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Total 106 results found since Jan 2013.
PIPAC versus HIPEC: cisplatin spatial distribution and diffusion in a swine model.
Conclusions: With doses used in clinical practice, HIPEC guaranteed a higher cisplatin peritoneal uptake than PIPAC in this swine model. Spatial drug distribution was heterogeneous with both technics, with hotspots closed to the drug delivery sites. Nevertheless, considering the dose ratio, IP drug uptake yield was better with PIPAC.
PMID: 32003300 [PubMed - in process]
Source: International Journal of Hyperthermia - February 1, 2020 Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
Downregulation of miR-320a/383-sponge-like long non-coding RNA NLC1-C (narcolepsy candidate-region 1 genes) is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation
Downregulation of miR-320a/383-sponge-like long non-coding RNA NLC1-C (narcolepsy candidate-region 1 genes) is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation
Cell Death and Disease 6,
e1960 (November 2015). doi:10.1038/cddis.2015.267
Authors: M Lü, H Tian, Y-x Cao, X He, L Chen, X Song, P Ping, H Huang & F Sun
Source: Cell death and disease - November 5, 2015 Category: Internal Medicine Authors: M LüH TianY-x CaoX HeL ChenX SongP PingH HuangF Sun Source Type: research
Pd13-10 preclinical trial of serial mitogel® instillations into the pelvicalyceal system of the yorkshire swine
MitoGel® is a novel drug consisting of TC-3 - a novel hydrogel polymer that is liquid at cold temperatures, but solidifies to a gel state at body temperature - and can be combined with varying doses of mitomycin C (MMC). MitoGel® has generated interest as a treatment for upper tract urothelial cancer given its ability to provide sustained contact between MMC and the urothelium of the pelvicalyceal system. The safety of repeated instillations of MitoGel® is not fully established. Herein we present preliminary results of serial instillations of MitoGel® into the kidneys of Yorkshire swine.
Source: The Journal of Urology - March 28, 2016 Category: Urology & Nephrology Authors: Nicholas Donin, Sandra Duarte, Dalit Strauss-Ayali, Yael Agmon-Gerstein, Nadav Malchi, Allan Pantuck, Arie Belldegrun, Karim Chamie Tags: Bladder Cancer: Upper Tract Transitional Cell Carcinoma I Source Type: research
Correlation of molecular and morphologic effects of thermoembolization in a swine model using mass spectrometry imaging
AbstractHepatocellular carcinoma is a growing worldwide problem with a high mortality rate. This malignancy does not respond well to chemotherapy, and most patients present late in their disease at which time surgery is no longer an option. Over the past three decades, minimally invasive methods have evolved to treat unresectable disease and prolong survival. Intra ‐arterial embolization techniques are used for large or multiple tumors but have distressingly high levels of local recurrence and can be costly to implement. A new method called thermoembolization was recently reported, which destroys target tissue by combini...
Source: Journal of Mass Spectrometry - December 4, 2019 Category: Chemistry Authors: Chunxiao Guo,
Dodge L. Baluya,
Emily A. Thompson,
Elizabeth M. Whitley,
Erik N.K. Cressman Tags: SPECIAL ISSUE ‐ RESEARCH ARTICLE Source Type: research
Abstracts of Presentations at the Association of Clinical Scientists 143 < sup > rd < /sup > Meeting Louisville, KY May 11-14,2022
Conclusion: These assays are suitable for routine diagnostic. The UltraFast NextGenPCR is the fastest with average time (30mins), followed by Agilent (2 hrs) and MassArray (6hrs). Upon completion of this activity, participants should be able to examine, measure and compare results from different assays for SARS detection, evaluate and diagnose accurately, as well as being able to plan, organize and recommend a diagnostic procedure for diagnostic laboratory. Key words: SARS-CoV-2, RNA extraction, RT-PCR, limit of detection, quantification cycle, COVID-19, in vitro diagnostic tests, Agilent, Massarray, Ultrafast. [20] From t...
Source: Annals of Clinical and Laboratory Science - July 1, 2022 Category: Laboratory Medicine Source Type: research
