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This page shows you the most recent publications within this specialty of the MedWorm directory.

Analytical modeling and feasibility study of a multi-GPU cloud-based server (MGCS) framework for non-voxel-based dose calculations
ConclusionsThe results showed that a cloud-based computation engine was a feasible solution for enabling clinics to make use of fast dose calculations for advanced treatment planning and adaptive radiotherapy. The cloud-based system was able to exceed the performance of a local machine even for optimized calculations, and provided significant acceleration for computationally intensive tasks. Such a framework can provide access to advanced technology and computational methods to many clinics, providing an avenue for standardization across institutions without the requirements of purchasing, maintaining, and continually upda...
Source: International Journal of Computer Assisted Radiology and Surgery - August 25, 2016 Category: Intensive Care Source Type: research

Circadian Rhythm Associated with the Onset of Clinical Scenario 1 (CS1) Acute Decompensated Heart Failure (ADHF)
Circadian rhythm plays a role in various situations of cardiovascular physiology and pathology. The clinical scenario (CS), as management-oriented classification of acute decompensated heart failure (ADHF) was introduced to clinical practice. AS The association between circadian rhythm and the onset of ADHF remains obscure, this study aimed to address the association between the onset of ADHF in each CS and circadian rhythm. Methods and Results: A cohort of 145 patients with ADHF admitted to the cardiac intensive-care unit in Juntendo University Hospital since November 2014 to December 2015 was subjected to the study. (Sou...
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Masaru Hiki, Hiroshi Iwata, Kiyoshi Takasu, Shoichiro Yatsu, Azusa Murata, Takao Kato, Shoko Suda, Takatoshi Kasai, Tetsuro Miyazaki, Hiroyuki Daida Source Type: research

Worsening Renal Function Worsened in-Hospital Mortality in Acute Heart Failure Patients with Reduced but not with Preserved Left Ventricular Contraction
This study initially included 178 consecutive patients who were urgently hospitalized in the intensive care unit due to worsening of HF. After the exclusion of 20 hemodialysis patients and 15 patients without EF data, 144 patients were divided into 2 groups depending on EF with cut-off value of 40%. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Kentaro Jujo, Yusuke Tanigaito, Yuichiro Minami, Yasuhiro Kikuchi, Kensuke Shimazaki, Shintaro Haruki, Ryosuke Itani, Hiroyuki Arashi, Junichi Yamaguchi, Nobuhisa Hagiwara Source Type: research

Impact of Worsening Renal Function during Hospitalization on Long-Term Clinical Outcome in Patients with Acute Decompensated Heart Failure
Background: Despite advances in the management of heart failure, the prognosis of patients with acute decompensated heart failure (ADHF) remains poor. Worsening renal function (WRF) during hospitalization due to ADHF has been reported to relate with poor short-term clinical outcomes. However, few studies have examined the impact of WRF during hospitalization on long-term clinical outcomes. Methods: A cohort of 1684 consecutive patients admitted to the cardiac intensive-care unit from 2007 to 2011 was studied. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Masaru Hiki, Takatoshi Kasai, Hiroki Matsumoto, Azusa Murata, Takao Kato, Shoko Suda, Tetsuro Miyazaki, Atsutoshi Takagi, Hiroyuki Daida Source Type: research

Hypoalbuminemia on Admission Was Not Associated with Long-Term Mortality in Japanese Patients with Acute Decompensated Heart Failure
Background: Hypoalbuminemia has been emphasized in patients with heart failure (HF). However, it remains controversial whether hypoalbuminemia is associated with worse prognosis in acute decompensated HF (ADHF). In fact, conflicting results were reported from United States ADHF population. Thus, in the present study, prognostic importance of admission hypoalbuminemia in Japanese ADHF patients was investigated. Methods: A cohort of 1684 consecutive patients admitted to the cardiac intensive-care unit from 2007 to 2011 was studied. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Shoichiro Yatsu, Takatoshi Kasai, Hiroki Matsumoto, Azusa Murata, Takao Kato, Shoko Suda, Masaru Hiki, Atsutoshi Takagi, Hiroyuki Daida Source Type: research

