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Insights into the medical management of gastrointestinal stromal tumours: lessons learnt from a dedicated gastrointestinal stromal tumour clinic in North India
CONCLUSION: Our study is one of the largest comprehensive series describing the clinical and mutational profile of GIST from India. The mutation testing rates at primary care centres continue to be low. Despite the hurdles, a large percentage of our patients underwent molecular testing, aiding in therapeutic decision-making.PMID:36816783 | PMC:PMC9937073 | DOI:10.3332/ecancer.2023.1497
Source: Ecancermedicalscience - February 23, 2023 Category: Cancer & Oncology Authors: Annie Kanchan Baa Sameer Rastogi Sanal Fernandes Shakti Shrivastava Rajni Yadav Adarsh Barwad Shamim A Shamim Nihar Ranjan Dash Source Type: research
Clinicopathological, immunohistochemical, molecular-genetic and risk profiles of gastrointestinal stromal tumors in a cohort of Sudanese patients
Conclusions: Sudanese patients with GIST tend to present late. Nearly half of them correspond to the malignant/high-risk category. The frequency of KIT mutations (79.31%) is in line with the literature.Keywords: Gastrointestinal stromal tumour; GIST; risk stratification; malignant behaviour; risk assessment; tumour rupture; metastasis; Imatinib; genotyping; KIT; DOG1.
Source: African Health Sciences - April 11, 2023 Category: African Health Authors: Nazik Elmalaika Husain, Ihsan Mohamed Osman, Ahmed Khalid, Ali Abdel Satir, Robert Stoehr, Abbas Agaimy Source Type: research
Insights into the medical management of gastrointestinal stromal tumours: lessons learnt from a dedicated gastrointestinal stromal tumour clinic in North India
CONCLUSION: Our study is one of the largest comprehensive series describing the clinical and mutational profile of GIST from India. The mutation testing rates at primary care centres continue to be low. Despite the hurdles, a large percentage of our patients underwent molecular testing, aiding in therapeutic decision-making.PMID:36816783 | PMC:PMC9937073 | DOI:10.3332/ecancer.2023.1497
Source: Ecancermedicalscience - February 23, 2023 Category: Cancer & Oncology Authors: Annie Kanchan Baa Sameer Rastogi Sanal Fernandes Shakti Shrivastava Rajni Yadav Adarsh Barwad Shamim A Shamim Nihar Ranjan Dash Source Type: research
