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Parathyroid gland angiography with indocyanine green fluorescence to predict parathyroid function after thyroid surgery
ConclusionPTH levels on POD 1 were normal in all patients who had at least one well vascularized parathyroid gland demonstrated during surgery by ICG angiography, and none required treatment for hypoparathyroidism. (Source: British Journal of Surgery)
Source: British Journal of Surgery - February 11, 2016 Category: Surgery Authors: J. Vidal Fortuny, V. Belfontali, S. M. Sadowski, W. Karenovics, S. Guigard, F. Triponez Tags: Original article Source Type: research
American Thyroid Association Statement on Remote Access Thyroid Surgery.
CONCLUSIONS: Remote access thyroidectomy has a role in a small group of patients who fit into strict selection criteria. These approaches require an additional level of expertise, and, therefore, should be done by surgeons performing a high volume of thyroid and robotic surgery. PMID: 26858014 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - February 10, 2016 Category: Endocrinology Tags: Thyroid Source Type: research
Comparison of Bilateral Axillo-Breast Approach Robotic Thyroidectomy with Open Thyroidectomy for Graves’ Disease
Conclusions BABA RT for Graves’ disease showed comparable surgical completeness and complications to conventional OT. BABA RT can be recommended as an alternative surgical option for patients with Graves’ disease who are concerned about cosmesis. (Source: World Journal of Surgery)
Source: World Journal of Surgery - February 10, 2016 Category: Surgery Source Type: research
The Overwhelming Majority but not All Motor Fibers of the Bifid Recurrent Laryngeal Nerve are Located in the Anterior Extralaryngeal Branch
Conclusions The motor fibers of the RLN are located in the anterior extralaryngeal branch in the vast majority of but not in all patients. In rare cases, the motor fibers for adduction or abduction are located in the posterior branch of the RLN. As the bifid nerves are more prone to injury than non-branched nerves, meticulous dissection is recommended to assure preservation of all the branches of the RLN during thyroidectomy. (Source: World Journal of Surgery)
Source: World Journal of Surgery - February 10, 2016 Category: Surgery Source Type: research
Partial Thyroidectomy for Papillary Thyroid Microcarcinoma: Is Completion Total Thyroidectomy Indicated?
Conclusions Thyroid lobectomy is an effective surgical strategy to manage papillary microcarcinomas with low complications. Routine completion thyroidectomy is not mandatory. Appropriate selection excluding high-risk patients is of paramount importance in order to achieve the best results. (Source: World Journal of Surgery)
Source: World Journal of Surgery - February 10, 2016 Category: Surgery Source Type: research
Concurrent Hypoparathyroidism Is Associated with Impaired Physical Function and Quality of Life in Hypothyroidism
This article is protected by copyright. All rights reserved (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - February 10, 2016 Category: Orthopaedics Authors: Tanja Sikjaer, Emil Moser, Lars Rolighed, Line Underbjerg, Lise Sofie Bislev, Leif Mosekilde, Lars Rejnmark Tags: Original Article Source Type: research
Track Recurrence After Robotic Transaxillary Thyroidectomy; A Case Report Highlighting The Importance of Controlled Surgical Indications and Addressing Unprecedented Complications.
CONCLUSIONS: While tailoring the surgical strategy undertaken to patients' concerns and desires is important, abiding to fundamental onco-surgical principles is a priority. Furthermore, unconventional complications associated with novel surgical procedures should be properly evaluated and addressed. PMID: 26850129 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - February 9, 2016 Category: Endocrinology Tags: Thyroid Source Type: research
Acute Mania Induced by Hypothyroidism in a Male Patient After Thyroidectomy.
Authors: Morgado P, Mendonça-Gonçalves M PMID: 26844967 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - February 9, 2016 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research
Economic analysis of routine neuromonitoring of recurrent laryngeal nerve in total thyroidectomy.