Clinical Significance of the Measurement of Urinary Liver-Fatty Acid-Binding Protein (LFABP) Excretion in Acute Heart Failure Patients
Background: The clinical significance of urinary liver-fatty acid-binding protein (u-LFABP) in acute heart failure (AHF) patients was obscured yet. Methods and Results: Two hundred ninety-four AHF patients who admitted to the intensive care unit and measured u-LFABP on admission were analyzed. The median u-LFABP levels were 57.5 [14.5 to 183.5] ng/ml cre, and divided to two group according to the quartiles of u-LFABP (Q1 (Low-LFABP group) v.s. Q2, Q3 and Q4 (High-LFABP group)). We evaluate the diagnostic and prognostic value of u-LFABP in each chronic kidney disease (CKD) (n  = 166) or non-CKD patients (n = 129). (...
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Akihiro Shirakabe, Nobuaki Kobayashi, Hirotake Okazaki, Masato Matsushita, Junsuke Shibuya, Suguru Nishigoori, Noritake Hata, Kuniya Asai, Wataru Shimizu Source Type: research

Relationship between Admission C-Reactive Protein Level and Long-Term Mortality in Patients with Acute Decompensated Heart Failure
Background: Admission C-reactive protein (CRP) level is an important predictor of poor prognosis among several cardiovascular diseases such as acute coronary syndrome. In patients with acute decompensated heart failure (ADHF), admission CRP level is also related to the increased in-hospital mortality, but its relationship to the long-term mortality has not demonstrated yet. Methods: A cohort of 1684 consecutive patients admitted to the cardiac intensive-care unit from 2007 to 2011 was studied. Among them, patients with acute coronary syndrome and neoplasms were excluded, and then patients with ADHF were divided into 4 grou...
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Hiroki Matsumoto, Takatoshi Kasai, Shoichiro Yatsu, Azusa Murata, Takao Kato, Shoko Suda, Masaru Hiki, Atsutoshi Takagi, Katsumi Miyauchi, Hiroyuki Daida Source Type: research

A Case of Difficult in the Treatment of Heart Failure After Acute Myocardial Infarction of the Left Main Coronary Artery
A 70-year-old male had chest pain and in a shock status, was received an emergency catheterization with intra aortic balloon pumping. He had developed an acute myocardial infarction of the left main coronary artery, then percutaneous coronary intervention was done. Because infarct size were large, peak CPK was 9673  IU/L and and peak CK-MB was 690 ng/ml with high value. Congestive heart failure (CHF) was worsened after admission to intensive care unit, so mechanical ventilation was performed. After extubation, medication was adjusted and cardiac rehabilitation was done, but pulmonary congestion had remaine d. (Source: ...
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Yoji Tamaki, Yoshihiro Masaki, Taro Koya, Toshihiro Shimizu, Takayuki Hirabayashi Source Type: research

Adverse Infant Outcomes Associated with Discordant Gestational Age Estimates
ConclusionsInfants classified as preterm by ultrasound/best estimate, but term by LMP have consistently higher risks of adverse outcomes than those classified as preterm by LMP but term by ultrasound/best estimate. Compared with ultrasound/best estimate, use of LMP overestimates the proportion of births that are preterm. (Source: Paediatric and Perinatal Epidemiology)
Source: Paediatric and Perinatal Epidemiology - August 24, 2016 Category: Perinatology & Neonatology Authors: Nils ‐Halvdan Morken, Rolv Skjærven, Jennifer L. Richards, Michael R. Kramer, Sven Cnattingius, Stefan Johansson, Mika Gissler, Siobhan M. Dolan, Jennifer Zeitlin, Michael S. Kramer, Tags: Original Article Source Type: research

Measurement of functional and morphodynamic neutrophil phenotypes in systemic inflammation and sepsis
(Source: Critical Care)
Source: Critical Care - August 24, 2016 Category: Intensive Care Authors: Rens Zonneveld, G. Molema and Frans B. Pl ötz Source Type: research

End-inspiratory pause prolongation in acute respiratory distress syndrome patients: effects on gas exchange and mechanics
End-inspiratory pause (EIP) prolongation decreases dead space-to-tidal volume ratio (Vd/Vt) and PaCO2. We do not know the physiological benefits of this approach to improve respiratory system mechanics in acute r... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - August 24, 2016 Category: Intensive Care Authors: Hernan Aguirre-Bermeo, Indalecio Mor án, Maurizio Bottiroli, Stefano Italiano, Francisco José Parrilla, Eugenia Plazolles, Ferran Roche-Campo and Jordi Mancebo Source Type: research

