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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 15.

Trends in tuberculosis case notification and treatment outcomes after interventions in 10 zones of Ethiopia
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Dememew, Z. G. Habte, D. Melese, M. Hamusse, S. D. Nigussie, G. Hiruy, N. Girma, B. Kassie, Y. Haile, Y. K. Jerene, D. Suarez, P. Tags: ORIGINAL ARTICLES Source Type: research

Community knowledge, attitudes and practices in relation to tuberculosis in Cameroon
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Kwedi Nolna, S. Kammogne, I. D. Ndzinga, R. Afanda, B. Nton è, R. Boum, Y. Nolna, D. Tags: ORIGINAL ARTICLES Source Type: research

Multidrug-resistant tuberculosis patients lost to follow-up: self-reported readiness to restart treatment
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Mangan, J. M. Tupasi, T. E. Garfin, A. M. C. G. Lofranco, V. Orillaza-Chi, R. Basilio, R. Naval, L. C. Balane, G. I. Joson, E. S. Burt, D. Lew, W-J. Mantala, M. Pancho, S. Sarol, J. N. Golubkov, A. Kurbatova, E. V. Tags: ORIGINAL ARTICLES Source Type: research

Higher cost of implementing Xpert ® MTB/RIF in Ugandan peripheral settings: implications for cost-effectiveness
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Hsiang, E. Little, K. M. Haguma, P. Hanrahan, C. F. Katamba, A. Cattamanchi, A. Davis, J. L. Vassall, A. Dowdy, D. Tags: ORIGINAL ARTICLES Source Type: research

Modelling the time to detection of urban tuberculosis in two big cities in Portugal: a spatial survival analysis
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Nunes, C. Taylor, B. M. Tags: ORIGINAL ARTICLES Source Type: research

Computer-aided detection of pulmonary tuberculosis on digital chest radiographs: a systematic review
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Pande, T. Cohen, C. Pai, M. Ahmad Khan, F. Tags: ORIGINAL ARTICLES Source Type: research

SLCO1B1 gene polymorphisms do not influence plasma rifampicin concentrations in a South Indian population
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Ramesh, K. Hemanth Kumar, A. K. Kannan, T. Vijayalakshmi, R. Sudha, V. Manohar Nesakumar, S. Bharathiraja, T. Lavanya, J. Swaminathan, S. Ramachandran, G. Tags: ORIGINAL ARTICLES Source Type: research

Pharmacokinetics of thrice-weekly rifampicin, isoniazid and pyrazinamide in adult tuberculosis patients in India
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Hemanth Kumar, A. K. Kannan, T. Chandrasekaran, V. Sudha, V. Vijayakumar, A. Ramesh, K. Lavanya, J. Swaminathan, S. Ramachandran, G. Tags: ORIGINAL ARTICLES Source Type: research

Genetic polymorphisms of CCL2 associated with susceptibility to latent tuberculous infection in Thailand
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Nonghanphithak, D. Reechaipichitkul, W. Namwat, W. Lulitanond, V. Naranbhai, V. Faksri, K. Tags: ORIGINAL ARTICLES Source Type: research

Surveillance provides insight into epidemiology and spectrum of culture-confirmed mycobacterial disease in children
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Schaaf, H. S. Garcia-Prats, A. J. du Preez, K. Rautenbach, C. Hesseling, A. C. Tags: ORIGINAL ARTICLES Source Type: research

Combined approach to the identification of clinically infrequent non-tuberculous mycobacteria in Argentina
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Monteserin, J. Paul, R. Lopez, B. Cnockaert, M. Tortoli, E. Men éndez, C. Garc ía, M. J. Palomino, J. C. Vandamme, P. Ritacco, V. Martin, A. Tags: ORIGINAL ARTICLES Source Type: research

