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Fight Aging! Newsletter, August 8th 2022
In conclusion, aging research will benefit from a better definition of how specific regulators map onto age-dependent change, considered on a phenotype-by-phenotype basis. Resolving some of these key questions will shed more light on how tractable (or intractable) the biology of aging is. Does Acarbose Extend Life in Short Lived Species via Gut Microbiome Changes? https://www.fightaging.org/archives/2022/08/does-acarbose-extend-life-in-short-lived-species-via-gut-microbiome-changes/ Acarbose is one of a few diabetes medications shown to modestly slow aging in short-lived species. Researchers here take a ...
Source: Fight Aging! - August 7, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Aging and the Severity of Inflammatory Infectious Disease Such as SARS-CoV-2
This article provides a pathophysiologic view of COVID-19 in older adults within the frame of inflammaging, with a focus on antiinflammatory treatments for acute and postacute disease. How can Biology of Aging Explain the Severity of COVID-19 in Older Adults Aging has been identified as one of the most relevant risk factors for poor outcomes in COVID-19 disease, independently from the presence of preexisting diseases. The COVID-19 mortality risk sharply increases for elderly subjects, as showed by the reports of China, Italy, and the United States. In particular, in Italy, case fatality rate for patient a...
Source: Fight Aging! - August 2, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
July 28, 2022 Edition-----Sadly the war drags on, Biden seems to be pretty impotent on most policy fronts and the US seems to be heading into a recession. Not good,In the UK the choosing the next PM is off and running as the country and Europe are cooling down after a heatwave (for them) of biblical proportions!In OZ Parliament is meeting which is when the rubber will really hit the road as a new virus wave runs out of control still! We need to do more to control it as we realise just how bad long COVID is!-----Major Issues.-----https://www.afr.com/policy/economy/how-a-nobel-laureate-got-australian-economists-offside-...
Source: Australian Health Information Technology - July 28, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

5 COVID-19 Discussions That Will Dominate 2022
Discussions That Will Dominate 2022 appeared first on The Medical Futurist.
Source: The Medical Futurist - January 11, 2022 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Covid-19 Forecast Artificial Intelligence in Medicine Science Fiction vaccination pandemic vaccine pfizer fatigue booster Source Type: blogs

Fight Aging! Newsletter, June 14th 2021
In conclusion, a number of high-income countries, changes in health expectancies over time have not kept pace with the growth in life expectancy. That is, people are living longer but disability and poor health are occupying an increasing proportion of later life. Our findings suggest that countries still need to make significant progress to achieve the WHO's Decade of Healthy Ageing goal of healthier, longer lives for all. Progress on Understanding Why Human Growth Hormone Receptor Variants are Associated with Greater Longevity https://www.fightaging.org/archives/2021/06/progress-on-understanding-why-human-gro...
Source: Fight Aging! - June 13, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

This Is How We Can End COVID In 6 Steps
There is frankly one question today on everybody’s mind: when will all this end? And although deep inside we all know this won’t really be over till it’s… over, we strive for a definite answer. Say, in June. The sad news is, the pandemic will be with us until we finally take individual responsibility. Instead of trying to avoid the jab, we should get ourselves vaccinated as soon as possible. Why? I’ll tell you in six simple, self-explanatory logical steps. 1. COVID-19 will end when the coronavirus becomes endemic A virus becomes endemic when it has a constant presence within a population in a certain ar...
Source: The Medical Futurist - February 25, 2021 Category: Information Technology Authors: Judit Kuszkó Tags: Covid-19 Digital Health Research E-Patients Healthcare ethical vaccination coronavirus lockdown vaccine flu hospitals Italy Spanish flu Source Type: blogs

This Is How We Can End COVID In 6 Logical Steps
There is frankly one question today on everybody’s mind: when will all this end? And although deep inside we all know this won’t really be over till it’s… over, we strive for a definite answer. Say, in June. The sad news is, the pandemic will be with us until we finally take individual responsibility. Instead of trying to avoid the jab, we should get ourselves vaccinated as soon as possible. Why? I’ll tell you in six simple, self-explanatory logical steps. 1. COVID-19 will end when the coronavirus becomes endemic A virus becomes endemic when it has a constant presence within a population in a certain ar...
Source: The Medical Futurist - February 25, 2021 Category: Information Technology Authors: Judit Kuszkó Tags: Covid-19 Digital Health Research E-Patients Healthcare ethical vaccination coronavirus lockdown vaccine flu hospitals Italy Spanish flu Source Type: blogs

Can the Government Mandate a Covid-19 Vaccine? Will It Have To?
Conclusion As governments assess how to contend with reaching effective levels of vaccination, they are preparing to tread carefully around vaccine skepticism while transparently and apolitically addressing common concerns about safety and due process. Attitudes could change as vaccines are distributed to the public and, hopefully, demonstrate safety and effectiveness, encouraging individuals to rapidly vaccinate. For government, a heavy-handed approach could backfire, fueling further anti-government/anti-science sentiment, but not pursuing vaccination with ample vigor could mean a prolonged timeline for co...
Source: The Health Care Blog - November 23, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy COVID-19 vaccine Phillip Meylan Source Type: blogs

