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Thyroidectomy

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Prediction of central LN metastasis in PTMC
Central compartment lymph node metastases (LNM) is found in 40 – 60% of patients with Papillary thyroid microcarcinoma (PTMC). The standard care for LNM is total thyroidectomy with ‘therapeutic’ cervical lymph node dissection. However whether routine central lymph node dissection should be performed in the PTMC patients without evident LNM remains controversial. Yang et al, report on their study to determine the factors predictive of central compartment LNM, as well as their attempt to create a nomogram to estimate the probability of central compartment LNM in PTMC. The study population consi...
Source: Society for Endocrinology - August 28, 2014 Category: Endocrinology Source Type: news

Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer
Conclusions: Specific sonographic findings (hypoechogenicity or marked hypoechogenicity, and calcification) suggest LNM. (Source: World Journal of Surgical Oncology)
Source: World Journal of Surgical Oncology - August 28, 2014 Category: Cancer & Oncology Authors: Yoon Se LeeYun-Sung LimJin-Choon LeeSoo-Geun WangSeok-Man SonSang-Soo KimIn-Ju KimByung-Joo Lee Source Type: research

Association between idiopathic retroperitoneal fibrosis and autoimmune thyroiditis: A case-control study.
CONCLUSIONS: IRF patients have a higher risk of HT compared to controls. Thyroid function should be monitored in patients with IRF. PMID: 25172237 [PubMed - as supplied by publisher] (Source: Autoimmunity Reviews)
Source: Autoimmunity Reviews - August 27, 2014 Category: Allergy & Immunology Authors: Ceresini G, Urban ML, Corradi D, Lauretani F, Marina M, Usberti E, Palmisano A, Buzio C, Vaglio A Tags: Autoimmun Rev Source Type: research

Papillary thyroid cancer: factors involved in restaging N1 disease after total thyroidectomy and radioactive iodine treatment.
Conclusion: Patients with PTC and N1 disease treated with total thyroidectomy and RAI have a significant risk of persistent disease at early and late follow-up. The extension of the primary tumor at diagnosis appears to be the only significant predictor of persistency in these patients. PMID: 25157544 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - August 26, 2014 Category: Endocrinology Authors: Guy A, Hirsch D, Shohat T, Bachar G, Tirosh A, Robenshtok E, Shimon I, Benbassat CA Tags: J Clin Endocrinol Metab Source Type: research

Minimally Invasive Thyroidectomy Safe in Some PatientsMinimally Invasive Thyroidectomy Safe in Some Patients
In select patients, minimally invasive thyroidectomy (MIT) through a 2-cm incision without video assistance is a safe and equally effective option to traditional open thyroidectomy, according to U.S. doctors. Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - August 25, 2014 Category: Surgery Tags: General Surgery News Source Type: news

Label-free Intraoperative Parathyroid Localization with Near-Infrared Autofluorescence Imaging.
Conclusion: NIR fluorescence imaging represents a highly sensitive, real-time, label-free tool for parathyroid localization during surgery. The elegance and effectiveness of NIR autofluorescence imaging of the parathyroid gland makes it highly attractive for clinical application in endocrine surgery. PMID: 25148235 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - August 22, 2014 Category: Endocrinology Authors: McWade MA, Paras C, White LM, Phay JE, Solórzano CC, Broome JT, Mahadevan-Jansen A Tags: J Clin Endocrinol Metab Source Type: research

Accuracy of unstimulated Basal serum thyroglobulin levels in assessing the completeness of thyroidectomy.
CONCLUSIONS: The positive basal Tg (> 0.5 ng/mL) level accurately indicated the functional thyroid remnant after total thyroidectomy. The negative Tg (< 0.5 ng/mL) level supported complete excision of the thyroid gland. The surgical completeness of total thyroidectomy was accurately evaluated based on the serum Tg levels. Therefore, serum Tg levels should be measured in postoperative follow-up to determine the completeness of total thyroidectomy. PMID: 25110541 [PubMed] (Source: Clin Med Res)
Source: Clin Med Res - August 15, 2014 Category: Research Authors: Gurleyik E, Dogan S Tags: J Clin Med Res Source Type: research

