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This page shows you the latest news and research items in this category.

Systematic evaluation of salivary gland damage following I-131 therapy in differentiated thyroid cancer patients by quantitative scintigraphy and clinical follow-up
Conclusion: Although the side effects associated with radioiodine treatment were apparent, they were usually small and temporary. Nevertheless, more consideration should be placed on careful dosing of I-131. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - July 3, 2015 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Microscopic Positive Margins in differentiated thyroid cancer is not an independent predictor of local failure.
Conclusion Patients with resectable, M0 disease that undergo total thyroidectomy have an excellent 5 year LRFS of 99.4%. Microscopic positive margin status was not a significant predictor for local failure after adjusting for ETE or pathological T stage. PMID: 26122000 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - July 2, 2015 Category: Endocrinology Tags: Thyroid Source Type: research

Transient and permanent hypocalcemia after total thyroidectomy: Early predictive factors and long-term follow-up results
Post-thyroidectomy hypocalcemia is among the most common complications of total thyroidectomy. The purpose of this study was to evaluate early predictive factors and long-term changes in intact parathyroid hormone (iPTH) levels in patients with transient and permanent hypocalcemia after total thyroidectomy. (Source: Surgery)
Source: Surgery - July 2, 2015 Category: Surgery Authors: Sung Tae Seo, Jae Won Chang, Jun Jin, Young Chang Lim, Ki-Sang Rha, Bon Seok Koo Tags: Clinical Research Source Type: research

Incidentally Visualization of the Thymus on Whole-Body Iodine Scintigraphy: Report of 2 Cases and Review of the Latest Insights
Abstract: Radioiodine uptake is not commonly seen by the thymus gland. On the contrary, the gland is slowly replaced by fat after puberty. Herein, we present 2 patients with papillary thyroid carcinoma, follicular variant, and cervical lymph node involvement. After total/near-total thyroidectomy, the patients received 131I for ablation therapy. On posttreatment radioiodine scintigraphy, mediastinal 131I uptake was noted that finally was histologically/anatomically diagnosed as thymus gland uptake. It should be borne in mind as a potential cause of false-positive whole-body 131I scintigraphy. (Source: Medicine)
Source: Medicine - July 1, 2015 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Long-Term Follow-Up of the Therapeutic Outcomes for Papillary Thyroid Carcinoma With Distant Metastasis
In conclusion, after a mean follow-up of 10.1 years, the disease-specific mortality rate for PTC with DM was 70.0%. Older patients and male PTC patients with DM need more aggressive treatment. The timing of DM diagnosis did not influence disease-specific mortality. (Source: Medicine)
Source: Medicine - July 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Follicular variant papillary thyroid carcinoma in a pediatric population
ConclusionsIn pediatric patients ≤19 years of age, FVPTCs have intermediate tumor features compared to PTC and FTC, but a similar OS and DSS. All pediatric patients with thyroid cancer require lifelong surveillance. However, FVPTCs >4 cm may warrant closer follow‐up due to an increased risk of death. Pediatr Blood Cancer © 2015 Wiley Periodicals, Inc. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - July 1, 2015 Category: Cancer & Oncology Authors: Jonathan Lerner, Melanie Goldfarb Tags: Research Article Source Type: research

High TPOAb Levels (>1300 IU/mL) Indicate Multifocal PTC in Hashimoto's Thyroiditis Patients and Support Total Thyroidectomy
Conclusion High TPOAb levels (>1300 IU/mL) are definitive indicators of multifocal PTC in HT patients, which may support surgical treatment with total thyroidectomy. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - June 29, 2015 Category: ENT & OMF Authors: Dong, S., Xia, Q., Wu, Y.-J. Tags: Endocrine Surgery Source Type: research

Oropharyngeal Contamination Predisposes to Complications after Neck Dissection: An Analysis of 9462 Patients
Conclusion Using the ACS-NSQIP data set, this study found an increased risk of surgical complications in the setting of contaminated neck dissections. These data should be used for patient risk stratification, informed consent, and to guide further research. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - June 29, 2015 Category: ENT & OMF Authors: Jain, U., Somerville, J., Saha, S., Hackett, N. J., Ver Halen, J. P., Antony, A. K., Samant, S. Tags: Head and Neck Surgery Source Type: research

