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Fine needle aspiration of secondary synovial sarcoma of the thyroid gland
We present a case of secondary SS of the thyroid originally diagnosed as medullary carcinoma on fine needle aspiration (FNA). A 41‐year‐old man presented with several weeks of dysphonia and a left thyroid mass. FNA of the thyroid nodule showed a cellular smear composed of loosely cohesive oval to spindle‐shaped cells with irregular nuclear borders, finely granular chromatin, and inconspicuous nucleoli. The patient was diagnosed with medullary carcinoma and underwent a total thyroidectomy. Intro‐operatively, the mass was found to arise from the tracheoesophageal groove with spread to the left thyroid. Microscopic ex...
Source: Diagnostic Cytopathology - August 26, 2015 Category: Pathology Authors: Diana Murro, Jamie Macagba Slade, Sahr Syed, Paolo Gattuso Tags: Brief Report Source Type: research

Axillary lymph nodes metastasis in a patient with recurrent papillary thyroid cancer: a case report
Conclusions Axillary lymph node enlargement in a patient with papillary thyroid cancer should be considered metastatic from thyroid until proved otherwise. Careful thorough examination of patients with recurrent thyroid cancer is essential to address any unusual metastasis. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - August 26, 2015 Category: Journals (General) Source Type: research

Endovascular Retrieval of Surgical Sponge within Pulmonary Artery
A 56-year-old man with a history of papillary thyroid carcinoma who previously had undergone total thyroidectomy developed recurrent, poorly differentiated thyroid carcinoma for which he underwent repeat resection and neck dissection. The operation was notable for inadvertent entry into and repair of the right subclavian vein during dissection of the base of the neck. At the conclusion of the procedure, a sponge (Peanut Dissector Sponge; Fabco, New London, Connecticut) was noted to be missing. A postoperative chest radiograph showed the location of the sponge in the chest (arrowhead in Fig 1), specifically in the right pul...
Source: Journal of Vascular and Interventional Radiology : JVIR - August 25, 2015 Category: Radiology Authors: Ron C. Gaba, Ari B. Rubenfeld, Sean P. Zivin, James T. Bui Tags: Extreme IR Source Type: research

Missed Initial Diagnosis of Malignant Struma Ovarii Containing Follicular Thyroid Carcinoma: Metastatic Pulmonary Recurrence 17 yr After Ovariectomy
Distant metastasis of rare malignant struma ovarii (MSO) has been reported for cases associated with papillary thyroid cancer but few with follicular thyroid cancer. A 38-yr-old woman with struma ovarii that was initially diagnosed as “benign” presented with pulmonary metastasis and coughing 17 yr later. The lungs lesions were confirmed to be follicular thyroid cancer by biopsy. Rereview of the initial surgical ovary specimens confirmed the condition to be MSO with follicular thyroid cancer. The patient was treated with total thyroidectomy, which showed no thyroid malignancy, followed by 131I (iodine-131) treatments. D...
Source: International Journal of Gynecological Pathology - August 20, 2015 Category: Pathology Tags: Pathology of the Upper Genital Tract: Case Reports Source Type: research

Spindle epithelial tumor with thymus-like differentiation (SETTLE): clinical-pathological features, differential pathological diagnosis and therapy
Abstract Spindle epithelial tumor with thymus-like differentiation (SETTLE) is a very rare tumor of the thyroid gland. An algorithm for the diagnosis and treatment of SETTLE has yet to be established. The aim of this study was to identify all case reports of SETTLE and to compare the clinical-pathological features and therapy of the cases identified. We performed a PubMed search for case reports of SETTLE in English published up to November 2014 in which “SETTLE” and “Spindle epithelial tumor with thymus-like differentiation” were keywords. We identified 35 articles for a total of 42 cases. We found that S...
Source: Endocrine - August 20, 2015 Category: Endocrinology Source Type: research