Teamwork enables high level of early mobilization in critically ill patients
Early mobilization in critically ill patients has been shown to prevent bed-rest-associated morbidity. Reported reasons for not mobilizing patients, thereby excluding or delaying such intervention, are diverse... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - August 24, 2016 Category: Intensive Care Authors: Cheryl Elizabeth Hickmann, Diego Castanares-Zapatero, Emilie Bialais, Jonathan Dugernier, Antoine Tordeur, Lise Colmant, Xavier Wittebole, Giuseppe Tirone, Jean Roeseler and Pierre-Fran çois Laterre Source Type: research

How the Enhanced Neonatal Nurse Practitioner role has been integral to one tertiary unit's workforce plan and service delivery
This article will discuss both roles and examine how the Enhanced Neonatal Nurse Practitioner role has been developed to help address the medical workforce challenges and offer nursing career development within one trust in Greater Manchester. (Source: Journal of Neonatal Nursing)
Source: Journal of Neonatal Nursing - August 24, 2016 Category: Perinatology & Neonatology Source Type: research

Acoustic environment profile of the neonatal intensive care unit: High ambient  noise and limited language exposure
Publication date: August 2016 Source:Journal of Neonatal Nursing, Volume 22, Issue 4 Author(s): Vivian Y. Chow, Renée A. Shellhaas Infants in single-patient neonatal intensive care unit (NICU) rooms may experience developmental language delay because of reduced language exposure. We evaluated the acoustic profile of a level IV NICU using Language Environment Analysis (LENA) for 40 singleton infants. Mean and peak sound levels were consistently above 45 dB the recommended standard. NICU patients experienced substantial variability in language exposure (range: 10–2040 words per hour). Neither noise levels nor word count...
Source: Journal of Neonatal Nursing - August 24, 2016 Category: Perinatology & Neonatology Source Type: research

Improving pain management in  neonates exposed to intravenous insertions: A quality improvement initiative
Conclusion There is significant evidence that increased knowledge in neonatal pain management, the proper administration of sucrose including increased sucrose utilization will result in better pain management among neonates exposed to intravenous insertions. (Source: Journal of Neonatal Nursing)
Source: Journal of Neonatal Nursing - August 24, 2016 Category: Perinatology & Neonatology Source Type: research

Immunotherapy of Sepsis: Blind Alley or Call for Personalized Assessment?
AbstractSepsis is the most frequent cause of death in noncoronary intensive care units. In the past 10  years, progress has been made in the early identification of septic patients and their treatment. These improvements in support and therapy mean that mortality is gradually decreasing, however, the rate of death from sepsis remains unacceptably high. Immunotherapy is not currently part of the rout ine treatment of sepsis. Despite experimental successes, the administration of agents to block the effect of sepsis mediators failed to show evidence for improved outcome in a multitude of clinical trials. The following survey...
Source: Archivum Immunologiae et Therapiae Experimentalis - August 24, 2016 Category: Allergy & Immunology Source Type: research

The effects of massage therapy on physical growth and gastrointestinal function in premature infants: A pilot study
This study showed massage therapy has the potential effects on increasing physical growth and gastrointestinal function in premature infants. The massage in the NICU might be utilized as a part of developmental care, but more research needs to be done. NICU nurses need to be trained in massage therapy techniques to provide more effective clinical care for premature infants. (Source: Journal of Child Health Care)
Source: Journal of Child Health Care - August 24, 2016 Category: Pediatrics Authors: Choi, H., Kim, S.-J., Oh, J., Lee, M.-N., Kim, S., Kang, K.-A. Tags: Articles Source Type: research

Ventilator-associated pneumonia: A persistent healthcare problem in Indian Intensive Care Units!
Conclusions: VAP continues to be a major threat to patients who are admitted for mechanical ventilation into the critical care unit, emphasizing the urgent need for infection control measures. (Source: Lung India)
Source: Lung India - August 24, 2016 Category: Respiratory Medicine Authors: Ashu Sara Mathai Atul Phillips Rajesh Isaac Source Type: research

