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Iron deficiency anemia in celiac disease.
Abstract Iron is an important micronutrient that may be depleted in celiac disease. Iron deficiency and anemia may complicate well-established celiac disease, but may also be the presenting clinical feature in the absence of diarrhea or weight loss. If iron deficiency anemia occurs, it should be thoroughly evaluated, even if celiac disease has been defined since other superimposed causes of iron deficiency anemia may be present. Most often, impaired duodenal mucosal uptake of iron is evident since surface absorptive area in the duodenum is reduced, in large part, because celiac disease is an immune-mediated disorde...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Freeman HJ Tags: World J Gastroenterol Source Type: research

Oral Campylobacter species: Initiators of a subgroup of inflammatory bowel disease?
Abstract In recent years, a number of studies detected a significantly higher prevalence of Campylobacter species such as Campylobacter concisus (C. concisus) in intestinal biopsies and fecal samples collected from patients with inflammatory bowel disease (IBD) compared to controls. Most of these Campylobacter species are not of zoonotic origin but are human oral Campylobacter species. Bacterial species usually cause diseases in the location where they colonize. However, C. concisus and other oral Campylobacter species are associated with IBD occurring at the lower parts of the gastrointestinal tract, suggesting th...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Zhang L Tags: World J Gastroenterol Source Type: research

Treatment of hemorrhoids: A coloproctologist's view.
This article deals with some fundamental knowledge and current treatment of hemorrhoids in a view of a coloproctologist - which includes the management of hemorrhoids in complicated situations such as hemorrhoids in pregnancy, hemorrhoids in immunocompromised patients, hemorrhoids in patients with cirrhosis or portal hypertension, hemorrhoids in patients having antithrombotic agents, and acutely thrombosed or strangulated hemorrhoids. Future perspectives in the treatment of hemorrhoids are also discussed. PMID: 26309351 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Lohsiriwat V Tags: World J Gastroenterol Source Type: research

Lynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancer.
Abstract Hereditary non-polyposis colorectal cancer (HNPCC) was previously synonymous with Lynch syndrome; however, identification of the role of germline mutations in the DNA mismatch repair (MMR) genes has made it possible to differentiate Lynch syndrome from other conditions associated with familial colorectal cancer (CRC). Broadly, HNPCC may be dichotomized into conditions that demonstrate defective DNA MMR and microsatellite instability (MSI) vs those conditions that demonstrate intact DNA MMR. Conditions characterized by MMR deficient CRCs include Lynch syndrome (germline MMR mutation), Lynch-like syndrome (b...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Carethers JM, Stoffel EM Tags: World J Gastroenterol Source Type: research

Role of phytochemicals in colorectal cancer prevention.
Abstract Although the incidence of colorectal cancer (CRC) has been declining in recent decades, it remains a major public health issue as a leading cause of cancer mortality and morbidity worldwide. Prevention is one milestone for this disease. Extensive study has demonstrated that a diet containing fruits, vegetables, and spices has the potential to prevent CRC. The specific constituents in the dietary foods which are responsible for preventing CRC and the possible mechanisms have also been investigated extensively. Various phytochemicals have been identified in fruits, vegetables, and spices which exhibit chemop...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Li YH, Niu YB, Sun Y, Zhang F, Liu CX, Fan L, Mei QB Tags: World J Gastroenterol Source Type: research

Endoscopic full-thickness resection: Current status.
Abstract Conventional endoscopic resection techniques such as endoscopic mucosal resection or endoscopic submucosal dissection are powerful tools for treatment of gastrointestinal neoplasms. However, those techniques are restricted to superficial layers of the gastrointestinal wall. Endoscopic full-thickness resection (EFTR) is an evolving technique, which is just about to enter clinical routine. It is not only a powerful tool for diagnostic tissue acquisition but also has the potential to spare surgical therapy in selected patients. This review will give an overview about current EFTR techniques and devices. P...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Schmidt A, Meier B, Caca K Tags: World J Gastroenterol Source Type: research

