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Health care-associated hepatitis C virus infection.
Abstract Hepatitis C virus (HCV) is a blood-borne pathogen that has a worldwide distribution and infects millions of people. Care-associated HCV infections represented a huge part of hepatitis C burden in the past via contaminated blood and unsafe injections and continue to be a serious problem of public health. The present review proposes a panorama of health care-associated HCV infections via the three mode of contamination that have been identified: (1) infected patient to non-infected patient; (2) infected patient to non-infected health care worker (HCW); and (3) infected HCW to non infected patient. For each c...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Pozzetto B, Memmi M, Garraud O, Roblin X, Berthelot P Tags: World J Gastroenterol Source Type: research

Locally advanced rectal cancer: The importance of a multidisciplinary approach.
Abstract Rectal cancer accounts for a relevant part of colorectal cancer cases, with a mortality of 4-10/100000 per year. The development of locoregional recurrences and the occurrence of distant metastases both influences the prognosis of these patients. In the last two decades, new multimodality strategies have improved the prognosis of locally advanced rectal cancer with a significant reduction of local relapse and an increase in terms of overall survival. Radical surgery still remains the principal curative treatment and the introduction of total mesorectal excision has significantly achieved a reduction in ter...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Berardi R, Maccaroni E, Onofri A, Morgese F, Torniai M, Tiberi M, Ferrini C, Cascinu S Tags: World J Gastroenterol Source Type: research

Early-onset colorectal cancer: A separate subset of colorectal cancer.
Abstract Colorectal cancer (CRC) has a great impact on the world population. With increasing frequency, CRC is described according to the presenting phenotype, based on its molecular characteristics. Classification of CRC tumors according to their genetic and/or epigenetic alterations is not only important for establishing the molecular bases of the disease, but also for predicting patient outcomes and developing more individualized treatments. Early-onset CRC is a heterogeneous disease, with a strong familial component, although the disease is sporadic in an important proportion of cases. Different molecular alter...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Silla IO, Rueda D, Rodríguez Y, García JL, de la Cruz Vigo F, Perea J Tags: World J Gastroenterol Source Type: research

Current status of function-preserving surgery for gastric cancer.
Abstract Recent advances in diagnostic techniques have allowed the diagnosis of gastric cancer (GC) at an early stage. Due to the low incidence of lymph node metastasis and favorable prognosis in early GC, function-preserving surgery which improves postoperative quality of life may be possible. Pylorus-preserving gastrectomy (PPG) is one such function-preserving procedure, which is expected to offer advantages with regards to dumping syndrome, bile reflux gastritis, and the frequency of flatus, although PPG may induce delayed gastric emptying. Proximal gastrectomy (PG) is another function-preserving procedure, whic...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Saito T, Kurokawa Y, Takiguchi S, Mori M, Doki Y Tags: World J Gastroenterol Source Type: research

Alternative splicing of DNA damage response genes and gastrointestinal cancers.
Abstract Alternative splicing, which is a common phenomenon in mammalian genomes, is a fundamental process of gene regulation and contributes to great protein diversity. Alternative splicing events not only occur in the normal gene regulation process but are also closely related to certain diseases including cancer. In this review, we briefly demonstrate the concept of alternative splicing and DNA damage and describe the association of alternative splicing and cancer pathogenesis, focusing on the potential relationship of alternative splicing, DNA damage, and gastrointestinal cancers. We will also discuss whether a...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Rahmutulla B, Matsushita K, Nomura F Tags: World J Gastroenterol Source Type: research

Genetic and phenotypic heterogeneity in tropical calcific pancreatitis.
Abstract Tropical calcific pancreatitis (TCP) is a form of chronic non-alcoholic pancreatitis initially reported in the developing parts of the tropical world. The clinical phenotype of TCP has undergone marked changes since its first description in 1968. The disease is now seen in relatively older people with less severe symptoms. In addition, there are varying reports on the proportion of cases presenting with imaging abnormalities like calcification, ductal dilation, and glandular atrophy. Significant progress has also been made in understanding the etiopathology of TCP. The role of malnutrition and cassava toxi...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Paliwal S, Bhaskar S, Chandak GR Tags: World J Gastroenterol Source Type: research

