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Closure of tracheoesophageal fistula with prefabricated deltopectoral flap.
Abstract Tracheoesophageal fistula (TEF) is a serious complication associated with impaired quality of life. However, a successful TEF closure is difficult owing to the high incidence of recurrence. We utilized a prefabricated deltopectoral (DP) flap for closure of a TEF that occurred after an extended total thyroidectomy. Prefabrication of the inner soft tissue lining the DP flap with a split skin graft was performed prior to surgical closure of a TEF. Esophageal and tracheal mucosa were sutured to the split thickness side and full thickness side of the prefabricated DP flap, respectively. A successful closure of ...
Source: Asian Journal of Surgery - March 24, 2014 Category: Surgery Authors: Murono S, Ishikawa E, Nakanishi Y, Endo K, Kondo S, Wakisaka N, Yoshizaki T Tags: Asian J Surg Source Type: research

Postoperative recurrent tracheoesophageal fistula: An unusual complication of oxidized regenerated cellulose (Surgicel®)
We present a case of recurrent tracheoesophageal fistula (RTEF) repaired by Surgicel®. In this case, tracheoesophageal fistula (TEF) recurred due to migration of Surgicel into the tracheal and esophageal lumen. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - March 14, 2014 Category: ENT & OMF Authors: Zafer Dokumcu, Kamer Polatdemir, Coskun Ozcan, Ata Erdener Tags: Case reports Source Type: research

Recurrent tracheoesophageal fistula in children with repaired esophageal atresia and the usefulness of flexible bronchoscopy.
PMID: 24630317 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - March 13, 2014 Category: Respiratory Medicine Authors: Platnaris A, Lianou D, Kaditis AG Tags: Arch Bronconeumol Source Type: research

BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis.
Abstract Esophageal atresia with tracheoesophageal fistula (EA/TEF) is a serious human birth defect, in which the esophagus ends before reaching the stomach, and is aberrantly connected with the trachea. Several mouse models of EA/TEF have recently demonstrated that proper dorsal/ventral (D/V) patterning of the primitive anterior foregut endoderm is essential for correct compartmentalization of the trachea and esophagus. Here we elucidate the pathogenic mechanisms underlying the EA/TEF that occurs in mice lacking the BMP antagonist Noggin, which display correct dorsal/ventral patterning. To clarify the mechanism of...
Source: Developmental Biology - March 12, 2014 Category: Biology Authors: Fausett SR, Brunet LJ, Klingensmith J Tags: Dev Biol Source Type: research

Tracheoplasty using the thymus against tracheo‐esophageal fistula due to necrotizing tracheobronchitis in a very low birth weight infant
We report a case of a very low birth weight infant treated successfully with tracheoplasty using the thymus against tracheo‐esophageal fistula due to necrotizing tracheobronchitis. A baby boy was born at 31 weeks gestation with a birth body weight of 1,230 g. Suddenly on Day 19, his respiration deteriorated, and a flexible bronchofiberscopy showed tracheostenosis, tracheomalacia, and tracheal diverticula. On Day 21, his abdomen became significantly distended, and a flexible bronchofiberscopy showed a tracheo‐esophageal fistula due to a rupture of the diverticula. On Day 105, during surgery, we confirmed necrosis of t...
Source: Pediatric Pulmonology - March 9, 2014 Category: Respiratory Medicine Authors: Hisaya Hasegawa, Yuzo Nagase, Miho Sakai, Nobuhide Henmi, Shio Tsuruta Tags: Case Report Source Type: research

Anaesthesia for specialist surgery in infancy
Abstract: Common indications for neonatal surgery include inguinal hernias and hypertrophic pyloric stenosis. Less common conditions that have major implications for anaesthesia include tracheoesophageal fistula, congenital diaphragmatic hernia, exomphalos, gastroschisis and congenital lobar emphysema. The anaesthetic management of these conditions is outlined in this article. (Source: Anaesthesia and intensive care medicine)
Source: Anaesthesia and intensive care medicine - March 1, 2014 Category: Anesthesiology Authors: Gillian Lauder, Helen Hume-Smith Tags: Neonatal anaesthesia Source Type: research

Endoscopic clip for closure of persistent tracheoesophageal fistula in an infant
(Source: The Laryngoscope)
Source: The Laryngoscope - February 22, 2014 Category: ENT & OMF Authors: Evan J. Propst, Simon C. Ling, Alan Daneman, Jacob C. Langer Tags: How I Do It Source Type: research

