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Drug: Aspirin

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Paranoia is self-defeating. But you can change your mind about vaccinations
Forgoing vaccinations ‘just in case’ isn’t based on an assessment of the facts; it’s seeing facts that aren’t thereWhen I was in college in the early 1990s and eating more hallucinogenic mushrooms than probably advisable, I developed a theory that the United States government was engaged in a mind-control campaign through medicines approved by the Federal Drug Administration. I can’t tell you why, exactly – Brave New World? The Illuminatus Trilogy? Too many sci-fi movies? I just don’t know. The Matrix hadn’t even come out yet. But I stopped taking medicines – even just aspirin – and started treating a...
Source: Guardian Unlimited Science - November 18, 2014 Category: Science Authors: Dave Bry Tags: Vaccines and immunisation Psychology Health Source Type: news

A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

Janssen Submits New Drug Application to U.S. FDA for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, June 23, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the use of XARELTO® (rivaroxaban) in pediatric patients. The NDA seeks two pediatric indications: treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients aged birth to less than 18 years of age after at least five days of initial parenteral anticoagulant treatment; and thromboprophylaxis (prevention of blood clots) in patients aged 2 years and older with congenita...
Source: Johnson and Johnson - June 23, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

FDA Approves Two New Indications for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, Dec. 20, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved two pediatric indications for XARELTO® (rivaroxaban): the treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients from birth to less than 18 years after at least five days of initial parenteral (injected or intravenous) anticoagulant treatment; and thromboprophylaxis (prevention of blood clots and blood-clot related events) in children aged two years and older with congenital heart disease who have...
Source: Johnson and Johnson - December 21, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Data from New VOYAGER PAD Analyses at ACC.22 Reinforce Benefit of XARELTO ® (rivaroxaban) Plus Aspirin in Patients with Peripheral Artery Disease (PAD) and Various Co-Morbid Conditions
RARITAN, N.J., April 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from new analyses from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefit of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) in reducing severe vascular events in patients with PAD after lower-extremity revascularization (LER), a procedure that restores blood flow to the legs. Data from the two analyses demonstrate the role that the XARELTO® vascular dose plays in PAD patients with and without chronic kidney disease (CKD) and in PAD patients with and ...
Source: Johnson and Johnson - April 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

School Children and Their Medications - Making...
If your child needs to take medicine at school - from prescription drugs to aspirin - you need to know the rules and what you can do to help prevent medication mistakes.
Source: About.com Bipolar Disorder - September 8, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Hypertension care in Aseer region, Saudi Arabia: Barriers and solutions.
This study revealed that HTN patients received insufficient care, which could be attributed to many different barriers. In order to improve the quality of HTN care for HTN, these barriers should be overcome by implementation of the recommendations. PMID: 25394461 [PubMed - in process]
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2014 Category: Urology & Nephrology Authors: Al-Saleem SA, Al-Shahrani A, Al-Khaldi YM Tags: Saudi J Kidney Dis Transpl Source Type: research

Views and preferences of medical professionals and pregnant women about a novel primary prevention intervention for hypertensive disorders of pregnancy: a qualitative study
This study aimed to explore the acceptability, views and preferences of pregnant w...
Source: Reproductive Health - May 2, 2019 Category: OBGYN Authors: A. Vestering, M. N. Bekker, D. E. Grobbee, R. van der Graaf, A. Franx, N. M. T. Crombag and J. L. Browne Tags: Research Source Type: research

Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages
Interactions of inflammatory cells with pancreatic cancer cells play crucial roles in pancreatic cancer, however the dynamic changes of inflammatory cell populations in pancreatic cancerogensis and after chemo...
Source: Journal of Experimental and Clinical Cancer Research - February 16, 2016 Category: Cancer & Oncology Authors: Qiaofei Liu, Yuan Li, Zheyu Niu, Yi Zong, Mengyi Wang, Lutian Yao, Zhaohui Lu, Quan Liao and Yupei Zhao Source Type: research

