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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 10.

Respiratory and autonomic dysfunction in congenital central hypoventilation syndrome
The developmental lineage of the PHOX2B-expressing neurons in the retrotrapezoid nucleus (RTN) has been extensively studied. These cells are thought to function as central respiratory chemoreceptors, i.e., the mechanism by which brain Pco2 regulates breathing. The molecular and cellular basis of central respiratory chemoreception is based on the detection of CO2 via intrinsic proton receptors (TASK-2, GPR4) as well as synaptic input from peripheral chemoreceptors and other brain regions. Murine models of congenital central hypoventilation syndrome designed with PHOX2B mutations have suggested RTN neuron agenesis. In this r...
Source: Journal of Neurophysiology - August 16, 2016 Category: Neurology Authors: Moreira, T. S., Takakura, A. C., Czeisler, C., Otero, J. J. Tags: Call For Papers Source Type: research

Hypoalbuminemia Is a Better Predictor than Obesity of Complications After Total Knee Arthroplasty: a Propensity Score-Adjusted Observational Analysis
ConclusionsHypoalbuminemia is a more consistent independent predictor of complications after TKA than obesity. Strategies for medical optimization of these conditions should be investigated. (Source: HSS Journal)
Source: HSS Journal - August 16, 2016 Category: Orthopaedics Source Type: research

Gas exchange responses during 6 ‐min walk test in patients with pulmonary arterial hypertension
ConclusionWhilst 6MWT and gas exchange did not differentiate between PAH groups, individuals with more severe disease and on more advanced pharmacotherapy had poorer gas exchange during exercise. (Source: Respirology)
Source: Respirology - August 16, 2016 Category: Respiratory Medicine Authors: Norman R. Morris, Helen Seale, Julie Harris, Kathleen Hall, Aaron C. W. Lin, Fiona Kermeen Tags: Original Article Source Type: research

The Association Between Maternal Employment and Prevalence of Asthma in Children
Pediatric Allergy, Immunology, and Pulmonology , Vol. 0, No. 0. (Source: Pediatric, Allergy, Immunology, and Pulmonology)
Source: Pediatric, Allergy, Immunology, and Pulmonology - August 16, 2016 Category: Respiratory Medicine Authors: Naoya Hashimoto Hideki Hashimoto Source Type: research

Proximity to a Major Road and Plasma Cytokines in School-Aged Children
Pediatric Allergy, Immunology, and Pulmonology , Vol. 0, No. 0. (Source: Pediatric, Allergy, Immunology, and Pulmonology)
Source: Pediatric, Allergy, Immunology, and Pulmonology - August 16, 2016 Category: Respiratory Medicine Authors: Franziska Rosser Erick Forno John Brehm Yueh-Ying Han Nadia Boutaoui Angel Col ón-Semidey Mar ía Alvarez Edna Acosta-P érez Kristen S. Kurland John F. Alcorn Glorisa Canino Juan C. Celed ón Source Type: research

Intermittent hypoxia promotes recovery of respiratory motor function in spinal cord-injured mice depleted of serotonin in the central nervous system
We examined the effect of repeated daily exposure to intermittent hypoxia (IH) on the recovery of respiratory and limb motor function in mice genetically depleted of central nervous system serotonin. Electroencephalography, diaphragm activity, ventilation, core body temperature, and limb mobility were measured in spontaneously breathing wild-type (Tph2+/+) and tryptophan hydroxylase 2 knockout (Tph2–/–) mice. Following a C2 hemisection, the mice were exposed daily to IH (i.e., twelve 4-min episodes of 10% oxygen interspersed with 4-min normoxic periods followed by a 90-min end-recovery period) or normoxia (i.e....
Source: Journal of Applied Physiology - August 16, 2016 Category: Physiology Authors: Komnenov, D., Solarewicz, J. Z., Afzal, F., Nantwi, K. D., Kuhn, D. M., Mateika, J. H. Tags: ARTICLES Source Type: research