[H-type tracheoesophageal fistula in neonates: Different therapeutic approaches.]
PMID: 24560732 [PubMed - as supplied by publisher] (Source: Anales de Pediatria)
Source: Anales de Pediatria - February 20, 2014 Category: Pediatrics Authors: González Temprano N, Viguria Sánchez N, Ayuso González L, Pérez Martínez A Tags: An Pediatr (Barc) Source Type: research

Efficacy of bronchial fiberscope in esophageal fistula caused by necrotizing bronchitis
This report describes a case in which the use of a bronchial fiberscope in making an early diagnosis facilitated appropriate management and survival. The proactive use of a bronchial fiberscope in regard to this disease, which has a high fatality rate, may save lives. (Source: Pediatrics International)
Source: Pediatrics International - February 18, 2014 Category: Pediatrics Authors: Jun Matsui, Sayuri Nakahara, Nanae Kikuoka, Hidemi Tsutsui, Ouki Furukawa, Shoji Kitamura, Takahide Yanagi, Shigeki Koshida, Hisaya Hasegawa Tags: PATIENT REPORT Source Type: research

The role of esophageal stent placement in the management of postesophagectomy anastomotic leak
Conclusion: Endoluminal stent implantation is an effective and safe option in the management of postesophagectomy leaks. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 4, 2014 Category: Gastroenterology Authors: Mohammad A Al-issaTorben I PetersenAbdulsalam Y TahaJaffar S Shehatha Source Type: research

Laryngotracheobronchoscopy prior to esophageal atresia and tracheoesophageal fistula repair—its use and importance
Conclusions: LTB performed just prior to the definitive surgical procedure in EA and EA-TEF would diagnose, document and may aid in the surgical management strategies. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - February 1, 2014 Category: Surgery Authors: Nitin Sharma, M. Srinivas Tags: Independent Original Articles Source Type: research

Esophageal atresia: a critical review of management at a single center in Algeria
Summary The purpose was to study the outcomes and factors affecting the survival of esophageal atresia in our center. A retrospective analysis of 86 cases of esophageal atresia (EA) over a 10‐year period was performed with 46 boys and 42 girls. Demographic data, birth weight, gestational age, consanguinity, incidence of associated anomalies, place of delivery, history of feeding, and outcomes were studied. EA with distal tracheoesophageal fistula (TEF) was the commonest type with 58/86 (67%). The percentage of patients with at least one associated anomaly was 52/86 (60%), with 7/86 (8%) who are from consanguineous parent...
Source: Diseases of the Esophagus - January 28, 2014 Category: Gastroenterology Authors: D. Bouguermouh, A. Salem Tags: Original article Source Type: research

Alternations in genes expression of pathway signaling in esophageal tissue with atresia: results of expression microarray profiling
Summary Esophageal atresia (EA) is a congenital defect of the esophagus involving the interruption of the esophagus with or without connection to the trachea (tracheoesophageal fistula [TEF]). EA/TEF may occur as an isolated anomaly, may be part of a complex of congenital defects (syndromic), or may develop within the context of a known syndrome or association. The molecular mechanisms underlying the development of EA are poorly understood. It is supposed that a combination of multigenic factors and epigenetic modification of genes play a role in its etiology. The aim of our work was to assess the human gene expression mic...
Source: Diseases of the Esophagus - January 27, 2014 Category: Gastroenterology Authors: R. Smigiel, A. Lebioda, M. Blaszczyński, K. Korecka, P. Czauderna, W. Korlacki, A. Jakubiak, D. Bednarczyk, H. Maciejewski, P. Wizinska, M. M. Sasiadek, D. Patkowski Tags: Original Article Source Type: research

Congenital esophageal stenosis associated with esophageal atresia
Summary Congenital esophageal stenosis (CES) is a rare clinical condition but is frequently associated with esophageal atresia (EA). The aim of this study is to report the diagnosis, management, and outcome of CES associated with EA. Medical charts of CES‐EA patients from Lille University Hospital, Sainte‐Justine Hospital, and Montreal Children's Hospital were retrospectively reviewed. Seventeen patients (13 boys) were included. The incidence of CES in patients with EA was 3.6%. Fifteen patients had a type C EA, one had a type A EA, and one had an isolated tracheoesophageal fistula. Seven patients had associated additi...
Source: Diseases of the Esophagus - January 22, 2014 Category: Gastroenterology Authors: F. McCann, L. Michaud, A. Aspirot, D. Levesque, F. Gottrand, C. Faure Tags: Original Article Source Type: research

