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Drug: Tetracycline

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Total 211 results found since Jan 2013.

MRSA in swine, farmers and abattoir workers in Southern Italy.
In this study, MRSA strains were isolated from 55 of the 85 (64.7%) intensive pig farms surveyed, and prevalence was greater on pig fattening farms than on breeding farms. In addition, we included in the study 63 foreign pigs imported for slaughter. Overall, the prevalence of MRSA in the 418 sampled swine was 59.1%; 12 genotypes were identified among the isolates; ST398 (96.4%) was most prevalent, followed by ST97 (2%), ST9 (0.8%) and ST1 (0.8%). MRSA isolates were also detected in 26 (17.3%) of the 150 operators included in the study; the genotypes detected were ST398 (85%), ST9 (7.6%), ST5 (3.8%) and ST1 (3.8%). All the ...
Source: Food Microbiology - April 29, 2019 Category: Food Science Authors: Parisi A, Caruso M, Normanno G, Latorre L, Miccolupo A, Fraccalvieri R, Intini F, Manginelli T, Santagada G Tags: Food Microbiol Source Type: research

Environmental fate of tetracycline resistance genes originating from swine feedlots in river water.
In this study, farming wastewater from one Chinese swine farm as well as river water from seven locations downstream of the farm was sampled. Polymerase chain reaction (PCR) showed that 12 TRGs, including six efflux pump genes (tet(B), tet(C), tet(D), tet(E), tet(G) and tet(L)), five ribosomal protection proteins (RPPs) genes (tet(O), tet(M), tet(Q), tet(W) and tet(S)), and one enzymatic modification gene (tet(X)), were present in all wastewater and river water samples. Quantitative real-time PCR (qPCR) showed that the abundance of tet(C), tet(X), tet(O), tet(M), tet(Q) and tet(W) decreased with downstream flow. Among the ...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - June 9, 2014 Category: Environmental Health Authors: Jia S, He X, Bu Y, Shi P, Miao Y, Zhou H, Shan Z, Zhang XX Tags: J Environ Sci Health B Source Type: research

Distribution of Salmonella Serovars and Antimicrobial Susceptibility from Poultry and Swine Farms in Central Vietnam
This study was conducted to estimate the prevalence of Salmonella spp. and their antimicrobial susceptibilities on poultry and swine farms, sampled in 2 regions in Central Vietnam. A total of 67 poultry farms and 46 swine farms were sampled in a period of 5 months (from September 2012 to January 2013). Salmonella spp. was prevalent in 46.3% and 71.7% of poultry and swine farms, respectively. Altogether, 99 non‐typhoidal Salmonella were isolated and the most common serovars were Salmonella Weltevreden (19%), followed by Salmonella Typhimurium (12%) and Salmonella 4,[5],12:i:‐ (11%). Overall, 71 of 99 (72%) Salmonella i...
Source: Zoonoses and Public Health - March 1, 2016 Category: Infectious Diseases Authors: A. A. Lettini, T. Vo Than, E. Marafin, A. Longo, K. Antonello, P. Zavagnin, L. Barco, M. Mancin, V. Cibin, M. Morini, M. Dang Thi Sao, T. Nguyen Thi, H. Pham Trung, L. Le, T. Nguyen Duc, A. Ricci Tags: Original Article Source Type: research

Migration and degradation of swine farm tetracyclines at the river catchment scale: Can the multi-pond system mitigate pollution risk to receiving rivers?
Abstract The study investigated the degradation behaviors of swine farm tetracyclines (TCs) at a catchment scale and explored whether multi-pond systems could be beneficial to the interception of TCs so as to reduce the pollution risk to receiving rivers. The occurrence and migration of 12 kinds of tetracycline antibiotics, including their degradation products, were studied in four swine farms of the Meijiang River basin in China. The migration paths of the TCs were examined through sampling and analyzing the soil and/or sediment at different points along the swine wastewater outlet, which included sewer, sewage p...
Source: Environmental Pollution - November 9, 2016 Category: Environmental Health Authors: Chen Q, Guo X, Hua G, Li G, Feng R, Liu X Tags: Environ Pollut Source Type: research

