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Doppler ultrasonography before thyroidectomy is not useful to prevent cerebrovascular accident.
Authors: Raffaelli M, Santoliquido A, Tondi P, Revelli L, Kateta Tshibamba P, DE Crea C, D'Amore A, Bellantone R, Lombardi CP Abstract Surgical manipulation of the cervical vascular bundle during neck surgery may promote a thromboembolic event. We evaluated if thyroid surgery is associated with any alterations in the carotid artery wall that would imply an augmented risk of cerebrovascular accident (CVA). A prospective evaluation of a consecutive series of patients who underwent total thyroidectomy was performed. High resolution Doppler ultrasonography (HR-DU) was performed the day before and three days after surge...
Source: Acta Otorhinolaryngologica Italica - May 29, 2015 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Effect of Thyroid Function on MNU-Induced Mammary Carcinogenesis.
Abstract Mammary cancer is a disease that affects many women. Extensive research has been conducted to elucidate which variables are involved in the development of this cancer. Studies have highlighted thyroid function as a modulator of tumor growth and development. Thyroxine and 3,3',5-triiodothyronine are responsible for regulating the development, differentiation, homeostasis, and metabolism of cells in the body including mammary tissue. Thyroid hormones also have estrogen-like effects on mammary cancer cell growth by regulating the estrogen receptor. The present study was designed to determine whether medically...
Source: Zoological Science - May 27, 2015 Category: Zoology Authors: Vermey ML, Marks GT, Baldridge MG Tags: Zoolog Sci Source Type: research

MiR-9 and miR-21 as prognostic biomarkers for recurrence in papillary thyroid cancer
In conclusion, our results support the potential clinical value of miR-9 and miR-21 as prognostic biomarkers for recurrence in papillary thyroid carcinoma. (Source: Clinical and Experimental Metastasis)
Source: Clinical and Experimental Metastasis - May 26, 2015 Category: Cancer & Oncology Source Type: research

Impact of postoperative magnesium levels on early hypocalcemia and permanent hypoparathyroidism after thyroidectomy
ConclusionHypomagnesemia is significantly associated with early hypocalcemia and permanent hypoparathyroidism after thyroidectomy. Magnesium levels should be closely monitored in patients with postthyroidectomy hypocalcemia. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 (Source: Head and Neck)
Source: Head and Neck - May 26, 2015 Category: ENT & OMF Authors: Aoife Garrahy, Matthew S. Murphy, Patrick Sheahan Tags: Original Article Source Type: research

Thyroid thyrothymic extension: An anatomic study in a surgical series
ConclusionThe TTE is a commonly encountered projection from the inferior thyroid pole. Awareness of the TTE is important to ensure complete total thyroidectomy. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 (Source: Head and Neck)
Source: Head and Neck - May 26, 2015 Category: ENT & OMF Authors: Patrick Sheahan, Fergal O'Duffy Tags: Original Article Source Type: research

Thyroid cancer in patients with toxic nodular goiter—is the incidence increasing?
Conclusions No significant increase in the rate of carcinoma was observed in patients with TNG. As a result, the risk benefit analysis should not change when considering therapeutic options for TNG. (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - May 23, 2015 Category: Surgery Source Type: research

Papillary thyroid carcinoma: does the association with Hashimoto's thyroiditis affect the clinicopathological characteristics of the disease?
Conclusions A high proportion of papillary thyroid carcinoma cases are associated with Hashimoto's thyroiditis. There are associations among these cases with several histopathological factors already recognized for their prognostic value, which by themselves could impact outcomes. (Source: Brazilian Journal of Otorhinolaryngology)
Source: Brazilian Journal of Otorhinolaryngology - May 23, 2015 Category: ENT & OMF Source Type: research

Epiphora After Radioactive Iodine Therapy in a Low-Risk Patient
Abstract: It has been demonstrated that radioactive iodine therapy (RIT) is very useful for ablating remnant thyroid tissue or metastatic lesions after total thyroidectomy in well-differentiated thyroid cancer. Epiphora as a result of lacrimal drainage system obstruction is a rare complication of RIT. Previous studies have shown that most patients with epiphora after RIT are old ages, females, and with high cumulative radioactive iodine dose. Here, we report on a case of epiphora with low-risk factors including young ages, male, and 5.5-GBq (150-mCi) dose in the first RIT. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - May 20, 2015 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Predictive factors for difficult robotic thyroidectomy using bilateral axillo‐breast approach
This article is protected by copyright. All rights reserved. (Source: Head and Neck)
Source: Head and Neck - May 20, 2015 Category: ENT & OMF Authors: Hee Yong Kwak, Hoon Yub Kim, Hye Yoon Lee, Seung Pil Jung, Sang Uk Woo, Gil Soo Son, Jae Bok Lee, Jeoung Won Bae Tags: Original Article Source Type: research

