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Condition: Anorexia

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Total 588 results found since Jan 2013.

Control of a Reassortant Pandemic 2009 H1N1 Influenza Virus Outbreak in an Intensive Swine Breeding Farm: Effect of Vaccination and Enhanced Farm Management Practices
Conclusions Although our study design was sub-optimal for evaluating the effectiveness of the intervention, we provided suggestive evidence that H1N1pdm-targeted vaccination in sows/gilts, enhanced biosecurity, lengthening of weaning cycles, and constrains in cross-fostering of piglets may prove useful in controlling a reassortant H1N1pdm outbreak in an intensive swine breeding farm without possibility of applying an all-in/all-out system. Maternally-derived immunity was elicited and further virus circulation in piglets dropped to undetectable levels, while keeping farm productivity at full. The present field study also su...
Source: PLOS Currents Outbreaks - April 13, 2015 Category: Epidemiology Authors: Lapo Mughini-Gras Source Type: research

Stage of Gestation at Porcine Epidemic Diarrhea Virus Infection of Pregnant Swine Impacts Maternal Immunity and Lactogenic Immune Protection of Neonatal Suckling Piglets
In this study, we infected pregnant first parity gilts in their first, second and third trimesters of gestation with PEDV to determine the impact of stage of gestation on generation of maternal B-cell immunity, the gut-MG-sIgA axis and lactogenic immune protection in PEDV challenged piglets. Our goal was to identify innate and adaptive immune factors during pregnancy that influence lymphocyte trafficking, in addition to immune correlates of lactogenic immune protection in neonatal suckling piglets. Understanding the impact of stage of gestation at PEDV infection or exposure on maternal immunity will allow more precise mate...
Source: Frontiers in Immunology - April 23, 2019 Category: Allergy & Immunology Source Type: research

Pathogenesis and vaccination of influenza a virus in Swine.
Authors: Rajao DS, Anderson TK, Gauger PC, Vincent AL Abstract Swine influenza is an acute respiratory disease of pigs caused by influenza A virus (IAV) and characterized by fever followed by lethargy, anorexia, and serous nasal discharge. The disease progresses rapidly and may be complicated when associated with other respiratory pathogens. IAV is one of the most prevalent respiratory pathogens of swine, resulting in substantial economic burden to pork producers. In the past 10-15 years, a dramatic evolution of the IAV in U.S. swine has occurred, resulting in the co-circulation of many antigenically distinct IAV ...
Source: Current Topics in Microbiology and Immunology - November 12, 2014 Category: Microbiology Tags: Curr Top Microbiol Immunol Source Type: research

Systematic Epidemiological Investigations of Cases of Senecavirus A in US Swine Breeding Herds
Summary Epidemiological investigations were conducted on a case series of six Senecavirus A (SVA)‐affected breeding herds in the United States to determine potential routes of introduction and enhance the swine industry's knowledge of SVA's clinical presentation and spread. Each SVA‐affected herd was evaluated using a standard form to ensure that all relevant data were collected. The form was used to guide a detailed discussion about the clinical presentation of SVA and risk events that occurred in the 4 weeks prior to the first observation of clinical signs with the herd veterinarian and farm personnel. Each event wa...
Source: Transboundary and Emerging Diseases - November 24, 2016 Category: Veterinary Research Authors: K. L. Baker, C. Mowrer, A. Canon, D. C. L. Linhares, C. Rademacher, L. A. Karriker, D. J. Holtkamp Tags: Rapid Communication Source Type: research

Variations in clinical presentation and anatomical distribution of gross lesions of African swine fever in domestic pigs in the southern highlands of Tanzania: a field experience
AbstractAfrican swine fever is a contagious viral disease responsible for up to 100% mortality among domestic pigs. A longitudinal study was carried out to determine the clinical presentation and anatomical distribution of gross lesions in affected pigs in Mbeya region, Tanzania during the 2010 to 2014 outbreaks. Data were collected during clinical and postmortem examination by field veterinarians and using a structured questionnaire. A total of 118 respondents (100%) showed awareness about African swine fever. During previous outbreaks, the mortality rate was almost 100%, while in 2014 it was estimated to be less than 50%...
Source: Tropical Animal Health and Production - December 2, 2016 Category: Veterinary Research Source Type: research