Recurrent oesophageal cancer complicated by tracheo-oesophageal fistula: improved palliation by means of parallel tracheal and oesophageal stenting
CONCLUSIONS Endoscopic parallel stent implantation provides an easy and ubiquitous available technique for closure and palliation of tracheo-oesophageal fistula caused by recurrent oesophageal cancer. Immediate sealing of the fistula and relief of symptoms related to aspiration is achieved while hazardous operations are avoided. Therefore, we recommend endoscopic parallel stent insertion as the treatment of choice in case of tracheo-oesophageal fistula caused by recurrent oesophageal cancer. (Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - January 17, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Schweigert, M., Posada-Gonzalez, M., Dubecz, A., Ofner, D., Muschweck, H., Stein, H. J. Tags: Thoracic Source Type: research

Recurrent esophagopericardial fistula in a patient with human immunodeficiency virus
We present a case of esophagopericardial fistula associated with Candida esophagitis in a patient with advanced human immunodeficiency virus (HIV) infection. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - January 16, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Lloyd M. Felmly, Walter F. DeNino, Chadrick E. Denlinger Tags: Online Only: Case Reports Source Type: research

Management of a congenital tracheoesophageal fistula in a young Spanish water dog
Conclusions: Contrast material swallow study using fluoroscopy was the most reliable diagnostic method. Bronchoscopy may allow the fistula to be visualized, but due to a small fistular opening it can lead to a false negative result. Surgical correction by ligation and dividing of the fistula suggests a good prognosis for early diagnosed and operated TEF. (Source: BMC Veterinary Research - Latest articles)
Source: BMC Veterinary Research - Latest articles - January 14, 2014 Category: Veterinary Research Authors: Pia KaminenSanna ViitanenAnu LappalainenAnja KiparMinna RajamäkiOuti Laitinen-Vapaavuori Source Type: research

Morbidity and Mortality in Patients with Esophageal Atresia – A Multi-Institutional Cohort Study
Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) is a rare congenital anomaly associated with significant morbidity and mortality. Previous studies are limited to retrospective institutional experiences. The purpose of this study was to provide national estimates of population characteristics, associated comorbidities, and outcomes with EA/TEF. (Source: Journal of Surgical Research)
Source: Journal of Surgical Research - January 11, 2014 Category: Surgery Authors: J.P. Sulkowski, J.N. Cooper, J.J. Lopez, Y. Jadcherla, A. Cuenot, K.J. Deans, P.C. Minneci Tags: ORAL SESSION: WEDNESDAY 2/5 7:30 - 9:30 AM Source Type: research

A Nationwide Analysis of Clinical Outcomes among Newborns with Esophageal Atresia and Tracheoesophageal Fistulas
(Source: Journal of Surgical Research)
Source: Journal of Surgical Research - January 11, 2014 Category: Surgery Authors: B. Wang, B.J. Allan, J. Tashiro, P.P. Parikh, E.A. Perez, A.R. Hogan, H.L. Neville, J.E. Sola Tags: QUICKSHOT SESSION: TUESDAY 2/4 7:30 - 9:30 AM Source Type: research

Structural and numerical changes of chromosome X in patients with esophageal atresia
boel & Annelies de Klein (Source: European Journal of Human Genetics)
Source: European Journal of Human Genetics - January 8, 2014 Category: Genetics & Stem Cells Authors: Erwin BrosensElisabeth M de JongTahsin Stefan BarakatBert H EussenBarbara D'haeneElfride De BaereHannah VerdinPino J PoddigheRobert-Jan GaljaardJoost GribnauAlice S BrooksDick TibboelAnnelies de Klein Tags: esophageal atresia tracheoesophageal fistula triple X syndrome SHOX duplication VACTERL association Source Type: research