Feces and liver tissue metabonomics studies on the regulatory effect of aspirin eugenol eater in hyperlipidemic rats
Based on the pro-drug principle, aspirin and eugenol were esterified to synthesize aspirin eugenol ester (AEE). The anti-hyperlipidemia effect of aspirin eugenol ester has been confirmed in hyperlipidemic rat ...
Source: Lipids in Health and Disease - December 11, 2017 Category: Lipidology Authors: Ning Ma, Xiwang Liu, Xiaojun Kong, Shihong Li, Zenghua Jiao, Zhe Qin, Pengcheng Dong, Yajun Yang and Jianyong Li Tags: Research Source Type: research

Meta-analysis on the Effect of Aspirin Use for Prevention of Preeclampsia on Placental Abruption and Antepartum Hemorrhage
(Abstracted from Am J Obstet Gynecol 2018;218:483–489) Impaired placentation in the first 16 weeks of pregnancy is associated with increased risk of subsequent development of preeclampsia, birth of small-for-gestational-age (SGA) neonates, and placental abruption. Previous studies reported that prophylactic use of aspirin reduces the risk of preeclampsia and SGA neonates with no significant effect on placental abruption.
Source: Obstetrical and Gynecological Survey - October 1, 2018 Category: OBGYN Tags: OBSTETRICS: PRECONCEPTION AND PRENATAL CARE Source Type: research

Authors' reply re: Association of intrauterine exposure to aspirin and blood pressure at 7  years of age: a secondary analysis.
Authors' reply re: Association of intrauterine exposure to aspirin and blood pressure at 7 years of age: a secondary analysis. BJOG. 2019 Jul 16;: Authors: Chen Y, Zhao D, Wang B, Zhu J, Zhang J, Zhang Y PMID: 31313485 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - July 15, 2019 Category: OBGYN Authors: Authors' reply re: Association of intrauterine exposure to aspirin and blood pressure at 7 years of age: a secondary analysis. Tags: BJOG Source Type: research

Early prediction of preeclampsia and small-for-gestational-age via multi-marker model in Chinese pregnancies: a prospective screening study
Recent evidence suggests early screening of preeclampsia and small-for-gestational-age (SGA) would benefit pregnancies followed by subsequent prophylactic use of aspirin. Multi-marker models have shown capabil...
Source: BMC Pregnancy and Childbirth - August 19, 2019 Category: OBGYN Authors: Jing Zhang, Luhao Han, Wei Li, Qiaobin Chen, Jie Lei, Min Long, Weibin Yang, Wenya Li, Lizhen Zeng and Sifan Zeng Tags: Research article Source Type: research

Aspirin inhibits RANKL-induced osteoclast differentiation in dendritic cells by suppressing NF- κB and NFATc1 activation
Aspirin has been demonstrated to promote osteoblast-mediated bone formation and inhibit osteoclast (OC)-mediated bone resorption. However, it remains unclear whether aspirin influences other immune cells durin...
Source: Stem Cell Research and Therapy - December 5, 2019 Category: Stem Cells Authors: Lili Wu, Zhenhua Luo, Yitong Liu, Lu Jia, Yiyang Jiang, Juan Du, Lijia Guo, Yuxing Bai and Yi Liu Tags: Research Source Type: research

Effect of low salicylate diet on clinical and inflammatory markers in patients with aspirin exacerbated respiratory disease – a randomized crossover trial
Aspirin-exacerbated respiratory disease (AERD) is characterized by eosinophilic rhinosinusitis, nasal polyposis, and bronchial asthma, along with the onset of respiratory reactions after the ingestion of nonst...
Source: Journal of Otolaryngology - Head and Neck Surgery - April 23, 2021 Category: ENT & OMF Authors: Leigh J. Sowerby, Krupal B. Patel, Crystal Schmerk, Brian W. Rotenberg, Taciano Rocha and Doron D. Sommer Tags: Original research article Source Type: research