Immunotherapy Stewardship Could Save Tens of Millions a Year Immunotherapy Stewardship Could Save Tens of Millions a Year
Weight-based dosing, dose rounding, and pharmacy-level vial sharing for immune checkpoint inhibitors could save the Veterans Health Administration more than $70 million annually.Medscape Medical News
Source: Medscape Allergy Headlines - July 13, 2023 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news

Positive Phase III results for Roche ’s OCREVUS (ocrelizumab) twice a year, 10-minute subcutaneous injection in patients with multiple sclerosis
Phase III OCARINA II trial met primary and secondary endpointsOCREVUS twice a year, 10-minute injection has the potential to further improve the treatment experience and expand OCREVUS usage in MS centres with IV capacity limitations or without IV infrastructureOCREVUS remains the first and only therapy approved for both RMS and PPMS, and more than 300,000 people have been treated globallyBasel, 13 July 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the Phase III OCARINA II trial evaluating OCREVUS ® (ocrelizumab) as a twice a year 10-minute subcutaneous injection met its primary and secondary endpoints in...
Source: Roche Media News - July 13, 2023 Category: Pharmaceuticals Source Type: news

Intranasal Delivery of a Next-Generation NDV-based, COVID-19 Booster...
The Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) in New York City is pleased to announce that CastleVax, Inc., has completed enrollment and a preliminary analysis of a phase 1 trial of...(PRWeb July 13, 2023)Read the full story at https://www.prweb.com/releases/intranasal_delivery_of_a_next_generation_ndv_based_covid_19_booster_vaccine_shows_promising_mucosal_and_systemic_immune_responses/prweb19441818.htm
Source: PRWeb: Medical Pharmaceuticals - July 13, 2023 Category: Pharmaceuticals Source Type: news

How the immune system can alter our behavior
Immune system recognition of allergens and pathogens in the environment allows the brain to take defensive measures, such as avoidance.
Source: Yale Science and Health News - July 12, 2023 Category: Universities & Medical Training Source Type: news

‘ Forever Chemical ’ Lawsuits Could Ultimately Eclipse the Big Tobacco Settlement
It was the dead cows on Wilbur Tennant’s farm that shaped most of Rob Bilott’s professional life. Tennant’s farm was located in Parkersburg, W. Va.; Bilott was—and remains—an environmental lawyer at the firm of Taft Stettinius & Hollister in Cincinnati. All had been well for Tennant until 1998, when half of his herd of 300 cows began to languish and die. The farmer and the lawyer never would have come together, but Bilott’s grandmother lived near Tennant, and a mutual friend suggested Tennant call her grandson for counsel. Tennant had reason to suspect he needed the help of an envir...
Source: TIME: Science - July 12, 2023 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized Environment healthscienceclimate Source Type: news

Malaysia arrests key 1MDB suspect linked to Jho Low
KUALA LUMPUR -- Malaysian authorities said on Wednesday that they had detained a former associate of fugitive Jho Low to assist in the investigation of massive corruption at state-owned investor 1MDB. Home Minister Saifuddin Nasution told reporters that Jasmine Loo, 50, was arrested on July 7 in…#kualalumpur #malaysian #jholow #saifuddinnasution #jasmineloo #interpol
Source: Reuters: Health - July 12, 2023 Category: Consumer Health News Source Type: news

US says it no longer deems Donald Trump immune from E. Jean Carroll lawsuit
Donald Trump suffered a legal defeat on Tuesday as the U.S. government reversed its earlier position that the former president could be immune from the writer E. Jean Carroll's $10 million defamation lawsuit against him. In a letter to Trump's and Carroll's lawyers, the U.S. Department of Justice…#donaldtrump #ejeancarroll #trump #carroll #manhattan #evidenceofmr #stevencheung #justicedepartment #robertakaplan #elle
Source: Reuters: Health - July 12, 2023 Category: Consumer Health News Source Type: news

Pharmacy-Level Stewardship Can Save on Immune Checkpoint Inhibitors
TUESDAY, July 11, 2023 -- Adoption of pharmacy-level stewardship strategies for immune checkpoint inhibitors could generate sizable reductions in spending for these drugs, according to a study published in the July issue of Health Affairs. Alex K....
Source: Drugs.com - Pharma News - July 11, 2023 Category: Pharmaceuticals Source Type: news

Yale team develops ‘MAJESTIC’ solution for future cancer cell therapies
Scientists have developed a new gene delivery and immune cell engineering technology with the potential to advance cell therapies for cancer and other diseases.
Source: Yale Science and Health News - July 11, 2023 Category: Universities & Medical Training Source Type: news

Some NSCLC Patients on ICI Therapy Fare Worse With Proton Pump Inhibitor Use
(MedPage Today) -- Proton pump inhibitor (PPI) use was independently associated with worse treatment outcomes in some patients with non-small cell lung cancer (NSCLC) on immune checkpoint inhibitor (ICI) therapy with pembrolizumab (Keytruda), according...
Source: MedPage Today Hematology/Oncology - July 11, 2023 Category: Hematology Source Type: news

The U.S. Scientist At the Heart of COVID-19 Lab Leak Conspiracies Is Still Trying to Save the World From the Next Pandemic
Ralph Baric stepped onto the auditorium stage at the University of North Carolina, Chapel Hill, and looked out at the sparse audience that had come to hear him speak. On the large projector screen hanging behind him, the following words appeared: How Bad the Next Pandemic Could Be, What Might It Look Like, and Will We be Ready. The date was May 29, 2018. “Well, I have to admit I’m a little worried about giving this talk,” Baric said. “The reason is being labelled a harbinger of doom.” The screen shifted, and images of the four horsemen of the apocalypse—Death, Famine, War, and Plague&mda...
Source: TIME: Health - July 11, 2023 Category: Consumer Health News Authors: Dan Werb Tags: Uncategorized COVID-19 feature freelance Source Type: news

Ghana: Boost Immune System Before Embarking On Hajj, Umrah - Dr Al-Hassan
[Ghanaian Times] A medical practitioner at the University of Ghana Hospital, Dr Abdul-Rahaman Al-Hassan, has advised pilgrims to Hajj and Umrah in Makkah, Saudi Arabia, to boost their immune system before embarking on such journey.
Source: AllAfrica News: Health and Medicine - July 11, 2023 Category: African Health Tags: Ghana Health and Medicine Religion West Africa Source Type: news

Event-related potential markers of suicidality in adolescents - Doruk Camsari D, Lewis CP, Sonmez AI, Ozger C, Fatih P, Yuruk D, Shekunov J, Vande Voort JL, Croarkin PE.
BACKGROUND: Implicit cognitive markers may assist with the prediction of suicidality beyond clinical risk factors. The aim of this study was to investigate neural correlates associated with Death/Suicide Implicit Association Test (DS-IAT) via event-related...
Source: SafetyLit - July 11, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

European Commission approves Roche ’s fixed-duration Columvi (glofitamab) for people with relapsed or refractory diffuse large B-cell lymphoma
Columvi is the first CD20xCD3 T-cell-engaging bispecific antibody available in Europe to treat the most common and aggressive form of lymphomaApproval is based on results from the phase I/II NP30179 study, where Columvi given as a fixed course induced early and long-lasting complete responses in people with heavily pre-treated or refractory diffuse large B-cell lymphoma1Columvi is given for a fixed period of time and made to be readily available, providing patients with a treatment end date and treatment-free periodBasel, 11 July 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the European Commission (EC) ha...
Source: Roche Media News - July 11, 2023 Category: Pharmaceuticals Source Type: news

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