CONCLUSION: Routine neuromonitoring in total thyroidectomy with low risk of recurrent laryngeal nerve injury is neither cost-useful nor cost-effective in the Colombian health system. PMID: 26849698 [PubMed - as supplied by publisher] (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - February 9, 2016 Category: Global & Universal Tags: Biomedica Source Type: research
Effect of Thyrotropin Suppression Therapy on Bone in Thyroid Cancer Patients
Conclusion. Studies to date have yielded conflicting results on the skeletal effects of thyrotropin suppression therapy and a knowledge gap remains, especially for older adults and men. Existing data should be cautiously interpreted because of the variable quality and heterogeneity. Identifying groups at risk of adverse effects from thyrotropin suppression therapy will be instrumental to providing focused and tailored thyroid cancer treatment. Implications for Practice: The standard treatment for thyroid cancer includes total thyroidectomy with or without radioactive iodine ablation, often followed by thyrotropin suppress...
Source: The Oncologist - February 8, 2016 Category: Cancer & Oncology Authors: Papaleontiou, M., Hawley, S. T., Haymart, M. R. Tags: Endocrinology Source Type: research
Minimally invasive follicular thyroid carcinomas: prognostic factors
Abstract Although minimally invasive follicular thyroid carcinoma (MI-FTC) is regarded as an indolent tumour, treatment strategies remain controversial. Our aim was to investigate the outcome for patients with MI-FTC and to identify prognostic parameters to facilitate adequate treatment and follow-up. This retrospective follow-up study involved all cases of MI-FTC operated at the Karolinska University Hospital between 1986 and 2009. Outcome was analysed using death from MI-FTC as endpoint. Fifty-eight patients (41 women and 17 men) with MI-FTC were identified. The median follow-up time was 140 (range 21–308) mon...
Source: Endocrine - February 8, 2016 Category: Endocrinology Source Type: research
Intra‐operative neuromonitoring of the vagus nerve during thyroidectomy. A prospective study
ConclusionIONM of the vagus nerve during thyroidectomy may accurately predict postoperative vocal fold palsy. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - February 8, 2016 Category: ENT & OMF Authors: N. Klopp‐Dutote, A. Biet‐Hornstein, G. Guillaume‐Souaid, V. Strunski, C. Page Tags: Original Article Source Type: research
The impact of perioperative dexamethasone on swallowing impairment score after thyroidectomy: a retrospective study of 118 total thyroidectomies
(Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - February 8, 2016 Category: ENT & OMF Authors: S.T. Exarchos, V.A. Lachanas, S. Tsiouvaka, M. Tsea, J.K. Hajiioannou, C.E. Skoulakis, J.G. Bizakis Tags: Correspondence: Our Experience Source Type: research
BRAF V600E detection in cytological thyroid samples: A key component of the decision tree for surgical treatment of papillary thyroid carcinoma
ConclusionThe preoperative knowledge of the V600E mutation status is fundamental to plan total thyroidectomy with certainty and should be part of the decision tree for the management of thyroid nodules. © 2016 Wiley Periodicals, Inc. Head Neck, 2016 (Source: Head and Neck)
Source: Head and Neck - February 8, 2016 Category: ENT & OMF Authors: Jean‐François Collet, Roger Lacave, Sylvain Hugonin, Virginie Poulot, Marc Tassart, Anne Fajac Tags: Original Article Source Type: research
Impact of co‐existent thyroiditis on clinical outcome in papillary thyroid carcinoma with high preoperative serum antithyroglobulin antibody: a retrospective cohort study
ConclusionResidual/recurrent tumour rate was lower in PTC patients with co‐existent CLT than in those without CLT. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - February 7, 2016 Category: ENT & OMF Authors: H.‐Y. Nam, H.Y. Lee, G.C. Park Tags: Original Article Source Type: research
Incidental Gallbladder Cancer Visualized From Posttreatment 131I Whole-Body Scan
Abstract: A 72-year-old woman with papillary thyroid cancer post-total thyroidectomy was referred for post-131I treatment whole-body scan. Images revealed focal uptake within the gallbladder. Cholecystectomy was subsequently performed, and the pathology report showed well-differentiated adenocarcinoma. Given a history of papillary thyroid cancer, the iodine uptake was reasonably explained as metastasis; however, gallbladder metastasis was extremely infrequent. Literature described the incidental radioiodine retention in the gallbladder as false-positive findings, which can be normal variants or benign hepatobiliary conditi...
