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Cancers, Vol. 13, Pages 1654: Perceptions of Chinese Patients Treated for Gynaecological Cancer about Sexual Health and Sexual Information Provided by Healthcare Professionals: A Qualitative Study
This study aimed to examine the perceptions of Chinese patients treated for GC regarding the effects of cancer treatment on their sexual function and femininity, their relationships with their partners, and the adequacy of the sexual information received from healthcare professionals during treatment. Individual, semi-structured interviews were conducted with 21 Chinese patients treated for GC, collecting data on their perceptions regarding the effects of cancer treatment on their sexual lives, femininity, and relationships with partners; and their views about the quality of sexuality care received. Data were analysed usin...
Source: Cancers - April 1, 2021 Category: Cancer & Oncology Authors: Ka Ming Chow Carmen W.H. Chan Bernard M.H. Law Tags: Article Source Type: research
Cancers, Vol. 14, Pages 1534: Who Knows? Information Received, and Knowledge about, Cancer, Treatment and Late Effects in a National Cohort of Long-Term Childhood, Adolescent and Young Adult Cancer Survivors
Conclusions: Knowledge of cancer history and risks of late effects is essential for effective self-management, yet significant information and knowledge gaps were reported in this population-based sample of long-term CAYACS. Systematic approaches to making (up-to-date) information available to long-term survivors are needed to ensure that information does not get lost in medical and life transitions.
Source: Cancers - March 16, 2022 Category: Cancer & Oncology Authors: Micol E. Gianinazzi Cecilie E. Kiserud Ellen Ruud Hanne C. Lie Tags: Article Source Type: research
Cancers, Vol. 14, Pages 4959: The Good, the Bad and the New about Uric Acid in Cancer
zia Tozzi
Uric acid is the final product of purine catabolism in man and apes. The serum concentration of uric acid is sex-, age- and diet-dependent and is maintained close to its maximal solubility, indicating that it plays some important role. Indeed, it has been demonstrated that, at physiological concentrations, uric acid is a powerful antioxidant, while at high intracellular concentrations, it is a pro-oxidant molecule. In this review, we describe the possible causes of uric acid accumulation or depletion and some of the metabolic and regulatory pathways it may impact. Particular attention has been given to fructo...
Source: Cancers - October 10, 2022 Category: Cancer & Oncology Authors: Simone Allegrini Mercedes Garcia-Gil Rossana Pesi Marcella Camici Maria Grazia Tozzi Tags: Review Source Type: research
Cancers, Vol. 15, Pages 347: FOXP3 Isoforms Expression in Cervical Cancer: Evidence about the Cancer-Related Properties of FOXP3 & Delta;2 & Delta;7 in Keratinocytes
Cancers, Vol. 15, Pages 347: FOXP3 Isoforms Expression in Cervical Cancer: Evidence about the Cancer-Related Properties of FOXP3Δ2Δ7 in Keratinocytes
Cancers doi: 10.3390/cancers15020347
Authors:
Natalia Garcia-Becerra
Marco Ulises Aguila-Estrada
Luis Arturo Palafox-Mariscal
Georgina Hernandez-Flores
Adriana Aguilar-Lemarroy
Luis Felipe Jave-Suarez
Cervical cancer (CC) is the fourth most common type of cancer among women; the main predisposing factor is persistent infection by high-risk human papillomavirus (hr-HPV), mainly the 16 or 18 genotypes. Both hr-HPVs are known to manipulate t...
Source: Cancers - January 5, 2023 Category: Cancer & Oncology Authors: Natalia Garcia-Becerra Marco Ulises Aguila-Estrada Luis Arturo Palafox-Mariscal Georgina Hernandez-Flores Adriana Aguilar-Lemarroy Luis Felipe Jave-Suarez Tags: Article Source Type: research
Cancers, Vol. 15, Pages 4123: Effectiveness of Therapeutic Education in Patients with Cancer Pain: Systematic Review and Meta-Analysis
Conclusions: This review demonstrates that pain education in patients with cancer pain may produce effects such as decreased pain intensity and catastrophism. Knowledge about pain also seems to increase. However, no benefit was reported for patients’ overall quality of life. Therefore, more research is needed to clarify the effects of these interventions on the oncology population.
