Bajpai, P. Dubey, S. Khattri Tags: Poster Abstract Source Type: research

PM091 Structural Changes in the Left Ventricle Induced by High Sucrose Ingestion in Rats. Partial Prevention or Reversal by Exercise
Excessive consumption of sucrose has damaging effects upon health. Metabolic syndrome (MetS) can be induced by the ingestion of high concentrations of sucrose. The risk of cardiovascular (CV) morbidity and mortality increases three-fold in patients with MetS due, in part, to left ventricular (LV) dysfunction. However, to what extent LV function is impaired in MetS is controversial and the damage caused by a high sucrose intake upon the LV, has not been described. Aerobic physical training at moderate intensity, acting as a non-pharmacological treatment, might effectively mitigate both, the appearance and the reversal of so...
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: V. Guarner-Lans, M. Martínez-Rosas, J. Vargas-Barrón, P. Flores, J. Villegas Tags: Poster Abstract Source Type: research

PM079 Postmenopausal Metabolic Syndrome and Vascular Characteristics: Influence of Hypoglycemic Drugs
Metabolic syndrome (MS) in postmenopausal women is a common state with high risk of diabetes mellitus and cardiovascular morbility and mortality. The importance of correction of dyslipidemia, glycemic and blood pressure control in these subjects is obvious. The most interesting topic of these interventions is the ability of hypoglycemic drugs (HD) to influence the characteristics of MS and vascular characteristics (VC). (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: O.A. Kislyak, A.V. Starodubova, J.B. Chervjakova, A.A. Kopelev Tags: Poster Abstract Source Type: research

PM073 Gender Features of Myocardial Electrical Instability in Patients With Arterial Hypertension and Metabolic Syndrome
The purpose - analysis of myocardial electrical instability in patients with metabolic syndrome (MS) and arterial hypertension (AH). (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: B.G. Hodjakuliyev, B.N. Orayeva, M.B. Muhammedov Tags: Poster Abstract Source Type: research

PT317 The Altered Activity of Serum MMP 9 may act as Diagnostic Biomarker for Cardiovascular Events in Metabolic Syndrome
These Matrix enzymes believed to play a role in tissue remodelling and repair. Excessive or impaired expression of MMPs may contribute to the pathogenesis of many disorders like metabolic disorders, cardiovascular diseases and tumor progression. MMPs are found to be highly expressed in various tissues like atherosclerotic plaques, synovium, glomerulus which may further leads to complex diseases. The web of metabolic disorders leads to metabolic syndrome which is associated with high risk of diabetes. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: S. Khattri, S.S. Yadav, M. Bajpai, S. Shukla, K.K. Pant Tags: Poster Abstract Source Type: research

PT130 Analysis of the Causes of Destabilization of Coronary Heart Disease Within 1 Year, Depending on the Presence or Absence of Metabolic Syndrome
Despite the significant achievements of cardiotreatment, CHD continues to be a very relevant problem. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: G. Nagaeva, S. Nagaev, N. Yuldashev, R. Mamutov Tags: Poster Abstract Source Type: research

Metabolic syndrome and osteoporotic fracture: a population-based study in China
The objective of the study was to determine whether metabol... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - May 27, 2016 Category: Endocrinology Authors: Li Qin, Zhen Yang, Weiwei Zhang, Hongxia Gu, Xiaoyong Li, Lingfei Zhu, Shuai Lu, Yin Xing, Hongmei Zhang, Yixin Niu, Guang Ning and Qing Su Source Type: research

Metabolic syndrome is associated with disease activity in patients with rheumatoid arthritis
Conclusion Remission rate is significantly lower in RA patients with MS. Disease activity of RA, body mass index, and educational level are associated with metabolic syndrome in patients with RA. (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 27, 2016 Category: Orthopaedics Source Type: research

The Electronic CardioMetabolic Program (eCMP) for Patients With Cardiometabolic Risk: A Randomized Controlled Trial
Conclusions: The technology-assisted eCMP is a feasible and well-accepted intervention and may significantly decrease cardiometabolic risk among high-risk individuals. Trial Registration: Clinicaltrials.gov NCT02246400; https://clinicaltrials.gov/ct2/show/NCT02246400 (Archived by WebCite at http://www.webcitation.org/6h6mWWokP) (Source: Journal of Medical Internet Research)
Source: Journal of Medical Internet Research - May 27, 2016 Category: Journals (General) Authors: Kristen MJ AzarSuneil KoliwadTak PoonLan XiaoNan LvRobert GriggsJun Ma Source Type: research