Mechanical Stress and Single Nucleotide Variants Regulate Alternative Splicing of the MYLK Gene.
In this study, we utilized minigene constructs and RT-PCR to interrogate biophysical factors (mechanical stress) and genetic variants (MYLK SNPs) that are potentially involved in regulating MYLK alternative splicing and nmMLCK2 generation. Human lung EC exposed to pathologic mechanical stress (18% cyclic stretch) produced increased nmMLCK2 expression relative to levels of nmMLCK1 with alternative splicing significantly influenced by MYLK SNPs rs77323602 and rs147245669. In silico analyses predicted these variants to alter exon 11 donor and acceptor sites for alternative splicing, computational predictions that were confirm...
Source: American Journal of Respiratory Cell and Molecular Biology - August 16, 2016 Category: Molecular Biology Authors: Mascarenhas JB, Tchourbanov AY, Fan H, Danilov SM, Wang T, Garcia JG Tags: Am J Respir Cell Mol Biol Source Type: research

Application of ICD-PM to preterm-related neonatal deaths in the UK and South Africa.
CONCLUSIONS: ICD-PM can be used to appraise the maternal and newborn conditions contributing to preterm deaths, and can inform practice. TWEETABLE ABSTRACT: ICD-PM can be used to appraise maternal and newborn contributors to preterm deaths to improve quality of care. PMID: 27527390 [PubMed - as supplied by publisher] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - August 16, 2016 Category: OBGYN Authors: Allanson ER, Vogel JP, Tunçalp Ӧ, Gardosi J, Pattinson RC, Francis A, Erwich J, Flenady VJ, Frøen JF, Neilson J, Quach A, Chou D, Mathai M, Say L, Gülmezoglu AM Tags: BJOG Source Type: research

Self-gated 4D multiphase, steady-state imaging with contrast enhancement (MUSIC) using rotating cartesian K-space (ROCK): Validation in children with congenital heart disease.
CONCLUSION: ROCK-MUSIC provided images of equal or superior image quality compared to original MUSIC, and this was achievable with 40% savings in scan time and without the need for physiologic signal. Magn Reson Med, 2016. © 2016 International Society for Magnetic Resonance in Medicine. PMID: 27529745 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - August 16, 2016 Category: Radiology Authors: Han F, Zhou Z, Han E, Gao Y, Nguyen KL, Finn JP, Hu P Tags: Magn Reson Med Source Type: research

Thrombolysis for Massive Pulmonary Embolism in a Patient with Hemorrhagic Shock.
PMID: 27529567 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 16, 2016 Category: Respiratory Medicine Authors: Papanikolaou J, Spathoulas K, Makris D, Zakynthinos E Tags: Am J Respir Crit Care Med Source Type: research

Assessment of Upper-Airway Configuration in Obstructive Sleep Apnea Syndrome With Computed Tomography Imaging During M üller Maneuver.
CONCLUSIONS: Subjects with severe OSAS have more significant abnormalities of the upper airway. Obesity, mCSA of nasopharynx, upper-airway length, and MPH may contribute to the severity of OSAS. Obesity and sex should be taken into account when evaluating the abnormalities of upper-airway anatomy in snorers and patients with OSAS. PMID: 27530419 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - August 16, 2016 Category: Respiratory Medicine Authors: Huang JF, Chen GP, Wang BY, Xie HS, Zhao JM, Wu LH, Chen LD, Lin QC Tags: Respir Care Source Type: research

Continuous High-Frequency Oscillation Therapy in Invasively Ventilated Pediatric Subjects in the Critical Care Setting.
CONCLUSIONS: CHFO is feasible and seems safe in our cohort of mechanically ventilated pediatric subjects. The rate of pneumothorax was consistent with that seen in similar pediatric ICU populations. These preliminary results suggest that CHFO may be beneficial by improving lung compliance in pediatric subjects with secretion-induced atelectasis. Prospective clinical studies are needed to further evaluate the clinical efficacy and safety of CHFO in children receiving invasive mechanical ventilation. PMID: 27530418 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - August 16, 2016 Category: Respiratory Medicine Authors: Morgan S, Hornik CP, Patel N, Williford WL, Turner DA, Cheifetz IM Tags: Respir Care Source Type: research

Physiological Responses to Repeated Stress in Individuals with High and Low Trait Resilience.
This study examined individual differences in trait resilience in physiological recovery from, and physiological habituation to, repeated stress (i.e. public speaking). Eighty-two college students were categorized as either high (n=40) or low (n=42) on trait resilience, based on the scores of the Connor-Davidson Resilience Scale (CD-RISC). Subjective and physiological data were collected from participants across seven laboratory stages: baseline, stress anticipation 1, stress 1, post-stress 1, stress anticipation 2, stress 2, and post-stress 2. Results indicated that high-trait-resilient participants exhibited more complet...
Source: Biological Psychology - August 16, 2016 Category: Psychiatry & Psychology Authors: Lü W, Wang Z, You X Tags: Biol Psychol Source Type: research