Occurrence of Veterinary Antibiotics in Swine Manure from Large-scale Feedlots in Zhejiang Province, China.
Abstract The occurrence and distribution of five sulfonamides and three tetracyclines in swine manure sampled from large-scale feedlots in different areas of Zhejiang Province, China were detected using solid-phase extraction and high-performance liquid chromatography. All eight test antibiotics were detected in most of the manure samples. The dominant antibiotics in swine manure were sulfadiazine, sulfamerazine, sulfadimidine, tetracycline, and chlortetracycline. The maximum concentration of residual antibiotic reached up to 57.95 mg/kg (chlortetracycline). The concentrations and distribution of both types of an...
Source: Bulletin of Environmental Contamination and Toxicology - February 26, 2017 Category: Environmental Health Authors: Wang H, Chu Y, Fang C Tags: Bull Environ Contam Toxicol Source Type: research

Tracking antibiotic resistance gene transfer at all seasons from swine waste to receiving environments
Ecotoxicol Environ Saf. 2021 May 18;219:112335. doi: 10.1016/j.ecoenv.2021.112335. Online ahead of print.ABSTRACTAntibiotic resistance genes (ARGs) in livestock farms have attracted a growing attention with potential effects on human health. As one of the most important organic fertilizer, swine waste provided an ideal environment for understanding the dissemination and accumulation of ARGs in agricultural ecosystems. Here we conducted a year-round follow-up trace from swine waste to receiving environments, with the purpose of revealing the contamination profiles and ecological risks of ARGs at different seasons. Results i...
Source: Ecotoxicology and Environmental Safety - May 21, 2021 Category: Environmental Health Authors: Bingjun Han Fengxia Yang Xueli Tian Meirui Mu Keqiang Zhang Source Type: research

Effects of subtherapeutic concentrations of antimicrobials on gene acquisition events in Yersinia, Proteus, Shigella, and Salmonella recipient organisms in isolated ligated intestinal loops of swine.
Conclusions and Clinical Relevance-10 of 16 antimicrobials at subinhibitory or subtherapeutic concentrations augmented specific antimicrobial resistance or transfer of virulence genes into pathogenic bacteria in isolated intestinal loops in swine. Use of subtherapeutic antimicrobials in animal feed may be associated with unwanted collateral effects. PMID: 23879845 [PubMed - in process]
Source: American Journal of Veterinary Research - July 27, 2013 Category: Veterinary Research Authors: Brewer MT, Xiong N, Anderson KL, Carlson SA Tags: Am J Vet Res Source Type: research

Biodegradation of three tetracyclines in swine wastewater.
In this study, we investigated the biodegradation of three TCs in swine wastewater. In batch experiments, OTC and CTC were completely degraded at d 18 and 20, respectively, but TC was remained at 7.1% after 20 d incubation. The degradation rates of TCs in the wastewater were in the order of OTC > CTC > TC. Degradation of the TCs was enhanced by the addition of enzyme extract from spent mushroom compost (SMC) of Pleurotus eryngii. The degradation rates were higher with the addition of extract-containing microcapsules than suspended enzyme extract in swine wastewater. In the bioreactor experiment, the addition of extra...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 29, 2014 Category: Environmental Health Authors: Chang BV, Hsu FY, Liao HY Tags: J Environ Sci Health B Source Type: research

Sorption of tetracycline on H3PO4 modified biochar derived from rice straw and swine manure.
Abstract Currently, the information about the sorption of tetracycline (TC) on animal manure derived biochar was rare although plant residue derived biochar showed high sorption of TC). Therefore, this study explored the sorption of TC on swine manure derived biochar, and compared with rice straw derived biochar simultaneously. Also, H3PO4 was adopted to modify both types of biochar. The sorption kinetic and isotherm data showed H3PO4 modification enhanced the sorption of TC on both types of biochar (especially swine-manure-biochar), and indicated the chemisorptions including H-bonding and π-π electron donor acc...
Source: Bioresource Technology - July 19, 2018 Category: Biotechnology Authors: Chen T, Luo L, Deng S, Shi G, Zhang S, Zhang Y, Deng O, Wang L, Zhang J, Wei L Tags: Bioresour Technol Source Type: research