Prediction of treatment response to 131 I therapy by diffuse hepatic uptake intensity on post-therapy whole-body scan in patients with distant metastases of differentiated thyroid cancer
Conclusions In patients with iodine-avid distant metastases, intensity of DHU on 131I post-therapy scan correlated with subsequent percentage serum sTg reduction. Also, intense DHU could be one of the predictors of remission in these patients. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - May 17, 2015 Category: Nuclear Medicine Source Type: research

Robot-assisted transaxillary thyroidectomy: Surgical technique
Publication date: Available online 13 May 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): Laurent Abramovici , César Cartier , Guillemette Pierre , Renaud Garrel Robot-assisted transaxillary thyroid surgery avoids the need for a neck incision. It consists of thyroid lobectomy and isthmectomy for moderately large unilateral benign nodules. The surgical imperatives are the same as for conventional surgery, but with differences in terms of patient positioning, surgical incision, equipment, surgical technique and indications. The purpose of this article is to describe the equipment, pat...
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - May 14, 2015 Category: ENT & OMF Source Type: research

[Transaxillary robot-assisted thyroidectomy : First experiences with a new operation technique].
CONCLUSION: The TRAT procedure still has low acceptance by German patients but patient satisfaction after surgery is high due to the cosmetic result. The extended operation time, new complications (e.g. transient plexus palsy) and a potentially increased rate of transient recurrent laryngeal nerve palsy must be critically considered. PMID: 25971612 [PubMed - as supplied by publisher] (Source: Der Chirurg)
Source: Der Chirurg - May 14, 2015 Category: Surgery Authors: Eckhardt S, Maurer E, Fendrich V, Bartsch DK Tags: Chirurg Source Type: research

Bilobar thyroid agenesis with primary hyperparathyroidism: report of a case
In this report, we present a case of bilateral lobe agenesis with hypertrophied isthmus and high calcium and elevated PTH levels which were detected during routine examinations of a 49-year-old female patient. Some findings consistent with parathyroid pathology on the right side were determined in parathyroid scintigraphy. At thyroid scan and neck ultrasonography there was no sign of bilateral thyroid tissue except a mass localized isthmus. The right lower parathyroidectomy and thyroidectomy for isthmus were performed; the pathology report was shown as parathyroid adenoma and nodular colloidal goiter. This case of bilobar ...
Source: Surgery Today - May 13, 2015 Category: Surgery Source Type: research

A Rare Silent Killer: Right Atrial Metastasis of Thyroid Hürthle Cell Carcinoma
We describe the case of a 57-year-old female with thyroid HCC, 5 years after total thyroidectomy, who presented with dyspnea associated with hypoxia and hypotension. The computed tomography angiogram showed extensive pulmonary embolism and a 6-cm right atrial mass while the lower-extremity deep vein thrombosis studies were negative. This patient received a cardiac thrombectomy using cardiopulmonary bypass support. However, intraoperatively, we found out that the mass was from the mediastinum, directly extending into the heart and clearly unresectable since it effaced at least 1/3 of the right atrial wall. The core biopsy o...
Source: Case Reports in Oncology - May 12, 2015 Category: Cancer & Oncology Source Type: research

Pathophysiology of airway obstruction caused by wound hematoma after thyroidectomy: an ex vivo study
Conclusions This study suggests that even pressures of 250 mmHg in neck-hematomas would be insufficient to cause a mechanical airway occlusion. (Source: European Surgery)
Source: European Surgery - May 12, 2015 Category: Surgery Source Type: research

Thyroid Cancer Presentation and Treatment in the United States
Conclusions This study provides insight into the patterns of papillary thyroid cancer care in the general population. The findings from this study indicate adherence to guideline recommendations in that family history of thyroid disease/cancer, in addition to tumor characteristics, does appear to inform treatment practices, especially among low-risk patients. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - May 10, 2015 Category: Cancer & Oncology Source Type: research