Source: Clinical Nuclear Medicine - February 6, 2016 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Importance of the intraoperative appearance of preserved parathyroid glands after total thyroidectomy
Conclusion The macroscopic appearance of preserved parathyroid glands and the number of well-preserved parathyroid glands after thyroidectomy proved effective in predicting post-thyroidectomy hypocalcemia. (Source: Surgery Today)
Source: Surgery Today - February 5, 2016 Category: Surgery Source Type: research
Iatrogenic Subclinical Hyperthyroidism Does Not Promote Weight Loss.
CONCLUSIONS: Among total thyroidectomy patients, weight change did not differ between SCH patients and euthyroid patients at years 1 through 3. As such, the use of levothyroxine to induce SCH did not lead to long-term weight change when compared with euthyroid patients. PMID: 26840964 [PubMed - as supplied by publisher] (Source: Southern Medical Journal)
Source: Southern Medical Journal - February 4, 2016 Category: Journals (General) Tags: South Med J Source Type: research
Comparison of antithyroglobulin antibodies concentrations before and after ablation with 131I as predictor of structural disease in differentiated thyroid carcinoma patients with undetectable basal thyroglobulin and negative neck ultrasonography.
CONCLUSIONS: Among patients with undetectable Tg, negative US, and positive TgAb after ablation with 131I, the frequency of structural disease was < 5% in patients with > 50% reduction in TgAb. Among patients without a significant reduction in TgAb, approximately 10% of low-risk patients and > 20% of intermediate-risk patients had structural disease. These results help define the indication for imaging methods other than US during initial assessment and long-term follow-up. PMID: 26831821 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - February 3, 2016 Category: Endocrinology Tags: Thyroid Source Type: research
Apparently intrathyroid papillary thyroid carcinoma > 1 cm and ≤ 4 cm: Is the need for completion thyroidectomy common among patients submitted to lobectomy?
This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - February 3, 2016 Category: Endocrinology Authors: Pedro Weslley Rosario, Gabriela Franco Mourão, Maria Regina Calsolari Tags: Letter Source Type: research
Malignant melanoma arising in melanin-producing medullary thyroid carcinoma
Conclusion Malignant melanoma arising in MTC may have a favorable prognosis. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - February 3, 2016 Category: Surgery Source Type: research
Pre-ablation stimulated thyroglobulin is a better predictor of recurrence in pathological N1a papillary thyroid carcinoma than the lymph node ratio
Conclusion A high pre-ablation sTg level is a better predictor of recurrence in pathological N1a PTC than a high LNR value. Careful follow-up of patients with this risk factor is recommended. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - February 2, 2016 Category: Cancer & Oncology Source Type: research
Management of hereditary medullary thyroid carcinoma
Abstract Hereditary medullary thyroid carcinoma (MTC) represents up to one-third of MTC cases and includes multiple endocrine neoplasia syndrome type 2A (and its variant familial MTC) and 2B. The aim of this paper is to provide an overview of the disease focusing on the management of hereditary MTC patients, who have already developed tumor, as well as discuss the recommended approach for asymptomatic family members carrying the same mutation. A PubMed search was performed to review recent literature on diagnosis, genetic testing, and surgical and medical management of hereditary MTC. The wide use of genetic testi...
Source: Endocrine - February 2, 2016 Category: Endocrinology Source Type: research
The Novel Transvestibule Approach for Endoscopic Thyroidectomy: A Case Series
Conclusions: Transvestibule endoscopic thyroidectomy is feasible, with a satisfactory cosmetic effect; yet, further improvement of surgical techniques are required on account of the complexity of the surgical procedure and the prolonged operation time. (Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques)
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - February 1, 2016 Category: Surgery Tags: Online Articles: Technical Reports Source Type: research
Optimal Cut-Off Values of Lymph Node Ratio Predicting Recurrence in Papillary Thyroid Cancer
In this study, we determined the optimal cut-off values of LNRs for the prediction of recurrence in PTC patients. This large cohort study retrospectively evaluated 2294 patients who had undergone total thyroidectomy for PTC at a single institution from October 1985 to June 2009. The prediction probability of central LNR (cLNR, level VI) and total LNR (tLNR, levels II–VI) were estimated by binominal logistic regression analysis. Hazard ratios of the cut-off LNR values for cancer recurrence were calculated for relevant covariates using multivariate Cox regression analyses. Kaplan–Meier analyses were also utilized to ass...
