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Does Postthyroidectomy Syndrome Really Exist Following Thyroidectomy? Prospective Comparative Analysis of Open vs. Endoscopic Thyroidectomy.
CONCLUSION: PTS really exists following simple thyroidectomy and are very common for both OPEN and ENDO groups. Most of the parameters improved gradually over time, but some subjective changes persisted 6 months postoperatively. PMID: 25729500 [PubMed] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - March 3, 2015 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Disseminated bone metastases from occult thyroid cancer effectively treated with debulking surgery and a single dosimetry-guided administration of radioiodine
Publication date: March–April 2015 Source:Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 34, Issue 2 Author(s): Elisa Borsò , Giuseppe Boni , Sara Mazzarri , Arturo Cocciaro , Carlo Gambacciani , Antonio C. Traino , Giampiero Manca , Mariano Grosso , Cristian Scatena , Valerio Ortenzi , Riccardo Vannozzi , Maria Cristina Marzola , Domenico Rubello , Giuliano Mariani In this paper we report on a successful management of multiple bone metastases from differentiated thyroid cancer. In 2007, a 75-year-old female patient, previously referred for thyroidectomy for multinodular goiter, und...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - February 28, 2015 Category: Nuclear Medicine Source Type: research

Impact of tumor size on subclinical central lymph node metastasis in papillary thyroid microcarcinoma depends on age
Conclusions: Factors predictive of central LNM in patients with PTMC differed by age. PTMC size was an independent predictor of subclinical central LNM only in patients aged ≥45 years. (Source: World Journal of Surgical Oncology)
Source: World Journal of Surgical Oncology - February 28, 2015 Category: Cancer & Oncology Authors: Ju-Yeon KimEun JungTaejin ParkSang-Ho JeongChi-Young JeongYoung-Tae JuYoung-Joon LeeSoon-Chan HongSang-Kyung ChoiWoo-Song Ha Source Type: research

Improving the functionality of intra-operative nerve monitoring during thyroid surgery: is lidocaine an option?
Abstract Intra-operative nerve monitoring (IONM) is rapidly becoming a standard of care in many institutions across the country. In the absence of neuromuscular blocking agents to facilitate the IONM, the depth of anesthesia required to abolish the laryngo tracheal reflexes often results in profound hemodynamic instability during surgery, necessitating the use of large doses of sympathomimetic amines. The excessive alpha and beta adrenergic effects exhibited by these agents are undesirable in the presence of cardiovascular co-morbidities. Trying to strike a balance frequently results in an unsatisfactory intra-oper...
Source: Clin Med Res - February 27, 2015 Category: Research Authors: Govindarajan R, Shah A, Reddy VS, Parithivel V, Ravikumar S, Livingstone D Tags: J Clin Med Res Source Type: research

Non-contrast-enhanced computed tomography attenuation in the parotid glands before radioiodine therapy for thyroid carcinoma could be a predictor of radiovulnerability
This study aimed to determine a predictive factor for the effect of radioiodine therapy (RIT) on salivary gland dysfunction through a multiple regression analysis. Methods: We retrospectively assessed 40 patients with thyroid carcinoma, including 13 men (age range, 21–80 years) and 27 women (age range, 28–75 years), who underwent total thyroidectomy and were treated with RIT. We used multiple regression analysis to evaluate whether factors such as age, sex, dose number, prescintigraphy grade, computed tomography (CT) attenuation, and CT volume of the salivary glands affected the postscintigraphy grade. Receiver operati...
Source: Nuclear Medicine Communications - February 26, 2015 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The problem of unrecognized acromegaly: surgeries patients undergo prior to diagnosis of acromegaly
Conclusions Acromegaly patients mostly present to internal medicine professionals. Surgeries related to acromegaly complications and symptoms before diagnosis cause a long delay period before diagnosis. Medical staff must be more aware of the clinical aspects of acromegaly. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - February 26, 2015 Category: Endocrinology Source Type: research