Volume changes in remnant thyroid tissue after thyroidectomy in Graves disease.
CONCLUSION: Age and residual volume ratio were the most powerful two factors in this study. PMID: 25103076 [PubMed - in process] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - August 14, 2014 Category: Journals (General) Authors: Chen PY, Chao CM, Wu TJ, Huang SM Tags: J Formos Med Assoc Source Type: research

The risk of second primary malignancy is increased in differentiated thyroid cancer patients with a cumulative 131I dose over 37 GBq
ConclusionA cumulative 131I dose < 37.0 GBq did not increase the risk of SPM. A cumulative 131I dose ≥ 37.0 GBq increased the risk of SPM and SPM‐related mortality and decreased the DTC‐specific mortality, resulting in a similar all‐cause mortality compared with the low activity RAI group. Using repeated high dose RAI for treating RAI‐responsive but persistent DTC patients needs careful consideration of the individual benefits from RAI versus the risk of developing SPM.This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - August 14, 2014 Category: Endocrinology Authors: Ah Reum Khang, Sun Wook Cho, Hoon Sung Choi, Hwa Young Ahn, Won Sang Yoo, Kyung Won Kim, Keon Wook Kang, Ka Hee Yi, Do Joon Park, Dong Soon Lee, June‐Key Chung, Bo Youn Cho, Young Joo Park Tags: Original Article Source Type: research

Preoperative carbohydrate treatment for enhancing recovery after elective surgery.
CONCLUSIONS: Preoperative carbohydrate treatment was associated with a small reduction in length of hospital stay when compared with placebo or fasting in adult patients undergoing elective surgery. It was found that preoperative carbohydrate treatment did not increase or decrease postoperative complication rates when compared with placebo or fasting. Lack of adequate blinding in many studies may have contributed to observed treatment effects for these subjective outcomes, which are subject to possible biases. PMID: 25121931 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 14, 2014 Category: Journals (General) Authors: Smith MD, McCall J, Plank L, Herbison GP, Soop M, Nygren J Tags: Cochrane Database Syst Rev Source Type: research

Tall Cell Variant of Papillary Thyroid Carcinoma in Children: Report of Three Cases With Long-Term Follow-Up From a Single Institution
Papillary thyroid carcinoma (PTC), tall cell (TC) variant, is exceptional in children. In adults it represents about 20% of PTCs, featuring a high-risk neoplasm, with a 4-fold risk of relapse and a 20-fold relapse-related risk of death. Out of 42 cases of pediatric PTCs, we found 3 cases of PTC-TC (7%) with clinical data at onset and follow-up up to June 2014. They were 3 females aged 13, 15, and 15 years. Local extrathyroid extension was present in 2 cases. Neither nodal nor distant metastases were found. Two patients underwent hemithyroidectomy and 1 patient a total thyroidectomy, followed in all cases by life-long suppr...
Source: International Journal of Surgical Pathology - August 13, 2014 Category: Pathology Authors: Collini, P., Massimino, M., Mattavelli, F., Barisella, M., Podda, M., Rosai, J. Tags: Original Articles Source Type: research

Nodular recurrence and hypothyroidism following partial thyroidectomy for benign nodular thyroid disease in children and adolescents
In this study, we aimed to answer the following questions: Does a nodule recurrence occur in the remainder lobe? Is a post-operative thyroxine treatment necessary? (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - August 8, 2014 Category: ENT & OMF Authors: M. Akkari, D. Schmitt, C. Jeandel, I. Raingeard, C. Blanchet, C. Cartier, R. Garrel, B. Guerrier, M. Makeieff, M. Mondain Source Type: research

Levothyroxine replacement in hypothyroid humans reduces myocardial lipid load and improves cardiac function.
Conclusion: Here we show that levothyroxine treatment reduces lipid accumulation in the heart and increases cardiac output in overtly hypothyroid patients. These results could in part explain the increased risk of death and heart failure in hypothyroid patients. PMID: 25105733 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - August 8, 2014 Category: Endocrinology Authors: Scherer T, Wolf P, Winhofer Y, Duan H, Einwallner E, Gessl A, Luger A, Trattnig S, Hoffmann M, Niessner A, Baumgartner-Parzer S, Krššák M, Krebs M Tags: J Clin Endocrinol Metab Source Type: research

