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Cardiovascular morbidity and mortality in surgically treated hyperthyroidism – a nation‐wide cohort study with a long‐term follow‐up
ConclusionsThe present study shows that hyperthyroidism increases the risk of hospitalization due to CVDs and the risk is sustained up to two decades after effective surgical treatment. However, there was no excess CVD mortality in the middle‐aged patient cohort studied. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - December 5, 2013 Category: Endocrinology Authors: Essi Ryödi, Jorma Salmi, Pia Jaatinen, Heini Huhtala, Rauni Saaristo, Matti Välimäki, Anssi Auvinen, Saara Metso Tags: Original Article Source Type: research
Continuous vagal IONM prevents RLN paralysis by revealing initial EMG changes of impending neuropraxic injury: A prospective, multicenter study
Conclusions: Continuous vagal monitoring is safe and provides real‐time RLN evaluation during surgical maneuvers. Combined‐events and LOS, both easily identifiable intraoperatively, are related to the development of VCP. A combined‐event represents a largely reversible electrophysiologic change when the associated surgical maneuver is aborted. If allowed to continue, it can advance to LOS (which is typically significantly less reversible) and to postoperative VCP. Continuous vagal monitoring has utility in identifying real‐time adverse concordant amplitude and latency changes (combined‐events) which can prompt mo...
Source: The Laryngoscope - December 4, 2013 Category: ENT & OMF Authors: E Phelan, R Schneider, K Lorenz, H Dralle, D Kamani, A Potenza, N Sritharan, J Shin, G Randolph Tags: Original Report Source Type: research
Comparison of (18)F-fluoride PET/CT, (18)F-FDG PET/CT, and bone scintigraphy (planar and SPECT) in detection of bone metastases of differentiated thyroid cancer: a pilot study.
Conclusions:The sensitivity and accuracy of (18)F-fluoride PET/CT for the detection of bone metastases of DTC are significantly higher than that of (99m)Tc bone scintigraphy (planar). However, the sensitivity and accuracy of (99m)Tc bone scintigraphy (planar) are improved near to those of (18)F-fluoride PET/CT when SPECT is added to a planar scan. The sensitivity of (18)F-FDG PET/CT is significantly lower than that of (18)F-fluoride PET/CT or (99m)Tc bone scintigraphy (SPECT).Advances in knowledge:This paper has demonstrated first the high efficacy of (18)F-fluoride PET/CT for the detection of bone metastases of DTC. P...
Source: The British Journal of Radiology - December 2, 2013 Category: Radiology Authors: Ota N, Kato K, Iwano S, Ito S, Abe S, Fujita N, Yamashiro K, Yamamoto S, Naganawa S Tags: Br J Radiol Source Type: research
Anti‐thyroid antibodies as a predictor of thyroid cancer
ConclusionPatients with positive thyroid antibodies have a greater risk of malignancy in those with benign FNAC. We recommend routine thyroid antibody assessment in addition to FNAC as part of the assessment of thyroid nodules. (Source: ANZ Journal of Surgery)
Source: ANZ Journal of Surgery - December 1, 2013 Category: Surgery Authors: Sze Ling Wong, Simon Grodski, Meei J. Yeung, Jonathan W. Serpell Tags: Original Article Source Type: research
Risk factors and clinical indication of metastasis to lymph nodes posterior to right recurrent laryngeal nerve in papillary thyroid carcinoma: A single‐center study in China
ConclusionLymph node PRRLN should be routinely explored during CCD because of the possibility of only involvement in PTC. Factors of tumors larger than 1 cm, multifocality, and extrathyroidal extension were independent predictors of lymph node PRRLN metastasis in right‐sided PTC, and suggested the clinical indications of lymph node PRRLN dissection. © 2013 Wiley Periodicals, Inc. Head Neck , 2013 (Source: Head and Neck)
Source: Head and Neck - November 27, 2013 Category: ENT & OMF Authors: Zhang Pinyi, Zhang Bin, Bu Jianlong, Liu Yao, Zhang Weifeng Tags: Original Article Source Type: research
Monitoring differentiated thyroid cancer patients with negative serum thyroglobulin. Diagnostic implication of TSH-stimulated antithyroglobulin antibody.