Graves’ disease: a review of surgical indications, management, and complications in a cohort of 59 patients
An analysis of 59 patients who underwent total thyroidectomy for the treatment of Graves’ disease over a 6-year period was conducted in order to assess the current indications and identify any specific factors that may influence the patient's decision to opt for surgical treatment. A comparison of outcomes between the current study and a similar one from Hong Kong was also attempted. Patient preference was the most common reason for opting for surgery over radioactive iodine in both studies. Other indications for surgery, such as Graves’ ophthalmopathy, patient refusal for radioactive iodine, large goitre with pressure...
Source: International Journal of Oral and Maxillofacial Surgery - February 25, 2015 Category: ENT & OMF Authors: P. Stathopoulos, S. Gangidi, G. Kotrotsos, D. Cunliffe Tags: Clinical Paper Source Type: research

Severe Vitamin D Deficiency: A Significant Predictor of Early Hypocalcemia after Total Thyroidectomy
Conclusion Postoperative clinical and laboratory hypocalcemia is significantly associated with low levels of serum 25 hydroxyvitamin D. Our findings identify severe vitamin D deficiency (<25 nmol/L) as an independent predictor of postoperative laboratory hypocalcemia. Early identification and management of patients at risk may reduce morbidity and costs. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - February 25, 2015 Category: ENT & OMF Authors: Al-Khatib, T., Althubaiti, A. M., Althubaiti, A., Mosli, H. H., Alwasiah, R. O., Badawood, L. M. Tags: Endocrine Surgery Source Type: research

An engagement factor for caregiver radiation dose assessment with radioiodine treatment
This study aims to suggest ways to better manage thyroid cancer patients treated with high- and low-activity radioiodine (131I) by assessing external radiation doses to family members and caregivers and the level of radiation in the surrounding environment. The radiation doses to caregivers of 33 inpatients (who were quarantined in the hospital for 2–3 d after treatment) and 31 outpatients who received radioiodine treatment after thyroidectomy were measured using passive thermoluminescence dosemeters. In this study, 33 inpatients were administered high-activity (100–200 mCi) 131I, and 31 outpatients were admini...
Source: Radiation Protection Dosimetry - February 25, 2015 Category: Radiology Authors: Lee, H. K., Hong, S. J., Jeong, K. H., Jung, J. W., Kim, S. M., Kang, Y.-H., Han, M. S. Tags: Papers Source Type: research

Surgical anatomy of the ansa cervicalis nerve: which branch to use for laryngeal reinnervation in humans?
Conclusion The common trunk of the SHM and STM is the prime choice for laryngeal reinnervation using AC-RLN non-selective anastomosis. If the main trunk is missing, the branch to the STM can be an attractive candidate. (Source: Surgical and Radiologic Anatomy)
Source: Surgical and Radiologic Anatomy - February 21, 2015 Category: Anatomy Source Type: research

Identification of parathyroid glands: anatomical study and surgical implications
Abstract While performing thyroid surgery, the unintentional lesion of parathyroid glands and laryngeal nerves results in a profound alteration in patient’s quality of life. To minimize thyroid surgery morbidity, the surgeon must have an in-depth knowledge of the thyroid gland morphology and its anatomical relations in the anterior compartment of the neck. This work intended to simulate total thyroidectomies using cadaver parts and isolate fragments that may correspond to parathyroid glands. The thyroid glands and “eventual” parathyroid glands were then submitted to histological study. Ninety-two cadaver pa...
Source: Surgical and Radiologic Anatomy - February 21, 2015 Category: Anatomy Source Type: research