The role of IgG4 (+) plasma cells in the association of Hashimoto's thyroiditis with papillary carcinoma
In this study, it was intended to re‐classify the HT diagnosed cases on the basis of the existence of IgG4 (+) plasma cells; to investigate the clinicopathologic and histopathologic features of the both groups; and in addition, to evaluate the papillary carcinoma prevalence in IgG4 (+) and IgG4 (−) HT cases as well as the prognostic parameters between these groups. Totally 59 cases between the years 2008–2013, 29 of which contain Hashimoto thyroiditis diagnosis in total thyroidectomy materials, and 30 of which contain the diagnosis of HT+papillary carcinoma, were included in the study. The materials were immunohistoc...
Source: APMIS - August 6, 2014 Category: Research Authors: Funda Taşli, Güliz Özkök, Asuman Argon, Didem Ersöz, Ayşe Yağci, Adam Uslu, Nazif Erkan, Tarik Salman, Enver Vardar Tags: Original Article Source Type: research

Endoscopic thyroid surgery via a breast approach: a single institution's experiences
Conclusions: For patients with benign and low-risk malignant thyroid disease, endoscopic thyroidectomy via a breast approach is a safe, feasible, and minimally invasive surgical method with minimal complications. (Source: BMC Surgery)
Source: BMC Surgery - August 5, 2014 Category: Surgery Authors: Yong-Seok KimKyu-Hwa JooSun-Cheol ParkKee-Hwan KimChang-Hyuck AhnJeong-Soo Kim Source Type: research

Endoscopic thyroid surgery via a breast approach: a single institution¿s experiences
Conclusions: For patients with benign and low-risk malignant thyroid disease, endoscopic thyroidectomy via a breast approach is a safe, feasible, and minimally invasive surgical method with minimal complications. (Source: BMC Surgery)
Source: BMC Surgery - August 5, 2014 Category: Surgery Authors: Yong-Seok KimKyu-Hwa JooSun-Cheol ParkKee-Hwan KimChang-Hyuck AhnJeong-Soo Kim Source Type: research

Discussion
Dr Peter Angelos (Chicago, IL): Dr Snyder and colleagues have shown that attention to the incision size can push the surgeon to make smaller incisions. They should be commended for the high quality of surgical care that they provide. Note that the authors have reduced the size of the scar for thyroidectomy from 3.98 to 2.22 cm, and they have improved the baseline high level of satisfaction with the scar from 8.66 to 9.56 (out of a 10-point scale). (Source: Surgery)
Source: Surgery - August 4, 2014 Category: Surgery Source Type: research

Minimally invasive, nonendoscopic thyroidectomy: A cosmetic alternative to robotic-assisted thyroidectomy
We report on minimally invasive thyroidectomy (MIT) through a 2-cm incision without the added need for video assistance and hypothesize similar clinical results to standard open thyroidectomy. (Source: Surgery)
Source: Surgery - August 4, 2014 Category: Surgery Authors: Cara M. Govednik, Samuel K. Snyder, Courtney E. Quinn, Saurabh Saxena, Daniel C. Jupiter Source Type: research

Parathyroid hormone levels 1 hour after thyroidectomy: an early predictor of postoperative hypocalcemia.
CONCLUSION: We found that PTH-1 levels were predictive of symptomatic hypocalcemia 24 hours after thyroidectomy. Routine use of this assay should be considered, as it could prompt the early administration of calcitriol in patients at risk of hypocalcemia and allow for the safe and timely discharge of patients expected to remain eucalcemic. PMID: 25078927 [PubMed - in process] (Source: Canadian Journal of Surgery)
Source: Canadian Journal of Surgery - August 1, 2014 Category: Surgery Authors: AlQahtani A, Parsyan A, Payne R, Tabah R Tags: Can J Surg Source Type: research