Chronic respiratory disease and high altitude are associated with depressive symptoms in four diverse settings
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Zaeh, S. Miele, C. H. Putcha, N. Gilman, R. H. Miranda, J. J. Bernabe-Ortiz, A. Wise, R. A. Checkley, W. Tags: ORIGINAL ARTICLES Source Type: research

Introduction of spirometry into clinical practice in Georgetown, Guyana: quality and diagnostic outcomes
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Johnston, J. C. Rempel, C. Sanders, C. Piggott, E. Maxwell, Y. Jaipersaud, K. Luknauth, R. Persaud, D. Rambaran, M. Levy, R. D. Tags: ORIGINAL ARTICLES Source Type: research

Isoniazid minimal inhibitory concentrations of tuberculosis strains with katG mutation
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Otto-Knapp, Ralf Vesenbeckh, Silvan Sch önfeld, Nicolas Bettermann, Gudrun Roth, Andreas Bauer, Torsten R üssmann, Holger Mauch, Harald Tags: CORRESPONDENCE Source Type: research

Reversion of phenotypic fluoroquinolone resistance in Mycobacterium tuberculosis
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Eilertson, Brandon Maruri, Fernanda Blackman, Amondrea Herrera, Miguel Sterling, Timothy R. Tags: CORRESPONDENCE Source Type: research

Endobronchial valves to treat a recurrent giant emphysematous bulla after bullectomy
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Ding, Mei Gao, Ya-Dong Dai, Li Li, Xin Yang, Jiong Tags: CORRESPONDENCE Source Type: research

The Effect of Growing Rod Treatment on Hemoglobin and Hematocrit Levels in Early-onset Scoliosis
Conclusions: Following distraction-based GR treatment of children with EOS there was a significant decrease in both their Hgb and Hct. This is a physiological marker of decreased hypoxemia and improved pulmonary function. Level of Evidence: Level III—therapeutic study. (Source: Journal of Pediatric Orthopaedics)
Source: Journal of Pediatric Orthopaedics - August 11, 2016 Category: Orthopaedics Tags: Spine Source Type: research

Living With Chronic Obstructive Pulmonary Disease: The Process of Self-Managing Chronic Obstructive Pulmonary Disease
Conclusions/Implications for Practice: Patients naturally become experts with regard to their lives through a process of trial and error. Even so, healthcare professionals play a key role in the process of self-management and help patients with COPD cope with various problems in their daily lives. The findingsof this study contribute to the development of evidence-based self-management interventions that promote quality of life in patients with COPD. (Source: Journal of Nursing Research)
Source: Journal of Nursing Research - August 11, 2016 Category: Nursing Tags: Original Articles Source Type: research

Two Hours of Teamwork Training Improves Teamwork in Simulated Cardiopulmonary Arrest Events
This study assessed the effectiveness of a 2-hour teamwork training program. Design: A prospective, pretest/posttest, quasi-experimental design assessed the teamwork training program targeted to resident physicians, nurses, and respiratory therapists. Methods: Participants took part in a simulated cardiac arrest. After the simulation, participants and trained observers assessed perceptions of teamwork using the Team Emergency Assessment Measure (TEAM) tool (ratings of 0 [low] to 4 [high]). A debriefing and 45 minutes of teamwork education followed. Participants then took part in a second simulated cardiac arrest scenario...
Source: Clinical Nurse Specialist - August 11, 2016 Category: Nursing Tags: Feature Article Source Type: research

Hospitalization With Infection May Increase Long-Term Risk Suicide
Patients who have been hospitalized with infections may be at an increased risk of death by suicide, according to astudy published Wednesday inJAMA Psychiatry. The findings add to a growing body of evidence supporting a link between infection, inflammation, psychiatric disorders, and suicidal behaviors. To investigate the associations between infectious diseases and the long-term risk of death by suicide, a team of researchers from Denmark and the United States analyzed data contained in Danish registers on more than 7 million people 15 years or older over a 32-year follow-up period. The study authors defined a h...
Source: Psychiatr News - August 11, 2016 Category: Psychiatry Tags: Danish registers Helene Lund-Sorensen HIV/AIDS hospitalization infection infectious disease JAMA Psychiatry Jamie Grit Lena Brundin suicide Source Type: research

