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Total 116800 results found since Jan 2013.
Knowledge of and adherence to radiographic guidelines for low back pain: a survey of chiropractors in Newfoundland and Labrador, Canada
ConclusionsWhile many chiropractors in this sample reported being unsure of specific radiographic guidelines, the majority of respondents adhered to guideline recommendations measured using clinical vignettes. Nonetheless, a small proportion still hold beliefs about radiographs for LBP that are discordant with current radiographic guidelines. Future research should aim to determine barriers to guideline uptake in this population in order to design and evaluate tailored knowledge translation strategies to reduce unnecessary LBP imaging.
Source: Chiropractic and Manual Therapies - January 18, 2021 Category: Complementary Medicine Source Type: research
New Phase 3b Psoriatic Arthritis (PsA) Data Show First-in-Class TREMFYA ® (guselkumab) Achieved Robust Joint Symptom Improvement and Complete Skin Clearance in Patients with Inadequate Response to Tumor Necrosis Factor Inhibition (TNFi-IR)
SPRING HOUSE, PENNSYLVANIA, June 2, 2021 – Today the Janssen Pharmaceutical Companies of Johnson & Johnson announced new efficacy and safety data for first-in-class TREMFYA® (guselkumab), including data from the first study evaluating a selective IL-23 inhibitor in adult patients with active PsA, all of whom had demonstrated inadequate response or intolerance to TNFi.1 In the COSMOS Phase 3b study, significantly higher proportions of patients treated with TREMFYA showed joint symptom improvement and complete skin clearance versus placebo at week 24 in this true TNFi-IRa patient population, which is often more diffic...
Source: Johnson and Johnson - June 2, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Mandibular and palatal tori exposed by trauma are risk factors for medication-related osteonecrosis of the jaws: a report from the Copenhagen ONJ cohort
ConclusionsHere, we reported a series of 29 cases of MRONJ with related mandibular or palatal tori among 391 consecutive patients in the Copenhagen ONJ Cohort . We documented that 59% of these cases were associated with trauma, and that in some cases, trauma was preventable (e.g., trauma from impression taking and intubation). Dentists as well as anesthesiologists should be aware of the presence of tori in patients on antiresorptive therapy. Surgical treatment was more successful (100%) compared with nonsurgical treatment (40%).
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - December 15, 2019 Category: ENT & OMF Source Type: research
‘The situation and the uncertainty about the coming result scared me but interaction with the radiographers helped me through’: a qualitative study on patients' experiences of magnetic resonance imaging examinations
ConclusionsOur study has provided a deeper understanding of the expectations before, and experiences during, a head‐first magnetic resonance imaging scan. Valuable insight into patients' apprehension about written and verbal information was obtained. The patients reported how they coped with the unfamiliar and stressful magnetic resonance imaging scanning procedure. A trustful dialogue with the radiographer was described as being crucial for patients' ability to manage fear, discomfort and feelings of loss of self‐control. We suggest a need for individualised information based on patient participation.
Relevance to cli...
Source: Journal of Clinical Nursing - October 14, 2013 Category: Nursing Authors: Sofia Carlsson, Eva Carlsson Tags: Nursing care standards and competencies Source Type: research
Abstract IA41: Emerging Issues in Cancer Screening for Racial and Ethnic Minorities
Cancer screening plays an important role in early detection; detecting cancer in an early stage has important implications for cancer health disparities. Considerable efforts have been made to increase access to early detection services among racial and ethnic minorities in order to improve cancer outcomes in these populations. However, our recent work has shown that racial disparities in cancer screening continue to exist. For instance, about 40% of women in our national random survey of cultural considerations in cancer screening were not up-to-date with mammography guidelines. Our other work with a community-based sampl...
Source: Cancer Epidemiology Biomarkers and Prevention - February 4, 2017 Category: Cancer & Oncology Authors: Halbert, C. H. Tags: Who, How, and When? Oral Presentations - Invited Abstracts Source Type: research
Janssen Presents New Data Demonstrating the Combination of Niraparib and Abiraterone Acetate Plus Prednisone Significantly Improved Radiographic Progression-Free Survival as a First-Line Therapy in Patients with HRR Gene-Mutated Metastatic Castration-Resistant Prostate Cancer
SAN FRANCISCO, Feb. 14, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced initial results from the Phase 3 MAGNITUDE study evaluating the investigational use of niraparib, a selective poly-ADP ribose polymerase (PARP) inhibitor, in combination with abiraterone acetate plus prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) with or without specific homologous recombination repair (HRR) gene alterations. At the final analysis for radiographic progression-free survival (rPFS), the treatment combination of niraparib and abiraterone acetate plus prednisone de...
Source: Johnson and Johnson - February 14, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Janssen Submits New Drug Application to the U.S. Food and Drug Administration Seeking Approval of Niraparib and Abiraterone Acetate Dual-Action Tablet, Plus Prednisone, as a First-Line Targeted Treatment for Patients with Metastatic Castration-Resistant Prostate Cancer with BRCA Gene Mutations
RARITAN, N.J., February 28, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval of niraparib in combination with abiraterone acetate, in the form of a dual-action tablet (DAT), plus prednisone, for the treatment of patients with BRCA-positive metastatic castration-resistant prostate cancer (mCRPC). If approved, this will be the first DAT formulation available in the U.S. to patients with mCRPC with BRCA mutations, which are a type of homologous recombination repair (HRR) gene alt...