Parathyroid hormone levels predict posttotal thyroidectomy hypoparathyroidism.
Abstract We hypothesized that parathyroid hormone (PTH) determination would be the most effective strategy to identify posttotal thyroidectomy hypoparathyroidism (PTTHP) compared with other clinical and laboratory parameters. We retrospectively reviewed our recent experience with total thyroidectomy. We recorded demographics, malignancy, thyroid weight, parathyroid autotransplantation, hospital stay, use of postoperative calcium and hormonally active vitamin D3 (calcitriol), and postoperative serum calcium and PTH levels. Patients were divided into two groups depending on whether supplemental calcitriol was require...
Source: The American Surgeon - August 1, 2014 Category: Surgery Authors: Rivere AE, Brooks AJ, Hayek GA, Wang H, Corsetti RL, Fuhrman GM Tags: Am Surg Source Type: research

False-negative Results with the Bethesda System of Reporting Thyroid Cytopathology: Predictors of Malignancy in Thyroid Nodules Classified as Benign by Cytopathologic Evaluation.
Abstract The benign category of the Bethesda System for reporting thyroid cytopathology (BSRTC) predicts an incidence of malignancy from zero to three per cent. However, recent series report higher rates of malignancy ranging from eight to 14 per cent. Surgery is often performed for reasons other than their fine needle aspiration biopsy (FNAB) such as symptoms, nodule enlargement, or worrisome imaging. We hypothesized that an analysis of patients who underwent thyroidectomy despite a benign FNAB would identify predictors of malignancy, an area not currently addressed by American Thyroid Association guidelines. We p...
Source: The American Surgeon - August 1, 2014 Category: Surgery Authors: Richmond BK, Judhan R, Chong B, Ubert A, AbuRahma Z, Mangano W, Thompson S Tags: Am Surg Source Type: research

Minimally invasive compared with conventional thyroidectomy for nodular goitre.
Abstract Since minimally invasive thyroidectomy was introduced in 1997, different surgical approaches to the thyroid have been described: the minimal neck incision and the anterior chest, areolar breast or axillary access. Whereas conventional open thyroidectomy is suitable for any thyroid disease, minimal neck incision thyroidectomy or extracervical scarless neck thyroidectomy are limited to small-volume disease. In 11 prospective randomized studies and six systematic reviews, minimally invasive video-assisted thyroidectomy via a central or lateral neck approach afforded better cosmesis in the first 3 months than ...
Source: Clinical Breast Cancer - July 28, 2014 Category: Cancer & Oncology Authors: Dralle H, Machens A, Thanh PN Tags: Best Pract Res Clin Endocrinol Metab Source Type: research

Discussion
Dr Sarah Oltmann (Madison, WI): The group from Case Western describes their experience with patients undergoing thyroidectomy for a thyroid FNAB showing AFLUS. During the first 2 years the Bethesda System was implemented at their institution, they performed thyroidectomy on 61 patients with a biopsy result demonstrating AFLUS. On final pathology, six patients ultimately were found to have thyroid cancer. With this in mind, they sought to retrospectively evaluate the preoperative ultrasound evaluation to determine characteristics of the nodule that were associated with malignancy. (Source: Surgery)
Source: Surgery - July 26, 2014 Category: Surgery Source Type: research

Preoperative neck ultrasound in clinical node negative differentiated thyroid cancer.
Conclusion: Preoperative neck US detects more lateral neck disease, leading to an increase in LND with subsequent improvement in Response to Therapy and fewer return to OR for regional recurrence management. PMID: 25062456 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 25, 2014 Category: Endocrinology Authors: Wang LY, Palmer FL, Thomas D, Shaha AR, Shah JP, Patel SG, Tuttle RM, Ganly I Tags: J Clin Endocrinol Metab Source Type: research