Contribution of Cyclooxygenase End Products and Oxidative Stress to Intrahepatic Endothelial Dysfunction in Early Non-Alcoholic Fatty Liver Disease
Conclusions Our study provides evidence that endothelial dysfunction at an early stage of NAFLD is associated with reduced NO bioavailability together with increased cyclooxygenase end products and oxidative stress, which suggests that both pathways are involved in the pathophysiology and may be worth exploring as therapeutic targets to prevent progression of the disease. (Source: PLoS One)
Source: PLoS One - May 26, 2016 Category: Biomedical Science Authors: Francisco Javier Gonzalez-Paredes Source Type: research

Effect and Mechanism of Virechana Karma (Therapeutic Purgation) Over Fructose-Induced Metabolic Syndrome: An Experimental Study
Conclusion. Experimental evaluation showed decrease in fatty acid in the storage like liver, kidney, heart, and muscle adipose tissue can indirectly increase the insulin sensitivity in insulin receptor present at skeletal muscles. (Source: Complementary Health Practice Review)
Source: Complementary Health Practice Review - May 26, 2016 Category: Complementary Medicine Authors: Chaturvedi, A., Rao, P. N., Kumar, M. A., Ravishankar, B., Rao, N., Ravi, M. Tags: Original Articles Source Type: research

The Individual, Joint, and Additive Interaction Associations of Aerobic-Based Physical Activity and Muscle Strengthening Activities on Metabolic Syndrome
Conclusion In this national sample, accelerometer-assessed physical activity and muscle strengthening activities were synergistically associated with metabolic syndrome. (Source: International Journal of Behavioral Medicine)
Source: International Journal of Behavioral Medicine - May 26, 2016 Category: Psychiatry Source Type: research

Cardiovascular Disease Risk is Only Elevated in Hypertensive, Formerly Preeclamptic Women
(BJOG. 2015;122(8):1092–1100) Preeclampsia (PE) complicates 5% to 8% of all pregnancies and is associated with an increased risk for premature cardiovascular disease (CVD) later in life. Patients with a history of PE have a 2-fold to 7-fold risk of developing ischemic cardiac disease compared with healthy controls, depending on gestational age at delivery, and about a 4-fold risk of developing chronic hypertension within 15 years after pregnancy. Although it is unknown whether PE itself increases the risk of CVD independently or through risk factors associated with both PE and CVD, patients with a history of PE tend to ...
Source: Obstetric Anesthesia Digest - May 25, 2016 Category: Anesthesiology Tags: Mother, Fetus, Neonate Source Type: research

Herpes zoster ophthalmicus and varicella zoster virus vasculopathy
ABSTRACT Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopat...
Source: Arquivos Brasileiros de Oftalmologia - May 25, 2016 Category: Opthalmology Source Type: research

Comment on: "measurement and clinical implications of choroidal thickness in patients with inflammatory bowel disease"
ABSTRACT Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopat...
Source: Arquivos Brasileiros de Oftalmologia - May 25, 2016 Category: Opthalmology Source Type: research

Evaluation of a simulation tool in ophthalmology: application in teaching funduscopy
ABSTRACT Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopat...
Source: Arquivos Brasileiros de Oftalmologia - May 25, 2016 Category: Opthalmology Source Type: research

Acquired restrictive strabismus in infancy associated with neurofibromatosis type 2
ABSTRACT Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopat...
Source: Arquivos Brasileiros de Oftalmologia - May 25, 2016 Category: Opthalmology Source Type: research

Study of the relationship between male erectile dysfunction and type 2 diabetes mellitus/metabolic syndrome and its components
Conclusion These current findings suggest that the MetS and its components have a negative impact on male erectile function. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 25, 2016 Category: Research Authors: Chaudhary, R. K., Shamsi, B. H., Tan, T., Chen, H.-M., Xing, J.-P. Tags: Clinical Note Source Type: research

Home-based lifestyle intervention for rural adults improves metabolic syndrome parameters and cardiovascular risk factors: A randomised controlled trial
This study evaluated the effectiveness of a 6-month home-based physical activity and diet intervention for rural adults with, or at risk of MetS. The randomised controlled trial was conducted in Albany and surrounding towns, Western Australia, 2014–2015. Participants were screened for MetS using the International Diabetes Federation criteria, and eligible participants were randomly assigned to the intervention (n=201) or control (n=200) group. The intervention group received printed and online programme materials and motivational support, and the control group was waitlisted to receive the programme after post-test data ...
Source: Preventive Medicine - May 25, 2016 Category: Global & Universal Source Type: research