Conclusion: The change in serum TgAb level after TSH stimulation is different between the RD and ND groups, and thus, it may be used as a surrogate diagnostic marker for DTC when the serum Tg is negative and TgAb is positive. PMID: 24276613 [PubMed - as supplied by publisher] (Source: Nuklearmedizin)
Source: Nuklearmedizin - November 26, 2013 Category: Radiology Authors: Nam HY, Paeng JC, Chung JK, Kang KW, Cheon GJ, Kim Y, Park DJ, Park YJ, Min HS, Lee DS Tags: Nuklearmedizin Source Type: research
The Effect of Extent of Surgery and Number of Lymph Node Metastases on Overall Survival in Patients with Medullary Thyroid Cancer.
Conclusions:The number of lymph node metastases should be incorporated into MTC staging. Extent of surgery in patients with MTC should be tailored to tumor size and distant metastases. PMID: 24276457 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - November 25, 2013 Category: Endocrinology Authors: Esfandiari NH, Hughes DT, Yin H, Banerjee M, Haymart MR Tags: J Clin Endocrinol Metab Source Type: research
Determination of the Optimal Time Interval for Repeat Evaluation following a Benign Thyroid Nodule Aspiration.
Conclusions:An initially benign FNA confers negligable mortality risk during long-term follow up despite a low risk of identifying several such nodules as thyroid cancer. As such malignancies appear adequately treated despite detection at a mean 4.5yrs following falsely benign cytology, these data support a recommendation for repeat thyroid nodule evaluation 2-4yrs after initial benign FNA. PMID: 24276452 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - November 25, 2013 Category: Endocrinology Authors: Nou E, Kwong N, Alexander LK, Cibas ES, Marqusee E, Alexander EK Tags: J Clin Endocrinol Metab Source Type: research
A randomized controlled trial for the use of Thymus Honey in decreasing Salivary Gland Damage following Radioiodine Therapy for Thyroid cancer: research protocol
DiscussionThe recommended intervention protocol is expected to improve the comprehensive management of salivary gland‐related side effects induced by the radioiodine treatment in people diagnosed with thyroid cancer. Through the methodological approach chosen, the ideal intervention protocol in terms of the time to initiate the intervention and the frequency of the intervention to acquire optimal results in minimizing salivary glands damage will be tested. (Source: Journal of Advanced Nursing)
Source: Journal of Advanced Nursing - November 21, 2013 Category: Nursing Authors: Andreas Charalambous, Savvas Frangos, Michalis Talias Tags: Research Protocol Source Type: research
Abstract Thyroid cancer is rapidly increasing in incidence, but the mortality rate remains flat. Debate has arisen over the need to detect or treat most thyroid cancers early, given their favorable natural history. The appropriate extent of surgery for thyroid cancer is also controversial: some researchers advocate partial and others total thyroidectomy; some advocate prophylactic central cervical lymph node dissection, whereas others only rarely recommend lymphadenectomy. Although radioactive iodine is effective, its appropriate use and dosage remain controversial. In addition, molecular analysis of thyroid cancer...
Source: Annual Review of Medicine - November 20, 2013 Category: Journals (General) Authors: Carling T, Udelsman R Tags: Annu Rev Med Source Type: research
Effect of reoperation on outcomes in papillary thyroid cancer
Background: The influence of lymph node recurrences of papillary thyroid carcinoma (PTC) on overall prognosis is uncertain. We performed a population-based, longitudinal analysis to evaluate the impact of reoperation on mortality.Methods: Patients who underwent initial operation for PTC >1 cm were abstracted from the California Cancer Registry database (1999−2008). Reoperation was defined as any lymph node dissection after total or near-total thyroidectomy.Results: Of the 11,986 patients included in the study, 222 (1.9%) underwent one or more reoperations. The median time to reoperation was 8.7 months, with 58.6% and 83....
