Filtered By:
Condition: Obesity

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 457 results found since Jan 2013.

Treatment with sodium oxybate decreases body mass index in narcolepsy type 1
Introduction: Individuals with narcolepsy type 1 often gain body weight after disease onset, frequently leading to obesity. Previous work suggested this weight gain may be counteracted by treatment with sodium oxybate (SXB). This has not yet been confirmed, and long-term follow-up data are not available. We assessed body mass index (BMI) change after initiating treatment with SXB and compared this with BMI change after initiating treatment with modafinil in narcolepsy type 1.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: M. Schinkelshoek, I. Smolders, C. Donjacour, W. van der Meijden, E. van Zwet, R. Fronczek, G.J. Lammers Tags: Narcolepsy Source Type: research

Flu Has ‘ Definitely Peaked ’ Nationally; Remains High In Mass.
By Susan Scutti, CNN (CNN) — Flu has been shown the door in the United States. Illness activity peaked and began to decline during the eighth week of the year, the US Centers for Disease Control and Prevention’s weekly surveillance report indicated Friday. Just 5% of people who visited their doctors did so while complaining of flu-like illness, down from 6.4% the previous week. Caused by viruses, flu is a contagious respiratory illness with mild to severe symptoms that can sometimes lead to death. “We have definitely peaked,” CDC spokeswoman Kristen Nordlund said, quickly adding, “that doesn&#...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 3, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Flu Source Type: news

Medical News Today: Weight may affect the risk of flu hospitalization
Hospitalization due to flu or flu-like viruses is more likely in underweight adults or those with obesity in the morbid range or higher, says a new study.
Source: Health News from Medical News Today - December 7, 2018 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Morbidly obese should be given free flu jab, say health experts
Nearly one million morbidly obese people should be given the flu vaccine putting them in the same league as those with asthma, diabetes and heart disease
Source: Telegraph Health - March 18, 2015 Category: Consumer Health News Tags: obese morbid flu phe jab vaccine Source Type: news

Chronic pain in narcolepsy type 1 and type 2 - an underestimated reality.
The objective of the study was to determine the frequency and the characteristic of chronic pain according to the type of narcolepsy. We also investigated the effect of the interaction between the nutritional status and the type of narcolepsy. It was a cross-sectional study using self-administered questionnaires. Patients with narcolepsy (33 type 1 and 33 type 2), from Universidade Federal de São Paulo, Brazil, matched by age and gender to 33 control subjects were included. Both types of narcolepsy presented a high frequency of chronic pain (84.84% type 1 versus 75.75% type 2), with indistinct pain characteristics between...
Source: Journal of Sleep Research - June 19, 2018 Category: Sleep Medicine Authors: Cremaschi RC, Hirotsu C, Tufik S, Coelho FM Tags: J Sleep Res Source Type: research

The first influenza pandemic of the 21st century
 The 2009 H1N1 influenza virus (formerly known as swine flu) first appeared in Mexico and the United States in March and April 2009 and has swept the globe with unprecedented speed as a result of airline travel. On June 11, 2009, the World Health Organization raised its pandemic level to the highest level, Phase 6, indicating widespread community transmission on at least two continents. The 2009 H1N1 virus contains a unique combination of gene segments from human, swine and avian influenza A viruses. Children and young adults appear to be the most affected, perhaps reflecting protection in the elderly owing to exposur...
Source: Annals of Saudi Medicine - July 17, 2017 Category: General Medicine Tags: ISSUE 1 Source Type: research

Glucose and Fat Metabolism in Narcolepsy and the Effect of Sodium Oxybate: A Hyperinsulinemic-Euglycemic Clamp Study
Conclusion:We show that narcolepsy patients are more insulin sensitive and may have a lower rate of lipolysis than matched controls. SXB stimulated lipolysis in narcolepsy patients, possibly accounting for the weight loss after treatment. While sodium oxybate tended to decrease systemic insulin sensitivity, it increased hepatic insulin sensitivity, suggesting tissue-specific effects.Citation:Donjacour CE; Aziz NA; Overeem S; Kalsbeek A; Pijl H; Lammers GJ. Glucose and fat metabolism in narcolepsy and the effect of sodium oxybate: a hyperinsulinemic-euglycemic clamp study. SLEEP 2014;37(4):795-801.
Source: Sleep - April 1, 2014 Category: Sleep Medicine Source Type: research

