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Drug: Hydroxychloroquine
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Clinical Research 101: Lecture 3
Now that we ' ve cleared away a bit of the underbrush, let ' s say you think that Eye of Newt Toe of Frog (Eontof) is potentially therapeutically useful against Creeping Crud (CC), and you want to test it. You face a whole lot of considerations. One is that you ' re going to need funding, which means you need to persuade somebody -- either the National Institutes of Health or a pharmaceutical company, most likely -- to invest in your idea. They ' re going to want to know that there ' s a reasonable chance of success with Eontof, and in the case of the pharmaceutical company that they can make money off of it, which brings ...
Source: Stayin' Alive - October 17, 2022 Category: American Health Source Type: blogs
Clinical Research 101: Lecture 2
Editor ' s note: Only about 15 million people so far have gotten the new bivalent Covid booster that ' s specifically formulated against the Omega variants that are currently circulating. I got it a few days ago, Walgreen ' s was offering appointments the same day! I got the flu shot at the same time, both absolutely free. Do it!So, picking up where we left off, to determine whether an intervention is beneficial, harmful or basically useless you ordinarily need a comparison group. There are actually exceptions. You don ' t need a randomized controlled trial for parachutes when jumping out of airplanes because you alr...
Source: Stayin' Alive - October 15, 2022 Category: American Health Source Type: blogs
It ’s still true: Not all the news about COVID-19 is bad
I thought the pandemic would be over by now. And I’m not alone; there were sophisticated models predicting a dramatic drop in the number of infections by the summer. And while there was understandable worry about the second wave, re-infection, and the coming flu season, there was good reason to believe we’d have the worst of the first wave well behind us.
Now, that all seems like wishful thinking. Here we are, over nine months into the pandemic, with more than 224,000 deaths, and more than 70,000 new cases and 800 deaths every day in this country as of late October. There are new hot spots popping up in the US and all ...
Source: Harvard Health Blog - November 4, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Coronavirus and COVID-19 Health Infectious diseases Source Type: blogs
FDA Determined Convalescent Plasma Is Safe, Leaves Decisions on Efficacy up to Clinicians/ Patients. That’s the Way It Should Always Be
Jeffrey A. SingerYesterday the Food and Drug Administration released a clinical memorandum giving Emergency Use Authorization for COVID-19 Convalescent Plasma (CCP) therapy, a previously unapproved biological product. Forseveral months clinicians treating severely ill COVID-19 patients have transfused plasma donated by convalescing COVID-19 patients, rich with the antibodies to the virus produced by their immune system, hoping that these same antibodies can help patients suffering from active infection. Early results have been promising but, as somecritics of the FDA decision have stated, more data is needed befo...
Source: Cato-at-liberty - August 24, 2020 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs
The Story of an American Mask Distributor
By SAURABH JHA
Seven weeks before President Trump declared COVID-19 a federal emergency heralding the economic lockdown, Jesse’s customers began cutting their orders. Jesse sells garments and cotton, imported predominantly from India, to wholesalers and retailers, big and small, in malls across the North East corridor. His business had a good January. December was like any December. But February was different. His customers, reassuring him that it wasn’t personal, were predicting a falling demand for their products because of COVID-19. They may be over reacting, but better shortage than glut, they felt.
J...
Source: The Health Care Blog - August 13, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy masks Pandemic Saurabh Jha Source Type: blogs
The trouble with magical thinking . . .
is that it doesn ' t work, by definition.That ' s why they call it magical. Now that Brazilian mini-Trump Jair Bolsonaro is sick with Covid-19 -- though still throwing in some magical thinking about hydroxychloroquine -- his months long dismissal of the virus as " just a little flu " and his continual urging that Brazilians simply ignore it looks, well, completely idiotic.The officially reported death toll from the virus in Brazil is over 66,000 but we know that is a gross understatement. Aerial photographs show mass graves, and we know that poor Brazilians have little access to health care and most certainly do not ...
Source: Stayin' Alive - July 7, 2020 Category: American Health Source Type: blogs
Covid-19 Reuters Q & A with William Haseltine
I live-tweeted a fascinating and perhaps rather depressing meeting with William Haseltine via a Reuters Newsmaker Broadcast. His talk was upbeat but the message does not offer a positive outlook unless we can collaborate internationally to identify, trace, and isolate and go back to early antivirals to treat people urgently. A vaccine will probably never be found, we must stay on top of this virus when we get communities under control. Moreover, we must recognise that another emergent pathogen could appear any time.
These are essentially my notes from Haseltines’s talk.
Might we ever achieve herd immunity?
There is n...
Source: David Bradley Sciencebase - Songs, Snaps, Science - May 20, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs
Covid-19 Reuters Newsmaker Broadcast with William Haseltine
I live-tweeted a fascinating and perhaps rather depressing meeting with William Haseltine via a Reuters Newsmaker Broadcast. His talk was upbeat but the message does not offer a positive outlook unless we can collaborate internationally to identify, trace, and isolate and go back to early antivirals to treat people urgently. A vaccine will probably never be found, we must stay on top of this virus when we get communities under control. Moreover, we must recognise that another emergent pathogen could appear any time.
These are essentially my notes from Haseltines’s talk.
Might we ever achieve herd immunity?
There is n...
Source: David Bradley Sciencebase - Songs, Snaps, Science - May 20, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs
Will the Uncertainties of COVID Science Resurrect Blogs?