Use of the Nerve Integrity Monitor during Thyroid Surgery Aids Identification of the External Branch of the Superior Laryngeal Nerve
Conclusion Using the NIM and meticulous dissection of the upper thyroid pole improves EBSLN identification. As the EBSLN is at risk during thyroidectomy and can lead to voice morbidity, the NIM can aid identification of the EBSLN and provide a functional assessment of the EBSLN after thyroid resection. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - May 10, 2015 Category: Cancer & Oncology Source Type: research

Erratum to: Surgical completeness of robotic thyroidectomy: a prospective comparison with conventional open thyroidectomy in papillary thyroid carcinoma patients
(Source: Surgical Endoscopy)
Source: Surgical Endoscopy - May 7, 2015 Category: Surgery Source Type: research

Transaxillary Thyroidectomies: A Comparative Learning Experience of Robotic vs Endoscopic Thyroidectomies
Conclusion In terms of outcome, both techniques are comparable at least in the initial phase. Based on our early experience, the endoscopic technique may be less intuitive with a longer learning curve, although at steady state, it may be the quicker procedure. This is relevant for low- to moderate-volume centers starting their transaxillary thyroidectomy program. (Source: Otolaryngology - Head and Neck Surgery)
Source: Otolaryngology - Head and Neck Surgery - May 7, 2015 Category: ENT & OMF Authors: Kiong, K. L., Iyer, N. G., Skanthakumar, T., Ng, J. C. F., Tan, N. C., Tay, H. N., Tan, H. K. Tags: Endocrine Surgery Source Type: research

I-131 remnant ablation after thyroidectomy induced hepatotoxicity in a case of thyroid cancer
Conclusion: To the best of our knowledge, this is the rare description of DILI complications in thyroidectomy patient due to I-131 ablation therapy. The patient responds to glucocorticoid therapy well, but not basic hepatic protection treatment. Even though this is only a single case, it reminds physicians make DILI in early consideration when patient present liver injury after I-131 ablation therapy. (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - May 7, 2015 Category: Gastroenterology Authors: Rong LinOmar BanafeaJin Ye Source Type: research

C-Cell Neoplasia in Asymptomatic Carriers of Mutation in Extracellular Cysteine-Rich and Intracellular Tyrosine Kinase Domain
Germline mutations in RET proto-oncogene associated with multiple endocrine neoplasia type 2 (MEN2) may affect codons for the extracellular cysteine-rich (ECR) or the intracellular tyrosine kinase (ITK) domain of the transmembrane receptor tyrosine kinase protein. We compared C-cell pathology in asymptomatic carriers of RET mutation affecting the two domains. Twenty-two asymptomatic carriers (median age 9.5 years), 10 with mutations in the ECR (codons 634, 611, 618 and 620) and 12 with mutations in the ITK domain (codons 804, 790, 891 and 918) underwent total thyroidectomy. (Source: Human Pathology)
Source: Human Pathology - May 6, 2015 Category: Pathology Authors: Rita Abi-Raad, Renu K. Virk, Catherine Dinauer, A. Prasad, Raffaella A. Morotti, Christopher K. Breuer, Julie A. Sosa, Robert Udelsman, Scott A. Rivkees, Manju L. Prasad Tags: Original Contribution Source Type: research

Therapeutic Effectiveness of Screening for Multiple Endocrine Neoplasia Type 2A.
CONCLUSIONS: Screening efforts need to focus on sporadic-appearing MTC to deplete the pool of unrecognized carriers of ATA level B and A mutations and enable earlier pre-emptive thyroidectomy in their offspring. PMID: 25946031 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - May 6, 2015 Category: Endocrinology Authors: Machens A, Dralle H Tags: J Clin Endocrinol Metab Source Type: research

Our Experience with Femoro-Femoral Bypass in the Management of Critical Airway Problems
Abstract The authors present a case report of a 64 year old male patient with thyroid mass and extensive secondaries of the neck and infiltration of the trachea producing severe tracheal stenosis at the level of the thoracic inlet presenting with stridor. Due to the large mass, endotracheal intubation was ruled out; hence a femoro-femoral Cardiopulmonary Bypass was done followed by a median sternotomy, resection of the involved tracheal segment, a total thyroidectomy with neck dissection and finally a tracheal end-to-end anastomosis. The surgery was done in May 2011. (Source: Indian Journal of Otolaryngology and ...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - May 5, 2015 Category: ENT & OMF Source Type: research