Cardiac troponin trends and severity in chronic obstructive pulmonary disease exacerbation: Are limits properly associated for Intensive Care Unit outcome ?
Fatma Yildirim, Antonio M EsquinasLung India 2016 33(5):583-584 (Source: Lung India)
Source: Lung India - August 24, 2016 Category: Respiratory Medicine Authors: Fatma Yildirim Antonio M Esquinas Source Type: research

Stress and distress in parents of neonates admitted to the neonatal intensive care unit for cardiac surgery
Parents of infants admitted to the Neonatal Intensive Care Unit (NICU) are at risk of psychological distress and NICU-related stress. However, parents of infants admitted to NICU for cardiac surgery are an under-researched population. (Source: Early Human Development)
Source: Early Human Development - August 24, 2016 Category: Perinatology & Neonatology Authors: J. Diffin, K. Spence, T. Naranian, N. Badawi, L. Johnston Source Type: research

Risk factors and clinical analysis of candidemia in very-low-birth-weight neonates
Conclusion Very-low-birth-weight infants are at a significantly high risk of developing candidemia. The local neonatal intensive care unit management teams should effectively focus on decreasing the overall use of carbapenems, improving catheter care, removing catheters early, and shortening hospitalizations to reduce the incidence of candidemia. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - August 24, 2016 Category: Infectious Diseases Source Type: research

Water faucets as a source of Pseudomonas aeruginosa infection and colonization in neonatal and adult intensive care unit patients
Publication date: Available online 24 August 2016 Source:American Journal of Infection Control Author(s): Regev Cohen, Frida Babushkin, Zvi Shimoni, Shoshana Cohen, Eti Litig, Maurice Shapiro, Amos Adler, Svetlana Paikin We investigated the occurrence of Pseudomonas aeruginosa in our neonatal and adult intensive care units. Using enterobacterial repetitive intergenic consensus polymerase chain reaction, we showed spatial and temporal associations with clonal identity between patients' and adjacent faucets' clones. Both units' taps were highly colonized with P aeruginosa and with other waterborne bacteria. In the neonatal ...
Source: American Journal of Infection Control - August 24, 2016 Category: Infectious Diseases Source Type: research

The Effect of Nursing Care Protocol on the Prevention of Central Venous Catheter-Related Infections in Neurosurgery Intensive Care Unit
This clinical study was planned to determine the effect of Nursing Care Protocol on the prevention of central venous catheter-related infections in neurosurgery intensive care unit. (Source: Applied Nursing Research : ANR)
Source: Applied Nursing Research : ANR - August 24, 2016 Category: Nursing Authors: Hatice Kaya, Y üksel Turan, Sade Akbal, Keziban Tosun, Esra Aksoy, Yusuf Tunalı, Gülsün Özdemir Aydın Source Type: research

Comparison of maternal and neonatal outcomes from full-dilatation cesarean deliveries using the Fetal Pillow or hand-push method
Conclusion The Fetal Pillow appears to be a safe and effective aid for the delivery of the fetal head during cesarean deliveries at full dilatation. (Source: International Journal of Gynecology and Obstetrics)
Source: International Journal of Gynecology and Obstetrics - August 24, 2016 Category: OBGYN Source Type: research

Risk factors associated with post-extubation stridor in the trauma intensive care unit
Conclusions Trauma ICU patients are reintubated for stridor at a higher rate than medical ICU patients. Age, gender, blunt mechanism, and duration of intubation are risk factors for this complication. (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - August 24, 2016 Category: Surgery Source Type: research

Outcome of Candida parapsilosis complex infections treated with caspofungin in children
Conclusions: Caspofungin is an attractive option due to its effects on biofilms in vivo, while the reflection of its affect onC.parapsilosiscomplex was limited in our study, but it should not be underestimated in children who strongly need the presence of central venous catheters. Moreover, in vivo susceptibility might not always guarantee good clinical response in clinical practice. The clinicians should weigh their priority for their patients and choose the optimal antifungal therapy forC.parapsilosiscomplex infections in children. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 23, 2016 Category: Hematology Source Type: research

Caudal analgesia and cardiothoracic surgery: a look at postoperative pain scores in a pediatric population
ConclusionAlthough regional anesthesia reduced intraoperative opioid usage, there was no difference in postoperative opioid usage or pain scores. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - August 23, 2016 Category: Anesthesiology Authors: Khoa N. Nguyen, Heather S. Byrd, Jonathan M. Tan Tags: Research Report Source Type: research