Predictive factors for difficult robotic thyroidectomy using the bilateral axillo‐breast approach
ConclusionMale sex was the only predictive factor for difficult robotic thyroidectomy using BABA. Further evaluations should be performed to ascertain additional factors associated with difficult robotic thyroidectomy. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 (Source: Head and Neck)
Source: Head and Neck - August 20, 2015 Category: ENT & OMF Authors: Hee Yong Kwak, Hoon Yub Kim, Hye Yoon Lee, Seung Pil Jung, Sang Uk Woo, Gil Soo Son, Jae Bok Lee, Jeoung Won Bae Tags: Original Article Source Type: research

Metformin Is Associated with a Favorable Outcome in Diabetic Patients with Cervical Lymph Node Metastasis of Differentiated Thyroid Cancer
Conclusions: Metformin treatment is associated with low recurrence in diabetic patients with cervical LN metastasis of DTC.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - August 19, 2015 Category: Endocrinology Source Type: research

Comparison of Secondary and Primary Thyroid Cancers: Patient Characteristics and Postoperative Outcomes : A Cross-Sectional Analysis of Patients with Primary and Secondary Thyroid Cancers.
CONCLUSIONS: Secondary thyroid cancer is associated with a higher risk of perioperative complications and higher cost and distinct demographic profile. Patients managed by higher-volume surgeons were less likely to experience disadvantageous outcomes. PMID: 26282905 [PubMed - as supplied by publisher] (Source: Ann Oncol)
Source: Ann Oncol - August 18, 2015 Category: Cancer & Oncology Authors: Al-Qurayshi Z, Mohamed H, Bhatia P, Srivastav S, Aslam R, Kandil E Tags: Ann Surg Oncol Source Type: research

Comparison of histopathological features and prognosis of classical and follicular variant papillary thyroid carcinoma
Conclusion FVPTC is a common subtype of PTC and has a higher rate of multicentricity with bilobar involvement. Although aggressive histopathologic features, such as thyroid capsule invasion, extrathyroidal extension, and lymph node metastasis, are significantly more frequent in CPTC than in FVPTC, the long-term outcome is similar in both subtypes after appropriate initial surgery and postoperative RAI ablation treatment. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - August 17, 2015 Category: Endocrinology Source Type: research

Cost‐effectiveness analysis of papillary thyroid cancer surveillance
CONCLUSIONSThe cost to detect a recurrence in a low‐risk patient is more than 6 and 7 times greater than the cost for intermediate‐ and high‐risk PTC patients. It is difficult to justify this allocation of resources to the surveillance of low‐risk patients. Surveillance strategies for the low‐risk group should, therefore, be restructured. Cancer 2015. © 2015 American Cancer Society. (Source: Cancer)
Source: Cancer - August 17, 2015 Category: Cancer & Oncology Authors: Laura Y. Wang, Benjamin R. Roman, Jocelyn C. Migliacci, Frank L. Palmer, R. Michael Tuttle, Ashok R. Shaha, Jatin P. Shah, Snehal G. Patel, Ian Ganly Tags: Original Article Source Type: research

Predictive Value of Estimated Tumor Volume Measured by Ultrasonography for Occult Central Lymph Node Metastasis in Papillary Thyroid Carcinoma
This study was performed to investigate the predictive value of estimated tumor volume measured by ultrasonography for occult central neck metastasis (OCNM) of PTC. A total of 264 patients with clinically node-negative PTC on ultrasonography and computed tomography who underwent total thyroidectomy in conjunction with at least ipsilateral prophylactic central neck dissection were enrolled in this study. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - August 17, 2015 Category: Radiology Authors: Ki Nam Park, Kyung Yoon Kang, Hyun Sook Hong, Han-Shin Jeong, Seung Won Lee Tags: Original Contribution Source Type: research