Source: Surgery - November 19, 2013 Category: Surgery Authors: Stephanie Young, Avital Harari, Stephanie Smooke-Praw, Philip H.G. Ituarte, Michael W. Yeh Tags: American Association of Endocrine Surgeons Source Type: research
A novel optical approach to intraoperative detection of parathyroid glands
Conclusion: NIR fluorescence spectroscopy can detect intraoperatively the parathyroid regardless of tissue pathology. The signal may be caused by calcium-sensing receptors present in the parathyroid. The signal strength and consistency indicates the simplicity and effectiveness of this method. Its implementation may limit operative time, decrease costs, and improve operative success rates. (Source: Surgery)
Source: Surgery - November 19, 2013 Category: Surgery Authors: Melanie A. McWade, Constantine Paras, Lisa M. White, John E. Phay, Anita Mahadevan-Jansen, James T. Broome Tags: American Association of Endocrine Surgeons Source Type: research
The relationship between chronic lymphocytic thyroiditis and central neck lymph node metastasis in North American patients with papillary thyroid carcinoma
Conclusion: Female patients of all ages with CLT and small PTCs have the least incidence of CNM. (Source: Surgery)
Source: Surgery - November 19, 2013 Category: Surgery Authors: Sebastian M. Jara, Kathryn A. Carson, Sara I. Pai, Nishant Agrawal, Jeremy D. Richmon, Jason D. Prescott, Alan Dackiw, Martha A. Zeiger, Justin A. Bishop, Ralph P. Tufano Tags: American Association of Endocrine Surgeons Source Type: research
Cost analysis of thyroid lobectomy and intraoperative frozen section versus total thyroidectomy in patients with a cytologic diagnosis of “suspicious for papillary thyroid cancer”
Conclusion: In our model, initial total thyroidectomy is cost-effective for patients with a single thyroid nodule suspicious for PTC on FNA. Our results strongly support total thyroidectomy for initial treatment; thyroid lobectomy is preferred only when complications reach unacceptable levels. (Source: Surgery)
Source: Surgery - November 19, 2013 Category: Surgery Authors: Andrew J. Leiker, Tina W. Yen, Kevin Cheung, Douglas B. Evans, Tracy S. Wang Tags: American Association of Endocrine Surgeons Source Type: research
The impact of surgical volume on patient outcomes following thyroid surgery
Conclusion: Surgery for Graves disease is associated with a higher risk for complications when performed by less experienced surgeons. This finding should prompt recommendations for increasing surgical specialization and referrals to high-volume surgeons in the management of Graves disease. (Source: Surgery)
Source: Surgery - November 19, 2013 Category: Surgery Authors: Emad Kandil, Salem I. Noureldine, Ali Abbas, Ralph P. Tufano Tags: American Association of Endocrine Surgeons Source Type: research
Observation of clinically negative central compartment lymph nodes in papillary thyroid carcinoma
Conclusion: Our results suggest that properly selected patients can be managed safely with observation of the central neck rather than prophylactic central neck dissection, which has a higher complication rate. (Source: Surgery)
Source: Surgery - November 19, 2013 Category: Surgery Authors: Iain J. Nixon, Ian Ganly, Snehal G. Patel, Luc G. Morris, Frank L. Palmer, Dorothy Thomas, R. Michael Tuttle, Jatin P. Shah, Ashok R. Shaha Tags: American Association of Endocrine Surgeons Source Type: research
A new tool: The same dilemma
The need for routine pre- and postoperative assessment of vocal cord function in patients undergoing thyroidectomy remains a question of strongly held conviction and conflicting data. Some experienced endocrine surgeons argue passionately in favor of routine laryngoscopy (either indirect or fiberoptic), whereas others advocate a more selective approach. In a recent survey of American Association of Endocrine Surgeons members, the majority of respondents, most of whom are high-volume surgeons in academic practices, did not feel that routine preoperative laryngoscopy was appropriate in all patients. Rather, they perform voc...