Risk factors for post-operative respiratory failure among 94,621 neurosurgical patients from 2006 to 2013: a NSQIP analysis
ConclusionsBased on the NSQIP database, risk factors for respiratory failure after neurosurgery include pre-operative ventilator dependence, alcohol use, functional dependence prior to surgery, stroke, and recent operation. The overall rate of respiratory failure decreased from 4.1  % in 2006 to 2.1 % in 2013 according to these data. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - August 11, 2016 Category: Neurosurgery Source Type: research

Cluster of atypical adult Guillain-Barr é syndrome temporally associated with neurological illness due to EV-D68 in children, South Wales, United Kingdom, October 2015 to January 2016.
We report a cluster of atypical Guillain-Barré syndrome in 10 adults temporally related to a cluster of four children with acute flaccid paralysis, over a 3-month period in South Wales, United Kingdom. All adult cases were male, aged between 24 and 77 years. Seven had prominent facial diplegia at onset. Available electrophysiological studies showed axonal involvement in five adults. Seven reported various forms of respiratory disease before onset of neurological symptoms. The ages of children ranged from one to 13 years, three of the four were two years old or younger. Enterovirus testing is available for three children; ...
Source: Euro Surveill - August 11, 2016 Category: Infectious Diseases Authors: Williams CJ, Thomas RH, Pickersgill TP, Lyons M, Lowe G, Stiff RE, Moore C, Jones R, Howe R, Brunt H, Ashman A, Mason BW Tags: Euro Surveill Source Type: research

Pain after Major Craniotomy in a University Hospital: A Prospective Cohort Study.
CONCLUSION: Incidence of pain after craniotomy was high especially in younger age group, which is not in accordance with all similar reports. However we believe pain management after major craniotomy in our hospital requires improvement. PMID: 27501609 [PubMed - in process] (Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet)
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - August 11, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

Anesthetic Management for Esophageal Stent Placement in an Endoscopy Unit Outside Operating Room.
CONCLUSION: All of the esophageal stent placement procedures, general anesthesia and intravenous sedation techniques could be performed effectively in the appropriate patients. However, clinical signs should be carefully observed and the anesthetic personnel had to optimize the patient's condition for safety and beware of complications. PMID: 27501607 [PubMed - in process] (Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet)
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - August 11, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

The Efficacy of Two Oxygen Therapy Devices (Nasal Cannula vs. Simple Mask) for Preventing Hypoxemia after General Anesthesia: A Randomized Controlled Non-Inferiority Trial of 500 Patients.
CONCLUSION: In low risk patients undergoing low risk operations, both nasal cannula or simple mask with FiO₂ = 0.35 are equally effective for preventing hypoxemia in PACU. PMID: 27501599 [PubMed - in process] (Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet)
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - August 11, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

Comparison of Spraying and Nebulized Lidocaine in Patients Undergoing Esophago-Gastro-Duodenoscopy: A Randomized Trial.
CONCLUSION: The endoscopist expressed her approval of spraying lidocaine for taking less time to start the procedure, ease for instrumentation, less gag reflex during the procedure, less presence of hypersecretion, and smooth operation. However participants favored nebulized lidocaine administration. PMID: 27501598 [PubMed - in process] (Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet)
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - August 11, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

Systematic review and network meta-analysis of stroke prevention treatments in patients with atrial fibrillation
(Source: International Journal of COPD)
Source: International Journal of COPD - August 11, 2016 Category: Respiratory Medicine Tags: Clinical Pharmacology: Advances and Applications Source Type: research