Anaplastic Carcinoma of The Thyroid in A 12-Year Old Girl
We report a case of a 12 year old who presented with a large neck mass. She underwent a total thyroidectomy with right modified radical neck dissection. The pathology revealed papillary cancer of the thyroid with a large anaplastic component. She underwent a total thyroidectomy and modified radical neck dissection. Postoperatively, she was treated with a customized regimen of chemotherapy and radiation. She is disease free three years after diagnosis. (Source: Journal of Pediatric Surgery Case Reports)
Source: Journal of Pediatric Surgery Case Reports - August 16, 2015 Category: Surgery Source Type: research

Surgical and Pathological Changes after Radiofrequency Ablation of Thyroid Nodules.
Conclusions. RFA is effective for the treatment of Thy2 nodules, but it should not be recommended as first-line therapy for the treatment of Thy3 nodules (irrespective of their mutational status), as it delays surgery in case of malignancy. Moreover, it is unknown whether RFA might promote residual tumor progression or neoplastic progression of Thy3 lesions. Nevertheless, here we show for the first time that one session of RFA does not affect subsequent thyroid surgery and/or histological diagnosis. PMID: 26265914 [PubMed] (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - August 14, 2015 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Comparison of ultrasonography features and malignancy rate of toxic and nontoxic autonomous nodules: a preliminary study
Conclusion US features and malignancy potential of nontoxic autonomous nodules resemble toxic autonomous nodules. Lower diameter suggests that they can represent a preliminary stage of toxic ones and have potential of toxicity when get bigger in size. There is still a considerable risk of malignancy risk in autonomous nodules whether toxic or not. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - August 14, 2015 Category: Nuclear Medicine Source Type: research

Thyroid swellings in the art of the Italian Renaissance
Conclusions Even if the function and the role of the thyroid were discovered only after thyroidectomy was started to be performed, at the beginning of the 19th century, artists of the Italian Renaissance had the intuition that thyroid swellings were related to specific psychological conditions. Artistic intuition and sensibility often comes before scientific demonstration, and it should be a guide for science development. (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - August 14, 2015 Category: Surgery Source Type: research

Development of Thyroid-Associated Ophthalmopathy in Patients Who Underwent Total Thyroidectomy.
CONCLUSION: TAO rarely develops after total thyroidectomy, and the mechanism of TAO occurrence is unclear. However, most patients showed abnormalities in thyroid function and TSH receptor autoantibodies. PMID: 26256985 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - August 13, 2015 Category: Universities & Medical Training Authors: Jang SY, Lee KH, Oh JR, Kim BY, Yoon JS Tags: Yonsei Med J Source Type: research

BRAF V600E mutation: Differential impact on central lymph node metastasis by tumor size in papillary thyroid carcinoma
ConclusionProphylactic central neck dissection could be considered in 2.0 to 4.0 cm PTC with positive BRAF mutation. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 (Source: Head and Neck)
Source: Head and Neck - August 13, 2015 Category: ENT & OMF Authors: Seo Ki Kim, Jun Ho Lee, Jung‐Woo Woo, Inhye Park, Jun‐Ho Choe, Jung‐Han Kim, Jee Soo Kim Tags: Original Article Source Type: research

Institution‐specific risk of papillary thyroid carcinoma in atypia/follicular lesion of undetermined significance
ConclusionMalignancy rates in AUS/FLUS vary by institution from 6% to 46%. Given the subjective nature of thyroid cytopathology and interpretation of the BSRTC categories, guidelines should encourage the use of institution‐specific data on malignancy risk in treatment decisions. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 (Source: Head and Neck)
Source: Head and Neck - August 13, 2015 Category: ENT & OMF Authors: Jonathan M. Bernstein, Manish Shah, Christina MacMillan, Jeremy L. Freeman Tags: Original Article Source Type: research

Tumor Genotype Determines Phenotype and Disease-related Outcomes in Thyroid Cancer: A Study of 1510 Patients
Conclusions: In this large study of prospective mutation testing in unselected patients with TC, molecular signature was associated with distinctive phenotypes including cancers, with higher risks of both distant metastasis and early recurrence. Preoperative genotype provides valuable prognostic data to appropriately inform surgery. (Source: Annals of Surgery)
Source: Annals of Surgery - August 12, 2015 Category: Surgery Tags: Papers of the 135th ASA Annual Meeting Source Type: research

