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Prevalence and determinants of metabolic syndrome: a cross-sectional survey of general medical outpatient clinics using National Cholesterol Education Program-Adult Treatment Panel III criteria in Botswana
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - August 30, 2016 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Comparison of coronary heart disease risk among four diagnostic definitions of metabolic syndrome
ConclusionsThese findings suggest that further studies are required to establish appropriate criteria of MetS in females. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - August 29, 2016 Category: Endocrinology Source Type: research

Cardiorespiratory fitness effect may be underestimated in "fat but fit" hypothesis studies.
CONCLUSION: These findings suggest that body fat is strongly related to cardiovascular risk, but when the outcome is calculated without the central obesity indicator, cardiorespiratory fitness becomes more related to metabolic risk. PMID: 27562242 [PubMed - as supplied by publisher] (Source: Annals of Human Biology)
Source: Annals of Human Biology - August 28, 2016 Category: Biology Tags: Ann Hum Biol Source Type: research

Cardiometabolic Risks in Schizophrenia and Directions for Intervention, 2: Nonpharmacological Interventions.
Authors: Andrade C Abstract Patients with schizophrenia have increased prevalence rates for many cardiometabolic risks, including the metabolic syndrome, and an increased risk of adverse cardiovascular events, including mortality. Behavioral interventions such as diet and exercise (separately and together) improve physical health outcomes in the general population. There are no studies on dietary guidance as a sole behavioral intervention for patients with schizophrenia. A meta-analysis found that exercise as a sole behavioral intervention does not result in meaningful physical or mental health gains in patients wi...
Source: Journal of Clinical Psychiatry - August 28, 2016 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Non-Obese Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) refers to a group of conditions characterized by hepatic steatosis in the absence of significant alcohol consumption. NAFLD is commonly seen in patients with metabolic abnormalities associated with obesity, such as type II diabetes, dyslipidemia, and metabolic syndrome. Evidently, however, not all obese subjects develop NAFLD and, more importantly, NAFLD can be found in non-obese individuals. While NAFLD occurring in non-obese subjects has been reported in children and adults of all ethnicities, it appears to be recognized more frequently in Asians, even when strict ethnicity-specif...
Source: Clinical Gastroenterology and Hepatology - August 28, 2016 Category: Gastroenterology Authors: Donghee Kim, W. Ray Kim Source Type: research

Increased angiopoietin-like protein 8 levels in patients with type 2 diabetes and cardiovascular disease
Angiopoietin-like protein 8 (ANGPTL 8), also known as lipasin and betatrophin, was first found to be linked with lipid metabolism [1]. In the last 3 years there has been a surge of interest in assessing ANGPTL 8 levels in different pathophysiological conditions including dyslipidemia, obesity, diabetes, non-alcoholic fatty liver disease, and metabolic syndrome [2 –7], well-recognized risk factors for atherosclerosis and cardiovascular disease (CVD). However, the association between ANGPTL 8 and CVD is unknown; therefore, the purpose of the present study was to assess ANGPTL 8 levels in patients with diabetes and evaluate...
Source: Diabetes Research and Clinical Practice - August 28, 2016 Category: Endocrinology Authors: Yun Huang, Chen Fang, Heming Guo, Ji Hu Source Type: research

Actual lowering effect of metabolic syndrome on serum prostate ‐specific antigen levels is partly concealed by enlarged prostate: results from a large‐scale population‐based study
ConclusionThe actual lowering effect of MetS on serum PSA levels was partly concealed by the enlarged prostate in men with MetS, and the presence of MetS was independently associated with lower serum PSA levels. Urologists need to be aware of the effect of MetS on serum PSA levels and should discuss this subject with their patients. (Source: BJU International)
Source: BJU International - August 28, 2016 Category: Urology & Nephrology Authors: Sicong Zhao, Ming Xia, Jianchun Tang, Yong Yan Tags: Original Article Source Type: research