Source: Medicine - February 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Seasonal Difference in Postthyroidectomy Hypocalcemia: A Montreal-Based Study
Conclusion In this study, patients undergoing thyroidectomy in the winter months were more likely to develop postoperative hypocalcemia when compared with those operated in the summer. Further studies are needed to understand the role of vitamin D in the observed seasonal difference in hypocalcemia rates. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - February 1, 2016 Category: ENT & OMF Authors: Mascarella, M. A., Forest, V.-I., Nhan, C., Leboeuf, R., Tamilia, M., Mlynarek, A. M., Payne, R. J. Tags: Endocrine Surgery Source Type: research
Predictors for papillary thyroid cancer persistence and recurrence: a retrospective analysis with a 10‐year follow‐up cohort study
ConclusionsThe best predictors of persistence were tumor size and macroscopic lymph node metastasis; when the initial surgery is of quality, the recurrence depends more on tumor's biology aspects.This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - February 1, 2016 Category: Endocrinology Authors: Taciana Padilha Castro, William Waissmann, Taynãna César Simões, Rossana Corbo R. de Mello, Denise P. Carvalho Tags: Original Article Source Type: research
Recombinant human thyrotropin‐stimulated thyroglobulin level at the time of radioactiveiodine ablation is an independent prognostic marker of differentiated thyroid carcinoma in the setting of prophylactic central neck dissection
ConclusionA low stimulated serum Tg level at rhTSH‐aided RAI ablation may be a favorable prognostic marker in the setting of prophylactic CND.This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - February 1, 2016 Category: Endocrinology Authors: Jae Hoon Moon, June Young Choi, Woo‐Jin Jeong, Soon‐Hyun Ahn, Won Woo Lee, Kyoung Min Kim, Sung Hee Choi, Soo Lim, Young Joo Park, Ka Hee Yi, Do Joon Park, Hak Chul Jang Tags: Original Article Source Type: research
Chyle leak: an unusual complication after total thyroidectomy and central neck dissection
Abstract Chyle leak is an established but unusual complication after total thyroidectomy plus central compartment neck dissection. It can potentially lead to severe electrolyte disturbances, protein depletion, malnutrition and impaired immunity. Its management varies with the severity of presentation. Majority of leaks are low output type and can be successfully managed with conservative measures. Here we present a case of low output chyle leak after total thyroidectomy plus central neck dissection in a 62‐year‐old lady with papillary thyroid cancer whose leakage was resolved with prolonged pressure dressing and medium...
Source: Surgical Practice - February 1, 2016 Category: Surgery Authors: Hon‐Ting Lok, Shirley Yuk‐Wah Liu, Simon Kin‐Hung Wong, Enders Kwok‐Wai Ng Tags: CASE REPORT Source Type: research
Prognostic implications of lymph node yield in central and lateral neck dissections for well-differentiated papillary thyroid carcinoma.
Conclusions Higher LNY in central and lateral neck dissections is associated with lower rates of papillary thyroid cancer recurrence in the central and lateral neck. To minimize the risk of recurrence and the need for secondary therapy with revision surgery and/or radiation, surgeons should perform thorough, compartment-oriented central and lateral neck dissections when nodal surgery is undertaken. PMID: 26825749 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - January 31, 2016 Category: Endocrinology Tags: Thyroid Source Type: research
Clinicopathologic characteristics of familial versus sporadic papillary thyroid carcinoma.
In this study, we investigated the clinicopathologic features of familial papillary thyroid carcinoma (PTC) compared with its sporadic counterpart. We used data from our hospital between 2008 and 2014 to compare the features of 24 familial PTC with 80 sporadic PTC. The prevalence of familial PTC was 1.5%; 25% of familial PTC exhibited a parent-offspring relationship, and 75% exhibited a sibling relationship. There were significant differences in terms of Hashimoto's thyroiditis, nodular goiter, multicentricity, bilaterality, histologic variant, T stage and N stage between the familial and sporadic PTC groups (all p < 0....