Source: Cancers - August 16, 2023 Category: Cancer & Oncology Authors: Ana Mar ía González-Martín Iv án Aguilera-García Yolanda Castellote-Caballero Yulieth Rivas-Campo Antonio Bernal-Su árez Agust ín Aibar-Almazán Tags: Systematic Review Source Type: research
Cancers, Vol. 12, Pages 2070: Risk Prediction and New Prophylaxis Strategies for Thromboembolism in Cancer
Labianca
In the general population, the incidence of thromboembolic events is 117 cases/100,000 inhabitants/year, while in cancer patient incidence, it is four-fold higher, especially in patients who receive chemotherapy and who are affected by pancreatic, lung or gastric cancer. At the basis of venous thromboembolism (VTE) there is the so-called Virchow triad, but tumor cells can activate coagulation pathway by various direct and indirect mechanisms, and chemotherapy can contribute to VTE onset. For these reasons, several studies were conducted in order to assess efficacy and safety of the use of anticoagulant therap...
Source: Cancers - July 26, 2020 Category: Cancer & Oncology Authors: Alice Labianca Tommaso Bosetti Alice Indini Giorgia Negrini Roberto Francesco Labianca Tags: Review Source Type: research
Cancers, Vol. 12, Pages 3000: Perceived Cognitive Impairment in Breast Cancer Survivors and Its Relationships with Psychological Factors
j
Marie Lange
Cognitive complaints are common adverse effects in cancer patients. Identifying subjects at risk could make it possible to limit their impact. We aimed to explore the relationship between current cognitive complaints and demographic and psychological factors in a group of breast cancer survivors. Through an online survey, cancer survivors reported current cognitive complaints using the FACT-Cog questionnaire (Perceived Cognitive Impairment) and answered questions about their demographics, lifestyle and cancer-related characteristics. Anxiety, depression, fatigue and post-traumatic stress symptoms were a...
Source: Cancers - October 16, 2020 Category: Cancer & Oncology Authors: Cl émence Boscher Florence Joly B énédicte Clarisse Xavier Humbert Jean-Michel Grellard Giulia Binarelli Laure Tron Idlir Licaj Marie Lange Tags: Article Source Type: research
Cancers, Vol. 13, Pages 3490: Current Status and Future Perspectives about Molecular Biomarkers of Nasopharyngeal Carcinoma
uen Cheah
Nasopharyngeal carcinoma (NPC) is an epithelial malignancy that shows a remarkable ethnic and geographical distribution. It is one of the major public health problems in some countries, especially Southern China and Southeast Asia, but rare in most Western countries. Multifactorial interactions such as Epstein–Barr virus infection, individual’s genetic susceptibility, as well as environmental and dietary factors may facilitate the pathogenesis of this malignancy. Late presentation and the complex nature of the disease have led it to become a major cause of mortality. Therefore, an effective, sensitive, an...
Source: Cancers - July 12, 2021 Category: Cancer & Oncology Authors: Pui Yan Siak Alan Soo-Beng Khoo Chee Onn Leong Boon-Peng Hoh Shiau-Chuen Cheah Tags: Review Source Type: research
Cancers, Vol. 14, Pages 1178: & lsquo;Let Me Know If There & rsquo;s Anything I Can Do for You & rsquo;, the Development of a Mobile Application for Adolescents and Young Adults (AYAs) with Cancer and Their Loved Ones to Reconnect after Diagnosis
This study describes the cocreational process, the characteristics of the users and their expectations regarding the app. 121 AYA cancer patients and 37 loved ones completed a questionnaire. 68.6% of the loved ones reported ‘staying in contact’ and ‘finding out about the needs and wishes of ‘their AYA’ during this time’ as the main reasons for downloading the application. 41.1% of the AYA cancer patients expected the app to help them communicate to their loved ones what they do or don’t want and need. 60% of the loved ones ind...
Source: Cancers - February 24, 2022 Category: Cancer & Oncology Authors: Sophia H. E. Sleeman Milou J. P. Reuvers Eveliene Manten-Horst Bram Verhees Pandora Patterson Silvie H. M. Janssen Olga Husson Tags: Article Source Type: research
Cancers, Vol. 15, Pages 880: Meta-Analysis of Modulated Electro-Hyperthermia and Tumor Treating Fields in the Treatment of Glioblastomas
Conclusions: Our meta-analysis showed that both mEHT and TTF can improve glioblastoma survival, and the most benefit may be achieved in newly diagnosed cases.
Source: Cancers - January 31, 2023 Category: Cancer & Oncology Authors: Attila Marcell Szasz Elisabeth Estefan ía Arrojo Alvarez Giammaria Fiorentini Magdolna Herold Zoltan Herold Donatella Sarti Magdolna Dank Tags: Systematic Review Source Type: research
Cancers, Vol. 15, Pages 3626: Perceptions of Canadian Radiation Oncologists, Medical Physicists, and Radiation Trainees about the Feasibility and Need of Boron Neutron Capture Therapy (BNCT) in Canada: A National Survey
Conclusions: Most ROs and MPs supported Canadian BNCT research and would refer patients. However, limited awareness and a lack of experiences remain a challenge. Educational sessions are needed to realize this innovative cancer treatment in Canada.