Source: Surgery - November 19, 2013 Category: Surgery Authors: Keith S. Heller Tags: American Association of Endocrine Surgeons Source Type: research
Surgical outcomes of robotic thyroid surgery using a double incision gasless transaxillary approach: Analysis of 400 cases treated by the same surgeon
ConclusionRobotic thyroid surgery is technically safe and may be a surgical option for patients with well‐differentiated thyroid cancer. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)
Source: Head and Neck - November 18, 2013 Category: ENT & OMF Authors: Yu‐Mi Lee, Onvox Yi, Tae‐Yon Sung, Ki‐Wook Chung, Jong Ho Yoon, Suck Joon Hong Tags: Original Article Source Type: research
Left-shifted relation between calcium and parathyroid hormone in Graves' Disease.
Conclusion:Patients with GD demonstrate dysregulation of the calcium homeostasis by several parameters. GD patients have lower postoperative S-calcium compared to patients with MNG, lower calcium/PTH setpoint and a significantly increased release of PTH to hypocalcemic stimulus compared to controls. The CiCa clamp response in GD patients with normal 25-OH-vitamin D3 levels mimics that of obese patients in which vitamin D insufficiency has been proposed as an underlying cause. PMID: 24248181 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - November 18, 2013 Category: Endocrinology Authors: Annerbo M, Hultin H, Stålberg P, Hellman P Tags: J Clin Endocrinol Metab Source Type: research
Successful nasal intubation with a laryngeal nerve monitoring tube using bronchoscopy in a patient with plunging goiter: a case report
Conclusion: Our experience suggests that nasal intubation can be safely performed by using a nerve integrity monitoring tube with the help of fiberoptic bronchoscopy. (Source: BMC Research Notes)
Source: BMC Research Notes - November 15, 2013 Category: Research Authors: Savino SpadaroManuela D¿AgataMarco VerriRiccardo RagazziCarlo Volta Source Type: research
[Minimally invasive video-assisted thyroidectomy : Establishment in a thyroid center.]
CONCLUSION: During introduction of the MIVAT procedure a learning effect can be observed which is hallmarked by a decrease in operating time and conversion rate to open surgery. Moreover, no significant differences in terms of main postoperative complications were found so that MIVAT can be considered a safe and feasible technique under the conditions of correct eligibility criteria. PMID: 24218083 [PubMed - as supplied by publisher] (Source: Der Chirurg)
Source: Der Chirurg - November 13, 2013 Category: Surgery Authors: Piniek A, Schuhmann R, Coerper S Tags: Chirurg Source Type: research
Preservation of the inferior thyroidal vein reduces post‐thyroidectomy hypocalcemia
Conclusion: The described surgical method preserves the inferior thyroidal vein and may reduce post‐thyroidectomy hypocalcemia without disturbing the extent of central lymph node harvesting. Preservation of the bilateral inferior thyroidal veins is important for reducing hypocalcemia and promoting faster recovery post‐thyroidectomy. (Source: The Laryngoscope)
Source: The Laryngoscope - November 12, 2013 Category: ENT & OMF Authors: Doh YoungLee, Wonjae Cha, Woo‐Jin Jeong, Soon‐Hyun Ahn Tags: Original Report Source Type: research
Coexistence of Malignant Struma Ovarii and Cervical Papillary Thyroid Carcinoma.
