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IJERPH, Vol. 20, Pages 5108: Retinal Microvasculature and Neural Changes and Dietary Patterns in an Older Population in Southern Italy
Conclusions: Eating habits and food consumption may be important risk factors for age-related retinal changes. A diet that provides the optimal intake of specific nutrients with antioxidant and anti-inflammatory powers, including carotenoids and omega-3 fatty acids, could have beneficial effects.
Source: International Journal of Environmental Research and Public Health - March 14, 2023 Category: Environmental Health Authors: Rossella Tatoli Luisa Lampignano Rossella Donghia Alfredo Niro Fabio Castellana Ilaria Bortone Roberta Zupo Sarah Tirelli Madia Lozupone Francesco Panza Giovanni Alessio Francesco Boscia Giancarlo Sborgia on behalf of the Eye Clinic Research Group on beha Tags: Article Source Type: research
Correlation between sKL and Nrf2 plasma levels and calcium oxalate urolithiasis
ConclusionPlasma sKL level decreased and Nrf2 level increased in patients with calcium oxalate calculi. Plasma sKL may play an antioxidant role in the pathogenesis of calcium oxalate stones through Nrf2 antioxidant pathway.
Source: International Urology and Nephrology - June 27, 2023 Category: Urology & Nephrology Source Type: research
The role of antioxidant response and nonphotochemical quenching of chlorophyll fluorescence in long-term adaptation to Cu-induced stress in Chlamydomonas reinhardtii
Environ Sci Pollut Res Int. 2023 Apr 27. doi: 10.1007/s11356-023-27175-y. Online ahead of print.ABSTRACTCopper is an essential micronutrient, but at supraoptimal concentrations it is also highly toxic, inducing oxidative stress and disrupting photosynthesis. The aim of the present study was to analyze selected protective mechanisms in strains of Chlamydomonas reinhardtii adapted and not adapted for growth in the presence of elevated copper concentrations. Two algal lines (tolerant and non-tolerant to high Cu2+ concentrations) were used in experiments to study photosynthetic pigment content, peroxidase activity, and non-pho...
Source: Environmental Science and Pollution Research International - April 27, 2023 Category: Environmental Health Authors: Bartosz Pluci ński Beatrycze Nowicka Andrzej Waloszek Joanna Rutkowska Kazimierz Strza łka Source Type: research
Comparison on Metabolism of Estradiol and Its 17-Sulfate by Recombinant Human CYP Isoforms
Biol Pharm Bull. 2021;44(9):1344-1347. doi: 10.1248/bpb.b21-00275.ABSTRACTTo identify the CYP isoforms involved in the production of 2-hydroxyestradiol 17-sulfate (2-OH-ES), which we assume to be an antioxidant in vivo, the 2-hydroxylation reaction of estradiol 17-sulfate (ES) by human liver microsome was investigated. As a result, it was estimated that CYP2C8 and 2C9 were largely involved in the production of 2-OH-ES. Therefore, the 2-hydroxylation kinetic analysis of ES was performed for both CYPs, and the metabolic clearance Vmax/Km (µL/nmol CYP/min) was determined. On comparing the results of ES with those of estradio...
Source: Biological and Pharmaceutical Bulletin - September 2, 2021 Category: Drugs & Pharmacology Authors: Shinji Yuasa Kaori Takanashi Kenta Ukiana Yoshihiro Mihara Shinji Itoh Source Type: research