Regional Anesthesia is Associated With Decreased Postoperative Hypertension in Patients Undergoing Eversion Carotid Endarterectomy
Eversion carotid endarterectomy (eCEA) has been effective in reducing stroke risk in patients with carotid artery stenosis. Recent literature shows that patients who undergo eCEA are at risk for development of postoperative hypertension requiring intravenous (IV) antihypertensive medication. The purpose of this study was to assess whether the type of anesthesia (regional or general) has an impact on the incidence of postoperative hypertension requiring IV antihypertensive medication in the surgical intensive care unit (SICU) in patients undergoing eCEA. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - August 23, 2016 Category: Surgery Authors: Felecia Jinwala, Justin Oh, Viktor Dombrovskiy, Khanjan Nagarsheth, Saum Rahimi Tags: Abstract from the 2016 Eastern Vascular Society Annual Meeting Source Type: research

Noninvasive ventilation with helmet versus control strategy in patients with acute respiratory failure: a systematic review and meta-analysis of controlled studies
Noninvasive ventilation (NIV) has proved to be a useful technique for breathing support. However, complications, discomfort, and failure of NIV were commonly caused by the mask. Therefore, the helmet was devel... (Source: Critical Care)
Source: Critical Care - August 23, 2016 Category: Intensive Care Authors: Qi Liu, Yonghua Gao, Rongchang Chen and Zhe Cheng Source Type: research

An Elevation of Serum Ferritin Level Might Increase Clinical Risk for the Persistence of Patent Ductus Arteriosus, Sepsis and Bronchopulmonary Dysplasia in Erythropoietin-Treated Very-Low-Birth-Weight Infants
Background: The substantial risk of iron overload is not routinely monitored in most of the neonatal intensive care units (NICUs) in Japan; however, blood transfusion is an essential strategy for successfully treating preterm low-birth-weight infants.Objective: The aim of this study was to investigate the iron status and clinical features of infants with a birth weight of (Source: Neonatology)
Source: Neonatology - August 23, 2016 Category: Perinatology & Neonatology Source Type: research

Risk factors for candidaemia in critically ill patients in intensive care units as compared to internal medicine wards
. (Source: Infectious Diseases)
Source: Infectious Diseases - August 23, 2016 Category: Infectious Diseases Authors: Carlo Tascini Emanuela Sozio Nicola Salini Francesco Sbrana Andrea Ripoli Bruno Viaggi Paolo Malacarne Source Type: research

Nifedipine maintenance tocolysis and perinatal outcome: an individual participant data meta ‐analysis
ConclusionMaintenance tocolysis is not associated with improved perinatal outcome and is therefore not recommended for routine practice. Tweetable abstractNifedipine maintenance tocolysis is not associated with improved perinatal outcome or pregnancy prolongation. (Source: BJOG: An International Journal of Obstetrics and Gynaecology)
Source: BJOG: An International Journal of Obstetrics and Gynaecology - August 23, 2016 Category: OBGYN Authors: EOG Vliet, GH Dijkema, E Schuit, KY Heida, C Roos, JAM Post, EC Parry, L McCowan, DJ Lyell, YY El ‐Sayed, DB Carr, AL Clark, ZA Mahdy, M Uma, NC Sayin, GF Varol, BW Mol, MA Oudijk Tags: Systematic review Source Type: research

Relevance of serum sclerostin concentrations in critically ill patients
Sclerostin is a negative regulator of bone metabolism and associated with chronic morbidities. We investigated circulating sclerostin in critically ill patients. (Source: Journal of Critical Care)
Source: Journal of Critical Care - August 23, 2016 Category: Intensive Care Authors: Alexander Koch, Ralf Weiskirchen, Sebastian Ludwig, Lukas Buendgens, Jan Bruensing, Eray Yagmur, Christer Baeck, Ulf Herbers, Christian Trautwein, Frank Tacke Source Type: research

Cardiac Manifestations and Associations with Gene Mutations in Patients Diagnosed with RASopathies
AbstractRASopathies are a group of syndromes caused by germline mutations of the RAS/MAPK pathway. They include Noonan syndrome, cardio-facio-cutaneous syndrome, Costello syndrome, and Noonan syndrome with multiple lentigines, which share many characteristic features including cardiac abnormalities. Here, we retrospectively reviewed the clinical manifestations and evaluated the genotype –phenotype associations with special focus on cardiac lesions of the patients with RASopathies. Cardiac symptoms were the most common initial presentation (27 %), except for admission to neonatal intensive care. Although there was a sign...
Source: Pediatric Cardiology - August 23, 2016 Category: Cardiology Source Type: research