Primary papillary carcinoma in thyroglossal cysts. Case reports and literature review.
Abstract The thyroglossal cyst can exceptionally appear as a primary cyst carcinoma. We discuss a series of 6 adult patients, assessed for long-lasting asymptomatic suprahyoid or lateral-to-larynx mass. The images showed a heterogeneous mass invading adjacent soft tissues. Fine needle aspiration biopsy did not contribute to diagnosis. We performed a Sistrunk procedure in all cases, 3 combined with total thyroidectomy and 1 with neck dissection. The postoperative course was favourable. No additional treatment was required, without evidence of recurrence in follow-up. The management is controversial due to the limite...
Source: Acta Otorrinolaringologica Espanola - August 12, 2015 Category: ENT & OMF Authors: Chala A, Álvarez A, Sanabria Á, Gaitán A Tags: Acta Otorrinolaringol Esp Source Type: research

Outpatient Thyroid Surgery in a Low-Surgical Volume Hospital
Conclusion Outpatient thyroid surgery can be performed safely in a low-surgical volume center. Reasons for a longer stay include clinical as well as social factors. (Source: World Journal of Surgery)
Source: World Journal of Surgery - August 11, 2015 Category: Surgery Source Type: research

Factors Predictive of Emergency Department Visits and Hospitalization Following Thyroidectomy and Parathyroidectomy.
CONCLUSIONS: Targeted strategies for transitions of care for patients with postoperative hypocalcemia may help to reduce ED visits and hospitalization after thyroidectomy and parathyroidectomy. PMID: 26259757 [PubMed - as supplied by publisher] (Source: Ann Oncol)
Source: Ann Oncol - August 11, 2015 Category: Cancer & Oncology Authors: FitzGerald RA, Sehgal AR, Nichols JA, McHenry CR Tags: Ann Surg Oncol Source Type: research

Cancer incidence and mortality in patients treated with RAI or thyroidectomy for hyperthyroidism - a nation-wide cohort study with a long-term follow-up.
CONCLUSIONS: In this cohort of Finnish patients with hyperthyroidism treated with thyroidectomy or RAI, the overall risk of cancer was not increased, although an increased risk of gastric and respiratory tract cancers was seen in hyperthyroid patients. Based on this large-scale, long term follow-up study, the increased cancer risk in hyperthyroid patients is attributable to hyperthyroidism and shared risk factors, not the treatment modality. PMID: 26262435 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - August 11, 2015 Category: Endocrinology Authors: Essi R, Saara M, Pia J, Heini H, Rauni S, Matti V, Anssi A Tags: J Clin Endocrinol Metab Source Type: research

The Benefits and Risks of Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma: Prospective Cohort Study.
Conclusions. Patients treated with TT plus CND had a higher rate of complications with similar recurrence rate. We believe that CND may not be routinely recommended when treating patients with PTC. PMID: 26246805 [PubMed] (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - August 8, 2015 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Treatment options in the young patient with Graves’ disease
This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - August 7, 2015 Category: Endocrinology Authors: Tim Cheetham, Richard Bliss Tags: Requested Review Source Type: research

Total or near-total thyroidectomy versus subtotal thyroidectomy for multinodular non-toxic goitre in adults.
CONCLUSIONS: The body of evidence on TT compared with ST is limited. Goiter recurrence is reduced following TT. The effects on other key outcomes such as re-interventions due to goitre recurrence, adverse events and thyroid cancer incidence are uncertain. New long-term RCTs with additional data such as surgeons level of experience, treatment volume of surgical centres and details on techniques used are needed. PMID: 26252202 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 7, 2015 Category: Journals (General) Authors: Cirocchi R, Trastulli S, Randolph J, Guarino S, Di Rocco G, Arezzo A, D'Andrea V, Santoro A, Barczyñski M, Avenia N Tags: Cochrane Database Syst Rev Source Type: research

