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Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

" The Second Request " Podcast Episode Request: Spotting Anticompetitive Conduct in Pharma Supply Chain, with 46brooklyn
The Capitol Forum is what I suppose can be called a Washington, DC-based, center-left leaning investigative news organization. In 2017, the website " Talking Biz News " (which is apparently about the news business)https://talkingbiznews.com/media-moves/whats-behind-capitol-forum-and-its-growth-plans/ operated by Chris Roush, who ' s dean of the School of Communications at Quinnipiac University (a university which happens to be a few miles away from where I grew up, so it seemed legitimate to me) described The Capitol Forum this way: " Digging deep into the connection between business and government regulation. "Anyway, The...
Source: Scott's Web Log - April 12, 2023 Category: Endocrinology Tags: 2023 46Brooklyn Research Antonio Ciaccia drug prices laissez-faire antitrust enforcement Monopoly Problems The Capitol Forum The Second Request podcast Source Type: blogs

" The Second Request " Podcast Episode Recommendation: Spotting Anticompetitive Conduct in Pharma Supply Chain, with 46brooklyn
The Capitol Forum is what I suppose can be called a Washington, DC-based, center-left leaning investigative news organization. In 2017, the website " Talking Biz News " (which is apparently about the news business)https://talkingbiznews.com/media-moves/whats-behind-capitol-forum-and-its-growth-plans/ operated by Chris Roush, who ' s dean of the School of Communications at Quinnipiac University (a university which happens to be a few miles away from where I grew up, so it seemed legitimate to me) described The Capitol Forum this way: " Digging deep into the connection between business and government regulation. "Anyway, The...
Source: Scott's Web Log - April 12, 2023 Category: Endocrinology Tags: 2023 46Brooklyn Research Antonio Ciaccia drug prices laissez-faire antitrust enforcement Monopoly Problems The Capitol Forum The Second Request podcast Source Type: blogs

Fighting the Wrong (Culture) War
By KIM BELLARD News flash from the culture wars: they’re coming to take our gas stoves! Well, actually, “they” are not, but the kind of people who got alarmed about it are a threat to our health, and to theirs. The gas stove furor started with a Bloomberg News interview that Richard Trumka, Jr, a Consumer Product Safety Commission commissioner. “This is a hidden hazard,” he said. “Any option is on the table. Products that can’t be made safe can be banned.” He was referring to the well known but little acknowledged fact that gas stoves emit various pollutants, especially nitrogen dioxide. Last ye...
Source: The Health Care Blog - January 20, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Culture Wars Gas Stoves Kim Bellard Source Type: blogs

The college football fans that beat COVID and the experts that couldn ’t
BY ANISH KOKA The COVID pandemic was supposed to herald the end of the idea that a smaller government is a better government. The experts who desperately seek to be in charge of a sprawling bureaucratic state told us that it was only a powerful central authority that could do what was needed to safeguard individual liberties at a time when a highly contagious respiratory virus was spreading across the globe. New Zealand may have imposed draconian policies that did not even allow its own citizens to return, but scenes of cheering unmasked New Zealanders stood in sharp contrast to empty seats in American stadiums when ...
Source: The Health Care Blog - October 12, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: COVID-19 Health Policy College Football New Zealand Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
 September 08, 2022 Edition-----In the US we are seeing the outcomes of Climate Change really of and running with droughts and fires etc. Biden amped up the partisan divide with a fiery anti-Republican speech!In Russia the last leader of Soviet Russia died.In the UK we have a new PM while in Europe the energy crisis is just getting worse.In OZ we have survived the Jobs and Skills Summit with 36 prearranged outcomes. Stage management +++ in action. The GP crisis is not being addressed fully and worries regarding the Global Economy - esp. China - worsen.-----Major Issues.-----https://www.afr.com/work-and-careers/educati...
Source: Australian Health Information Technology - September 8, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Selfish Much?
By KIM BELLARD In a week where we’ve seen the bungled Afghan withdrawal, had Texas show us its contempt for all sorts of rights, watched wildfires ravage the west and Ida wreak havoc on a third of the country, and, of course, witnessed COVID-19 continue its resurgence, I managed to find an article that depressed me further.  Thank you, Aaron Carroll. Dr. Carroll – pediatrician, long-time contributor to The New York Times, and now Chief Health Officer of I.U. Health — wrote a startling piece in The Atlantic: We’ve Never Protected the Vulnerable.  He looks at the resistance to public health measur...
Source: The Health Care Blog - September 7, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy health equity Kim Bellard Source Type: blogs

Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 11th 2021
This study demonstrates the potential of a natural (o-Vanillin) and a synthetic (RG-7112) senolytic compounds to remove senescent IVD cells, decrease SASP factors release, reduce the inflammatory environment and enhance the IVD matrix production. Removal of senescent cells, using senolytics drugs, could lead to improved therapeutic interventions and ultimately decrease pain and a provide a better quality of life of patients living with intervertebral disc degeneration and low back pain. From Ying Ann Chiao of Oklahoma Medical Research Foundation: Mitochondrial dysfunction plays a central role in aging and cardiovasc...
Source: Fight Aging! - January 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Story of an American Mask Distributor
By SAURABH JHA Seven weeks before President Trump declared COVID-19 a federal emergency heralding the economic lockdown, Jesse’s customers began cutting their orders. Jesse sells garments and cotton, imported predominantly from India, to wholesalers and retailers, big and small, in malls across the North East corridor.  His business had a good January. December was like any December. But February was different.  His customers, reassuring him that it wasn’t personal, were predicting a falling demand for their products because of COVID-19. They may be over reacting, but better shortage than glut, they felt. J...
Source: The Health Care Blog - August 13, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy masks Pandemic Saurabh Jha Source Type: blogs

Post #50 School Reopening during the COVID-19 Pandemic
There is probably a no more emotionally charged topic of discussion currently than that of school reopening this fall. And for good reason - nearly everyone has a stake in it.Society is concerned because of the real risk of increased community spread.Teachers are concerned because of the COVID-19 risk to themselves and how the logistics of school will directly affect their livelihood and stress level as they have to constantly adjust to the barrage of changes and duties. Families are concerned because of the COVID-19 risk to their children and to those living at home. Not to mention, many depend on school to allow for...
Source: A Pediatrician's Blog - July 23, 2020 Category: Pediatrics Source Type: blogs

The Trump COVID Legacy: Bad Timing. Lots of Questions. Few Answers.
By MIKE MAGEE, MD What a strange irony. Trump decides, full-bravado, to challenge China to a trade war just months before China unwittingly hatches a virulent pandemic that collapses our deeply segmented health care system and our economy simultaneously. And rather than cry “Uncle”, our President then fires the WHO just as their experts are heading to China to attempt to unravel the mystery of COVID-19. With the ongoing, cascading catastrophe of Trump’s mishandling of COVID-19, it is easy to lose sight that the next pandemic (fueled by global warming, global trade, and human and animal migration) is just around...
Source: The Health Care Blog - July 16, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Politics Mike Magee Trump Source Type: blogs

The 2020 Pandemic Election
The 2020 US election will be vicious, with a nasty pandemonium following a nasty pandemic. By SAURABH JHA, MD When the COVID-19 pandemic is dissected in the 2020 presidential election debates, Donald Trump will be at a disadvantage. The coronavirus has killed over 100,000 Americans and maimed thousands more. The caveat is that deaths per capita, rather than total deaths, better measure national failure, and by that metric the US fares better than Belgium, Italy and the United Kingdom. New York City owns a disproportionate share of the deaths, but this hyperconnected megapolis is an outlier whose misfortunes ...
Source: The Health Care Blog - July 15, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Politics Saurabh Jha Source Type: blogs