Evidence‐based management of the thyroid gland during a total laryngectomy
ConclusionsTo our knowledge, this is the largest monocentric series of TGI specimens after a total laryngectomy for laryngeal neoplasms described to date. Focus must be placed on anteroinferior spread, which is likely to invade the cricothyroid membrane, because TGI is part of the extension of extralaryngeal cancer. We propose original experience‐based management of thyroid management during a total laryngectomy to improve the level of accuracy of decision making during the surgical procedure whenever possible. Level of Evidence4 Laryngoscope, 2015 (Source: The Laryngoscope)
Source: The Laryngoscope - June 25, 2015 Category: ENT & OMF Authors: Philippe Gorphe, Aïcha Ben Lakhdar, Yungan Tao, Ingrid Breuskin, François Janot, Stéphane Temam Tags: Head and Neck Source Type: research

Preventive Effect of Human Acellular Dermal Matrix on Post-thyroidectomy Scars and Adhesions: A Randomized, Double-Blinded, Controlled Trial
CONCLUSION: Acellular dermal matrix–assisted implants appear to improve post-thyroidectomy scar and swallowing impairments without delays in operation time. (Source: Dermatologic Surgery)
Source: Dermatologic Surgery - June 25, 2015 Category: Dermatology Tags: Original Article Source Type: research

Radioiodine-remnant ablation in low-risk differentiated thyroid cancer: pros
Abstract Differentiated thyroid carcinomas are typically treated with total thyroidectomy as initial therapy. Subsequent radioactive iodine (RAI) ablation destroys post-surgical thyroid remnants, can additionally provide adjuvant therapy of residual and metastatic thyroid cancers, and enhances the sensitivity and specificity of further diagnostic studies. There is current controversy regarding whether a large number of patients, broadly considered to have “low-risk” disease, should be provided RAI ablation. This is consequent to over-reliance on short-term studies, under-appreciation of the value of RAI remnan...
Source: Endocrine - June 25, 2015 Category: Endocrinology Source Type: research

Role of BRAF V600E mutation as an indicator of the extent of thyroidectomy and lymph node dissection in conventional papillary thyroid carcinoma
The extent of surgery for papillary thyroid carcinoma (PTC) is associated strongly with disease persistence, recurrence, and mortality. It is difficult, however, to determine the optimal extent for surgery. The BRAF mutation is well known for its diagnostic and prognostic value in PTC. Among the variants of PTC, the clinical importance of the BRAF mutation has been associated particularly with conventional PTC. The goal of this study was to clarify the role of the BRAF mutation as a determinant for the operative extent in conventional PTC. (Source: Surgery)
Source: Surgery - June 25, 2015 Category: Surgery Authors: Seo Ki Kim, Jung-Woo Woo, Jun Ho Lee, Inhye Park, Jun-Ho Choe, Jung-Han Kim, Jee Soo Kim Tags: Original Communication Source Type: research

High metabolic tumor volume and total lesion glycolysis are associated with lateral lymph node metastasis in patients with incidentally detected thyroid carcinoma
Conclusions This study has shown for the first time that volume-based PET functional parameters had a significant value for the prediction of lateral LNM in incidentally detected PTC. These results suggest that higher MTV and TLG can be potential new risk factors for preoperative risk stratification. The usefulness of TLG and MTV in preoperative risk stratification in patients with PTC needs to be confirmed in further large studies. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - June 25, 2015 Category: Nuclear Medicine Source Type: research

Prophylactic central lymph node dissection in cN0 patients with papillary thyroid carcinoma: A retrospective study in China.
CONCLUSION: Taken together, in terms of the high incidence rate of CLNM in cN0 PTC patients, we believe that routine prophylactic CLND is optimal for clinically negative PTC patients, during their first treatment, especially for those with risk factors for CLNM. PMID: 26117203 [PubMed - as supplied by publisher] (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - June 24, 2015 Category: Surgery Authors: Xue S, Wang P, Liu J, Li R, Zhang L, Chen G Tags: Asian J Surg Source Type: research