Comparison of the fecal microbiota in horses with Equine Metabolic Syndrome (EMS) and metabolically normal controls fed a similar all forage diet
Equine Metabolic Syndrome (EMS) is an ever increasing problem in the equine industry, especially considering that it is a risk factor for the development of laminitis. EMS is similar to metabolic syndrome in humans, which has been associated with alterations in intestinal microbiota. However, no work to date has been published to characterize the fecal microbiota in the EMS horse to determine differences, if any, from the metabolically normal animal. Therefore our objective was to characterize the fecal microbiota of horses with EMS compared to non-EMS controls. (Source: Journal of Equine Veterinary Science)
Source: Journal of Equine Veterinary Science - May 25, 2016 Category: Veterinary Research Authors: S. Elzinga, J.S. Weese, A.A. Adams Tags: Original Research Source Type: research

An observational study to examine changes in metabolic syndrome components in patients with breast cancer receiving neoadjuvant or adjuvant chemotherapy
CONCLUSIONSA 12‐week to 18‐week course of chemotherapy appears to statistically significantly increase MetS and related anthropometrics, biomarkers of glucose metabolism, and inflammation in patients with early‐stage breast cancer with no preexisting MetS. Lifestyle interventions such as diet and exercise may be preventive approaches for use during chemotherapy to reduce the onset of MetS in patients with breast cancer. Cancer 2016. © 2016 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. (Source: Cancer)
Source: Cancer - May 24, 2016 Category: Cancer & Oncology Authors: Christina M. Dieli‐Conwright, Louise Wong, Sarah Waliany, Leslie Bernstein, Behrouz Salehian, Joanne E. Mortimer Tags: Original Article Source Type: research

Inter-relationships between the severity of metabolic syndrome, insulin and adiponectin and their relationship to future type 2 diabetes and cardiovascular disease
p; J G Woo (Source: International Journal of Obesity)
Source: International Journal of Obesity - May 24, 2016 Category: Eating Disorders and Weight Management Authors: M D DeBoerM J GurkaJ A MorrisonJ G Woo Source Type: research

Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance
Fructose may be a key contributor to the biochemical alterations which promote the metabolic syndrome (MetS), non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2DM): a) its consumption in all forms but especially in liquid form has much increased alongside with incidence of MetS conditions; b) it is metabolized almost exclusively in the liver, where it stimulates de novo lipogenesis to drive hepatic triglyceride (TG) synthesis which c) contributes to hepatic insulin resistance and NAFLD [1–6]. (Source: Medical Hypotheses)
Source: Medical Hypotheses - May 24, 2016 Category: Biomedical Science Authors: Alejandro Gugliucci Source Type: research

Effects of postnatal bromocriptine injection on thyroid function and prolactinemia of rats at adulthood
Previously, we demonstrated that maternal prolactin inhibition at the end of lactation, using bromocriptine (BRO), leads to an increase in leptin transfer via milk and induces the adult progeny to present hypothyroidism, leptin resistance and metabolic syndrome (obesity, hyperglycemia, hypertriglyceridemia, lower HDL). To test if these alterations are due to direct BRO action on the pups, in the present study we evaluated the long-term effects of direct injection of BRO (0.1μg/once daily) in male Wistar rats from postnatal (PN) day 1 to 10 (early treatment) or from PN11 to 20 (late treatment) on: food intake, body mass, c...
Source: Neuropeptides - May 24, 2016 Category: Neuroscience Authors: Janaine C. Carvalho, Patricia C. Lisboa, Elaine de Oliveira, Nayara Peixoto-Silva, Jessica L. Nobre, Mabel C. Fraga, Alex C. Manhães, Egberto G. Moura Source Type: research

Association of K121Q Polymorphism in Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 with Clinical Characteristics of Metabolic Syndrom
Conclusion: The K121Q polymorphism of ENPP1 showed no direct correlation with MS, although it showed some correlation with BMI and WC in MS patients.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - May 24, 2016 Category: Endocrinology Authors: Li, N.Pan, H.Cui, M.Li, Q. Tags: Article Source Type: research