Clinicopathological risk factors and biochemical predictors of safe discharge after total thyroidectomy and central compartment node dissection for thyroid cancer: a prospective study.
Authors: Lee YM, Cho JY, Sung TY, Kim TY, Chung KW, Hong SJ, Yoon JH Abstract To determine the clinicopathological risk factors and reliable biochemical predictors of the development of hypocalcemic symptoms after total thyroidectomy on the basis of serum calcium and intact parathyroid hormone (PTH) levels measured 1 hour after surgery, a prospective study was performed on 817 patients who underwent a total thyroidectomy with central compartment node dissection (CCND) due to well-differentiated thyroid cancer. We evaluated the correlations between hypocalcemic symptom development and clinicopathological factors. An...
Source: International Journal of Endocrinology - February 19, 2015 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Differences in Physicians' and Patients' Perception of Acute Hypothyroid Symptoms Induced by Thyroid Hormone Withdrawal in Thyroid Cancer Patients: A Multicenter Survey in Korea
Conclusions: There was a substantial gap in the perception of hypothyroid symptoms during THW between physicians and patients. Physicians who are aware of the seriousness of hypothyroidism in their patients were more likely to recommend the use of rhTSH for their patients.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - February 19, 2015 Category: Endocrinology Source Type: research

Isolated skeletal muscle metastatic deposit in a patient with micropapillary carcinoma thyroid identified by 18F FDG PET CT
We report the identification of an isolated FDG avid muscle deposit in a treated case of micropapillary carcinoma of the right lobe and widely invasive follicular carcinoma of the left lobe thyroid gland. Patient was found to have an elevated thyroglobulin level with negative iodine scan (TENIS syndrome) on follow up at 6months. An 18F FDG PET CT (18 fluorine-fluorodeoxyglucose positron emission computed tomography) whole body study revealed a solitary FDG avid deltoid muscle deposit which was histopathologically confirmed to be metastatic papillary carcinoma. While follicular carcinoma is known to have distant metastases,...
Source: Journal of the Egyptian National Cancer Institute - February 17, 2015 Category: Cancer & Oncology Source Type: research

Patterns of thyroid hormone levels in pediatric medullary thyroid carcinoma patients on vandetanib therapy
Conclusions: In our cohort of pediatric MTC patients, athyreotic patients with preexisting hypothyroidism developed increased TSH and reduced free T4 during the first few months of treatment with vandetanib, necessitating an increase in LT dosage. Additional patients with normal thyroid function before treatment and intact glands (n = 2) maintained normal thyroid function tests during treatment. Elevated TSH in athyreotic patients may be due to an indirect effect of vandetanib on the metabolism of thyroid hormone, or to altered TSH sensitivity at the pituitary. Proper recognition and management of abnormal thyroid hormone ...
Source: International Journal of Pediatric Endocrinology - February 16, 2015 Category: Endocrinology Authors: Maya LodishAlexandra GkourogianniEthan BornsteinNinet SinaiiElizabeth FoxMeredith ChukLeigh MarcusSrivandana AkshintalaFrank BalisBrigitte WidemannConstantine Stratakis Source Type: research

Isolated skeletal muscle metastatic deposit in a patient with micropapillary carcinoma thyroid identified by 18F FDG PET CT.
We report the identification of an isolated FDG avid muscle deposit in a treated case of micropapillary carcinoma of the right lobe and widely invasive follicular carcinoma of the left lobe thyroid gland. Patient was found to have an elevated thyroglobulin level with negative iodine scan (TENIS syndrome) on follow up at 6months. An 18F FDG PET CT (18 fluorine-fluorodeoxyglucose positron emission computed tomography) whole body study revealed a solitary FDG avid deltoid muscle deposit which was histopathologically confirmed to be metastatic papillary carcinoma. While follicular carcinoma is known to have distant metastases,...
Source: J Egypt Natl Canc In... - February 16, 2015 Category: Cancer & Oncology Authors: Sarma M, Sonik B, Subramanyam P, Shanmuga Sundaram P Tags: J Egypt Natl Canc Inst Source Type: research

Cerebellar mass as a primary presentation of papillary thyroid carcinoma: case report and literature review.
Conclusion Brain metastasis may rarely be the initial presentation of papillary thyroid carcinoma. Solitary brain metastasis can completely be resected with better prognosis. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research