Oxidative stress and inflammatory signaling in cerulein pancreatitis.
Abstract Oxidative stress is considered to be an important regulator of the pathogenesis of acute pancreatitis. Reactive oxygen species (ROS) regulate the activation of inflammatory cascades, the recruitment of inflammatory cells and tissue damage in acute pancreatitis. A hallmark of the inflammatory response in pancreatitis is the induction of cytokine expression, which is regulated by a number of signaling molecules including oxidant-sensitive transcription factors such as nuclear factor-κB (NF-κB) and activator protein-1 (AP-1), signal transducer and activator of transcription 3 (STAT3), and mitogen-activated ...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Yu JH, Kim H Tags: World J Gastroenterol Source Type: research

Video capsule endoscopy: Perspectives of a revolutionary technique.
Abstract Video capsule endoscopy (VCE) was launched in 2000 and has revolutionized direct endoscopic imaging of the gut. VCE is now a first-line procedure for exploring the small bowel in cases of obscure digestive bleeding and is also indicated in some patients with Crohn's disease, celiac disease, and polyposis syndrome. A video capsule has also been designed for visualizing the esophagus in order to detect Barrett's esophagus or esophageal varices. Different capsules are now available and differ with regard to dimensions, image acquisition rate, battery life, field of view, and possible optical enhancements. Mor...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Bouchard S, Ibrahim M, Van Gossum A Tags: World J Gastroenterol Source Type: research

Computed tomography perfusion imaging as a potential imaging biomarker of colorectal cancer.
Abstract Neovascularization was reported to arise early in the adenoma-carcinoma sequence in colorectal cancer (CRC), and the importance of angiogenesis in cancer progression has been established. Computed tomography (CT) perfusion (CTP) based on high temporal resolution CT images enables evaluation of hemodynamics of tissue in vivo by modeling tracer kinetics. CTP has been reported to characterize tumor angiogenesis, and to be a sensitive marker for predicting recurrence or survival in CRC. In this review, we will discuss the biomarker value of CTP in the management of CRC patients. PMID: 25516645 [PubMed - as...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Hayano K, Fujishiro T, Sahani DV, Satoh A, Aoyagi T, Ohira G, Tochigi T, Matsubara H, Shuto K Tags: World J Gastroenterol Source Type: research

Anti-tumour necrosis factor agent and liver injury: Literature review, recommendations for management.
Abstract Abnormalities in liver function tests, including transient and self-limiting hypertransaminasemia, cholestatic disease and hepatitis, can develop during treatment with anti-tumour-necrosis-factor (TNF) therapy. The optimal management of liver injury related to anti-TNF therapy is still a matter of debate. Although some authors recommend discontinuing treatment in case of both a rise of alanine aminotransferase more than 5 times the upper limit of normal, or the occurrence of jaundice, there are no standard guidelines for the management of anti-TNF-related liver injury. Bibliographical searches were perform...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Rossi RE, Parisi I, Despott EJ, Burroughs AK, O'Beirne J, Conte D, Hamilton MI, Murray CD Tags: World J Gastroenterol Source Type: research

Hepatitis B and human immunodeficiency virus co-infection.
Abstract Hepatitis B and human immunodeficiency virus (HBV and HIV) infection share transmission patterns and risk factors, which explains high prevalence of chronic HBV infection in HIV infected patients. The natural course of HBV disease is altered by the HIV infection with less chance to clear acute HBV infection, faster progression to cirrhosis and higher risk of liver-related death in HIV-HBV co-infected patients than in HBV mono-infected ones. HIV infected patients with chronic hepatitis B should be counseled for liver damage and surveillance of chronic hepatitis B should be performed to screen early hepatoce...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Phung BC, Sogni P, Launay O Tags: World J Gastroenterol Source Type: research