Interaction of swine organic anion transporting polypeptide 1a2 with tetracycline, macrolide and β-lactam antibiotics.
Abstract Organic anion-transporting polypeptides (human OATPs; animals Oatps; gene symbol SLCO/Slco) are integral membrane proteins that mediate the sodium-independent transport of a wide range of endogenous compounds as well as many xenobiotics. Antibiotics, antidiabetic drugs, anti-inflammatory drugs, antifungals, antivirals, antihistamines, antihypertensives, fibrates, statins, cardiac glycosides, immunosuppressants, and anticancer drugs are among the substrates transported by OATPs. Because of the broad substrate specificity, wide tissue distribution and the involvement of drug-drug interaction, human OATPs ha...
Source: Toxicology and Applied Pharmacology - July 5, 2019 Category: Toxicology Authors: Lin X, Xiang Z, Wang B, Chen H, Zhou T, Hong M Tags: Toxicol Appl Pharmacol Source Type: research

Surveillance of antimicrobial resistance in clinical isolates of Pasteurella multocida and Streptococcus suis from Ontario swine.
Abstract Susceptibility results for Pasteurella multocida and Streptococcus suis isolated from swine clinical samples were obtained from January 1998 to October 2010 from the Animal Health Laboratory at the University of Guelph, Guelph, Ontario, and used to describe variation in antimicrobial resistance (AMR) to 4 drugs of importance in the Ontario swine industry: ampicillin, tetracycline, tiamulin, and trimethoprim-sulfamethoxazole. Four temporal data-analysis options were used: visualization of trends in 12-month rolling averages, logistic-regression modeling, temporal-scan statistics, and a scan with the "What'...
Source: Canadian Journal of Veterinary Research - October 1, 2014 Category: Veterinary Research Authors: Glass-Kaastra SK, Pearl DL, Reid-Smith RJ, McEwen B, Slavic D, Fairles J, McEwen SA Tags: Can J Vet Res Source Type: research

Tissue concentrations of sulfamethazine and tetracycline hydrochloride of swine (Sus scrofa domestica) as it relates to withdrawal methods for international export.
In conclusion, the TLM may not always provide adequate WDT for foreign export markets especially when MRLs differ from tolerance levels approved for US markets. However, PopPK methods can provide conservative WDIs in situations with considerable variability in medication exposure such as with administration in water. PMID: 25707857 [PubMed - as supplied by publisher]
Source: Regulatory Toxicology and Pharmacology : RTP - February 20, 2015 Category: Toxicology Authors: Mason SE, Wu H, Yeatts JE, Baynes RE Tags: Regul Toxicol Pharmacol Source Type: research

Swine Farming Is a Risk Factor for Infection With and High Prevalence of Carriage of Multidrug-Resistant Staphylococcus aureus
Conclusions. Current swine workers are 6 times more likely to carry MDRSA than those without current swine exposure. We observed active infections caused by LA-SA. This finding suggests that individuals with livestock contact may have a high prevalence of exposure to, and potentially infection with, antibiotic-resistant S. aureus strains, including LA-SA strains.
Source: Clinical Infectious Diseases - June 11, 2015 Category: Infectious Diseases Authors: Wardyn, S. E., Forshey, B. M., Farina, S. A., Kates, A. E., Nair, R., Quick, M. K., Wu, J. Y., Hanson, B. M., O'Malley, S. M., Shows, H. W., Heywood, E. M., Beane-Freeman, L. E., Lynch, C. F., Carrel, M., Smith, T. C. Tags: ARTICLES AND COMMENTARIES Source Type: research

Seasonal variation and removal efficiency of antibiotic resistance genes during wastewater treatment of swine farms.
Abstract The seasonal variation and removal efficiency of antibiotic resistance genes (ARGs), including tetracycline resistance genes (tetG, tetM, and tetX) and macrolide (ermB, ermF, ereA, and mefA), were investigated in two typical swine wastewater treatment systems in both winter and summer. ARGs, class 1 integron gene, and 16S rRNA gene were quantified using real-time polymerase chain reaction assays. There was a 0.31-3.52 log variation in ARGs in raw swine wastewater, and the abundance of ARGs in winter was higher than in summer. tetM, tetX, ermB, ermF, and mefA were highly abundant. The abundance of ARGs was...
Source: Environmental Science and Pollution Research International - December 29, 2015 Category: Environmental Health Authors: Sui Q, Zhang J, Tong J, Chen M, Wei Y Tags: Environ Sci Pollut Res Int Source Type: research