Source: Cancers - July 14, 2023 Category: Cancer & Oncology Authors: Al-Retage Al-Bader John Agapito Ming Pan Tags: Article Source Type: research
Cancers, Vol. 11, Pages 1932: Promising Colorectal Cancer Biomarkers for Precision Prevention and Therapy
Marina De Rosa
Colorectal cancer (CRC) has been ranked as the third most prevalent cancer worldwide. Indeed, it represents 10.2% of all cancer cases. It is also the second most common cause of cancer mortality, and accounted for about 9.2% of all cancer deaths in 2018. Early detection together with a correct diagnosis and staging remains the most effective clinical strategy in terms of disease recovery. Thanks to advances in diagnostic techniques, and improvements of surgical adjuvant and palliative therapies, the mortality rate of CRC has decreased by more than 20% in the last decade. Cancer biomarkers for the early ...
Source: Cancers - December 3, 2019 Category: Cancer & Oncology Authors: Mimmo Turano Paolo Delrio Daniela Rega Francesca Cammarota Alessia Polverino Francesca Duraturo Paola Izzo Marina De Rosa Tags: Review Source Type: research
Cancers, Vol. 12, Pages 303: CD22 Expression in B-Cell Acute Lymphoblastic Leukemia: Biological Significance and Implications for Inotuzumab Therapy in Adults
Malavasi
CD22 is a surface molecule expressed early during the ontogeny of B cells in the bone marrow and spleen, and can be found on B cells isolated from the different lymphoid compartments in humans. CD22 is expressed by most blasts from the majority (60–90%) of B-cell acute lymphoblastic leukemia (B-ALL). Current therapies in adults with newly diagnosed B-ALL are associated with complete remission (CR) rates of 50–90%. However, 30–60% of these patients relapse, and only 25–40% achieve disease-free survival of three years or more. Chemotherapy regimens for ...
Source: Cancers - January 27, 2020 Category: Cancer & Oncology Authors: Lanza Maffini Rondoni Massari Faini Malavasi Tags: Review Source Type: research
Cancers, Vol. 12, Pages 408: Outcomes Associated with First-Line anti-PD-1/ PD-L1 agents vs. Sunitinib in Patients with Sarcomatoid Renal Cell Carcinoma: A Systematic Review and Meta-Analysis
Imbimbo
De Placido
Lorenzo
: Immunotherapy based on anti PD-1/PD-L1 inhibitors has proven to be more effective than sunitinib in the first-line setting of advanced renal cell carcinoma (RCC). RCC patients with sarcomatoid histology (sRCC) have a poor prognosis and limited therapeutic options. We performed a systematic review and a meta-analysis of randomized-controlled trials (RCTs) of first-line anti PD-1/PDL-1 agents vs. sunitinib, presenting efficacy data in the sub-group of sRCC patients. The systematic research was conducted on Google Scholar, Cochrane Library, PubMed and Embase and updated until 31th Janu...
Source: Cancers - February 9, 2020 Category: Cancer & Oncology Authors: Buonerba Dolce Iaccarino Scafuri Verde Costabile Pagliuca Morra Riccio Ribera De Placido Romeo Crocetto Longo Imbimbo De Placido Lorenzo Tags: Review Source Type: research
Cancers, Vol. 13, Pages 1339: Neuroendocrine-Related Circulating Transcripts in Small-Cell Lung Cancers: Detection Methods and Future Perspectives
icco
Antonio Rossi
No well-established prognostic or predictive molecular markers of small-cell lung cancer (SCLC) are currently available; therefore, all patients receive standard treatment. Adequate quantities and quality of tissue samples are frequently unavailable to perform a molecular analysis of SCLC, which appears more heterogeneous and dynamic than expected. The implementation of techniques to study circulating tumor cells could offer a suitable alternative to expand the knowledge of the molecular basis of a tumor. In this context, the advantage of SCLC circulating cells to express some specific markers to b...
Source: Cancers - March 16, 2021 Category: Cancer & Oncology Authors: Lucia Anna Muscarella Tommaso Mazza Federico Pio Fabrizio Angelo Sparaneo Vito D ’Alessandro Antonio Tancredi Domenico Trombetta Flavia Centra Silvana Pia Muscarella Concetta Martina Di Micco Antonio Rossi Tags: Review Source Type: research
