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From bad to worse: How avian flu must change to trigger a human pandemic
The victims are varied, from thousands of sea lions off the coast of Peru to mink farmed for fur in Spain to grizzly bears in Montana and harbor seals in Maine. For months, the avian influenza virus that has been
decimating birds across the world
has also sickened and killed a menagerie of mammals, raising fears it might evolve to spread more efficiently between these animals, and ultimately between people.
For that nightmare to unfold, however, the virus, a subtype known as H5N1, would have to undergo a major transformation, changing from a pathogen efficient at infecting cells in the guts of birds and spreadin...
Source: ScienceNOW - April 6, 2023 Category: Science Source Type: news
Narcolepsy and adjuvanted pandemic influenza A (H1N1) 2009 vaccines - Multi-country assessment.
CONCLUSIONS: Other than elevated narcolepsy IRs in the period after vaccination campaigns in Sweden, we did not find an association between AS03- or MF59-adjuvanted pH1N1 vaccines and narcolepsy in children or adults in the sites studied, although power to evaluate the AS03-adjuvanted Pandemrix brand vaccine was limited in our study.
PMID: 30122647 [PubMed - as supplied by publisher]
Source: Vaccine - August 16, 2018 Category: Allergy & Immunology Authors: Weibel D, Sturkenboom M, Black S, de Ridder M, Dodd C, Bonhoeffer J, Vanrolleghem A, van der Maas N, Lammers GJ, Overeem S, Gentile A, Giglio N, Castellano V, Kwong JC, Murray BJ, Cauch-Dudek K, Juhasz D, Campitelli M, Datta AN, Kallweit U, Huang WT, Huan Tags: Vaccine Source Type: research
Change in brain cells linked to opiate addiction, narcolepsy
This study was supported by grants from the National Institute on Drug Abuse and the Medical Research Service of the U.S. Department of Veterans Affairs.
Source: UCLA Newsroom: Health Sciences - June 27, 2018 Category: Universities & Medical Training Source Type: news
Infection by Brazilian and Dutch swine hepatitis E virus strains induces haematological changes in Macaca fascicularis
Conclusions:
The ability of HEV to cross the species barrier was confirmed for both the swine (Brazilian and Dutch) and human (Argentinean) strains, thus reinforcing the zoonotic risk of hepatitis E in South America. Cynomolgus monkeys that were infected with HEV genotype 3 developed subclinical hepatitis that was associated with haematological changes. Haematological approaches should be considered in future studies of HEV infection.
Source: BMC Infectious Diseases - October 23, 2013 Category: Infectious Diseases Authors: Lilian de CarvalhoRenato MarchevskyDebora dos SantosJaqueline de OliveiraVanessa de PaulaLeilane LopesWilhelmus Van der PoelJorge GonzálezMaria MunnéJulio MoranAna CajaravilleMarcelo Pelajo-MachadoOswaldo CruzMarcelo Pinto Source Type: research
Keep The Flu Away In A Time Of “ Twindemics ”
Flu season is here, and the CDC has shifted into overdrive…pushing you to get your flu vaccine as soon as possible.
Once again, they’re insisting it’s more important than ever because of Covid.
Flu shots have an unquestioned reputation. The message from the medical establishment is that you need to ignore any vaccines’ potential adverse effects.
But that doesn’t mean they don’t exist…
In a moment, I’ll show you ways to bolster your native immunity so you can enjoy optimal health year-round. But first, for my new readers, let me tell you why I’ll never get a flu shot.
Unlike some of my colleagues i...
Source: Al Sears, MD Natural Remedies - December 23, 2022 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Source Type: news
IJERPH, Vol. 20, Pages 5175: School Problems and School Support for Children with Narcolepsy: Parent, Teacher, and Child Reports
Conclusions: Children with NT1 have various problems at school, even after medical treatment. Interventions to help children with NT1 within the classroom do not seem to be fully implemented. School support was associated with the higher implementation of these interventions. Longitudinal studies are warranted to examine how interventions can be better implemented within the school.
Source: International Journal of Environmental Research and Public Health - March 15, 2023 Category: Environmental Health Authors: Karin Janssens Pauline Amesz Yvonne Nuvelstijn Claire Donjacour Danielle Hendriks Els Peeters Laury Quaedackers Nele Vandenbussche Sigrid Pillen Gert Jan Lammers Tags: Article Source Type: research
Immunogenicity, Safety, and Efficacy of a Standalone Universal Influenza Vaccine, FLU-v, in Healthy Adults: A Randomized Clinical Trial.