Omega-3 fatty acid supplementation influences the whole blood transcriptome in women with obesity, associated with pro-resolving lipid mediator production
Publication date: November 2016 Source:Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Volume 1861, Issue 11 Author(s): Anna Polus, Barbara Zapala, Urszula Razny, Anna Gielicz, Beata Kiec-Wilk, Malgorzata Malczewska-Malec, Marek Sanak, Caroline E. Childs, Philip C. Calder, Aldona Dembinska-Kiec The n-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may reduce low-grade inflammation associated with obesity. The relationship between therapeutic response to n-3 PUFAs and modification of the transcriptome in obesity or metabolic syndrome remains to be...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - August 28, 2016 Category: Lipidology Source Type: research

Gene polymorphisms of desaturase enzymes of polyunsaturated fatty acid metabolism and adiponutrin and the increased risk of nonalcoholic fatty liver disease
In conclusion, this study showed a novel association of FADS2 gene polymorphisms with NAFLD. It also verified the previously established association of rs738409 polymorphism with NAFLD. (Source: Meta Gene)
Source: Meta Gene - August 28, 2016 Category: Genetics & Stem Cells Source Type: research

Defining Metabolic Syndrome and Factors Associated with Metabolic Syndrome in a Poly-pharmaceutical Population.
CONCLUSION: The IDF definition for METs that makes allowance for treatment for each specific condition can lead to an overestimation in the prevalence of METs in population studies. Not including those medicated with normal results conversely underestimates the prevalence of METs. We have therefore proposed adjustments to BP and lipid measurements based on pooled mean effects from published systematic reviews to mitigate bias in future research on prevalence of METs. PMID: 27558757 [PubMed - as supplied by publisher] (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - August 27, 2016 Category: Internal Medicine Tags: Postgrad Med Source Type: research

Adherence to the Mediterranean diet is inversely associated with metabolic syndrome occurrence: a meta-analysis of observational studies.
In conclusion, adoption of a Mediterranean dietary pattern was associated with lower risk of the MetS and it can be proposed for the primary prevention of the MetS. PMID: 27557591 [PubMed - as supplied by publisher] (Source: International Journal of Food Sciences and Nutrition)
Source: International Journal of Food Sciences and Nutrition - August 27, 2016 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research

Therapeutic potential of naringin: an overview.
CONCLUSION: Naringin is a promising candidate for further in vivo studies and clinical use. More detailed studies regarding its mechanism of action are required. PMID: 27564838 [PubMed - as supplied by publisher] (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 27, 2016 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research

Comparison of clinical and biochemical variables in type 2 diabetes mellitus patients and their first-degree relatives with metabolic syndrome in Benin City, Nigeria: A cross sectional case controlled study.
CONCLUSION: The prevalence of MetS in subjects with T2DM in Nigeria is very high. Though, all the biochemical and clinical indices were higher in T2DM subjects with MetS, the mean HbA1c, BMI, and SBP was significantly higher when compared to their FDR who also have MetS. PMID: 27560635 [PubMed - in process] (Source: Endocrine Regulations)
Source: Endocrine Regulations - August 27, 2016 Category: Endocrinology Tags: Endocr Regul Source Type: research

Early diabetes screening in women with previous gestational diabetes: a new insight
Gestational diabetes mellitus (GDM) is a risk factor for the development of diabetes mellitus (DM). However, there is a low return rate for this screening, so it is important to search for earlier methods for ... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - August 27, 2016 Category: Endocrinology Authors: Aline Nabuco, Samara Pimentel, Carolina A. Cabizuca, Melanie Rodacki, Denise Finamore, Marcus M. Oliveira and Lenita Zajdenverg Source Type: research