Local excision by transanal endoscopic surgery.
Abstract Transanal endoscopic surgery (TES) consists of a series of anorectal surgical procedures using different devices that are introduced into the anal canal. TES has been developed significantly since it was first used in the 1980s. The key point for the success of these techniques is how accurately patients are selected. The main indication was the resection of endoscopically unresectable adenomas. In recent years, these techniques have become more widespread which has allowed them to be applied in conservative rectal procedures for both benign diseases and selected cases of rectal cancer. For more advanced r...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: García-Flórez LJ, Otero-Díez JL Tags: World J Gastroenterol Source Type: research

Perspectives in the treatment of pancreatic adenocarcinoma.
Abstract Pancreatic ductal adenocarcinoma (PDAC) is an incurable lethal disease whose incidence rate is growing. There is no effective screening for detection of early stage tumors and, in most cases, PDAC is diagnosed at advanced disease stages, when radical pancreatic resection is not possible. The aggressive nature of pancreatic tumor cells lies in the complex genetic mechanisms behind their uncontrolled capability to grow and metastasize, which involve essential adaptive changes in cellular metabolism, signaling, adhesion and immunoediting. In addition, PDAC cells promote a dense functional stroma that facilita...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Cid-Arregui A, Juarez V Tags: World J Gastroenterol Source Type: research

Reciprocal impact of host factors and Helicobacter pylori genotypes on gastric diseases.
CONCLUSION: The outcome of H. pylori infection is the result of interaction between bacterial genotypes and the age and sex of infected individuals. PMID: 26309357 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Honarmand-Jahromy S, Siavoshi F, Malekzadeh R, Nejad Sattari T, Latifi-Navid S Tags: World J Gastroenterol Source Type: research

Influence of the hTERT rs2736100 polymorphism on telomere length in gastric cancer.
CONCLUSION: The rs2736100 polymorphism of the hTERT gene is involved in the regulation of hTERT expression and telomere length, but not in the risk of gastric cancer. PMID: 26309358 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Choi BJ, Yoon JH, Kim O, Choi WS, Nam SW, Lee JY, Park WS Tags: World J Gastroenterol Source Type: research

MiR-30b suppresses tumor migration and invasion by targeting EIF5A2 in gastric cancer.
CONCLUSION: Our findings describe a link between miR-30b and EIF5A2, which plays an important role in mediating epithelial-mesenchymal transition. PMID: 26309359 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Tian SB, Yu JC, Liu YQ, Kang WM, Ma ZQ, Ye X, Yan C Tags: World J Gastroenterol Source Type: research

Linc00675 is a novel marker of short survival and recurrence in patients with pancreatic ductal adenocarcinoma.
CONCLUSION: Linc00675 may function as an oncogene during PDAC development, and its expression is an independent predictor of unfavorable prognosis in patients with PDAC. PMID: 26309360 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Li DD, Fu ZQ, Lin Q, Zhou Y, Zhou QB, Li ZH, Tan LP, Chen RF, Liu YM Tags: World J Gastroenterol Source Type: research

Mechanism of aqueous fructus aurantii immaturus extracts in neuroplexus of cathartic colons.
CONCLUSION: Aqueous FAI extracts and mosapride strengthen bowel movement in cathartic colons via increasing the expression of 5-HTR4 and neurofilament-H. PMID: 26309361 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Wang SY, Liu YP, Fan YH, Zhang L, Cai LJ, Lv B Tags: World J Gastroenterol Source Type: research

Fluid resuscitation in acute pancreatitis: Normal saline or lactated Ringer's solution?
CONCLUSION: Our study failed to find any evidence that the administration of RL in the first days of AP leads to improved clinical outcomes. PMID: 26309362 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Lipinski M, Rydzewska-Rosolowska A, Rydzewski A, Rydzewska G Tags: World J Gastroenterol Source Type: research