Viruses, Vol. 15, Pages 858: Comparison of Genotype II African Swine Fever Virus Strain SY18 Challenge Models
Min Li Rongliang Hu African swine fever (ASF) is a viral haemorrhagic disease found in domestic and wild boars caused by the African swine fever virus (ASFV). A highly virulent strain was used to evaluate the efficacy of newly developed vaccine candidates. The ASFV strain SY18 was isolated from the first ASF case in China and is virulent in pigs of all ages. To evaluate the pathogenesis of ASFV SY18 following intraoral (IO) and intranasal (IN) infections, a challenge trial was conducted in landrace pigs, with intramuscular (IM) injection as a control. The results showed that the incubation period of IN administration...
Source: Viruses - March 27, 2023 Category: Virology Authors: Xintao Zhou Jiaqi Fan Xiaopan Guo Teng Chen Jinjin Yang Yanyan Zhang Lijuan Mi Fei Zhang Faming Miao Min Li Rongliang Hu Tags: Article Source Type: research

Pathogenesis of highly pathogenic porcine reproductive and respiratory syndrome virus in Chinese Tibetan swine
In this study, 15 4-week-old Tibetan piglets were divided into three groups, and their susceptibility to HP-PRRSV was examined in the highland region. Five pigs in group 1 were inoculated intranasally with HP-PRRSV strain BB0907. At 2 days post-inoculation, five other pigs were introduced into this group and then removed to a separated room to serve as contact group 2. Meanwhile, five pigs in group 3 were mock infected and used as controls. The results showed that the pigs in the inoculated and contact groups showed high fevers and clear clinical signs, including depression, anorexia, lethargy, sticky eye secretions, and h...
Source: Research in Veterinary Science - July 29, 2016 Category: Veterinary Research Source Type: research

GSE111378 Comparison of the transcriptome response within the tracheobronchial lymph node following infection with Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus 2 or Swine Influenza A Virus.
Contributors : Laura C Miller ; Damarius S Fleming ; Gregory P Harhay ; Marcus E Kehrli ; Kelly M LagerSeries Type : Expression profiling by high throughput sequencingOrganism : Sus scrofa domesticusThe aim of this study was to acquire a better understanding of porcine reproductive and respiratory syndrome (PRRS) disease through a deeper knowledge of gene expression changes that occur in pulmonary lymph nodes by comparing PRRS virus (PRRSV), porcine circovirus type 2 (PCV-2), and swine influenza virus (IAV-S) infections. The PRRSV, IAV-S and PCV-2 viral infections followed a clinical course in these domestic pigs typi...
Source: GEO: Gene Expression Omnibus - March 3, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Sus scrofa domesticus Source Type: research

Virulence evaluation of classical swine fever virus subgenotype 2.1 and 2.2 isolates circulating in China
Publication date: Available online 3 April 2019Source: Veterinary MicrobiologyAuthor(s): Wenjie Gong, Junhui Li, Zunbao Wang, Jiumeng Sun, Shijiang Mi, Zongji Lu, Jian Cao, Zhihua Dou, Yanjun Sun, Pengjiang Wang, Ke Yuan, Liying Zhang, Xubin Zhou, Sun He, Changchun TuAbstractClassical swine fever (CSF) remains an important pig disease in China, where it usually presents with mild or atypical clinical manifestations, with large scale outbreaks rarely seen. This has led to speculation about the possible circulation of viral strains of low virulence. To investigate this possibility, five field isolates within the predominant ...
Source: Veterinary Microbiology - April 4, 2019 Category: Veterinary Research Source Type: research

Toward better control of classical swine fever in wild boars: susceptibility of boar-pig hybrids to a recent Japanese isolate and effectiveness of a bait vaccine
AbstractWe analyzed the pathogenicity of a recent Japanese classical swine fever virus (CSFV) to wild boars via an experimental infection using boar-pig hybrids as an alternative to wild boars. We also investigated the effectiveness of a bait vaccine against the CSFV. Na ïve boar-pig hybrids and pigs showed clinical signs such as fever, leucopenia, anorexia and conjunctivitis following the experimental infection. In contrast, the boar-pig hybrids administered the bait vaccine did not show any clinical signs. Our data indicated that boar-pig hybrids and domestic pig s have similar susceptibility to the recent Japanese CSFV...
Source: Veterinary Research - July 30, 2020 Category: Veterinary Research Source Type: research