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Anastomotic strictures (ASs) complicate the postoperative course of roughly one-third of all patients with esophageal atresia with or without tracheoesophageal fistula. Its development is multifactorial, but is due in part to tension on the anastomosis, gastroesophageal reflux disease, and the presence of a leak in the early postoperative period. Efforts at reducing the rate of AS have been largely unsuccessful, although meticulous technique and aggressive acid suppression remain the cornerstones of perioperative care. Once an AS has been confirmed the first-line treatment remains a course of esophageal dilatation. Adjunct...
Source: Journal of Pediatric Surgery - January 1, 2014 Category: Surgery Authors: Thomas Angerpointner Tags: International Abstracts of Pediatric Surgery Source Type: research

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Iatrogenic perforation of the neonate's pharynx and esophagus with normal anatomy was first described by Eklöf et al in 1968. It typically occurs in severely premature neonates who have undergone repeated traumatic attempts at endotracheal intubation or passage of orogastric tubes. It may also mimic esophageal atresia (EA). Perforation of upper pouch in tracheoesophageal fistula with EA was rarely reported. The authors report on a 1,400g (32weeks) neonate with pure EA and iatrogenic perforation of upper pouch due to use of catheter for diagnostic radiography. Postoperative course was uneventful. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - January 1, 2014 Category: Surgery Authors: Thomas Angerpointner Tags: International Abstracts of Pediatric Surgery Source Type: research

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A 2-day-old preterm female neonate weighing 1.6kg and having excessive frothing from mouth was investigated for suspected esophageal atresia and tracheoesophageal fistula. X-ray findings of an unusually low-ending upper pouch (up to T8 level) and the absence of gas in abdomen lead to suspicion of an unusual variety of esophageal atresia. Hence unlike the usual management of pure esophageal atresia, in terms of esophagostomy and gastrostomy in the neonatal period, right thoracotomy was performed allowing successful primary anastomosis. A high index of suspicion on the basis of radiological picture led to early diagnosis of ...
Source: Journal of Pediatric Surgery - January 1, 2014 Category: Surgery Authors: Thomas Angerpointner Tags: International Abstracts of Pediatric Surgery Source Type: research

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Repair of recurrent tracheoesophageal fistulas (rTEFs) remains a technically challenging endeavor. Although considered the gold standard, open surgical repair is associated with significant morbidity and rates of recurrence. Over the last 40years, endoscopic techniques have gained popularity and been touted as a safer first line treatment. This review compiles the published articles related to endoscopic repair of rTEFs and reports the various techniques, number of interventions, and success rates. Controversy will remain as to which technique is superior until prospective, multi-institutional studies are performed. (Sourc...
Source: Journal of Pediatric Surgery - January 1, 2014 Category: Surgery Authors: Thomas Angerpointner Tags: International Abstracts of Pediatric Surgery Source Type: research

Predictive factors for complications in children with esophageal atresia and tracheoesophageal fistula
The objective of this study was to describe the incidence of complications in children with esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) at a tertiary pediatric hospital and to identify predictive factors for their occurrence. A retrospective chart review of 110 patients born in or transferred to Sydney Children's Hospital with EA/TEF between January 1999 and December 2010 was done. Univariate and multivariate regression analyses were performed to identify predictive factors for the occurrence of complications in these children. From univariate analysis, early esophageal stricture formation was m...
Source: Diseases of the Esophagus - January 1, 2014 Category: Gastroenterology Authors: R. Shah, V. Varjavandi, U. Krishnan Tags: Original Article Source Type: research

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The authors reviewed the available literature on the role of minimally invasive techniques for esophageal atresia (EA)/tracheoesophageal fistula (TEF) repair. No prospective studies have been published to date. According to the recent classification of the Oxford Centre for evidence-based Medicine, the best available evidence for studies comparing the minimally invasive versus open approach for EA/TEF repair is Level 3 (a, b). Similar postoperative results of the thoracoscopic versus conventional repair are confirmed in four retrospective comparative studies and one meta-analysis. However, the available data on complicatio...
Source: Journal of Pediatric Surgery - January 1, 2014 Category: Surgery Authors: Thomas Angerpointner Tags: International Abstracts of Pediatric Surgery Source Type: research

Chronic cervical esophageal foreign bodies in children: surgical approach after unsuccessful endoscopic management.
CONCLUSIONS: A high index of suspicion is required to recognize CCEFBs in children with respiratory distress. Although endoscopic management remains the first-line treatment, it may fail or may not be possible because of transmural FB migration. In this setting, neck exploration with FB removal is a safe and effective alternative. PMID: 24574419 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - January 1, 2014 Category: ENT & OMF Authors: Schramm JC, Sewell RK, Azarow KS, Raynor SC, Abdessalam SF Tags: Ann Otol Rhinol Laryngol Source Type: research