Amiodarone and the thyroid.
Abstract Amiodarone, a benzofuranic iodine-rich antiarrhythmic drug, causes thyroid dysfunction in 15-20% of cases. Amiodarone can cause both hypothyroidism (AIH, amiodarone-induced hypothyroidism) and thyrotoxicosis (AIT, amiodarone-induced thyrotoxicosis). AIH is treated by L-thyroxin replacement and does not need amiodarone discontinuation. There are two main forms of AIT: type 1, a form of true iodineinduced hyperthyroidism; and type 2, a drug-induced destructive thyroiditis. However, mixed/indefinite forms exist, contributed to by both pathogenic mechanisms. Type 1 AIT usually occurs in diseased thyroid glands...
Source: Endokrynologia Polska - May 4, 2015 Category: Endocrinology Authors: Jabrocka-Hybel A, Bednarczuk T, Bartalena L, Pach D, Ruchała M, Kamiński G, Kostecka-Matyja M, Hubalewska-Dydejczyk A Tags: Endokrynol Pol Source Type: research

Association between Decreased Serum Parathyroid Hormone after Total Thyroidectomy and Persistent Hypoparathyroidism.
Conclusions PTH declined on the first day after thyroidectomy. PTH levels <7 ng/L on the first day after surgery might be associated with persistent hypoparathyroidism. CND, thyroiditis, and iatrogenic parathyroidectomy increased the risk of hypoparathyroidism. PMID: 25923249 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - May 2, 2015 Category: Research Tags: Med Sci Monit Source Type: research

Clusterin transcript variants expression in thyroid tumor: a potential marker of malignancy?
Conclusions: Our results suggest the existence of a specific alteration of CLU2:CLU1 ratio towards CLU2, thus providing the first circumstantial evidence for the potential use of CLU transcript variants as effective biomarkers for a more accurate assessment of the so called “indeterminate” thyroid nodules. (Source: BMC Cancer)
Source: BMC Cancer - May 2, 2015 Category: Cancer & Oncology Authors: Paolo FuzioAnna NapoliAnna CiampolilloSerafina LattaruloAngela PezzollaNicoletta NuzzielloSabino LiuniFrancesco GiorginoEugenio MaioranoElda Perlino Source Type: research

Characterization of Papillary Thyroid Microcarcinomas Using Sonographic Features in Malignant Papillary Thyroid Cancer: A Retrospective Analysis
This study aimed to determine the ultrasonographic characteristics of papillary thyroid carcinoma. The ultrasonographic and pathological data of 2453 thyroid nodules in a cohort of 1895 Chinese patients who underwent thyroidectomy from January 2010 to December 2012 were retrospectively reviewed. Anteroposterior and transversal (AP/TR) diameters ≥1, solid structure, infiltrative margins, hypoechoic appearance, and microcalcifications were more common in malignant nodules than in benign nodules (P  (Source: Medicine)
Source: Medicine - May 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Frequency and severity of globus pharyngeus symptoms in patients undergoing thyroidectomy: a pre-post short term cross-sectional study
Background: Globus pharyngeus is a sensation of a lump or foreign body in the throat, sometimes associated with thyroid diseases and surgery. Previous studies investigated this condition with contradictory results, mainly because not standardized instruments of measure were used. The aim of this study was to evaluate the prevalence and severity of globus pattern symptoms in a population of patients three months after a thyroidectomy, and the reduction or increase of pre-existing symptoms or the onset of new symptoms. Methods: Ninety-five patients (65 women, 30 men, mean age 56.03 ± 12.45) were assessed for globus patt...
Source: BMC Surgery - May 1, 2015 Category: Surgery Authors: Fabrizio ConsortiRosaria MancusoValentina MingarelliEugenio PretoreAlfredo Antonaci Source Type: research

Variations in Single/Two Stage Thyroidectomies for Cancer May be Due to Differences in Thyroid Fine Needle Cytology Provision
Conclusion Variation in thyroid cytology provision may increase TST rates. Thyroid cytology should be concentrated in high volume centres with specialist thyroid cytopathologists. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - May 1, 2015 Category: Surgery Source Type: research

