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Total 13 results found since Jan 2013.

Fight Aging! Newsletter, December 6th 2021
In this study, they found these drugs can kill senescent cells from cultures of human fat tissue. The tissue was donated by individuals with obesity who were known to have metabolic troubles. Without treatment, the human fat tissues induced metabolic problems in immune-deficient mice. After treatment with dasatinib and quercetin, the harmful effects of the fat tissue were almost eliminated. Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2...
Source: Fight Aging! - December 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 10th 2020
This study aimed to characterize the role of BDNF in age-related microglial activation. Initially, we found that degrees of microglial activation were especially evident in the substantia nigra (SN) across different brain regions of aged mice. The levels of BDNF and TrkB in microglia decreased with age and negatively correlated with their activation statuses in mice during aging. Interestingly, aging-related microglial activation could be reversed by chronic, subcutaneous perfusion of BDNF. Peripheral lipopolysaccharide (LPS) injection-induced microglial activation could be reduced by local supplement of BDNF, while shTrkB...
Source: Fight Aging! - August 9, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Hospital Outpatient Visits Drop for First Time; Long History of Similar Inpatient Declines
It is well documented that hospital inpatient admissions have been declining for the past thirty years (see:The Case of the"Disappearing Hospital Beds"; Implications for Pathologists;Inpatient Admissions Decreasing; Implications for Hospital-Based Labs). Now comes news of a decline in outpatient visits (see:Outpatient Visits to Hospitals Decline Year-to-Year for First Time in 35 Years) Below is an excerpt from the article:Thanks to the popularity of urgent care clinics and other non-hospital-based ambulatory care providers, the year-over-year growth in the number of hospital outpatient visits has been on th...
Source: Lab Soft News - February 25, 2020 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Cost of Healthcare Health Wearable Healthcare Delivery Healthcare Innovations Medical Consumerism Quality of Care Telemedicine Source Type: blogs

Fight Aging! Newsletter, December 23rd 2019
In this study, by adenovirus-mediated delivery and inducible transgenic mouse models, we demonstrate the proliferation of both HCs and SCs by combined Notch1 and Myc activation in in vitro and in vivo inner ear adult mouse models. These proliferating mature SCs and HCs maintain their respective identities. Moreover, when presented with HC induction signals, reprogrammed adult SCs transdifferentiate into HC-like cells both in vitro and in vivo. Finally, our data suggest that regenerated HC-like cells likely possess functional transduction channels and are able to form connections with adult auditory neurons. Epige...
Source: Fight Aging! - December 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How Does Medical Virtual Reality Make Healthcare More Pleasant?
Medical virtual reality goes entirely against conventional beliefs about technology making healthcare less human, less empathetic and less caring. Virtual reality teaches empathy to med students, makes vaccination for children more sufferable, helps get rid of fears by treating phobias, relieves chronic pain or fulfills the last wishes of the dying. The many faces of medical virtual reality Although the use of virtual reality in healthcare is not widespread yet, the technology holds great promise. Goldman Sachs estimated in its 2016 report that 8 million physicians and medical technicians could make use of augmented reali...
Source: The Medical Futurist - April 24, 2018 Category: Information Technology Authors: nora Tags: Future of Medicine Virtual Reality in Medicine chronic pain empathy Healthcare pain management pediatrics psychology trauma vaccination VR Source Type: blogs

Demand Congress to go on Medicare at the age of 65
Born in Canada, our mother came to the United States after World War II and blended into the Greatest Generation. Raising a family in the second half of the 20th century saw her contribute to a thriving American society then maintain retirement health on Medicare. But in her early 90s, this tranquility was threatened when her HMO hospital tried to kill her. She went to the emergency room with symptoms of the stomach flu, and ended up rapidly placed on palliative care with an erroneous diagnosis of end-stage liver cancer. Fortunately, after a long ordeal and because of our medical background, we thwarted hospital personnel ...
Source: Kevin, M.D. - Medical Weblog - August 11, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/gene-uzawa-dorio" rel="tag" > Gene Uzawa Dorio, MD < /a > Tags: Policy Geriatrics Source Type: blogs