Hematopoietic stem cell transplantation for non-malignant gastrointestinal diseases.
Abstract Both, autologous and allogeneic hematopoietic stem cell transplantation (HSCT) can be used to cure or ameliorate a variety of malignant and non-malignant diseases. The rationale behind this strategy is based on the concept of immunoablation using high-dose chemotherapy, with subsequent regeneration of naive T-lymphocytes derived from reinfused hematopoietic progenitor cells. In addition, the use of HSCT allows for the administration of high-dose chemotherapy (whether or not combined with immunomodulating agents such as antithymocyte globulin) resulting in a prompt remission in therapy-refractory patients. ...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Al-Toma A, Nijeboer P, Bouma G, Visser O, Mulder CJ Tags: World J Gastroenterol Source Type: research

Pea3 expression promotes the invasive and metastatic potential of colorectal carcinoma.
CONCLUSION: Our study implicates Pea3 as a mediator of metastases, and provides a biological rationale for the adverse prognosis associated with elevated Pea3 expression in human CRC. PMID: 25516649 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Mesci A, Taeb S, Huang X, Jairath R, Sivaloganathan D, Liu SK Tags: World J Gastroenterol Source Type: research

Epidemiology of upper gastrointestinal symptoms in Brazil (EpiGastro): A population-based study according to sex and age group.
CONCLUSION: Symptoms consistent with dyspepsia and GERD are prevalent in Brazil and represent major public-health and clinical challenges. PMID: 25516650 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: do Rosário Dias de Oliveira Latorre M, Medeiros da Silva A, Chinzon D, Eisig JN, Dias-Bastos TR Tags: World J Gastroenterol Source Type: research

Hybrid bioartificial liver support in cynomolgus monkeys with D-galactosamine-induced acute liver failure.
CONCLUSION: The novel hybrid bioartificial liver plays a significant role in liver support by significantly reducing serum biochemistry levels and extending animal survival time. PMID: 25516651 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Zhang Z, Zhao YC, Cheng Y, Jian GD, Pan MX, Gao Y Tags: World J Gastroenterol Source Type: research

Hepatoprotective effect of nitric oxide in experimental model of acute hepatic failure.
CONCLUSION: The endogenous NO pathway plays an important role in the development of experimental galactosamine-induced AHF. PMID: 25516652 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Saracyn M, Brytan M, Zdanowski R, Ząbkowski T, Dyrla P, Patera J, Wojtuń S, Kozłowski W, Wańkowicz Z Tags: World J Gastroenterol Source Type: research

T3-induced liver AMP-activated protein kinase signaling: Redox dependency and upregulation of downstream targets.
CONCLUSION: T3 administration activates liver AMPK signaling in a redox-dependent manner, leading to FAO enhancement as evidenced by the consequent ketogenic response, which may constitute a key molecular mechanism regulating energy dynamics to support T3 preconditioning against ischemia-reperfusion injury. PMID: 25516653 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Videla LA, Fernández V, Cornejo P, Vargas R, Morales P, Ceballo J, Fischer A, Escudero N, Escobar O Tags: World J Gastroenterol Source Type: research

Lobaplatin inhibits growth of gastric cancer cells by inducing apoptosis.
CONCLUSION: The cytotoxicity of lobaplatin may be due to its ability of inducing apoptosis of gastric cancer cells, which would support the potential use of lobaplatin for the therapy of gastric cancer. PMID: 25516654 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Yin CY, Lin XL, Tian L, Ye M, Yang XY, Xiao XY Tags: World J Gastroenterol Source Type: research

Oesophageal flap valvuloplasty and wrapping suturing prevent gastrooesophageal reflux disease in dogs after oesophageal anastomosis.
CONCLUSION: The oesophageal flap valvuloplasty and wrapping suturing technique can improve the postoperative quality of life through the long-term elimination of reflux oesophagitis and decreased stricture formation after primary oesophageal anastomosis. PMID: 25516655 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Dai JG, Liu QX, Den XF, Min JX Tags: World J Gastroenterol Source Type: research

miR-374b-5p suppresses RECK expression and promotes gastric cancer cell invasion and metastasis.
CONCLUSION: These findings indicate that upregulation of miR-374b-5p contributes to gastric cancer cell metastasis and invasion through inhibition of RECK expression. PMID: 25516656 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Xie J, Tan ZH, Tang X, Mo MS, Liu YP, Gan RL, Li Y, Zhang L, Li GQ Tags: World J Gastroenterol Source Type: research