Mortality and comorbidities in narcolepsy - an Olmsted County, Minnesota community-based study (S14.005)
Conclusions:There was a non-significant increase in age-adjusted mortality with narcolepsy. Close attention should be given to the significantly increased comorbidities of obstructive sleep apnea, low back pain, depression, anxiety, and thyroid disease.Disclosure: Dr. Cohen has nothing to disclose. Dr. Mandrekar has nothing to disclose. Dr. St. Louis has received personal compensation for activities with Axovant, Inc. and Inspire, Inc. Dr. Silber has received royalty payments from UpToDate. Dr. Kotagal has received personal compensation for activities with INC Research. Dr. Kotagal has received royalty payments from UpToDate.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Cohen, A., Mandrekar, J., St. Louis, E., Silber, M., Kotagal, S. Tags: Highlights in Sleep Science Source Type: research

Narcolepsy, Precocious Puberty and Obesity in the Pediatric Population: a Literature Review.
Authors: Maia Palhano AC, Kim LJ, Moreira GA, Santos Coelho FM, Tufik S, Levy Andersen M Abstract Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic and hypnopompic hallucinations. The onset of the symptoms usually occurs in childhood, and previous studies have reported an association between narcolepsy and other endocrine diseases in the pediatric population, such as obesity and precocious puberty. The incidence of overweight or obesity ranges from 25% to 74% in patients with narcolepsy type I, while precocious puberty is present in 17% of childr...
Source: Pediatric Endocrinology Reviews - December 18, 2018 Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research

Comorbidity and Mortality of Narcolepsy: A Controlled Retro- and Prospective National Study
Conclusions:Patients with narcolepsy present higher morbidity several years prior to diagnose and even higher thereafter. The mortality rate due to narcolepsy was slightly but not significantly higher.Citation:Jennum P; Ibsen R; Knudsen S; Kjellberg J. Comorbidity and mortality of narcolepsy: a controlled retro- and prospective national study. SLEEP 2013;36(6):835-840.
Source: Sleep - May 31, 2013 Category: Sleep Medicine Source Type: research

Health-related quality of life in patients with narcolepsy types 1 and 2 from a Sleep Center in Brazil
Conclusion: In a Sleep Center in S ão Paulo, Brazil, physical and mental health were impaired in narcolepsy types 1 and 2. The first report of the poor health status in Brazilians with narcolepsy type 2 suggests that obesity negatively affects physical domains.RESUMO Introdu ção: Pacientes com narcolepsia têm maior prevalência de comorbidades, como obesidade, depressão e dor. Sintomas de narcolepsia e condições médicas concomitantes podem afetar as atividades diárias dos pacientes. O objetivo deste estudo é escrever a qualidade de vida em uma amostra de pacie ntes com narcolepsia e a influência do estado nutric...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Energy Expenditure in Narcolepsy Patients and Controls (P5.292)
ConclusionEnergy expenditure in narcolepsy patients is similar to matched controls. It is conceivable that we were not close enough to onset of the disease, when patients usually gain weight, to detect a possible difference before a new metabolic set point establishes.Study Supported by:UCB PharmaDisclosure: Dr. Donjacour has nothing to disclose. Dr. Schoffelen has nothing to disclose. Dr. Overeem has received personal compensation for activities with UCB Pharma, Novartis, and Boehringer Ingelheim Pharmaceuticals Inc. Dr. Overeem has received research support from UCB Pharma. Dr. Lammers has received personal compensation ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Donjacour, C., Schoffelen, P., Overeem, S., Lammers, G. J., Pijl, H., Westerterp, K. Tags: Sleep: Intrinsic Disorders of Sleep Source Type: research

Demographic and Clinical Correlates of Narcolepsy in Adolescents Hospitalized with Mood Disorders: A Nationwide Inpatient Sample (NIS) Study
CONCLUSIONS: Our study results suggest a significantly higher prevalence of obesity and sleep apnea comorbidity in mood-disordered adolescents with narcolepsy with an overall negative impact on hospital outcomes.PMID:35833841 | DOI:10.1080/15402002.2022.2099862
Source: Behavioral Sleep Medicine - July 14, 2022 Category: Sleep Medicine Authors: Rikinkumar S Patel Nikhila Veluri Amit Chopra Source Type: research