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Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men. « Back to Top Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/ Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
 September 08, 2022 Edition-----In the US we are seeing the outcomes of Climate Change really of and running with droughts and fires etc. Biden amped up the partisan divide with a fiery anti-Republican speech!In Russia the last leader of Soviet Russia died.In the UK we have a new PM while in Europe the energy crisis is just getting worse.In OZ we have survived the Jobs and Skills Summit with 36 prearranged outcomes. Stage management +++ in action. The GP crisis is not being addressed fully and worries regarding the Global Economy - esp. China - worsen.-----Major Issues.-----https://www.afr.com/work-and-careers/educati...
Source: Australian Health Information Technology - September 8, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Commentators and Journalists Weigh In On Digital Health And Related Privacy, Safety, Social Media And Security Matters. Lots Of Interesting Perspectives - August 23, 2022.
-----This weekly blog is to explore the news around the larger issues around Digital Health, data security, data privacy, AI / ML. technology, social media and related matters.I will also try to highlightADHA Propagandawhen I come upon it.Just so we keep count, the latest Notes from the ADHA Board were dated 6 December, 2018 and we have seen none since! It ’s pretty sad!Note: Appearance here is not to suggest I see any credibility or value in what follows. I will leave it to the reader to decide what is worthwhile and what is not! The point is to let people know what is being said / published that I have come upon.-----h...
Source: Australian Health Information Technology - August 23, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, August 8th 2022
In conclusion, aging research will benefit from a better definition of how specific regulators map onto age-dependent change, considered on a phenotype-by-phenotype basis. Resolving some of these key questions will shed more light on how tractable (or intractable) the biology of aging is. Does Acarbose Extend Life in Short Lived Species via Gut Microbiome Changes? https://www.fightaging.org/archives/2022/08/does-acarbose-extend-life-in-short-lived-species-via-gut-microbiome-changes/ Acarbose is one of a few diabetes medications shown to modestly slow aging in short-lived species. Researchers here take a ...
Source: Fight Aging! - August 7, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 1st 2022
In this study, we used the recently released Infinium Mouse Methylation BeadChip to compare such epigenetic modifications in C57BL/6 (B6) and DBA/2J (DBA) mice. We observed marked differences in age-associated DNA methylation in these commonly used inbred mouse strains, indicating that epigenetic clocks for one strain cannot be simply applied to other strains without further verification. Interestingly, the CpGs with highest age-correlation were still overlapping in B6 and DBA mice and included the genes Hsf4, Prima1, Aspa, and Wnt3a. Furthermore, Hsf4, Aspa, and Wnt3a revealed highly significant age-associated DNA methyla...
Source: Fight Aging! - July 31, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
July 28, 2022 Edition-----Sadly the war drags on, Biden seems to be pretty impotent on most policy fronts and the US seems to be heading into a recession. Not good,In the UK the choosing the next PM is off and running as the country and Europe are cooling down after a heatwave (for them) of biblical proportions!In OZ Parliament is meeting which is when the rubber will really hit the road as a new virus wave runs out of control still! We need to do more to control it as we realise just how bad long COVID is!-----Major Issues.-----https://www.afr.com/policy/economy/how-a-nobel-laureate-got-australian-economists-offside-...
Source: Australian Health Information Technology - July 28, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, August 30th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out mo...
Source: Fight Aging! - August 29, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Immune-Boosting Hacks to Remember as the World Reopens
You might think the pandemic has ended by the way many people behave. However, threats remain for many, including the unvaccinated and the immunocompromised. Even if you are otherwise healthy, the novel coronavirus isn’t the only germ against which you need to protect yourself. Please follow these eight immune-boosting hacks as society reopens. 1. Eat a Healthy Diet A plant-based diet rich in antioxidants and other vital nutrients is your best bet for providing your body with the requisite building blocks for ongoing health. The phytonutrients contained in plants neutralize toxins from pollution, bacteria and vi...
Source: PickTheBrain | Motivation and Self Improvement - June 28, 2021 Category: Consumer Health News Authors: Kara Reynolds Tags: featured health and fitness philosophy self education self-improvement covid protection virus Source Type: blogs

Fight Aging! Newsletter, June 14th 2021
In conclusion, a number of high-income countries, changes in health expectancies over time have not kept pace with the growth in life expectancy. That is, people are living longer but disability and poor health are occupying an increasing proportion of later life. Our findings suggest that countries still need to make significant progress to achieve the WHO's Decade of Healthy Ageing goal of healthier, longer lives for all. Progress on Understanding Why Human Growth Hormone Receptor Variants are Associated with Greater Longevity https://www.fightaging.org/archives/2021/06/progress-on-understanding-why-human-gro...
Source: Fight Aging! - June 13, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Your New Life In 2021 (Mid-Post COVID)
At the beginning of the pandemic, we wrote a lot about how the pandemic should and could be handled. In addition to providing real-world advice on what technology can do to support us (like Digital Health Apps To Use During Quarantine or The State of A.I. in the Fight Against COVID-19), we often provided forecasts (When And How Will COVID End?) and predictions about the management and the potential outcome of the epidemic (Will There Be A Second Wave). We even created an entire handbook to give away for free! After drawing attention to the privacy and data protection issues raised by the pandemic (we issued a guide for ...
Source: The Medical Futurist - May 6, 2021 Category: Information Technology Authors: Judit Kuszkó Tags: Covid-19 Forecast 3D Printing science telemedicine vaccination contact tracing cdc pfizer mask mRNA J&J herd immunity Uğur Şahin Karl Schroeder Source Type: blogs

What Can We Expect From 2021: The COVID Perspective
Nearing the end of 2020, we are globally far from seeing the end of the pandemic that ruled (and ruined) 2020. Every day we see hundreds of thousands of new cases of coronavirus infections, with the WHO reporting a record one-day rise, while people have a hard time complying with the strict safety measures again. We are all waiting for this nightmare to stop, but will it ever? How long, ‘till we need to keep masks on and stay away from grandma? After this dystopian 2020, how are we looking at 2021? No one knows for sure. With countries being knee-deep in the second wave, everyone is waiting for the vaccines to put an ...
Source: The Medical Futurist - October 15, 2020 Category: Information Technology Authors: Judit Kuszkó Tags: Forecast Digital Health Research Future of Medicine Science Fiction fake news vaccination covid covid19 pandemic vaccine hoax flu Oxfam COVAX olympics Source Type: blogs

Microfluidic Test for Viral Antibodies Takes Just 20 Minutes
Researchers at Hokkaido University in Japan have developed a microfluidic test that can detect antibodies against a viral infection. So far, the test has been optimized to detect avian flu, but could be adapted to detect antibodies against the virus ...
Source: Medgadget - May 27, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Materials Medicine Public Health Source Type: blogs

Research Provides No Basis for Pandemic Travel Bans
CONCLUSIONThe pre ‐​COVID‐​19 research is unanimous that governments cannot expect to rely on travel restrictions to prevent the spread of pandemics similar to influenza. Travel restrictions do not prevent the spread of disease and may only delay it for a few days or weeks if implemented prior to the interna tional transmission of the disease. The Trump administration’s travel restrictions waited until after the virus had already entered the United States, and they exempted many travelers from China, not to mention the rest of the world.[30]The research shows that the Trump administration should have known that ...
Source: Cato-at-liberty - April 15, 2020 Category: American Health Authors: David J. Bier Source Type: blogs