Ocular manifestations of the genetic causes of focal and segmental glomerulosclerosis
This study examined FSGS-associated genes from the Genomics England Renal proteinuria panel  for reported and likely ocular features. Thirty-two of the 55 genes (58%) were associated with ocular abnormalities in human disease, and a further 12 (22%) were expressed in the retina or had an eye phenotype in mouse models. The commonest genes affected in congenital nephrotic syndrome (NPHS1,NPHS2,WT1,LAMB2,PAX2 but notPLCE1) may have  ocular manifestations . Many genes affected in childhood–adolescent onset FSGS (NPHS1,NPHS2,WT1,LAMB2,SMARCAL1,NUP107 but notTRPC6 orPLCE1) have ocular features. The commonest genes affected ...
Source: Pediatric Nephrology - August 14, 2023 Category: Urology & Nephrology Source Type: research

Postoperative Refractive Outcomes of Biometric Formulas in Phacovitrectomy with Gas Tamponade
CONCLUSIONS: Our study did not find evidence for superiority of any formula in phacovitrectomy. However, in phacovitrectomy, possible myopic shift should be considered for IOL power calculation. Especially, in phacovitrecotmy in patients with high myopia, more myopic shift should be considered when selecting IOL.PMID:37563972 | DOI:10.3341/kjo.2023.0012
Source: Korean Journal of Ophthalmology : KJO - August 11, 2023 Category: Opthalmology Authors: Yu-Jin Choi Donghyun Jee Source Type: research

Comparison of visual performance and image quality between a myopia-control contact lens and a single-vision contact lens
This study aimed to evaluate the visual performance and image quality of concentric dual-focus-designed contact lenses (CLs) compared with single-vision CLs in myopic Chinese people.
Source: Contact Lens and Anterior Eye - August 11, 2023 Category: Opthalmology Authors: Ding Han, Ziyu Zhang, Bingqin Li, Hua Rong, Desheng Song, Bei Du, Ruihua Wei Source Type: research

Quantization of Optic Disc Characteristics in Young Adults Based on Artificial Intelligence
CONCLUSION: The characteristics of the optic disc can be feasibly and efficiently extracted using AI. The quantization of the optic disc might provide new indicators for clinicians to evaluate the degree of myopia.PMID:37555317 | DOI:10.1080/02713683.2023.2244700
Source: Current Eye Research - August 9, 2023 Category: Opthalmology Authors: Xiaoxiao Guo Runkuan Li Xiuzhen Lu Xiuyan Zhang Qiuxin Wu Qingmei Tian Bin Guo Guodong Tang Jing Xu Jiaojiao Feng Lili Zhao Saiguang Ling Zhou Dong Jike Song Hongsheng Bi Source Type: research

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