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During Swine Flu Pandemic, Co-Infections Not Associated With Worse Outcomes
A study at Rhode Island Hospital has found that despite complications, patients co-infected with the pandemic 2009-2010 influenza A H1N1 (pH1N1) and a second respiratory virus were not associated with worse outcomes or admission to the hospital's intensive care unit. The study is published online in the journal PLOS ONE. "There is scant data in the literature regarding the incidence and impact of simultaneous infection by two respiratory viruses, particularly in adults," said senior investigator Leonard Mermel, D.O...
Source: Health News from Medical News Today - April 12, 2013 Category: Consumer Health News Tags: Swine Flu Source Type: news
The adjuvant component α-tocopherol triggers via modulation of Nrf2 the expression and turnover of hypocretin in vitro and its implication to the development of narcolepsy.
CONCLUSION: In case of a genetic predisposition (DQB1*602) α-tocopherol could confer to development of narcolepsy by activation of Nrf2 that finally leads to an elevated formation of longer hypocretin-derived fragments that can be presented by HLA-subtype DQB1*602. These cells are recognized by the immune system and due to their increased sensitivity to apoptotic stimuli they can be destroyed, finally leading to a lack of hypocretin.
PMID: 24721530 [PubMed - as supplied by publisher]
Source: Vaccine - April 7, 2014 Category: Allergy & Immunology Authors: Masoudi S, Ploen D, Kunz K, Hildt E Tags: Vaccine Source Type: research
Increased Risk Of Sleep Disorder In Children Who Received Swine Flu Vaccine
Results consistent with findings from Finland and Sweden, but may still be overestimated A study published on bmj.com today finds an increased risk of narcolepsy in children and adolescents who received the A/H1N1 2009 influenza vaccine (Pandemrix) during the pandemic in England. The results are consistent with previous studies from Finland and Sweden and indicate that the association is not confined to Scandinavian populations...
Source: Health News from Medical News Today - February 27, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news
Cold and flu warning: The dangers of too much acetaminophen
Cold and flu season is here.
Peruse the aisles of a local pharmacy or grocery store and you will find more than 30 over-the-counter medications available to treat the symptoms of fever, headache, sore throat, and achy muscles. Many of these “multi-symptom” products contain acetaminophen, the active ingredient in Tylenol. This means cold and flu sufferers who are using multiple combination cough and cold remedies may inadvertently be taking more acetaminophen than they intend — and putting themselves at risk for a serious complication: acetaminophen-induced liver toxicity.
Acetaminophen is the most commonly available ...
Source: New Harvard Health Information - January 27, 2016 Category: Consumer Health News Authors: Susan Farrell, MD Tags: Back Pain Cold and Flu Drugs and Supplements Pain Management Safety Source Type: news
What 1989 And The Golden Girls Tell Us About Medicine Today
Today, 1989 may be most associated with Taylor Swift: It is the album that won her a second Grammy for Album of the Year. Not only that, it happens to be the year Swift was born--such a long, long time ago!
People under 35 have no personal memory of 1980s pop culture, which is ironic since Swift's album in part pays homage to it. In the real 1989 (no offense to Swift and the 10 co-producers who made the album), all sorts of revolutions took place: Mr. Gorbachev tore down that pesky wall, for example. America's greatest antagonist, the Soviet Union, collapsed in 1989. Brazil conducted its first democratic presidential ...
Source: Healthy Living - The Huffington Post - September 23, 2016 Category: Consumer Health News Source Type: news
Scientists divided over device that 'remotely detects hepatitis C'
Developers say C-Fast – developed from bomb detection technology – will revolutionise diagnosis of other diseasesThe device the doctor held in his hand was not a contraption you expect to find in a rural hospital near the banks of the Nile.For a start, it was adapted from a bomb detector used by the Egyptian army. Second, it looked like the antenna for a car radio. Third, and most bizarrely, it could – the doctor claimed – remotely detect the presence of liver disease in patients sitting several feet away, within seconds.The antenna was a prototype for a device called C-Fast. If its Egyptian developers are to be be...
Source: Guardian Unlimited Science - February 25, 2013 Category: Science Authors: Patrick Kingsley Tags: Middle East and North Africa World news Egypt guardian.co.uk Medical research Society Features Hepatitis C Science Source Type: news
Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France
An increased incidence of narcolepsy in children was detected in Scandinavian countries where pandemic H1N1 influenza ASO3-adjuvanted vaccine was used. A campaign of vaccination against pandemic H1N1 influenza was implemented in France using both ASO3-adjuvanted and non-adjuvanted vaccines. As part of a study considering all-type narcolepsy, we investigated the association between H1N1 vaccination and narcolepsy with cataplexy in children and adults compared with matched controls; and compared the phenotype of narcolepsy with cataplexy according to exposure to the H1N1 vaccination. Patients with narcolepsy-cataplexy were i...