Colorectal stenting for palliation and as a bridge to surgery: A 5-year follow-up study.
CONCLUSION: The efficacy and safety of colonic stents was demonstrated both as a bridge to surgery and for palliative decompression. In addition, results emphasize the importance of the skills of the endoscopist in colonic stenting. PMID: 26309363 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Bayraktar B, Ozemir IA, Kefeli U, Demiral G, Sagiroğlu J, Bayraktar O, Adali G, Ozcelik A, Tortum OB Tags: World J Gastroenterol Source Type: research

Simple colonoscopy reporting system checking the detection rate of colon polyps.
CONCLUSION: We envision that KG quality reporting system can be applied to develop a comprehensive system to check colon polyp detection rates in other gastroenterology centers. PMID: 26309364 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Kim JH, Choi YJ, Kwon HJ, Park SJ, Park MI, Moon W, Kim SE Tags: World J Gastroenterol Source Type: research

Advantage of endoscopic mucosal resection with a cap for rectal neuroendocrine tumors.
CONCLUSION: EMR-C may be simple, faster, and more effective than ESD in removing rectal NETs and may be preferable for resection of small rectal NETs. PMID: 26309365 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Park SB, Kim HW, Kang DH, Choi CW, Kim SJ, Nam HS Tags: World J Gastroenterol Source Type: research

Safety validation of decision trees for hepatocellular carcinoma.
CONCLUSION: The Chinese consensus decision tree expands the indications for hepatic resection for HCC patients and does not increase the PHLF rate compared to the Swiss-Clavien and Tokyo University-Makuuchi decision trees. It would be a safe and effective algorithm for hepatectomy in patients with hepatocellular carcinoma. PMID: 26309366 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Wang XQ, Liu Z, Lv WP, Luo Y, Yang GY, Li CH, Meng XF, Liu Y, Xu KS, Dong JH Tags: World J Gastroenterol Source Type: research

High expression of CD11c indicates favorable prognosis in patients with gastric cancer.
CONCLUSION: High expression of CD11c decreased the risk of death and relapse, and may be regarded as an alternative indicator of favorable prognosis in patients with GC. PMID: 26309367 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Wang Y, Xu B, Hu WW, Chen LJ, Wu CP, Lu BF, Shen YP, Jiang JT Tags: World J Gastroenterol Source Type: research

Presence of c.3956delC mutation in familial adenomatous polyposis patients from Brazil.
CONCLUSION: Regardless of its origin, the c.3956delC mutation is a strong candidate biomarker of this hereditary cancer syndrome in families of northern Brazil. PMID: 26309368 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Moreira-Nunes CA, Alcântara DD, Lima-Júnior SF, Cavalléro SR, Rey JA, Pinto GR, de Assumpção PP, Burbano RR Tags: World J Gastroenterol Source Type: research

Robotic radiosurgery in pancreatic cancer: A systematic review.
CONCLUSION: RRS allows for local treatment in a shortened time (1 fraction) compared to traditional treatments (about 1 mo), providing the possibility for an easy integration with systemic therapies. Preliminary results did not show any outcome differences compared to standard chemoradiation. Thus, further efforts to reduce gastrointestinal toxicity are strongly needed. PMID: 26309369 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Buwenge M, Cellini F, Silvestris N, Cilla S, Deodato F, Macchia G, Mattiucci GC, Valentini V, Morganti AG Tags: World J Gastroenterol Source Type: research

Helicobacter pylori and gastric mucin expression: A systematic review and meta-analysis.
CONCLUSION: H. pylori inhibits MUC5AC expression in the gastric epithelium, and facilitates colonization. In contrast, increased MUC6 expression may help inhibiting colonization, using MUC6 antibiotics properties. PMID: 26309370 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Niv Y Tags: World J Gastroenterol Source Type: research