Pancreaticoduodenectomy with vascular reconstruction for adenocarcinoma of the pancreas with borderline resectability.
CONCLUSION: The short-term and survival outcomes with simultaneous resection were not compromised when compared with that of standard pancreaticoduodenectomy. PMID: 25516657 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Cheung TT, Poon RT, Chok KSh, Chan AC, Tsang SH, Dai WC, Chan SC, Fan ST, Lo CM Tags: World J Gastroenterol Source Type: research

Case-control study of diabetes-related genetic variants and pancreatic cancer risk in Japan.
CONCLUSION: Our case-control study indicates that rs1501299 in the ADIPOQ gene may be associated with pancreatic cancer risk. These findings should be replicated in additional studies. PMID: 25516658 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Kuruma S, Egawa N, Kurata M, Honda G, Kamisawa T, Ueda J, Ishii H, Ueno M, Nakao H, Mori M, Matsuo K, Hosono S, Ohkawa S, Wakai K, Nakamura K, Tamakoshi A, Nojima M, Takahashi M, Shimada K, Nishiyama T, Kikuchi S, Lin Y Tags: World J Gastroenterol Source Type: research

Extraintestinal manifestations in a large series of Italian inflammatory bowel disease patients.
CONCLUSION: Mucocutaneous manifestations, arthritis Type 1 and uveitis were significantly more frequent in CD than UC. The complications of the musculoskeletal system were the mostly observed ones, often with symptoms more severe than intestinal ones, confirming the need for close cooperation with rheumatologists. PMID: 25516659 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Zippi M, Corrado C, Pica R, Avallone EV, Cassieri C, De Nitto D, Paoluzi P, Vernia P Tags: World J Gastroenterol Source Type: research

Outcome of endotherapy for pancreas divisum in patients with acute recurrent pancreatitis.
CONCLUSION: Patients with PDiv and recent episodes of AP can benefit from endoscopic therapy. Effective endotherapy may reduce the risk of developing EUS signs of CP at a rate similar to that seen in patients of previous RAP group, managed conservatively. However, in a subset of patients, endotherapy, although successful, did not prevent the evolution of endosonographic signs of CP. PMID: 25516660 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Mariani A, Di Leo M, Petrone MC, Arcidiacono PG, Giussani A, Zuppardo RA, Cavestro GM, Testoni PA Tags: World J Gastroenterol Source Type: research

Verification of gene expression profiles for colorectal cancer using 12 internet public microarray datasets.
CONCLUSION: A novel gene expression profile was associated with CRC and can potentially be applied to blood-based detection assays. PMID: 25516661 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Chang YT, Yao CT, Su SL, Chou YC, Chu CM, Huang CS, Terng HJ, Chou HL, Wetter T, Chen KH, Chang CW, Shih YW, Lai CH Tags: World J Gastroenterol Source Type: research

Prognostic factors for survival after transarterial chemoembolization combined with microwave ablation for hepatocellular carcinoma.
CONCLUSION: Superior performance status, MWA treatment and targeted drug were favorable factors, and large HCC, PVTT and advanced BCLC stage were risk factors for survival after TACE-MWA for HCC. PMID: 25516662 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Ni JY, Sun HL, Chen YT, Luo JH, Chen D, Jiang XY, Xu LF Tags: World J Gastroenterol Source Type: research

Analysis of risk factors for postoperative pancreatic fistula following pancreaticoduodenectomy.
CONCLUSION: A pancreatic duct diameter ≤ 3 mm is an independent risk factor for POPF. External stent drainage of pancreatic secretion may reduce CR-POPF mortality and POPF severity. PMID: 25516663 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Liu QY, Zhang WZ, Xia HT, Leng JJ, Wan T, Liang B, Yang T, Dong JH Tags: World J Gastroenterol Source Type: research