Reduced circulating adiponectin levels are associated with the metabolic syndrome independently of obesity, lipid indices and serum insulin levels: a cross-sectional study
Given the increasing rate of overweight and the burden of metabolic syndrome (MetS) on cardiovascular disease development, better understanding of the syndrome is of great importance. Therefore, the objectives... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - August 27, 2016 Category: Lipidology Authors: Agathi Ntzouvani, Elisabeth Fragopoulou, Demosthenes Panagiotakos, Christos Pitsavos and Smaragdi Antonopoulou Source Type: research

Role of pancreatic duct cell in beta cell neogenesis: A mini review study
Publication date: Available online 27 August 2016 Source:Diabetes & Metabolic Syndrome: Clinical Research & Reviews Author(s): Mahsa Zare, Shahdokht Rastegar, Esmaeel Ebrahimi, Azade Roohipoor, Saeed Shirali Today diabetes mellitus is known as main threatening for health society. Beta cells have pivotal role in energy homeostasis by balance in blood glucose. Proliferation and neogenesis are two factors for preservation of beta cell mass but these have lower rate during adulthood rather than neonatal. Beta cell destruction occurs during diabetes that leads to hyperglycemia. Continues production of beta cell...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 27, 2016 Category: Endocrinology Source Type: research

Role of Aryl Hydrocarbon Receptor in Circadian Clock Disruption and Metabolic Dysfunction.
Abstract The prevalence of metabolic syndrome, a clustering of three or more risk factors that include abdominal obesity, increased blood pressure, and high levels of glucose, triglycerides, and high-density lipoproteins, has reached dangerous and costly levels worldwide. Increases in morbidity and mortality result from a combination of factors that promote altered glucose metabolism, insulin resistance, and metabolic dysfunction. Although diet and exercise are commonly touted as important determinants in the development of metabolic dysfunction, other environmental factors, including circadian clock disruption an...
Source: Environmental Health Insights - August 26, 2016 Category: Environmental Health Authors: Jaeger C, Tischkau SA Tags: Environ Health Insights Source Type: research

Preoperative metabolic syndrome and prognosis after radical resection for colorectal cancer: The Fujian prospective investigation of cancer (FIESTA) study
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - August 26, 2016 Category: Cancer & Oncology Authors: Feng Peng, Dan Hu, Xiandong Lin, Gang Chen, Binying Liang, Hejun Zhang, Kaida Ji, Jun Huang, Jinxiu Lin, Xiongwei Zheng, Wenquan Niu Tags: Research Article Source Type: research

Sedentary bout durations and metabolic syndrome among working adults: a prospective cohort study
This study aimed to examine the associations between time spent in prolonged and non-prolonged sedentary bouts and the development of metabolic syndrome. (Source: BMC Public Health)
Source: BMC Public Health - August 26, 2016 Category: Consumer Health News Authors: Takanori Honda, Sanmei Chen, Koji Yonemoto, Hiro Kishimoto, Tao Chen, Kenji Narazaki, Yuka Haeuchi and Shuzo Kumagai Source Type: research

Common dysregulated pathways in obese adipose tissue and atherosclerosis
The metabolic syndrome is becoming increasingly prevalent in the general population that is at simultaneous risk for both type 2 diabetes and cardiovascular disease. The critical pathogenic mechanisms underlyi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 26, 2016 Category: Cardiology Authors: V. Moreno-Viedma, M. Amor, A. Sarabi, M. Bilban, G. Staffler, M. Zeyda and T. M. Stulnig Source Type: research

Colorimetric sensor based on bubble wrap and camera phone for glucose determination
Publication date: Available online 25 August 2016 Source:Journal of Applied Biomedicine Author(s): Pavla Martinkova, Miroslav Pohanka Glucose is a typical marker of diabetes mellitus but it corresponds also with metabolic syndrome, immune disorders and some types of poisoning. Hence fast, low cost and simple method for its determination is required. Bubble wrap, cheap and available material, was used for immobilization of glucose oxidase (GOx) and peroxidase (POx), the enzymes necessary for colorimetric determination of glucose. Method is based on reaction of enzymes (immobilized in sol-gel membrane inside the bubbles) wi...
Source: Journal of Applied Biomedicine - August 26, 2016 Category: Biotechnology Source Type: research