Source: Acta Otorhinolaryngologica Italica - January 30, 2016 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research
Germline mutation carriers in Japanese patients with apparently sporadic medullary thyroid carcinoma: A single institution experience
Genetic testing for RET germline mutation can be useful to distinguish whether a patient with medullary thyroid carcinoma (MTC) is genuinely sporadic or hereditary. Conducting a routine preoperative germline RET genetic screening for all patients with MTC has the clinical benefit, i.e., avoidance of unnecessary total thyroidectomy in the selected patients. We sought to clarify the incidence of germline RET mutation carriers in Japanese patients with apparently sporadic MTC and to address the differences in clinicopathological characteristics between true sporadic MTC and hereditary MTC in these patients, all of whom were t...
Source: Auris, Nasus, Larynx - January 30, 2016 Category: ENT & OMF Authors: Minoru Kihara, Akira Miyauchi, Kana Yoshioka, Hitomi Oda, Ayako Nakayama, Hisanori Sasai, Tomonori Yabuta, Hiroo Masuoka, Takuya Higashiyama, Mitsuhiro Fukushima, Yasuhiro Ito, Kaoru Kobayashi, Akihiro Miya Source Type: research
Effect of laryngotracheal topical anesthesia on recurrent laryngeal nerve monitoring during thyroid Surgery
Intraoperative neuromonitoring of the recurrent laryngeal nerve (RLN) is often used as an adjunct for RLN identification and preservation during thyroidectomies. Laryngotracheal anesthesia (LTA) with topical lidocaine reduces coughing upon emergence from anesthesia and in the immediate postoperative period; however, its use is prohibited with concerns that it could decrease the sensitivity of the intraoperative neuromonitoring. We hypothesize that there is no difference in measurements of nerve conduction made before and after LTA administration. (Source: Journal of Clinical Anesthesia)
Source: Journal of Clinical Anesthesia - January 29, 2016 Category: Anesthesiology Authors: Justin Pachuski, Sonia Vaida, Kathleen Donahue, John Roberts, Allen Kunselman, Benjamin Oberman, Hetal Patel, David Goldenberg Tags: Original contribution Source Type: research
Cerebral blood flow in transient hypothyroidism after thyroidectomy: Arterial spin labeling magnetic resonance study.
CONCLUSIONS: This study revealed alterations of rCBF in patients with transient hypothyroidism. ASL is helpful for understanding of the effects of hypothyroidism on the brain. PMID: 26812287 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - January 28, 2016 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
Motor and somatosensory evoked potential spinal cord monitoring during intubation and neck extension for thyroidectomy in a Down syndrome boy with atlantoaxial instability
Abstract Intubation or neck extension can compress the spinal cord in patients with craniocervical instability. Protective motor evoked potential (MEP) and somatosensory evoked potential (SEP) monitoring of these maneuvers is an obvious consideration when these patients undergo already-monitored spinal surgery, but might be overlooked when they undergo other normally unmonitored procedures. Here we report monitoring intubation and neck extension for the unusual indication of thyroidectomy in a Down syndrome boy with atlantoaxial instability. Transcranial electric stimulation thenar MEPs and optimized median nerve ...
Source: Journal of Clinical Monitoring and Computing - January 28, 2016 Category: Information Technology Source Type: research
Voice Changes after Late Recurrent Laryngeal Nerve Identification Thyroidectomy
To assess voice changes in patients after thyroidectomy where the recurrent laryngeal nerve (RLN) was found late in the thyroid dissection and where the RLN was not injured (late RLN identification technique). (Source: Journal of Voice)
Source: Journal of Voice - January 28, 2016 Category: ENT & OMF Authors: Ezzeddin Elsheikh, Amal Saeed Quriba, Mohammad Waheed El-Anwar Source Type: research
Does dexmedetomidine improve analgesia of superficial cervical plexus block for thyroid surgery?
