‘Gold mine of unexplored biology’: Short protein sequences could dramatically expand human genome
The relatively small universe of human genes could grow by up to one-third, if a concerted effort to search for new genes that encode short proteins is successful. Many known miniproteins have already been shown to play key roles in cellular metabolism and disease, so the international effort to catalog new ones and determine their functions, announced last week in Nature Biotechnology , could shed light on a vast array of biochemical processes and provide targets for novel medicines. “The microproteome is a potential gold mine of unexplored biology,” says Eric Olson, a molecular biologist at the University ...
Source: ScienceNOW - July 21, 2022 Category: Science Source Type: news

UNISON-supported legal victory secures new holiday rights for all workers  
All workers in the UK will now receive the same minimum level of paid annual holiday leave, regardless of how many hours they work, following a landmark legal judgment by the Supreme Court today (Wednesday).   The case, Harpur Trust v Brazel & UNISON, was taken by music teacher Lesley Brazel. She argued her employer was wrong to give her fewer days of annual leave than the legal minimum because she only worked during the school term. UNISON got involved in the Brazel case because of its implications for thousands of school staff employed on term-time only contracts. The situation had previously been confused bec...
Source: UNISON Health care news - July 20, 2022 Category: UK Health Authors: Anthony Barnes Tags: News Press release annual leave term-time contracts Source Type: news

New Report Reveals That Medicare Part A Fund May Be Tapped Out By 2028, Triggering Calls for Congress to Address This Problem
Experts say it is time to change Medicare financing, even as large numbers of baby boomers continue to enroll in the program each year Medicare’s fund for payment of inpatient hospital care is expected to be tapped out in 2028. That’s according to a new report from Trustees of the Federal Hospital Insurance and Federal […] The post New Report Reveals That Medicare Part A Fund May Be Tapped Out By 2028, Triggering Calls for Congress to Address This Problem appeared first on Dark Daily.
Source: Dark Daily - July 18, 2022 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Coding, Billing, and Collections Laboratory Management and Operations Laboratory News Laboratory Resources Laboratory Testing 2022 Medicare Trustees Report 4Sight Health anatomic pathology Baby Boomers CDC centers for disease control a Source Type: news

Researchers in Japan Study Inhalable Gene Therapy for Mesothelioma
This study suggests that inhalable gene drugs are effective treatments for NSCLC and MPM,” the authors wrote. “These findings suggest that cancer gene therapy using inhalable drugs may constitute a novel therapeutic regimen and improve patients’ qualify of life owing to the low invasiveness of the mode of administration.” Effective, Noninvasive Treatment Is Rare Aggressive treatment for mesothelioma is hard on patients, and may lead to a significantly decreased quality of life. Major mesothelioma surgery can be physically overwhelming and its side effects long-lasting. Standard-of-care chemotherapy, the most ...
Source: Asbestos and Mesothelioma News - July 12, 2022 Category: Environmental Health Authors: Fran Mannino Tags: Clinical Trials/Research/Emerging Treatments Pleural Source Type: news

What is Prolonged Grief Disorder?
Discussion Grief is the process of experiencing different emotions, expressions and action in response to the death of someone the person cares about. This is a personal and private process. Grief can occur for other significant losses such as a divorce, job, or health. People may overlook loss of routine and special activities, presumed safety, and autonomy that can also cause loss and grief. Additional traumas of these loss types have been magnified especially in the past couple of years as the world lives with Covid. Mourning is a public process of showing grief. This often involves religious beliefs and customs, and cu...
Source: PediatricEducation.org - July 11, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Public Inspection: CMS: Medicare and Medicaid Programs: Calendar Year 2023 Payment Policies under the Physician Fee Schedule and Other Changes to Part B Payment Policies, Medicare Shared Savings Program Requirements, etc.
Pre-publication notice of proposed rule from the Centers for Medicare& Medicaid Services (CMS) making changes to the following: 1) Physician Fee Schedule and Medicare Part B payment policies; 2) Medicare Shared Savings Program requirements; 3) updates to the Quality Payment Program; 4) Medicare coverage of opioid use disorder services furnished by opioid treatment programs; 5) updates to certain Medicare and Medicaid provider enrollment policies; 6) updates to conditions of payment for DMEPOS suppliers; 7) coding and payment for wound care management product; and 8) requirements for electronic prescribing for controlled su...
Source: Federal Register updates via the Rural Assistance Center - July 8, 2022 Category: Rural Health Source Type: news