Beverage consumption and paediatric NAFLD.
Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children and adolescents, due to the increased worldwide incidence of obesity among children. It is now clear enough that of diet high in carbohydrates and simple sugars are associated with hepatic steatosis and non-alcoholic steatohepatitis (NASH). Several studies have shown that an increased consumption of simple sugars is also positively associated with overweight and obesity, and related co-morbidities, such as type 2 diabetes, metabolic syndrome and NAFLD. It is difficult to define the role of the various components...
Source: Eating and weight disorders : EWD - August 26, 2016 Category: Eating Disorders and Weight Management Authors: Mosca A, Della Corte C, Sartorelli MR, Ferretti F, Nicita F, Vania A, Nobili V Tags: Eat Weight Disord Source Type: research

Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the USP7/IRS1 Interaction
In this study, we demonstrate a role for the phosphate inorganic transporter 1 (PiT1/SLC20A1) in regulating metabolism. Specific knockout of Pit1 in hepatocytes significantly improved glucose tolerance and insulin sensitivity, enhanced insulin signaling, and decreased hepatic lipogenesis. We identified USP7 as a PiT1 binding partner and demonstrated that Pit1 deletion inhibited USP7/IRS1 dissociation upon insulin stimulation. This prevented IRS1 ubiquitination and its subsequent proteasomal degradation. As a consequence, delayed insulin negative feedback loop and sustained insulin signaling were observed. Moreover, PiT1-de...
Source: Cell Reports - August 26, 2016 Category: Cytology Source Type: research

Recurrent Preeclampsia in Women With Metabolic Syndrome and Low Plasma Volume: A Retrospective Cohort Study
(BJOG. 2015;122(13):1773–1780) Preeclampsia occurs in 2% to 8% of pregnancies and is associated with significant maternal and perinatal morbidity and mortality. Women with a history of preeclampsia are at increased risk for preeclampsia in subsequent pregnancies. The aim of this study was to determine the prevalence of recurrent preeclampsia in women who have been diagnosed with metabolic syndrome and/or low plasma volume compared with women who have a history of preeclampsia but neither of these pathologic conditions. (Source: Obstetric Anesthesia Digest)
Source: Obstetric Anesthesia Digest - August 25, 2016 Category: Anesthesiology Tags: Mother, Fetus, Neonate Source Type: research

Should psoriasis be considered a risk factor for hypogonadism in male patients? A monocentric, prospective, observational pilot study
This article is protected by copyright. All rights reserved. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - August 25, 2016 Category: Dermatology Authors: T. Hillary, J. Gutermuth Tags: Letter to Editor Source Type: research

The relationship between serum uric acid and metabolic syndrome in premenopausal and postmenopausal women in the Jinchang Cohort
. (Source: Gynecological Endocrinology)
Source: Gynecological Endocrinology - August 25, 2016 Category: Endocrinology Authors: Shi-Jiao He Cynthia Chan Zhi-Dong Xie Dian Shi Xiao-Bin Hu Hai-Yan Li Dennis Wang Min-Zhen Wang Ya-Na Bai Source Type: research

Predictors of self-care among the elderlies with diabetes type 2 using social cognitive theory
Conclusion Self-care behaviors in this study were poor. Therefore, it is necessary to develop an educational intervention based on cognitive theory constructs with the goal of properly managing diabetes in the elderly patients. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 25, 2016 Category: Endocrinology Source Type: research

Do worms protect against the metabolic syndrome? A systematic review & meta −analysis
Helminths have co −evolved with humans over the centuries; evolutionary theory would suggest some mutual benefit for both host and parasite. Publication of the “Hygiene Hypothesis” in 1989 sparked interest in the potential protective effects of helminth infections on human disease [1] and there is now a growing body of literature exploring the role of helminths in prevention and management of certain autoimmune and allergic conditions, including coeliac disease, inflammatory bowel disease, asthma, and type 1 diabetes (T1DM) [2–4]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - August 25, 2016 Category: Endocrinology Authors: Ella F. Tracey, Robyn A. McDermott, Malcolm I. McDonald Source Type: research