Fight Aging! Newsletter, May 2nd 2016
This study is the first CAR T-cell trial to infuse patients with an even mixture of two types of T cells (helper and killer cells, which work together to kill cancer). With the assurance that each patient gets the same mixture of cells, the researchers were able to come to conclusions about the effects of administering different doses of cells. In 27 of 29 participants whose responses were evaluated a few weeks after the infusion, a high-sensitivity test could detect no trace of their cancer in their bone marrow. The CAR T cells eliminated cancers anywhere in the body they appeared. Of the two participants who did n...
Source: Fight Aging! - May 1, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Joint Commission Mandates Armband to Identify Patients With Too Many Armbands.
Oakbrook Terrace, IL --  Hospitals are up in arms again after The Joint Commission (TJC) on Monday started requiring all patients with too many armbands  to be flagged with an armband for having too many armbands. Mark Chassin, President and Chief Executive Officer of TJC, applauded his organization for taking  action against his organization's failed policies."I'm proud The Joint Commission is finally  taking a stand against The Joint Commission for continuing to ignore all the unintended consequences of their regulations," said Dr. Chassin.Doctors and nurses have been telling authorities for years tha...
Source: The Happy Hospitalist - May 25, 2015 Category: Internal Medicine Authors: Tamer Mahrous Source Type: blogs

Building a Better Mortality Prediction Rule
You will often hear the lament from people within and outside of the hospice and palliative care fields, that doctors are pretty bad at making effective prognostication. Patients and families frequently search for a predictable road map to understand the course they are likely on, and even when they cede the understandable uncertainty to the physician, the doctors will often reply with an unhelpful retorts like, “I don’t know what may happen. There is only one person who does.” I doubt all of those physicians are referring to Dr. Mark Cowen, but they may want to take notice of what he and his colleagues at St. Joseph...
Source: Pallimed: A Hospice and Palliative Medicine Blog - August 22, 2014 Category: Palliative Carer Workers Authors: Christian Sinclair Source Type: blogs

Research and Reviews in the Fastlane 038
This study, however, has major flaws and biases that question the validity of their conclusions. Only 19% of centers that were contacted agreed to contribute data to the Consortium. Additionally, the researchers do not assess the quality of the studies included in their meta-analysis. Regardless, observational data should not be used to trump the RCT data included in the recent, Cochrane review. Finally, Roche pharmaceuticals was a major sponsor of this research team. The accompanying editorial is a must-read. Recommended by: Anand Swaminathan Infection Control, Hand hygiene D’Egidio G et al. A study of the ...
Source: Life in the Fast Lane - July 10, 2014 Category: Emergency Medicine Authors: Nudrat Rashid Tags: Anaesthetics Cardiology Emergency Medicine Featured Infectious Disease Intensive Care Neurology Palliative care R&R in the FASTLANE Radiology Resuscitation Trauma critical care literature recommendations research and reviews Source Type: blogs

Weekly Roundup – December 6, 2013
Happy Friday! It has been a while since the roundup ran on a Friday; we were trying different days to see what our fabulous readers preferred. If you have a preference let us know. Does hormone replacement therapy help aging women’s moods and mental agility? The Los Angeles Times ran an article on a study that says it is not helpful, read the article for more on this study as well as a few others that are in the works. A study recently published in the New England Journal of Medicine found that vaccination programs for children have prevented more than 100 million cases of serious contagious disease in the United States ...
Source: Disruptive Women in Health Care - December 6, 2013 Category: Health Medicine and Bioethics Commentators Authors: dw at disruptivewomen.net Tags: Roundup Columbia University Columbia University Mailman School of Public Health Kaiser Health News Los Angeles Times new york times Palliative care USA Today usatoday Source Type: blogs

Twerking Disease: The Definitive Medical Resource For Doctors.
This study was published in Time magazine so it must be true.  In addition, the story was picked up by 95.8 THE BONE and was described by a self proclaimed expert twerker jockey between songs about booty slappin' and G-thangs.      EXERCISE Studies have shown most folks watching Richard Simmons in "Twerking to the Oldies" have been cured of their twerking addiction.      MIRROR THERAPY Consider buying a full length wall mirror for full therapeutic effect.  Alternatively, take a video of yourself twerking while checking yourself out in a mirror, put it on YouTube and let ever...
Source: The Happy Hospitalist - September 7, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs

Why doctors and nurses should be required to have flu shots
I was recently speaking to the clinical leaders of a mid-sized hospital, and a senior administrator posed the question, “should we require our doctors and nurses to get flu shots?” The answer, I said, is yes, and it isn’t just to prevent the flu. It’s to get into the habit of making our folks do the right thing when it comes to patient safety.Continue reading ... Manage your online reputation: A complete social media guide. Read the book by KevinMD.
Source: Kevin, M.D. - Medical Weblog - February 5, 2013 Category: Family Physicians Tags: Physician Infectious disease Palliative care Source Type: blogs