[Vocal cord paralysis after thyroid surgery : Current medicolegal aspects of intraoperative neuromonitoring].
Abstract Intraoperative neuromonitoring (IONM) has been commercially available for approximately 15 years and is highly predictive in thyroid gland surgery concerning either postoperative vocal fold mobility in the case of an intact signal for muscle action electromyogram (EMG, > 99 % right negative) or vocal fold dysfunction in the case of loss of signal (> 70 % right positive). The use of IONM improves the intraoperative identification of recurrent laryngeal nerve function and due to the high predictive value with respect to the expected vocal cord function the result of IONM has to be integrated in...
Source: Der Chirurg - June 23, 2015 Category: Surgery Authors: Dralle H, Schneider R, Lorenz K, Phuong NT, Sekulla C, Machens A Tags: Chirurg Source Type: research

Videoendoscopic Evaluation of Swallowing After Thyroidectomy: 7 and 60 Days
Abstract Deglutition complaints are frequent after thyroidectomy. The purpose of this study was to follow-up on patients with thyroidectomy indication to compare the videoendoscopic evaluation of swallowing on the seventh day (early postoperative, EPO) and on the 60th day after thyroidectomy, (late postoperative, LPO) and to compare patients that evolved with normal laryngeal mobility (NLM) and abnormal laryngeal mobility (ALM). Nasofibroscopic evaluation was performed preoperatively (PRE), on the EPO and LPO. Two groups were compared: ALM and NLM. The majority of people were women, age bracket 46–65, who underw...
Source: Dysphagia - June 19, 2015 Category: Speech Therapy Source Type: research

Variation in cost of total thyroidectomy across the United States, 2007 to 2008
Conclusions More than a quarter of the variation in cost of total thyroidectomy was not explained by patient-, hospital-, or state-level factors. Further research is needed to understand the unexplained residual variation. (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - June 18, 2015 Category: Surgery Source Type: research

A rare case of juvenile hypertension: coexistence of type 2 multiple endocrine neoplasia -related bilateral pheochromocytoma and reninoma in a young patient with ACE gene polymorphism
Conclusion: This unique report describes the association between two rare causes of hypertension in the same patient. Furthermore, the absence of requirement of mineralocorticoid supplementation in spite of bilateral adrenalectomy, represent an uncommon and interest finding. (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - June 18, 2015 Category: Endocrinology Authors: Rosa ParagliolaEttore CapoluongoFrancesco TorinoAngelo MinucciGiulia CanuAlessandro PreteAlfredo PontecorviSalvatore Corsello Source Type: research

Evaluation of the clinical value of carbon nanoparticles as lymph node tracer in differentiated thyroid carcinoma requiring reoperation
Conclusions By tracing the thyroid and cervical regional lymph nodes with carbon nanoparticles, the parathyroid glands can be easily identified and protected to reduce the complications of transient hypoparathyroidism resulting from reoperation for residual or missed DTC. Carbon nanoparticle tracers also facilitate radical resection of lymph nodes at the central and lateral compartments of the neck. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - June 17, 2015 Category: Cancer & Oncology Source Type: research

Value of intra-operative neuromonitoring of the recurrent laryngeal nerve in total thyroidectomy for benign goitre.
CONCLUSION: Intra-operative neuromonitoring does not appear to affect the post-operative recurrent laryngeal nerve palsy rate or to reliably predict post-operative recurrent laryngeal nerve palsy. However, it can accurately predict good nerve function after thyroidectomy. PMID: 26074258 [PubMed - in process] (Source: Journal of Laryngology and Otology)
Source: Journal of Laryngology and Otology - June 16, 2015 Category: ENT & OMF Tags: J Laryngol Otol Source Type: research