Transtracheal approach to repair of a tracheo‐colonic fistula 44 years after colonic interposition
Conclusion: Tracheocolonic fistula is an extremely rare pathology, and the scarring that develops following prior esophagectomy makes a traditional lateral approach very difficult. The transtracheal approach is an effective method to obtain needed exposure in order to carry out the repair. Head Neck, 2013 (Source: Head and Neck)
Source: Head and Neck - December 26, 2013 Category: ENT & OMF Authors: Saral Mehra, Sophie Scherl, Cathy Lazarus, Eliza Dewey, Mark L. Urken Tags: Case Report Source Type: research

Analysis of cardiac anomalies in VACTERL association
CONCLUSIONAlthough this study does not, by design, provide further evidence toward the questions of whether CHD is a defining feature of VACTERL association, the frequency of CHD in our cohort does lend support to it being an important medical consideration in patients with VACTERL association. Based on our experience, we strongly recommend a screening echocardiogram to evaluate for CHD in individuals with a potential diagnosis of VACTERL association. Birth Defects Research (Part A) 97:792–797, 2013. © 2013 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - December 17, 2013 Category: Perinatology & Neonatology Authors: Bridget K. Cunningham, Donald W. Hadley, Hwaida Hannoush, Andrew C. Meltzer, Nickie Niforatos, Daniel Pineda‐Alvarez, Vandana Sachdev, Nicole Warren‐Mora, Benjamin D. Solomon Tags: Research Article Source Type: research

Free radial forearm flap in head and neck: Our experience.
CONCLUSIONS: Reconstructive surgery currently plays an important role in surgery for head and neck cancer. The radial forearm flap is a safe, reliable method for reconstruction of most defects in the ENT field. This type of intervention provides greater autonomy and safety in surgical oncology. PMID: 24342698 [PubMed - as supplied by publisher] (Source: Acta Otorrinolaringologica Espanola)
Source: Acta Otorrinolaringologica Espanola - December 13, 2013 Category: ENT & OMF Authors: Tornero J, Cruz-Toro P, Farré A, Vega-Celiz J, Skufca J, Nogués J, Maños-Pujol M Tags: Acta Otorrinolaringol Esp Source Type: research

An Approach to the Identification of Anomalies and Etiologies in Neonates with Identified or Suspected VACTERL (Vertebral Defects, Anal Atresia, Tracheo-Esophageal Fistula with Esophageal Atresia, Cardiac Anomalies, Renal Anomalies, and Limb Anomalies) Association
VATER association was first described in the early 1970s as the nonrandom co-occurrence of congenital malformations including vertebral defects, anal atresia, tracheo-esophageal fistula (TEF) with or without esophageal atresia (EA), and radial and renal dysplasia. Following initial reports, it was suggested that “V” should include vascular anomalies (including single umbilical artery). Cardiac malformations (“C”) and limb (“L”) anomalies other than radial anomalies were also added, such that the term “VACTERL” became the most common descriptor, despite variable evidence for the inclusion of features such as...
Source: The Journal of Pediatrics - December 13, 2013 Category: Pediatrics Authors: Benjamin D. Solomon, Linda A. Baker, Kelly A. Bear, Bridget K. Cunningham, Philip F. Giampietro, Colleen Hadigan, Donald W. Hadley, Steven Harrison, Marc A. Levitt, Nickie Niforatos, Scott M. Paul, Cathleen Raggio, Heiko Reutter, Nicole Warren-Mora Tags: Medical Progress Source Type: research

Surgical intervention for esophageal atresia in patients with trisomy 18
ABSTRACT Trisomy 18 is a common chromosomal aberration syndrome involving growth impairment, various malformations, poor prognosis, and severe developmental delay in survivors. Although esophageal atresia (EA) with tracheoesophageal fistula (TEF) is a potentially fatal complication that can only be rescued through surgical correction, no reports have addressed the efficacy of surgical intervention for EA in patients with trisomy 18. We reviewed detailed clinical information of 24 patients with trisomy 18 and EA who were admitted to two neonatal intensive care units in Japan and underwent intensive treatment including surgi...
Source: American Journal of Medical Genetics Part A - December 5, 2013 Category: Genetics & Stem Cells Authors: Eriko Nishi, Shigeru Takamizawa, Kenji Iio, Yasumasa Yamada, Katsumi Yoshizawa, Tomoko Hatata, Takehiko Hiroma, Seiji Mizuno, Hiroshi Kawame, Yoshimitsu Fukushima, Tomohiko Nakamura, Tomoki Kosho Tags: Research Article Source Type: research