Source: Brain - July 24, 2013 Category: Neurology Authors: Dauvilliers, Y., Arnulf, I., Lecendreux, M., Monaca Charley, C., Franco, P., Drouot, X., d'Ortho, M.-P., Launois, S., Lignot, S., Bourgin, P., Nogues, B., Rey, M., Bayard, S., Scholz, S., Lavault, S., Tubert-Bitter, P., Saussier, C., Pariente, A., on beha Tags: Original Articles Source Type: research
How Can People With Narcolepsy Drive Safely?
For many people, avoiding fatigued driving means staying off the roads after pulling an all-nighter. But imagine driving when you have narcolepsy, a brain disorder that causes people to suffer from chronic daytime drowsiness and fall asleep suddenly. With narcolepsy, the dangers of drowsy driving become a perennial threat.
What can a person with narcolepsy do ― never drive?
Well, no, but there are some important caveats.
Joyce Scannell, an office manager at the Narcolepsy Network nonprofit who has had narcolepsy her whole life, says she never drives more than 20 minutes at a time.
“Luckily I work f...
Source: Science - The Huffington Post - July 12, 2016 Category: Science Source Type: news
Narcolepsy patients' blood ‐based miRNA expression profiling: miRNA expression differences with Pandemrix vaccination
ConclusionsWe identified miRNA expression patterns in narcolepsy patients that linked them to mRNA targets known to be involved in brain‐related pathways or brain disorders.
Source: Acta Neurologica Scandinavica - March 2, 2017 Category: Neurology Authors: N. Mosakhani, V. Sarhadi, P. Panula, M. Partinen, S. Knuutila Tags: ORIGINAL ARTICLE Source Type: research
Dissociative Symptoms are Highly Prevalent in Adults with Narcolepsy Type 1.
Conclusion: Dissociative symptoms are strikingly prevalent in adult patients with narcolepsy type 1. Although a formal diagnosis of dissociation disorder should not be made as the symptoms can be explained by narcolepsy as an underlying condition, the findings do illustrate the extent and severity of the dissociative symptoms. As for the pathophysiological mechanism, there may be symptom overlap between narcolepsy and dissociation disorder. However, there may also be a more direct link between disrupted sleep and dissociative symptoms. In either case, the high frequency of occurrence of dissociative symptoms should result ...
Source: Behavioral Sleep Medicine - February 17, 2021 Category: Sleep Medicine Authors: Quaedackers L, Droogleever Fortuyn H, Van Gilst M, Lappenschaar M, Overeem S Tags: Behav Sleep Med Source Type: research
Alterations in the structural covariance network of the hypothalamus in patients with narcolepsy
ConclusionWe found that the structural covariance network of the hypothalamus, as assessed from the subunit volumes of hypothalamic regions using a graph theoretical analysis, is different in patients with narcolepsy compared to healthy controls. These findings may contribute to the understanding of the pathogenesis of narcolepsy.
Source: Neuroradiology - January 11, 2022 Category: Radiology Source Type: research
The Rise of Zika
By Drs. David Niesel and Norbert Herzog, Medical Discovery News Have you noticed in the past few years, we seem to be continuously assaulted by microbial menaces? Some years back it was SARS, which set off a global panic. People were screened for fevers at many major international airports. Then came the West Nile virus, which started from a single case in New York and in a matter of years marched across the U.S. Who can forget the avian flu or swine flu, which happened around the same time? More recently, the MERS virus has emerged, with outbreaks in the Arabian Peninsula and then whole villages in Korea. We are just now ...
Source: Science - The Huffington Post - April 6, 2016 Category: Science Source Type: news
Dissociative Symptoms are Highly Prevalent in Adults with Narcolepsy Type 1
Conclusion: Dissociative symptoms are strikingly prevalent in adult patients with narcolepsy type 1. Although a formal diagnosis of dissociation disorder should not be made as the symptoms can be explained by narcolepsy as an underlying condition, the findings do illustrate the extent and severity of the dissociative symptoms. As for the pathophysiological mechanism, there may be symptom overlap between narcolepsy and dissociation disorder. However, there may also be a more direct link between disrupted sleep and dissociative symptoms. In either case, the high frequency of occurrence of dissociative symptoms should result ...
Source: Behavioral Sleep Medicine - February 17, 2021 Category: Sleep Medicine Authors: Laury Quaedackers Hal Droogleever Fortuyn Merel Van Gilst Martijn Lappenschaar Sebastiaan Overeem Source Type: research
Guillan-Barr é Syndrome after First Vaccination Dose against COVID-19: Case Report
In conclusion, we report a case of Guillan-Barré syndrome after COVID-19 vaccine in a young patient with a rapid diagnosis and prompt administration of immunoglobulins.PMID:34779385 | DOI:10.14712/18059694.2021.31
Source: Acta Medica: Hradec Kralove - November 15, 2021 Category: General Medicine Authors: Daniel Čenščák Leo š Ungermann Ivana Štětkářová Edvard Ehler Source Type: research