Are Obese Individuals with no Feature of Metabolic Syndrome but Increased Waist Circumference Really Healthy? A Cross Sectional Study
Conclusion: Our data do not support the characterization of metabolically healthy obesity, even definite, as really healthy, as many patients with this phenotype have abnormal cardiovascular markers and glucose or liver abnormalities. HbA1c measurement seems to be more sensitive than OGTT to detect dysglycemia in this population.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - May 24, 2016 Category: Endocrinology Authors: Chiheb, S.Cosson, E.Banu, I.Hamo-Tchatchouang, E.Cussac-Pillegand, C.Nguyen, M. T.Valensi, P. Tags: Article Source Type: research

Cumulative Risk of Metabolic Syndrome Correlated with the Coexistence of (-1306C/T) and Altered Circulating MMP2 level
Conclusion: Our study concluded that presence of MMP-2 (-1306 C/T) might be associated the risk of MetS. Serum MMP2 level was significantly higher in patients and correlated with clinical parameters of MetS. Clinical implication of the work may help to identify the individuals with high risk of MetS and further complications.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - May 24, 2016 Category: Endocrinology Authors: Yadav, S. S.Mandal, R. K.Singh, M. K.Dwivedi, P.Sethi, R.Usman, K.Khattri, S. Tags: Article Source Type: research

Lymphatic pumping: Mechanics, mechanisms and malfunction.
This article is protected by copyright. All rights reserved. PMID: 27219461 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - May 24, 2016 Category: Physiology Authors: Scallan JP, Zawieja SD, Castorena-Gonzalez JA, Davis MJ Tags: J Physiol Source Type: research

MiR-206 is Expressed in Pancreatic Islets and Regulates Glucokinase Activity.
In this study, we investigated the role of miR-206 as a post-transcriptional regulator of Gck. In addition, we examined the effects of miR-206 on glucose tolerance, GSIS, and gene expression in control and germ line miR-206 knock-out (KO) mice fed either with chow or high-fat diet (HFD). MiR-206 was found in Gck-expressing tissues and was differentially altered in response to HFD-feeding. Pancreatic islets showed the most profound induction in the expression of miR-206 in response to HFD. Chow- and HFD-fed miR-206 KO mice have improved glucose tolerance and GSIS but unaltered insulin sensitivity. In silico analysis of Gck ...
Source: American Journal of Physiology. Endocrinology and Metabolism - May 24, 2016 Category: Physiology Authors: Vinod M, Patankar JV, Sachdev V, Frank S, Graier WF, Kratky D, Kostner GM Tags: Am J Physiol Endocrinol Metab Source Type: research

Male sex may be associated with higher metabolic risk in first-episode schizophrenia patients: A preliminary study.
CONCLUSION: These preliminary results suggest that male FEP patients may be more predisposed to insulin resistance and dyslipidemia than female FEP patients. These results could contribute to the understanding of prevention and treatment of metabolic syndrome in FEP patients. PMID: 27208452 [PubMed - as supplied by publisher] (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - May 23, 2016 Category: Psychiatry Tags: Asian J Psychiatr Source Type: research

Examining the association between serum lactic dehydrogenase and all-cause mortality in patients with metabolic syndrome: a retrospective observational study
Conclusions Results support a positive association between higher level of serum LDH and mortality from all causes in individuals with MetS. (Source: BMJ Open)
Source: BMJ Open - May 23, 2016 Category: Journals (General) Authors: Wu, L.-W., Kao, T.-W., Lin, C.-M., Yang, H.-F., Sun, Y.-S., Liaw, F.-Y., Wang, C.-C., Peng, T.-C., Chen, W.-L. Tags: Open access, Epidemiology, Global health, Public health Research Source Type: research

Effect of Metabolic Syndrome and Obesity on Complications After Shoulder Arthroplasty.
This study evaluated the postoperative outcomes of patients with metabolic syndrome after total shoulder arthroplasty (TSA). A retrospective cohort study of 4751 patients undergoing TSA was conducted with use of the American College of Surgeons National Surgical Quality Improvement Program database from 2005 to 2013. Metabolic syndrome was defined as hypertension, diabetes, and body mass index of 30.0 kg/m(2) or greater. Multivariable logistic regression analysis was performed for the outcomes of any postoperative complications and extended length of stay. Patients classified as obese III had a significantly increased risk...
Source: Orthopedics - May 23, 2016 Category: Orthopaedics Authors: Garcia GH, Fu MC, Webb ML, Dines DM, Craig EV, Gulotta LV Tags: Orthopedics Source Type: research