Clinical Features and Treatment Outcomes of 41 Dogs with Sublingual Ectopic Thyroid Neoplasia
Conclusions and Clinical ImportanceWhen compared with eutopic thyroid carcinomas, ectopic sublingual thyroid tumors generally have a less aggressive biologic behavior. Many dogs have prolonged survival, even without treatment, although death because of local tumor invasiveness or metastasis can develop in some dogs. Surgical thyroidectomy, including partial hyoidectomy, is generally effective for control of local disease. Administration of radioiodine, alone or in combination with surgical treatment, is recommended for multifocal disease or metastasis. (Source: Journal of Veterinary Internal Medicine)
Source: Journal of Veterinary Internal Medicine - July 23, 2014 Category: Veterinary Research Authors: M.R. Broome, M.E. Peterson, J.R. Walker Tags: Standard Article Source Type: research

Minimally invasive compared with conventional thyroidectomy for nodular goitre
(Source: Best Practice and Research. Clinical Endocrinology and Metabolism)
Source: Best Practice and Research. Clinical Endocrinology and Metabolism - July 19, 2014 Category: Endocrinology Authors: Henning Dralle, Andreas Machens, Phuong Nguyen Thanh Source Type: research

A staged thyroidectomy approach for gastric bypass patients
(Source: The Laryngoscope)
Source: The Laryngoscope - July 18, 2014 Category: ENT & OMF Authors: Zhen Gooi, Bryan K. Ward, David J. Mener, Ozan B. Ozgursoy, Sara I. Pai Tags: Thyroid/Parathyroid Source Type: research

BRAF V600 co-testing in thyroid FNA cytology: short-term experience in a large cancer centre in the UK
Conclusions BRAF V600 mutational analysis can enable single-stage total thyroidectomy for carcinoma if gene mutation is present in preoperative FNA. BRAF V600 co-testing may reduce the need for completion thyroidectomy with implied cost savings and lower patient morbidity associated with completion thyroidectomy when the cytology is inconclusive but where BRAF V600 mutation is identified in preoperative thyroid FNA. (Source: Journal of Clinical Pathology)
Source: Journal of Clinical Pathology - July 16, 2014 Category: Pathology Authors: Poller, D. N., Glaysher, S., Agrawal, A., Caldera, S., Kim, D., Yiangou, C. Tags: Molecular genetics, Endocrine cancer Original article Source Type: research

(11)C-Methionine PET/CT imaging of (99m)Tc-MIBI-SPECT/CT negative patients with primary hyperparathyreoidism and previous neck surgery.
Conclusion: (11)C-Methionine PET/CT is a useful complementary imaging technique to localize parathyroid adenoma or carcinoma in (99m)Tc-MIBI SPECT/CT negative patients. PMID: 25029418 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 16, 2014 Category: Endocrinology Authors: Traub-Weidinger T, Mayerhoefer ME, Koperek O, Mitterhauser M, Duan H, Karanikas G, Niederle B, Hoffmann M Tags: J Clin Endocrinol Metab Source Type: research

Anterior Mediastinal Tracheostomy as Salvage Operation.
CONCLUSIONS: Our experience with AMT as salvage therapy has shown acceptable long-term results if complete resection is achieved. This procedure is not risk free, and very careful patient selection is required because of a tortuous postoperative course, especially in combined pharyngeal-esophageal and vascular reconstruction. PMID: 25038017 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - July 15, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Berthet JP, Garrel R, Gimferrer JM, Paradela M, Marty-Ané CH, Molins L, Gómez-Caro A Tags: Ann Thorac Surg Source Type: research

Effect of clinical nursing pathway for endoscopic thyroidectomy in Chinese patients: A meta‐analysis
The aim of this study was to assess the effect of the use of a clinical nursing pathway for patients undergoing endoscopic thyroidectomy by conducting a meta‐analysis. Electronic databases were searched for relevant controlled trials published prior to August 2013. Only papers that compared the use of a clinical nursing pathway to usual care for patients undergoing endoscopic thyroidectomy were selected. The outcome measures were mean difference and 95% confidence interval for length of hospital stay and hospital charges and risk ratio for patient satisfaction. Six controlled trials were identified. The use of a clinical...
Source: International Journal of Nursing Practice - July 11, 2014 Category: Nursing Authors: Yu Yang, Xinhua Hu, Qiang Zhang, Hui Cao, Jun Li, Junpeng Wang, Yang Shao, Shijie Xin Tags: Research Paper Source Type: research