Zhou XC, Hu KQ, Zhang XF, Ye YH, Jiang Y, Pan F, Li XY, Zhou H. Breast cancer metastatic to the bilateral thyroid: a case report. Head Neck Oncol. 2012 Sep 9;4(2):51.
We describe the case of a 41-year-old woman with a history of bilateral breast cancer, presented with elevated serum carbohydrate antigen (CA) 153 level, and ultrasonography revealed the bilateral thyroid lobes and isthmus diffuse distribution of point-like calcifications, no nodules were palpable, total thyroidectomy was performed. A firm diagnosis of metastatic breast carcinoma to the thyroid was established. With this report, we should strengthen the argument that any patient with a thyroid lesion and a history of malignancy should be considered to have a metastasis until proven otherwise, also we conclude that total th...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research

Anzai T, Yokoyama J, Ohba S, Ito S, Fujimaki M, Kojima M, Ikeda K. An important initial diagnosis of a patient with Graves' disease associated with myasthenia gravis, thyroid carcinoma, and thymoma. Head Neck Oncol. 2012 Sep 9;4(2):56.
Conclusion If a patient is diagnosed with Graves’ disease, it is important to check for thyroid carcinoma, mediastinal disease and other autoimmune diseases at the same time. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research

A novel platform for nucleic acid biomarker-based diagnosis of thyroid cancer.
The standard of care for patients with clinically significant thyroid nodules is an ultrasound-guided fine needle aspiration biopsy with cytologic evaluation.  Nearly 20% of patients are found to have indeterminate cytology, requiring surgical thyroidectomy to exclude malignancy; nucleic acid-based biomarkers to improve diagnosis are promising, but there is clearly a need for improved technology to bring these into common clinical practice.  Here we demonstrate the use of a thermoplastic disposable microfluidic chip to extract nucleic acids from thyroid cancer cell lines and thyroid tissue for potential use as a ...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research

Primary sclerosing mucoepidermoid carcinoma of the thyroid: A case report and review of the literature.
Conclusion: Although SMECE is considered to be a relatively slow growing and non-aggressive tumor, occasional metastasis do occur. Physicians should be aware of extended operation, include total thyroidectomy and/or neck node dissection for metastatic lesion of neck node. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research

Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: more aggressive than previously reported
Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) of the thyroid is a rare traditionally “low-grade” tumor that predominantly occurs in women. About 50 cases have been reported in the literature. It arises in a background of Hashimoto’s thyroiditis and is characterized by nests of epidermoid and mucin-secreting cells located within an eosinophil-rich sclerotic stroma. Herein, we outline the clinicopathologic and immunohistochemical characteristics of six cases of thyroid SMECE. All tumors were detected in women (age 36-90 years; average 59) and all patients underwent total thyroidectomies. (Source: Human Pathology)
Source: Human Pathology - February 12, 2015 Category: Pathology Authors: Gabriela M. Quiroga-Garza, Jeong Hyeon Lee, Adel El-Naggar, Jennifer O. Black, Mojgan Amrikachi, Qihui J. Zhai, Alberto G. Ayala, Jae Y. Ro Tags: Original contribution Source Type: research

The Utility of Neck Ultrasound and Sestamibi Scans in Patients with Secondary and Tertiary Hyperparathyroidism
Conclusion US and MIBI offer little benefit in localizing ectopic glands and rarely change the conduct of a standard four-gland exploration. Although there was a benefit of US in the assessment of thyroid nodules, in only 8.7 % of patients was sestamibi of benefit in identifying ectopic glands. (Source: World Journal of Surgery)
Source: World Journal of Surgery - February 11, 2015 Category: Surgery Source Type: research

Prospective Randomized Controlled Trial on the Use of Flexible Reinforced Laryngeal Mask Airway (LMA) during Total Thyroidectomy: Effects on Postoperative Laryngopharyngeal Symptoms: Reply
(Source: World Journal of Surgery)
Source: World Journal of Surgery - February 11, 2015 Category: Surgery Source Type: research