Health news was popular before the pandemic. Now, almost all news is health news.
It’s not only a rapt audience contributing to the deluge of COVID19 news. Two other factors: 1) the availability of preprint servers, digital archives where a scientific paper can be published without formal peer-review and 2) the attention economy.
Attention is currency. Since the business model of both scientific journals, internet-based medical news sites and mainstream media is attention (citations, views), both groups are eager to publish all that is COVID.
The slew of COVID papers are outpacing the normal vetting process. ...
Source: Dr John M - May 8, 2020 Category: Cardiology Authors: Dr John Source Type: blogs
Can We Discuss Flatten-the-Curve in COVID19? My Eight Assertions
Conclusion:
I did not have a clear answer for my couple. But after thinking and writing about this question it seems that the most reasonable approach in this crisis is transparent information–no matter how stark. And, crucially, we must have space for public debate.
I hate this virus. I wish it never came. But we can make it worse by avoiding hard discussions on tradeoffs, the limits of modern medicine and risk.
JMM
P.S. I am very interested in your rebuttals to any of my assertions but will block vitriol and politicized nonsense.
Related posts:
The Debacle of Hydroxychloroquine and Azithromycin for ...
Source: Dr John M - May 4, 2020 Category: Cardiology Authors: Dr John Source Type: blogs
Keeping Kids Healthy in the Age of Coronavirus: Dr. Greene on The People s Pharmacy
Transcript
[00:00:00] Joe Graedon: I’m Joe Graedon.
[00:00:01] Terry Graedon: And I’m Terry Graedon. Welcome to this podcast of the People’s Pharmacy.
[00:00:06] Joe Graedon: You can find previous podcasts and more information on a range of health topics at PeoplesPharmacy.com.
[00:00:14] How’s your family holding up during the coronavirus pandemic? Isolation can be especially challenging for children.
[00:00:22] This is the People’s Pharmacy with Terry and Joe Graedon.
[00:00:33] Terry Graedon: Children appear less susceptible than older adults to serious complications of COVID-19...
Source: Conversations with Dr Greene - April 21, 2020 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog COVID COVID-19 Viral Infection Source Type: blogs
Keeping Kids Healthy in the Age of Coronavirus: Dr. Greene on The People ’ s Pharmacy
Transcript
[00:00:00] Joe Graedon: I’m Joe Graedon.
[00:00:01] Terry Graedon: And I’m Terry Graedon. Welcome to this podcast of the People’s Pharmacy.
[00:00:06] Joe Graedon: You can find previous podcasts and more information on a range of health topics at PeoplesPharmacy.com.
[00:00:14] How’s your family holding up during the coronavirus pandemic? Isolation can be especially challenging for children.
[00:00:22] This is the People’s Pharmacy with Terry and Joe Graedon.
[00:00:33] Terry Graedon: Children appear less susceptible than older adults to serious complications of COVID-19...
Source: Conversations with Dr Greene - April 21, 2020 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog COVID COVID-19 Viral Infection Source Type: blogs
COVID-19 Podcast: Mom Driven, Doctor Aligned & HeyMama Join Forces
Transcript
[00:00:00] Agatha: Hi! It’s Agatha Luczo. Welcome to “Mom Driven, Dr. Aligned”. Dr. Alan Greene and I were just on with the HeyMama Community doing a Q&A about COVID-19. Dr. Greene gave us such amazing advice and tips about how to deal with immunity health and how to take care of ourselves during this time. And some advice I haven’t heard anywhere else. I’m excited to bring all of the conversation to our family and friends.
[00:00:36] Dr. Greene: Wonderful to get to be with the HeyMama Community. I’ve gotten a bunch of questions already ...
Source: Conversations with Dr Greene - April 16, 2020 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Uncategorized COVID COVID-19 Parenting Source Type: blogs
Drugs for COVID-19: A Publishing Epidemic
As of April 9, PubMed listed 2,868 scientific publications which incorporate the word “COVID”. 323 of these (11.3%) were related to drugs under study for treatment of the disease. No fewer than thirty-one such drugs had been proposed since this pandemic first appeared on the planet four months earlier.
Graph 1 depicts the cumulative numbers of COVID-19 infection (per 100,000 global population) and introductions of relevant drugs into the Literature during February 14 to April 3. Note that both increased by a factor of approximately 16-fold during this period.
In a...
Source: GIDEON blog - April 12, 2020 Category: Databases & Libraries Authors: Uri Blackman Tags: Epidemiology Graphs Source Type: blogs
This treatment could save your life – COVID-19 and Convalescent Plasma Therapy
Ajay Kohli
Vinay Kohli
Chitra Chhabra Kohli
By CHITRA CHHABRA KOHLI MD, AJAY KOHLI MD, and VINAY KOHLI MD, MBA
With a doubling time of cases estimated between 3 days within the U.S. and about 6 days globally (at the time of this writing) COVID-19 is demonstrating its terrifying virulence as it spreads across the world.
What’s perhaps equally terrifying, if not more, is the absence of a known cure or treatment plan for COVID-19. While there has been a lot of attention focused on Hydroxychloroquine and Azithromycin, there has been debate on the scientific validity of these treatment options, either as thera...
Source: The Health Care Blog - March 30, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Patients Physicians Ajay Kohli Azithromycin convalescent plasma therapy coronavirus COVID-19 treatment hydroxychloroquine Pandemic Vinay Kohli Source Type: blogs