Large animals as potential models of human mental and behavioral disorders.
Authors: Danek M, Danek J, Araszkiewicz A Abstract Many animal models in different species have been developed for mental and behavioral disorders. This review presents large animals (dog, ovine, swine, horse) as potential models of this disorders. The article was based on the researches that were published in the peer-reviewed journals. Aliterature research was carried out using the PubMed database. The above issues were discussed in the several problem groups in accordance with the WHO International Statistical Classification of Diseases and Related Health Problems 10thRevision (ICD-10), in particular regarding: ...
Source: Psychiatria Polska - February 14, 2018 Category: Psychiatry Tags: Psychiatr Pol Source Type: research

Artist Illustrates The Realities Of Mental Health, From A(nxiety) To Z
"I'm doing everything wrong." "Everyone's laughing at me." "I think I left the door open." Anxiety comes in different shapes and sizes. #atozofmentalhealth - - - - - #365daysofart #drawingaday #36daysoftype @36daysoftype #36days_A #36daysoftype04 #mentalhealth #art #typography #lettering #colors #anxiety #watercolor #igart #sketchbook #digitalart #illustration #selflove #care #mentalhealthawareness #endthestigma A post shared by Sonaksha Iyengar (@sonaksha) on Feb 21, 2017 at 8:22am PST A is for anxiety, which itself comes in many shapes and colors. B is for bipolar disorder, a term...
Source: Healthy Living - The Huffington Post - March 7, 2017 Category: Consumer Health News Source Type: news

A multicenter, single-arm, Phase II clinical trial of bendamustine monotherapy in patients with chronic lymphocytic leukemia in Japan.
Abstract The present study was intended to examine the efficacy and safety of bendamustine monotherapy in patients with previously untreated chronic lymphocytic leukemia (CLL) for whom treatment with fludarabine (FLU) was not suitable, and in FLU-naïve patients with relapsed/refractory CLL. We intravenously administered bendamustine 100 mg/m(2)/day on days 1 and 2 of each 28-day cycle to 10 patients (eight previously untreated; two relapsed/refractory) up to six cycles. The primary endpoint was overall response rate (ORR: partial remission or better) according to the 2008 International Workshop on the CLL guidel...
Source: International Journal of Hematology - February 2, 2017 Category: Hematology Authors: Ogawa Y, Izutsu K, Kiguchi T, Choi I, Takatsuka Y, Ando K, Suzumiya J, Japanese Bendamustine CLL Study Group Tags: Int J Hematol Source Type: research

Mazindol: a risk factor for pulmonary arterial hypertension?
Mazindol is an imidazo-isoindole derivative, tricyclic compound and a non-amphetamine central nervous system stimulant that blocks dopamine and norepinephrine reuptake. Mazindol was withdrawn from the US and European markets in 1999 for reasons unrelated to efficacy or safety around a time when other anorexic drugs were concluded to be associated with the development of pulmonary arterial hypertension (PAH). Despite decades of use, reports of PAH with mazindol have been extremely rare. Recent interest has emerged for mazindol for the treatment of narcolepsy and attention deficit hyperactivity disorder (ADHD).
Source: Sleep Medicine - March 17, 2017 Category: Sleep Medicine Authors: Eric Konofal, Cherine Benzouid, Christophe Delclaux, Michel Lecendreux, Elizabeth Hussey Tags: Brief Communication Source Type: research

Brief history of the medical and non-medical use of amphetamine-like psychostimulants
Exp Neurol. 2021 May 14:113754. doi: 10.1016/j.expneurol.2021.113754. Online ahead of print.ABSTRACTThe alkaloid ephedrine derived from Ephedra vulgaris is at the origin of psychostimulant-drugs as amphetamine. These drugs have been principally utilized for medical treatments in the past, while their utilization has been largely reduced from the 1970s when the high risk of addiction and abuse has been recognized. The first reported treatments were as anti-asthmatics and to contrast narcolepsy until their recreational stimulant and anorexic effects were reported. Benzedrine and Pervitin use were of great importance during t...
Source: Experimental Neurology - May 17, 2021 Category: Neurology Authors: Micaela Morelli Eugenia Tognotti Source Type: research