Trans-oral Robotic Surgery and Surgeon-Performed Trans-oral Ultrasound For Intraoperative Location and Excision of an Isolated Retropharyngeal Lymph Node Metastasis of Papillary Thyroid Carcinoma
Conclusions Retropharyngeal metastases are a known location for regional spread of WDTC and are amenable to evaluation and biopsy using TO-US by both surgical and non-surgical providers. In cases where lateral neck dissection has already been performed or when traditional transcervical or transmandibular approaches to the retropharynx represent a comparatively extensive procedure for isolated metastases, SP-TO-US and TORS are safe and effective combination for surgical management of disease. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - May 1, 2015 Category: Endocrinology Source Type: research

Economic Benefits of Ultrasonic devices in thyroidectomy
The use of ultrasonic devices (UD) in thyroidectomy may have significant economic impact due to improved efficiency and benefits of clinical outcomes without increasing rates of surgical complications. To fully characterize the potential economic benefit of UD in thyroidectomy, the objective of this study was to develop a provider budget impact model to quantify potential cost savings over conventional surgical techniques. (Source: Value in Health)
Source: Value in Health - May 1, 2015 Category: Global & Universal Authors: C. Hsiao, H. Cheng, C. Tao, A.S. Chawla, E.C. Faulkner, S. DeRamus Source Type: research

Mucoepidermoid carcinoma in a thyroglossal duct remnant
Conclusion This case adds weight to the literature favouring surgical excision of thyroglossal duct remnants due to the risk of malignant transformation. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - April 30, 2015 Category: Surgery Source Type: research

Abstract P3-04-11: Thyroid hormone up-regulates estrogenic and pro-carcinogenic signaling, inducing a basaloid and more motile phenotype in only steroid receptor positive breast cancer cells
Conclusions: We have demonstrated in Stage I breast cancer patients with minimal systemic treatment, that the administration of TH was associated with a significantly shortened disease free and disease specific survival, only in patients whose tumors expressed SR. TH administered to SR+ cell lines, particularly when co-administered with E2 at therapeutic/physiologic doses, upregulates and activates ER, cell proliferation, a more aggressive and motile basaloid phenotype. Citation Format: Ann D Thor, Zeying Fan, Reema Wahdan-Alaswad, Susan M Edgerton. Thyroid hormone up-regulates estrogenic and pro-carcinogenic signaling, in...
Source: Cancer Research - April 30, 2015 Category: Cancer & Oncology Authors: Thor, A. D., Fan, Z., Wahdan-Alaswad, R., Edgerton, S. M. Tags: Poster Session Abstracts Source Type: research

Serum calprotectin: a new potential biomarker for thyroid papillary carcinoma
In conclusion, serum calprotectin levels is increased in patients with PTC, and calprotectin is positively correlated with TOS and LOOH. Serum calprotectin levels is significantly decreased after total thyroidectomy. (Source: Tumor Biology)
Source: Tumor Biology - April 29, 2015 Category: Cancer & Oncology Source Type: research

Validation of intra-operative parathyroid hormone and its decline as early predictors of hypoparathyroidism after total thyroidectomy: A prospective cohort study
Total thyroidectomy is a preferred surgical technique for benign as well as malignant thyroid pathologies, but many a times can cause hypoparathyroidism. The aim of this study is to evaluate the intra-operative parathyroid hormone (ioPTH) level and its decline as predictors for post-operative hypoparathyroidism after total thyroidectomy. (Source: International Journal of Surgery)
Source: International Journal of Surgery - April 29, 2015 Category: Surgery Authors: Shailesh Gupta, Poras Chaudhary, Chikkala K. Durga, Dipankar Naskar Tags: Original research Source Type: research

A comparison of Quality of life between open and endoscopic thyroidectomy for papillary thyroid cancer
Conclusion Current findings suggest that ET may offer more rapid recovery of emotional and physical function than OT. This article is protected by copyright. All rights reserved. (Source: Head and Neck)
Source: Head and Neck - April 27, 2015 Category: ENT & OMF Authors: MyungChul Lee, Hoon Park, Byeong‐Cheol Lee, Guk‐Haeng Lee, IkJoon Choi Tags: Original Article Source Type: research

Recovery from Permanent Hypoparathyroidism after Total Thyroidectomy.
CONCLUSIONS: Although recovery from permanent hypoparathyroidism is rare, patients should be monitored for serum PTH levels so that unnecessary treatments such as calcium and vitamin D supplementation can be avoided. PMID: 25905773 [PubMed - as supplied by publisher] (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - April 24, 2015 Category: Endocrinology Tags: Thyroid Source Type: research

