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Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery.
CONCLUSION: In pregnancies complicated by gastroschisis, and with no other known major indications, birth at early term or later term gestation, when compared with delivery before 37 weeks of gestation, is associated with improved perinatal outcomes and lower medical costs. LEVEL OF EVIDENCE: : II. PMID: 25162254 [PubMed - in process]
Source: Obstetrics and Gynecology - August 30, 2014 Category: OBGYN Authors: Cain MA, Salemi JL, Paul Tanner J, Mogos MF, Kirby RS, Whiteman VE, Salihu HM Tags: Obstet Gynecol Source Type: research

Timing of Elective Delivery in Gastroschisis: A Decision and Cost Effectiveness Analysis.
CONCLUSIONS: In pregnancies complicated by gastroschisis, the most cost-effective timing of delivery is 38 weeks. Few additional cases of RDS are caused for every 1 stillbirth or death within 1 year prevented with delivery at 37-38 weeks. PMID: 25377308 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - November 6, 2014 Category: Radiology Authors: Harper LM, Goetzinger KR, Biggio JR, Macones GA Tags: Ultrasound Obstet Gynecol Source Type: research

Peripartum and neonatal outcomes of small‐for‐gestational‐age infants with gastroschisis
ConclusionAmong infants with gastroschisis, SGA at birth is associated with a 4‐fold increase in odds for prolonged LOS, independent of GA. © 2015 John Wiley & Sons, Ltd.
Source: Prenatal Diagnosis - January 22, 2015 Category: Perinatology & Neonatology Authors: Anna I. Girsen, Samantha Do, Alexis S. Davis, Susan R. Hintz, Arti K. Desai, Trina Mansour, T. Allen Merritt, Bryan T. Oshiro, Yasser Y. El‐Sayed, Yair J. Blumenfeld Tags: Original Article Source Type: research

Fetal Growth Pattern and Prediction of Low Birth Weight in Gastroschisis
Objectives: To examine growth patterns and predictions of low birth weight in gastroschisis fetuses. Methods: This is a retrospective study of isolated fetal gastroschisis before week 24. Ultrasound fetal biometric parameters - head circumference (HC), abdominal circumference (AC), femur length, HC/AC ratio and estimated fetal weight (EFW) - were plotted against normal growth charts. The percentage difference in mean values between normal and gastroschisis fetuses was determined. The growth deficit for each ultrasound parameter was calculated for the fetuses with 1 examination in each designated period (period I: weeks 20-...
Source: Fetal Diagnosis and Therapy - February 3, 2015 Category: Perinatology & Neonatology Source Type: research

Pre‐ and postnatal modifications in parental mental representations in three cases of fetal gastroschisis diagnosed during pregnancy
ABSTRACT The aim of this study was to identify possible effects of gastroschisis on parents’ intrapsychic dynamics by applying an observational clinical approach. More specifically, we intend to (a) evaluate the representational style of parents informed about the diagnosis of fetal gastroschisis during pregnancy using the Interview of Maternal Representations During Pregnancy and the Interview of Paternal Representations During Pregnancy (M. Ammaniti, C. Candelori, M. Pola, & R. Tambelli, ) and (b) observe whether the baby's birth influences the parents’ representational styles through the application of the same ...
Source: Infant Mental Health Journal - September 1, 2015 Category: Child Development Authors: ANTONELLA TRIPANI, SANDRA PELLIZZONI, ROSELLA GIULIANI, STEFANO BEMBICH, ANDREA CLARICI, ISABELLA LONCIARI, MASSIMO AMMANITI Tags: ARTICLE Source Type: research

Sonographic Detection and Clinical Importance of Growth Restriction in Pregnancies With Gastroschisis
Conclusions— Sonography reliably identified SGA neonates with gastroschisis in our series, and its utility improved with advancing gestation. Apart from delayed closure of the defect, a low birth weight percentile was not associated with an increased risk of morbidity or mortality in the immediate neonatal period.
Source: Journal of Ultrasound in Medicine - November 25, 2015 Category: Radiology Authors: Nelson, D. B., Martin, R., Twickler, D. M., Santiago-Munoz, P. C., McIntire, D. D., Dashe, J. S. Tags: Original Research Source Type: research

Successful management of discordant gastroschisis in monochorionic diamniotic twin: a case report.
CONCLUSION: This report expands successful management of discordant gastroschisis in MCDA twins. Early diagnosis, intensive prenatal care, and multidisciplinary consultation are recommended in management of discordant gastroschisis in MCDA twin. PMID: 26411235 [PubMed - indexed for MEDLINE]
Source: Clinical and Experimental Obstetrics and Gynecology - December 20, 2015 Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research

Nutritional management and postoperative prognosis of newborns submitted to primary surgical repair of gastroschisis.
CONCLUSION: Early start of enteral feeding and small, gradual increase of volume can shorten the use of parenteral nutrition. This management strategy contributes to reduce the incidence of infection and length of hospital stay of newborns with gastroschisis. PMID: 26844392 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - February 1, 2016 Category: Pediatrics Authors: Miranda da Silva Alves F, Miranda ME, Aguiar MJ, Bouzada MC Tags: J Pediatr (Rio J) Source Type: research