A Practical Approach to Ketogenic Diet in the Pediatric Intensive Care Unit for Super-Refractory Status Epilepticus
ConclusionsWe demonstrated the feasibility of a practical approach to initiation of KD for children with SRSE. These children were successfully weaned off continuous anesthetic infusions. Larger studies are needed to determine effectiveness, safety, and tolerability of KD in the management of SRSE as well as ease of implementation. (Source: Neurocritical Care)
Source: Neurocritical Care - August 23, 2016 Category: Neurology Source Type: research

A newly designed observation and response chart's effect upon adverse inpatient outcomes and rapid response team activity
ConclusionObservation and response charts increased RRT and ICU workload without improving cardiac arrest rate or mortality. Future chart evaluation should identify features beneficial to patient outcomes and refine those that consume critical care resources that are not associated with improved patient outcomes. (Source: Internal Medicine Journal)
Source: Internal Medicine Journal - August 23, 2016 Category: Internal Medicine Authors: A. O'Connell, A. Flabouris, S. W. Kim, C. Horwood, P. Hakendorf, C. H. Thompson Tags: Original Article Source Type: research

Selecting relevant 3D image features of margin sharpness and texture for lung nodule retrieval
ConclusionFeature space dimensionality reduction of 83  % obtained higher retrieval performance and presented to be a computationaly low cost method of retrieving similar nodules for the diagnosis of lung cancer. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - August 23, 2016 Category: Intensive Care Source Type: research

Determinants of Carboxyhemoglobin Levels and Relationship with Sepsis in a Retrospective Cohort of Preterm Neonates
by Andrew J. McArdle, James Webbe, Kathleen Sim, Graham Parrish, Clive Hoggart, Yifei Wang, J. Simon Kroll, Sunit Godambe, Aubrey J. Cunnington Carboxyhemoglobin levels in blood reflect endogenous carbon monoxide production and are often measured during routine blood gas analysis. Endogenous carbon monoxide production has been reported to be increased during sepsis, but carboxyhemoglobin levels have not been thoroughly evaluated as a biom arker of sepsis. We sought to determine whether carboxyhemoglobin levels were elevated during sepsis in a high risk population of premature neonates. We conducted a retrospective cohort ...
Source: PLoS One - August 23, 2016 Category: Biomedical Science Authors: Andrew J. McArdle Source Type: research

Obesity and Airway Dysanapsis in Children With and Without Asthma.
CONCLUSIONS: Obesity is associated with airway dysanapsis in children. Dysanapsis is associated with increased morbidity among obese children with asthma, and may partly explain their reduced response to inhaled corticosteroids. PMID: 27552676 [PubMed - as supplied by publisher] (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - August 23, 2016 Category: Intensive Care Authors: Forno E, Weiner DJ, Mullen J, Sawicki G, Kurland G, Han YY, Cloutier MM, Canino G, Weiss ST, Litonjua AA, Celedón JC Tags: Am J Respir Crit Care Med Source Type: research

Anti-N-methyl-D-aspartate Receptor Encephalitis in Adult Patients Requiring Intensive Care.
CONCLUSIONS: The prognosis of adult patients with anti-NMDAR encephalitis requiring intensive care is good, especially when immunotherapy is initiated early, advocating for prompt diagnosis and early aggressive treatment. PMID: 27552490 [PubMed - as supplied by publisher] (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - August 23, 2016 Category: Intensive Care Authors: de Montmollin É, Demeret S, Brulé N, Conrad M, Dailler F, Lerolle N, Navellou JC, Schwebel C, Alves M, Cour M, Engrand N, Tonnelier JM, Maury E, Ruckly S, Picard G, Rogemond V, Magalhaes É, Sharshar T, Timsit JF, Honnorat J, Sonneville R, ENCEPHALITICA Tags: Am J Respir Crit Care Med Source Type: research