Mazabraud’s syndrome and thyroid cancer, a very rare and confusing association: a case report
Conclusion: During the evolution of a malignant disease, Mazabraud’s syndrome, known as the association of intramuscular myxoma with fibrous dysplasia, should be considered in the differential diagnosis of bone metastasis. This is the first report in the literature of Mazabraud’s syndrome occurring in a patient with thyroid cancer. (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - August 6, 2015 Category: Endocrinology Authors: Doina PiciuElena BarbusAndra PiciuBogdan Fetica Source Type: research

Loss of neuromonitoring signal during bilateral thyroidectomy: no systematic change in operative strategy according to a survey of the French Association of Endocrine Surgeons (AFCE)
Conclusions: The majority of surgeons continued the operation contralaterally as originally planned despite a loss of IONM signal at the end of the first side. (Source: BMC Surgery)
Source: BMC Surgery - August 6, 2015 Category: Surgery Authors: Lilly KhamsyPaul ConstanthinSamira SadowskiFrédéric Triponez Source Type: research

Bilateral Truncal Ligation of the Inferior Thyroid Artery during Bilateral Subtotal Thyroidectomy Causes a Decrease in Parathormone without Clinically Manifest Hypoparathyroidism: A Randomized Clinical Trial
Conclusion: BTL of the ITA during subtotal thyroidectomy causes a larger decrease in PTH but does not lead to a significantly higher rate of clinically manifest hypoparathyroidism. BTL of the ITA, age >61 years, and a very small thyroid remnant ( (Source: European Surgical Research)
Source: European Surgical Research - August 5, 2015 Category: Surgery Source Type: research

Clinical Association of Thyroid Stimulating Hormone Receptor Antibody Levels with Disease Severity in the Chronic Inactive Stage of Graves' Orbitopathy.
CONCLUSIONS: In chronic-inactive GO after euthyroid restoration, GO activity score did not associate with serum levels of TRAb or TBII. However, levels of the functional antibody Mc4-TSI did correlate with GO severity. Therefore, the TSI bioassay is a clinically relevant measure of disease severity even in chronic inactive GO. PMID: 26240504 [PubMed - in process] (Source: Korean Journal of Ophthalmology : KJO)
Source: Korean Journal of Ophthalmology : KJO - August 5, 2015 Category: Opthalmology Tags: Korean J Ophthalmol Source Type: research

Usefulness of Magnetic Resonance Sialography for the Evaluation of Radioactive Iodine-Induced Sialadenitis
Conclusions MR sialography images are useful for evaluating RAI sialadenitis, and its findings are in accordance with disease severity. An MR sialographic grading system is suggested to describe the severity of obstructive sialadenitis and SG dysfunction. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 5, 2015 Category: Cancer & Oncology Source Type: research

Identification of occult tumors by whole-specimen mapping in solitary papillary thyroid carcinoma
We undertook this study to estimate an accurate incidence and spread patterns of occult papillary thyroid carcinoma (PTC) in patients with a preoperative diagnosis of solitary PTC by using whole-specimen mapping of all specimens after a total thyroidectomy. Enrolled prospectively in this whole-thyroid mapping study are 82 consecutive patients who underwent a total thyroidectomy under a preoperative diagnosis of solitary PTC. All thyroidectomy specimens were serially sectioned in 2 mm thickness and whole-thyroid mapping was carried out for additional foci of occult PTC. The frequencies of occult lesions detected in the whol...
Source: Endocrine-Related Cancer - August 5, 2015 Category: Endocrinology Authors: Park, S. Y., Jung, Y.-S., Ryu, C. H., Lee, C. Y., Lee, Y. J., Lee, E. K., Kim, S.-K., Kim, T. S., Kim, T. H., Jang, J., Park, D., Dong, S. M., Kang, J.-G., Lee, J. S., Ryu, J. Tags: Research Source Type: research