Early Severe Fetal Graves Disease in a Mother After Thyroid Ablation and Thyroidectomy.
CONCLUSION:: It is possible for fetal Graves disease to develop as early as 18 weeks of gestation, and women who have had thyroid ablation and postsurgical hypothyroidism remain at risk for this serious pregnancy complication. PMID: 25710616 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - February 11, 2015 Category: OBGYN Authors: Donnelly MA, Wood C, Casey B, Hobbins J, Barbour LA Tags: Obstet Gynecol Source Type: research

BRAF mutation in fine‐needle aspiration specimens as a potential predictor for persistence/recurrence in patients with classical papillary thyroid carcinoma larger than 10 mm at a BRAF mutation prevalent area
ConclusionThe BRAF mutation was significantly associated with persistence/recurrence and a potential predictor in patients with classical PTC >10 mm at a BRAF mutation prevalent area. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 (Source: Head and Neck)
Source: Head and Neck - February 9, 2015 Category: ENT & OMF Authors: Hee Jung Moon, Eun‐Kyung Kim, Woong Youn Chung, Dong Yeob Shin, Jin Young Kwak Tags: Original Article Source Type: research

131I Abnormal Uptake by the Thyroid Bed From Zuckerkandl Tubercle Diagnosis by 131I SPECT/CT
Abstract: After thyroid remnant ablation following total thyroidectomy for thyroid cancer, 131I SPECT/CT revealed 131I uptake, regarded as thyroid bed uptake on planar images, in the anterior cervical region. On SPECT/CT, the 131I uptake focus appeared at the esophagus, suggesting esophageal invasion. No esophageal invasion had been recognized intraoperatively, and no residual uptake was detected by 131I scintigraphy evaluating therapeutic effects 3 months after ablation. Preoperative CT revealed a retrotracheal space portion extending from the normal thyroid with the same density, suggesting Zuckerkandl tubercle. Abnormal...
Source: Clinical Nuclear Medicine - February 7, 2015 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Multifocal Hot Spots Demonstrated by Whole-Body 131I Scintigraphy and SPECT/CT After Transaxillary Endoscopic Thyroidectomy
Abstract: A 35-year-old woman received open thyroidectomy for a thyroid nodule that was confirmed as papillary carcinoma. Whole-body 131I scintigraphy during thyroid ablation demonstrated high uptake in the thyroid bed and multiple focal hot spots in the thorax. SPECT/CT localized the hot spots to the right chest wall and axilla, as well as to the left chest wall. The surgeon recognized these sites to concur with the transaxillary tract used during endoscopic thyroidectomy for nodular hyperplasia 8 years previously. Thus, this case illustrates how thyroidal tissue fragments seeded during endoscopic thyroidectomy can be mis...
Source: Clinical Nuclear Medicine - February 7, 2015 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

A Prospective Analysis of Thyroidectomy Outcomes in a Resource-Limited Setting
Conclusions Whilst the thyroidectomy outcomes are not equal to international standards, an acceptable standard is achievable in this resource-limited setting. Poor outcomes are multifactorial but extremes of thyroid size, extremes of operation duration and total thyroidectomies all have statistically poorer outcomes in this setting. (Source: World Journal of Surgery)
Source: World Journal of Surgery - February 7, 2015 Category: Surgery Source Type: research

Is the incidence of differentiated thyroid cancer increased in patients with tsh-secreting adenoma? report of three cases from a large consecutive series of tsh-oma.
Conclusions: The elevated incidence of DTC in patients with TSHoma suggests a possible role of TSH hypersecretion in the development of thyroid tumors. A formal high-resolution ultrasound of the thyroid is recommended in patients diagnosed with a TSHoma, especially if a long history of the pituitary tumor is suspected. Moreover, suspicion about the presence of TSHoma should be raised by the lack of suppression of TSH levels despite adequate doses of levo-thyroxine after thyroidectomy for DTC. PMID: 25647054 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - February 6, 2015 Category: Endocrinology Tags: Thyroid Source Type: research