Source: Johnson and Johnson - March 1, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Consultation for child physical abuse: Beyond the history and physical examination.
CONCLUSION: In proposing this approach, we aim both to make transparent and spark discussion about the way we work and to answer questions about the role of child abuse clinicians raised by recent interest in this subject by the mass media.
PMID: 33158586 [PubMed - as supplied by publisher]
Source: Child Abuse and Neglect - November 3, 2020 Category: Child Development Authors: Asnes AG, Pavlovic L, Moller B, Schaeffer P, Leventhal JM Tags: Child Abuse Negl Source Type: research
Simultaneous Development of Dieterich Disease and Freiberg Disease
We report a 65-year-old man consulting for inflammatory pain in his right hand of 1 month's duration and also in his right foot of 4 months' duration. The rheumatology department was consulted to rule out systemic disease because the synovitis had occurred simultaneously in 2 different locations. The plain radiography and magnetic resonance imaging findings supported the diagnosis of Dieterich disease and Freiberg disease, although only increased uptake was found on scintigraphy in the affected zones. Few studies have been published about Dieterich disease, most in case report form. To our knowledge, only 1 study has descr...
Source: Journal of Foot and Ankle Surgery - January 30, 2013 Category: Orthopaedics Authors: Xavier Conesa, Xavier González, Eduard Siles, Fèlix Parals, Josep Novell Tags: Case Reports and Series Source Type: research
The imaging characteristics of odontogenic myxoma and a comparison of three different imaging modalities
Conclusions: All 3 radiographic techniques, conventional radiography, CT, and magnetic resonance imaging (MRI), have inherent advantages and disadvantages; however, all 3 should be routinely used in the diagnosis of OM. The results of CT and MRI can accurately reveal margins of tumors and greatly aid in diagnosis.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - August 22, 2013 Category: ENT & OMF Authors: Eman Kheir, Lawrence Stephen, Christoffel Nortje, Leon Janse van Rensburg, Fadi Titinchi Tags: Oral and Maxillofacial Radiology Source Type: research
Diagnosis and management of hemoptysis.
This article aims to provide a comprehensive literature review on hemoptysis, analyzing its causes and pathophysiologic mechanisms, and providing details about anatomy and imaging of systemic bronchial and nonbronchial arteries responsible for hemoptysis. Strengths and limits of chest radiography, bronchoscopy, multidetector computed tomography (MDCT), MDCT angiography and digital subtraction angiography to assess the cause and lead the treatment of hemoptysis were reported, with particular emphasis on MDCT angiography. Treatment options for recurrent or massive hemoptysis were summarized, highlighting the predominant role...
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - April 30, 2014 Category: Radiology Authors: Larici AR, Franchi P, Occhipinti M, Contegiacomo A, Del Ciello A, Calandriello L, Storto ML, Marano R, Bonomo L Tags: Diagn Interv Radiol Source Type: research
Atrophic Maxilla Reconstruction With Fresh Frozen Allograft Bone, Titanium Mesh, and Platelet-Rich Fibrin: Case Report
The purpose of this article was to report the clinical and radiographic findings about a case of a man affected by severely atrophic maxilla to demonstrate the clinical proceedings associated with alveolar reconstruction destined for dental implant rehabilitation. The 3-dimensional augmentation of the alveolar ridge with the use of fresh-frozen bone graft, platelet-rich fibrin membrane, and t itanium mesh suggests potential benefits to the development of the bone formation physiology. The treatment combination may result in an optimal prognosis and represents an option for reconstruction of bone defects.
Source: Transplantation Proceedings - April 28, 2017 Category: Transplant Surgery Authors: R.C.F. Baldan, F.L. Coracin, L. Lins, W.R. Mello, P.S. Santos Tags: 15th Portuguese-Brazilian Congress, 13th Portuguese Transplant Congress, and 2nd Iberic Transplant Meeting Source Type: research
A five-year prospective study of spinal radiographic progression and its predictors in men and women with ankylosing spondylitis
Knowledge about predictors of new spinal bone formation in patients with ankylosing spondylitis (AS) is limited. AS-related spinal alterations are more common in men; however, knowledge of whether predictors d...
Source: Arthritis Research and Therapy - August 3, 2018 Category: Rheumatology Authors: Anna Deminger, Eva Klingberg, Mats Geijer, Jan G öthlin, Martin Hedberg, Eva Rehnberg, Hans Carlsten, Lennart T. Jacobsson and Helena Forsblad-d’Elia Tags: Research article Source Type: research
Acute midfoot injuries and their management
This article summarizes the current literature about the midfoot injuries and focuses in their management.
Source: Orthopaedics and Trauma - October 31, 2018 Category: Orthopaedics Authors: Efthymios Iliopoulos Tags: Foot and ankle trauma Source Type: research
The synergetic effect of pelvic rotation and X-ray offset on radiographic angles of the acetabular cup
In this study, a cone model for three-dimensional circle-to-two-dimensional ellipse projection is utilized to incorporate the effect of X-ray offset and quantify the relationships of the radiographic angles of the cup with the true orientation of the cup and pelvic rotations in either pelvic or hip anteroposterior radiographic situation.
Source: Medical and Biological Engineering and Computing - September 8, 2019 Category: Biomedical Engineering Source Type: research