Conclusion:Our findings provided support for synchronous, albeit distinct, primary tumors in the ovary and cervical thyroid. "Field cancerization" and early genomic instability may explain multifocality in all thyroid-type tissue. In this regard, patients with malignant struma ovarii should undergo imaging of their thyroid gland for coexisting disease and thyroidectomy recommended for suspected malignancy or in preparation for radioiodine therapy. PMID: 24217901 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - November 11, 2013 Category: Endocrinology Authors: Leong A, Roche PJ, Paliouras M, Rochon L, Trifiro M, Tamilia M Tags: J Clin Endocrinol Metab Source Type: research
Combination of Surgical Subcision and Intralesional Corticosteroid Injection As a Cost‐Effective and Minimally Invasive Treatment for Postoperative Adhesive Thyroidectomy Scars
ConclusionCombined treatment with surgical subcision and intralesional corticosteroid injection is a cost‐effective and minimally invasive treatment for postoperative adhesive thyroidectomy scars. (Source: Dermatologic Surgery)
Source: Dermatologic Surgery - November 10, 2013 Category: Dermatology Authors: Ji Hye Lee, Tae Hyung Kim, Yong Sang Lee, Hang‐Seok Chang, Cheong Soo Park, Mi Ryung Roh Tags: Original Article Source Type: research
Robotic modified radical neck dissection by bilateral axillary breast approach for papillary thyroid carcinoma with lateral neck metastasis
ConclusionsRobotic MRND using BABA is safe and shows oncologic and postoperative outcomes comparable to those of the open procedure. Head Neck, 2013 (Source: Head and Neck)
Source: Head and Neck - November 8, 2013 Category: ENT & OMF Authors: Byung Seup Kim, Kyung Ho Kang, Sung Jun Park Tags: Research Article Source Type: research
Comparison of surgical completeness between robotic total thyroidectomy versus open thyroidectomy
Conclusion: The surgical completeness of robotic total thyroidectomy by a GUAB/GUB approach is comparable to that of open thyroidectomy if performed by experienced robotic thyroid surgeons in properly selected patients. (Source: The Laryngoscope)
Source: The Laryngoscope - November 7, 2013 Category: ENT & OMF Authors: Kyung Tae, Chang Myeon Song, Yong Bae Ji, Kyung Rae Kim, Ji Young Kim, Yun Young Choi Tags: Original Report Source Type: research
Appropriate Timing for Thyroidectomy Scar Treatment Using a 1,550‐nm Fractional Erbium‐Glass Laser
ConclusionEarly postoperative 1,550‐nm fractional erbium‐glass laser treatment of thyroidectomy scars is more effective than later treatment. (Source: Dermatologic Surgery)
Source: Dermatologic Surgery - November 7, 2013 Category: Dermatology Authors: Kui Young Park, In Young Oh, Seong Jun Seo, Kyung Ho Kang, Sung Jun Park Tags: Original Article Source Type: research
Completion thyroidectomy of well-differentiated thyroid cancer - a prospective, miserandomised study.
CONCLUSIONS: The intraoperative use of a hand-held gamma detector can help to improve the radicality of a completion thyroidectomy procedure after an incomplete primary thyroid resection, but the results of this procedure in the hands of an experienced surgeon are comparable whether or not the gamma detector is used. (Endokrynol Pol 2013; 64 (5): 335-339). PMID: 24186588 [PubMed - in process] (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - November 6, 2013 Category: Endocrinology Authors: Proczko M, Stefaniak T, Sworczak K, Kobiela J, Lachiński AJ, Stepaniak P, Sledziński Z Tags: Endokrynol Pol Source Type: research
Improving and standardising thyroid hormone replacement therapy post thyroid surgery
Aim: To improve thyroid hormone replacement therapy post total thyroidectomy operations. Methods: 2-cycles audit. In the first audit cycle, the records of patients who underwent thyroid surgery over a 10 months period were retrospectively reviewed. The thyroid hormone replacement prescribing was compared to local guidelines for thyroid replacement following radioactive iodine ablation. We subsequently instituted an improved operation notes proforma by introducing a thyroid hormone replacement box to improve communication between the operating surgeon and ward doctors. A prospective re-audit after introducing the intervent...
Source: International Journal of Surgery - November 5, 2013 Category: Surgery Authors: Ali Al-lami, Piyush Jani Tags: Abstracts from the Association of Surgeons in Training Conference Source Type: research
Thyroidectomy Does Not Ease CVD Risk (CME/CE)
(MedPage Today) -- People with hyperthyroidism have an increased risk of cardiovascular disease even after successful surgical treatment, researchers reported. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 1, 2013 Category: Cardiology Source Type: news
Hypocalcemia after total laryngectomy
ConclusionsHypocalcemia is common after total laryngectomy, particularly in the postradiotherapy setting and in patients undergoing bilateral neck dissection. Preservation of one thyroid lobe does not appear to significantly reduce the risk. Level of Evidence4. Laryngoscope, 2013 (Source: The Laryngoscope)
Source: The Laryngoscope - November 1, 2013 Category: ENT & OMF Authors: Naveed Basheeth, Eadaoin O'Cathain, Gerard O'Leary, Patrick Sheahan Tags: Head and Neck Source Type: research
Predictors of early post-operative hypocalcemia after parathyroidectomy for secondary hyperparathyroidism.