Metastatic Renal Cell Carcinoma presented with thyroid nodule and Addisonian Crisis ‐ A case report of tumor to tumor metastasis
We report a rare case presented as an enlarging primary thyroid tumor which turns out to habour metastatic renal cell carcinoma within, which the primary was only identified after thyroidectomy. The pathological features of metastatic disease into a thyroid neoplasm are demonstrated with a brief review of the literature. (Source: Surgical Practice)
Source: Surgical Practice - August 5, 2015 Category: Surgery Authors: Xina Lo, Tsz Kim Tam, Sai Yin Cheung, Heng Tat Leong Tags: Case Report Source Type: research

Is There Justification for Total Thyroidectomy in Low-Risk Papillary Thyroid Carcinoma? A Decision-Analysis Model
Conclusion Based on our decision-analysis model, hemithyroidectomy is the preferred option in low-risk PTC. (Source: World Journal of Surgery)
Source: World Journal of Surgery - August 4, 2015 Category: Surgery Source Type: research

A Gelatin-Thrombin Matrix Topical Hemostatic Agent (Floseal) in Combination With Harmonic Scalpel Is Effective in Patients Undergoing Total Thyroidectomy: A Prospective, Multicenter, Single-Blind, Randomized Controlled Trial.
CONCLUSION: Floseal + HS can be effective at reducing postsurgical drain output and provides a complementary hemostatic approach in patients undergoing total thyroidectomy. PMID: 26243629 [PubMed - as supplied by publisher] (Source: Surgical Innovation)
Source: Surgical Innovation - August 3, 2015 Category: Surgery Authors: Docimo G, Tolone S, Conzo G, Limongelli P, Del Genio G, Parmeggiani D, De Palma M, Lupone G, Avenia N, Lucchini R, Monacelli M, Gulotta G, Scerrino G, Pasquali D, Bellastella G, Esposito K, De Bellis A, Pezzolla A, Ruggiero R, Docimo L Tags: Surg Innov Source Type: research

Sperm DNA fragmentation after radioiodine treatment for differentiated thyroid cancer
Conclusions: Treatment with 131 I induces alterations in sperm chromatin as well as in sperm parameters a short time (3 months) after a first dose of 131 I with persistence of sperm alterations until 12 months after a second dose. Sperm banking should be recommended before treatment. (Source: BioMed Central)
Source: BioMed Central - August 2, 2015 Category: Journals (General) Authors: Camille Esquerré-LamareFrançois IsusNathalie MoinardLouis Bujan Source Type: research

Post-thyroidectomy complications. The role of the device: Bipolar vs Ultrasonic device Collection of data from 1846 Consecutive Patients Undergoing Thyroidectomy
Conclusions This multicenter study acknowledges the value of the ultrasonic device as a protective factor only for RLN palsy, confirming nodal dissection as a risk factor for postoperative hypocalcemia and vocal folds disorders Teaser This multicenter study acknowledges the value of the ultrasonic device as a protective factor only for RLN palsy, confirming nodal dissection as a risk factor for postoperative hypocalcemia and vocal folds disorders (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - August 2, 2015 Category: Surgery Source Type: research

Sperm DNA fragmentation after radioiodine treatment for differentiated thyroid cancer
Conclusions Treatment with 131I induces alterations in sperm chromatin as well as in sperm parameters a short time (3 months) after a first dose of 131I with persistence of sperm alterations until 12 months after a second dose. Sperm banking should be recommended before treatment. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - August 2, 2015 Category: Urology & Nephrology Source Type: research