Adenocarcinoma of the third and fourth portions of the duodenum: The capsule endoscopy value.
CONCLUSION: Adenocarcinoma of the third and fourth portions of the duodenum is difficult to diagnose and capsule endoscopy is of great value. PMID: 26309371 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Paquissi FC, Lima AH, Lopes MF, Diaz FV Tags: World J Gastroenterol Source Type: research

Pancreatic paraganglioma with draining vessels.
Abstract A pancreatic paraganglioma is a rare neoplasm that is difficult to distinguish from a pancreatic neuroendocrine tumour. Here we present a case of pancreatic paraganglioma that was surgically resected following preoperative diagnosis of a pancreatic neuroendocrine tumour. Careful evaluation of the endoscopic ultrasonography findings revealed abundant draining vessels, which could have led to a correct preoperative diagnosis of pancreatic paraganglioma. PMID: 26309372 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Misumi Y, Fujisawa T, Hashimoto H, Kagawa K, Noie T, Chiba H, Horiuchi H, Harihara Y, Matsuhashi N Tags: World J Gastroenterol Source Type: research

Immunoglobulin G4-related autoimmune pancreatitis and sialadenitis: A case report.
Abstract Immunoglobulin G4 (IgG4)-related disease is a rare systemic diseases. A 67-year-old male presented at our institution with mild upper abdominal pain and jaundice for 20 d. Laboratory results revealed high levels of IgG4 (15.4 g/L, range: 0.08-1.4 g/L). Computed tomography (CT) showed significant enlargement of the entire pancreas and a capsule-like low-density rim surrounding the whole pancreas. Positron emission tomography/CT revealed increased uneven metabolism of the entire pancreas. Both magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography showed stenosis of th...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Fan RY, Sheng JQ Tags: World J Gastroenterol Source Type: research

Growth hormone used to control intractable bleeding caused by radiation-induced gastritis.
We describe a 69-year-old man with intractable hemorrhagic gastritis induced by postoperative radiotherapy for the treatment of esophageal carcinoma. Although anti-secretory therapy with or without octreotide was initiated for hemostasis over three months, melena still occurred off and on, and the patient required blood transfusions to maintain stable hemoglobin. Finally growth hormone was used in the treatment of hemorrhage for two weeks, and hemostasis was successfully achieved. This is the first report that growth hormone has been used to control intractable bleeding caused by radiation-induced gastritis. PMID: 2630...
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Zhang L, Xia WJ, Zhang ZS, Lu XL Tags: World J Gastroenterol Source Type: research

Signs and genetics of rare cancer syndromes with gastroenterological features.
Abstract Although the genetic bases of most hereditary cancer syndromes are known, and genetic tests are available for them, the incidence of the most rare of these syndromes is likely underestimated, partially because the clinical expression is neither fully understood nor easily diagnosed due to the variable and complex expressivity. The clinical features of a small pool of rare cancer syndromes include gastroenterological signs, though not necessarily tumors, that could require the intervention of a gastroenterologist during any of the phases of the clinical management. Herein we will attempt to spread the knowl...
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Bruno W, Fornarini G, Ghiorzo P Tags: World J Gastroenterol Source Type: research

Therapeutic potential of small interfering RNAs/micro interfering RNA in hepatocellular carcinoma.
Abstract Hepatocellular carcinoma (HCC) is the predominant form of primary liver cancer and represents the third leading cause of cancer-related death worldwide. Current available therapeutic approaches are poorly effective, especially for the advanced forms of the disease. In the last year, short double stranded RNA molecules termed small interfering RNAs (siRNAs) and micro interfering RNAs (miRNA), emerged as interesting molecules with potential therapeutic value for HCC. The practical use of these molecules is however limited by the identification of optimal molecular targets and especially by the lack of effect...
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Farra R, Grassi M, Grassi G, Dapas B Tags: World J Gastroenterol Source Type: research