Our Top 8 Digital Health Solutions Addressing Long COVID
Yes, the COVID-19 pandemic is long. Since the WHO characterised the virus’ spread as a pandemic in March, cases have been climbing; countries are facing a second wave and are entering lockdown 2.0; and many aspects of our current lifestyle will continue through 2021. But this isn’t what we mean by “long COVID.” This newly-minted term refers to patients experiencing long-term sequelae of a COVID infection. It’s not an exact medical term as it is a patient-made one apparently first used by Elisa Perego in a tweet to describe her own experience. Additionally, two patients can have different #longcovid experiences...
Source: The Medical Futurist - November 17, 2020 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine E-Patients Health Sensors & Trackers Healthcare Design Healthcare Policy Portable Medical Diagnostics Telemedicine & Smartphones AI diabetes lumosity wearables sleep tracking Fitbit mental heal Source Type: blogs

Long COVID: 8 Ways Digital Health Can Address The Symptoms
Yes, the COVID-19 pandemic is long. Since the WHO characterised the virus’ spread as a pandemic in March, cases have been climbing; countries are facing a second wave and are entering lockdown 2.0; and many aspects of our current lifestyle will continue through 2021. But this isn’t what we mean by “long COVID.” This newly-minted term refers to patients experiencing long-term sequelae of a COVID infection. It’s not an exact medical term as it is a patient-made one apparently first used by Elisa Perego in a tweet to describe her own experience. Additionally, two patients can have different #longcovid experiences...
Source: The Medical Futurist - November 17, 2020 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine E-Patients Health Sensors & Trackers Healthcare Design Healthcare Policy Portable Medical Diagnostics Telemedicine & Smartphones AI diabetes lumosity wearables sleep tracking Fitbit mental heal Source Type: blogs

Disease names – what do they mean?
In the midst of the continuing pandemic, World Dictionary Day seems like the perfect occasion to consider the meaning and origin behind some of the most well-known disease names. We’ve been speaking with Dr. Steve Berger, our co-founder, to learn more. CORONAVIRUSES Let’s start with the obvious one. COVID 19, which began as a localized outbreak of “Novel Coronavirus” infection,  is now a name almost every household in the world will know. COVID-19 comes from COrona VIrus Disease which first appeared in 2019, with the disease itself being caused by the SARS-CoV-2 virus. SARS was a prominent name back in the early 2...
Source: GIDEON blog - October 16, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Source Type: blogs

The Story of an American Mask Distributor
By SAURABH JHA Seven weeks before President Trump declared COVID-19 a federal emergency heralding the economic lockdown, Jesse’s customers began cutting their orders. Jesse sells garments and cotton, imported predominantly from India, to wholesalers and retailers, big and small, in malls across the North East corridor.  His business had a good January. December was like any December. But February was different.  His customers, reassuring him that it wasn’t personal, were predicting a falling demand for their products because of COVID-19. They may be over reacting, but better shortage than glut, they felt. J...
Source: The Health Care Blog - August 13, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy masks Pandemic Saurabh Jha Source Type: blogs

Fight Aging! Newsletter, August 10th 2020
This study aimed to characterize the role of BDNF in age-related microglial activation. Initially, we found that degrees of microglial activation were especially evident in the substantia nigra (SN) across different brain regions of aged mice. The levels of BDNF and TrkB in microglia decreased with age and negatively correlated with their activation statuses in mice during aging. Interestingly, aging-related microglial activation could be reversed by chronic, subcutaneous perfusion of BDNF. Peripheral lipopolysaccharide (LPS) injection-induced microglial activation could be reduced by local supplement of BDNF, while shTrkB...
Source: Fight Aging! - August 9, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

COVID herd immunity: At hand or forever elusive?
By MICHEL ACCAD, MD With cases of COVID-19 either disappeared or rapidly diminishing from places like Wuhan, Italy, New York, and Sweden, many voices are speculating that herd immunity may have been reached in those areas and that it may be at hand in the remaining parts of the world that are still struggling with the pandemic.  Lockdowns should end—or may not have been needed to begin with, they conclude. Adding plausibility to their speculation is the discovery of biological evidence suggesting that prior exposure to other coronaviruses may confer some degree of immunity against SARS-CoV2, a...
Source: The Health Care Blog - July 30, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy immunity MICHEL ACCAD Pandemic Source Type: blogs

The 2020 Pandemic Election
The 2020 US election will be vicious, with a nasty pandemonium following a nasty pandemic. By SAURABH JHA, MD When the COVID-19 pandemic is dissected in the 2020 presidential election debates, Donald Trump will be at a disadvantage. The coronavirus has killed over 100,000 Americans and maimed thousands more. The caveat is that deaths per capita, rather than total deaths, better measure national failure, and by that metric the US fares better than Belgium, Italy and the United Kingdom. New York City owns a disproportionate share of the deaths, but this hyperconnected megapolis is an outlier whose misfortunes ...
Source: The Health Care Blog - July 15, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Politics Saurabh Jha Source Type: blogs