Pleural Effusion: A Rare Manifestation of Sarcoidosis.
PMID: 27542684 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - August 16, 2016 Category: Respiratory Medicine Authors: Fontecha Ortega M, Rodríguez Álvarez SJ, García Satué JL Tags: Arch Bronconeumol Source Type: research

Reverse-transcription loop-mediated isothermal amplification (RT-LAMP) assay for the visual detection of European and North American porcine reproductive and respiratory syndrome viruses.
Abstract A reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for visual detection of European (EU) and North American (NA) porcine reproductive and respiratory syndrome viruses (PRRSVs) was established and evaluated with reference PRRSV strains and clinical samples. The assay was performed in two reaction tubes containing each set of primers specific for EU or NA-PRRSV at 58°C for 40min, and the results could be visually detected by the naked eye, using hydroxynaphthol blue dye. The detection limit of the assay was 1 or 0.1 TCID50/0.1mL for EU or NA PRRSV, respectively, which was compar...
Source: Journal of Virological Methods - August 16, 2016 Category: Virology Authors: Park JY, Park S, Park YR, Kang DY, Kim EM, Jeon HS, Kim JJ, Kim WI, Lee KT, Kim SH, Lee KK, Park CK Tags: J Virol Methods Source Type: research

Microglia mediate diesel exhaust particle-induced cerebellar neuronal toxicity through neuroinflammatory mechanisms.
Abstract In addition to the well-established effects of air pollution on the cardiovascular and respiratory systems, emerging evidence has implicated it in inducing negative effects on the central nervous system. Diesel exhaust particulate matter (DEP), a major component of air pollution, is a complex mixture of numerous toxicants. Limited studies have shown that DEP-induced dopaminergic neuron dysfunction is mediated by microglia, the resident immune cells of the brain. Here we show that mouse microglia similarly mediate primary cerebellar granule neuron (CGN) death in vitro. While DEP (0, 25, 50, 100μg/2cm(2)) ...
Source: Neurotoxicology - August 16, 2016 Category: Neurology Authors: Roqué PJ, Dao K, Costa LG Tags: Neurotoxicology Source Type: research

Application of ICD ‐PM to preterm‐related neonatal deaths in South Africa and United Kingdom
ConclusionsICD‐PM can be used to appraise the maternal and newborn conditions contributing to preterm deaths, and can inform practice. Tweetable abstractICD‐PM can be used to appraise maternal and newborn contributors to preterm deaths to improve quality of care. (Source: BJOG: An International Journal of Obstetrics and Gynaecology)
Source: BJOG: An International Journal of Obstetrics and Gynaecology - August 16, 2016 Category: OBGYN Authors: ER Allanson, JP Vogel, Ӧ Tunçalp, J Gardosi, RC Pattinson, A Francis, JJHM Erwich, VJ Flenady, JF Frøen, J Neilson, A Quach, D Chou, M Mathai, L Say, AM Gülmezoglu Tags: Original Article Source Type: research

Evolution and Transmission of Respiratory Syncytial Group A (RSV-A) Viruses in Guangdong, China 2008 –2015
Lirong Zou, Lina Yi, Jie Wu, Yingchao Song, Guofeng Huang, Xin Zhang, Lijun Liang, Hanzhong Ni, Oliver G. Pybus, Changwen Ke, Jing Lu (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - August 15, 2016 Category: Microbiology Source Type: research

Calm Before the Storm: An Uncomplicated Epicardial Lead Extraction Resulting in DIC and Patient Demise
A previously stable 77-year-old man with significant cardiac history underwent an uneventful extraction of a Citrobacter-infected and eroded pacemaker lead. His postoperative course was acutely complicated by respiratory failure and quickly progressed into disseminated intravascular coagulation, acute renal failure, shock liver, and ventricular tachycardic arrest. I believe that this is the first case report of such a drastic turn of events after a routine pacemaker lead extraction. (Source: A&A Case Reports)
Source: A&A Case Reports - August 15, 2016 Category: Anesthesiology Tags: Case Reports: Case Report Source Type: research