Conclusion: Adjuvanted FLU-v is immunogenic and merits phase 3 development to explore efficacy.
Primary Funding Source: SEEK and the European Commission Directorate-General for Research and Innovation, European Member States within the UNISEC (Universal Influenza Vaccines Secured) project.
PMID: 32150750 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - March 9, 2020 Category: Internal Medicine Authors: Pleguezuelos O, Dille J, de Groen S, Oftung F, Niesters HGM, Islam MA, Næss LM, Hungnes O, Aldarij N, Idema DL, Perez AF, James E, Frijlink HW, Stoloff G, Groeneveld P, Hak E Tags: Ann Intern Med Source Type: research
Human Infection with Eurasian Avian-Like Swine Influenza A(H1N1) Virus, the Netherlands, September 2019
We report a zoonotic infection of a pig farmer in the Netherlands with a Eurasian avian-like swine influenza A(H1N1) virus that was also detected in the farmed pigs. Both viruses were antigenically and genetically characterized. Continued surveillance of swine influenza A viruses is needed for risk assessment in humans and swine.PMID:33622472 | DOI:10.3201/eid2703.201863
Source: Emerging Infectious Diseases - February 24, 2021 Category: Infectious Diseases Authors: Anna Parys Elien Vandoorn Jacqueline King Annika Graaf Anne Pohlmann Martin Beer Timm Harder Kristien Van Reeth Source Type: research
Dutch Authorities Identify Highly Contagious Bird Flu Strain
By Thomas Escritt
AMSTERDAM, Nov 16 (Reuters) - Dutch authorities said on Sunday they had found a highly contagious strain of bird flu at a poultry farm in the central Netherlands and set about destroying 150,000 chickens.
The strain, H5N8, has never been detected in humans, but an outbreak in South Korea meant millions of farm birds had to be slaughtered to contain the outbreak. Cases have also been reported in China and Japan, although the strain was first reported in Europe, on a German farm, in early November.
The Netherlands imposed a 72-hour ban on transportation of poultry products, including birds, eggs, dung an...
Source: Healthy Living - The Huffington Post - November 16, 2014 Category: Consumer Health News Source Type: news
Appearance of reassortant European avian ‐origin H1 influenza A viruses of swine in Vietnam
Summary
Three subtypes—H1N1, H1N2 and H3N2—of influenza A viruses of swine (IAVs‐S) are currently endemic in swine worldwide, but there is considerable genotypic diversity among each subtype and limited geographical distribution. Through IAVs‐S monitoring in Vietnam, two H1N2 influenza A viruses were isolated from healthy pigs in Ba Ria‐Vung Tau Province, Southern Vietnam, on 2 December 2016. BLAST and phylogenetic analyses revealed that their HA and NA genes were derived from those of European avian‐like H1N2 IAVs‐S that contained avian‐origin H1 and human‐like N2 genes, and were particularly closely rel...
Source: Transboundary and Emerging Diseases - March 7, 2018 Category: Veterinary Research Authors: N. Takemae, P. T. Nguyen, V. T. Le, T. N. Nguyen, T. L. To, T. D. Nguyen, V. P. Pham, H. V. Vo, Q. V. T. Le, H. T. Do, D. T. Nguyen, Y. Uchida, T. Saito Tags: SHORT COMMUNICATION Source Type: research
Simulation of transmission and persistence of African swine fever in wild boar in Denmark
Publication date: Available online 1 April 2019Source: Preventive Veterinary MedicineAuthor(s): Tariq Halasa, Anette Boklund, Anette Bøtner, Sten Mortensen, Lene Jung KjærAbstractAfrican swine fever (ASF) is caused by ASF virus (ASFV) and is currently circulating in the eastern part of Europe posing a serious risk regarding transmission to western European countries. Wild boar is a main driver of the transmission and persistence of ASFV in the endemic infected countries in Europe. Some European countries free from ASF, such as Denmark and the Netherlands, have limited population sizes of wild boar, but have large swine p...
Source: Preventive Veterinary Medicine - April 2, 2019 Category: Veterinary Research Source Type: research