Management of gastroschisis
Purpose of review: The diagnosis and treatment of gastroschisis spans the perinatal disciplines of maternal fetal medicine, neonatology, and pediatric surgery. Since gastroschisis is one of the commonest and costliest structural birth defects treated in neonatal ICUs, a comprehensive review of its epidemiology, prenatal diagnosis, postnatal treatment, and short and long-term outcomes is both timely and relevant. Recent findings: The incidence of gastroschisis has increased dramatically over the past 20 years, leading to a renewed interest in causation. The widespread availability of maternal screening and ultrasound resul...
Source: Current Opinion in Pediatrics - May 3, 2016 Category: Pediatrics Tags: SURGERY: Edited by Brad W. Warner Source Type: research

Gene variants as risk factors for gastroschisis
In a population‐based case‐control study in California of 228 infants, we investigated 75 genetic variants in 20 genes and risk of gastroschisis with regard to maternal age, race/ethnicity, vitamin use, and smoking exposure. We hypothesized that genes related to vascular compromise may interact with environmental factors to affect the risk of gastroschisis. Haplotypes were constructed for 75 gene variants using the HaploView program. Risk for gastroschisis associated with each gene variant was calculated for both the homozygotes and the heterozygotes, with the homozygous wildtypes as the referent. Risks were estimated ...
Source: American Journal of Medical Genetics Part A - September 11, 2016 Category: Genetics & Stem Cells Authors: Amy M. Padula, Wei Yang, Kathleen Schultz, Lauren Tom, Bin Lin, Suzan L. Carmichael, Edward J. Lammer, Gary M. Shaw Tags: Original Article Source Type: research

Excessive Postoperative Fluid Administration in Infants with Gastroschisis.
Abstract Careful fluid management is a cornerstone of neonatology because the cardiovascular, respiratory, and gastrointestinal systems in the newborn are sensitive to overhydration. Fluid management in gastroschisis is complicated by insensible fluid loss and postoperative third-space fluid shifts. Study of perioperative fluid management in gastroschisis is limited and has not undergone careful scrutiny. We reviewed perioperative fluid administration and urine output in all infants with gastroschisis over a 5-year period. Data included whether the patient underwent primary closure or staged repair, weight, and ev...
Source: The American Surgeon - July 31, 2016 Category: Surgery Authors: Bonasso PC, Lucke-Wold B, Hobbs GR, Vaughan RA, Shorter NA, Nakayama DK Tags: Am Surg Source Type: research

Maternal Antibodies to Herpes Virus Antigens and Risk of Gastroschisis in Offspring.
Abstract Gastroschisis risk is highest in offspring of young women and is increasing in prevalence, suggesting that exposures that are increasingly common among younger females may be causal. Some infections by viruses in the herpes family are more common in the earlier childbearing years and have been increasing in prevalence over time. Data from the Finnish Maternity Cohort were linked to Finnish malformation and birth registers (1987-2012) for this study, a nested case-control study of mothers of offspring with gastroschisis and age-matched controls. Maternal antibody responses in early pregnancy (mean gestatio...
Source: Am J Epidemiol - November 16, 2016 Category: Epidemiology Authors: Werler MM, Parker SE, Hedman K, Gissler M, Ritvanen A, Surcel HM Tags: Am J Epidemiol Source Type: research

Neurodevelopment and Health-Related Quality of Life in Infants Born with Gastroschisis: A 6-Year Retrospective French Study
Conclusion Our analyses confirm the idea that cases of complex gastroschisis and preterm delivery may lead to poorer outcome. Such hindsight (40 months in mean) allowed for an interesting assessment of development long after the patient's initial hospitalization and to confirm these results, a standardized neuropsychological evaluation of patients should be done when at least 6 years old. An accurate assessment of the social environment and its impact on the development and QoL of children will be fundamental to avoid selection bias. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of ...
Source: European Journal of Pediatric Surgery - December 7, 2016 Category: Surgery Authors: Tosello, Barthelemy Zahed, Meriem Guimond, Floriane Baumstarck, Karine Faure, Alice Michel, Fabrice Claris, Olivier Massardier, Jerome Gire, Catherine Merrot, Thierry Tags: Original Article Source Type: research

Quality of life in patients with gastroschisis is comparable with the general population: A questionnaire survey.
CONCLUSION: The study has shown that the majority of patients after operation of gastroschisis have a very good quality of life without limitation in comparison with the general population. The presented anthropometric data confirm that the development of patients with gastroschisis is favourable. PMID: 27982137 [PubMed - as supplied by publisher]
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - December 17, 2016 Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research

Early Commencement of Enteral Feeds in Gastroschisis: A Systematic Review of Literature
Conclusions Early CEF may be associated with early attainment of FEF in gastroschisis. RCTs comparing early versus delayed CEF are needed urgently. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: European Journal of Pediatric Surgery - January 22, 2017 Category: Surgery Authors: Dama, Madhuri Rao, Uday Gollow, Ian Bulsara, Max Rao, Shripada Tags: Original Article Source Type: research