Examining the prevalence of metabolic syndrome among overweight/obese African-American breast cancer survivors vs. matched non-cancer controls
ConclusionsWhile MetS occurred less frequently in our BC cases vs. non-cancer controls, our estimates are nearly two times those reported in other BC survivors, suggesting important racial/ethnic differences.Implications for cancer survivorsThe prognostic implications of MetS among AA BC survivors remain unknown and warrant further investigation. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - August 25, 2016 Category: Cancer & Oncology Source Type: research

Pioglitazone Improves Aerobic Capacity and Skeletal Muscle Energy Metabolism in Patients with Metabolic Syndrome
Low aerobic capacity is a strong and independent predictor of all-cause mortality in patients with metabolic syndrome (MetS). The aim of the study was to investigate the effects of pioglitazone on aerobic capacity and skeletal muscle energy metabolism in patients with MetS. Fourteen patients with MetS participated in the study and received 15  mg/day pioglitazone for 4 months. To assess skeletal muscle energy metabolism, intramyocellular lipid (IMCL) in the resting leg and high-energy phosphates in the calf muscle during plantar-flexion exercise were measured using 1proton- and 31phosphorus-magnetic resonance spectroscop...
Source: Journal of Cardiac Failure - August 24, 2016 Category: Cardiology Authors: Takashi Yokota, Shintaro Kinugawa, Kagami Hirabayashi, Tadashi Suga, Shingo Takada, Koichi Okita, Hiroyuki Tsutsui Source Type: research

Dietary factors associated with metabolic syndrome and its components in overweight and obese Brazilian schoolchildren: a cross-sectional study
The metabolic syndrome (MS) has been assessed since childhood mainly because of the nutritional and epidemiological transition that has occurred worldwide. Our objectives were to explore the MS and its compone... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - August 24, 2016 Category: Endocrinology Authors: Ana Elisa Madalena Rinaldi, Gleice Fernanda Costa Pinto Gabriel, Fernando Moreto, Jos é Eduardo Corrente, Kátia Cristina Portero McLellan and Roberto Carlos Burini Source Type: research

β-Cell death is decreased in women with gestational diabetes mellitus
Gestational diabetes mellitus (GDM) affects approximately 7 –17 % of all pregnancies and has been recognized as a significant risk factor to neonatal and maternal health. Postpartum, GDM significantly increases... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - August 24, 2016 Category: Endocrinology Authors: Lauren A. Kenna, John A. Olsen, Michael G. Spelios, Michael S. Radin and Eitan M. Akirav Source Type: research

The impact of the metabolic phenotype on thyroid function in obesity
Obesity is known to promote mild hyperthyrotropinaemia by unknown metabolic mechanisms. This investigation aimed to explore the association between thyroid function and metabolic phenotype in euthyroid obese i... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - August 24, 2016 Category: Endocrinology Authors: Paolo Marzullo, Chiara Mele, Stefania Mai, Gabriele Guzzaloni, Davide Soranna, Maria Antonella Tagliaferri, Maria Elisa Berselli, Flavia Prodam, Daniela Surico, Gianluca Aimaretti and Massimo Scacchi Source Type: research

Use of Hba1c to Diagnose Type 2 Diabetes Mellitus among High Risk Sri Lankan Adults
Conclusion Our study showed that optimum HbA1C cut-off for detecting diabetes was 6.3% and it had better sensitivity, but lower specificity than FPG. This study further showed that the prevalence of diabetes would become double if HbA1c is used over FPG to screen this high risk population. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