Abstract We sought to identify predictors of development of early post-operative hypocalcemia after parathyroidectomy for secondary hyperparathyroidism. The patients were divided into two groups according to their serum calcium (Ca) levels within 24 hours of undergoing para-thyroidectomy: the hypocalcemia group (22 patients) with post-operative serum Ca levels of 2 mmol/L or less, and the normocalcemia group (48 patients), with post-operative serum Ca levels higher than 2 mmol/L. By using multivariate stepwise logistic regression analysis, high pre-operative serum Ca level had the strongest predictive value of deve...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2013 Category: Urology & Nephrology Authors: Hamouda M, Dhia NB, Aloui S, El Mhamedi S, Skhiri H, Elmay M Tags: Saudi J Kidney Dis Transpl Source Type: research
After thyroid cancer, measuring segments of genetic material may help predict and monitor recurrence
A new analysis has found that the presence of short segments of genetic material (known as microRNA) within papillary thyroid cancer tumors suggests a likelihood of recurrence after patients undergo surgery. The study, which is published early online in CANCER, a peer-reviewed journal of the American Cancer Society, also found that elevated blood levels of the genetic material after surgery may indicate a higher possibility of recurrence after thyroidectomy. MicroRNAs are copies of very short segments of genetic material that modulate gene expression... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 30, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
Incidental thyroid nodules in patients with primary hyperparathyroidism
Conclusions: The rate of clinically significant thyroid malignancy in patients undergoing surgical treatment of primary hyperparathyroidism was 1.8%. Head Neck, 2013 (Source: Head and Neck)
Source: Head and Neck - October 30, 2013 Category: ENT & OMF Authors: David J. Phillips, David I. Kutler, William I. Kuhel Tags: Research Article Source Type: research
Recurrence of thyroid cancer 'could be predicted' with microRNAs
New research has found that measuring sections of genetic material within papillary thyroid cancer tumors could predict the chance of recurrence following surgery. This is according to a study published in the journal Cancer. Researchers from Australia say they also discovered that elevated blood levels of this genetic material, known as microRNAs, could also indicate an increased chance of recurrence after thyroidectomy - the surgical removal of all or part of the thyroid gland... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 28, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
Measuring segments of genetic material may help predict and monitor recurrence after thyroid cancer
(Wiley) A new analysis has found that the presence of short segments of genetic material (known as microRNA) within papillary thyroid cancer tumors suggests a likelihood of recurrence after patients undergo surgery. The study, which is published early online in CANCER, a peer-reviewed journal of the American Cancer Society, also found that elevated blood levels of the genetic material after surgery may indicate a higher possibility of recurrence after thyroidectomy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 28, 2013 Category: Global & Universal Source Type: news
MicroRNA‐222 and MicroRNA‐146b are tissue and circulating biomarkers of recurrent papillary thyroid cancer
CONCLUSIONSThis study demonstrated that tumor levels of miR‐222 and miR‐146b are associated with PTC recurrence and that miR‐222 and miR‐146b levels in the circulation correspond to the presence of PTC. The potential of these miRNAs as tumor biomarkers to improve patient stratification according to the risk of recurrence and as circulating biomarkers for PTC surveillance warrants further study. Cancer 2013. © 2013 American Cancer Society. (Source: Cancer)
Source: Cancer - October 28, 2013 Category: Cancer & Oncology Authors: James C. Lee, Jing Ting Zhao, Roderick J. Clifton‐Bligh, Anthony Gill, Justin S. Gundara, Julian C. Ip, Anthony Glover, Mark S. Sywak, Leigh W. Delbridge, Bruce G. Robinson, Stanley B. Sidhu Tags: Original Article Source Type: research
A multi-institutional international study of risk factors for hematoma after thyroidectomy