Reduction of Streptococcus pneumoniae in upper respiratory tract cultures and a decreased incidence of related acute otitis media following introduction of childhood pneumococcal conjugate vaccines in a Swedish county
The effect of pneumococcal conjugate vaccines (PCV) on invasive pneumococcal disease is frequently reported, but the impact on upper respiratory tract infections in a clinical setting is less documented. Our a... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - August 11, 2016 Category: Infectious Diseases Authors: Nils Littorin, Jonas Ahl, Fabian Udd én, Fredrik Resman and Kristian Riesbeck Source Type: research

Acute Management of Paradoxical Vocal Fold Motion (Vocal Cord Dysfunction)
This article aims to summarize the ED presentation and management of paradoxical vocal fold motion. (Source: Annals of Emergency Medicine)
Source: Annals of Emergency Medicine - August 11, 2016 Category: Emergency Medicine Source Type: research

Pseudooutbreak of rapidly growing mycobacteria due to Mycobacterium abscessus subsp bolletii in a digestive and respiratory endoscopy unit caused by the same clone as that of a countrywide outbreak
Discussion Cross-transmission due to poor disinfection as well as resistance to glutaraldehyde may play roles in the spread of MAB01 M abscessus subsp bolletii, which may have a unique resistance to the environment and adaption to human hosts. However the water supply may have played a role. Attention is needed to ensure the quality of water used to rinse disinfected equipment. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - August 11, 2016 Category: Infectious Diseases Source Type: research

Determinants of patients’ needs in asthma treatment: a cross-sectional study
npj Primary Care Respiratory Medicine, Published online: 11 August 2016; doi:10.1038/npjpcrm.2016.44 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - August 11, 2016 Category: Primary Care Authors: Adrian Loerbroks Aziz Sheikh Verena Leucht Christian J Apfelbacher Andrea Icks Peter Angerer Source Type: research

Evaluation of some pulmonary functions and pleuropulmonary complications after endoscopic sclerotherapy of gastric fundal varices at Zagazig university hospitals
Conclusions NBCA injection of gastric fundal varices was associated with significant, reversible deterioration in some pulmonary functions, atelectasis and minimal pleural effusion with significant rapid improvement if incentive spirometry is used. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - August 11, 2016 Category: Respiratory Medicine Source Type: research

Cerebral Microvascular Blood Flow and CO2 Reactivity in Pulmonary Arterial Hypertension
In conclusion, CBFmicr and CVRCO2 are lessened in clinically stable, mildly-impaired patients with PAH. These abnormalities might be associated with relevant clinical outcomes (hyperventilation and dyspnea, cognition, cerebrovascular disease) being potentially amenable to pharmacological treatment. (Source: Respiratory Physiology and Neurobiology)
Source: Respiratory Physiology and Neurobiology - August 11, 2016 Category: Respiratory Medicine Source Type: research

Adaptations in limb muscle function following pulmonary rehabilitation in patients with COPD – a review
Publication date: Available online 11 August 2016 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): André Nyberg, João Carvalho, Kim-Ly Bui, Didier Saey, François Maltais Even though chronic obstructive pulmonary disease (COPD) is primarily a disease of the respiratory system, limb muscle dysfunction characterized by muscle weakness, reduced muscle endurance and higher muscle fatigability, is a common secondary consequence and a major systemic manifestation of the disease. Muscle dysfunction is especially relevant in COPD because it is related to important clinical outcomes such as mortality, qualit...
Source: Revista Portuguesa de Pneumologia - August 11, 2016 Category: Respiratory Medicine Source Type: research

Simple and practical measures to reduce tuberculosis transmission in public buildings
This article is currently available as a free download on Ingenta Connect (Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - August 11, 2016 Category: Respiratory Medicine Authors: Scardigli, Anna Caminero, Jose A. Tags: EDITORIALS Source Type: research