Janssen Announces U.S. FDA Breakthrough Therapy Designation Granted for Talquetamab for the Treatment of Relapsed or Refractory Multiple Myeloma
June 29, 2022 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) for talquetamab for the treatment of adult patients with relapsed or refractory multiple myeloma, who have previously received at least 4 prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 antibody. Talquetamab is an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting both GPRC5D, a novel drug target, on multiple myeloma cells and CD3 o...
Source: Johnson and Johnson - June 29, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Optellum touts NTAP eligibility for lung CT software
Artificial intelligence (AI) software developer Optellum said that its software’...Read more on AuntMinnie.comRelated Reading: AI aids CT lung screening by assessing suspicious lung nodules Optellum's Virtual Nodule Clinic receives CE Mark Coding changes that will impact radiology practices in 2022 Optellum teams up with Johnson & Johnson FDA clears Optellum's lung cancer diagnosis software
Source: AuntMinnie.com Headlines - June 28, 2022 Category: Radiology Source Type: news

Second annual audit of CVD PREVENT
National level recommendations for this second audit include a focus on restoring diagnosis, monitoring and management of hypertension, atrial fibrillation and high cholesterol to at least pre-pandemic levels, review of health inequalities and improvements in ethnicity coding.
Source: Current Awareness Service for Health (CASH) - June 28, 2022 Category: Consumer Health News Source Type: news

Community health worker activities in public health programs to prevent violence: coding roles and scope - Barbero C, Hafeedh Bin Abdullah A, Wiggins N, Garrettson M, Jones D, S Guinn A, Girod C, Bradford J, Wennerstrom A.
In multiple and related forms, violence is a serious public health issue with lasting impacts on health and wellness in the United States. Community health workers (CHWs) are frontline public health workers and trusted members of communities. We aimed to a...
Source: SafetyLit - June 27, 2022 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

The impact of crisis intervention team response, dispatch coding, and location on the outcomes of police encounters with individuals with mental illnesses in Chicago - Watson AC, Owens LK, Wood J, Compton MT.
This study aimed...
Source: SafetyLit - June 27, 2022 Category: International Medicine & Public Health Tags: Occupational Issues Source Type: news

Janssen Receives Positive CHMP Opinion for IMBRUVICA ® (ibrutinib) in a Fixed-Duration Combination Regimen for Adult Patients with Previously Untreated Chronic Lymphocytic Leukaemia (CLL)
BEERSE, BELGIUM, June 24, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion recommending approval of a new treatment option with IMBRUVICA® (ibrutinib) in an oral fixed-duration combination with venetoclax (I+V) for adults with previously untreated chronic lymphocytic leukaemia (CLL). Outcomes for patients with CLL have improved in the last decade with the advent of oral therapies that target the underlying disease biology.[1] This provides the opportunity...
Source: Johnson and Johnson - June 24, 2022 Category: Pharmaceuticals Source Type: news

PCR home testing for people eligible for COVID-19 treatments, UKHSA (updated 22nd June 2022)
If you ' re eligible for a coronavirus (COVID-19) treatment, follow this guide on how to do a PCR test at home and register your test kit. 22 June 2022Updated ' PCR home test instructions... (print version) ' and accompanying HTML. Replaced ' COVID-19 Priority PCR test instructions (easy read) ' . 30 May 2022Updated 119 phone line opening hours.
Source: Current Awareness Service for Health (CASH) - June 22, 2022 Category: Consumer Health News Source Type: news

Demographic and regional factors associated with reporting homicides of transgender people in the United States - Fouch é TW, Zakrison TL, Schneider JA, Kaufman EJ, Plackett TP, Velopulos C, Slidell MB, Voisin D, Hampton DA, Carmichael HE, Valdés DM, Parker C, Ross B, Chaudhary M, Cirone J.
INTRODUCTION: The American Medical Association recently declared homicides of transgender individuals an epidemic. However, transgender homicide victims are often classified as nontransgender. Our objective was to describe existing data and coding of trans...
Source: SafetyLit - June 22, 2022 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Society to Cells / Research News
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Source: Johns Hopkins University and Health Systems Archive - June 15, 2022 Category: Nursing Source Type: news

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