Minimally invasive follicular carcinoma: predictors of vascular invasion and impact on patterns of care
Abstract Some studies have reported that minimally invasive follicular carcinoma (MIFC) with vascular invasion is associated with compromised prognosis, leading to an ongoing debate regarding extent of surgery for MIFC. Our goal was to identify predictors of vascular invasion and determine its impact on patterns of care. Adult patients with MIFC were culled from the National Cancer Database, 2010–2011, and segregated according to the presence/absence of capsular or vascular invasion. Variables of interest were examined using Chi-square and student’s t tests. Multivariate analysis was performed with logisti...
Source: Endocrine - June 16, 2015 Category: Endocrinology Source Type: research

Completion thyroidectomy: predicting bilateral disease
Conclusion: In this study, the rate of malignancy in the contralateral lobe was 48 %. Multifocality and presence of an aggressive subtype of papillary thyroid cancer in the initial specimen were found to be more important variables to consider in decision-making regarding completion thyroidectomy than size of the initial tumor alone. (Source: Journal of Otolaryngology - Head and Neck Surgery)
Source: Journal of Otolaryngology - Head and Neck Surgery - June 16, 2015 Category: ENT & OMF Authors: Badr IbrahimVéronique-Isabelle ForestMichael HierAlex MlynarekDerin CaglarRichard Payne Source Type: research

Evaluation of Thyroid Bed Nodules on Ultrasonography after Total Thyroidectomy: Risk for Loco-Regional Recurrence of Thyroid Cancer
Conclusions: Thyroid bed nodules on surveillance ultrasound warrant fine-needle aspiration cytology if they increase in size and number, are persistent and associated with suspicious sonographic features.Eur Thyroid J 2015;4:106-114 (Source: European Thyroid Journal)
Source: European Thyroid Journal - June 15, 2015 Category: Endocrinology Source Type: research

Continuity of care in general surgery resident education
Conclusions The results of this pilot study suggest that continuity of care among general surgery residents is lacking and cannot be entirely accounted for by rotation-specific time constraints. Further research is needed to identify and validate effective curricular strategies for improving opportunities to participate in this essential experience. (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - June 15, 2015 Category: Surgery Source Type: research

Carbon nanoparticle–guided central lymph node dissection in clinically node‐negative patients with papillary thyroid carcinoma
ConclusionCarbon nanoparticles can be applied to more accurately guide the dissection of lymph nodes during thyroidectomy in patients with PTC. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 (Source: Head and Neck)
Source: Head and Neck - June 15, 2015 Category: ENT & OMF Authors: Youzhi Zhu, Xiangjin Chen, Huihao Zhang, Ling Chen, Shujun Zhou, Kunlin Wu, Zongcai Wang, Lingjun Kong, Hezhu Zhuang Tags: Original Article Source Type: research

Long-Term Effect of Surgery in Graves' Disease: 20 Years Experience in a Single Institution.
Authors: Sung TY, Lee YM, Yoon JH, Chung KW, Hong SJ Abstract The present study compared the long-term outcome of subtotal thyroidectomy (ST) to that of total thyroidectomy (TT) in Graves' disease (GD). Patients with GD requiring surgery were divided between two groups: ST and TT. Postoperative thyroid function (PoTF) changes, including hypothyroidism, euthyroidism, and hyperthyroidism, and surgical complications were analyzed 3 months and 2 years after surgery. During the study period, 350 GD patients underwent surgery, of whom 254 underwent ST and 96 underwent TT. In the ST group, the rates of hypothyroidism, eut...
Source: International Journal of Endocrinology - June 14, 2015 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Effect of a Low Iodine Diet vs. Restricted Iodine Diet on Postsurgical Preparation for Radioiodine Ablation Therapy in Thyroid Carcinoma Patients.
CONCLUSION: A 2-week RID can be considered as a type of radioiodine ablation therapy after patients undergo a total thyroidectomy. PMID: 26069126 [PubMed - as supplied by publisher] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - June 13, 2015 Category: Universities & Medical Training Authors: Lim CY, Kim JY, Yoon MJ, Chang HS, Park CS, Chung WY Tags: Yonsei Med J Source Type: research