Validation of measures from a thoracoscopic esophageal atresia/tracheoesophageal fistula repair simulator
Abstract: Purpose: A validated high fidelity simulation model would provide a safe environment to teach thoracoscopic EA/TEF repair to novices. The study purpose was to evaluate validity evidence for performance measures on an EA/TEF simulator.Methods: IRB-exempt data were collected from 12 self-reported “novice” and 8 “experienced” pediatric surgeons. Participants evaluated the EA/TEF repair simulator using survey ratings that were analyzed for test content validity evidence. Additionally, deidentified operative performances were videotaped and independently rated by two surgeons using the Objective Structured Ass...
Source: Journal of Pediatric Surgery - December 2, 2013 Category: Surgery Authors: Katherine A. Barsness, Deborah M. Rooney, Lauren M. Davis, Anthony C. Chin Tags: APSA Papers Source Type: research

TACRD and VACTERL associations in a fetus: Case report and review of the literature
We report the case of a male fetus with complete agenesis of the trachea and a tracheoesophageal fistula arising from the esophagus that connected through the carina, as well as several abnormalities (congenital cardiac abnormalities, duodenal atresia, vertebral defects, anal atresia, renal defects, limb defects, and diaphragmatic hernia). To our knowledge, few cases of infants with VACTERL or TACRD association have been reported to date. Here, we report a new case of a fetus that showed the full range of VACTERL and TACRD associations. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - December 1, 2013 Category: ENT & OMF Authors: Gan-qiong Xu, Qi-chang Zhou, Ming Zhang, Da-rong Pu, Zhu Ouyang Tags: Case reports Source Type: research

Oesophageal atresia
Abstract: Oesophageal atresia is a congenital malformation that affects approximately 1 in 4000 newborn infants. It is most commonly associated with a distal tracheo-oesophageal fistula. It can also be associated with vertebral anomalies, anorectal malformation, cardiac defects, renal and limb anomalies. It requires surgery, usually within the first day of life to correct the anomaly and establish continuity of the gastrointestinal tract. (Source: Surgery (Medicine Publishing))
Source: Surgery (Medicine Publishing) - December 1, 2013 Category: Surgery Authors: Gareth P. Hosie, Elizabeth Gavens Tags: Paediatric surgery II Source Type: research

A rare variant of esophageal atresia: Esophageal atresia with muscular continuity and upper pouch fistula.
Abstract To the Editor, Pure esophageal atresia (PEA) is characterized by a long segment between the esophageal pouches without tracheoesophageal fistula (TEF). Here, we present a very rare case of esophageal atresia (EA) in which the two blind pouches were connected by an atretic segment and proximal TEF was observed. A girl baby was born with a birth weight of 1970 g. Radiologic diagnosis of PEA was made by detecting a blind pouch of the proximal esophagus and the gasless abdomen. A gastrostomy was made. At 4 weeks of age, the patient underwent thoracotomy. It was observed that both ends of the esophagus were con...
Source: The Turkish Journal of Gastroenterology - December 1, 2013 Category: Gastroenterology Authors: Duman L, Savaş C, Büyükyavuz I, Karahan N, Akçam M, Melikoğlu M Tags: Turk J Gastroenterol Source Type: research

Oesophageal atresia with tracheoesophageal fistula and anal atresia in a patient with a de novo microduplication in 17q12.
We described a patient with a 1.4 Mb duplication at 17q12 detected by SNP-array study and validated using qRT-PCR, who presented with an oesophageal atresia accompanied with tracheoesophageal fistula and anal atresia as well as other symptoms resembling VATER association (thumb hypoplasia, sacral bone defect, cryptorchidism). Genomic rearrangements of chromosome 17q12 are associated with a variety of clinical phenotypes. Only few cases with OA patients with the duplication in 17q12 have been reported. The 17q12 region comprised 15 genes. We propose to consider a role for selected genes such as AATF (cell proliferation and...
Source: European Journal of Medical Genetics - November 12, 2013 Category: Genetics & Stem Cells Authors: Smigiel R, Marcelis C, Patkowski D, de Leeuw N, Bednarczyk D, Barg E, Mascianica K, Maria Sasiadek M, Brunner H Tags: Eur J Med Genet Source Type: research