Levels of physical activity are correlated with intima media ratio in subjects without but not with Metabolic Syndrome: A study of Iranians without a history of cardiovascular events
Conclusion physical activity in the current study appeared to be a correlate of infraclinical CVD risk in participants without metabolic syndrome, but not in those without. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

The Six Obesity Indices, Which One is more Compatible with metabolic syndrome? A population Based Study
Publication date: Available online 23 August 2016 Source:Diabetes & Metabolic Syndrome: Clinical Research & Reviews Author(s): Nima Motamed, Masoudreza Sohrabi, Hossein Poustchi, Mansooreh Maadi, Mojtaba Malek, Hossein Keyvani, Mahboobeh Safaean Amoli, Farhad Zamani (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

The influence of transcutaneous electrical nerve stimulation parameters on the level of pain perceived by participants with painful diabetic neuropathy: A crossover study
Conclusion Acupuncture-like TENS may be more effective for PDN than traditional TENS. A larger scale replication of this pilot study is warranted. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

Burden and risk factors of dyslipidemia-results from a STEPS survey in Punjab India
Conclusions The study reported high prevalence of dyslipidemia, calling for an urgent attention. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

Glucose variability indices predict the episodes of nocturnal hypoglycemia in elderly type 2 diabetic patients treated with insulin
Conclusion The analysis of CGM-derived GV parameters could improve prediction of NH in elderly patients with type 2 diabetes treated with insulin. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

Relationship between amputation and risk factors in individuals with diabetes mellitus: a study with brazilian patients
Conclusion The risk factors for amputation can be predicted for people with diabetes mellitus and, in the present study, the main factors were the presence of an ulcer and the smoking habit. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

Endothelial progenitor cells dysfunction and impaired tissue reparation: The missed link in diabetes mellitus development
Publication date: Available online 23 August 2016 Source:Diabetes & Metabolic Syndrome: Clinical Research & Reviews Author(s): Alexander E. Berezin Diabetes mellitus (DM) is considered a leading cause of premature cardiovascular (CV) mortality and morbidity in general population and in individuals with known CV disease. Recent animal and clinical studies have shown that reduced number and weak function of endothelial progenitor cells (EPCs) may not only indicate to higher CV risk, but contribute to the impaired heart and vessels reparation in patients with DM. Moreover, EPCs having a protective impact on t...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

Titration of basal insulin or immediate addition of rapid acting insulin in patients not at target using basal insulin supported oral antidiabetic treatment – a prospective observational study in 2,202 patients
Conclusion These findings provide evidence that treatment intensification in patients with type 2 diabetes not at glycemic target on BOT with insulin glargine is equally safe and effective using either long-acting insulin titration alone or the addition of a rapid-acting insulin analogue. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

Pancreatitis associated with antipsychotic agents
Pancreatitis is relatively uncommon but can be associated with diabetes, hyperlipidemia, and metabolic syndrome. In addition, acute pancreatitis can be caused by alcohol and some medications, including atypical antipsychotics, valproic acid, and newer anti‐diabetic agents such as GLP‐1 agonists and DDP‐IV inhibitors.1,2 (Source: The Brown University Psychopharmacology Update)
Source: The Brown University Psychopharmacology Update - August 24, 2016 Category: Psychiatry Authors: Y. W. Francis Lam Tags: Drug ‐Drug Interactions Source Type: research

IJERPH, Vol. 13, Pages 841: Association between Serum Uric Acid and Elevated Alanine Aminotransferase in the General Population
Conclusions: Our results indicated that an increased SUA level, even within the reference range, was independently associated with elevated ALT in Chinese adults. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - August 24, 2016 Category: Environmental Health Authors: Shuang Chen Xiaofan Guo Shasha Yu Guozhe Sun Hongmei Yang Zhao Li Yingxian Sun Tags: Article Source Type: research