Conclusion: A significant number of patients with a postoperative hematoma present >6 hours after thyroidectomy. Hematoma is associated with patients who have a drain or hemostatic agent, have Graves' disease, are actively using antiplatelet/anticoagulation medications or have large thyroids. Surgeons should consider these factors when individualizing patient disposition after thyroidectomy. (Source: Surgery)
Source: Surgery - October 28, 2013 Category: Surgery Authors: Michael J. Campbell, Kelly L. McCoy, Wen T. Shen, Sally E. Carty, Carrie C. Lubitz, Jacob Moalem, Matthew Nehs, Tammy Holm, David Y. Greenblatt, Danielle Press, Xiaoxi Feng, Allan E. Siperstein, Elliot Mitmaker, Cassandre Benay, Roger Tabah, Sarah C. Oltm Tags: American Association of Endocrine Surgeons Source Type: research
Decreasing the dose of radioiodine for remnant ablation does not increase structural recurrence rates in papillary thyroid carcinoma
Conclusion: Decreasing the dose of RAI at initial ablation for patients with pT1–pT3 PTC does not seem to be associated with an increased risk of structural cancer recurrence. (Source: Surgery)
Source: Surgery - October 28, 2013 Category: Surgery Authors: Schelto Kruijff, Ahmed M. Aniss, Paul Chen, Stan B. Sidhu, Leigh W. Delbridge, Bruce Robinson, Roderick J. Clifton-Bligh, Paul Roach, Anthony J. Gill, Diane Learoyd, Mark S. Sywak Tags: American Association of Endocrine Surgeons Source Type: research
Relationship between Onset of Hypocalcemic Symptoms and the Recovery Time from Transient Hypocalcemia after Total Thyroidectomy
Conclusions: Recovery time can be predicted by time of onset of hypocalcemic symptoms and signs. Earlier onset leads to longer recovery times. Head Neck, 2013 (Source: Head and Neck)
Source: Head and Neck - October 25, 2013 Category: ENT & OMF Authors: Yong Sang Lee, Hang Seok Chang, Woong Youn Chung, Kee‐Hyun Nam, Cheong Soo Park Tags: Original Article Source Type: research
BRAF V600 co‐testing is technically feasible in conventional thyroid fine needle aspiration (FNA) cytology smears and can reduce the need for completion thyroidectomy
ConclusionBased on this methodology and other published results for the BRAF mutation, we believe that it is now feasible and cost effective for the UK NHS to BRAF co‐test all Thy4/Bethesda Class V thyroid FNAs, as the additional cost of BRAF testing will still be much less than the cost of submitting all Thy4 (Bethesda Class V) patients to a partial and then a later completion thyroidectomy. (Source: Cytopathology)
Source: Cytopathology - October 25, 2013 Category: Pathology Authors: D. N. Poller, S. Glaysher Tags: Original Article Source Type: research
Routine prophylactic central neck dissection for low-risk papillary thyroid cancer: A cost-effectiveness analysis
Conclusion: Routine pCND for low-risk PTC is not cost-effective unless the recurrence rate is greater than 10.3%. Application of pCND should be individualized based on risk of recurrence and added complications. (Source: Surgery)
Source: Surgery - October 25, 2013 Category: Surgery Authors: Kyle Zanocco, Dina Elaraj, Cord Sturgeon Tags: American Association of Endocrine Surgeons Source Type: research
TSH Suppression: More Harm Than Good After Cancer Surgery?
SAN JUAN (MedPage Today) -- Suppressing thyroid-stimulating hormone (TSH) after thyroidectomy for low-risk cancer increases the risk of osteoporosis in women without cutting back on cancer recurrence, researchers reported here. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - October 19, 2013 Category: Endocrinology Source Type: news
Three-dimensional minimally invasive video-assisted thyroidectomy: preliminary report
Three-dimensional (3D) minimally invasive video-assisted thyroidectomy (MIVAT) was carried out with a 4-mm, 3D 0-degree stereoscopic endoscope. The procedure was applied on 3 patients who underwent total thyroidectomy and data were prospectively collected. Operative time for total thyroidectomy ranged from 72 to 90 minutes. Neither intra-nor post-operative complications were reported during the study.The surgical team noticed a good perception of depth and easy recognising of anatomic structures, especially concerning the upper and lower vascular pedicle, the parathyroids, the superior and inferior laryngeal nerves. Prelim...