Comparison of conventional l -thyroxine withdrawal and moderate hypothyroidism in preparation for whole-body 131-I scan and thyroglobulin testing
Conclusions Half-dose L-T4 protocol, compared to conventional L-T4 withdrawal, is associated with less biochemical disorders but no significant clinical advantage. Therefore, the half-dose protocol reaches an adequate TSH target in 48.3 % of patients and is not effective unless basal serum TSH is ≥0.52 μU/ml. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - June 13, 2015 Category: Endocrinology Source Type: research

Determinants of successful ablation and complete remission after total thyroidectomy and 131 I therapy of paediatric differentiated thyroid cancer
Conclusion In our paediatric DTC population prognosis is extremely good with no deaths or recurrences occurring regardless of the number of 131I therapies needed or whether CR was reached. The determinants of CR and successful ablation can be used to optimize the chance of therapy success. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - June 13, 2015 Category: Nuclear Medicine Source Type: research

Determinants of successful ablation and complete remission after total thyroidectomy and (131)I therapy of paediatric differentiated thyroid cancer.
CONCLUSION: In our paediatric DTC population prognosis is extremely good with no deaths or recurrences occurring regardless of the number of (131)I therapies needed or whether CR was reached. The determinants of CR and successful ablation can be used to optimize the chance of therapy success. PMID: 26070546 [PubMed - as supplied by publisher] (Source: Molecular Medicine)
Source: Molecular Medicine - June 13, 2015 Category: Molecular Biology Authors: Verburg FA, Mäder U, Luster M, Hänscheid H, Reiners C Tags: Eur J Nucl Med Mol Imaging Source Type: research

The use of a biologic topical haemostatic agent (Tachosil) for the prevention of postoperative bleeding in patients on antithrombotic therapy undergoing thyroid surgery: A Randomised controlled pilot trial
Anticoagulants and antiplatelet agents are well-known risk factors for post-operative bleeding. The aim of this prospective, randomized pilot study was to evaluate the effectiveness of a topical haemostatic agent, namely TachoSil, for the prevention of postoperative bleeding in patients on antithrombotic therapy undergoing thyroidectomy. Perioperative management and some distinctive aspects of cervical haematomas were also discussed. (Source: International Journal of Surgery)
Source: International Journal of Surgery - June 13, 2015 Category: Surgery Authors: Enrico Erdas, Fabio Medas, Francesco Podda, Silvia Furcas, Giuseppe Pisano, Angelo Nicolosi, Pietro Giorgio Calò Source Type: research

SMAD4 gene promoter mutations in patients with thyroid tumors.
Abstract As a key component of the transforming growth factor beta (TGFB) pathway, which regulates the expression of thyroid-specific genes, tumor suppressor SMAD4 is crucial for thyroid development and function. Aberrant expression of SMAD4 in thyroid tumor tissue was reported and mutations affecting the coding region have been detected, but potential role of mutations in SMAD4 gene regulatory regions remains unexplored. The aim of this study was to analyze SMAD4 gene promoters in thyroid tumors. A total of 76 thyroidectomy specimens were studied, including 42 malignant and 34 benign tumors. The presence of mutati...
Source: Experimental and Molecular Pathology - June 13, 2015 Category: Pathology Authors: Nikolic A, Ristanovic M, Zivaljevic V, Rankov AD, Radojkovic D, Paunovic I Tags: Exp Mol Pathol Source Type: research

Low Recurrence Rates in a Cohort of Differentiated Thyroid Carcinoma Patients: a Referral Center Experience.
CONCLUSIONS: The majority of the DTC patients who were considered to be disease-free after the initial treatment remained with this status at long-term follow-up. This data suggest that less intensive follow-up may apply for these patients. PMID: 26061907 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - June 12, 2015 Category: Endocrinology Tags: Thyroid Source Type: research

Trends in Robotic Thyroid Surgery in the United States from 2009 through 2013.
CONCLUSIONS: From 2009 through early 2011, there was a steady increase in RT volume, especially among high volume institutions. In mid to late 2011, there was a noticeable drop in RT volume, which significantly altered the projected trajectory of the procedure in this country. Despite higher complication rates, lower volume centers perform the majority of RT and are also responsible for recent increases in RT utilization patterns in the US. PMID: 26061477 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - June 12, 2015 Category: Endocrinology Tags: Thyroid Source Type: research

