The Genetic Determinants of Axial Length: From Microphthalmia to High Myopia in Childhood
Annu Rev Genomics Hum Genet. 2023 Aug 25;24:177-202. doi: 10.1146/annurev-genom-102722-090617.ABSTRACTThe axial length of the eye is critical for normal visual function by enabling light to precisely focus on the retina. The mean axial length of the adult human eye is 23.5 mm, but the molecular mechanisms regulating ocular axial length remain poorly understood. Underdevelopment can lead to microphthalmia (defined as a small eye with an axial length of less than 19 mm at 1 year of age or less than 21 mm in adulthood) within the first trimester of pregnancy. However, continued overgrowth can lead to axial high myopia (an enl...
Source: Annual Review of Genomics and Human Genetics - August 25, 2023 Category: Genetics & Stem Cells Authors: Daniel Jackson Mariya Moosajee Source Type: research

Acuity 200 ™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Condition:   Myopia Intervention:   Device: Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear Sponsor:   Acuity Polymers, Inc. Not yet recruiting
Source: ClinicalTrials.gov - August 24, 2023 Category: Research Source Type: clinical trials

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