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Vaccination: Bird Flu (H5N1 Avian Influenza) Vaccine

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Swine Flu, Bird Flu And Pandemic Vaccination
As the world prepares for what may be the next pandemic strain of influenza virus, in the H7N9 bird flu, a new UC Irvine study reveals that the 2009 H1N1 swine flu pandemic was deadliest for people under the age of 65, while those 65 and over had greater immunity due to previous exposure to similar viruses. Deaths from flu pandemics tend to skew younger than those from seasonal flu because of "antigenic recycling," or the fact that some parts of flu viruses have already made the rounds...
Source: Health News from Medical News Today - May 25, 2013 Category: Consumer Health News Tags: Swine Flu Source Type: news

Four out of ten Brits may naturally show fewer flu symptoms
ConclusionA study of 1,414 unvaccinated people showed those with T cells targeting virus nucleoprotein still got infected by flu, but had fewer symptoms. The logic is that people with fewer symptoms are less likely to spread the virus through coughs and sneezes, which may slow the spread of both seasonal and pandemic flu strains.This is plausible, but was not directly tested in this study, so we don't know if it's true in real life. The research team suggested vaccines that boost T cell numbers might be worth exploring, as an alternative to those that try to stop virus infection altogether. An added potential benefit of th...
Source: NHS News Feed - June 16, 2015 Category: Consumer Health News Tags: Heart/lungs Medical practice Medication Swine flu Source Type: news

Could brain protein help people 'sleep off' the flu?
Conclusion This complex study suggests the AcPb protein is playing a role in regulating normal sleep and the response to flu infection in mice. At this stage, the implications of this research for humans are unclear, as differences between the species may mean the results would not be exactly the same in humans. While The Telegraph suggests this "could finally lead to an effective treatment for the [flu], which until now has eluded experts", we are a long way off knowing whether this is the case. What the researchers have shown – in mice – is if you remove this protein, mice don't fight the virus as we...
Source: NHS News Feed - January 13, 2015 Category: Consumer Health News Tags: Neurology Medication Heart/lungs Swine flu Source Type: news

Swine flu is back again: a review.
Abstract Flu viruses have mainly affected humans, birds and pigs worldwide. During the past 10 years these viruses are in limelight at a global level due to pandemic threats of Avian/Bird Flu and Swine Flu and their public health impacts, with added pandemic of swine flu virus recently. The current ongoing episodes of bird flu and swine flu are beyond the control, when and where or which country they start with nobody can predict. The continuous evolution and emergence of new strains indicate that the flu viruses are becoming more and more dangerous and this situation has posed a challenge to researchers to discov...
Source: Pakistan Journal of Biological Sciences: PJBS - November 1, 2012 Category: Biomedical Science Authors: Dhama K, Verma AK, Rajagunalan S, Deb R, Karthik K, Kapoor S, Mahima, Tiwari R, Panwar PK, Chakraborty S Tags: Pak J Biol Sci Source Type: research

Scientists concerned at H7N9 bird flu outbreak that has killed 24 people
• Virus killing a fifth of those infected in China• World Health Organisation considers it a serious threatScientists are seriously concerned about a new bird flu virus that is causing severe disease in China, killing a fifth of all those it infects.So far, the virus, known as H7N9, is being transmitted only to humans from chickens, but there are worries that it could mutate into a form that could be passed from one person to another. Five mutations are known to be necessary for that to happen – H7N9 already has two of them. If that occurred, it could spread worldwide with lethal effect.According to the World Health ...
Source: Guardian Unlimited Science - May 1, 2013 Category: Science Authors: Sarah Boseley Tags: Bird flu Asia Pacific World news Infectious diseases Health guardian.co.uk Medical research Microbiology China Editorial Science Source Type: news

Researchers 'a step closer' to universal flu vaccine
Conclusion These studies have developed two different flu vaccines that could potentially offer broader protection against a variety of flu strains than current vaccines. As yet, this research has only been conducted in animals, with one study showing an effect against different flu strains in mice and monkeys, and the other showing an effect in mice and ferrets. As monkeys are more similar to humans than mice or ferrets, the results from these experiments are likely to be the most representative of what would happen in humans. While the results are encouraging, it is likely that additional lab and animal research on bo...
Source: NHS News Feed - August 25, 2015 Category: Consumer Health News Tags: Medical practice Medication Heart/lungs Swine flu Source Type: news

Solving the Mystery Flu That Killed 50 Million People
MoreCalifornia Bill Banning ‘Affluenza’ Defense Is Nixed7 Ebola Patients in Guinea Fight Off the Disease4 Diseases Making a Comeback Thanks to Anti-VaxxersYears ago the environmental historian Alfred Crosby was at Washington State University, where he was teaching at the time, when on a whim he decided to pick up an old almanac from 1917. (This is apparently the kind of thing historians like to do in their spare time.) He looked up the U.S. life expectancy in that year—it was about 51 years. He turned to the 1919 almanac, and found about the same figure. Then Crosby picked up the almanac from 1918. The U.S. l...
Source: TIME: Top Science and Health Stories - April 29, 2014 Category: Science Authors: Bryan Walsh Tags: Uncategorized 1918 pandemic avian flu bird flu death rates H1N1 H5N1 H7N9 health immune system influenza Spanish flu Source Type: news