Total thyroidectomy versus hemithyroidectomy for patients with follicular neoplasm. A cost-utility analysis
Thyroid nodules are a common condition. Overall, 20% of the nodules assessed with FNAB correspond to the follicular pattern. A partial thyroidectomy is the minimal procedure that should be performed to determine the nature of these nodules. Some authors have suggested performing a total thyroidectomy based on the elimination of reoperation and ultrasound follow-up. The aim of this study was to evaluate the most cost-useful surgical strategy in a patient with an undetermined nodule, assessing complications, reoperation, recurrence and costs. (Source: International Journal of Surgery)
Source: International Journal of Surgery - July 10, 2014 Category: Surgery Authors: C. Corso, X. Gomez, A. Sanabria, V. Vega, L.C. Dominguez, C. Osorio Source Type: research

Postoperative PTH monitoring of hypocalcemia expedites discharge after thyroidectomy
Hypocalcemia is the most common complication after total thyroidectomy. Some patients need to stay in the hospital for monitoring of hypocalcemic symptoms and serum calcium levels for several days. We investigated the efficacy and safety of using early postoperative parathyroid hormone (PTH) results for early discharge after thyroidectomy. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - July 9, 2014 Category: Endocrinology Authors: Tam-Lin Chow, Chi-Yee Choi, Annie Nga-King Chiu Source Type: research

Relationship between hypoparathyroidism and the number of parathyroid glands preserved during thyroidectomy
Conclusions: Preservation of all parathyroid glands decreases transient hypoparathyroidism compared with when three or fewer glands are preserved, but does not affect permanent hypoparathyroidism. During total thyroidectomy, preserving at least one parathyroid gland with an intact blood supply appears to be sufficient to prevent permanent hypoparathyroidism when autotransplantation is not performed. (Source: World Journal of Surgical Oncology)
Source: World Journal of Surgical Oncology - July 7, 2014 Category: Cancer & Oncology Authors: Chang Myeon SongJoo Hwan JungYong Bae JiHyun Jung MinYou Hern AhnKyung Tae Source Type: research

The utility of BRAF mutation detection in fine‐needle aspiration biopsy samples read as “suspicious for papillary thyroid carcinoma”
Conclusions: BRAF testing is a useful adjunct to improve PPV for patients with suspicious for PTC cytology. Head Neck, 2014 (Source: Head and Neck)
Source: Head and Neck - July 3, 2014 Category: ENT & OMF Authors: Sebastian M. Jara, Ramneesh Bhatnagar, Hui Guan, Christopher D. Gocke, Syed Z. Ali, Ralph P. Tufano Tags: Original Article Source Type: research

Robotic thyroidectomy learning curve for beginning surgeons with little or no experience of endoscopic surgery
Conclusions: The surgical learning curve for robotic thyroidectomy performed by recently graduated fellowship‐trained surgeons with little or no experience in endoscopic surgery showed excellent results compared with those in a large series of more experienced surgeons. Head Neck, 2014 (Source: Head and Neck)
Source: Head and Neck - July 2, 2014 Category: ENT & OMF Authors: Jae Hyun Park, Jandee Lee, Nor Azham Hakim, Ha Yan Kim, Sang‐Wook Kang, Jong Ju Jeong, Kee‐Hyun Nam, Keum‐Seok Bae, Seong Joon Kang, Woong Youn Chung Tags: Original Article Source Type: research

Pyramidal lobe decreases endogenous TSH stimulation without impact on radio-iodine therapy outcome in patients with differentiated thyroid cancer.
CONCLUSION: Pyramidal lobe decreases endogenous TSH stimulation without impact on radio-iodine therapy outcome in patients with DTC. PMID: 24997767 [PubMed - as supplied by publisher] (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - July 2, 2014 Category: Endocrinology Authors: Sawicka-Gutaj N, Klimowicz A, Sowinski J, Oleksa R, Gryczynska M, Wyszomirska A, Czarnywojtek A, Ruchala M Tags: Ann Endocrinol (Paris) Source Type: research