Identification of Intermediate- to High-Risk Papillary Thyroid Carcinoma Patients Who May Be Safely Managed without the Performance of Delayed Stimulated Thyroglobulin Measurements following Total Thyroidectomy and Radioactive Iodine Therapy.
Conclusions. Based on pre- and postoperative parameters, a substantial proportion of patients with PTCs in the intermediate- and high-risk classes could avoid aggressive follow-up measures. PMID: 25649811 [PubMed] (Source: International Journal of Endocrinology)
Source: International Journal of Endocrinology - February 5, 2015 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Ipsilateral Central Neck Dissection Plus Frozen Section Examination Versus Prophylactic Bilateral Central Neck Dissection in cN0 Papillary Thyroid Carcinoma
Conclusions FSE of ipsilateral nodes is accurate in determining nodal status, allowing the extension of the central neck clearance to be reliably modulated. Routine IpsiCCD plus FSE of the ipsilateral nodes could be a valid alternative to prophylactic BilCCD since it allows accurate staging and may reduce morbidity. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - February 5, 2015 Category: Cancer & Oncology Source Type: research

[Streptococcal mediastinitis after thyroidectomy : A literature review.]
CONCLUSION: High fever and surgical site erythema in the early postoperative period after thyroid surgery can be signs of a GAS infection, which might lead to necrotizing, descending, life-threatening mediastinitis. Early diagnosis with support of computed tomography (CT) scans, immediate therapy including wound opening, lavage, intravenous antibiotic treatment with penicillin and clindamycin are vital. If treatment resistance occurs, cervical negative pressure treatment should be considered. PMID: 25648436 [PubMed - as supplied by publisher] (Source: Der Chirurg)
Source: Der Chirurg - February 5, 2015 Category: Surgery Authors: Bures C, Zielinski V, Klatte T, Swietek N, Kober F, Tatzgern E, Bobak-Wieser R, Gschwandtner E, Gilhofer M, Wechsler-Fördös A, Hermann M Tags: Chirurg Source Type: research

Thyroid Cancer in Black Thyroid Glands: The Effect of Age and Race
Conclusion: The incidence of malignancy is higher in black thyroid compared to non-black thyroid glands, specifically in Caucasians.ORL 2015;77:33-38 (Source: ORL)
Source: ORL - February 4, 2015 Category: ENT & OMF Source Type: research

[Adulthood langerhans cell histiocytosis: experience of two portuguese hospitals].
CONCLUSION: The diagnosis of adulthood Langerhans cell histiocytosis is difficult considering the diversity of clinical behavior. Frequently this also leads to diagnosis delay. Prospective international clinical trials enrolling adult patients are important. PMID: 25641287 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - February 3, 2015 Category: Journals (General) Tags: Acta Med Port Source Type: research

Bilateral recurrent laryngeal nerve injury in a specialized thyroid surgery unit: would routine intraoperative neuromonitoring alter outcomes?
ConclusionBilateral RLN palsy is a rare entity occurring in one out of 1000 cases in a specialized thyroid unit. IONM may facilitate the decision to pursue delayed surgery where the signal is lost on the first surgical side and has the potential to avoid bilateral RLN palsy following total thyroidectomy. (Source: ANZ Journal of Surgery)
Source: ANZ Journal of Surgery - February 3, 2015 Category: Surgery Authors: Leba M. Sarkis, Nisar Zaidi, Olov Norlén, Leigh W. Delbridge, Mark S. Sywak, Stan B. Sidhu Tags: Original Article Source Type: research

Adjuvant radioactive iodine therapy is associated with improved survival for patients with intermediate risk papillary thyroid cancer.
Conclusion: This is the first nationally representative study of intermediate risk PTC patients and RAI therapy demonstrating an association of RAI with improved overall survival. We recommend that this patient group should be considered for RAI therapy. PMID: 25642591 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - February 2, 2015 Category: Endocrinology Authors: Ruel E, Thomas S, Dinan M, Perkins JM, Roman SA, Ann Sosa J Tags: J Clin Endocrinol Metab Source Type: research