New deadly strain of bird flu may have emerged
“Experts are concerned about the spread of a new strain of bird flu that has already killed one woman in China,” BBC News reports. The new strain, which has evolved from an existing bird flu virus called H10N8, has infected two people in China. A case report in The Lancet medical journal warns that potential for a new pandemic “should not be underestimated”. Their genetic tests of the strain suggests it has adapted to infect humans more easily.  That said, experts suggest there is currently no cause for alarm. There is no evidence that the new strain can pass between humans. Also, the woman who died of the ne...
Source: NHS News Feed - February 5, 2014 Category: Consumer Health News Tags: Swine flu QA articles Medical practice Source Type: news

Universal flu vaccine a step closer as scientists create experimental jabs
Annual vaccinations could be a thing of the past as scientists have successfully tested vaccines on animals infected with different strains of influenzaA universal flu vaccine that protects against multiple strains of the virus is a step closer after scientists created experimental jabs that work in animals.The vaccines prevented deaths or reduced symptoms in mice, ferrets and monkeys infected with different types of flu, raising hopes for a reliable alternative to the seasonal vaccine. Continue reading...
Source: Guardian Unlimited Science - August 25, 2015 Category: Science Authors: Ian Sample, science editor Tags: Medical research Science Flu Vaccines and immunisation Biology Microbiology Flu pandemic Health Bird flu Swine flu Source Type: news

Serious flu risk could be identified with genetic test
Findings show that the severity of infection can be partially governed by a person’s genetic make-up, and opens the door to new types of anti-viral drugsPeople who are at risk of falling seriously ill with the flu could be identified by a genetic test and encouraged to have the seasonal vaccination, researchers say.The NHS offers flu jabs for people who are known to be most in danger from the virus, including the over-65s, pregnant women, and those with underlying health problems, such as asthma. Continue reading...
Source: Guardian Unlimited Science - September 8, 2015 Category: Science Authors: Ian Sample, science editor Tags: Genetics Science Flu Swine flu Bird flu Biology Vaccines and immunisation Health British Science Festival Source Type: news

Flu research may lead to universal vaccine
Conclusion This research has identified that CD8+ T-cells are linked with protection against different strains of influenza. They are also linked with reduced severity of flu. The authors note that current vaccines that use inactivated forms of the flu virus protect against specific strains, and do not induce a strong maintained T-cell response. They suggest that, in light of their findings, this may be the reason why they produce limited protection across different subtypes of influenza virus. They say that further testing is needed to see if the live vaccines being used are better at producing cross-subtype protection, ...
Source: NHS News Feed - September 23, 2013 Category: Consumer Health News Tags: Heart/lungs Medication Medical practice Source Type: news

Predicting hotspots for future flu outbreaks
This year's unusually long and rocky flu season would be nothing compared to the pandemic that could occur if bird flu became highly contagious among humans, which is why UCLA researchers and their colleagues are creating new ways to predict where an outbreak could emerge.   "Using surveillance of influenza cases in humans and birds, we've come up with a technique to predict sites where these viruses could mix and generate a future pandemic," said lead author Trevon Fuller, a UCLA postdoctoral research fellow at the Institute of the Environment and Sustainability's Center for Tropical Research.   The researchers'...
Source: UCLA Newsroom: Health Sciences - March 14, 2013 Category: Universities & Medical Training Source Type: news

First childhood flu helps explain why virus hits some people harder than others
Why are some people better able to fight off the flu than others? Part of the answer, according to a new study, is related to the first flu strain we encounter in childhood.Scientists from UCLA and the University of Arizona have found that people ’s ability to fight off the flu virus is determined not only by the subtypes of flu they have had throughout their lives, but also by the sequence in which they are been infected by the viruses. Their study is published in the open-access journal PLoS Pathogens.The research offers an explanation for why some people fare much worse than others when infected with the same strain...
Source: UCLA Newsroom: Health Sciences - February 4, 2020 Category: Universities & Medical Training Source Type: news

First time flu infection may affect lifetime immunity
Conclusion This modelling study shows how the strains of influenza A – "bird flu" – circulating when a person is born give them lifelong protection against new subtypes with the same H protein groups. The researchers call this immune imprinting. This may help to explain the high severity and mortality rate seen among certain groups. For example, the massive flu pandemic of 1918 was an H1N1 strain. This had a very high fatality rate among young adults, which the researchers consider may have been because when they were born (between 1880 and 1900), H3 was the dominant strain. Therefore they had no protection w...
Source: NHS News Feed - November 14, 2016 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news