Pathologic spectrum of lymphocytic infiltration and recurrence of papillary thyroid carcinoma.
CONCLUSION: There was no relationship between PTC prognosis and different grades of LT. Pathologic tumor size and taller than wide shape on ultrasound were independent predictors of PTC recurrence regardless of concurrent LT. PMID: 24954314 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - June 28, 2014 Category: Universities & Medical Training Authors: Kim HG, Kim EK, Han KH, Kim H, Kwak JY Tags: Yonsei Med J Source Type: research

mRNA-SEQ REVEALS NOVEL MOLECULAR MECHANISMS AND A ROBUST FINGERPRINT IN GRAVES' DISEASE.
Conclusions: These data reveal an active immune defense system in Graves' disease which involves novel molecular mechanisms in its pathogenesis and development. PMID: 24971664 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - June 27, 2014 Category: Endocrinology Authors: Yin X, Sachidanandam R, Morshed S, Latif R, Shi R, Davies TF Tags: J Clin Endocrinol Metab Source Type: research

Current therapeutic prospectives in the functional rehabilitation of vocal fold paralysis after thyroidectomy: CO laser aritenoidectomy
A frequent complication of thyroid surgery is laryngeal nerve palsy with transitory or permanent deficiency of cordal motility. Peripheral mono-or bilateral palsy in these cases may either occur, in adduction or abduction, and be complete or not complete. Bilateral vocal cords paralysis cause a persistent dyspnoic symptomatology with worsening during physical exercise or flogistic episodes of the upper airway: true vocal cords adduction, in median or paramedian position reduce the glottic space and increases respiratory resistances. (Source: International Journal of Surgery)
Source: International Journal of Surgery - June 27, 2014 Category: Surgery Authors: Domenico Testa, Germano Guerra, Pasquale Gianluca Landolfo, Michele Nunziata, Giovanni Conzo, Massimo Mesolella, Gaetano Motta Source Type: research

Prophylactic thyroidectomy: Who needs it, when, and why
The most common hereditary thyroid cancer is medullary thyroid cancer, which can be associated with MEN 2A, MEN 2B, or FMTC. In these patients, prophylactic thyroidectomy is recommended; timing of surgery is dependent on the specific RET mutation. Prophylactic thyroidectomy should include total thyroidectomy and accompanying central compartment neck dissection should be done for patients at high risk for micro‐metastatic disease only. Surgery should be performed at tertiary care institutions by high‐volume thyroid surgeons. J. Surg. Oncol. © 2014 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology)
Source: Journal of Surgical Oncology - June 25, 2014 Category: Cancer & Oncology Authors: Tracy S. Wang, Adwoa Opoku‐Boateng, Sanziana A. Roman, Julie Ann Sosa Tags: Review Article Source Type: research

Sutureless thyroidectomy
(Source: International Journal of Surgery)
Source: International Journal of Surgery - June 25, 2014 Category: Surgery Authors: Roberto Ruggiero, Adelmo Gubitosi, Giovanni Conzo, Simona Gili, Alfonso Bosco, Raffaele Pirozzi, Cosma Cosenza, Gianluca Rossetti, Landino Fei, Giovanni Docimo, Ludovico Docimo Source Type: research

Early biomarkers of hypocalcemia following total thyroidectomy
(Source: International Journal of Surgery)
Source: International Journal of Surgery - June 24, 2014 Category: Surgery Authors: A. Bove, R.M. Di Renzo, G. Palone, V. D'Addetta, R. Percario, P. Panaccio, G. Bongarzoni Source Type: research