Critical care ultrasonography in acute respiratory failure
Acute respiratory failure (ARF) is a leading indication for performing critical care ultrasonography (CCUS) which, in these patients, combines critical care echocardiography (CCE) and chest ultrasonography. CC... (Source: Critical Care)
Source: Critical Care - August 15, 2016 Category: Intensive Care Authors: Philippe Vignon, Xavier Repess é, Antoine Vieillard-Baron and Eric Maury Source Type: research

Greater levels of cardiorespiratory and muscular fitness are associated with low stress and high mental resources in normal but not overweight men
The aim of the present study was to investigate how cardio respiratory (CRF) and muscular fitness (MF) together with leisure-time physical activity (LTPA) influence stress symptoms and mental resources among n... (Source: BMC Public Health)
Source: BMC Public Health - August 15, 2016 Category: Consumer Health News Authors: O. Kettunen, H. Kyr öläinen, M. Santtila, T. Vuorimaa and T. J. Vasankari Source Type: research

Coexistence of pulmonary lymphangioleiomyomatosis and pulmonary angiomyolipoma
Lymphangioleiomyomatosis (LAM) and angiomyolipoma are two different, but related rare diseases. To the best of our knowledge, pulmonary LAM and pulmonary angiomyolipoma have not previously been observed in the... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - August 15, 2016 Category: Respiratory Medicine Authors: Xuefeng Sun, Ruie Feng, Ye Zhang, Juhong Shi and Kai-Feng Xu Source Type: research

Clinically integrated multi-organ point-of-care ultrasound for undifferentiated respiratory difficulty, chest pain, or shock: a critical analytic review
This article will review the role and utility of symptom-based and sign-oriented MOPOCUS in patients with undifferentiated respiratory difficulty, chest pain, or shock and how it can be performed in a timely, effective, and efficient manner. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - August 15, 2016 Category: Intensive Care Source Type: research

Cloning and expression analysis of innate immune genes from red sea bream to assess different susceptibility to megalocytivirus infection
Abstract As suggested by the Office International des Epizooties (OIE), fishes belonging to the genus Oplegnathus are more sensitive to megalocytivirus infection than other fish species including red sea bream (Pagrus major). To assess the roles of the innate immune response to these different susceptibilities, we cloned the genes encoding inflammatory factors including IL‐8 and COX‐2, and the antiviral factor like Mx from red sea bream for the first time and performed phylogenetic and structural analysis. Analysed expression levels of IL‐1β, IL‐8 and COX‐2 and the antiviral factor like Mx genes performed with i...
Source: Journal of Fish Diseases - August 15, 2016 Category: Zoology Authors: J W Jin, Y C Kim, S Hong, M S Kim, J B Jeong, H D Jeong Tags: Original Article Source Type: research

Sheffield Hallam Staff Wellness service: Four-year follow-up of the impact on health indicators
Conclusions: The service demonstrates that a university-based wellness service using a combination of motivational interviewing and health screening to elicit behaviour change (and subsequent improvements in health-related outcomes) was successful in improving the health of employees with an ‘at risk’ profile. (Source: Perspectives in Public Health)
Source: Perspectives in Public Health - August 15, 2016 Category: Health Management Authors: Flint, S. W., Scaife, R., Kesterton, S., Humphreys, L., Copeland, R., Crank, H., Breckon, J., Maynard, I., Carter, A. Tags: Peer Review Source Type: research

Protein tyrosine phosphatase 1B negatively regulates S100A9-mediated lung damage during respiratory syncytial virus exacerbations
mp; P Geraghty (Source: Mucosal Immunology)
Source: Mucosal Immunology - August 15, 2016 Category: Allergy & Immunology Authors: R F Foronjy P O Ochieng M A Salathe A J Dabo E Eden N Baumlin N Cummins S Barik M Campos E B Thorp P Geraghty Source Type: research

Performance of the clinical index of stable febrile neutropenia (CISNE) in different types of infections and tumors
ConclusionDespite FN ’s clinical and microbiological heterogeneity, the CISNE score was seen to be consistent and robust in spite of these variations. Hence, it appears to be a safe tool in seemingly stable FN. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - August 15, 2016 Category: Cancer & Oncology Source Type: research

Author response to: Effects of heated humidifier during CPAP titration in the cool sleeping environment
(Source: Sleep and Breathing)
Source: Sleep and Breathing - August 15, 2016 Category: Respiratory Medicine Source Type: research