Is preoperative vitamin D deficiency a risk factor for postoperative symptomatic hypocalcemia in thyroid cancer patients undergoing total thyroidectomy plus central compartment neck dissection?
CONCLUSION: VDD is significantly associated with postoperative symptomatic hypocalcemia in thyroid cancer patients undergoing TT plus CCND. VDD was predictive for symptomatic hypocalcemia when patients had postoperative serum iPTH levels <15 pg/ml. Thus, we suggest that preoperative supplementation with oral vitamin D should be considered to minimize postoperative symptomatic hypocalcemia. PMID: 26061175 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - June 12, 2015 Category: Endocrinology Tags: Thyroid Source Type: research

Castleman disease mimicking nodal recurrence of thyroid cancer
Abstract A 54-year-old woman who had undergone total thyroidectomy and radioactive iodine treatment for papillary thyroid cancer presented with elevated stimulated thyroglobulin levels and negative I-131 scan. Ultrasonography revealed suspicious lateral neck lymph nodes, which were FDG-avid. Neck dissection led to a diagnosis of Castleman disease. (Source: Endocrine)
Source: Endocrine - June 9, 2015 Category: Endocrinology Source Type: research

Review of survival rates 20-years after conservative surgery for papillary thyroid carcinoma
Conclusion Because of the rate of 20% of contralateral recurrence after a 20-year follow-up, we suggest modification of the surgical paradigm for total thyroidectomy as an initial therapy. (Source: Brazilian Journal of Otorhinolaryngology)
Source: Brazilian Journal of Otorhinolaryngology - June 9, 2015 Category: ENT & OMF Source Type: research

Management of the thyroid gland during total laryngectomy in patients with laryngeal squamous cell carcinoma
ConclusionRoutine surgical management of the thyroid gland should not be performed, except in cases of subglottic primary lesions, lesions with significant subglottic extension, or transglottic lesions. Despite efforts to preserve the contralateral thyroid lobe in cases of selective lobectomy, these patients often have a high rate of hypothyroidism, and a total thyroidectomy should be considered when involvement of the thyroid gland is suspected. Level of EvidenceN/A. Laryngoscope, 2015 (Source: The Laryngoscope)
Source: The Laryngoscope - June 8, 2015 Category: ENT & OMF Authors: Moustafa Mourad, Masoud Saman, Raja Sawhney, Yadranko Ducic Tags: Head and Neck Source Type: research

Multifocality and bilaterality of papillary thyroid microcarcinoma.
CONCLUSION: In cases of PTMCs, the incidence of multifocal tumors is high. However, additional tumor foci are too small to be diagnosed preoperatively, especially under the recent guidelines on radiologic screening tests for papillary thyroid carcinoma. Multifocal PTMCs have high risk of bilateral tumors, necessitating more extensive surgery or more thorough follow-up. PMID: 26045918 [PubMed] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - June 7, 2015 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

The effect of total thyroidectomy on the speech production.
CONCLUSION: Patients with thyroidectomy have some difficulty of pitch control and consonant articulation during speaking. VOT is also one of the meaningful acoustic parameters and provide a reference for comparing acoustic measures before and after thyroidectomy. PMID: 26045915 [PubMed] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - June 7, 2015 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Nationwide multicenter survey for current status of endoscopic thyroidectomy in Korea.
CONCLUSION: Our results shed light on the general consensus of opinions about endoscopic thyroidectomy, such as the advantages, disadvantages, complications, limitations, and even its future role. PMID: 26045914 [PubMed] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - June 7, 2015 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Multiple thyroid nodules in the lung: metastasis or ectopia?
Conclusions: This is a rare thyroid disease with malignant behavior but no pathological evidence. Careful diagnosis and postoprative follow-up should be carried out whenever such nodules are encountered in clinical practice.Virtual slidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1255194331453728. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 6, 2015 Category: Pathology Authors: Henghui ChengLili YangJing XiongJian PengQiurong Ruan Source Type: research