Effects of clinical pathways for chronic obstructive pulmonary disease (COPD) on patient, professional and systems outcomes: protocol for a systematic review
DiscussionThe systematic review outlined in this protocol aims to identify, assess and synthesise all available evidence on the effects of CPWs regarding the treatment and management of COPD. As a result, this review will provide an evidence base for decision makers regarding the practicality, cost effectiveness, patient benefit and best practices regarding the implementation of CPWs for the care of COPD. (Source: Systematic Reviews)
Source: Systematic Reviews - August 11, 2016 Category: Global & Universal Source Type: research

Acute respiratory failure in scrub typhus patients
Jyoti Narayan Sahoo, Mohan Gurjar, Yogesh Harde HardeIndian Journal of Critical Care Medicine 2016 20(8):480-484Respiratory failure is a serious complication of scrub typhus. In this prospective study, all patients with a diagnosis of scrub typhus were included from a single center Intensive Care Unit (ICU). Demographic, clinical characteristics, laboratory, and imaging parameters of these patients at the time of ICU admission were compared. Of the 55 scrub typhus patients, 27 (49%) had an acute respiratory failure. Seventeen patients had acute respiratory distress syndrome, and ten had cardiogenic pulmonary edema. ...
Source: Indian Journal of Critical Care Medicine - August 11, 2016 Category: Intensive Care Authors: Jyoti Narayan Sahoo Mohan Gurjar Yogesh Harde Harde Source Type: research

The obligate respiratory supercomplex from Actinobacteria
Publication date: October 2016 Source:Biochimica et Biophysica Acta (BBA) - Bioenergetics, Volume 1857, Issue 10 Author(s): Wei-Chun Kao, Thomas Kleinschroth, Wolfgang Nitschke, Frauke Baymann, Yashvin Neehaul, Petra Hellwig, Sebastian Richers, Janet Vonck, Michael Bott, Carola Hunte Actinobacteria are closely linked to human life as industrial producers of bioactive molecules and as human pathogens. Respiratory cytochrome bcc complex and cytochrome aa 3 oxidase are key components of their aerobic energy metabolism. They form a supercomplex in the actinobacterial species Corynebacterium glutamicum. With comprehensive bioi...
Source: Biochimica et Biophysica Acta (BBA) Bioenergetics - August 11, 2016 Category: Biochemistry Source Type: research

Absorbance and redox based approaches for measuring free heme and free hemoglobin in biological matrices
In this study, we developed and validated a new approach based on absorbance spectrum deconvolution with least square fitting analyses that overcomes these limitations and simultaneously measures CFH and Hb in simple aqueous buffers, plasma or when associated with red cell derived microvesicles. We show how incorporating other plasma factors that absorb light over the visible wavelength range (specifically bilirubin), coupled with truncating the wavelength range analyzed, or addition of mild detergent significantly improves fits allowing measurement of oxyHb, CFH and metHb with >90% accuracy. When this approach was ...
Source: Redox Biology - August 11, 2016 Category: Biology Source Type: research

Enhancement of innate immunity with granulocyte colony-stimulating factor did not mitigate disease in pigs infected with a highly pathogenic Chinese PRRSV strain
Publication date: Available online 10 August 2016 Source:Veterinary Immunology and Immunopathology Author(s): Sarah N. Schlink, Kelly M. Lager, Susan L. Brockmeier, Crystal L. Loving, Laura C. Miller, Ann C. Vorwald, Han-Chun Yang, Marcus E. Kehrli, Kay S. Faaberg Porcine reproductive and respiratory syndrome virus (PRRSV) is responsible for one of the most economically important diseases in swine worldwide. It causes reproductive failure in sows and pneumonia in pigs that predisposes them to secondary bacterial infections. Methods to control PRRSV and/or limit secondary bacterial infections are desired to reduce the impa...
Source: Veterinary Immunology and Immunopathology - August 11, 2016 Category: Veterinary Research Source Type: research