Abstract 3829: DNA methylation profile in papillary thyroid cancer according to BRAF (V600E) mutation
Conclusion: This study point out putative drivers in PTC according to BRAF mutation revealing epigenetic mechanisms that contributes with cell proliferation and aggressiveness in thyroid carcinoma.Citation Format: Caroline Moraes Beltrami, Mariana Bisarro dos Reis, Mateus Camargo Barros-Filho, Fabio Albuquerque Marchi, Hellen Kuasne, Srikant Ambatipudi, Zdenko Herceg, Luiz Paulo Kowalski, Silvia Regina Rogatto. DNA methylation profile in papillary thyroid cancer according to BRAF (V600E) mutation. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philad...
Source: Cancer Research - August 2, 2015 Category: Cancer & Oncology Authors: Beltrami, C. M., dos Reis, M. B., Barros-Filho, M. C., Marchi, F. A., Kuasne, H., Ambatipudi, S., Herceg, Z., Kowalski, L. P., Rogatto, S. R. Tags: Molecular and Cellular Biology Source Type: research

Bilateral Areolar Approach Endoscopic Thyroidectomy for Low-risk Papillary Thyroid Carcinoma: Review of 137 Cases in a Single Institute: Erratum
No abstract available (Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques)
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - August 1, 2015 Category: Surgery Tags: Errata Source Type: research

Thyroid Paraganglioma.
Abstract Thyroid paragangliomas are rare tumors that arise from the inferior laryngeal paraganglia. Most patients are female and present with an asymptomatic thyroid nodule. Histologically, the tumor is composed of cells arranged in a well-defined nest (zellballen) pattern surrounded by a thin fibrovascular stroma. It is a diagnostic pitfall and is occasionally misdiagnosed as follicular neoplasm, medullary thyroid carcinoma, intrathyroid parathyroid proliferation, and especially secondary neuroendocrine tumors. Immunohistochemical stains (cytokeratin, parathyroid hormone, thyroid transcription factor 1, tyrosine h...
Source: Archives of Pathology and Laboratory Medicine - August 1, 2015 Category: Laboratory Medicine Authors: Lee SM, Policarpio-Nicolas ML Tags: Arch Pathol Lab Med Source Type: research

58-Year-Old Woman With Melena
A 58-year-old woman presented to the emergency department with a 3-day history of passing dark, tarry stools. Her medical history was notable for symptomatic hemophilia A carrier state, gastroesophageal reflux disease, internal hemorrhoids, papillary thyroid cancer treated with thyroidectomy and radioactive iodine for nodal metastasis with secondary hypothyroidism, and obesity with a recent intentional 22.5-kg weight loss. She reported a 3-day history of passing black, tarry stools, averaging 3 stools per day. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - August 1, 2015 Category: Internal Medicine Authors: Thomas G. Cotter, Badr Al-Bawardy, Conor G. Loftus Tags: Residents’ clinic Source Type: research

Rare Pulmonary Metastasis From Thyroid Mucosa-Associated Lymphoid Tissue Lymphoma.
Abstract Primary pulmonary lymphomas constitute up to 1% of all pulmonary malignancies. Patients with mucosa-associated lymphoid tissue (MALT) lymphoma represent approximately 90% of patients with primary pulmonary lymphoma. Most pulmonary MALT lymphomas are primary tumors. Pulmonary metastasis is extremely rare. A 65-year-old woman was diagnosed with a thyroid MALT lymphoma in 2008 and underwent total thyroidectomy, followed by chemotherapy. After 5 years of follow-up, she referred to our hospital with an abnormal shadow on a chest roentgenogram. She underwent video-assisted thoracoscopic surgery and was diagnos...
Source: The Annals of Thoracic Surgery - August 1, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Satoh K, Morita T, Fumimoto S, Tsuji H, Ichihashi Y, Ochi K, Hanaoka N, Okada Y, Katsumata T Tags: Ann Thorac Surg Source Type: research

Impact of coexistent thyroiditis on clinical outcome in papillary thyroid carcinoma with high preoperative serum antithyroglobulin antibody: a retrospective cohort study
ConclusionResidual/recurrent tumor rate was lower in PTC patients with coexistent CLT than in those without CLT.This article is protected by copyright. All rights reserved. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - August 1, 2015 Category: ENT & OMF Authors: H‐Y Nam, H.Y Lee, G.C Park Tags: Original Manuscript Source Type: research