Genomic landscape of pancreatic neuroendocrine tumors.
CONCLUSION: This study suggests that several frequent CNAs in numerous candidate regions are involved in the pathogenesis and metastatic progression of PanNET. PMID: 25516664 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Gebauer N, Schmidt-Werthern C, Bernard V, Feller AC, Keck T, Begum N, Rades D, Lehnert H, Brabant G, Thorns C Tags: World J Gastroenterol Source Type: research

Endoscopic non-technical skills team training: The next step in quality assurance of endoscopy training.
CONCLUSION: A novel comprehensive training package addressing patient safety, non-technical skills and adverse event analysis was successful in improving multi-disciplinary teams' knowledge and safety attitudes. PMID: 25516665 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Matharoo M, Haycock A, Sevdalis N, Thomas-Gibson S Tags: World J Gastroenterol Source Type: research

Cytokine production in patients with cirrhosis and TLR4 polymorphisms.
CONCLUSION: TLR4 polymorphisms were associated with a distinctive pattern of cytokine production in cirrhotic patients, suggesting that they play a role in the development of cirrhosis complications. PMID: 25516666 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Nieto JC, Sánchez E, Román E, Vidal S, Oliva L, Guarner-Argente C, Poca M, Torras X, Juárez C, Guarner C, Soriano G Tags: World J Gastroenterol Source Type: research

Clinical epidemiology of ulcerative colitis in Arabs based on the Montréal classification.
CONCLUSION: The majority of UC cases were young people (17-40 years), with a male preponderance. While the disease course was found to be similar to that reported in Western countries, more similarities were found with Asian countries with regards to the extent of the disease and response to steroid therapy. PMID: 25516667 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Alharbi OR, Azzam NA, Almalki AS, Almadi MA, Alswat KA, Sadaf N, Aljebreen AM Tags: World J Gastroenterol Source Type: research

Plasma cathepsin L: A prognostic marker for pancreatic cancer.
CONCLUSION: Cathepsin L levels in plasma of pancreatic cancer patients may be used as a potential prognostic marker for the disease. PMID: 25516668 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Singh N, Das P, Gupta S, Sachdev V, Srivasatava S, Datta Gupta S, Pandey RM, Sahni P, Chauhan SS, Saraya A Tags: World J Gastroenterol Source Type: research

Significance of downregulation of liver fatty acid-binding protein in hepatocellular carcinoma.
CONCLUSION: In smaller HCC, L-FABP downregulation probably occurs because of phenotypic changes during tumor progression. Moreover, this downregulation correlated with tumor differentiation and intratumoral inflammation. PMID: 25516669 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Inoue M, Takahashi Y, Fujii T, Kitagawa M, Fukusato T Tags: World J Gastroenterol Source Type: research

Laterally spreading tumors: Limitations of computed tomography colonography.
CONCLUSION: The detection rate of LSTs by CTC, particularly the non-granular type was not acceptable. Practitioners should be aware of the relatively low detection rate when using CTC. PMID: 25516670 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Togashi K, Utano K, Kijima S, Sato Y, Horie H, Sunada K, Lefor AT, Sugimoto H, Yasuda Y Tags: World J Gastroenterol Source Type: research

Three-Tesla magnetic resonance elastography for hepatic fibrosis: Comparison with diffusion-weighted imaging and gadoxetic acid-enhanced magnetic resonance imaging.
CONCLUSION: MRE at 3-Tesla could be a feasible method for the assessment of hepatic fibrosis. PMID: 25516671 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Park HS, Kim YJ, Yu MH, Choe WH, Jung SI, Jeon HJ Tags: World J Gastroenterol Source Type: research

Upper-gastrointestinal bleeding secondary to peptic ulcer disease: Incidence and outcomes.
CONCLUSION: UGIB secondary to PUD, particularly duodenal ulcers, was associated with significant morbidity and mortality. Early readmissions increased over time and occurred more commonly in rural areas. PMID: 25516672 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Quan S, Frolkis A, Milne K, Molodecky N, Yang H, Dixon E, Ball CG, Myers RP, Ghosh S, Hilsden R, van Zanten SV, Kaplan GG Tags: World J Gastroenterol Source Type: research