An Elevation of Serum Ferritin Level Might Increase Clinical Risk for the Persistence of Patent Ductus Arteriosus, Sepsis and Bronchopulmonary Dysplasia in Erythropoietin-Treated Very-Low-Birth-Weight Infants.
CONCLUSIONS: Hyperferritinemia might be associated with oxygen radical diseases and susceptibility to infection. PMID: 27547966 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - August 23, 2016 Category: Perinatology & Neonatology Authors: Ochiai M, Kurata H, Inoue H, Tanaka K, Matsushita Y, Fujiyoshi J, Wakata Y, Kato K, Taguchi T, Takada H Tags: Neonatology Source Type: research

Hemotransfusion and mechanical ventilation time are associated with intra-hospital mortality in patients with traumatic brain injury admitted to intensive care unit
Conclusion After multivariate analysis, the factors associated with intra-hospital mortality in TBI patients admitted to the intensive care unit were the administration of hemocomponents and mechanical ventilation time.RESUMO Objetivo Identificar os fatores associados à mortalidade intra-hospitalar em pacientes com TCE internados em unidade de terapia intensiva (UTI). Métodos A amostra incluiu pacientes com TCE internados na UTI em um período de um ano. Foi definido como variáveis as características epidemiológicas, os fatores associados ao trauma e variá veis decorrentes dos cuidados clínicos na UTI. Resultados A ...
Source: Arquivos de Neuro-Psiquiatria - August 22, 2016 Category: Neurology Source Type: research

Outcome of Candida parapsilosis complex infections treated with caspofungin in children
Conclusions: Caspofungin is an attractive option due to its effects on biofilms in vivo, while the reflection of its affect onC.parapsilosiscomplex was limited in our study, but it should not be underestimated in children who strongly need the presence of central venous catheters. Moreover, in vivo susceptibility might not always guarantee good clinical response in clinical practice. The clinicians should weigh their priority for their patients and choose the optimal antifungal therapy forC.parapsilosiscomplex infections in children. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 22, 2016 Category: Hematology Source Type: research

Impact of a pharmacist-driven protocol to decrease proton pump inhibitor use in non-intensive care hospitalized adults.
CONCLUSION: The pharmacist-driven protocol described in this study decreased PPI use in non-ICU hospitalized adults. PMID: 27543598 [PubMed - as supplied by publisher] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - August 22, 2016 Category: Drugs & Pharmacology Authors: Michal J, Henry T, Street C Tags: Am J Health Syst Pharm Source Type: research

Airway driving pressure and lung stress in ARDS patients
Lung-protective ventilation strategy suggests the use of low tidal volume, depending on ideal body weight, and adequate levels of PEEP. However, reducing tidal volume according to ideal body weight does not al... (Source: Critical Care)
Source: Critical Care - August 22, 2016 Category: Intensive Care Authors: Davide Chiumello, Eleonora Carlesso, Matteo Brioni and Massimo Cressoni Source Type: research

Sensors, Vol. 16, Pages 1337: Factors Influencing Continuous Breath Signal in Intubated and Mechanically-Ventilated Intensive Care Unit Patients Measured by an Electronic Nose
Conclusion: Variations in humidity, ventilator disconnections, nebulization of medication and changes of ventilator settings indeed influenced exhaled breath signals measured in ventil ated patients by continuous eNose analysis. We discussed several approaches to reduce the effects of these noise inducing variables. (Source: Sensors)
Source: Sensors - August 22, 2016 Category: Biotechnology Authors: Jan Leopold Ameen Abu-Hanna Camilla Colombo Peter Sterk Marcus Schultz Lieuwe Bos Tags: Article Source Type: research

Intraoperative lung ultrasound: A clinicodynamic perspective
Amit Kumar Mittal, Namrata GuptaJournal of Anaesthesiology Clinical Pharmacology 2016 32(3):288-297In the era of evidence-based medicine, ultrasonography has emerged as an important and indispensable tool in clinical practice in various specialties including critical care. Lung ultrasound (LUS) has a wide potential in various surgical and clinical situations for timely and easy detection of an impending crisis such as pulmonary edema, endobronchial tube migration, pneumothorax, atelectasis, pleural effusion, and various other causes of desaturation before it clinically ensues to critical level. Although ultrasonography is ...
Source: Journal of Anaesthesiology Clinical Pharmacology - August 22, 2016 Category: Anesthesiology Authors: Amit Kumar Mittal Namrata Gupta Source Type: research