Bilateral Areolar Approach Endoscopic Thyroidectomy for Low-risk Papillary Thyroid Carcinoma: A Review of 137 Cases in a Single Institute
Conclusions: BAA is feasible and safe for the treatment of low-risk PTC patients, with favorable cosmesis. Thus, it is an alternative therapeutic treatment for selected patients with low-risk PTC. However, oncologic safety of BAA thyroidectomy for PTC patients needs to be verified by a large comparative series and long-term follow-up. (Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques)
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - February 1, 2015 Category: Surgery Tags: Original Articles Source Type: research

Intraoperative Neuromonitoring of the Recurrent Laryngeal Nerve in Robotic Thyroid Surgery
This study evaluated the technical feasibility and efficacy of intraoperative neuromonitoring (IONM) of the recurrent laryngeal nerve (RLN) to aid its identification and preservation during robotic thyroidectomy (RoT). IONM of the RLN was evaluated in 30 consecutive patients undergoing RoT. All patients underwent an indirect laryngoscope examination to objectively assess vocal cord function. Their Voice Handicap Index-10 (VHI-10) was measured to subjectively assess vocal cord function preoperatively and at postoperative months 1 and 3. Of the 56 RLNs at risk in 30 patients undergoing RoT, all were visualized and identified...
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - February 1, 2015 Category: Surgery Tags: Original Articles Source Type: research

Robotic Thyroid Surgery for Papillary Thyroid Carcinoma: Lessons Learned From 100 Consecutive Surgeries
Conclusions: Robotic thyroid surgery for patients with thyroid malignancy is safe and results in fewer postoperative complications than open thyroid surgery. (Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques)
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - February 1, 2015 Category: Surgery Tags: Original Articles Source Type: research

Tetraplegia After Thyroidectomy in a Patient with Cervical Spondylosis: A Case Report and Literature Review
Abstract: Cervical spondylosis is degeneration of the cervical spine that occurs during the normal course of aging, and may progress into compression of the spinal cord, or cervical spondylotic myelopathy (CSM), which can cause neurologic dysfunction. Cervical spondylosis can be identified in the majority of people older than 50 years. Many people with cervical spondylosis or CSM are asymptomatic. However, patients with CSM are at higher risk of spinal cord injury (SCI) following minor injury. A 60-year-old woman with asymptomatic cervical spondylosis underwent an elective subtotal thyroidectomy for thyroid nodules. After ...
Source: Medicine - February 1, 2015 Category: Internal Medicine Tags: Article: Clinical Case Report Source Type: research

Oxidative stress in patients with thyroidectomy and thyroparathyroidectomy under replacement therapy
The objective of this study was to evaluate the oxidative stress using malondialdehyde, nitric oxide, and catalase levels in patients with thyroidectomy and thyroparathyroidectomy. Nineteen patients with thyroidectomy, 20 patients with thyroparathyroidectomy, and 20 controls with no history of thyroid or parathyroid disease or surgery were included in the study. Serum malondialdehyde, nitric oxide, and catalase levels were examined. Levels of nitric oxide and malondialdehyde were elevated, and catalase levels decreased in patients with thyroidectomy and thyroparathyroidectomy compared with controls (p value for all the par...
Source: Endocrine - February 1, 2015 Category: Endocrinology Source Type: research

Post‐operative Systolic Blood Pressure as a risk factor for haematoma following thyroid surgery
ConclusionThis study identifies post‐operative hypertension as significantly related to development of early post‐operative haematoma. Cause for late post‐thyroidectomy bleeding remains speculative.This article is protected by copyright. All rights reserved. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - February 1, 2015 Category: ENT & OMF Authors: R P Morton, A C Vandal Tags: Original Article Source Type: research

Anaesthesia for Massive Retrosternal Thyroidectomy in a Tertiary Referral Centre
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - January 31, 2015 Category: Anesthesiology Tags: General Anesthesia Source Type: research

