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A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

Clot resolution after 3 weeks of anticoagulant treatment of pulmonary embolism: comparison of computed tomography and perfusion scintigraphy
ConclusionIn patients with acute PE, only 3 weeks of anticoagulant treatment leads to complete clot resolution in a considerable proportion of patients and normalization is more often observed with CT‐scan than with Q‐scan.© 2013 International Society on Thrombosis and Haemostasis
Source: Journal of Thrombosis and Haemostasis - January 24, 2013 Category: Hematology Authors: J. Es, R. A. Douma, P. W. Kamphuisen, V. E.A. Gerdes, P. Verhamme, P. S. Wells, H. Bounameaux, A. W.A. Lensing, H. R. Büller Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research

A Mismatch Between the Abnormalities in Diffusion- and Susceptibility-Weighted Magnetic Resonance Imaging May Represent an Acute Ischemic Penumbra with Misery Perfusion
In this study we make the first case report of blunt cervical trauma leading to a stroke, demonstrating the disparity between diffusion-weighted imaging (DWI) and SWI changes, or DWI-SWI mismatch, in the acute ischemic brain. The area of mismatch between a smaller DWI cytotoxic edema and a larger SWI misery perfusion in our patient matured into a complete infarction with time. The DWI-SWI mismatch may signify the presence of an ischemic penumbra, and provide information about viability of the brain tissue at risk of potential infarction if without early reperfusion.
Source: Journal of Stroke and Cerebrovascular Diseases - February 14, 2013 Category: Neurology Authors: Masayuki Fujioka, Kazuo Okuchi, Asami Iwamura, Toshiaki Taoka, Bo K. Siesjö Tags: Case Reports Source Type: research

Perfusion territories subtended by penetrating coronary arteries increase in size and decrease in number toward the subendocardium
Blood flow distribution within the myocardium and the location and extent of areas at risk in case of coronary artery disease are dependent on the distribution and morphology of intramural vascular crowns. Knowledge of the intramural vasculature is essential in novel multiscale and multiphysics modeling of the heart. For this study, eight canine hearts were analyzed with an imaging cryomicrotome, developed to acquire high-resolution spatial data on three-dimensional vascular structures. The obtained vasculature was skeletonized, and for each penetrating artery starting from the epicardium, the dependent vascular crown was ...
Source: AJP: Heart and Circulatory Physiology - February 15, 2014 Category: Cardiology Authors: van Horssen, P., van den Wijngaard, J. P. H. M., Brandt, M. J., Hoefer, I. E., Spaan, J. A. E., Siebes, M. Tags: VASCULAR BIOLOGY AND MICROCIRCULATION Source Type: research

Gastric inhibitory peptide, serotonin, and glucagon are unexpected chloride secretagogues in the rectal gland of the skate (Leucoraja erinacea)
Since the discovery of the rectal gland of the dogfish shark 50 years ago, experiments with this tissue have greatly aided our understanding of secondary active chloride secretion and the secretagogues responsible for this function. In contrast, very little is known about the rectal gland of skates. In the present experiments, we performed the first studies in the perfused rectal gland of the little skate (Leucoraja erinacea), an organ weighing less than one-tenth of the shark rectal gland. Our results indicate that the skate gland can be studied by modified perfusion techniques and in primary culture monolayers, and that ...
Source: AJP: Regulatory, Integrative and Comparative Physiology - May 1, 2014 Category: Physiology Authors: Kelley, C. A., Decker, S. E., Silva, P., Forrest, J. N. Tags: Hormones, Reproduction and Development Source Type: research

Increase of cortical cerebral blood flow and further cerebral microcirculatory effects of Serelaxin in a sheep model
In conclusion, the injection of a high dose of Serelaxin exerts quick effects on the cerebral microcirculation. Therefore, Serelaxin might be suitable to improve cortical microcirculation and exert neuroprotective effects in clinically relevant scenarios that involve cortical hypoperfusion. These findings need to be confirmed in relevant experimental settings involving cerebral cortical hypoperfusion and can possibly be translated into clinical practice.
Source: AJP: Heart and Circulatory Physiology - August 31, 2016 Category: Cardiology Authors: Bischoff, S. J., Schmidt, M., Lehmann, T., Irintchev, A., Schubert, H., Jung, C., Schwab, M., Huber, O., Matziolis, G., Schiffner, R. Tags: VASCULAR BIOLOGY AND MICROCIRCULATION Source Type: research

Subchondral pressures and perfusion during weight bearing
Joints withstand huge forces, but little is known about subchondral pressures and perfusion during loading. We developed an in vitro calf foot model to explore intraosseous pressure (IOP) and subchondral perfu...
Source: Journal of Orthopaedic Surgery and Research - June 29, 2020 Category: Orthopaedics Authors: Michael Beverly, Barbara E. Marks and David W Murray Tags: Research article Source Type: research

Abstract 353: Patient and Provider Awareness of Unnecessary Testing, Wasteful Medical Spending, and Choosing Wisely Session Title: Poster Session III
Conclusion: Both patients and healthcare providers underestimate the costs of wasteful medical spending, patients to a greater degree. Awareness in both groups of the Choosing Wisely campaign is low. Many patients and providers are cognizant of accurate reasons why a test might be unnecessary.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Winchester, D. E., Nguyen, L., Kline, K., Plumb, J., Huo, T., Beyth, R. Tags: Session Title: Poster Session III Source Type: research