Conclusion: Combination of 0.5% ropivacaine and dexmedetomidine for BSCPB provided significantly prolonged and better quality of postoperative analgesia and patient satisfaction than with 0.5% ropivacaine alone in patients undergoing thyroidectomy. (Source: Indian Journal of Anaesthesia)
Source: Indian Journal of Anaesthesia - January 26, 2016 Category: Anesthesiology Authors: BS SantoshSripada Gopalakrishna Mehandale Source Type: research
Anaesthesia for robotic thyroidectomy for thyroid cancer and review of literature
Shagun Bhatia Shah, Uma Hariharan, Anita Kulkarni, Namrata Choudhary DabasIndian Journal of Anaesthesia 2016 60(1):55-57Robotic thyroidectomy (RT) is a new gasless, scarless technique which utilises the da Vinci™ surgical robot to excise thyroid tumours. Anaesthetic management must be modified according to the patient position and robotic surgery equipment. Anaesthesiologists need to be geared up to face the new challenges posed by advancements in surgical techniques in order to maintain patient safety. Another vital aspect of this surgery is documenting possible recurrent laryngeal nerve palsy, for which a C-...
Source: Indian Journal of Anaesthesia - January 26, 2016 Category: Anesthesiology Authors: Shagun Bhatia ShahUma HariharanAnita KulkarniNamrata Choudhary Dabas Source Type: research
Carbon dioxide embolism during endoscopic thyroidectomy
Sunil Rajan, Jerry Paul, Lakshmi KumarIndian Journal of Anaesthesia 2016 60(1):65-66 (Source: Indian Journal of Anaesthesia)
Source: Indian Journal of Anaesthesia - January 26, 2016 Category: Anesthesiology Authors: Sunil RajanJerry PaulLakshmi Kumar Source Type: research
Thyroid carcinoma in children, adolescents and adults, both spontaneous and after childhood radiation exposure
Conclusion: Ultrasound screening is required for early diagnosis as small nodule size is not predictive of benign histology or absence of metastases. Central node clearance provides better outcome. Despite metastatic disease at presentation for some, prognosis is favourable. What is Known: • Incidence of thyroid cancer has been increasing and radiation exposure in childhood cancer survivors is clearly linked to risk. • Published guidelines in many places can only provide very low level evidence due to ...
Source: European Journal of Pediatrics - January 25, 2016 Category: Pediatrics Source Type: research
Minimally invasive video-assisted thyroidectomy (MIVAT) from A to Z
This article provides a detailed description of this minimally invasive, maximally effective and patient satisfying procedure so that it may be adopted by more surgeons around the globe for better patient care and to also encourage the development of further future advancements. (Source: Surgery Today)
Source: Surgery Today - January 24, 2016 Category: Surgery Source Type: research
Low Postoperative Nonstimulated Thyroglobulin as a Criterion for the Indication of Low Radioiodine Activity in Patients with Papillary Thyroid Cancer of Intermediate Risk “with Higher Risk Features”
ConclusionsWe conclude that in intermediate‐risk patients “with higher risk features”, low nonstimulated Tg measured with a second‐generation assay can be used as criterion for the administration of low 131I activities (1850 MBq or less).This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - January 23, 2016 Category: Endocrinology Authors: Pedro Weslley Rosario, Gabriela Franco Mourão, Maria Regina Calsolari Tags: Original Article Source Type: research
Chronic post-thyroidectomy pain: incidence, typology, and risk factors
Publication date: Available online 22 January 2016 Source:Anaesthesia Critical Care & Pain Medicine Author(s): Jean-Michel Wattier, Robert Caïazzo, Grégoire Andrieu, Eric Kipnis, François Pattou, Gilles Lebuffe Chronic postoperative pain exists in varying degrees for every type of surgery. An evaluation of the incidence, the typology and predictive factors of chronic pain was carried out at 3 and 6 months after thyroidectomy. A prospective observational study, having included each of the patients prior to their thyroidectomy, was carried out over 12 months. The patients used an 11-point numerical rating ...
Source: Anaesthesia, Critical Care and Pain Medicine - January 23, 2016 Category: Anesthesiology Source Type: research
DNA degradation in liquid‐based cytology and its comparison with conventional smear
ConclusionLBC may have disadvantages in long‐term DNA preservation because of its accelerated DNA degradation compared with alcohol‐fixed CS. Using primers to amplify shorter size fragments might be helpful in mitigating loss of signal due to DNA degradation in LBC. Diagn. Cytopathol. 2016. © 2016 Wiley Periodicals, Inc. (Source: Diagnostic Cytopathology)
Source: Diagnostic Cytopathology - January 23, 2016 Category: Pathology Authors: Wook Youn Kim, Seo Young Oh, Hyunkyung Kim, Tae Sook Hwang Tags: Molecular Cytpathology Source Type: research
Expression of ECM1 and MMP-2 in follicular thyroid lesions among Egyptians.