Endotracheal Tube Size and Postthyroidectomy Vocal Outcomes
This randomized clinical trial of patients undergoing elective thyroidectomy found no evidence that smaller endotracheal tube size has an effect on postoperative vocal outcomes, incidence of laryngeal trauma, or pain scores. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - August 1, 2015 Category: ENT & OMF Source Type: research

Recurrent Laryngeal Nerve Identification in Thyroidectomy by Intra‐operative Staining with Methylene Blue in Forty Six Patients
This article is protected by copyright. All rights reserved. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - July 31, 2015 Category: ENT & OMF Authors: Ahmad Abdel Fattah Nofal, Mohammad Waheed El‐Anwar Tags: Our Experience Source Type: research

Post-thyroidectomy complications. The role of the device: Bipolar vs Ultrasonic device Collection of data from 1846 Consecutive Patients Undergoing Thyroidectomy
This multicenter study acknowledges the value of the ultrasonic device as a protective factor only for RLN palsy, confirming nodal dissection as a risk factor for postoperative hypocalcemia and vocal folds disorders (Source: American Journal of Surgery)
Source: American Journal of Surgery - July 31, 2015 Category: Surgery Authors: Maurizio De Palma, Ludovico Rosato, Fabiana Zingone, Giulio Orlando, Antonio Antonino, Mario Vitale, Alessandro Puzziello Source Type: research

Hypothyroidism minimizes the effects of acute hepatic failure caused by endoplasmic reticulum stress and redox environment alterations in rats.
Abstract The aim of this study was to investigate if a protective effect from hypothyroidism in acute liver failure resulted from reduced endoplasmic reticulum stress and changes to the redox environment. Twenty male Sprague-Dawley rats were divided in four groups: (1) euthyroid (sham surgery), (2) hypothyroid, (3) euthyroid (sham surgery)+thioacetamide and (4) hypothyroid+thioacetamide. Hypothyroidism was confirmed two weeks after thyroidectomy, and thioacetamide (TAA) (400mg/kg, ip) was administrated to the appropriate groups for three days with supportive therapy. Grades of encephalopathy in all animals were det...
Source: Acta Histochemica - July 31, 2015 Category: Biochemistry Authors: Blas-Valdivia V, Cano-Europa E, Martinez-Perez Y, Lezama-Palacios R, Franco-Colin M, Ortiz-Butron R Tags: Acta Histochem Source Type: research

Thyroidectomy without lateral neck dissection for papillary thyroid carcinoma with lateral neck lymph node metastases and negative intraoperative frozen section
ConclusionTotal thyroidectomy with subsequent lateral neck dissection is not necessary in patients with PTC who are diagnosed with lateral neck metastasis according to their permanent pathology report but have negative intraoperative frozen section findings. © 2014 Wiley Periodicals, Inc. Head Neck, 2015 (Source: Head and Neck)
Source: Head and Neck - July 29, 2015 Category: ENT & OMF Authors: Seok‐Mo Kim, Hyeung Kyoo Kim, Kuk‐Jin Kim, Ho Jin Chang, Bup‐Woo Kim, Yong Sang Lee, Hang‐Seok Chang, Cheong Soo Park Tags: Original Article Source Type: research

B cell-activating factor (baff) and baff receptor expression in autoimmune and non autoimmune thyroid diseases.
In this study, we report that BAFF and BAFF-R are expressed in the thyrocytes derived from patients with either AITD or MNG, in addition to the expected expression of BAFF and its receptor in the infiltrating immune cells of GD and HT. These findings suggest a possible involvement of BAFF and its receptors in the pathophysiology of AITD. PMID: 26214745 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - July 28, 2015 Category: Endocrinology Tags: Thyroid Source Type: research