Treatment of Malignant Tracheoesophageal Fistula
This article addresses the treatment of malignant enterorespiratory fistulas, especially malignant tracheoesophageal fistula (mTEF). mTEF typically occurs after radiochemotherapy for advanced esophageal cancer. Life expectancy is measured in months after successful treatment, and in days to weeks with a persistent fistula. To stop repeated episodes of aspiration and septic pneumonia, single or double stenting of the esophagus and trachea with self-expandable coated stents is the established palliative treatment. The indications, techniques, and pitfalls of esophageal and tracheal stenting are described. Surgical interventi...
Source: Thoracic Surgery Clinics - November 11, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Martin Hürtgen, Sascha C.A. Herber Source Type: research

VACTERL (Vertebral Defects, Anal Atresia, Tracheoesophageal Fistula with Esophageal Atresia, Cardiac Defects, Renal and Limb Anomalies) Association: Disease Spectrum in 25 Patients Ascertained for Their Upper Limb Involvement
Conclusion: Upper limb involvement in VACTERL association is a specific feature of the radial axis that occurs in monolateral form in approximately 75% of cases and, when bilateral, always occurs in a nonsymmetrical fashion. Odontoid and coccygeal hypoplasia and sacral dimple are newly reported malformations of the VACTERL phenotype. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - November 11, 2013 Category: Pediatrics Authors: Diana Carli, Lorenzo Garagnani, Mario Lando, Tracy Fairplay, Sergio Bernasconi, Antonio Landi, Antonio Percesepe Tags: Original Articles Source Type: research

Esophageal Bypass Operation Prior to Definitive Chemoradiotherapy in Advanced Esophageal Cancer With Tracheobronchial Invasion.
CONCLUSIONS: Esophageal bypass surgery prior to definitive chemoradiotherapy could be performed safely, and this strategy contributed to long-term survival in the patients who achieved a good response to chemoradiotherapy but developed an ERF. PMID: 24200399 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - November 5, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Hihara J, Hamai Y, Emi M, Aoki Y, Taomoto J, Miyata Y, Okada M Tags: Ann Thorac Surg Source Type: research

A standardised investigative strategy prior to revisional oesophageal surgery in children: High incidence of unexpected findings
Conclusions: This standardised approach for this complex group of patients reveals a high incidence of unexpected anatomical and functional anomalies with significant surgical and possible medico-legal implications. We recommend these investigations during the pre-operative work-up prior to all revisional oesophageal surgery. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - November 1, 2013 Category: Surgery Authors: Nigel J. Hall, Michelle Wyatt, Joe I. Curry, Edward M. Kiely Tags: Original Articles Source Type: research

Mandibulofacial dysostosis (Treacher‐Collins syndrome) in the fetus: Novel association with pectus carinatum in a molecularly confirmed case and review of the fetal phenotype
CONCLUSIONTreacher Collins syndrome can be prenatally detected by ultrasound and should be included in the wide range of genetic syndromes that can be diagnosed at perinatal autopsy. Affected fetuses tend to have a more severe phenotype than living patients. The reported association of Treacher Collins syndrome type 1 with pectus carinatum expands the phenotype, provides information on genotype–phenotype correlation, and suggests possible pathogenetic interactions between neural crest cell disorders and the formation of the sternum that merit investigation. Birth Defects Research (Part A), 2013. © 2013 Wiley Periodicals...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - November 1, 2013 Category: Perinatology & Neonatology Authors: Anastasia E. Konstantinidou, Iason Tassoulas, Georgios Kallipolitis, Spyros Gasparatos, Voula Velissariou, Helen Paraskevakou Tags: Research Article Source Type: research

Second study on the recurrence risk of isolated esophageal atresia with or without trachea‐esophageal fistula among first‐degree relatives: No evidence for increased risk of recurrence of EA/TEF or for malformations of the VATER/VACTERL association spectrum
CONCLUSIONIn contrast to previous studies, our results suggest a very low recurrence risk for isolated EA/TEF and/or for malformations of the VATER/VACTERL association spectrum among first‐degree relatives. Birth Defects Research (Part A), 2013. © 2013 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - November 1, 2013 Category: Perinatology & Neonatology Authors: Vera Choinitzki, Nadine Zwink, Enrika Bartels, Friederike Baudisch, Thomas M. Boemers, Alice Hölscher, Salmai Turial, Haitham Bachour, Andreas Heydweiller, Ralf Kurz, Peter Bartmann, Markus Pauly, Ulrike Brokmeier, Andreas Leutner, Markus M. Nöthen, Joh Tags: Original Research Article Source Type: research