Introducing an enhanced recovery after surgery program in colorectal surgery: A single center experience.
CONCLUSION: Our results confirm that introduction of an ERAS protocol for colorectal surgery allows quicker postoperative recovery and shortens the length of stay compared to historical series. PMID: 25516673 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Bona S, Molteni M, Rosati R, Elmore U, Bagnoli P, Monzani R, Caravaca M, Montorsi M Tags: World J Gastroenterol Source Type: research

Prevalence, histologic and clinical characteristics of heterotopic gastric mucosa in Chinese patients.
CONCLUSION: Clinical complaints should be considered to improve the detection rate of HMG. The prevalence of intestinal metaplasia and dysplasia also indicates a need for endoscopic follow-up. PMID: 25516674 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Fang Y, Chen L, Chen DF, Ren WY, Shen CF, Xu Y, Xia YJ, Li JW, Wang P, Zhang AR, Shao SZ, Yu XN, Peng GY, Fang DC Tags: World J Gastroenterol Source Type: research

Costs of laparoscopic and open liver and pancreatic resection: A systematic review.
CONCLUSION: This systematic review support the economic advantage of laparoscopic over open approach to liver and pancreatic resection. PMID: 25516675 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Limongelli P, Vitiello C, Belli A, Pai M, Tolone S, Del Genio G, Brusciano L, Docimo G, Habib N, Belli G, Jiao LR, Docimo L Tags: World J Gastroenterol Source Type: research

Effects of laparoscopic cholecystectomy on lung function: A systematic review.
CONCLUSION: Laparoscopic cholecystectomy seems to be associated with less postoperative derangement of lung function compared to the open procedure. PMID: 25516676 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Bablekos GD, Michaelides SA, Analitis A, Charalabopoulos KA Tags: World J Gastroenterol Source Type: research

Epidemiology of Helicobacter pylori infection among the healthy population in Iran and countries of the Eastern Mediterranean Region: A systematic review of prevalence and risk factors.
CONCLUSION: The prevalence of H. pylori in EMRO countries is still high in the healthy asymptomatic population. Strategies to improve sanitary facilities, educational status, and socioeconomic status should be implemented to minimize H. pylori infection. PMID: 25516677 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Eshraghian A Tags: World J Gastroenterol Source Type: research

Meta-analysis of laparoscopic vs open cholecystectomy in elderly patients.
CONCLUSION: Further high-quality evidence is necessary to draw definite conclusions, although best-available evidence supports the selective use of laparoscopy in this patient population. PMID: 25516678 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Antoniou SA, Antoniou GA, Koch OO, Pointner R, Granderath FA Tags: World J Gastroenterol Source Type: research

Helicobacter pylori infection and atopic diseases: Is there a relationship? A systematic review and meta-analysis.
CONCLUSION: There is some evidence of an inverse association between atopy/allergic diseases and H. pylori infection, although further studied are needed. PMID: 25516679 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Lionetti E, Leonardi S, Lanzafame A, Garozzo MT, Filippelli M, Tomarchio S, Ferrara V, Salpietro C, Pulvirenti A, Francavilla R, Catassi C Tags: World J Gastroenterol Source Type: research

Is concomitant radiotherapy necessary with gemcitabine-based chemotherapy in pancreatic cancer?
CONCLUSION: Radiotherapy is not beneficial with gemcitabine-based chemotherapy for PC. Further exploration for better radiotherapy approaches and therapeutic regimens for the treatment of PC is warranted. PMID: 25516680 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Zhang X, Huang HJ, Feng D, Yang DJ, Wang CM, Cai QP Tags: World J Gastroenterol Source Type: research

Late onset fulminant Wilson's disease: A case report and review of the literature.
In this report, we present a case of late onset fulminant WD in a 58-year-old patient in whom the diagnosis was established clinically, by genetic analysis of the ATP7B gene disclosing rare mutations (G1099S and c.1707+3insT) as well as by high hepatic copper content. We also reviewed the relevant literature. The diagnosis of WD with late onset presentation is easily overlooked. The diagnostic features and the genetic background in patients with late onset WD are not different from those in patients with early onset WD, except for the age. Effective treatments for this disorder that can be fatal are available and will prev...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Weitzman E, Pappo O, Weiss P, Frydman M, Haviv-Yadid Y, Ben Ari Z Tags: World J Gastroenterol Source Type: research