Coexistence of Papillary Thyroid Cancer and Hashimoto Thyroiditis in Children: Report of 3 Cases
This report documents 3 pediatric papillary thyroid carcinoma cases with associated Hashimoto thyroiditis. In all 3 cases, hypoechoic nodules accompanied by multiple echogenic spots were noted on sonography of the thyroid. Hashimoto thyroiditis was suspected on the basis of positive thyroid autoantibody test results and pathologic examinations of thyroidectomy specimens, which revealed chronic thyroiditis with lymphocytic infiltration as the background of papillary thyroid carcinoma development. The potential for papillary carcinoma development warrants close follow-up, and meticulous sonographic examinations must be perfo...
Source: Journal of Ultrasound in Medicine - June 23, 2014 Category: Radiology Authors: Koibuchi, H., Omoto, K., Fukushima, N., Toyotsuji, T., Taniguchi, N., Kawano, M. Tags: Case Series Source Type: research

The safety of the Harmonic FOCUS in open thyroidectomy: A prospective, randomized study comparing the Harmonic FOCUS and traditional suture ligation (knot and tie) technique
(Source: International Journal of Surgery)
Source: International Journal of Surgery - June 23, 2014 Category: Surgery Authors: Antonio Zanghì, Andrea Cavallaro, Maria Di Vita, Francesco Cardì, Paolo Di Mattia, Gaetano Piccolo, Giuseppina Barbera, Mario Urso, Alessandro Cappellani Source Type: research

Diagnostic Accuracy and Interobserver Agreement of Quasistatic Ultrasound Elastography in the Diagnosis of Thyroid Nodules.
Conclusion: QUE provides accurate quantitative evaluation of thyroid nodules with low interobserver variability. PMID: 24955842 [PubMed - as supplied by publisher] (Source: Ultraschall in der Medizin)
Source: Ultraschall in der Medizin - June 23, 2014 Category: Radiology Authors: Cantisani V, Lodise P, Di Rocco G, Grazhdani H, Giannotti D, Patrizi G, Medvedyeva E, Olive M, Fioravanti C, Giacomelli L, Chiesa C, Redler A, Catalano C, D'Ambrosio F, Ricci P Tags: Ultraschall Med Source Type: research

Relationship between postoperative venous thromboembolism and hemorrhage in patients undergoing total thyroidectomy without preoperative prophylaxis
(Source: International Journal of Surgery)
Source: International Journal of Surgery - June 21, 2014 Category: Surgery Authors: Paolo Limongelli, Salvatore Tolone, Adelmo Gubitosi, Gianmattia del Genio, Giuseppina Casalino, Vincenzo Amoroso, Landino Fei, Giampaolo Jannelli, Luigi Brusciano, Giovanni Docimo, Ludovico Docimo Source Type: research

Is it possible to predict the need for sternotomy in patients undergoing thyroidectomy with retrosternal extension?
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was ‘in patients undergoing thyroidectomy for retrosternal goitre, what factors predict sternotomy?’ Altogether 165 papers were found as a result of the reported search, of which only 3 prospective studies, 1 review paper and 2 retrospective studies represented the best evidence to answer the clinical question. The authors, journals, date and country of publication, patient group studied, study type, relevant outcomes and results of the papers are tabulated. We conclude that a combination of preopera...
Source: Interactive CardioVascular and Thoracic Surgery - June 18, 2014 Category: Cardiovascular & Thoracic Surgery Authors: McKenzie, G. A. G., Rook, W. Tags: Adult Cardiac Source Type: research

A Single Parathyroid Hormone Level Obtained 4 hours after Total Thyroidectomy Predicts the Need for Postoperative Calcium Supplementation
(Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - June 18, 2014 Category: Surgery Authors: Azadeh A. Carr, Tina W. Yen, Gilbert G. Fareau, Ashley K. Cayo, Sarah M. Misustin, Douglas B. Evans, Tracy S. Wang Source Type: research

A Rapid and Accurate Technique for the Identification of the Recurrent Laryngeal Nerve.
CONCLUSION: Using the third ring as guidance, our inferior-superior technique offers an extra benefit in identifying the RLN safely and quickly, as compared to the conventional inferior approach. PMID: 24944276 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 18, 2014 Category: ENT & OMF Authors: Liu SC, Chou YF, Su WF Tags: Ann Otol Rhinol Laryngol Source Type: research