CONCLUSIONS: MMP-2 protein and ECM1 gene are useful preoperative markers for defining malignancy in suspicious thyroid nodules. PMID: 25812648 [PubMed - in process] (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - January 22, 2016 Category: Cancer & Oncology Tags: Cancer Biomark Source Type: research
Comparing transaxillary robotic surgery (TARS) with open thyroidectomy in a Western population: A case control study
Transaxillary robotic surgery (TARS) was pioneered in South Korea where cultural factors, anthropometry and remuneration favour this approach. Moreover, small thyroid nodules account for the majority of cases due to a national thyroid cancer screening programme. The technique has not been evaluated in the United Kingdom where larger thyroid nodules tend to undergo surgery in a patient population with a significantly higher body mass index (BMI). (Source: International Journal of Surgery)
Source: International Journal of Surgery - January 22, 2016 Category: Surgery Authors: Asit Arora, George Garas, Sunil Sharma, Keerthini Muthuswamy, James Budge, Fausto Palazzo, Ara Darzi, Neil Tolley Tags: Original Research Source Type: research
Comparing transaxillary robotic thyroidectomy with conventional surgery in a UK population: A case control study
Transaxillary robotic thyroid surgery was pioneered in South Korea where cultural factors, anthropometry and remuneration favour this. Small thyroid nodules account for the majority of cases due to a national thyroid cancer screening programme. However, the technique has not been evaluated in the United Kingdom where larger thyroid nodules tend to undergo surgery in a patient population with a higher body mass index (BMI). (Source: International Journal of Surgery)
Source: International Journal of Surgery - January 22, 2016 Category: Surgery Authors: Asit Arora, George Garas, Sunil Sharma, Keerthini Muthuswamy, James Budge, Fausto Palazzo, Ara Darzi, Neil Tolley Tags: Original research Source Type: research
Impact of microscopic extra‐nodal extension (ENE) on locoregional recurrence following curative surgery for papillary thyroid carcinoma
ConclusionsPatients with microscopic ENE were significantly more likely to have biochemical incompleteness after initial therapy. After adjusting for other significant primary and nodal characteristics, microscopic ENE was an independent factor for LRR in patients with cN1. J. Surg. Oncol. © 2016 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology)
Source: Journal of Surgical Oncology - January 21, 2016 Category: Cancer & Oncology Authors: Brian H.‐H. Lang, Tony W.H. Shek, Koon Yat Wan Tags: Research Article Source Type: research
Graves' Disease Pharmacotherapy in Women of Reproductive Age
Graves' disease is an autoimmune disorder in which inappropriate stimulation of the thyroid gland results in unregulated secretion of thyroid hormones resulting in hyperthyroidism. Graves' disease is the most common cause of autoimmune hyperthyroidism during pregnancy. Treatment options for Graves' disease include thioamide therapy, partial or total thyroidectomy, and radioactive iodine. In this article, we review guideline recommendations for Graves' disease treatment in women of reproductive age including the recent guideline from the American College of Obstetricians and Gynecologists. Controversy regarding appropriate ...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - January 21, 2016 Category: Drugs & Pharmacology Authors: Jeremy J. Prunty, Crystal D. Heise, David G. Chaffin Tags: Reviews of Therapeutics Source Type: research
Preablative stimulated thyroglobulin correlates to new therapy response system in differentiated thyroid cancer.
CONCLUSIONS: Ps-Tg has a great performance in predicting therapeutic response and providing incremental value for decision making of RAI therapy, especially for patients with high ps-Tg level. PMID: 26789779 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - January 20, 2016 Category: Endocrinology Authors: Yang X, Liang J, Li T, Zhao T, Lin Y Tags: J Clin Endocrinol Metab Source Type: research