Effects of heated humidifier during CPAP titration in the cool sleeping environment
(Source: Sleep and Breathing)
Source: Sleep and Breathing - August 15, 2016 Category: Respiratory Medicine Source Type: research

Step-down treatment from medium-dosage of budesonide/formoterol in controlled asthma
The stepping down of asthma treatment can be considered when asthma symptoms have been well controlled with inhaled corticosteroids (ICSs)/long-acting β2 adrenergic agonists (LABAs). However, few data are available comparing the efficacy between two step-down strategies, to reduce ICS/LABA dose or to withdraw LABA continuing ICS, in well-controlled asthmatics. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 15, 2016 Category: Respiratory Medicine Authors: Kazutaka Mori, Tomoyuki Fujisawa, Naoki Inui, Dai Hashimoto, Noriyuki Enomoto, Yutaro Nakamura, Shigeki Kuroishi, Koshi Yokomura, Mikio Toyoshima, Shiro Imokawa, Takashi Yamada, Toshihiro Shirai, Masafumi Masuda, Hiroshi Hayakawa, Kingo Chida, Takafumi Su Source Type: research

Cancer risk among lung transplant recipients with cystic fibrosis
We describe cancer incidence among CF and non-CF lung recipients. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - August 15, 2016 Category: Respiratory Medicine Authors: Aliza K. Fink, Elizabeth L. Yanik, Bruce C. Marshall, Michael Wilschanski, Charles F. Lynch, April A. Austin, Glenn Copeland, Mahboobeh Safaeian, Eric A. Engels Tags: Original Article Source Type: research

Music interventions for improving psychological and physical outcomes in cancer patients.
CONCLUSIONS: This systematic review indicates that music interventions may have beneficial effects on anxiety, pain, fatigue and QoL in people with cancer. Furthermore, music may have a small effect on heart rate, respiratory rate and blood pressure. Most trials were at high risk of bias and, therefore, these results need to be interpreted with caution. PMID: 27524661 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 15, 2016 Category: Journals (General) Authors: Bradt J, Dileo C, Magill L, Teague A Tags: Cochrane Database Syst Rev Source Type: research

Lung Transplantation in Children.
Authors: PMID: 27525467 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 15, 2016 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research

Reply: Analytical Performance Requirements for Biomarker-based Studies Evaluating Continuous Positive Airway Pressure Effects in Obstructive Sleep Apnea.
PMID: 27525466 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 15, 2016 Category: Respiratory Medicine Authors: Martínez-Cerón E, Buño A, Garcia-Rio F Tags: Am J Respir Crit Care Med Source Type: research

Reply: It Is Too Early to Say No Place for High-Frequency Oscillatory Ventilation in Children with Respiratory Failure.
PMID: 27525465 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 15, 2016 Category: Respiratory Medicine Authors: Bateman ST, Borasino S, Asaro LA, Cheifetz IM, Diane S, Wypij D, Curley MA Tags: Am J Respir Crit Care Med Source Type: research

Analytical Performance Requirements for Biomarker-based Studies Evaluating Continuous Positive Airway Pressure Effects in Obstructive Sleep Apnea.
PMID: 27525464 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 15, 2016 Category: Respiratory Medicine Authors: Monneret D Tags: Am J Respir Crit Care Med Source Type: research

It Is Too Early to Say No Place for High-Frequency Oscillatory Ventilation in Children with Respiratory Failure.
PMID: 27525463 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 15, 2016 Category: Respiratory Medicine Authors: Samransamruajkit R Tags: Am J Respir Crit Care Med Source Type: research

Survival after Endobronchial Valve Placement for Emphysema: A 10-Year Follow-up Study.
PMID: 27525462 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 15, 2016 Category: Respiratory Medicine Authors: Garner J, Kemp SV, Toma TP, Hansell DM, Polkey MI, Shah PL, Hopkinson NS Tags: Am J Respir Crit Care Med Source Type: research

Effect of One Week of 8-Hour Nightly Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea on Glycemic Control in Type 2 Diabetes: A Proof-of-Concept Study.
PMID: 27525461 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 15, 2016 Category: Respiratory Medicine Authors: Mokhlesi B, Grimaldi D, Beccuti G, Abraham V, Whitmore H, Delebecque F, Van Cauter E Tags: Am J Respir Crit Care Med Source Type: research