Clinical relevance and surgical anatomy of non-recurrent laryngeal nerve: 7 year experience
Conclusions Thyroid surgeons should understand the variable topography of inferior laryngeal nerves. Non-recurrent laryngeal nerve is a vulnerable asymptomatic anatomical variation of recurrent laryngeal nerve. Optimal NRLN identification should be done prior to operation by routine X-ray and ultrasonography, based on abnormality of cervical vessels. (Source: Surgical and Radiologic Anatomy)
Source: Surgical and Radiologic Anatomy - April 24, 2015 Category: Anatomy Source Type: research

Initial learning curve of single-incision transaxillary robotic hemi- and total thyroidectomy – a single team experience from Europe
The primary advantage of robotic thyroidectomy is to avoid a neck scar. On the other hand, this sophisticated technique implies some potential risks otherwise not associated with conventional thyroidectomy, increased costs, and prolonged operating times. With all these factors being an important issue, we analysed the data of our initial European series in order to understand the nature of the learning curve for this technique. (Source: International Journal of Surgery)
Source: International Journal of Surgery - April 24, 2015 Category: Surgery Authors: Balazs B. Lörincz, Chia-Jung Busch, Nikolaus Möckelmann, Rainald Knecht Tags: Original research Source Type: research

Late tracheal perforation after total thyroidectomy. Conservative management.
PMID: 25912161 [PubMed - as supplied by publisher] (Source: Cirugia eEspanola)
Source: Cirugia eEspanola - April 23, 2015 Category: Surgery Authors: González-Sánchez-Migallón E, Guillén-Paredes P, Flores-Pastor B, Miguel-Perelló J, Aguayo-Albasini JL Tags: Cir Esp Source Type: research

Intraoperative Nerve Monitoring and Vocal Cord Paralysis: Controlling Bias
We thank Drs Nguyen and Wang for their thoughtful comments on our article and for the opportunity to discuss this topic. The primary question raised is how use rates measured with the Nationwide Inpatient Sample (NIS) in our study are different from the 2 surveys referenced in our article, which cite higher use rates. The authors cite the American Academy of Otolaryngology−Head and Neck Surgery’s CPT coding guidelines for billing of intraoperative nerve monitoring (IONM) during thyroidectomy, which state that IONM billing codes should be used only if a dedicated monitoring professional is performing the monitoring. (So...
Source: Journal of the American College of Surgeons - April 22, 2015 Category: Surgery Authors: Thomas K. Chung, Eben L. Rosenthal, John R. Porterfield, William R. Carroll, Joshua Richman, Mary T. Hawn Tags: Letter Source Type: research

Intraoperative Nerve Monitoring and Vocal Cord Paralysis: Have Rates Really Risen after the Adoption of Intraoperative Nerve Monitoring?
We read with great interest the article, “Examining National Outcomes after Thyroidectomy with Nerve Monitoring” by Chung and colleagues.1 The authors used the Nationwide Inpatient Sample, a national database funded by the US Agency for Healthcare Research and Quality that collects data from a 20% stratified sample of hospitals around the country. Data collected include diagnoses and charge data. Cases from the outpatient or ambulatory setting are excluded. The authors retrospectively analyzed 243,527 thyroidectomies during the time period from 2008 to 2011 using the Nationwide Inpatient Sample. (Source: Journal of the...
Source: Journal of the American College of Surgeons - April 22, 2015 Category: Surgery Authors: Chau Nguyen, Marilene Wang Tags: Letter Source Type: research

Overlapping Morphologic and Immunohistochemical Features of Hashimoto Thyroiditis and IgG4-Related Thyroid Disease
Abstract Immunoglobulin G4-related disease (IgG4-RD) is an emerging clinicopathologic entity characterized by both IgG4+ plasma cell infiltration and fibrosis in one or more organs, prototypically pancreas or salivary/lacrimal glands. IgG4-RD in the thyroid (IgG4-RTD) is an area of active study, and the relationship between IgG4-RTD and Hashimoto thyroiditis is not fully delineated due to their overlapping histologic features. Retrospective review was performed of all thyroidectomy cases demonstrating lymphocytic inflammation at a single institution over a 4-year period. Approximately half (23/38) of patients had ...
Source: Endocrine Pathology - April 22, 2015 Category: Pathology Source Type: research