Risk factors for neck hematoma after thyroid or parathyroid surgery: ten-year analysis of the nationwide inpatient sample database.
CONCLUSION: We identified demographic and clinical factors associated with increased risk of neck hematoma after thyroid or parathyroid surgery. PMID: 25663203 [PubMed - in process] (Source: The Permanente journal)
Source: The Permanente journal - June 4, 2015 Category: Journals (General) Tags: Perm J Source Type: research

Histopathological findings in goiter: A review of 624 thyroidectomies.
CONCLUSIONS: MNG is common and FVPC is the common thyroid cancer seen in females. The overall frequency of thyroid cancer is 11%. Follicular adenoma and FVPC appears to be associated with long standing MNG of iodine deficiency. PMID: 25789588 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - June 4, 2015 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

[Learning curve for transaxillary endoscopic thyroidectomy].
PMID: 26041149 [PubMed - as supplied by publisher] (Source: Der Chirurg)
Source: Der Chirurg - June 4, 2015 Category: Surgery Authors: Dralle H, Thanh PN Tags: Chirurg Source Type: research

Predictors of incomplete response to therapy among Filipino patients with papillary thyroid cancer in a tertiary hospital
Conclusion A significant fraction of PTC patients experienced incomplete response to therapy. Our data suggest that male gender, lateral or mediastinal lymph node involvement, class III extent of disease by De Groot and multifocality with concurrent tumour or tumours more than 1 cm are major predictors of incomplete response. Not all predictors of recurrence and mortality are consistent predictors of treatment response which may be equally important in a disease with low mortality but significant morbidity like PTC. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - June 3, 2015 Category: Endocrinology Source Type: research

The potential relationship between hashimoto's thyroiditis and BRAFV600E Mutation status in papillary thyroid cancer
Conclusions: HT was negatively associated with BRAFV600E mutation, extrathyroidal extension, and LNM. In addition, HT was related to less LNM and extrathyroidal extension in PTCs with BRAFV600E mutation. Therefore, HT is a potentially protective factor in PTC. This article is protected by copyright. All rights reserved. (Source: Head and Neck)
Source: Head and Neck - June 3, 2015 Category: ENT & OMF Authors: Rui‐chao Zeng, Lang‐ping Jin, En‐dong Chen, Si‐yang Dong, Ye‐feng Cai, Guan‐li Huang, Quan Li, Chun Jin, Xiao‐hua Zhang, Ou‐chen Wang Tags: Original Article Source Type: research

Role of RAI in the management of incidental N1a disease in papillary thyroid cancer
ConclusionThere is no difference in the 5 year central compartment nodal recurrence‐free survival in patients treated without RAI compared to those who received RAI treatment.This article is protected by copyright. All rights reserved. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - June 3, 2015 Category: Endocrinology Authors: Laura Y. Wang, Frank L. Palmer, Jocelyn C. Migliacci, Iain J. Nixon, Ashok R. Shaha, Jatin P. Shah, R. Michael Tuttle, Snehal G. Patel, Ian Ganly Tags: Original Article Source Type: research

Comparing Dose Rates Near a Radioactive Patient Evaluated Using Various Source Models: Point, Line, Cylinder, and Anthropomorphic Phantoms
This study investigated radiation exposures from nuclear medicine patients by systematically comparing the dose rates calculated using various source models, ranging from simplified point, line, and cylinder sources to high-quality anthropomorphic phantoms. Three widely used radionuclides, 99mTc, 18F, and 131I, were considered in these source models with uniform or organ-dependent distributions. Conducting Monte Carlo simulations with anthropomorphic phantoms is a realistic but time-consuming approach. The point source model is simple but too conservative, overestimating dose rates by approximately a factor of 2 at a dista...
Source: Health Physics - June 1, 2015 Category: Radiology Tags: Papers Source Type: research

Robotic Thyroidectomy: Is it a Futile Surgical Approach?
No abstract available (Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques)
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - June 1, 2015 Category: Surgery Tags: Letters to the Editor Source Type: research