Procalcitonin: A new biomarker for the Cardiologist
Due to its high accuracy for the diagnosis of bacterial infections, the inflammatory biomarker procalcitonin (PCT) is increasingly being used in patients with suspected infection. In patients with infections of the respiratory tract, it allows rapid rule out of bacterial etiology and facilitates decisions pertaining to antibiotic management. A growing body of evidence also supports PCT testing in patients with cardiovascular disorders including, but not limited to, those with shortness of breath, possible heart failure, suspected endocarditis, and acute coronary syndromes. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - August 11, 2016 Category: Cardiology Authors: Philipp Schuetz, Lori B. Daniels, Prasad Kulkarni, Stefan D. Anker, Beat Mueller Source Type: research

Imaging of Acute Lung Injury
This article discusses the multidisciplinary diagnosis of ALI from the perspective of the imager. (Source: Radiologic Clinics of North America)
Source: Radiologic Clinics of North America - August 11, 2016 Category: Radiology Authors: Brett M. Elicker, Kirk T. Jones, David M. Naeger, James A. Frank Source Type: research

Pulmonary cryptococcosis mimicking a metastasis in a patient with Ewing sarcoma
Cryptococcosis is an invasive fungal infection that is common in immunocompromised patients. A 22‐year‐old woman with Ewing sarcoma in the right proximal humerus was treated by resection and chemotherapy. Computed tomography detected a small nodule in her right upper pulmonary lobe after completion of her chemotherapy. With the presumptive diagnosis of pulmonary metastasis, she underwent resection. Evaluation of the resected specimen revealed pulmonary cryptococcosis, and the patient was treated with oral fluconazole for 18 weeks. Extensive chemotherapy for high‐grade sarcoma is a possible risk factor for pulmonary c...
Source: Respirology Case Reports - August 11, 2016 Category: Respiratory Medicine Authors: Akio Sakamoto, Masanori Hisaoka Tags: Case Report Source Type: research

Respiratory pathogen colonisation of dental plaque, the lower airways and endotracheal tube biofilms during mechanical ventilation
In mechanically ventilated patients, the endotracheal tube is an essential interface between the patient and ventilator, but inadvertently it also facilitates the development of ventilator-associated pneumonia (VAP) by subverting pulmonary host defense. A number of investigations suggest that bacteria colonising the oral cavity may be important in the aetiology of VAP. The present study evaluated microbial changes that occurred in dental plaque and lower airways of 107 critically ill mechanically ventilated patients. (Source: Journal of Critical Care)
Source: Journal of Critical Care - August 11, 2016 Category: Intensive Care Authors: Kirsty M. Sands, Melanie J. Wilson, Michael A.O. Lewis, Matt P. Wise, Nicki Palmer, Anthony J. Hayes, Rosemary A. Barnes, David W. Williams Source Type: research

One-year resource utilisation, costs and quality of life in patients with acute respiratory distress syndrome (ARDS): secondary analysis of a randomised controlled trial
ConclusionsGiven the high costs and low health-related quality of life identified, there is significant scope for further research aimed at improving care in this in-need patient group.Trial registrationISRCTN10416500 (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - August 11, 2016 Category: Intensive Care Source Type: research

ARDS Subphenotypes Respond Differently to Randomized Fluid Management Strategy.
Abstract BACKGROUND: We previously identified two ARDS subphenotypes in two separate randomized controlled trials, with differential response to positive end-expiratory pressure. The current analysis sought to identify these subphenotypes in a third ARDS cohort, to test whether subphenotypes respond differently to fluid management strategy, and to develop a practical model for subphenotype identification. METHODS:  We used latent class analysis of baseline clinical and plasma biomarker data to identify subphenotypes in the Fluid and Catheter Treatment Trial (FACTT; n=1000). Logistic regression was used to te...
Source: American Journal of Respiratory and Critical Care Medicine - August 11, 2016 Category: Respiratory Medicine Authors: Famous KR, Delucchi K, Ware LB, Kangelaris KN, Liu KD, Thompson BT, Calfee CS Tags: Am J Respir Crit Care Med Source Type: research