Rare combination of familial adenomatous polyposis and gallbladder polyps.
We present a case of a 60-year-old woman with familial adenomatous polyposis who presented with an elevated mass in the neck of the gallbladder (measuring 16 mm × 8 mm in diameter) and multiple small cholecystic polyps. She had undergone a total colectomy for ascending colon cancer associated with familial adenomatous polyposis 22 years previously. The patient underwent laparoscopic cholecystectomy under a preoperative diagnosis of multifocal gallbladder polyps. Pathologic examination of the resected gallbladder revealed more than 70 adenomatous lesions, a feature consistent with adenoma of the gallbladder. This case sugg...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Mori Y, Sato N, Matayoshi N, Tamura T, Minagawa N, Shibao K, Higure A, Nakamoto M, Taguchi M, Yamaguchi K Tags: World J Gastroenterol Source Type: research

Hirschsprung's disease in twin to twin transfusion syndrome: A case report.
We report on a 33(+6) gestational wk donor infant with TTTS who had intermittent obstructive episodes, including delayed meconium passage and colonic dilatation on abdominal X-ray. The diagnosis of Hirschsprung's disease was based on a lateral pelvic film with a reversed rectosigmoid ratio. A subsequent barium colon study and rectal suction biopsy indicated a short segment aganglionosis of the colon. PMID: 25516683 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Park HW, Cho MJ, Kim WY, Kwak BO, Kim MH Tags: World J Gastroenterol Source Type: research

Emergency laparoscopic partial splenectomy for ruptured spleen: A case report.
Abstract Splenic rupture is a common consequence of blunt abdominal trauma. Emergency splenectomy is indicated when conservative management is not effective. With better understanding of the immunologic function of the spleen, surgeons have begun to perform the splenic-preserving surgery. However, it is technical challenge to perform emergency laparoscopic partial splenectomy for patient with spleen rupture. A 15-year-old male patient suffered from grade III spleen injury basing on the American association for the surgery of trauma splenic injury scale. Conservative treatment failed to success basing on the dramati...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Cai YQ, Li CL, Zhang H, Wang X, Peng B Tags: World J Gastroenterol Source Type: research

Focal autoimmune pancreatitis and chronic sclerosing sialadenitis mimicking pancreatic cancer and neck metastasis.
Abstract Type 1 autoimmune pancreatitis (AIP) or chronic sclerosing sialadenitis (Küttner's tumour) is an uncommon disorder that has recently been confirmed as an IgG4-related disease. Here, we describe a rare case of a 53-year-old male patient who primarily presented with pancreatic body mass, left neck mass and several lumps in his lower lip mimicking pancreatic cancer (PC) and neck metastasis. The patient underwent pancreatic body mass and labial gland lumps resection as well as an ultrasound-guided biopsy of the left neck mass. He was diagnosed with IgG4-related focal type of AIP (f-AIP) and Küttner's tumour ...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Sun L, Zhou Q, Brigstock DR, Yan S, Xiu M, Piao RL, Gao YH, Gao RP Tags: World J Gastroenterol Source Type: research

Sclerosing cholangitis secondary to bleomycin-iodinated embolization for liver hemangioma.
This report retrospectively evaluated the diagnostic and therapeutic course of a patient with LDH who presented obstructive jaundice 6 years after TACE with BIO. Preoperative imaging identified a suspected malignant biliary stricture located at the convergence of the left and right hepatic ducts. Operative exploration demonstrated a full-thickness sclerosis of the hilar bile duct with right hepatic duct stricture and right lobe atrophy. Radical hepatic hilar resection with right-side hemihepatectomy and Roux-en-Y hepaticojejunostomy was performed because hilar cancer could not be excluded on frozen biopsy. Pathological res...
Source: World Journal of Gastroenterology : WJG - December 14, 2014 Category: Gastroenterology Authors: Jin S, Shi XJ, Sun XD, Wang SY, Wang GY Tags: World J Gastroenterol Source Type: research