Nonalcoholic fatty liver disease and metabolic syndrome: Shared genetic basis of pathogenesis
(Source: Hepatology)
Source: Hepatology - August 24, 2016 Category: Internal Medicine Authors: Silvia Sookoian, Carlos J. Pirola Tags: Editorial Source Type: research

New anthropometric indices or old ones: Which is the better predictor of body fat?
Conclusion All anthropometric parameters could predict body fat percent with relatively good power, however BMI, WHtR and AVI are more powerful predictors. Based on our findings, we suggest using the AVI and WHtR instead of other indexes, as they are better able to assess the accumulation of fat in the abdominal area and are able to more accurately assess body fat percent, which are indicators of chronic disease. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - August 24, 2016 Category: Endocrinology Source Type: research

High intake of regular-fat cheese compared with reduced-fat cheese does not affect LDL cholesterol or risk markers of the metabolic syndrome: a randomized controlled trial.
CONCLUSION: A high daily intake of regular-fat cheese for 12 wk did not alter LDL cholesterol or MetS risk factors differently than an equal intake of reduced-fat cheese or an isocaloric amount of carbohydrate-rich foods. This trial was registered at www.clinicaltrials.gov as NCT02616471. PMID: 27557654 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - August 24, 2016 Category: Nutrition Authors: Raziani F, Tholstrup T, Kristensen MD, Svanegaard ML, Ritz C, Astrup A, Raben A Tags: Am J Clin Nutr Source Type: research

Olive oil, compared to a saturated dietary fat, has a protective role on atherosclerosis in niacin-treated mice with metabolic syndrome
Publication date: October 2016 Source:Journal of Functional Foods, Volume 26 Author(s): Sergio Montserrat-de la Paz, Maria C. Naranjo, Sergio Lopez, Rocio Abia, Francisco J.G. Muriana, Beatriz Bermudez We aimed to investigate the impact of high-fat low-cholesterol diets rich in saturated fatty acids (HFLCD-SFAs), monounsaturated FAs (HFLCD-MUFAs) or MUFAs + omega-3 long-chain polyunsaturated FAs (HFLCD-PUFAs) in combination with niacin (NA) on atherosclerotic plaque characteristics in a mouse model (Lepob/obLDLR−/−) of metabolic syndrome (MetS). Compared to a low-fat low-cholesterol diet (LFLCD), HFLCDs increased ...
Source: Journal of Functional Foods - August 24, 2016 Category: Nutrition Source Type: research

Lower body weight and BMI at birth were associated with early adiposity rebound in 21-hydroxylase deficiency patients.
Authors: Takishima S, Nakajima K, Nomura R, Tsuji-Hosokawa A, Matsuda N, Matsubara Y, Ono M, Miyai K, Takasawa K, Morio T, Hasegawa Y, Kashimada K Abstract 21-hydroxylase deficiency (21-OHD) is the most common type of congenital adrenal hyperplasia. In addition to the clinical problems caused by adrenal insufficiency and androgen excess, a risk for obesity and metabolic syndrome during young adulthood is a major ramification of the disease. Although glucocorticoid therapy is very likely to be one of the contributory factors, the precise causes of the metabolic status of adult 21-OHD patients remain to be clarified....
Source: Endocrine Journal - August 23, 2016 Category: Endocrinology Tags: Endocr J Source Type: research

Prolonged transfer of feces from the lean mice modulates gut microbiota in obese mice
Transplanting a fecal sample from lean, healthy donors to obese recipients has been shown to improve metabolic syndrome symptoms. We therefore examined the gut microbiota in mice after administering a long-ter... (Source: Nutrition and Metabolism)
Source: Nutrition and Metabolism - August 23, 2016 Category: Nutrition Authors: Maria Kulecka, Agnieszka Paziewska, Natalia Zeber-Lubecka, Filip Ambrozkiewicz, Michal Kopczynski, Urszula Kuklinska, Kazimiera Pysniak, Marta Gajewska, Michal Mikula and Jerzy Ostrowski Source Type: research