Total Thyroidectomy versus Lobectomy as Initial Operation for Small Unilateral Papillary Thyroid Carcinoma: A Meta-Analysis
Consensus guidelines have recommended total thyroidectomy for papillary thyroid carcinoma (PTC) > 1 cm. However, the optimal surgical approach for small and unilateral ( (Source: Surgical Oncology)
Source: Surgical Oncology - April 22, 2015 Category: Surgery Authors: Francisco Igor B. Macedo, Vijay K. Mittal Source Type: research

Should central lymph node dissection be considered for all papillary thyroid microcarcinoma?
CONCLUSION: CLNM in PTMC is highly prevalent in male sex, tumor size ≥ 0.5 cm, extrathyroidal extension, and multifocality. Even in PTMC patients without these risk factors, the incidence of CLNM is rather higher than expected, and the complication rate of thyroidectomy with CLND is acceptable. Thus, CLND should be considered in all patients with PTMC. PMID: 25913730 [PubMed - as supplied by publisher] (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 22, 2015 Category: Surgery Authors: Chang YW, Kim HS, Kim HY, Lee JB, Bae JW, Son GS Tags: Asian J Surg Source Type: research

Hypoparathyroidism after Total Thyroidectomy: Incidence and Resolution
Parathyroid hormone (PTH) levels are often measured after thyroid surgery and are used to detect patients at risk for postoperative hypoparathyroidism. However, there is a lack of consensus in the literature about how to define the recovery of parathyroid gland function and when to classify hypoparathyroidism as permanent. The goals of this study were to determine the incidence of low postoperative PTH in total thyroidectomy patients and to monitor their time course to recovery of parathyroid gland function. (Source: Journal of Surgical Research)
Source: Journal of Surgical Research - April 21, 2015 Category: Surgery Authors: Kathryn Ritter, Dawn Elfenbein, David Schneider, Herbert Chen, Rebecca S. Sippel Source Type: research

Should surgical outcomes be published?
Despite publishing surgical outcomes being a positive step forwards in the progression of England’s healthcare system, it has no doubt been faced with criticism and reservations. This review article aims to discuss the pros and cons of publishing individual surgical outcomes, as well as the challenges faced. Publishing outcomes requires data from a number of sources such as national clinical audits, hospital episode statistics, patient-reported outcomes, registers and information from revalidation. As yet, eight surgical specialties have begun publishing their data, including cardiac (coronary artery bypass graft, va...
Source: JRSM - April 21, 2015 Category: UK Health Authors: Chou, E., Abboudi, H., Shamim Khan, M., Dasgupta, P., Ahmed, K. Tags: Review Source Type: research

Predictive factors of contralateral paratracheal lymph node metastasis in unilateral papillary thyroid carcinoma
Conclusion Primary tumor size &gt;1 cm, capsular/extracapsular invasion, pretracheal/prelaryngeal LN metastasis and lateral neck LN metastasis are predictive factors of contralateral paratracheal LN metastasis in unilateral PTC, which may help to determine the optimal extent of CND in patients with PTC. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - April 18, 2015 Category: Surgery Source Type: research

Surgical treatment for dominant malignant nodules of the isthmus of the thyroid gland: A case control study
Appropriate surgical treatment of papillary thyroid carcinomas (PTC) located in the isthmus remains controversial. The aim of this study was to evaluate the clinicopathological characteristics of PTC of the isthmus compared to tumors located in the thyroid lobes, to identify differences between PTC and microcarcinomas of the isthmus, and to use these findings to establish total thyroidectomy as an appropriate surgical resection for treating these tumors. (Source: International Journal of Surgery)
Source: International Journal of Surgery - April 18, 2015 Category: Surgery Authors: Theodore Karatzas, Georgios Charitoudis, Dimitrios Vasileiadis, Stylianos Kapetanakis, Ioannis Vasileiadis Tags: Original Research Source Type: research

Substernal Goiter: When is a Sternotomy Required?
Sternotomy for substernal goiters (SSG) is associated with greater morbidity than a cervical approach to thyroidectomy. We sought to identify predictors for sternotomy as a surgical approach for the removal of SSG, and analyzed the preoperative and postoperative characteristics of patients with SSG compared to those with large goiters contained entirely within the neck, or a cervical goiter (CG). (Source: Journal of Surgical Research)
Source: Journal of Surgical Research - April 18, 2015 Category: Surgery Authors: Luke Nankee, Herbert Chen, David F. Schneider, Rebecca S. Sippel, Dawn M. Elfenbein Source Type: research