Thyroid Storm: An Updated Review
Thyroid storm, an endocrine emergency first described in 1926, remains a diagnostic and therapeutic challenge. No laboratory abnormalities are specific to thyroid storm, and the available scoring system is based on the clinical criteria. The exact mechanisms underlying the development of thyroid storm from uncomplicated hyperthyroidism are not well understood. A heightened response to thyroid hormone is often incriminated along with increased or abrupt availability of free hormones. Patients exhibit exaggerated signs and symptoms of hyperthyroidism and varying degrees of organ decompensation. Treatment should be initiated ...
Source: Journal of Intensive Care Medicine - January 30, 2015 Category: Intensive Care Authors: Chiha, M., Samarasinghe, S., Kabaker, A. S. Tags: Analytic Reviews Source Type: research

Thyroidectomy in a two-year old for graves’ disease
Conclusion This case is notable as it may represent the youngest patient in the literature who has undergone thyroidectomy for graves’ disease. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - January 30, 2015 Category: Surgery Source Type: research

Frequent screening with serial neck ultrasound is more likely to identify false positive abnormalities than clinically significant disease in the surveillance of intermediate risk papillary thyroid cancer patients without suspicious findings on follow-up ultrasound evaluation.
Conclusions: In ATA-intermediate risk patients that have a non-stimulated Tg less than 1.0 ng/mL and a neck US without suspicious findings after therapy, frequent US screening during follow-up is more likely to identify false positive abnormalities than clinically significant structural disease recurrence. PMID: 25632970 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - January 29, 2015 Category: Endocrinology Authors: Peiling Yang S, Bach AM, Michael Tuttle R, Fish SA Tags: J Clin Endocrinol Metab Source Type: research

What is the Remission Rate for Antithyroid Drug Treatment for Hyperthyroidism in Children?
Discussion The thyroid gland secrets two hormones – T4 which is a prohormone and T3 which is the biologically active hormone. Receptors for T3 are found in nearly all body tissues. T3 regulates metabolism and energy production. Organs most affected are the heart, liver and central nervous system as well as growth of the fetus and child. Hyperthyroidism is common with a prevalence rate of about 1-2% for women and 0.2% for men. The most common cause of thyrotoxicosis is Grave’s disease where autoantibodies to thyroid stimulating hormone (TSH) exist. These autoantibodies attach to thyroid tissue TSH receptors and...
Source: PediatricEducation.org - January 26, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Infected tracheal diverticulum: a rare association with alpha-1 antitrypsin deficiency
We report a case of a 69-year-old woman who was hospitalized after presenting with fever, fatigue, pleuritic chest pain, and a right neck mass complicated by dysphagia. Her medical history was significant: pulmonary emphysema (alpha-1 antitrypsin deficiency); bronchiectasis; and thyroidectomy. On physical examination, she presented diminished breath sounds and muffled heart sounds, with a systolic murmur. Laboratory tests revealed elevated inflammatory markers, a CT scan showed an air-filled, multilocular mass in the right tracheal wall, and magnetic resonance imaging confirmed the CT findings. Fiberoptic bronchoscopy fail...
Source: Jornal Brasileiro de Pneumologia - January 25, 2015 Category: Respiratory Medicine Source Type: research

A six-minute step test protocol for the investigation of dyspnea
We report a case of a 69-year-old woman who was hospitalized after presenting with fever, fatigue, pleuritic chest pain, and a right neck mass complicated by dysphagia. Her medical history was significant: pulmonary emphysema (alpha-1 antitrypsin deficiency); bronchiectasis; and thyroidectomy. On physical examination, she presented diminished breath sounds and muffled heart sounds, with a systolic murmur. Laboratory tests revealed elevated inflammatory markers, a CT scan showed an air-filled, multilocular mass in the right tracheal wall, and magnetic resonance imaging confirmed the CT findings. Fiberoptic bronchoscopy fail...
Source: Jornal Brasileiro de Pneumologia - January 25, 2015 Category: Respiratory Medicine Source Type: research