Source: Journal of Experimental and Clinical Cancer Research - October 18, 2013 Category: Cancer & Oncology Authors: Giuseppe MercantePaolo BattagliaValentina MancioccoGiovanni CristalliRaul PelliniGiuseppe Spriano Source Type: research
A Novel Method for Creating Working Space During Endoscopic Thyroidectomy via Bilateral Areolar Approach
Journal of Laparoendoscopic & Advanced Surgical Techniques , Vol. 0, No. 0. (Source: Journal of Laparoendoscopic)
Source: Journal of Laparoendoscopic - October 17, 2013 Category: Surgery Tags: article Source Type: research
Familial history of non‐medullary thyroid cancer is an independent prognostic factor for tumor recurrence in younger patients with conventional papillary thyroid carcinoma
ConclusionFNMTC may be considered as a separate clinical entity with a higher rate of recurrence and worse DFS than its sporadic counterpart. Furthermore, familial history of NMTC is an independent risk factor for recurrence, especially in younger patients with conventional PTC. J. Surg. Oncol. © 2013 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology)
Source: Journal of Surgical Oncology - October 16, 2013 Category: Cancer & Oncology Authors: Yu‐Mi Lee, Jong Ho Yoon, Onvox Yi, Tae‐Yon Sung, Ki‐Wook Chung, Won Bae Kim, Suck Joon Hong Tags: Research Article Source Type: research
Both Hypothyroidism and Hyperthyroidism Increase Atrial Fibrillation Inducibility in Rats [Original Articles]
Conclusions— Both hypothyroidism and hyperthyroidism lead to increased AF vulnerability in a rat thyroidectomy model. Our results stress that normal thyroid hormone levels are required to maintain normal cardiac electrophysiology and to prevent cardiac arrhythmias and AF. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - October 15, 2013 Category: Cardiology Authors: Zhang, Y., Dedkov, E. I., Teplitsky, D., Weltman, N. Y., Pol, C. J., Rajagopalan, V., Lee, B., Gerdes, A. M. Tags: Electrophysiology, Animal models of human disease, Arrythmias-basic studies Original Articles Source Type: research
Thyroid surgical practices shaping thyroid cancer incidence in North-Eastern Italy.
CONCLUSION: Data from the Veneto Region suggest that the increase in PTMC is due to several factors: increased preoperative diagnosis, total gland removal, extensive histological examination. Moreover, geographical variations in cancer incidence were associated to surgery rates for benign diseases. PMID: 24184200 [PubMed - as supplied by publisher] (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 14, 2013 Category: Drugs & Pharmacology Authors: Rosa Pelizzo M, Rubello D, Bernardi C, Gemo G, Bertazza L, Schievano E, Fedeli U Tags: Biomed Pharmacother Source Type: research
Thermal sealing systems with and without tissue divider for total thyroidectomy
ConclusionThe incorporation of a tissue divider into thermal sealing devices is efficacious and safe, with no compromise in clinical outcome, while providing the added benefit of a significant reduction in operative times. (Source: ANZ Journal of Surgery)
Source: ANZ Journal of Surgery - October 10, 2013 Category: Surgery Authors: Anthony R. Glover, Justin S. Gundara, James C. Lee, Mark S. Sywak, Leigh W. Delbridge, Stan B. Sidhu Tags: Original Article Source Type: research
Perioperative indicators of hypocalcemia in total thyroidectomy: the role of vitamin D and parathyroid hormone
Abstract: Background: Hypocalcemia is a common complication of thyroidectomy. The aim of this study was to identify risk factors for this problem.Methods: This prospective analysis included 111 patients undergoing total or completion thyroidectomy. Preoperative vitamin D levels and postoperative day 1 parathyroid hormone levels were analyzed for their predictive effects on postoperative hypocalcemia.Results: Patients with ionized calcium (Source: American Journal of Surgery)
Source: American Journal of Surgery - October 10, 2013 Category: Surgery Authors: Eric M. Salinger, John T. Moore Tags: Southwestern Surgical Congress Source Type: research