Rectal cancer and Fournier's gangrene - current knowledge and therapeutic options.
Abstract Fournier's gangrene (FG) is a rapid progressive bacterial infection that involves the subcutaneous fascia and part of the deep fascia but spares the muscle in the scrotal, perianal and perineal region. The incidence has increased dramatically, while the reported incidence of rectal cancer-induced FG is unknown but is extremely low. Pathophysiology and clinical presentation of rectal cancer-induced FG per se does not differ from the other causes. Only rectal cancer-specific symptoms before presentation can lead to the diagnosis. The diagnosis of rectal cancer-induced FG should be excluded in every patient w...
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Bruketa T, Majerovic M, Augustin G Tags: World J Gastroenterol Source Type: research

Epigenetic regulation of DNA repair machinery in Helicobacter pylori-induced gastric carcinogenesis.
Abstract Although thousands of DNA damaging events occur in each cell every day, efficient DNA repair pathways have evolved to counteract them. The DNA repair machinery plays a key role in maintaining genomic stability by avoiding the maintenance of mutations. The DNA repair enzymes continuously monitor the chromosomes to correct any damage that is caused by exogenous and endogenous mutagens. If DNA damage in proliferating cells is not repaired because of an inadequate expression of DNA repair genes, it might increase the risk of cancer. In addition to mutations, which can be either inherited or somatically acquire...
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Santos JC, Ribeiro ML Tags: World J Gastroenterol Source Type: research

Outcome of stenting in biliary and pancreatic benign and malignant diseases: A comprehensive review.
Abstract Endoscopic stenting has become a widely method for the management of various malignant and benign pancreatico-biliary disorders. Biliary and pancreatic stents are devices made of plastic or metal used primarily to establish patency of an obstructed bile or pancreatic duct and may also be used to treat biliary or pancreatic leaks, pancreatic fluid collections and to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis. In this review, relevant literature search and expert opinions have been used to evaluate the outcome of stenting in biliary and pancreatic benign and malignant diseases. ...
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Mangiavillano B, Pagano N, Baron TH, Luigiano C Tags: World J Gastroenterol Source Type: research

Calcium glycerophosphate preserves transepithelial integrity in the Caco-2 model of intestinal transport.
CONCLUSION: It appears that CGP treatment might synergize with other therapies to preserve gut epithelial integrity. PMID: 26290632 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Datta P, Weis MT Tags: World J Gastroenterol Source Type: research

Female spontaneously diabetic Torii fatty rats develop nonalcoholic steatohepatitis-like hepatic lesions.
CONCLUSION: Female SDT fatty rats have the potential to become an important animal model of nonalcoholic steatohepatitis with type 2 diabetes and obesity. PMID: 26290633 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Ishii Y, Motohashi Y, Muramatsu M, Katsuda Y, Miyajima K, Sasase T, Yamada T, Matsui T, Kume S, Ohta T Tags: World J Gastroenterol Source Type: research

Protective effect of Salvia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharide-induced liver injury.
CONCLUSION: DHI may be a multi-function protectant against acute hepatic injury in mice through its anti-inflammatory, anti-oxidative and anti-apoptotic activities. PMID: 26290634 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Gao LN, Yan K, Cui YL, Fan GW, Wang YF Tags: World J Gastroenterol Source Type: research

Mechanisms of pyruvate kinase M2 isoform inhibits cell motility in hepatocellular carcinoma cells.
CONCLUSION: PKM2 play different roles in modulating the proliferation and metastasis of hepatocellular carcinoma cells, and this finding could help to guide the future targeted therapies. PMID: 26290635 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Chen YL, Song JJ, Chen XC, Xu W, Zhi Q, Liu YP, Xu HZ, Pan JS, Ren JL, Guleng B Tags: World J Gastroenterol Source Type: research