Synergistic effect of vitamin D and low concentration of transforming growth factor beta 1, a potential role in dermal wound healing
Vitamin D, particularly its most active metabolite 1,25(OH)2D3, has effects on a wide range of physiological processes [1]. Vitamin D is known to be important in many aspects of biology, including calcium, phosphorus, and bone metabolism, muscle strength, immune homeostasis, and other functions in tissues expressing vitamin D receptors [2,3]. Vitamin D deficiency increases the risk for many pathological conditions, such as poor bone metabolism, chronic liver and kidney diseases, infectious diseases, cancer, metabolic syndrome, autoimmune disorders [3–7,1,8], and fibrosis including liver fibrosis, cystic fibrosis, systemi...
Source: Burns : Journal of the International Society for Burn Injuries - May 22, 2016 Category: Cosmetic Surgery Authors: Jie Ding, Peter Kwan, Zengshuan Ma, Takashi Iwashina, Jianfei Wang, Heather A. Shankowsky, Edward E. Tredget Source Type: research

Parity, duration of lactation and prevalence of maternal metabolic syndrome: a cross-sectional study
Conclusions Our data did not support protective roles of lactation in development of metabolic syndrome, since in our study longer lactation durations as well as higher number of parities were seen among participants with metabolic syndrome. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - May 22, 2016 Category: OBGYN Source Type: research

Metabolic Syndrome in Children and Adolescents Living with HIV
The objective of this study is to assess the prevalence and characteristics of MetS in HIV-infected children and adolescents in Spain. Methods: A cross-sectional multicenter study in 152 patients from the pediatric cohort of the Spanish AIDS Research Network (CoRISpe) was performed. MetS was defined according to the new International Diabetes Federation (IDF) diagnostic criteria and the modified National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) criteria. Measurements included anthropometry, waist circumference, blood pressure, fasting lipids, glucose and insulin and lipodystrophy assessment. ...
Source: The Pediatric Infectious Disease Journal - May 21, 2016 Category: Infectious Diseases Tags: HIV Reports Source Type: research

An observational study of sequential protein-sparing, very low-calorie ketogenic diet (Oloproteic diet) and hypocaloric Mediterranean-like diet for the treatment of obesity.
Authors: Castaldo G, Monaco L, Castaldo L, Galdo G, Cereda E Abstract The impact of a rehabilitative multi-step dietary program consisting in different diets has been scantily investigated. In an open-label study, 73 obese patients underwent a two-phase weight loss (WL) program: a 3-week protein-sparing, very low-calorie, ketogenic diet (<500 kcal/day; Oloproteic(®) Diet) and a 6-week hypocaloric (25-30 kcal/kg of ideal body weight/day), low glycemic index, Mediterranean-like diet (hypo-MD). Both phases improved visceral adiposity, liver enzymes, GH levels, blood pressure and glucose and lipid metabolism. H...
Source: International Journal of Food Sciences and Nutrition - May 21, 2016 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research

Menopause status is associated with circadian- and sleep-related alterations
Objective: The aim of the study was to investigate whether postmenopausal women show differences in circadian-related variables and sleep characteristics compared with premenopausal women, and to analyze potential associations between these circadian-related variables and abdominal fat distribution or metabolic syndrome (MetS) components. Methods: A total of 177 women were studied (127 premenopausal, 50 postmenopausal). Sixty percent of the total population was overweight/obese, with no significant differences between premenopausal (60%) and postmenopausal women (62%) (P = 0.865). Wrist temperature (WT) and rest-activ...
Source: Menopause - May 21, 2016 Category: OBGYN Tags: Original Articles Source Type: research

International Variability in Diet and Requirements of Manganese: Causes and Consequences
Publication date: Available online 20 May 2016 Source:Journal of Trace Elements in Medicine and Biology Author(s): Jean H. Freeland-Graves, Tamara Y. Mousa, Sangyoung Kim Manganese (Mn) is an essential trace element that is critical for human health and development. At the turn of the century when diets were based on whole grains, cereals and other traditional foods, Mn intakes (8–9mg/d) were much greater than that prevalent today (2mg/d). As societies have developed, diets have shifted as part of a nutrition transition, to those that are high in processed foods, fat, and sugar. These foods are virtually devoid of M...
Source: Journal of Trace Elements in Medicine and Biology - May 21, 2016 Category: Biochemistry Source Type: research

Aging and inflammation in patients with HIV infection
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Immunology)
Source: Clinical and Experimental Immunology - May 20, 2016 Category: Allergy & Immunology Authors: M. Nasi, S. De Biasi, L. Gibellini, E. Bianchini, S. Pecorini, V. Bacca, G. Guaraldi, C. Mussini, M. Pinti, A. Cossarizza Tags: Review Source Type: research