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Fight Aging! Newsletter, September 19th 2022
Conclusion Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life. Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
 September 08, 2022 Edition-----In the US we are seeing the outcomes of Climate Change really of and running with droughts and fires etc. Biden amped up the partisan divide with a fiery anti-Republican speech!In Russia the last leader of Soviet Russia died.In the UK we have a new PM while in Europe the energy crisis is just getting worse.In OZ we have survived the Jobs and Skills Summit with 36 prearranged outcomes. Stage management +++ in action. The GP crisis is not being addressed fully and worries regarding the Global Economy - esp. China - worsen.-----Major Issues.-----https://www.afr.com/work-and-careers/educati...
Source: Australian Health Information Technology - September 8, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Weekly Australian Health IT Links – 1 August, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----Quite a lot this week – especially regarding the NBN and Labor trying to regain control of what it is actually for – service provision – and not making a huge profit – in their view. Love the new Minister has ambitions to be maximally photogenic and not a ‘techie’!Otherwise all sorts of fun things!-----https://www.ausd...
Source: Australian Health Information Technology - August 1, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
July 28, 2022 Edition-----Sadly the war drags on, Biden seems to be pretty impotent on most policy fronts and the US seems to be heading into a recession. Not good,In the UK the choosing the next PM is off and running as the country and Europe are cooling down after a heatwave (for them) of biblical proportions!In OZ Parliament is meeting which is when the rubber will really hit the road as a new virus wave runs out of control still! We need to do more to control it as we realise just how bad long COVID is!-----Major Issues.-----https://www.afr.com/policy/economy/how-a-nobel-laureate-got-australian-economists-offside-...
Source: Australian Health Information Technology - July 28, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Avian influenza (bird flu)
My local park has notices up about an outbreak.  Here are sources of latest official information (for the UK).  Travel related information is at the end of the post. In addition to the sites below try your local authority ' s website.Animal and Plant Health Agency reports relating to wild birdsDEFRA and APHA, preliminary outbreak assessment, for Europe, Russia and the UK - includes Weekly disease reportsDEFRA and APHA, guidanceDepartment of Agriculture, Environment and Rural Affairs (Northern Ireland), Avian influenzaHealth and Safety Executive, Avian influenza(PDF) (information particularly for those i...
Source: Browsing - January 26, 2022 Category: Databases & Libraries Tags: avian influenza Source Type: blogs

Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 11th 2021
This study demonstrates the potential of a natural (o-Vanillin) and a synthetic (RG-7112) senolytic compounds to remove senescent IVD cells, decrease SASP factors release, reduce the inflammatory environment and enhance the IVD matrix production. Removal of senescent cells, using senolytics drugs, could lead to improved therapeutic interventions and ultimately decrease pain and a provide a better quality of life of patients living with intervertebral disc degeneration and low back pain. From Ying Ann Chiao of Oklahoma Medical Research Foundation: Mitochondrial dysfunction plays a central role in aging and cardiovasc...
Source: Fight Aging! - January 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, December 28th 2020
In conclusion, our study demonstrated that the molecular processes of aging are relatively subtle in their progress, and the aging process of every tissue depends on the tissue's specialized function and environment. Hence, individual gene or process alone cannot be described as the key of aging in the whole organism. Mouse Age Matters: How Age Affects the Murine Plasma Metabolome A large part of metabolomics research relies on experiments involving mouse models, which are usually 6 to 20 weeks of age. However, in this age range mice undergo dramatic developmental changes. Even small age differences may l...
Source: Fight Aging! - December 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What Can We Expect From 2021: The COVID Perspective
Nearing the end of 2020, we are globally far from seeing the end of the pandemic that ruled (and ruined) 2020. Every day we see hundreds of thousands of new cases of coronavirus infections, with the WHO reporting a record one-day rise, while people have a hard time complying with the strict safety measures again. We are all waiting for this nightmare to stop, but will it ever? How long, ‘till we need to keep masks on and stay away from grandma? After this dystopian 2020, how are we looking at 2021? No one knows for sure. With countries being knee-deep in the second wave, everyone is waiting for the vaccines to put an ...
Source: The Medical Futurist - October 15, 2020 Category: Information Technology Authors: Judit Kuszkó Tags: Forecast Digital Health Research Future of Medicine Science Fiction fake news vaccination covid covid19 pandemic vaccine hoax flu Oxfam COVAX olympics Source Type: blogs

Fight Aging! Newsletter, September 7th 2020
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - September 6, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Will There Be A Second Wave Of COVID-19?
In short? Yes, there most certainly will. Or, looking at it from another perspective, there might not be a second wave as the first one won’t end. In any case, which scenario is more probable depends on your country’s leadership and decisions and whether people will be compliant enough to go along with the restrictions. Because how governments are preparing for it over the next few weeks will be crucial in the fight against the pandemic. The search is still on for a vaccine and it certainly won’t be ready by the time experts say the second wave hits the stage. Technically, to talk about a second wave, the firs...
Source: The Medical Futurist - July 30, 2020 Category: Information Technology Authors: Judit Kuszkó Tags: Digital Health Research Security & Privacy Telemedicine & Smartphones vaccination coronavirus covid19 vaccine research leadership pandemic second wave flatten the curve researchers Anthony Fauci Mike Pence lockdown Source Type: blogs

The 2020 Pandemic Election
The 2020 US election will be vicious, with a nasty pandemonium following a nasty pandemic. By SAURABH JHA, MD When the COVID-19 pandemic is dissected in the 2020 presidential election debates, Donald Trump will be at a disadvantage. The coronavirus has killed over 100,000 Americans and maimed thousands more. The caveat is that deaths per capita, rather than total deaths, better measure national failure, and by that metric the US fares better than Belgium, Italy and the United Kingdom. New York City owns a disproportionate share of the deaths, but this hyperconnected megapolis is an outlier whose misfortunes ...
Source: The Health Care Blog - July 15, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Politics Saurabh Jha Source Type: blogs

Planning for Future Pandemics Including Smallpox Outbreaks: Interview with Dr. Phil Gomez, CEO, SIGA Technologies
The COVID-19 pandemic has had significant global consequences, with healthcare systems stretched to their limits, a growing death toll, and economic devastation as economies came grinding to a halt. The pandemic and its aftereffects will be with u...
Source: Medgadget - May 27, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Public Health Source Type: blogs

There Is No Time for That
By ROMAN ZAMISHKA, MPA Some of the most important engineering lessons were demonstrated on the tank battlefields of World War II when German Tigers faced off against Soviet T-34s. The Tiger tank was a technical masterpiece of for its time with many features that did not appear in allied tanks until after the war. Despite its much heavier armor it was able to match the speed of lighter enemy tanks and keep up with its own light tank scouts. The armor featured almost artisanally welded interlocking plates. The ammunition featured innovative electric trigger primers and high penetration tungsten shells. The double diff...
Source: The Health Care Blog - March 13, 2020 Category: Consumer Health News Authors: Christina Liu Tags: CORVID-19 Health Policy coronavirus COVID-19 Pandemic Roman Zamishka Source Type: blogs