Endozepine-4 levels are increased in hepatic coma.
CONCLUSION: This study suggests that an increased level of endozepine in subjects with higher levels of MELD was observed. In conclusion, data concerning involvement of the GABA-ergic system in HE coma could be explained by stage-specific alterations. PMID: 26290636 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Malaguarnera G, Vacante M, Drago F, Bertino G, Motta M, Giordano M, Malaguarnera M Tags: World J Gastroenterol Source Type: research

Pre-lung transplant measures of reflux on impedance are superior to pH testing alone in predicting early allograft injury.
CONCLUSION: Pre-transplant MII measures of bolus reflux perform better than their pH-testing counterparts in predicting early allograft injury post-lung transplantation. PMID: 26290637 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Lo WK, Burakoff R, Goldberg HJ, Feldman N, Chan WW Tags: World J Gastroenterol Source Type: research

Diagnostic value of drain amylase for detecting intrathoracic leakage after esophagectomy.
CONCLUSION: Measurement of drain amylase levels is an inexpensive and easy tool that may be used to screen for anastomotic leakage soon after MI-ILE. However, clinical validation of this marker is necessary. PMID: 26290638 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Berkelmans GH, Kouwenhoven EA, Smeets BJ, Weijs TJ, Silva Corten LC, van Det MJ, Nieuwenhuijzen GA, Luyer MD Tags: World J Gastroenterol Source Type: research

Cardiac mucosa at the gastroesophageal junction: An Eastern perspective.
CONCLUSION: CM at the gastroesophageal junction is a common histologic finding in biopsy specimens, though not always present, and associated with gastroesophageal reflux disease and carditis severity. PMID: 26290639 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Kim A, Park WY, Shin N, Lee HJ, Kim YK, Lee SJ, Hwang CS, Park do Y, Kim GH, Lee BE, Jo HJ Tags: World J Gastroenterol Source Type: research

Predictors of the patency of self-expandable metallic stents in malignant gastroduodenal obstruction.
CONCLUSION: CEA levels can easily be measured at the time of stent placement and may help clinicians to predict stent patency and determine the appropriate stent procedure. PMID: 26290640 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Kim SH, Chun HJ, Yoo IK, Lee JM, Nam SJ, Choi HS, Kim ES, Keum B, Seo YS, Jeen YT, Lee HS, Um SH, Kim CD Tags: World J Gastroenterol Source Type: research

Full-thickness excision using transanal endoscopic microsurgery for treatment of rectal neuroendocrine tumors.
CONCLUSION: Full-thickness excision using TEM could be a first surgical option for complete removal of upper small rectal neuroendocrine tumors. PMID: 26290641 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Chen WJ, Wu N, Zhou JL, Lin GL, Qiu HZ Tags: World J Gastroenterol Source Type: research

Impact of a clinical pathway on treatment outcome in patients with acute pancreatitis.
CONCLUSION: The introduction of a CP has improved the treatment of patients with AP, as assessed by all of the observed parameters. PMID: 26290642 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Vujasinovic M, Makuc J, Tepes B, Marolt A, Kikec Z, Robac N Tags: World J Gastroenterol Source Type: research

Magnifying narrow-band imaging endoscopy is superior in diagnosis of early gastric cancer.
CONCLUSION: HD-WLE has a relatively high accuracy for diagnosing EGC and is an effective screening tool. Further investigations of ME and ME-NBI are required to achieve superior accuracy. PMID: 26290643 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Yu H, Yang AM, Lu XH, Zhou WX, Yao F, Fei GJ, Guo T, Yao LQ, He LP, Wang BM Tags: World J Gastroenterol Source Type: research

Effectiveness and safety of first-generation protease inhibitors in clinical practice: Hepatitis C virus patients with advanced fibrosis.
CONCLUSION: In a real clinical practice setting with a high proportion of patients with advanced fibrosis, effectiveness of first-generation PIs was high except for NR patients, with similar SVR rates being achieved by BOC and TVR. PMID: 26290644 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Salmerón J, Vinaixa C, Berenguer R, Pascasio JM, Sánchez Ruano JJ, Serra MÁ, Gila A, Diago M, Romero-Gómez M, Navarro JM, Testillano M, Fernández C, Espinosa D, Carmona I, Pons JA, Jorquera F, Rodriguez FJ, Pérez R, Montero JL, Granados R, Fernánde Tags: World J Gastroenterol Source Type: research

