Filtered By:
Procedure: Anesthesia

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 469 results found since Jan 2013.

Management of narcolepsy during pregnancy
Conclusions: The findings from our survey and literature review suggest that the perceived risks of narcolepsy medication during pregnancy to the mother and the fetus usually are overestimated, as the risk for teratogenic effects from narcolepsy medications in therapeutic doses is essentially nonexistent. However, the potential for rare complications during pregnancy and congenital abnormalities cannot be excluded. Most narcolepsy patients have vaginal delivery without complications. In rare cases patients had cataplexy that interfered with delivery, but if caesarian is required there appears to be no increased anaesthetic...
Source: Sleep Medicine - February 25, 2013 Category: Sleep Medicine Authors: Michael Thorpy, Chi George Zhao, Yves Dauvilliers Tags: Special Section in Sleep Medicine Source Type: research

Anesthetic Management of Narcolepsy Patients During Surgery: A Systematic Review.
CONCLUSIONS: We found a paucity of prospective clinical trials in this patient population, as most of the studies were case reports or observational studies. Continuation of preoperative medications, depth of anesthesia monitoring, use of multimodal analgesia with short-acting agents and regional anesthesia techniques were associated with favorable outcomes. Obstetric patients may be at greater risk for worsening narcolepsy symptoms, possibly related to a reduction or discontinuation of medications. For neurosurgical procedures involving the hypothalamus or third and fourth ventricle, postoperative considerations should in...
Source: Anesthesia and Analgesia - December 21, 2017 Category: Anesthesiology Authors: Hu S, Singh M, Wong J, Auckley D, Hershner S, Kakkar R, Thorpy MJ, Chung F Tags: Anesth Analg Source Type: research

Narcolepsy, Anesthesia, and Sedation: A Survey of the Perioperative Experience of Patients With Narcolepsy.
CONCLUSIONS: Most narcoleptic patients report not receiving counseling regarding potential worsening of narcolepsy symptoms postanesthesia or an increased risk of drowsy driving. Enhanced education of perioperative providers about potential narcolepsy-related issues is essential. Respondents frequently self-report adverse events in the perioperative period. Future studies should clarify the perioperative risk associated with narcolepsy to optimize the care and safety of narcoleptic patients. PMID: 30540615 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - December 11, 2018 Category: Anesthesiology Authors: Hershner S, Kakkar R, Chung F, Singh M, Wong J, Auckley D Tags: Anesth Analg Source Type: research

Knowledge Gaps in the Perioperative Management of Adults With Narcolepsy: A Call for Further Research.
Abstract There is increasing awareness that sleep disorders may be associated with increased perioperative risk. The Society of Anesthesia and Sleep Medicine created the Narcolepsy Perioperative Task Force: (1) to investigate the current state of knowledge of the perioperative risk for patients with narcolepsy, (2) to determine the viability of developing perioperative guidelines for the management of patients with narcolepsy, and (3) to delineate future research goals and clinically relevant outcomes. The Narcolepsy Perioperative Task Force established that there is evidence for increased perioperative risk in pa...
Source: Anesthesia and Analgesia - March 6, 2019 Category: Anesthesiology Authors: Hershner S, Dauvilliers Y, Chung F, Singh M, Wong J, Gali B, Kakkar R, Mignot E, Thorpy M, Auckley D Tags: Anesth Analg Source Type: research

Cardiovascular Parameters in a Swine Model of Normobaric Hypoxia Treated With 5-Hydroxymethyl-2-Furfural (5-HMF)
Conclusion: 5-HMF treatment decreased P50, improved SaO2, and mitigated increases in PAP in this swine model of NH. Introduction The reduction of barometric pressure at altitude is associated with reduced partial pressure of ambient Oxygen (PO2). With lower ambient PO2, it can be anticipated that alveolar (PAO2), arterial O2 (PaO2) and blood O2 content (CaO2) will decrease accordingly, resulting in a widely recognized decrease in maximal O2 consumption (VO2) (Dill and Adams, 1972; Lucas et al., 2011). In humans, with acute exposure to altitude, maximal VO2 decrements are measurable at elevations even as low as 580 ...
Source: Frontiers in Physiology - April 17, 2019 Category: Physiology Source Type: research

Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned.
CONCLUSION: A reproducible percutaneous model of severe IMR in swine is feasible with a guided anesthetic and peri-operative approach. This model can serve as a platform to better understand the mechanism of IMR and subsequently to test novel repair techniques. PMID: 32553769 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - June 14, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Pasrija C, Quinn RW, Alkhatib H, Tran D, Bernstein D, Rice M, Kotloff E, Morales D, D'Ambra MN, Vesely M, Gammie JS Tags: Ann Thorac Surg Source Type: research

Experimental study in vivo ablation of swine pancreas using high-intensity focused ultrasound
Conclusions: It was feasible and safe to use HIFU for ablation of the pancreas in swine.
Source: Journal of Cancer Research and Therapeutics - March 31, 2019 Category: Cancer & Oncology Authors: Guanghui Huang Xin Ye Xia Yang Aimin Zheng Wenhong Li Jiao Wang Xiaoying Han Zhigang Wei Min Meng Yang Ni Chengkun Qin Xingbo Fei Liulin Xiong Source Type: research

Ventricular fibrillation: are swine a sensitive species?
Conclusions Swine are about three times as sensitive to the electrical induction of VF as are humans.
Source: Journal of Interventional Cardiac Electrophysiology - January 16, 2015 Category: Cardiology Source Type: research

Impaired pulmonary vasomotor control in exercising swine with multiple comorbidities
In conclusion, common comorbidities directly alter pulmonary vascular control, by enhanced PDE5 and endothelin-mediated vasoconstrictor influences, well before overt left ventricular backward failure or pulmonary hypertension develop.
Source: Basic Research in Cardiology - September 12, 2021 Category: Cardiology Source Type: research

Temperature modulation with an esophageal heat transfer device- a pediatric swine model study
Conclusions: An esophageal heat transfer device successfully modulated the temperature in a pediatric swine model. This approach to temperature modulation may offer a useful new modality to control temperature in conditions warranting temperature management (such as maintenance of normothermia, induction of hypothermia, fever control, or malignant hyperthermia).
Source: BMC Anesthesiology - February 4, 2015 Category: Anesthesiology Authors: Erik KulstadMelissa NaimanPatrick ShanleyFrank GarrettTodd HaryuDonald WallerFarshid AzarafroozD Courtney Source Type: research

Comparison of Isoflurane and α-Chloralose in an Anesthetized Swine Model of Acute Pulmonary Embolism Producing Right Ventricular Dysfunction.
Abstract Pulmonary embolism (PE) is a leading cause of sudden cardiac death, and a model is needed for testing potential treatments. In developing a model, we compared the hemodynamic effects of isoflurane and α-chloralose in an acute swine model of PE because the choice of anesthesia will likely affect the cardiovascular responses of an animal to PE. At baseline, swine that received α-chloralose (n = 6) had a lower heart rate and cardiac output and higher SpO2, end-tidal CO2, and mean arterial pressure than did those given isoflurane (n = 9). After PE induction, swine given α-chloralose compared with isofluran...
Source: Comparative Medicine - March 4, 2015 Category: Zoology Authors: Beam DM, Neto-Neves EM, Stubblefield WB, Alves NJ, Tune JD, Kline JA Tags: Comp Med Source Type: research

High fat feeding promotes obesity and renal inflammation and protects against post cardiopulmonary bypass acute kidney injury in swine
Conclusions: A high fat diet promoted obesity and renal inflammation and prevented post CPB AKI in swine. This study provides insights into the obesity paradox and the failure of anti-inflammatory interventions to improve clinical outcomes in patients at risk of post cardiac surgery AKI.
Source: Critical Care - October 31, 2013 Category: Intensive Care Authors: Philippa SleemanNishith PatelHua LinGraham WalkdenParamita RayGavin WelshSimon SatchellGavin Murphy Source Type: research

Anesthesia in swine : Optimizing a laboratory model to optimize translational research.
In conclusion, swine are an excellent laboratory animal for bench to bedside research and can be managed properly when basic knowledge and adequate skills on careful handling, anesthesia and surgical considerations are present. PMID: 25384955 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - November 12, 2014 Category: Anesthesiology Authors: Pehböck D, Dietrich H, Klima G, Paal P, Lindner KH, Wenzel V Tags: Anaesthesist Source Type: research

A novel and effective balanced intravenous-inhalant anaesthetic protocol in Swine by using unrestricted drugs.
This study demonstrates that the proposed balanced intravenous-inhalant protocol permits to carry out a very effective, stable and safe anaesthesia in swine undergoing deep anaesthesia. PMID: 25030879 [PubMed - in process]
Source: Experimental Animals - December 2, 2014 Category: Research Tags: Exp Anim Source Type: research