Indications and outcomes of endoscopic CO2 laser cricopharyngeal myotomy
ConclusionsEndoscopic CO2 laser CPM is a safe treatment for cricopharyngeal dysfunction of various causes, though swallowing outcomes may vary depending on the surgical indication. Early feeding postoperatively after CPM is safe and facilitates early hospital discharge. Level of Evidence4. Laryngoscope, 2013 (Source: The Laryngoscope)
Source: The Laryngoscope - October 29, 2013 Category: ENT & OMF Authors: Jennifer L. Bergeron, Dinesh K. Chhetri Tags: Laryngology Source Type: research

Re: Secondary tracheo‐oesophageal fistula creation without rigid oesophagoscopy
(Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - October 24, 2013 Category: ENT & OMF Authors: A. Harrison, V. Visvanathan, K. Mackenzie Tags: Correspondence: Letters Source Type: research

Video demonstration of the rendezvous technique for the treatment of a malignant esophagorespiratory fistula
In conclusion, switching off the light source of 1 endoscope and trying to pass the guidewire from both directions may be useful in technically difficult cases. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - October 14, 2013 Category: Gastroenterology Authors: Georgios Mavrogenis, Dimitri Coumaros Tags: VideoGIE Source Type: research

A case for early bronchoscopic airway assessment after disc battery ingestion
We describe an interesting case of disc battery ingestion with delayed recognition of a TOF. We document the tracheal mucosal healing process of a large airway defect and describe the role of bronchoscopy in guiding the timing of surgical intervention. This case highlights the important role of early bronchoscopic assessment in management of these patients. Pediatr Pulmonol. © 2013 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - October 7, 2013 Category: Respiratory Medicine Authors: Danielle F. Wurzel, I. Brent Masters, Kelvin L. Choo, Alan F. Isles Tags: Case Report Source Type: research

Relationship Between Radiotherapy and Gastroesophageal Reflux Disease in Causing Tracheoesophageal Voice Rehabilitation Failure
The objective was to analyze the association of radiotherapy with gastroesophageal reflux as determinant of fistula related pathology, in voice prosthesis patients.Study Design: Retrospective study.Methods: Sixty-one laryngectomy patients were enrolled between 2005 and 2012. All patients underwent phonatory rehabilitation with voice prosthesis, along with evidence of gastroesophageal reflux disease, for which proton pump inhibitors (PPIs) were prescribed. We analyzed the occurrence of fistula-related problems among patients who received postoperative radiotherapy and those patients who did not.Results: We observed a higher...
Source: Journal of Voice - October 4, 2013 Category: ENT & OMF Authors: Salvatore Cocuzza, Marco Bonfiglio, Rita Chiaramonte, Agostino Serra Source Type: research

Concomitant Slide Tracheoplasty and Cardiac Operation for Congenital Tracheal Stenosis Associated With VACTERL.
Abstract The association of congenital tracheal stenosis and tracheoesophageal (TE) fistula is rare. Here, we report 2 patients with tracheobronchial stenosis (complete cartilage ring) involving the lower trachea and right bronchus. Both patients had associated VACTERL (vertebral anomalies, anal atresia, cardiovascular anomalies, TE, renal, and limb defects) congenital cardiac defects and tracheal diverticula after repair of the TE fistula in type C esophageal atresia. The stenotic segment began at the orifice of the TE fistula, which became diverticula after the TE fistula was repaired. Concomitant repair of conge...
Source: The Annals of Thoracic Surgery - October 1, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Wu ET, Wang CC, Lin MT, Huang PM, Chen SJ, Huang CH, Hwang HK, Chen MR, Huang SC Tags: Ann Thorac Surg Source Type: research

041 * surgery in pulmonary tuberculosis
Conclusions: Tuberculosis is essentially a medical disease; surgery comes into play only in special situations. (Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Santosham, R., Santosham, R. Tags: Non-Oncology I Source Type: research