Peroral endoscopic myotomy for achalasia in patients aged ≥ 65 years.
CONCLUSION: POEM is a safe and effective technique for treatment of achalasia in patients aged ≥ 65 years, with improvement in symptoms and quality of life. PMID: 26290645 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Li CJ, Tan YY, Wang XH, Liu DL Tags: World J Gastroenterol Source Type: research

0.025-inch vs 0.035-inch guide wires for wire-guided cannulation during endoscopic retrograde cholangiopancreatography: A randomized study.
CONCLUSION: The thickness of the GW for WGC does not appear to affect either the success rate of selective bile duct cannulation or the incidence of PEP. PMID: 26290646 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Kitamura K, Yamamiya A, Ishii Y, Sato Y, Iwata T, Nomoto T, Ikegami A, Yoshida H Tags: World J Gastroenterol Source Type: research

Antioxidant therapy in acute, chronic and post-endoscopic retrograde cholangiopancreatography pancreatitis: An updated systematic review and meta-analysis.
CONCLUSION: While there is some evidence to support antioxidant therapy in AP, its effect on CP and PEP is still controversial. PMID: 26290647 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Gooshe M, Abdolghaffari AH, Nikfar S, Mahdaviani P, Abdollahi M Tags: World J Gastroenterol Source Type: research

Enhanced recovery after surgery programs in patients undergoing hepatectomy: A meta-analysis.
CONCLUSION: ERAS is a safe and effective program in liver surgery. Future studies should define the active elements to optimize postoperative outcomes for liver surgery. PMID: 26290648 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Ni TG, Yang HT, Zhang H, Meng HP, Li B Tags: World J Gastroenterol Source Type: research

Esophageal stenosis with sloughing esophagitis: A curious manifestation of graft-vs-host disease.
We report a case of a 56-year-old woman with a history of allogenic bone marrow transplantation for two years, complaining with dysphagia and weight loss. Upper endoscopy revealed esophageal stenosis and extensive mucosa sloughing. Biopsies confirmed the diagnosis of graft-vs-host disease (GVHD). Balloon dilation, corticosteroids and cyclosporin resulted in marked clinical improvement. Gastrointestinal tract is involved in the majority of patients with chronic GVHD. Esophageal manifestations are rare and include vesiculobullous disease, ulceration, esophageal webs, casts or strictures. Sloughing esophagitis along with seve...
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Trabulo D, Ferreira S, Lage P, Rego RL, Teixeira G, Pereira AD Tags: World J Gastroenterol Source Type: research

Esophageal intramural pseudodiverticulosis of the residual esophagus after esophagectomy for esophageal cancer.
Abstract A 91-year-old man was referred to our hospital with intermittent dysphagia. He had undergone esophagectomy for esophageal cancer (T3N2M0 Stage III) 11 years earlier. Endoscopic examination revealed an anastomotic stricture; signs of inflammation, including redness, erosion, edema, bleeding, friability, and exudate with white plaques; and multiple depressions in the residual esophagus. Radiographical examination revealed numerous fine, gastrografin-filled projections and an anastomotic stricture. Biopsy specimens from the area of the anastomotic stricture revealed inflammatory changes without signs of malig...
Source: World Journal of Gastroenterology : WJG - August 14, 2015 Category: Gastroenterology Authors: Takeshita N, Kanda N, Fukunaga T, Kimura M, Sugamoto Y, Tasaki K, Uesato M, Sazuka T, Maruyama T, Aida N, Tamachi T, Hosokawa T, Asai Y, Matsubara H Tags: World J Gastroenterol Source Type: research