Association between nesfatin-1 hormone levels, anthropometric measurements, and glucose regulation shortly after sleeve gastrectomy: A  cross-sectional study
ConclusionsThis finding highlights the anorexigenic effects of nesfatin-1, and therefore, nesfatin-1 may be an effective factor in obesity treatment and diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 11, 2023 Category: Endocrinology Source Type: research

High expression of the glutathione S-transferase A2 and neuropilin-2 genes affects pancreatic islet β-cell function
ConclusionsThe results suggest that Nrp2 regulates apoptosis in Min6 cells and that there may be a link between this molecule and pathological apoptosis of pancreatic β-cells in T2DM patients. However, Gsta2 was not found to be an upstream regulator of Nrp2 in our cell line. Therefore, Gsta2 regulation of apoptosis in Min6 cells may be achieved through other apoptotic pathways. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 6, 2023 Category: Endocrinology Source Type: research

Multivariable prediction model of complications derived from diabetes mellitus using machine learning on scarce highly unbalanced data
ConclusionsThis ML model can be applied to predict CHD, CKD, and MOR. The success of ML predictions lies in the clinical definition of initial variables and their simplification for obtaining variables based on which the algorithms can identify patients that are likely to develop a complication. For clinical application of this system, it is necessary to assess the cross performance of metrics, as found here (accuracy higher 95% and F1-Score higher than 80%). (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 26, 2023 Category: Endocrinology Source Type: research

Inflammatory potential of the diet is associated with psychological stress in adults with type 2 diabetes: a methodological approach of e-Health
ConclusionUsing e-Health through web-based tools to collect information showed benefits of the application as a method of dietary assessment. We provide evidence showing that better values of the DII score and physical activity may play a protective role against the presence of psychological stress; DII and E-DII scores qualify and label habitual diet into pro and anti-inflammatory and are associated with psychological stress in T2D. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 23, 2023 Category: Endocrinology Source Type: research

Effects of exercises and manual therapy on nerve conduction studies of lower limb in patients with diabetes and diabetic peripheral neuropathy: A systematic review
ConclusionThe present systematic review suggests that 8 to 12  weeks of physical exercise improves nerve conduction velocity of the motor tibial, peroneal nerve, and sensory sural nerve in diabetes with or without peripheral neuropathy. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 23, 2023 Category: Endocrinology Source Type: research

Effectiveness and safety of Glargine U-100 and detemir insulin in hyperglycemic pregnancy: a record-based observational study
ConclusionThe study concluded that glargine U-100 may be a preferred treatment option for hyperglycemic pregnancy. Further studies are needed for optimizing treatment strategies in hyperglycemic pregnancies. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 23, 2023 Category: Endocrinology Source Type: research

Don ’t let the “Pre” of Prediabetes fool you!
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 21, 2023 Category: Endocrinology Source Type: research

Prevalence of thyroid nodule and its association with β-cell autoantibodies in adult patients with type 1 diabetes mellitus without thyroid dysfunction
ConclusionA relationship was observed between ICA positivity and thyroid nodules in T1DM. Thus, cases with ICA positivity may have a higher probability of nodules in the thyroid gland, and neck examinations should be performed more frequently. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 18, 2023 Category: Endocrinology Source Type: research

Correlation between triglyceride-glucose index and related parameters and nonalcoholic fatty liver disease in northwest China
ConclusionsThis study demonstrated that TyG and its related parameters are significantly correlated with NAFLD. TyG-BMI is an effective predictor or clinical marker for identifying NAFLD. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 14, 2023 Category: Endocrinology Source Type: research

Diagnosis of latent autoimmune diabetes after SARS –Cov2 vaccination in adult patients previously diagnosed with type 2 diabetes mellitus
ConclusionIn case of impaired glycemic control after SARS-CoV-2 vaccination in a well-controlled diabetic patient, LADA should be considered. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 13, 2023 Category: Endocrinology Source Type: research

Severe hypoglycemia due to insulin auto-antibodies of newly diagnosed multiple myeloma: A case report
ConclusionIAS should be considered in the differential diagnosis of recurrent hypoglycemia cases of unknown cause. It should be kept in mind that IAS may develop due to multiple myeloma, especially in patients with advanced age and anemia. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 13, 2023 Category: Endocrinology Source Type: research

Analysis of the gut microflora in women with gestational diabetes mellitus
ConclusionIn this study, the abundance and diversity of the intestinal floras were similar in both women with GDM and healthy pregnant women. Conversely, the specificities of the intestinal floras were significantly different between the two groups, with a relative decrease in the abundance ofActinobacteria and thick-walled phyla and a relative increase in the abundance ofAspergillus andBacteroides phyla. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 11, 2023 Category: Endocrinology Source Type: research

Isocaloric diet is as effective as the hypocaloric diet in ameliorating symptoms in PCOS patients
ConclusionHCD and ICHD are equally effective in as many as 30% patients with mild symptoms over long term. Patients having higher caloric intakes at baseline should not be offered isocaloric diets. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 11, 2023 Category: Endocrinology Source Type: research

Genetic screening for pathogenic variants in type 2 diabetes of the Arab Gulf population: A systematic review and meta-analysis
ConclusionFor a better understanding of the molecular etiology of T2DM, finding SNPs, and establishing a meaningful genotype-phenotype connection for complicated diabetic disorders, the cumulative relevance of identified pathogenic SNPs in Arab Gulf was shown. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 11, 2023 Category: Endocrinology Source Type: research

β cell function and insulin resistance have gender-specific correlations with carotid intima-media thickness in type 2 diabetes
ConclusionEarly insulin response stimulated by arginine is independently associated with C-IMT in women T2D individuals, whereas insulin resistance is positively correlated with C-IMT in men T2D subjects. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 9, 2023 Category: Endocrinology Source Type: research