Renal circulation and microcirculation during intra-abdominal hypertension in a porcine model.
CONCLUSIONS: CEUS is a safe, real-time dynamic, noninvasive and simple technique to evaluate renal microvascular perfusion in intra-abdominal hypertension. Descending slope, PI and AUC can be used for the diagnosis of the renal microvascular damage in a porcine model of IAP-induced renal impairment. Also, SDF on the surface of the kidney is a useful tool to evaluate the microcirculation of kidney but sublingual SDF imaging was barely useful. PMID: 26914119 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 27, 2016 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Hereditary Hemorrhagic Telangiectasia (Rendu‐Osler‐Weber syndrome): Evaluation of the liver involvement with CT and CT‐Angiography
Abstract Hepatic vascular lesions in Hereditary Hemorrhagic Telangiegctasia (Rendu‐Osler‐Weber syndrome) range from tiny telangiectases to large confluent focal vascular masses associated with transient perfusion abnormalities such as transient segmental enhancement. These intraparenchymal perfusion abnormalities are usually the result of arterioportal shunts associated with blood flow diversion. Three types of shunts between the major hepatic vessels may observed: a) arteriosystemic (hepatic artery to hepatic veins) b) portosystemic (portal vein to hepatic veins or vena cava) and c) arterioportal (hepatic artery to po...
Source: Journal of Gastroenterology and Hepatology - October 1, 2015 Category: Gastroenterology Authors: Nikos Courcoutsakis, Pashalis Peihaberis, Helen Erkotidou, Panos Prassopoulos Tags: Education and Imaging ‐ Hepatology Source Type: research

Reply to letter regarding submission entitled: Cracking the perfusion code? - Laser-assisted Indocyanine Green angiography and combined laser Doppler spectrophotometry for intraoperative evaluation of tissue perfusion in autologous breast reconstruction with DIEP or ms-TRAM flaps
We thank the authors for their inspiring comment. As we stated in our study fundamental microsurgical training as well as broad experience in judging flap perfusion and skin perfusion, respectively, is one of the most important surgeon ´s tools. Furthermore we need to advance new technologies to lower even minor complications such as perfusion-related partial flap/fat necrosis.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - January 6, 2017 Category: Cosmetic Surgery Authors: I. Ludolph, R.E. Horch, J.P. Beier Tags: Correspondence and Communications Source Type: research

The perfusion code of DIEP and ms-TRAM flaps is a hard nut to crack
We read with interest the article by Ludolph et al. entitled “Cracking the perfusion code?: Laser-assisted Indocyanine Green angiography and combined laser Doppler spectrophotometry for intraoperative evaluation of tissue perfusion in autologous breast reconstruction with DIEP or ms-TRAM flaps”.1 We completely agree with the authors that intraoperative ev aluation of flap perfusion can still be challenging. Such is especially true in those cases where flaps are composed of several angiosomes as is usually the case with the DIEP and ms-TRAM flaps.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - January 9, 2017 Category: Cosmetic Surgery Authors: Louis de Weerd, Thomas Sj öberg, James B. Mercer, Sven Weum Tags: Correspondence and Communications Source Type: research

Reply to letter regarding submission entitled: Cracking the perfusion code? – Laser-assisted indocyanine green angiography and combined laser Doppler spectrophotometry for intraoperative evaluation of tissue perfusion in autologous breast reconstruction with DIEP or ms-TRAM flaps
We thank the authors for their inspiring comment. As we stated in our study, fundamental microsurgical training as well as broad experience in judging flap perfusion and skin perfusion, respectively, is one of the most important surgeon's tools. Furthermore we need to advance new technologies to lower even minor complications such as perfusion-related partial flap/fat necrosis.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - January 6, 2017 Category: Cosmetic Surgery Authors: I. Ludolph, R.E. Horch, J.P. Beier Tags: Correspondence and Communications Source Type: research

Fetal Major Cardiac Defects and Placental Dysfunction at 11–13 Weeks’ Gestation
(Abstracted from Ultrasound Obstet Gynecol 2018;51:194–198) Major congenital heart defects (CHDs) are those that require invasive interventions within the first year following birth and are often associated with fetal growth restriction (FGR). A recent study on isolated major CHDs found evidence of impaired placental angiogenesis in the absence of impaired placental perfusion and function in pregnancies with fetal CHD.
Source: Obstetrical and Gynecological Survey - July 1, 2018 Category: OBGYN Tags: OBSTETRICS: PHYSIOLOGY & PATHOPHYSIOLOGY OF PREGNANCY, LABOR, AND THE PUERPERIUM Source Type: research

Tumor vasculature remolding by thalidomide increases delivery and efficacy of cisplatin
A promising strategy to overcome the chemoresistance is the tumor blood vessel normalization, which restores the physiological perfusion and oxygenation of tumor vasculature. Thalidomide (Thal) has been shown ...
Source: Journal of Experimental and Clinical Cancer Research - October 28, 2019 Category: Cancer & Oncology Authors: Yanwei Shen, Shuting Li, Xin Wang, Mengying Wang, Qi Tian, Jiao Yang, Jichang Wang, Biyuan Wang, Peijun Liu and Jin Yang Tags: Research Source Type: research